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QA:1cb93956a7e3d3c9efe628b8
QAG:437b80a0bf8f1d44b6eda37c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Thus, CX3CR1 expression was associated with the aggressiveness of human colon cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b8d14066cb4612879bfb8ac8","quotes":["Thus, CX3CR1 expression is associated with the aggressiveness of human colon...
[ "CLM:b8d14066cb4612879bfb8ac8", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC4176124" ]
[ "SPAN:8e34798043cbbfe2742324bd" ]
[]
[]
{"qa_id":"QA:1cb93956a7e3d3c9efe628b8","qa_group_id":"QAG:437b80a0bf8f1d44b6eda37c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Thus, CX3CR1 expression was associated with the aggressiveness of ...
QA:1d0030803a63f1cbe69472cc
QAG:b8a148c4a4a188ef6d2be072
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In this research, surgical resection of CRC resulted in a decline in serum MIC-1 and the decreased serum MIC-1 was increased at the presence of tumor recurrence"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requir...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e85630c8af4ebc1864a3fbda","quotes":["In this research, surgical resection of CRC resulted in a decline in serum M...
[ "CLM:e85630c8af4ebc1864a3fbda", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC5421897" ]
[ "SPAN:64204cc4078a77527b894a48" ]
[]
[]
{"qa_id":"QA:1d0030803a63f1cbe69472cc","qa_group_id":"QAG:b8a148c4a4a188ef6d2be072","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In this research, surgical resection of CRC resulted in a decline ...
QA:1d06a3027c40cb2988fa089e
QAG:cd4dca8cd6635db3d24c4e30
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "These differences are mainly due to the early increased concentrations of MIC-1 in stage I and II, and with no significant difference between stages III and IV"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance require...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c30b2042fa9a969cd3e3c53d","quotes":["These differences are mainly due to the early elevated concentrations of MIC...
[ "CLM:c30b2042fa9a969cd3e3c53d", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC5421897" ]
[ "SPAN:365b3309a93c54bab8814c55", "SPAN:3d82c63e8c8efe4afda98087" ]
[]
[]
{"qa_id":"QA:1d06a3027c40cb2988fa089e","qa_group_id":"QAG:cd4dca8cd6635db3d24c4e30","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"These differences are mainly due to the early increased concentrat...
QA:1e9acf810800db3ce730d3be
QAG:bcc4aba951d7cd5aec0253ff
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "We observed that serum from CRC patients exhibited increased expression of miR-934 compared to that from the control group (Additional file 2 : Fig. S2B)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements:...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ffe75532a4aa457dc3a23072","quotes":["We observed that serum from CRC patients exhibited elevated expression of mi...
[ "CLM:ffe75532a4aa457dc3a23072", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:607899965b5dd46e4ba7112a" ]
[]
[]
{"qa_id":"QA:1e9acf810800db3ce730d3be","qa_group_id":"QAG:bcc4aba951d7cd5aec0253ff","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"We observed that serum from CRC patients exhibited increased expre...
QA:2113f85a15b2050b8a16e0e8
QAG:3702d96dd6629bd808a48ce1
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The number of Mo-MDSCs in the blood of CRC patients was also increased in CRC patients with short-term recurrence compared with those without recurrence (Fig. 7C )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance req...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:61be756da5cc1e05c48bac8c","quotes":["The number of Mo-MDSCs in the blood of CRC patients was also increased in CR...
[ "CLM:61be756da5cc1e05c48bac8c", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8119947" ]
[ "SPAN:f66042fb59ae6dcd5988839f" ]
[]
[]
{"qa_id":"QA:2113f85a15b2050b8a16e0e8","qa_group_id":"QAG:3702d96dd6629bd808a48ce1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The number of Mo-MDSCs in the blood of CRC patients was also incre...
QA:231582cc666d332b6f8dc02a
QAG:4acf260bc7a4dcd0187b44b7
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "4 P-STAT3 is required for S1PR1 promoted tumor growth and liver metastasis in CRC. a S1PR1 and p-STAT3 protein expression levels in SW480-exS1PR1 cells transduced with lenti-shSTAT3, as revealed using Western blotting. b STAT3 knockdown significantly inhibited the grow...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1ae2cd93da5f2c73fef0a7c6","quotes":["Fig. 4 P-STAT3 is required for S1PR1-promoted tumor growth and liver metasta...
[ "CLM:1ae2cd93da5f2c73fef0a7c6", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC6751205" ]
[ "SPAN:475f87c72c637abdf96962e9" ]
[]
[]
{"qa_id":"QA:231582cc666d332b6f8dc02a","qa_group_id":"QAG:4acf260bc7a4dcd0187b44b7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"4 P-STAT3 is required for S1PR1 promoted tumor growth and liver me...
QA:240d730fdb6a3dc38e6b996d
QAG:17b2ed19a56341d7c8091b64
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Interleukin-17 promoted neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7795cac80522afb92a0dc44d","quotes":["11. Zhang, Y. et al. Interleukin-17-induced neutrophil extracellular traps m...
[ "CLM:7795cac80522afb92a0dc44d", "CLM:0012c5301a22fe572fa575f9" ]
[ "PMCID:PMC9705377" ]
[ "SPAN:d8990e6b4f17fe4094891e49" ]
[]
[]
{"qa_id":"QA:240d730fdb6a3dc38e6b996d","qa_group_id":"QAG:17b2ed19a56341d7c8091b64","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Interleukin-17 promoted neutrophil extracellular traps mediate res...
QA:2657a7f433c6668e4c5b8f12
QAG:cd16078a5defdbc8f15fb0fa
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The splenic tumor injection led to sudden CRC liver metastasis in BALB/c mice as mentioned earlier ( Fig. 1A )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:58612d812bebfe5210dca556","quotes":["The splenic tumor injection resulted in sudden CRC liver metastasis in BALB/...
[ "CLM:58612d812bebfe5210dca556", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC9289841" ]
[ "SPAN:0ecbd9658f102597456b7029" ]
[]
[]
{"qa_id":"QA:2657a7f433c6668e4c5b8f12","qa_group_id":"QAG:cd16078a5defdbc8f15fb0fa","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The splenic tumor injection led to sudden CRC liver metastasis in ...
QA:292e6a01c00c5e4cdd35db0c
QAG:398140f9b592a9a9bef7bc37
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Significance Using mouse models that recapitulate key genetic abnormalities accumulating during colorectal cancer (CRC) tumorigenesis, we report that chemically induced colitis promoted development of colon tumors that were largely resistant to anti-VEGF antibody treat...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aeec9c38e9f709963ba16829","quotes":["Significance Using mouse models that recapitulate key genetic abnormalities ...
[ "CLM:aeec9c38e9f709963ba16829", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7474657" ]
[ "SPAN:1d742714f1e0c752258fb620" ]
[]
[]
{"qa_id":"QA:292e6a01c00c5e4cdd35db0c","qa_group_id":"QAG:398140f9b592a9a9bef7bc37","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Significance Using mouse models that recapitulate key genetic abno...
QA:2ac212604bebb9eab6bf1320
QAG:a688b04e92538945c9b61da5
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "And in 20 patients with documented CRC recurrence, the level of serum MIC-1 were increased (median: 841.2 pg/mL vs 1747.0 pg/mL, mean + SD: 1017 + 832.1 pg/mL vs 1902 + 953.5 pg/mL; p<0.001)"? Return the original wording with paper, Claim, and Evidence Span references....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d7b610978a3d1500f467b55d","quotes":["And in 20 patients with documented CRC recurrence, the level of serum MIC-1 ...
[ "CLM:d7b610978a3d1500f467b55d", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC5421897" ]
[ "SPAN:ce63e1b488eda072e0bfcf14" ]
[]
[]
{"qa_id":"QA:2ac212604bebb9eab6bf1320","qa_group_id":"QAG:a688b04e92538945c9b61da5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"And in 20 patients with documented CRC recurrence, the level of se...
QA:2afbaa5f7b2a75965aaabf9c
QAG:b1929e03c7e5d6225617bbca
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "the MWA group, which received MWA and an isotype control antibody; the TIGIT group, which was treated with anti-TIGIT; and the MWA plus TIGIT group, which was treated with MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6d69a1cd8e5f1a4ef2ed28b9","quotes":["Mice with MC38 colon cancer mice were divided into four groups: the control ...
[ "CLM:6d69a1cd8e5f1a4ef2ed28b9", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:10ad293173c9e8cb099e8c12" ]
[]
[]
{"qa_id":"QA:2afbaa5f7b2a75965aaabf9c","qa_group_id":"QAG:b1929e03c7e5d6225617bbca","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"the MWA group, which received MWA and an isotype control antibody;...
QA:2b78409b4842e408de25627b
QAG:38f6ce09b7f049038da366a1
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "25 reported that suppression of MGP or oxaliplatin treatment alone inhibited tumor growth in a CRC mouse model"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:88615042cfadd95b8d67ba7c","quotes":["Huang et al. 25 reported that suppression of MGP or oxaliplatin treatment al...
[ "CLM:88615042cfadd95b8d67ba7c", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:9d59b20e7910f606951a97b8" ]
[]
[]
{"qa_id":"QA:2b78409b4842e408de25627b","qa_group_id":"QAG:38f6ce09b7f049038da366a1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"25 reported that suppression of MGP or oxaliplatin treatment alone...
QA:2b7a65b5004e7cae19625222
QAG:5f4dc13fa67a307253e9142b
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "We found in vivo experiments that the activation of STING inhibited CRC liver metastasis in model mice and affected the macrophage phenotype in the tumor microenvironment"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provena...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1700423d4852d5cc4d6ae0d7","quotes":["We found in vivo experiments that the activation of STING inhibited CRC live...
[ "CLM:1700423d4852d5cc4d6ae0d7", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC10405073" ]
[ "SPAN:81709bc33b48d5af1b4f384d" ]
[]
[]
{"qa_id":"QA:2b7a65b5004e7cae19625222","qa_group_id":"QAG:5f4dc13fa67a307253e9142b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"We found in vivo experiments that the activation of STING inhibite...
