id
stringlengths
6
42
title
stringlengths
3
499
abstract
stringlengths
0
6.24k
label
listlengths
0
6
W2066667805
Between Give and Take: A Clinical Guide to Contextual Therapy
In this volume, Boszormenyi-Nagy and Krasner provide a comprehensive, sharply focused guide to the clinical use of Contextual Therapy (CT) as a therapy rooted in the reality of human relationships. The authors describe a far-reaching trust-based approach to individual freedom and interpersonal fairness that makes possi...
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
W2149832764
Frequency dependence of the reorientational motion of OD bonds of deuterated methanol in liquid phase: A first principles molecular dynamics study
Abstract We present an ab initio molecular dynamics study of the frequency dependence of rotational motion of OD bonds of deuterated methanol in liquid phase. A time series analysis of the simulated trajectories is performed to calculate the fluctuating frequencies of the OD bonds and the frequency-resolved rotational ...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
172798
Personalised risk assessment in febrile illness to optimise real-life management across the european union
The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are ...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1126/scisignal.aaf6625
Pressure-induced oxidative activation of PKG enables vasoregulation by Ca<sup>2+</sup> sparks and BK channels
Activation of Ca2+-sensitive, large-conductance potassium (BK) channels in vascular smooth muscle cells (VSMCs) by local, ryanodine receptor-mediated Ca2+ signals (Ca2+ sparks) acts as a brake on pressure-induced (myogenic) vasoconstriction-a fundamental mechanism that regulates blood flow in small resistance arteries....
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
250290
THE HYGIENE HYPOTHESIS : REVISITING THE CONCEPT BY INTEGRATING EPIDEMIOLOGY AND MECHANISTIC STUDIES
The hygiene hypothesis postulating the paradoxical protective role of infections on immune-mediated diseases including atopy (i.e. atopic dermatitis, rhinitis, asthma) and more recently autoimmune diseases has been the matter of extensive investigation. The aim of the present project is to validate this hypothesis inte...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2011708825
Distant entanglement protected through artificially increased local temperature
In composed quantum systems, the presence of local dissipative channels causes loss of coherence and entanglement at a rate that grows with the temperature of the reservoirs. However, here we show that if temperature is artificially added to the system, entanglement decay can be significantly slowed down or even suppre...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics" ]
643585
Smart restoration with particle infused repointing
The objective of the proposed project is the development of a damage sensing material for application in structures of architectural heritage. This material comprises lime mortar infused with conductive carbon nano-particles, applicable for repair and strengthening of historic masonry buildings through repointing of mo...
[ "Materials Engineering", "Products and Processes Engineering", "Synthetic Chemistry and Materials" ]
interreg_4046
Policies & Measures to Support Local & Regional Innovation Ecosystems
The transfer of innovation and knowledge produced by the RTOs (Research and Technological Organisations) and higher education to the local & regional businesses remains one of the most important gaps and difficulties in terms of Innovation & Growth. It is key to generate economic exploitation of the R&D results and pa...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space" ]
250050
Gene transfer techniques in the treatment of cardiovascular diseases and malignant glioma
Background: Poor angiogenesis and collateral vessel formation lead to coronary heart disease, claudication, infarctions and amputations while malignant glioma is one of the most aggressive proangiogenic tumors leading to death in a few months. For these diseases either stimulation or blocking, respectively, of angiogen...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
339541
AMPA Receptor Dynamic Organization and Synaptic transmission in health and disease
AMPA glutamate receptors (AMPAR) play key roles in information processing by the brain as they mediate nearly all fast excitatory synaptic transmission. Their spatio-temporal organization in the post synapse with respect to presynaptic glutamate release sites is a key determinant in synaptic transmission. The activity-...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Computer Science and Informatics" ]
W2057429385
Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy in metastatic colorectal cancer and pharmacogenetic analysis
To evaluate the efficacy and safety of S-1 in combination with oxaliplatin in a biweekly schedule as first-line treatment in metastatic colorectal cancer and the association between genetic polymorphisms and treatment outcomes.Eligibility included age 18-75 years, at least one measurable lesion, no prior chemotherapy e...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
638760
Theory of statistical topological insulators
Topological insulators (TI) are a novel class of materials with insulating bulk and conducting surface. The conduction of the surface is protected by the topological properties of the bulk, as long as a fundamental symmetry is present (for instance time-reversal symmetry). My goal is to investigate to what limits does ...
[ "Condensed Matter Physics", "Mathematics" ]
715254
Do droughts self-propagate and self-intensify?
