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value | question stringlengths 148 1.41k | answer stringlengths 718 10.8k | claim_ids listlengths 0 8 | paper_ids listlengths 1 5 | evidence_span_ids listlengths 0 7 | association_ids listlengths 0 4 | hypothesis_ids listlengths 0 4 | record_json stringlengths 4.37k 33.7k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QA:9222a00f388bada179e1f7f9 | QAG:43a2df037e696b1054490a9e | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "This study showed that pancreatic cancer patients with an alcohol exposure history displayed increased susceptibility to liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exac... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c88720186ee385661709b3c2","quotes":["This study showed that pancreatic cancer patients with an alcohol exposure h... | [
"CLM:c88720186ee385661709b3c2",
"CLM:04bbc50258758972aa54295d"
] | [
"PMCID:PMC10492032"
] | [
"SPAN:cf706ec74eee5efe4164afdd"
] | [] | [] | {"qa_id":"QA:9222a00f388bada179e1f7f9","qa_group_id":"QAG:43a2df037e696b1054490a9e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"This study showed that pancreatic cancer patients with an alcohol ... |
QA:96fdae2f376a8ca4fcbddb87 | QAG:a62555ed300acf9df217f07f | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Another study by Syed Khaja et al ( 17 ) revealed that numbers of CD4 + FOXP3 + Tregs were increased in colorectal cancer tissues"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact suppor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:98a9abc1011c1d5436bb9a89","quotes":["Another study by Syed Khaja et al ( 17 ) revealed that numbers of CD4 + FOXP... | [
"CLM:98a9abc1011c1d5436bb9a89",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7400973"
] | [
"SPAN:289d656f32f0114ccbb440bd"
] | [] | [] | {"qa_id":"QA:96fdae2f376a8ca4fcbddb87","qa_group_id":"QAG:a62555ed300acf9df217f07f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Another study by Syed Khaja et al ( 17 ) revealed that numbers of ... |
QA:973beaa90a8137bfce04fd2f | QAG:130cc1f53022c0d0de0f3b1e | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In contrast, our study extends the concept by demonstrating that chemotherapy promoted re-programming of the metastatic microenvironment can occur even in the absence of a primary CRC tumor"? Return the original wording with paper, Claim, and Evidence Span references.
... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:590d8db0963a5c4dc350f0fd","quotes":["In contrast, our study extends the concept by demonstrating that chemotherap... | [
"CLM:590d8db0963a5c4dc350f0fd",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10494354"
] | [
"SPAN:4dfc4cba83aebc1893fe46fe"
] | [] | [] | {"qa_id":"QA:973beaa90a8137bfce04fd2f","qa_group_id":"QAG:130cc1f53022c0d0de0f3b1e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In contrast, our study extends the concept by demonstrating that c... |
QA:97e1dd2a3933f136bd1cbd43 | QAG:8aaa927ca57a34a6a3af54ca | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "At the metastatic site, mCRC liver tumors were heavily infiltrated by TAM, which exhibited a robust ability to dampen endogenous anti-tumor lymphocyte activity"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance require... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3c9947cdb5135d5ca5bd3ac4","quotes":["At the metastatic site, mCRC liver tumors were heavily infiltrated by TAM, w... | [
"CLM:3c9947cdb5135d5ca5bd3ac4",
"CLM:067d965206482629e87c81c8"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:751a9d22e3836b2b8baa2ff7"
] | [] | [] | {"qa_id":"QA:97e1dd2a3933f136bd1cbd43","qa_group_id":"QAG:8aaa927ca57a34a6a3af54ca","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"At the metastatic site, mCRC liver tumors were heavily infiltrated... |
QA:983b52edd7bf101c4d0d4c1f | QAG:3857fc89afce9d9deb688aef | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Moreover, the combination of MGP knockdown and αPD1 might have led to synergistic resistance against CRC liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting pas... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:154d43bd9230bdb9a5f7b1ee","quotes":["Moreover, the combination of MGP knockdown and αPD1 might have contributed t... | [
"CLM:154d43bd9230bdb9a5f7b1ee",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:026ec88db53b9447a518fd21"
] | [] | [] | {"qa_id":"QA:983b52edd7bf101c4d0d4c1f","qa_group_id":"QAG:3857fc89afce9d9deb688aef","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Moreover, the combination of MGP knockdown and αPD1 might have led... |
QA:99af41d64f381eb30179f258 | QAG:20fe194837dcd36343123050 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The molecular mechanisms involved in miR-18a promoted M1 macrophages were further studied and we found that miR-18a-mediated induction of macrophage IFNγ is required for inhibition of liver metastasis of colon cancer and that macrophage IRF2 is targeted by miR-18a"? Re... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2489bf6ed31a46ab115f1b01","quotes":["We found that liver macrophages are polarized to M1 macrophages after miR-18... | [
"CLM:2489bf6ed31a46ab115f1b01",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC5041936"
] | [
"SPAN:239af5f12d3b0d89eb749a61"
] | [] | [] | {"qa_id":"QA:99af41d64f381eb30179f258","qa_group_id":"QAG:20fe194837dcd36343123050","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The molecular mechanisms involved in miR-18a promoted M1 macrophag... |
QA:9abaf265f3c05b4a21320409 | QAG:9f1eb13b01ac7e30b49cc4bc | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "qRT-PCR and western blotting were performed to compare the variations in PD-L1 mRNA and protein expression after MGP knockdown and overexpression, which revealed that with decrease in MGP expression, PD-L1 mRNA and protein expression also decreased (Figure 5 F and 5 G)... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9fe4e66557fdd3223d510f82","quotes":["As revealed by immunohistochemistry, high expression of MGP in patients with... | [