QA:2c1a4d956510240d70188e17
QAG:a6f7de1f57dd20af52a4dc0e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "24 demonstrated that MGP promoted colon cancer cell proliferation by activating the NF-κB pathway through upregulation of the calcium signaling pathway, and the potential correlation between MGP and the tumor microenvironment was improved by using PD-L1 as an intermedi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a8af5ced7899cf5ac4863567","quotes":["Li et al. 24 demonstrated that MGP promoted colon cancer cell proliferation ...
[ "CLM:a8af5ced7899cf5ac4863567", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:655f9290a733cb8520c27068" ]
[]
[]
{"qa_id":"QA:2c1a4d956510240d70188e17","qa_group_id":"QAG:a6f7de1f57dd20af52a4dc0e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"24 demonstrated that MGP promoted colon cancer cell proliferation ...
QA:2d34881a3a43bc9facccc613
QAG:f1102fae070fdce88d902e45
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Conditional knockout of SHP-2 in TEMs and the deletion of the SHP-2 promoted the activation or phosphorylation of the Ang/Tie2-PI3K/Akt/mTOR pathway in TEMs, thereby enhancing down-stream proangiogenic factor: COX-2, VEGF, MMP-2/-9 and resulting into the tumor microang...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2dae3fa62a6bfc201323451a","quotes":["Conditional knockout of SHP-2 in TEMs and the delet...
[ "CLM:2dae3fa62a6bfc201323451a", "CLM:71ac756b9724a4423f9240ec", "CLM:7eeff011d0f24e24ba23357f" ]
[ "PMCID:PMC10207961", "PMCID:PMC10519095" ]
[ "SPAN:d7f2cd4ae6fe0e1b9d613e48", "SPAN:c19f9e0365ec4beb5e873993" ]
[ "ASC2:926ee447b3d880d996afc6d7" ]
[ "HYP:DCH:5c1545c69b6860146cf5f1e7" ]
{"qa_id":"QA:2d34881a3a43bc9facccc613","qa_group_id":"QAG:f1102fae070fdce88d902e45","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Conditional knockout of SHP-2 in TEMs and the deletion of the SHP-...
QA:2e247e8e3c6ed1cb804cbee0
QAG:8adb58a65fbecbcc7f4518b8
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "the TIGIT group, which received anti-TIGIT; and the MWA plus TIGIT group, which was treated with MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage w...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1e31f1086237bed25315d318","quotes":["Mice with MC38 colon cancer were divided into four groups as follows: the co...
[ "CLM:1e31f1086237bed25315d318", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:136a8bd68a3701f90147967f" ]
[]
[]
{"qa_id":"QA:2e247e8e3c6ed1cb804cbee0","qa_group_id":"QAG:8adb58a65fbecbcc7f4518b8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"the TIGIT group, which received anti-TIGIT; and the MWA plus TIGIT...
QA:2eb07d68bb5ebb7e7b304e66
QAG:9816cee03ae55b1320da6c73
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Moreover, analysis of CX3CR1 expression in primary tumors and formation of metastases revealed that patients who had advanced clinical stage disease, metastasis, or recurrent lesion within 3 years showed increased CX3CR1 expression in colon cancer tissue (Figure 1 A)"?...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fada1377a44c2b5caecc7275","quotes":["Moreover, analysis of CX3CR1 expression in primary tumors and formation of m...
[ "CLM:fada1377a44c2b5caecc7275", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC4176124" ]
[ "SPAN:631de293fcaa67102fb665e4" ]
[]
[]
{"qa_id":"QA:2eb07d68bb5ebb7e7b304e66","qa_group_id":"QAG:9816cee03ae55b1320da6c73","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Moreover, analysis of CX3CR1 expression in primary tumors and form...
QA:302e798e1a39f91df6bfd07d
QAG:063c88d72328fe830aea922b
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "A 34-year-old woman with metastatic MSI-H descending colon cancer, who had peritonitis due to perforation of primary tumor and received transverse colostomy, was enrolled (Patient 1)"? Return the original wording with paper, Claim, and Evidence Span references. Integr...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5ae6f51360966aa166baf4c5","quotes":["A 34-year-old woman with metastatic MSI-H descending colon cancer, who had p...
[ "CLM:5ae6f51360966aa166baf4c5", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC9705377" ]
[ "SPAN:c174613ecfae5b541be612e3" ]
[]
[]
{"qa_id":"QA:302e798e1a39f91df6bfd07d","qa_group_id":"QAG:063c88d72328fe830aea922b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"A 34-year-old woman with metastatic MSI-H descending colon cancer,...
QA:30f71f63da7d62420e3fffa8
QAG:b5e058526ab6b256d7bc1c74
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The tumor microenvironment (TME) represented a significant barrier to creating effective therapies for metastatic colorectal cancer (mCRC)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:232e07b7630a329252adb640","quotes":["The tumor microenvironment (TME) represents a signi...
[ "CLM:232e07b7630a329252adb640", "CLM:71ac756b9724a4423f9240ec", "CLM:5e3819a2807e080765297b28" ]
[ "PMCID:PMC6140580", "PMCID:PMC6598323" ]
[ "SPAN:1b92915e8ccd9b5884cedff1", "SPAN:707966fc77ae377d0f25dd3a" ]
[ "ASC2:c0a0736d25a8547ff3ebc599" ]
[ "HYP:DCH:f7c11766c97c567756d52b33" ]
{"qa_id":"QA:30f71f63da7d62420e3fffa8","qa_group_id":"QAG:b5e058526ab6b256d7bc1c74","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The tumor microenvironment (TME) represented a significant barrier...
QA:320d0ff77c7da9461cc70aae
QAG:aa8ea3c3e7042013c29b7ffe
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Conclusions Our findings proposed that immunosuppressive microenvironment in liver promoted by OXA enhanced liver metastasis of colorectal cancer, which highlighted a new consideration to balance the pro metastases and anti-cancer possibility of OXA treatment"? Return ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2b4c89596fe7c217a0741292","quotes":["Conclusions Our findings proposed that immunosuppressive microenvironment in...
[ "CLM:2b4c89596fe7c217a0741292", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC10494354" ]
[ "SPAN:d379856c6a38284a21f0a532" ]
[]
[]
{"qa_id":"QA:320d0ff77c7da9461cc70aae","qa_group_id":"QAG:aa8ea3c3e7042013c29b7ffe","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Conclusions Our findings proposed that immunosuppressive microenvi...
QA:32bd32c021c69cf671c82f0e
QAG:5e755fbf93d8159559b0d617
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "moreover, higher MGP mRNA expression was associated with a poorer prognosis and an overall survival of less than five years"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3c43895cacf66927900c3441","quotes":["Helena et al. 23 observed that MGP was overexpressed in CRC tumor mucosa at ...
[ "CLM:3c43895cacf66927900c3441", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:9e04444466101e07b1754e55" ]
[]
[]
{"qa_id":"QA:32bd32c021c69cf671c82f0e","qa_group_id":"QAG:5e755fbf93d8159559b0d617","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"moreover, higher MGP mRNA expression was associated with a poorer ...
QA:36b417f3642f506936ee8ce2
QAG:3d87e52580ce13ba2a7e0457
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Indeed, we found that Bv8/PROK2 levels was higher than CRC patients compared with age- matched healthy donors ( Fig. 4 A )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:28c09f715719fdb1d6c7311f","quotes":["Indeed, we found that Bv8/PROK2 levels were significantly higher in CRC pati...
[ "CLM:28c09f715719fdb1d6c7311f", "CLM:32074368e9eaad5d6640b1f3" ]
[ "PMCID:PMC7474657" ]
[ "SPAN:8a6d34ddcf080b150329ea54" ]
[]
[]
{"qa_id":"QA:36b417f3642f506936ee8ce2","qa_group_id":"QAG:3d87e52580ce13ba2a7e0457","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Indeed, we found that Bv8/PROK2 levels was higher than CRC patient...
QA:375c5b51551588bb172dc4ec
QAG:07b03351125b619406cffe3e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Recently, DNA damage has been associated with induction of CXCL10 as well as other proinflammatory genes, 27 while in pancreatic cancer ferroptosis promoted 8-OHdG formation led to STING activation"? Return the original wording with paper, Claim, and Evidence Span refe...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c058590685e853ad3df87c6f","quotes":["Recently, DNA damage has been associated with induction of CXCL10 as well as...
[ "CLM:c058590685e853ad3df87c6f", "CLM:0012c5301a22fe572fa575f9" ]
[ "PMCID:PMC10423492" ]
[ "SPAN:84dbcd15587fa3e97552ed60" ]
[]
[]
{"qa_id":"QA:375c5b51551588bb172dc4ec","qa_group_id":"QAG:07b03351125b619406cffe3e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Recently, DNA damage has been associated with induction of CXCL10 ...
QA:379ecb75f3799363aa9c516e
QAG:75edd5346e4a2a1a34fff264
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "To determine whether colon cancer cells could induce METs, macrophages were promoted with the CM from HCT116 cells for 12 hours at 37°C. METs were then visualized and assessment through SYTOX ® Green and IF staining as above described"? Return the original wording with...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4d26b093e9d96cfd8c6b6e3d","quotes":["To determine whether colon cancer cells could induce METs, macrophages were ...
[ "CLM:4d26b093e9d96cfd8c6b6e3d", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8671452" ]
[ "SPAN:5f385971b91e3a5b1562883c" ]
[]
[]
{"qa_id":"QA:379ecb75f3799363aa9c516e","qa_group_id":"QAG:75edd5346e4a2a1a34fff264","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To determine whether colon cancer cells could induce METs, macroph...
QA:37ddf2a43e3e84a056d3d8bd
QAG:813bef21889244fba93a21b3
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "22 Consistent with our results, Shimizu et al 23 found that IL-2 production was decreased in patients with CRC and hepatic metastasis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact su...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f147a85adc8f95ae514601a8","quotes":["22 Consistent with our results, Shimizu et al 23 found that IL-2 production ...
[ "CLM:f147a85adc8f95ae514601a8", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC6754330" ]
[ "SPAN:6c743c9b3a19c4a4a41cd328" ]
[]
[]
{"qa_id":"QA:37ddf2a43e3e84a056d3d8bd","qa_group_id":"QAG:813bef21889244fba93a21b3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"22 Consistent with our results, Shimizu et al 23 found that IL-2 p...