Droughts cause agricultural loss, forest mortality and drinking water scarcity. Their predicted increase in recurrence and intensity poses serious threats to future global food security. Several historically unprecedented droughts have already occurred over the last decade in Europe, Australia and the USA. The cost of ...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
10.1029/2009JB006918
Origin Of Deep Ocean Microseisms By Using Teleseismic Body Waves
Recent studies of oceanic microseisms have concentrated on fundamental mode surface waves. Extraction of fundamental mode Rayleigh and Love wave Green functions from station-station correlations of ambient seismic noise has recently been demonstrated to be a very powerful tool for imaging of the Earth's crust and upper...
[ "Earth System Science" ]
10.1007/s00334-014-0489-4
Recent advances in ancient DNA research and their implications for archaeobotany
The scope and ambition of biomolecular archaeology is undergoing rapid change due to the development of new ‘next generation’ sequencing (NGS) methods for analysis of ancient DNA in archaeological specimens. These methods have not yet been applied extensively to archaeobotanical material but their utility has been demo...
[ "The Study of the Human Past", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1088/0004-637X/800/2/109
No Time For Dead Time Timing Analysis Of Bright Black Hole Binaries With Nustar
Timing of high-count rate sources with the NuSTAR Small Explorer Mission requires specialized analysis techniques. NuSTAR was primarily designed for spectroscopic observations of sources with relatively low count-rates rather than for timing analysis of bright objects. The instrumental dead time per event is relatively...
[ "Universe Sciences", "Fundamental Constituents of Matter" ]
323148
Cellular determinants of neuronal plasticity on the level of single synapses in vivo
The search for the fundamental mechanisms of learning and experience-dependent memory formation in the brain has long been a central quest in neuroscience. The neocortex is a particularly relevant region for plasticity because it is involved in sensory, motor, and cognitive tasks with strong learning components. Howeve...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1017/S0066154617000072
Agricultural Innovation And Resilience In A Long Lived Early Farming Community The 1 500 Year Sequence At Neolithic To Early Chalcolithic Catalhoyuk Central Anatolia
Intensive archaeobotanical investigations at Catalhoyuk have created a unique opportunity to explore change and continuity in plant use through the ca 1,500-year Neolithic to early Chalcolithic sequence of an early established farming community. The combination of crops and herd animals in the earliest (Aceramic) part ...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.1063/1.4976212
Uniaxial Stress Tuned Large Magnetic Shape Memory Effect In Ni Co Mn Sb Heusler Alloys
Combined strain and magnetization measurements on the Heusler shape-memory alloys Ni45Co5Mn38Sb12 and Ni44Co6Mn38Sb12 give evidence for strong magneto-structural coupling. The sample length changes up to 1% at the martensitic transformation, between a ferromagnetic, austenitic phase at high temperatures and a weakly ma...
[ "Condensed Matter Physics", "Materials Engineering" ]
233325
RNA silencing in regulation and evolution
Small RNA is a specificity determinant of silencing mechanisms that can target RNA through base pairing to affect RNA stability and translation. This targeting process, directly or indirectly, can also target DNA and chromatin to introduce epigenetic modifications. In plants there are many hundreds of thousands - of ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
US 2004/0023864 W
PROCESS AND APPARATUS FOR COLLECTION OF CONTINUOUS FIBERS AS A UNIFORM BATT
A process and apparatus for collecting continuous fibers or filaments as a uniform batt comprises a filament emitter in the form of a spinning die, a venturi, a diffuser, and a fiber collection bed. The filaments move downward after being created by the emitter, and exhaust ports create in the diffuser an airflow havin...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1103/PhysRevB.95.220409
Magnon activation by hot electrons via nonquasiparticle states
We consider the situation when a femtosecond laser pulse creates a hot electron state in a half-metallic ferromagnet (e. g. , ferromagnetic semiconductor) on a picosecond time scale but does not act directly on the localized spin system. We show that the energy and magnetic moment transfer from hot itinerant electrons ...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
W1526754709
Settlement and Bearing Capacity of Foundations with Different Vertical Cross-sectional Shapes on Non-cohesive Soil Bases under Vertically Applied Load
Settlement and bearing capacity of foundation models with different vertical cross-sectional shapes on non-cohesive subsoil bases under the action of vertically applied load are presented. Models of foundations with rectangular, wedge and T vertical cross-sectional shapes were experimentally studied. The study generall...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1007/s10494-020-00147-9
Near-Wall Flame and Flow Measurements in an Optically Accessible SI Engine
Near-wall processes in internal combustion engines strongly affect heat transfer and pollutant emissions. With continuously improving capabilities to model near-wall processes, the demand for corresponding measurements increases. To obtain an in-depth understanding of the near-wall processes within spark-ignition engin...