QA:37f8707629c56b57ababd660
QAG:b4d766806d38fdb68084f7fc
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Furthermore, CRC cell-derived exosomal miR-934 promoted M2 macrophage polarization via downregulation of PTEN expression and activation of the PI3K/AKT signaling pathway"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenan...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:999ddd2a4f9ab0d66b03210a","quotes":["In our study, we demonstrated that hnRNPA2B1 could mediate the packaging of ...
[ "CLM:999ddd2a4f9ab0d66b03210a", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:e842d58bcc48c6ecb8a8a542" ]
[]
[]
{"qa_id":"QA:37f8707629c56b57ababd660","qa_group_id":"QAG:b4d766806d38fdb68084f7fc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Furthermore, CRC cell-derived exosomal miR-934 promoted M2 macroph...
QA:3820e943843b20da6ae8d3bb
QAG:44604e9385a34351723df376
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Although the combination of surgery, chemotherapy, targeted therapy, and immunotherapy has partially improved the clinical efficacy of colorectal cancer (CRC) therapy, CRC still ranks third in terms of incidence and is the second leading cause of cancer-related deaths ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bb5ce98d9514f84d343ea9a9","quotes":["Although the combination of surgery, chemotherapy, targeted therapy, and imm...
[ "CLM:bb5ce98d9514f84d343ea9a9", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:d2010e5dfa0aff19645d9cca" ]
[]
[]
{"qa_id":"QA:3820e943843b20da6ae8d3bb","qa_group_id":"QAG:44604e9385a34351723df376","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Although the combination of surgery, chemotherapy, targeted therap...
QA:39913ad6050cd569ba32a711
QAG:a11d58a7fc66a1ef8de9ab78
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The results showed that the level of CCL7 in serum was higher than CRC patients with tumor metastasis or short-term recurrence than those without metastasis or recurrence (Fig. 7A, B )"? Return the original wording with paper, Claim, and Evidence Span references. Inte...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:96f5f5de54acee36327a07ae","quotes":["The results showed that the level of CCL7 in serum was significantly higher ...
[ "CLM:96f5f5de54acee36327a07ae", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC8119947" ]
[ "SPAN:57a157f929516ec8a492b36b" ]
[]
[]
{"qa_id":"QA:39913ad6050cd569ba32a711","qa_group_id":"QAG:a11d58a7fc66a1ef8de9ab78","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results showed that the level of CCL7 in serum was higher than...
QA:3ab7894f7130527cf68f9ec7
QAG:1596e9282cd14718b42e3a1d
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In this study, we found TCF4 expression and TAMs recruitment are increased in human CRC hepatic metastases compared with primary sites"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact s...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c8fd49ffe91a4db40e41b955","quotes":["In this study, we found TCF4 expression and TAMs recruitment are increased i...
[ "CLM:c8fd49ffe91a4db40e41b955", "CLM:3c9947cdb5135d5ca5bd3ac4" ]
[ "PMCID:PMC8476489" ]
[ "SPAN:f02433e1a908ce5e2e6ba8b7" ]
[]
[]
{"qa_id":"QA:3ab7894f7130527cf68f9ec7","qa_group_id":"QAG:1596e9282cd14718b42e3a1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In this study, we found TCF4 expression and TAMs recruitment are i...
QA:3b2367777b808ac96c4e5c91
QAG:cde77d1b1ee25c0ccf203f0a
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "To demonstrate this, a cohort of 62 MSI-H CRC patients who received PD-1 blockade therapy was retrospectively included (Table 1 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact suppor...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d48c609625847caf9b54d1c3","quotes":["To demonstrate this, a cohort of 62 MSI-H CRC patients who received PD-1 blo...
[ "CLM:d48c609625847caf9b54d1c3", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC9705377" ]
[ "SPAN:66eb11c4364785f6a738b473" ]
[]
[]
{"qa_id":"QA:3b2367777b808ac96c4e5c91","qa_group_id":"QAG:cde77d1b1ee25c0ccf203f0a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To demonstrate this, a cohort of 62 MSI-H CRC patients who receive...
QA:3b38de17dc3ac87d9e1b0e6b
QAG:87c2835face2e66e7bc01edd
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "a higher expression of MGP led to lower CD8 + T cell infiltration, and vice versa (Figure 1 I)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3aec66fca16345b72cd0198f","quotes":["Immunohistochemistry further indicated that MGP protein was overexpressed in...
[ "CLM:3aec66fca16345b72cd0198f", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:37cccceef7edfd5548adcdd8" ]
[]
[]
{"qa_id":"QA:3b38de17dc3ac87d9e1b0e6b","qa_group_id":"QAG:87c2835face2e66e7bc01edd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"a higher expression of MGP led to lower CD8 + T cell infiltration,...
QA:3b93a2cbae4d2ab154267d76
QAG:c0e35a0a675c4d985de0b342
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Notably, we observed that the expression level of STING was also decreased in metastatic foci compared to primary colorectal cancer foci ( Figure 1 A)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: re...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:944daec45453808408cd0b00","quotes":["Notably, we observed that the expression level of STING was also significant...
[ "CLM:944daec45453808408cd0b00", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC10405073" ]
[ "SPAN:b1ff87429456f26d4d5e9ea1" ]
[]
[]
{"qa_id":"QA:3b93a2cbae4d2ab154267d76","qa_group_id":"QAG:c0e35a0a675c4d985de0b342","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Notably, we observed that the expression level of STING was also d...
QA:3d73b53888c169bfa24415d7
QAG:908d2999413977eec3b3d373
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "I The CRC patients with high CHSY1 expression had decreased overall survival"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span ref...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:49d357c83164ea2bedf63e37","quotes":["I The CRC patients with high CHSY1 expression had reduced overall survival."...
[ "CLM:49d357c83164ea2bedf63e37", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC10519095" ]
[ "SPAN:3ee06c8e16bdeb95cb1867bc" ]
[]
[]
{"qa_id":"QA:3d73b53888c169bfa24415d7","qa_group_id":"QAG:908d2999413977eec3b3d373","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"I The CRC patients with high CHSY1 expression had decreased overal...
QA:3dab2eb10486bd8f2d86797f
QAG:9917eb184a687b7205689423
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Figure 6A ), suggesting that antitumor responses were increased in CT26-IL-9 tumors"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence S...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7859d9e2284a04b85d604872","quotes":["To further assess and confirm the antitumor effects of IL-9 in colon carcino...
[ "CLM:7859d9e2284a04b85d604872", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6598323" ]
[ "SPAN:1b6f5c5213888d01ed7d9935" ]
[]
[]
{"qa_id":"QA:3dab2eb10486bd8f2d86797f","qa_group_id":"QAG:9917eb184a687b7205689423","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Figure 6A ), suggesting that antitumor responses were increased in...
QA:3e2e647e06623d1db98aedcd
QAG:55f9c3891a48c9f40e06303c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In the present study, we demonstrated that the M2 polarization of macrophages promoted by CRC cell-derived exosomal miR-934 could promote CRLM via a CXCL13/CXCR5/NFκB/p65 positive feedback loop, which resulted in persistent crosstalk between tumor cells and TAMs, formi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:20cf83a763e71ae0dab1c311","quotes":["In the present study, we demonstrated that the M2 polarization of macrophage...
[ "CLM:20cf83a763e71ae0dab1c311", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:e36b9a63c885ac1afc20ae9d" ]
[]
[]
{"qa_id":"QA:3e2e647e06623d1db98aedcd","qa_group_id":"QAG:55f9c3891a48c9f40e06303c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In the present study, we demonstrated that the M2 polarization of ...
QA:3fcf8f4ad1802c2b8c88d77d
QAG:33cc80acff099ebc07b1f59b
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "b STAT3 knockdown inhibited the growth of SW480-exS1PR1 cells, as revealed using an MTT assay. c A wound healing assay showed STAT3 knockdown significantly inhibited the migration of SW480-exS1PR1 cells, 36 h after wounding. d A transwell assay showed STAT3 knockdown s...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b454457612f10f2693a4d979","quotes":["Fig. 4 P-STAT3 is required for S1PR1-promoted tumor growth and liver metasta...
[ "CLM:b454457612f10f2693a4d979", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6751205" ]
[ "SPAN:475f87c72c637abdf96962e9" ]
[]
[]
{"qa_id":"QA:3fcf8f4ad1802c2b8c88d77d","qa_group_id":"QAG:33cc80acff099ebc07b1f59b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"b STAT3 knockdown inhibited the growth of SW480-exS1PR1 cells, as ...
QA:405a2509c3089cbfb58c9d15
QAG:21fb4ef5e060c15f38435a3f
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "According to Kaplan–Meier survival curves, overall survival was decreased in patients with CRC and high CHSY1 expression (Fig. 1 I)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supp...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6085bb5833df94f4cfa4cc83","quotes":["According to Kaplan–Meier survival curves, overall survival was reduced in p...
[ "CLM:6085bb5833df94f4cfa4cc83", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC10519095" ]
[ "SPAN:75ec6605b637315609c2be59" ]
[]
[]
{"qa_id":"QA:405a2509c3089cbfb58c9d15","qa_group_id":"QAG:21fb4ef5e060c15f38435a3f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"According to Kaplan–Meier survival curves, overall survival was de...
QA:40dde5bc77cdb07d86901ec1
QAG:577b843c23d98ee087e66ae9
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Figure 2 AMPK α2 deficiency enhances tumour development of colon cancer cells in liver, which was associated with the more serious liver injury"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return th...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2bcd53b869551ecb73de7868","quotes":["Figure 2 AMPK α2 deficiency enhances tumour development of colon cancer cell...
[ "CLM:2bcd53b869551ecb73de7868", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC6378193" ]
[ "SPAN:4d6165f9fc1e318ad0d01f2c" ]
[]
[]
{"qa_id":"QA:40dde5bc77cdb07d86901ec1","qa_group_id":"QAG:577b843c23d98ee087e66ae9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Figure 2 AMPK α2 deficiency enhances tumour development of colon c...
QA:4171bdc333caf3ef0b58b9fc
QAG:70fb64bddc508a6639157359
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Mice with MC38 colon cancer were divided into four groups as follows: the control group, which received an isotype control antibody; the MWA group, which was treated with MWA and an isotype control antibody; the TIGIT group, which was treated with anti-TIGIT; and the M...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3bec563bcbc7ee4949a6764b","quotes":["Mice with MC38 colon cancer were divided into four groups as follows: the co...
[ "CLM:3bec563bcbc7ee4949a6764b", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:136a8bd68a3701f90147967f" ]
[]
[]
{"qa_id":"QA:4171bdc333caf3ef0b58b9fc","qa_group_id":"QAG:70fb64bddc508a6639157359","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Mice with MC38 colon cancer were divided into four groups as follo...
QA:45bebc7c6a8b520165434e2e
QAG:085226e11323531fd1c6661d
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The correlation analysis showed that miR-934 expression was associated with CXCL13 and CXCR5 expression both in primary CRC tissues and in paired liver metastatic tissues (Additional file 24 : Tables S9 and S10)"? Return the original wording with paper, Claim, and Evid...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a2e9a85861e916de6c3f147e","quotes":["The correlation analysis showed that miR-934 expression was positively assoc...
[ "CLM:a2e9a85861e916de6c3f147e", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:e82e385edb770adc6d9dd541" ]
[]
[]
{"qa_id":"QA:45bebc7c6a8b520165434e2e","qa_group_id":"QAG:085226e11323531fd1c6661d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The correlation analysis showed that miR-934 expression was associ...
QA:46e8c42371c32e06643bde06
QAG:d17263ce49d7f6bbb927f23c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "36 Changes in the liver microenvironment promoted by commensal microbes could be beneficial for patients suffering from CRC liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the e...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e900248356fa89bd3e6b56d2","quotes":["36 Changes in the liver microenvironment induced by commensal microbes could...
[ "CLM:e900248356fa89bd3e6b56d2", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC9289841" ]
[ "SPAN:f2e362dda72815f814daa4e7" ]
[]
[]
{"qa_id":"QA:46e8c42371c32e06643bde06","qa_group_id":"QAG:d17263ce49d7f6bbb927f23c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"36 Changes in the liver microenvironment promoted by commensal mic...
QA:48d7f293dce7e2752db580dd
QAG:9653eeb61f1e5a8673f370fb
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In conclusion, liver metastasis of CRC was associated with an increase in the number of CD4 + FOXP3 + Tregs and upregulation of the HGF/c-Met signaling pathway, indicating the presence of potential novel therapeutic targets for liver metastasis"? Return the original wo...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9cecb57e03121a0767d14994","quotes":["In conclusion, liver metastasis of CRC is associate...
[ "CLM:9cecb57e03121a0767d14994", "CLM:71ac756b9724a4423f9240ec", "CLM:fb5daaeff9e0fd119348fbb9" ]
[ "PMCID:PMC7400973", "PMCID:PMC10519095" ]
[ "SPAN:194fce9b14874ef3381020ee", "SPAN:7dda229dc761c69a6e03f429" ]
[ "ASC2:c319c1f2332bf19ecd13e613" ]
[ "HYP:DCH:2494a3048fdaa12124f0ec31" ]
{"qa_id":"QA:48d7f293dce7e2752db580dd","qa_group_id":"QAG:9653eeb61f1e5a8673f370fb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In conclusion, liver metastasis of CRC was associated with an incr...
QA:48e289f274b252d09412db8e
QAG:88e5d990fe69a1f03aa72910
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "a Sequences of the predicted binding sites between miR-934 and the 3′-UTR of the wild-type (WT)/mutant (MUT) PTEN gene. b A luciferase reporter gene activity assay was performed to determine the effects of miR-934 mimics or anti-miR-934 on the luciferase activity of th...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e47ca56580adc400051f16d1","quotes":["Fig. 5 Exosomal miR-934 induces M2 macrophage polarization via downregulatio...
[ "CLM:e47ca56580adc400051f16d1", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:8778dd8c5a506ff757bd2cc9" ]
[]
[]
{"qa_id":"QA:48e289f274b252d09412db8e","qa_group_id":"QAG:88e5d990fe69a1f03aa72910","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"a Sequences of the predicted binding sites between miR-934 and the...
QA:49bdcceaa14f2593680927ab
QAG:18efb94f6786848aeb8933e0
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Our study showed that increased CX3CR1 expression was correlated with the poor prognosis in human colon carcinoma"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage wit...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:543e9a075b4329b83de13435","quotes":["Our study showed that enhanced CX3CR1 expression was correlated with the poo...
[ "CLM:543e9a075b4329b83de13435", "CLM:3c9947cdb5135d5ca5bd3ac4" ]
[ "PMCID:PMC4176124" ]
[ "SPAN:8dd4fbc5d794a5d4dd6cfb08" ]
[]
[]
{"qa_id":"QA:49bdcceaa14f2593680927ab","qa_group_id":"QAG:18efb94f6786848aeb8933e0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our study showed that increased CX3CR1 expression was correlated w...
QA:4a0b266b47ba3c3f23c9ce05
QAG:d96ed080c634856e11444e3c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Interestingly, a recent in vitro study found that IL-10 blockade in organotypic slides from patients with metastatic CRC increased activated CD8+ frequency and enhanced the activation and cytotoxicity of CAR-T cells, leading to higher cancer cell apoptosis"? Return the...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8f46d77ceb0e60c55518d13d","quotes":["Interestingly, a recent in vitro study found that I...
[ "CLM:8f46d77ceb0e60c55518d13d", "CLM:32074368e9eaad5d6640b1f3", "CLM:0a738d052dc087fde9e46f08" ]
[ "PMCID:PMC10964083", "PMCID:PMC7678301" ]
[ "SPAN:8795903c20b78c766b434545", "SPAN:3f5496e55b250536878ab070" ]
[ "ASC2:94978fef6938243617b8ef57" ]
[ "HYP:DCH:50d933354ec6bcc16a0947f2" ]
{"qa_id":"QA:4a0b266b47ba3c3f23c9ce05","qa_group_id":"QAG:d96ed080c634856e11444e3c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Interestingly, a recent in vitro study found that IL-10 blockade i...
QA:4a5074b8614d2f9098cb1694
QAG:64c460d6a5c8b9cf97d72fb5
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Here we report that mCRC expression of the chemokine CCL2 enabled recruitment of CCR2 + IM from the bone marrow to the peripheral blood"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4dcb3ff8cb620a67e31ef832","quotes":["Here we report that mCRC expression of the chemokine CCL2 facilitates recrui...
[ "CLM:4dcb3ff8cb620a67e31ef832", "CLM:04bbc50258758972aa54295d" ]
[ "PMCID:PMC6140580" ]
[ "SPAN:800236dc949ad276b52e37ca" ]
[]
[]
{"qa_id":"QA:4a5074b8614d2f9098cb1694","qa_group_id":"QAG:64c460d6a5c8b9cf97d72fb5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Here we report that mCRC expression of the chemokine CCL2 enabled ...
QA:4daf446a7efe038cc2ada12f
QAG:cdc40c6367e4ff6b9a2bdfbe
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The above data indicate that aberrantly high expression of miR-934 was associated with tumor progression and liver metastasis in CRC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact sup...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:323fec5e98f83750c462dd03","quotes":["The above data indicate that aberrantly high expression of miR-934 is signif...
[ "CLM:323fec5e98f83750c462dd03", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:ee2a82a615fbea407e282c3d" ]
[]
[]
{"qa_id":"QA:4daf446a7efe038cc2ada12f","qa_group_id":"QAG:cdc40c6367e4ff6b9a2bdfbe","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The above data indicate that aberrantly high expression of miR-934...
QA:4e767e4b856616be5aeee187
QAG:abbf854338b6c26700fe3b0d
provenance_qa
paper_evidence_availability
provenance_qa
G013
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7034239? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC7034239","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC7034239" ]
[]
[]
[]
{"qa_id":"QA:4e767e4b856616be5aeee187","qa_group_id":"QAG:abbf854338b6c26700fe3b0d","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G013","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7034239...
QA:4fc8b123d60f17c3cc461f44
QAG:00a5b12d18504f82ca672822
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Using a murine model of mCRC that recapitulates these findings from human disease, we show that targeting CCR2 decreased TAM accumulation in liver metastasis and restores anti-tumor immunity"? Return the original wording with paper, Claim, and Evidence Span references....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7ad62afcf486e0e3f7c5bc55","quotes":["Using a murine model of mCRC that recapitulates these findings from human di...
[ "CLM:7ad62afcf486e0e3f7c5bc55", "CLM:04bbc50258758972aa54295d" ]
[ "PMCID:PMC6140580" ]
[ "SPAN:180634ccb7c5f123707d69b9" ]
[]
[]
{"qa_id":"QA:4fc8b123d60f17c3cc461f44","qa_group_id":"QAG:00a5b12d18504f82ca672822","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Using a murine model of mCRC that recapitulates these findings fro...
QA:4fe8ccb16db05de92cefb269
QAG:860d9dd19f6df26201bfda27
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "and the MWA plus TIGIT group, which received MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; asse...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0956beeb5c637a6f28998add","quotes":["Mice with MC38 colon cancer mice were divided into four groups: the control ...
[ "CLM:0956beeb5c637a6f28998add", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:10ad293173c9e8cb099e8c12" ]
[]
[]
{"qa_id":"QA:4fe8ccb16db05de92cefb269","qa_group_id":"QAG:860d9dd19f6df26201bfda27","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"and the MWA plus TIGIT group, which received MWA and anti-TIGIT\"?...
QA:5084ea7755060f5853d9cefb
QAG:254f700b5e3675dac25451d6
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "33 , 34 Our previous results also suggested that colon cancer liver metastasis led to liver injury"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim,...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:051cd788c46ea53bc5eac1db","quotes":["33 , 34 Our previous results also suggested that colon cancer liver metastas...
[ "CLM:051cd788c46ea53bc5eac1db", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC6378193" ]
[ "SPAN:6c6afe44ae93bb43568f91bb" ]
[]
[]
{"qa_id":"QA:5084ea7755060f5853d9cefb","qa_group_id":"QAG:254f700b5e3675dac25451d6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"33 , 34 Our previous results also suggested that colon cancer live...
QA:52681bf9a6e0f26087eba81f
QAG:f1a8780f7b435228e848fce4
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Although Huang et al found decreased IL-9 levels in colon carcinoma tissues and an association with colon cancer progression, 26 they only evaluated tissue IL-9 expression by immunohistochemistry, a semi-quantitative technique, and did not evaluate the association of I...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f744e858ab777b9d4a47c30f","quotes":["Although Huang et al found reduced IL-9 levels in colon carcinoma tissues an...