[ "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
646625
Understanding and exploiting the insect P450 resistome
Insect resistance to synthetic insecticides and the anti-herbivore defence chemicals produced by many plants is an ongoing challenge to sustainable pest management while also an exceptional model system to study adaptive evolution. The cytochrome P450s are a superfamily of enzymes that are ubiquitous in nature, and one...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Biotechnology and Biosystems Engineering" ]
10.1084/jem.20141271
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation
B cell antigen receptor (BCR) signaling is critical for B cell development and activation. Using mass spectrometry, we identified a protein kinase D–interacting substrate of 220 kD (Kidins220)/ankyrin repeat–rich membrane-spanning protein (ARMS) as a novel interaction partner of resting and stimulated BCR. Upon BCR sti...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1016/j.sbi.2020.04.003
Practically useful protein-design methods combining phylogenetic and atomistic calculations
Our ability to design new or improved biomolecular activities depends on understanding the sequence-function relationships in proteins. The large size and fold complexity of most proteins, however, obscure these relationships, and protein-optimization methods continue to rely on laborious experimental iterations. Recen...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics" ]
US 201615148806 A
Washing Machine and Driving Apparatus Thereof
A driving apparatus for a washing machine includes a single-phase outer rotor brushless motor and a driving wheel. The motor drives the driving wheel and includes a stator and a rotor. The stator includes a stator core and windings wound around the stator core. The rotor includes a rotor yoke, and a permanent magnet. A...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1002/hyp.11313
Using high-resolution isotope data and alternative calibration strategies for a tracer-aided runoff model in a nested catchment
Testing hydrological models over different spatio-temporal scales is important for both evaluating diagnostics and aiding process understanding. High-frequency (6-hr) stable isotope sampling of rainfall and runoff was undertaken during 3-week periods in summer and winter within 12 months of daily sampling in a 3. 2-km2...
[ "Earth System Science", "Products and Processes Engineering" ]
EP 09167892 A
Stabplate connections
An underwater stabplate connection is provided by lowering a counterbalanced first part (2) of the connection in a horizontal disposition by a lift line (6), the first part being attached to an umbilical (1). The first part of the connection mates with a second part (8) of the connection, the second part being attached...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1007/s00334-012-0376-9
Is naked barley an eastern or a western crop? The combined evidence of archaeobotany and genetics
Forms of Hordeum vulgare ssp. vulgare (barley) that possess a naked caryopsis are an important human staple and are mainly found today in eastern Asia. However, naked barley has not always been an eastern crop: archaeobotanical data show that it was prevalent in Europe and the Near East during various periods in prehis...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.1080/14036096.2014.947082
Centring Housing In Political Economy
AbstractThe issue of “housing” has generally not been granted an important role in post-war political economy. Housing-as-policy has been the preserve of social policy analysis and of a growing field of housing studies; housing-as-market has been confined to mainstream economics. This paper insists that political-econo...
[ "Institutions, Governance and Legal Systems", "Individuals, Markets and Organisations" ]
10.1038/s41598-017-10783-3
A mutation in the melon Vacuolar Protein Sorting 41prevents systemic infection of Cucumber mosaic virus
In the melon exotic accession PI 161375, the gene cmv1, confers recessive resistance to Cucumber mosaic virus (CMV) strains of subgroup II. cmv1 prevents the systemic infection by restricting the virus to the bundle sheath cells and impeding viral loading to the phloem. Here we report the fine mapping and cloning of cm...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Immunity, Infection and Immunotherapy" ]
10.1007/JHEP03(2015)143
Asymptotic Symmetries Of Three Dimensional Higher Spin Gravity The Metric Approach
The asymptotic structure of three-dimensional higher-spin anti-de Sitter gravity is analyzed in the metric approach, in which the fields are described by completely symmetric tensors and the dynamics is determined by the standard Einstein-Fronsdal action improved by higher order terms that secure gauge invariance. Prec...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1002/pro.3126
Incorporating an allosteric regulatory site in an antibody through backbone design
Allosteric regulation underlies living cells' ability to sense changes in nutrient and signaling-molecule concentrations, but the ability to computationally design allosteric regulation into non-allosteric proteins has been elusive. Allosteric-site design is complicated by the requirement to encode the relative stabili...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1051/0004-6361/201423800
Ip Eridani A Surprising Long Period Binary System Hosting A He White Dwarf
We determine the orbital elements for the K0 IV + white dwarf (WD) system IP Eri, which appears to have a surprisingly long period of 1071 d and a significant eccentricity of 0. 25. Previous spectroscopic analyses of the WD, based on a distance of 101 pc inferred from its Hipparcos parallax, yielded a mass of only 0. 4...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.5194/acp-13-10285-2013
The analysis of size-segregated cloud condensation nuclei counter (CCNC) data and its implications for cloud droplet activation
Abstract. Ambient aerosol, CCN (cloud condensation nuclei) and hygroscopic properties were measured with a size-segregated CCNC (cloud condensation nuclei counter) in a boreal environment of southern Finland at the SMEAR (Station for Measuring Ecosystem-Atmosphere Relations) II station. The instrumental setup operated ...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
980925
The first percutaneous paddle lead for spinal cord stimulation (scs)
Chronic Pain is one of the most common conditions for which people seek medical attention: around 20% of adult Europeans and 27% of the US are affected with moderate to severe intensity by such syndrome. Chronic pain has serious impacts on their quality of life, including impaired physical and social functioning and re...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Products and Processes Engineering", "Materials Engineering" ]
10.1016/j.seppur.2015.07.019
Removal of VOCs at trace concentration levels from humid air by Microwave Swing Adsorption, kinetics and proper sorbent selection
Microwave Swing Adsorption, MWSA, is already established as an alternative way of heating and regenerating solids efficiently in adsorption operations. When zeolites are used for MWSA applications it becomes necessary to tailor the zeolite properties towards microwave heating while at the same time aiming to obtain the...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1038/nphys3675
Directed percolation phase transition to sustained turbulence in Couette flow
Turbulence is one of the most frequently encountered non-equilibrium phenomena in nature, yet characterizing the transition that gives rise to turbulence in basic shear flows has remained an elusive task. Although, in recent studies, critical points marking the onset of sustained turbulence have been determined for sev...