[ "CLM:f744e858ab777b9d4a47c30f", "CLM:32074368e9eaad5d6640b1f3" ]
[ "PMCID:PMC6598323" ]
[ "SPAN:5a452c745f858b7e60121b43" ]
[]
[]
{"qa_id":"QA:52681bf9a6e0f26087eba81f","qa_group_id":"QAG:f1a8780f7b435228e848fce4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Although Huang et al found decreased IL-9 levels in colon carcinom...
QA:5501b78dc24adae380e47f66
QAG:528a44a426b1f62c65eaf818
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In addition, HGF and c-Met are upregulated in a number of cancer types, including CRC ( 27 ), and was associated with tumor recurrence and an unfavorable patient prognosis ( 28 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:836e978181a196f940096743","quotes":["In addition, HGF and c-Met are upregulated in a number of cancer types, incl...
[ "CLM:836e978181a196f940096743", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7400973" ]
[ "SPAN:5b125b473379d64654a55942" ]
[]
[]
{"qa_id":"QA:5501b78dc24adae380e47f66","qa_group_id":"QAG:528a44a426b1f62c65eaf818","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In addition, HGF and c-Met are upregulated in a number of cancer t...
QA:5686ea519c0c09e67b72a5e8
QAG:75fa617ec7e0f7af6150b7d9
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In conclusion, CD4 + FOXP3 + Treg levels increased and the HGF/c-Met pathway was upregulated during the liver metastasis of CRC in mice, indicating the presence of potential therapeutic targets"? Return the original wording with paper, Claim, and Evidence Span referenc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ef3aeb79e5ab571f9413bd46","quotes":["In conclusion, CD4 + FOXP3 + Treg levels increased and the HGF/c-Met pathway...
[ "CLM:ef3aeb79e5ab571f9413bd46", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC7400973" ]
[ "SPAN:a0705a93577e65c3880ea644" ]
[]
[]
{"qa_id":"QA:5686ea519c0c09e67b72a5e8","qa_group_id":"QAG:75fa617ec7e0f7af6150b7d9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In conclusion, CD4 + FOXP3 + Treg levels increased and the HGF/c-M...
QA:590189abea41b48755e3dfa5
QAG:858a5866d608534d6fc4b360
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Vancomycin promoted the CRC liver metastases (p=0.028) while colistin inhibited the CRC liver metastases (p=0.041)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage wi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a8175c6437b0917c7b28653e","quotes":["Vancomycin promoted the CRC liver metastases (p=0.028) while colistin inhibi...
[ "CLM:a8175c6437b0917c7b28653e", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC9289841" ]
[ "SPAN:e7283f7de514c77987a7a1f6" ]
[]
[]
{"qa_id":"QA:590189abea41b48755e3dfa5","qa_group_id":"QAG:858a5866d608534d6fc4b360","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Vancomycin promoted the CRC liver metastases (p=0.028) while colis...
QA:5903e547a30cd56158753afb
QAG:4e803b0701f2522a2adf2888
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Moreover, we provide evidence that recruitment of these Tie2+ macrophages to the colon tumors can be inhibited by anti-PD-L1 and dual immune checkpoint blockade which further underlines their supportive role in metastasis of the colon cancer cells to the liver"? Return...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6e6d7a9c435213f908017e6c","quotes":["Moreover, we provide evidence that recruitment of t...
[ "CLM:6e6d7a9c435213f908017e6c", "CLM:97ab2e5fc9dad87b35fc26cd", "CLM:1919a6ca1fd65c9cd4e9bf97" ]
[ "PMCID:PMC6700499", "PMCID:PMC10207961" ]
[ "SPAN:8d178a1eb3b0d3b2053aac0b", "SPAN:752a5402c5fadc5da0b989a2" ]
[ "ASC2:103e73cd48ad2fbb8f982f57" ]
[]
{"qa_id":"QA:5903e547a30cd56158753afb","qa_group_id":"QAG:4e803b0701f2522a2adf2888","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Moreover, we provide evidence that recruitment of these Tie2+ macr...
QA:5c37fd9b6f06978cd18fdc86
QAG:4454218a78c7f4f0f7975e6d
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The results revealed that Treg lymphocytes were increased in the F. nucleatum group as compared to that in the PBS-administered group ( Figure 4F ), which corroborates with the tumor promoting role of Tregs in CRC progression"? Return the original wording with paper, C...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a32b0032cc822202c31f4855","quotes":["The results revealed that Treg lymphocytes were significantly elevated in th...
[ "CLM:a32b0032cc822202c31f4855", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8908934" ]
[ "SPAN:e2ce74027742a4c1ad8aee6b" ]
[]
[]
{"qa_id":"QA:5c37fd9b6f06978cd18fdc86","qa_group_id":"QAG:4454218a78c7f4f0f7975e6d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results revealed that Treg lymphocytes were increased in the F...
QA:5c8ca88b64bf1c5b89a2a684
QAG:396091012c1c96e8ce631300
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In China, CRC incidence has increased constantly during the past decades and the mortality rate of CRC is currently ranked the fifth among all cancers"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: re...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:171f05e4a1ee6e989b4a80d5","quotes":["In China, CRC incidence has increased constantly during the past decades and...
[ "CLM:171f05e4a1ee6e989b4a80d5", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6477719" ]
[ "SPAN:afcdbbd70d74b52d1bfb1b67" ]
[]
[]
{"qa_id":"QA:5c8ca88b64bf1c5b89a2a684","qa_group_id":"QAG:396091012c1c96e8ce631300","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In China, CRC incidence has increased constantly during the past d...
QA:5ccc93c2857fa3efb730e4ae
QAG:c6a8bf05f71ad9d20ffd1c56
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "39 In in vivo experiments with OI, the survival cycle of mice treated with relatively low doses of OI in a colorectal cancer liver metastasis model was decreased thus preventing the simultaneous collection of the required experimental data"? Return the original wording...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7ffea46e1298fcd9ef5ef584","quotes":["39 In in vivo experiments with OI, the survival cycle of mice treated with r...
[ "CLM:7ffea46e1298fcd9ef5ef584", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC10405073" ]
[ "SPAN:a8bb9ee965ea206ab6dbf49a" ]
[]
[]
{"qa_id":"QA:5ccc93c2857fa3efb730e4ae","qa_group_id":"QAG:c6a8bf05f71ad9d20ffd1c56","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"39 In in vivo experiments with OI, the survival cycle of mice trea...
QA:5d395c5a44743134eae584fc
QAG:9df29387e246d3fbfda97d1c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In this study, we revealed that MGP expression was higher than CRC tissues than that in paracancerous tissues"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5b527b33ce1c631236e702a7","quotes":["In this study, we revealed that MGP expression was higher in CRC tissues tha...
[ "CLM:5b527b33ce1c631236e702a7", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:f95447789268d5aaf2c3e965" ]
[]
[]
{"qa_id":"QA:5d395c5a44743134eae584fc","qa_group_id":"QAG:9df29387e246d3fbfda97d1c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In this study, we revealed that MGP expression was higher than CRC...
QA:5db1a63ac0d1e36f0887b961
QAG:f6186dc039698d49b34ac041
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Our study showed that enhanced CX3CR1 expression was correlated with the poor prognosis in human colon carcinoma"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2a9ed573176ba8407d79eae2","quotes":["Our study showed that enhanced CX3CR1 expression was correlated with the poo...
[ "CLM:2a9ed573176ba8407d79eae2", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC4176124" ]
[ "SPAN:8dd4fbc5d794a5d4dd6cfb08" ]
[]
[]
{"qa_id":"QA:5db1a63ac0d1e36f0887b961","qa_group_id":"QAG:f6186dc039698d49b34ac041","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our study showed that enhanced CX3CR1 expression was correlated wi...
QA:5dec5667dacee0e393dfe832
QAG:b6502c6e9410604960eb05ee
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Recently, DNA damage has been associated with induction of CXCL10 as well as other proinflammatory genes, 27 while in pancreatic cancer ferroptosis-induced 8-OHdG formation led to STING activation"? Return the original wording with paper, Claim, and Evidence Span refer...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f8a9cbd9af1162d707b12f34","quotes":["Recently, DNA damage has been associated with induction of CXCL10 as well as...
[ "CLM:f8a9cbd9af1162d707b12f34", "CLM:0012c5301a22fe572fa575f9" ]
[ "PMCID:PMC10423492" ]
[ "SPAN:84dbcd15587fa3e97552ed60" ]
[]
[]
{"qa_id":"QA:5dec5667dacee0e393dfe832","qa_group_id":"QAG:b6502c6e9410604960eb05ee","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Recently, DNA damage has been associated with induction of CXCL10 ...
QA:61d354257c1613b4159343a3
QAG:a359186a5512c4ab2c25cbfb
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "have confirmed that decreased Th17 infiltration was associated with CRC progression in patients , which is in agreement with our findings"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exac...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f925f7472cd4697adeb47b25","quotes":["Ling et al. have confirmed that decreased Th17 infiltration is associated wi...
[ "CLM:f925f7472cd4697adeb47b25", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8908934" ]
[ "SPAN:480cd153a97b6ac96e16a4d7" ]
[]
[]
{"qa_id":"QA:61d354257c1613b4159343a3","qa_group_id":"QAG:a359186a5512c4ab2c25cbfb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"have confirmed that decreased Th17 infiltration was associated wit...
QA:628bb2bd114e582ed99b9419
QAG:985257836efd3ef8f33ad16f
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "vulgatus affected CRC liver metastasis in vivo , we determined whether the proliferation of KCs was promoted by B. vulgatus"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:60156f0e38e094faae13d7bc","quotes":["CFU, colony-forming unit. *p<0.05, † p<0.01. Considering that B. vulgatus af...
[ "CLM:60156f0e38e094faae13d7bc", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC9289841" ]
[ "SPAN:3e1f52b1032b268f92cec121" ]
[]
[]
{"qa_id":"QA:628bb2bd114e582ed99b9419","qa_group_id":"QAG:985257836efd3ef8f33ad16f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"vulgatus affected CRC liver metastasis in vivo , we determined whe...
QA:6339f71426d6964ded73a24f
QAG:395753c6016096b659d54971
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "However, the prognosis of patients with metastatic CRC (mCRC) who have received postoperative adjuvant chemoradiotherapy and radiofrequency therapy is still poor, with a 5-year overall survival (OS) rate less than 15%, which is the main challenge for CRC treatment at p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:21f4432ebbcd1f8d6ef9524e","quotes":["However, the prognosis of patients with metastatic CRC (mCRC) who have recei...
[ "CLM:21f4432ebbcd1f8d6ef9524e", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC8671452" ]
[ "SPAN:8c9cf76a55037a9993b3caca" ]
[]
[]
{"qa_id":"QA:6339f71426d6964ded73a24f","qa_group_id":"QAG:395753c6016096b659d54971","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"However, the prognosis of patients with metastatic CRC (mCRC) who ...
QA:66af57d8046c39003d44ebb4
QAG:d1ec4c7175cb803c985f15b4
provenance_qa
paper_evidence_availability
provenance_qa
G013
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:23081697? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:23081697","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:23081697" ]
[]
[]
[]
{"qa_id":"QA:66af57d8046c39003d44ebb4","qa_group_id":"QAG:d1ec4c7175cb803c985f15b4","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G013","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:23081697? E...
QA:66ef48e3964df3993dc5c34d
QAG:6c02c129a41521a0ba68e599
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Collectively, these results suggest that F4/80 + IL-12 + cells promoted by OGNV-miR-18a plays a crucial role in the inhibition of liver metastasis of colon cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3450f2f545328d62ada5aeda","quotes":["Collectively, these results suggest that F4/80 + IL-12 + cells induced by OG...
[ "CLM:3450f2f545328d62ada5aeda", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC5041936" ]
[ "SPAN:0c4faf1ee58cbe9ba7318f09" ]
[]
[]
{"qa_id":"QA:66ef48e3964df3993dc5c34d","qa_group_id":"QAG:6c02c129a41521a0ba68e599","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Collectively, these results suggest that F4/80 + IL-12 + cells pro...
QA:687cb7076536adef1bb0bba2
QAG:62308caa65c4c9d94ab61d9e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "0001 Since human samples and cellular experiments cannot adequately simulate the tumor microenvironment, we demonstrated in vivo that CHSY1 promoted CD8 + T cell exhaustion and liver metastasis from CRC"? Return the original wording with paper, Claim, and Evidence Span...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0012c5301a22fe572fa575f9","quotes":["C , D qRT-PCR and western blotting were performed t...
[ "CLM:0012c5301a22fe572fa575f9", "CLM:71ac756b9724a4423f9240ec", "CLM:8f46d77ceb0e60c55518d13d" ]
[ "PMCID:PMC10519095", "PMCID:PMC10964083" ]
[ "SPAN:cba42e0bb022e93f2c1abef2", "SPAN:8795903c20b78c766b434545" ]
[ "ASC2:55153f6930317c80e60e9ed8" ]
[ "HYP:DCH:88a224ab520358117fcfe672" ]
{"qa_id":"QA:687cb7076536adef1bb0bba2","qa_group_id":"QAG:62308caa65c4c9d94ab61d9e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"0001 Since human samples and cellular experiments cannot adequatel...
QA:6907967e9bc64d8519e26fea
QAG:ebf7c8388f7c371064b4a5ac
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In cases of pancreatic cancer liver metastases, significantly elevated levels of circulating SAA in patients was associated with reduced survival rates"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eb7b9e7cee38d9cddd922c73","quotes":["In cases of pancreatic cancer liver metastases, significantly elevated level...
[ "CLM:eb7b9e7cee38d9cddd922c73", "CLM:04bbc50258758972aa54295d" ]
[ "PMCID:PMC9926712" ]
[ "SPAN:01cb82b4bdc3e556d8103856" ]
[]
[]
{"qa_id":"QA:6907967e9bc64d8519e26fea","qa_group_id":"QAG:ebf7c8388f7c371064b4a5ac","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In cases of pancreatic cancer liver metastases, significantly elev...
QA:6a44200157e426a36158698b
QAG:45e30103fcbd39ef1864fc12
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The results showed that the level of CCL7 in serum was higher than CRC patients with tumor metastasis or short-term recurrence than those without metastasis or recurrence"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provena...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:986ef1e72a7649f43abb9787","quotes":["The results showed that the level of CCL7 in serum was significantly higher ...
[ "CLM:986ef1e72a7649f43abb9787", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC8119947" ]
[ "SPAN:b23acf03715d259a89b43e1f" ]
[]
[]
{"qa_id":"QA:6a44200157e426a36158698b","qa_group_id":"QAG:45e30103fcbd39ef1864fc12","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results showed that the level of CCL7 in serum was higher than...
QA:6bcacb8bcfea9bb8aeccd7ab
QAG:bb58093da4258d680b11fd0c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Furthermore, DMXAA did not improve the viability of CRC cancer cells in the presence of tumor cells alone ( Figure S1 C)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting pass...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:904199ec1e3ecde961ffaa3b","quotes":["Furthermore, DMXAA did not affect the viability of CRC cancer cells in the p...
[ "CLM:904199ec1e3ecde961ffaa3b", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC10405073" ]
[ "SPAN:76ec4c251438bf230763ae33" ]
[]
[]
{"qa_id":"QA:6bcacb8bcfea9bb8aeccd7ab","qa_group_id":"QAG:bb58093da4258d680b11fd0c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Furthermore, DMXAA did not improve the viability of CRC cancer cel...
QA:6c74063af3c4b5b19be30eb3
QAG:149eedc39ee00dffc5c2dc62
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "b S1PR1 overexpression significantly promoted the growth of SW480 and S1PR1 knockdown inhibited the growth of HCT116, as revealed using an MTT assay. c A wound healing assay showed S1PR1 overexpression significantly promoted cell migration of SW480 and S1PR1 knockdown ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8392ac406c0f7b438158aa41","quotes":["Fig. 2 S1PR1 promote CRC cell proliferation, invasion, migration and liver m...
[ "CLM:8392ac406c0f7b438158aa41", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6751205" ]
[ "SPAN:7a8eac19041000316563bf1a" ]
[]
[]
{"qa_id":"QA:6c74063af3c4b5b19be30eb3","qa_group_id":"QAG:149eedc39ee00dffc5c2dc62","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"b S1PR1 overexpression significantly promoted the growth of SW480 ...
QA:6d171b469a5b34d3dc290cf7
QAG:b440cab3847aea7d380275cd
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Another study demonstrated that the combination therapy of CCR2 inhibition and Folfirnox improved the outcome of pancreatic cancer in patients"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:97ab2e5fc9dad87b35fc26cd","quotes":["Another study demonstrated that the combination therapy of CCR2 inhibition a...
[ "CLM:97ab2e5fc9dad87b35fc26cd", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8476489" ]
[ "SPAN:8ca16a474ea38cc280e8646a" ]
[]
[]
{"qa_id":"QA:6d171b469a5b34d3dc290cf7","qa_group_id":"QAG:b440cab3847aea7d380275cd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Another study demonstrated that the combination therapy of CCR2 in...
QA:6e39d4f38b23f0cf59a0f97a
QAG:26c01ca7bc97293dbc11d2f3
provenance_qa
paper_evidence_availability
provenance_qa
G013
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6819206? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC6819206","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC6819206" ]
[]
[]
[]
{"qa_id":"QA:6e39d4f38b23f0cf59a0f97a","qa_group_id":"QAG:26c01ca7bc97293dbc11d2f3","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G013","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6819206...
QA:6e832ba8603dab4318cda84f
QAG:059170b212eb98695976c6a6
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Taken together, IL-9 protein and mRNA amounts were both markedly increased in adjacent normal tissue samples compared with colon cancer specimens, suggesting that IL-9 may exert antitumor effects in colon cancer"? Return the original wording with paper, Claim, and Evid...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3cbebc4056a010da77132261","quotes":["Taken together, IL-9 protein and mRNA amounts were both markedly elevated in...
[ "CLM:3cbebc4056a010da77132261", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6598323" ]
[ "SPAN:df8c4e27e6684675522c34f4" ]
[]
[]
{"qa_id":"QA:6e832ba8603dab4318cda84f","qa_group_id":"QAG:059170b212eb98695976c6a6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Taken together, IL-9 protein and mRNA amounts were both markedly i...
QA:7092477a31d869ab50264108
QAG:abad6236614ba60a1951d418
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "During the exploration of the underlying mechanisms of MDSCs involved in the regulation of CRC dormancy, we found that CCL7 secreted by Mo-MDSCs acted as an important role in the promotion of the proliferation of dormant HT29 cells promoted by MDSCs"? Return the origin...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d12b84ada4e170e0dd131836","quotes":["During the exploration of the underlying mechanisms of MDSCs involved in the...
[ "CLM:d12b84ada4e170e0dd131836", "CLM:32074368e9eaad5d6640b1f3" ]
[ "PMCID:PMC8119947" ]
[ "SPAN:cdfb51cd5c0283848a73af6d" ]
[]
[]
{"qa_id":"QA:7092477a31d869ab50264108","qa_group_id":"QAG:abad6236614ba60a1951d418","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"During the exploration of the underlying mechanisms of MDSCs invol...
QA:716fe0d3f114864f203aba39
QAG:dd711b4f0b9a04b9f3f7da4c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "To investigate whether increased S1PR1–STAT3 signaling in CRC cells would induce a production of factors that could prime distant premetastatic sites in the liver, we generated tumor conditioned media (TCM) from the MC38-exS1PR1 group and MC38-exControl group"? Return ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:18187e906c8c91f16aac59bf","quotes":["To investigate whether increased S1PR1–STAT3 signaling in CRC cells would in...
[ "CLM:18187e906c8c91f16aac59bf", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC6751205" ]
[ "SPAN:3fcea4434d0b73671b661077" ]
[]
[]
{"qa_id":"QA:716fe0d3f114864f203aba39","qa_group_id":"QAG:dd711b4f0b9a04b9f3f7da4c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To investigate whether increased S1PR1–STAT3 signaling in CRC cell...
QA:746656f09c15da9cad28b6d9
QAG:29e024769f433f3b3991c3fd
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Furthermore, in CRC liver metastasis mouse model, MGP expression in liver metastasis tissues was higher than that in normal liver tissues of eight C57BL/6 mice, as determined by western blotting ( Figure S1 ), consistent with the results of human samples. qRT-PCR and w...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:da0b4dffd67a5725ace73fc7","quotes":["Furthermore, in CRC liver metastasis mouse model, M...