[ "Condensed Matter Physics" ]
10.1038/nn.4303
Spatially segregated feedforward and feedback neurons support differential odor processing in the lateral entorhinal cortex
The lateral entorhinal cortex (LEC) computes and transfers olfactory information from the olfactory bulb to the hippocampus. Here we established LEC connectivity to upstream and downstream brain regions to understand how the LEC processes olfactory information. We report that, in layer II (LII), reelin- and calbindin-p...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
W2110975861
The Yin and Yang of processing data warehousing queries on GPU devices
Database community has made significant research efforts to optimize query processing on GPUs in the past few years. However, we can hardly find that GPUs have been truly adopted in major warehousing production systems. Preparing to merge GPUs to the warehousing systems, we have identified and addressed several critica...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1177/0162243919828107
Science And Technology Studies In Policy The Uk Synthetic Biology Roadmap
In this paper, we reflect on our experience as Science and Technology Studies (STS) researchers who were members of the working group that produced A Synthetic Biology Roadmap for the UK in 2012. We explore how this initiative sought to govern an uncertain future, and describe how it was successfully used to mobilize p...
[ "Institutions, Governance and Legal Systems", "The Social World and Its Interactions", "Biotechnology and Biosystems Engineering" ]
788793
Unveiling the relationship between brain connectivity and function by integrated photonics
I will address the fundamental question of which is the role of neuron activity and plasticity in information elaboration and storage in the brain. I, together with an interdisciplinary team, will develop a hybrid neuro-morphic computing platform. Integrated photonic circuits will be interfaced to both electronic circu...
[ "Neuroscience and Disorders of the Nervous System", "Systems and Communication Engineering", "Computer Science and Informatics", "Condensed Matter Physics" ]
CA 2275361 A
MAKE-UP COMPACT WITH SEALING JOINT
L'invention est relative à un boîtier comportant un couvercle et un corps de boîtier ajouré, recevant une réserve de produit contenue dans une coupelle. Il comporte un joint d'étanchéité (6) assujetti à la coupelle (5) et s'appliquant de manière étanche sur le corps de boîtier (2).
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1038/ng.874
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
A20 (TNFAIP3) is a protein that is involved in the negative feedback regulation of NF-°B signaling in response to specific proinflammatory stimuli in different cell types and has been suggested as a susceptibility gene for rheumatoid arthritis. To define the contribution of A20 to rheumatoid arthritis pathology, we gen...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.3982/ECTA11455
A Theory Of The Stakeholder Corporation
There is a widely held view within the general public that large corporations should act in the interests of a broader group of agents than just their shareholders (the stakeholder view). This paper presents a framework where this idea can be justified. The point of departure is the observation that a large firm typica...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1145/2480359.2429087
Abstract Conflict Driven Learning
Modern satisfiability solvers implement an algorithm, called Conflict Driven Clause Learning, which combines search for a model with analysis of conflicts. We show that this algorithm can be genera. . .
[ "Computer Science and Informatics" ]
759082
Topology of moduli spaces of Riemann surfaces
The proposal describes two main projects. Both of them concern cohomology of moduli spaces of Riemann surfaces, but the aims are rather different. The first is a natural continuation of my work on tautological rings, which I intend to work on with Qizheng Yin and Mehdi Tavakol. In this project, we will introduce a new...
[ "Mathematics" ]
US 2007/0065014 W
METHOD AND SYSTEM FOR FORMING A NON-CIRCULAR BOREHOLE
System and methods for creating shaped, non-circular boreholes in rocks especially for use with geothermal heat pump applications and for increasing wellbore support in applications such as horizontal oil and gas drilling are described. The systems and methods when applied to geothermal heat pumps create an elliptical ...