[ "CLM:da0b4dffd67a5725ace73fc7", "CLM:7795cac80522afb92a0dc44d", "CLM:7daf8075eb6404f5979b04e5" ]
[ "PMCID:PMC8990480", "PMCID:PMC10492032" ]
[ "SPAN:3f323ef460118baf0ed7dea7", "SPAN:26ee743ad8376ccb599f57da" ]
[ "ASC2:88d6ba2dd9e9a2e697bb9eba" ]
[ "HYP:DCH:10e6a4799fae96f0d643f793" ]
{"qa_id":"QA:746656f09c15da9cad28b6d9","qa_group_id":"QAG:29e024769f433f3b3991c3fd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Furthermore, in CRC liver metastasis mouse model, MGP expression i...
QA:747b294206cb178e30167ad6
QAG:4ca3b7ad3df1f602a4774073
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "CCK8 and transwell migration assays showed that supernatants from MLRs containing HSCs promoted CT26 cell proliferation and migration, confirming that HSCs in hepatic microenvironments could induce CRC cell proliferation and migration"? Return the original wording with...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0680a63ec3f04feaab114cfc","quotes":["CCK8 and transwell migration assays showed that supernatants from MLRs conta...
[ "CLM:0680a63ec3f04feaab114cfc", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6754330" ]
[ "SPAN:39564d4c314ebca303cd52bb" ]
[]
[]
{"qa_id":"QA:747b294206cb178e30167ad6","qa_group_id":"QAG:4ca3b7ad3df1f602a4774073","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"CCK8 and transwell migration assays showed that supernatants from ...
QA:779acf43129a426a8d143c0f
QAG:0cde08afe4355748cde33a28
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Sole CTLA-4 and PD-L1 inhibition only moderately decreased metastatic spread of the colon cancer cells, though CTLA-4 blockade being superior to PD-L1 inhibition"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:06ac56904fbab2322b5096d2","quotes":["Sole CTLA-4 and PD-L1 inhibition only moderately re...
[ "CLM:06ac56904fbab2322b5096d2", "CLM:0478df56bd5aa1173e674769", "CLM:2f18a10139e57fbed1497590", "CLM:f10b00e03249f6ce269e1eb0", "CLM:0012c5301a22fe572fa575f9" ]
[ "PMCID:PMC6700499", "PMCID:PMC10519095", "PMCID:PMC8990480" ]
[ "SPAN:c0c5cb5b1045c15be72b7400", "SPAN:7f4de2ae1e00288fea01f48f", "SPAN:84bf9aff324fa321ccc4186e", "SPAN:cba42e0bb022e93f2c1abef2" ]
[ "ASC2:b7e722755206e4d6fccd36d0", "ASC2:2c65847308e76e26a89e029a" ]
[ "HYP:DCH:a1e5178f547ba84472f1dad6" ]
{"qa_id":"QA:779acf43129a426a8d143c0f","qa_group_id":"QAG:0cde08afe4355748cde33a28","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Sole CTLA-4 and PD-L1 inhibition only moderately decreased metasta...
QA:77f2f62fe12fb9736587c6c1
QAG:0dd162e87af8b403c07d4f83
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Recently, DNA damage was associated with induction of CXCL10 as well as other proinflammatory genes, 27 while in pancreatic cancer ferroptosis-induced 8-OHdG formation led to STING activation"? Return the original wording with paper, Claim, and Evidence Span references...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d9106fb1a39aeaba89caf796","quotes":["Recently, DNA damage has been associated with induction of CXCL10 as well as...
[ "CLM:d9106fb1a39aeaba89caf796", "CLM:0012c5301a22fe572fa575f9" ]
[ "PMCID:PMC10423492" ]
[ "SPAN:84dbcd15587fa3e97552ed60" ]
[]
[]
{"qa_id":"QA:77f2f62fe12fb9736587c6c1","qa_group_id":"QAG:0dd162e87af8b403c07d4f83","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Recently, DNA damage was associated with induction of CXCL10 as we...
QA:7829773177bbab3331d49b3d
QAG:cb9258d3a0ecdc8ec918b936
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In this study, we also elaborated the molecular mechanisms by which CHSY1 promotes PD-L1 expression in CRC cells and led to CD8 + T cell efflux"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return th...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:303238149456ec966f944755","quotes":["In this study, we also elaborated the molecular mechanisms by which CHSY1 pr...
[ "CLM:303238149456ec966f944755", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC10519095" ]
[ "SPAN:2bdc3cd9c54c34701f36a4c1" ]
[]
[]
{"qa_id":"QA:7829773177bbab3331d49b3d","qa_group_id":"QAG:cb9258d3a0ecdc8ec918b936","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In this study, we also elaborated the molecular mechanisms by whic...
QA:7c332fec7de8a36487b2ad9b
QAG:b4cb2050d02f31dd76265b1c
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Given that the presence of METs in the two cohorts was significantly related to the distant metastasis and poor prognosis of CC patients, we tried to investigate whether METs promoted the metastatic ability of colon cancer in vitro"? Return the original wording with pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f3a65a928cc72a9ccca00946","quotes":["Given that the presence of METs in the two cohorts was significantly related...
[ "CLM:f3a65a928cc72a9ccca00946", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC8671452" ]
[ "SPAN:a17c761058c77d6b59396b97" ]
[]
[]
{"qa_id":"QA:7c332fec7de8a36487b2ad9b","qa_group_id":"QAG:b4cb2050d02f31dd76265b1c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Given that the presence of METs in the two cohorts was significant...
QA:7e27db20b2a343e83577e947
QAG:75204dc4bd3ccbe8ceb69287
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "the MWA group, which received MWA and an isotype control antibody; the TIGIT group, which was treated with anti-TIGIT; and the MWA plus TIGIT group, which was treated with MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aba70333281dfd5fb41be940","quotes":["Mice with MC38 colon cancer were divided into four groups as follows: the co...
[ "CLM:aba70333281dfd5fb41be940", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:136a8bd68a3701f90147967f" ]
[]
[]
{"qa_id":"QA:7e27db20b2a343e83577e947","qa_group_id":"QAG:75204dc4bd3ccbe8ceb69287","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"the MWA group, which received MWA and an isotype control antibody;...
QA:7edd86c788212f885ef29ef5
QAG:9425bd5fda4e6b9cc039125e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In vitro and in vivo assays demonstrated that the numbers of migratory and invasive SW480 and RKO cells in groups administered CM from THP-1 cells promoted with PMA, which were treated with exosomes derived from miR-934-overexpressing or miR-934-downregulated CRC cells...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:180fec3d65f960d9159234a9","quotes":["In vitro and in vivo assays demonstrated that the numbers of migratory and i...
[ "CLM:180fec3d65f960d9159234a9", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:b8226aa0425918e91db8b76a" ]
[]
[]
{"qa_id":"QA:7edd86c788212f885ef29ef5","qa_group_id":"QAG:9425bd5fda4e6b9cc039125e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In vitro and in vivo assays demonstrated that the numbers of migra...
QA:7f654ba809380e025bdb3f10
QAG:8c312c2aa7280681bbceff68
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "17 Our present results showed that knockout of AMPKα2 increased the tumour growth and liver injury in the colon cancer cell liver metastasis mouse model (Figure 2 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance re...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f1bafed84fd7895c46aca148","quotes":["17 Our present results showed that knockout of AMPKα2 enhanced the tumour gr...
[ "CLM:f1bafed84fd7895c46aca148", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC6378193" ]
[ "SPAN:3215545eef2a8fb56297319d" ]
[]
[]
{"qa_id":"QA:7f654ba809380e025bdb3f10","qa_group_id":"QAG:8c312c2aa7280681bbceff68","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"17 Our present results showed that knockout of AMPKα2 increased th...
QA:8083d07e9557b0923210cc79
QAG:561e4727a095fc4a47bc9f50
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The results showed that increased expression of IL-33 in CRC cells increased their tumor take, growth, and liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a7cb5ba5af07fbb719196761","quotes":["The results showed that increased expression of IL-33 in CRC cells enhanced ...
[ "CLM:a7cb5ba5af07fbb719196761", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC5630136" ]
[ "SPAN:d5a4bb47f36cabd492e85803" ]
[]
[]
{"qa_id":"QA:8083d07e9557b0923210cc79","qa_group_id":"QAG:561e4727a095fc4a47bc9f50","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results showed that increased expression of IL-33 in CRC cells...
QA:809a15bb7f30529fab6efe9f
QAG:9f8b7b811703bd0ab4e1d7c0
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "and the MWA plus TIGIT group, which received MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; asse...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b5527355866d46107bfb7ef8","quotes":["Mice with MC38 colon cancer were divided into four groups as follows: the co...
[ "CLM:b5527355866d46107bfb7ef8", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8935077" ]
[ "SPAN:136a8bd68a3701f90147967f" ]
[]
[]
{"qa_id":"QA:809a15bb7f30529fab6efe9f","qa_group_id":"QAG:9f8b7b811703bd0ab4e1d7c0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"and the MWA plus TIGIT group, which received MWA and anti-TIGIT\"?...
QA:80bef0f146903d2f58d4fe4c
QAG:569ae24e096ee17df935ba7a
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Figure 1 Alcohol facilitates liver metastasis (A) Alcohol pretreatment promoted colon cancer cell metastasis to the liver in BALB/c (Ctrl, n = 8; Alco, n = 7) and C57BL/6 (n = 5) mice, but did not influence tumor growth in the spleen or the correlation between tumor bu...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7daf8075eb6404f5979b04e5","quotes":["Figure 1 Alcohol facilitates liver metastasis (A) Alcohol pretreatment promo...
[ "CLM:7daf8075eb6404f5979b04e5", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC10492032" ]
[ "SPAN:26ee743ad8376ccb599f57da" ]
[]
[]
{"qa_id":"QA:80bef0f146903d2f58d4fe4c","qa_group_id":"QAG:569ae24e096ee17df935ba7a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Figure 1 Alcohol facilitates liver metastasis (A) Alcohol pretreat...