[ "Products and Processes Engineering", "Earth System Science" ]
891610
Safe and sensible tissue graspers for pediatric and (mini-)laparoscopic surgery
Laparoscopic surgery is the most common surgical intervention with over 15 million procedures performed annually worldwide. Most recently, the Dutch Healthcare Inspectorate shocked the medical community when discovering the risk of patient complications is 2-4% higher per laparoscopic operation as compared to its outda...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1145/2393596.2393664
Conditional Model Checking A Technique To Pass Information Between Verifiers
Software model checking, as an undecidable problem, has three possible outcomes: (1) the program satisfies the specification, (2) the program does not satisfy the specification, and (3) the model checker fails. The third outcome usually manifests itself in a space-out, time-out, or one component of the verification too...
[ "Computer Science and Informatics" ]
10.1021/nn402927q
In situ observations of the atomistic mechanisms of Ni catalyzed low temperature graphene growth
The key atomistic mechanisms of graphene formation on Ni for technologically relevant hydrocarbon exposures below 600 C are directly revealed via complementary in situ scanning tunneling microscopy and X-ray photoelectron spectroscopy. For clean Ni(111) below 500 C, two different surface carbide (Ni2C) conversion mecha...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1111/1365-2664.12159
Understanding The Effects Of A New Grazing Policy The Impact Of Seasonal Grazing On Shrub Demography In The Inner Mongolian Steppe
1. Grazing by livestock is a common land use in arid and semi-arid areas. Developing sustainable grazing regimes that conserve vegetation and maintain productivity is therefore important in these ecosystems. To solve environmental problems induced by overgrazing in Chinese semi-arid regions, the Chinese government has ...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
Q2693813
Increasing the competitive advantage of Bratbud through the design development strategy
The subject of the project will be the development of a design audit at the “Bratbud” company, which will result in the creation of a design strategy. The project will enable the development of innovative solutions in the context of the company’s current activity, as well as the development of strategic development dir...
[ "Products and Processes Engineering", "Individuals, Markets and Organisations" ]
W2035323134
Managing disruption in an imperfect production–inventory system
A new real-time disruption recovery plan is developed.An imperfect production-inventory system is considered.A new mathematical and dynamic solution approach is developed for managing disruptions.We solved the problem for the both single and multiple disruptions on a real-time basis.We compared the results for a good n...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.5252/az2017n2a4
The worked bone industry and intrusive fauna associated with the prehistoric cave burials of Abri des Autours (Belgium)
The excavation of the Abri des Autours, a rock-shelter located in southern Belgium, enabled the discovery of three human burials, two dated to the Early Mesolithic and a third dated to the Middle Neolithic. In addition to the human bones, more than 200 faunal remains were uncovered. A taphonomic analysis was undertaken...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.1364/CLEO_AT.2016.AM2J.6
Ultrafast Electrooptic Dual Comb Interferometry Over 40 Nm Bandwidth
We combine dual-comb interferometry with coherent nonlinear spectral broadening. We show high-speed (sub-millisecond) mode-resolved electric-field complex measurements of 25 GHz electrooptic frequency combs spanning the whole C band (1530–1565 nm).
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1111/jcms.12815
Equality of Opportunity in a European Social Market Economy
This article investigates what role the ideal of equality of opportunity should play in a European social market economy (ESME). After defining ‘social market economy’ and sketching different conceptions of equality of opportunity, it is argued that a social market economy must implement a substantive version of equali...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1016/j.celrep.2017.12.037
Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions
Nuclear RNA metabolism is influenced by protein complexes connecting to both RNA-productive and -destructive pathways. The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with the nuclear exosome targeting (NEXT) complex, linking to RNA decay. To dissect ZC...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W1981475859
Ethylene-regulated (methylsulfanyl)alkanoate ester biosynthesis is likely to be modulated by precursor availability in Actinidia chinensis genotypes
The limiting steps of ethylene-dependent (methylsulfanyl)alkanoate ester biosynthesis have been investigated in this study, using closely related Actinidia chinensis genotypes and the commercial cultivar 'Hort16A'. Quantification of methylsulfanyl-compounds from the headspace of ethylene-producing kiwifruits revealed l...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
W4283257170
La literatura fantástica de César Vallejo: marginalidad y política «Los Cayanas»
La producción literaria de César Vallejo incluye una novela breve de carácter fantástico, Fabla Salvaje, y otros cuentos del mismo género, como «Los caynas», recogidos en 1923 en la segunda parte de la colección de cuentos Escalas. La primera parte del volumen, en cambio, es una muestra de la literatura carcelaria de V...
[ "The Study of the Human Past", "Texts and Concepts" ]
185030
Selection to outsmart the germs: the evolution of disease recognition and social cognition
An astounding example of human social complexity is the global healthcare industry, in which we perform lifesaving surgeries, eradicate childhood diseases, provide global vaccinations, and track the evolution and outbreak of novel zoonotic diseases. Surprisingly, all of this hinges on a cognitive ability whose evolutio...