QA:816ead2ba53c736a1764896f
QAG:eb544ccd0cf55b0e756d330e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "a, b Changes in the mRNA and protein expression levels of hnRNPU and hnRNPR promoted by transfection of their knockdown plasmids. c, d Levels of total and exosomal miR-934 after transfection of shhnRNPU, shhnRNPR, or their negative control plasmids into HCT8 and LoVo c...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1809e57319b4b2be1b2165d9","quotes":["Effect of the RNA binding proteins hnRNPU and hnRNPR on the expression of CR...
[ "CLM:1809e57319b4b2be1b2165d9", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC7678301" ]
[ "SPAN:980eab8b3eace39abb9708e3" ]
[]
[]
{"qa_id":"QA:816ead2ba53c736a1764896f","qa_group_id":"QAG:eb544ccd0cf55b0e756d330e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"a, b Changes in the mRNA and protein expression levels of hnRNPU a...
QA:82bdd6c9525fb9881bc8b1d0
QAG:2e5ffb5f716b3606a63e4744
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "According to the results, when CRC cells with downregulated expression of MGP were co-cultured with antigen-specific CD8 + T cells, the expression of common markers of CD8 + T cell exhaustion (for example, LAG3, PD1, TIGIT, and TIM3) was noticeably decreased (Figure 4 ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1e0af15ba384d37908630764","quotes":["According to the results, when CRC cells with downregulated expression of MG...
[ "CLM:1e0af15ba384d37908630764", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8990480" ]
[ "SPAN:be98e35166e3a9ece120634a" ]
[]
[]
{"qa_id":"QA:82bdd6c9525fb9881bc8b1d0","qa_group_id":"QAG:2e5ffb5f716b3606a63e4744","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"According to the results, when CRC cells with downregulated expres...
QA:82eab55b42509773bd08dc87
QAG:a1857ea7dd445ea466035766
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "have confirmed that decreased Th17 infiltration is associated with CRC progression in patients , which is in agreement with our findings"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5a5d704321beef17dc69d164","quotes":["Ling et al. have confirmed that decreased Th17 infiltration is associated wi...
[ "CLM:5a5d704321beef17dc69d164", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC8908934" ]
[ "SPAN:480cd153a97b6ac96e16a4d7" ]
[]
[]
{"qa_id":"QA:82eab55b42509773bd08dc87","qa_group_id":"QAG:a1857ea7dd445ea466035766","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"have confirmed that decreased Th17 infiltration is associated with...
QA:84952a849e3fa82703cec4ed
QAG:de63a9a5ac8398d3015cff1e
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "1 TCF4 expression is elevated in colorectal cancer hepatic metastasis compared with the primary site and was correlated with tumor-associated macrophage recruitment in the tumor area"? Return the original wording with paper, Claim, and Evidence Span references. Integr...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7aeb6054393f56069dcd1666","quotes":["Fig. 1 TCF4 expression is elevated in colorectal cancer hepatic metastasis c...
[ "CLM:7aeb6054393f56069dcd1666", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC8476489" ]
[ "SPAN:d38e2754eade644eba19bae4" ]
[]
[]
{"qa_id":"QA:84952a849e3fa82703cec4ed","qa_group_id":"QAG:de63a9a5ac8398d3015cff1e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"1 TCF4 expression is elevated in colorectal cancer hepatic metasta...
QA:84ba9017d06018b7d5ea2fd2
QAG:91bec5b334d02be2dc5681d7
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Our previous study indicated that Matrix Gla protein(MGP) could facilitate CD8 + T cell depletion through activation of the NF-κB pathway, which led to liver metastasis of CRC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated pr...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a573fc2b308d5e1b51a3663e","quotes":["Our previous study indicated that Matrix Gla protein(MGP) could facilitate C...
[ "CLM:a573fc2b308d5e1b51a3663e", "CLM:7795cac80522afb92a0dc44d" ]
[ "PMCID:PMC10519095" ]
[ "SPAN:ce3c5b8bc5e4b57a18d3f09c" ]
[]
[]
{"qa_id":"QA:84ba9017d06018b7d5ea2fd2","qa_group_id":"QAG:91bec5b334d02be2dc5681d7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our previous study indicated that Matrix Gla protein(MGP) could fa...
QA:87f762c221c36f633d11e272
QAG:4b6ac7b2a9505e3ca728f75b
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "In colorectal cancer patients, high serum IL-6 levels was associated with a large liver metastasis volume"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper,...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:649877980b9085f6fa635889","quotes":["In colorectal cancer patients, high serum IL-6 levels are associated with a ...
[ "CLM:649877980b9085f6fa635889", "CLM:71ac756b9724a4423f9240ec" ]
[ "PMCID:PMC10492032" ]
[ "SPAN:a4a694dbf5fb8c0db239873d" ]
[]
[]
{"qa_id":"QA:87f762c221c36f633d11e272","qa_group_id":"QAG:4b6ac7b2a9505e3ca728f75b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In colorectal cancer patients, high serum IL-6 levels was associat...
QA:89104ec84ad89fafc599bb6c
QAG:dc202b1a1425ff86e56128d8
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "The expression of the M2 markers , (CD206, arginase-1, IL10, and CD163) was increased in macrophages incubated with exosomes derived from CRC cells exhibiting high miR-934 expression compared to that in macrophages incubated with exosomes from cells exhibiting low miR-...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:15e244a548ca920383903c3d","quotes":["The expression of the M2 m...
[ "CLM:15e244a548ca920383903c3d", "CLM:0478df56bd5aa1173e674769", "CLM:30e80831b40caad54c0fcbf8", "CLM:5ee0e6fdcf248640c3592640", "CLM:11b6f95fd25edf270388a4d7" ]
[ "PMCID:PMC7678301", "PMCID:PMC10405073", "PMCID:PMC10207961" ]
[ "SPAN:b6b151f26760ee21dcaa7568", "SPAN:3c7fd241674a4cc17255eef4", "SPAN:7a8551dd0da8889569df74de", "SPAN:183cf6a7571e588e15e1d618", "SPAN:cbb10ee4d2e2340aafcafd9c" ]
[ "ASC2:ecf6ff7a693169df251747c7", "ASC2:2cecb77a3806a8b46afd4433" ]
[ "HYP:DCH:dfe89acf1e41b1ab9bea76c7", "HYP:DCH:675848c936e9c74948f9fba3" ]
{"qa_id":"QA:89104ec84ad89fafc599bb6c","qa_group_id":"QAG:dc202b1a1425ff86e56128d8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The expression of the M2 markers , (CD206, arginase-1, IL10, and C...
QA:8adaf0843b5b8d25821ce1f6
QAG:e65aff7eb81281738e05cac5
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Our study showed that HSCs may contribute significantly to an immunosuppressive hepatic microenvironment, resulting in increased CRC cell proliferation and migration"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2599ca5b2c3257e2a49ce648","quotes":["Our study showed that HSCs may contribute significantly to an immunosuppress...
[ "CLM:2599ca5b2c3257e2a49ce648", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC6754330" ]
[ "SPAN:9139aebaf7fef9a1477e9f9d" ]
[]
[]
{"qa_id":"QA:8adaf0843b5b8d25821ce1f6","qa_group_id":"QAG:e65aff7eb81281738e05cac5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our study showed that HSCs may contribute significantly to an immu...
QA:8b8e04c95b26ff93123047c6
QAG:bf13ef8f144933ca47e319a6
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "Itaconic acid is produced by IRG1 through cis -aconitic acid and its gene expression is promoted by LPS treatment in macrophages"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact support...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:30e80831b40caad54c0fcbf8","quotes":["Itaconic acid is produced by IRG1 through cis -acon...
[ "CLM:30e80831b40caad54c0fcbf8", "CLM:0478df56bd5aa1173e674769", "CLM:ff6e922222af5bdefb9ec37b" ]
[ "PMCID:PMC10405073", "PMCID:PMC6378193" ]
[ "SPAN:3c7fd241674a4cc17255eef4", "SPAN:7a8551dd0da8889569df74de", "SPAN:480e125802ff00efe2abebdf" ]
[ "ASC2:08e8e65564c80145294cdffc" ]
[]
{"qa_id":"QA:8b8e04c95b26ff93123047c6","qa_group_id":"QAG:bf13ef8f144933ca47e319a6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Itaconic acid is produced by IRG1 through cis -aconitic acid and i...
QA:8c0a069581671e4de8f79e1c
QAG:47dbc11ad0738e18f9be0110
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "A 34-year-old woman with metastatic MSI-H descending colon cancer, who had peritonitis due to perforation of primary tumor and received transverse colostomy were enrolled (Patient 1)"? Return the original wording with paper, Claim, and Evidence Span references. Integr...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1d7402f04bc3444ae5bb921e","quotes":["A 34-year-old woman with metastatic MSI-H descending colon cancer, who had p...
[ "CLM:1d7402f04bc3444ae5bb921e", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC9705377" ]
[ "SPAN:c174613ecfae5b541be612e3" ]
[]
[]
{"qa_id":"QA:8c0a069581671e4de8f79e1c","qa_group_id":"QAG:47dbc11ad0738e18f9be0110","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"A 34-year-old woman with metastatic MSI-H descending colon cancer,...
QA:90130111c552386abbb445cd
QAG:42d8a5afe5dd7ade4de00b45
provenance_qa
exact_evidence_retrieval
provenance_qa
G013
en
train
Which exact source passage supports the statement "A stepwise increased serum MIC-1 levels in patients with benign conditions (median, 603.6 pg/mL; range, 154.8-3975.8 pg/mL; P=0.0001) and CRC (median, 859.2pg/mL; range, 112.0-5178.1 pg/mL; P<0.0001) in comparison with healthy control subjects (median, 359.9 pg/mL; ran...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:cff1b311d724cc4c7c45a1ad","quotes":["A stepwise increased serum MIC-1 levels in patients with benign conditions (...
[ "CLM:cff1b311d724cc4c7c45a1ad", "CLM:0478df56bd5aa1173e674769" ]
[ "PMCID:PMC5421897" ]
[ "SPAN:82b11f65635cee0a470e4c64" ]
[]
[]
{"qa_id":"QA:90130111c552386abbb445cd","qa_group_id":"QAG:42d8a5afe5dd7ade4de00b45","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"A stepwise increased serum MIC-1 levels in patients with benign co...