[ "The Human Mind and Its Complexity", "Environmental Biology, Ecology and Evolution", "Immunity, Infection and Immunotherapy" ]
10.1109/LCOMM.2016.2598326
Joint Dimming Control And Transceiver Design For Mimo Aided Visible Light Communication
The multiple-input multiple-output (MIMO) concept has been readily invoked in visible light communication (VLC) for increasing data rate. In this letter, we conceive a general solution of dimming control and MIMO transceiver design for VLC, which is capable of minimizing the mean-squared error between the transmitted a...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
291319
Addressing global sustainability challenges by changing perceptions in catalyst design
One of the greatest challenges facing society is the sustainability of resources. At present, a step change in the sustainable use of resources is needed and catalysis lies at the heart of the solution by providing new routes to carbon dioxide mitigation, energy security and water conservation. It is clear that new hi...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Products and Processes Engineering" ]
US 2007/0021968 W
TESTING APPARATUS FOR APPLYING A STRESS TO A TEST SAMPLE
A testing apparatus which is suitable for applying a stress load to a test specimen is provided. The testing apparatus may be used to simulate lithostatic stress on a test specimen, which may be, for example, a portion of a geologic formation. The testing apparatus may also be used in a method of evaluating the expecte...
[ "Products and Processes Engineering", "Earth System Science" ]
NO 0200234 W
TRANSPORT, STORAGE AND DISTRIBUTION OF COMPRESSED NATURAL GAS
System for transport and storage of compressed natural gas (CNG) at high pressure (HP) and distribution of said natural gas at high pressure (HP), medium pressure (MP) and low pressure (LP), which system is distinguished in that the layout thereof is such that during fluid communication to or between units of the syste...
[ "Products and Processes Engineering", "Physical and Analytical Chemical Sciences" ]
10.1172/JCI84427
The Impact Of Hypoxia On Tumor Associated Macrophages
The role of tumor-associated macrophages (TAMs) in cancer is often correlated with poor prognosis, even though this statement should be interpreted with care, as the effects of macrophages primarily depend on their localization within the tumor. This versatile cell type orchestrates a broad spectrum of biological funct...
[ "Immunity, Infection and Immunotherapy", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W1985949821
Effects of surface tension on axisymmetric Hertzian contact problem
Abstract Surface tension plays an important role in micro/nanosized contact problems. Based on the solution of a point force acting on a half plane with surface tension, we consider the axisymmetric contact between a rigid sphere and an elastic half space. It is found that when the contact radius is comparable with the...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1051/0004-6361/201220706
Rx J0123 4 7321 A Be X Ray Binary In The Wing Of The Small Magellanic Cloud
Aims. To confirm faint Be/X-ray binary candidates from the XMM-Newton survey of the Small Magellanic Cloud, we searched for X-ray outbursts in archival ROSAT observations. We found that RX J0123. 4-7321 was much brighter when detected with ROSAT than seen 16 years later by XMM-Newton. Methods. We analysed the ROSAT obs...
[ "Universe Sciences" ]
W617587148
Indirect measurement method of inner wall temperature of scramjet with a state observer
A state observer-based method is developed for the indirect online measurement of the inner wall temperature using the out surface temperature and pressure of a scramjet combustor. A mathematical model is established to describe the heat transfer from gas to combustor wall and inside combustor wall as well. A proportio...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1016/j.ymeth.2014.03.020
A simple TALEN-based protocol for efficient genome-editing in Drosophila
Drosophila is a well-established genetic model organism: thousands of point mutations, deficiencies or transposon insertions are available from stock centres. However, to date, it is still difficult to modify a specific gene locus in a defined manner. A potential solution is the application of transcription activator-l...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.coviro.2011.10.003
Toward a quantitative understanding of viral phylogeography
Phylogeographic approaches help uncover the imprint that spatial epidemiological processes leave in the genomes of fast evolving viruses. Recent Bayesian inference methods that consider phylogenetic diffusion of discretely and continuously distributed traits offer a unique opportunity to explore genotypic and phenotypi...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics" ]
10.1111/add.12662
Longitudinal patterns of problematic computer game use among adolescents and adults-a 2-year panel study
Aims: To investigate the longitudinal patterns (stability and change) of problematic computer game use and its interdependencies with psychosocial wellbeing in different age groups. Design: Three-wave, annual panel study using computer-assisted telephone surveys. Setting: Germany. Participants: A total of 112 adolescen...
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
219323
Focus on advancing spatial and temporal resolution of 3d structured illumination microscopy
FASTR 3D SIM: Focus on Advancing the Spatial and Temporal Resolution of 3D Structured Illumination Microscopy Super-resolved structured illumination microscopy (SR-SIM) is an important method to surpass the resolution limit in fluorescence microscopy. SR-SIM is compatible with many fluorescent labels and ensures low p...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
W2363993460
Traceable Quality Control of Dialyzer
Objective To establish the quality control management system for the whole using process of dialyzer, and analyze quality control issues with pyramid model to monitor adverse actions to lay a solid foundation for quality management of dialyzer. Methods Each dialyzer is encoded with bar code by using dialysis management...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1146/annurev-biochem-061516-044617
A bright future for antibiotics?
Multidrug resistance is a global threat as the clinically available potent antibiotic drugs are becoming exceedingly scarce. For example, increasing drug resistance among gram-positive bacteria is responsible for approximately one-third of nosocomial infections. As ribosomes are a major target for these drugs, they may...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
US 77397196 A
Emergency-reporting system for rescue operations
A personal emergency-reporting system for recognizing the site of an emergency with simultaneous warning of the nearest emergency physician/medical personnel. A portable patient data unit is provided which contains a satellite-supported global positioning system, which communicates with a patient data acquisition and e...
[ "Systems and Communication Engineering", "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
interreg_842
Promotion of Multimodal Transport in Chemical Logistics
The chemical industry is an important economic sector in Central Europe with 117 billion Euro turnover and 340.000 employees. The chemical companies are important logistic stakeholders responsible for 8% of freight transport. The industry has the objective to strengthen multimodal transport and modal shift from road to...
[ "Products and Processes Engineering", "Human Mobility, Environment, and Space" ]
10.1007/s11082-017-1285-z
Electroluminescent cooling in intracavity light emitters: modeling and experiments
We develop a coupled electronic charge and photon transport simulation model to allow for deeper analysis of our recent experimental studies of intracavity double diode structures (DDSs). The studied structures consist of optically coupled AlGaAs/GaAs double heterojunction light emitting diode (LED) and GaAs p–n-homoju...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
W4312460439
„Der erste Franzose“
Mit der Dritten Republik setzt sich im Frankreich des ausgehenden 19. Jahrhunderts eine neue Ursprungserzählung durch, ein „Roman national“, an dessen Anfang der Gallierhäuptling Vercingétorix steht. Zwar ist dieser im Jahre 52 v. Chr. Cäsars römischen Legionen unterlegen, doch war dies, so die Deutung in den Schulbüch...
[ "Texts and Concepts", "The Study of the Human Past", "Studies of Cultures and Arts" ]
10.1128/JB.00054-17
Transcriptional Repressor Ptvr Regulates Phenotypic Tolerance To Vancomycin In Streptococcus Pneumoniae
Reversible or phenotypic tolerance to antibiotics within microbial populations has been implicated in treatment failure of chronic infections and development of persister cells. However, the molecular mechanisms regulating phenotypic drug tolerance are largely unknown. In this study, we identified a four-gene operon in...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
W1981769385
Perioperative management of the adult scoliosis patient
Scoliosis in adults presents a uniquely different set of challenges to spine surgeons than scoliosis in the pediatric and adolescent population. The outcome of the corrective procedure in adult deformity revolves not only on meticulous surgical planning and technique but also upon optimization of a host of perioperativ...
[ "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1073/pnas.1321596111
Dopamine prediction error responses integrate subjective value from different reward dimensions
Prediction error signals enable us to learn through experience. These experiences include economic choices between different rewards that vary along multiple dimensions. Therefore, an ideal way to reinforce economic choice is to encode a prediction error that reflects the subjective value integrated across these reward...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1145/3126594.3126645
Navifields Relevance Fields For Adaptive Vr Navigation
Virtual Reality allow users to explore virtual environments naturally, by moving their head and body. However, the size of the environments they can explore is limited by real world constraints, such as the tracking technology or the physical space available. Existing techniques removing these limitations often break t...
[ "Computer Science and Informatics" ]
637579
Autonomous Cellular Computers for Diagnosis
Early diagnostics based on multiple biomarkers is key in numerous diseases, yet current technologies for multiplexed detection are complicated and expensive. Living cells detect and process various environmental signals in parallel and can self-replicate, presenting an attractive platform for scalable and affordable au...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Biotechnology and Biosystems Engineering" ]
10.1109/TSP.2015.2500179
Lowner Based Blind Signal Separation Of Rational Functions With Applications
A new blind signal separation (BSS) technique is proposed, enabling a deterministic separation of signals into rational functions. Rational functions can take on a wide range of forms, such as the well-known pole-like shape. The approach is a possible alternative for the well-known independent component analysis when t...
[ "Mathematics", "Computer Science and Informatics", "Physical and Analytical Chemical Sciences" ]
10.1109/HAVE.2014.6954338
On The Discrimination Of Stiffness During Pressing And Pinching Of Virtual Springs
In this paper, we study the perception of stiffness while pressing and pinching virtual springs. These exploration events are highly relevant for telerobotics, but their influence on stiffness perception is largely unexplored. Our study contributes to the understanding of the limits of stiffness perception for human-ro...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
SG 2016050233 W
A BAKING MACHINE
A baking machine for cooking food in the shape of sphere is disclosed. The baking machine comprises a food heating plate configured for accommodating and heating food materials; a vibration means configured for generating vibrations in a plurality of directions and transmitting the vibrations to the food heating plate;...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1145/3240765.3240818
Industrial Experiences With Resource Management Under Software Randomization In Arinc653 Avionics Environments
Injecting randomization in different layers of the computing platform has been shown beneficial for security, resilience to software bugs and timing analysis. In this paper, with focus on the latter, we show our experience regarding memory and timing resource management when software randomization techniques are applie...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
US 2013/0049793 W
POWER CONVERTER WITH QUASI-ZERO POWER CONSUMPTION
A power converter system, method and device powers a load when coupled to the load and draws a quasi-zero amount of power from the power supply when not coupled to the load. The power converter system maintains an output voltage such that the power converter system is able to properly "wake-up" when a load is coupled b...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
US 2014/0016829 W
NOISE, VIBRATION, AND HARMONICS REDUCING SPROCKET TECHNOLOGY
A number of variations may include a sprocket using one or more slot(s) and/or compressive or elastic material in order to lower the NVH. A number of variations may include a sprocket which isolates the vibrations created by the impact of the chain with the sprocket so that the vibrations are prevented from traveling i...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1371/journal.pone.0084687
SHOOT GROWTH1 maintains arabidopsis epigenomes by regulating IBM1
Maintaining correct DNA and histone methylation patterns is essential for the development of all eukaryotes. In Arabidopsis, we identified SHOOT GROWTH1 (SG1), a novel protein involved in the control of gene methylation. SG1 contains both a Bromo-Adjacent Homology (BAH) domain found in several chromatin regulators and ...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
949080
Deciphering and Engineering the overlooked but Universal phenomenon of Subpopulations in BIOtechnology
Microbial bioproduction, despite being considered a paradigmatic sustainable alternative to petroleum-based chemistry, is often limited by low yields and productivities, which prevents commercialisation. It is generally known for all types of cells that genetically identical populations can form metabolically distinct ...
[ "Biotechnology and Biosystems Engineering", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1002/pan3.8
An ecological theory of changing human population dynamics
The dependence of humans on nature has come into focus as the human population continues to grow, resources diminish and production technology stagnates – threatening human well-being on a global scale. Numerous previous models describe human population dynamics, in relation to a multitude of different factors. However...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
770244
Defective protein translation as a pathogenic mechanism of peripheral neuropathy
Familial forms of neurodegenerative diseases are caused by mutations in a single gene. It is unknown whether distinct mutations in the same gene or in functionally related genes cause disease through similar or disparate mechanisms. Furthermore, the precise molecular mechanisms underlying virtually all neurodegenerativ...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.bpj.2015.05.009
2-Hydroxy Fatty Acid Enantiomers of Gb<inf>3</inf> Impact Shiga Toxin Binding and Membrane Organization
Shiga toxin subunit B (STxB) binding to its cellular receptor Gb3 leads to the formation of protein-lipid clusters and bending of the membrane. A newly developed synthetic route allowed synthesizing the biologically most relevant Gb3-C24:1 2OH species with both, the natural (Gb3-R) as well as the unnatural (Gb3-S) conf...
[ "Condensed Matter Physics", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
TR 2008000062 W
APPLICATION OF THE FINISHING MATERIAL ON THE WARP
The invention relates to a denim fabric production method comprising the process steps of thread production, rope winding, rope dyeing, rope opening in the denim fabric production, wherein during the size application process, a thread-coating composition, comprising preferably a polyurethane- or polyethylene-containing...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
W1971984277
Molecular Dynamics Simulation and Site-Directed Mutagenesis of Alcohol Acyltransferase: A Proposed Mechanism of Catalysis
Aroma in Vasconcellea pubescens fruit is determined by esters, which are the products of catalysis by alcohol acyltransferase (VpAAT1). VpAAT1 protein structure displayed the conserved HxxxD motif facing the solvent channel in the center of the structure. To gain insight into the role of these catalytic residues, kinet...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
2727430
Smart big data platform to offer evidence-based personalised support for healthy and independent living at home
It is a fact that the European population growth is slowing down, while the population ageing accelerates. Rapid increases in the elderly population are predicted for the coming decades due to the ageing of post-war baby births. Within Europe’s ageing population, Hearing Loss, Cardio Vascular Diseases, Cognitive Impair...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Computer Science and Informatics", "Systems and Communication Engineering" ]