"CLM:9fe4e66557fdd3223d510f82",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:19c9bb30ba9e8758ebda36d2"
] | [] | [] | {"qa_id":"QA:9abaf265f3c05b4a21320409","qa_group_id":"QAG:9f1eb13b01ac7e30b49cc4bc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"qRT-PCR and western blotting were performed to compare the variati... |
QA:9c70d3616514c5bfff63cf56 | QAG:326edd622e86878bdcee5673 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The impact of S1PR1 on CRC cell metastasis was then investigated following xenotransplantation into nude mice through intrasplenic injection, and we found that the number of distant masses was increased in S1PR1 overexpression tumor cells at 6 weeks post injection (Fig... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fa6308c082704423d86e3421","quotes":["The impact of S1PR1 on CRC cell metastasis was then investigated following x... | [
"CLM:fa6308c082704423d86e3421",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:8e1f05eb44b66563acb93c1e"
] | [] | [] | {"qa_id":"QA:9c70d3616514c5bfff63cf56","qa_group_id":"QAG:326edd622e86878bdcee5673","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The impact of S1PR1 on CRC cell metastasis was then investigated f... |
QA:a043e0d9e11eb69faafdc77d | QAG:6cfae3161451608e0cafecc5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In this study, we found that the expression level of STING was lower than colorectal cancer liver metastases than in the primary lesions, and it was also significantly lower in M2-type macrophages associated with liver metastases"? Return the original wording with pape... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a99443ca367066bce3effb08","quotes":["In this study, we found that the expression level of STING was lower in colo... | [
"CLM:a99443ca367066bce3effb08",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:7fac22623dc3d5b7074dd432"
] | [] | [] | {"qa_id":"QA:a043e0d9e11eb69faafdc77d","qa_group_id":"QAG:6cfae3161451608e0cafecc5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In this study, we found that the expression level of STING was low... |
QA:a12974b82b4e7d0dcfaa2131 | QAG:741e194dafc9b87893e54b4a | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "As revealed by immunohistochemistry, high expression of MGP in patients with CRC was associated with an upregulated PD-L1 expression, and vice versa (Figure 5 E). qRT-PCR and western blotting were performed to compare the variations in PD-L1 mRNA and protein expression... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e10c9dc3497b9b9b5f1f4cea","quotes":["As revealed by immunohistochemistry, high expression of MGP in patients with... | [
"CLM:e10c9dc3497b9b9b5f1f4cea",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:19c9bb30ba9e8758ebda36d2"
] | [] | [] | {"qa_id":"QA:a12974b82b4e7d0dcfaa2131","qa_group_id":"QAG:741e194dafc9b87893e54b4a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"As revealed by immunohistochemistry, high expression of MGP in pat... |
QA:a1611b5d2e7283c52689bd56 | QAG:1ea271f6edf4bbf9c6b5818f | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Recently, fibroblasts have been shown to inhibit cancer progression in a mouse model of pancreatic ductal adenocarcinoma, and depletion of these cells led to a diminished survival of the tumor-bearing mice"? Return the original wording with paper, Claim, and Evidence S... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:71ac756b9724a4423f9240ec","quotes":["Recently, fibroblasts have been shown to inhibit cancer progression in a mou... | [
"CLM:71ac756b9724a4423f9240ec",
"CLM:0012c5301a22fe572fa575f9"
] | [
"PMCID:PMC6700499"
] | [
"SPAN:0736b327afc27cb5dc277266"
] | [] | [] | {"qa_id":"QA:a1611b5d2e7283c52689bd56","qa_group_id":"QAG:1ea271f6edf4bbf9c6b5818f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Recently, fibroblasts have been shown to inhibit cancer progressio... |
QA:a36bd80544c4d919e838f00a | QAG:0e7f8fbee50775c23c267e0a | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "the body might accumulate antitumor immune cells in the TME and secrete IL-9 to produce antitumor immunity and inhibit local invasion as well as distant metastasis of tumor cells, which finally results in improved prognosis"? Return the original wording with paper, Cla... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5e3819a2807e080765297b28","quotes":["Furthermore, we found that survival time in colon carcinoma cases with posit... | [
"CLM:5e3819a2807e080765297b28",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6598323"
] | [
"SPAN:707966fc77ae377d0f25dd3a"
] | [] | [] | {"qa_id":"QA:a36bd80544c4d919e838f00a","qa_group_id":"QAG:0e7f8fbee50775c23c267e0a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"the body might accumulate antitumor immune cells in the TME and se... |
QA:a575ca145bc87e23df605563 | QAG:2ffd4ce13186fb744921221c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The number of PMN-MDSCs is increased in the tumors of HNC, colon cancer, and NSCLC patients, and the combination of serum LOX1 with neutrophil markers allows the detection of PMN-MDSC in tissues"? Return the original wording with paper, Claim, and Evidence Span referen... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fb3de6d44f915d701b99f8de","quotes":["The number of PMN-MDSCs is significantly increased in the tumors of HNC, col... | [
"CLM:fb3de6d44f915d701b99f8de",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC9926712"
] | [
"SPAN:f3f749fc17366c36055af824"
] | [] | [] | {"qa_id":"QA:a575ca145bc87e23df605563","qa_group_id":"QAG:2ffd4ce13186fb744921221c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The number of PMN-MDSCs is increased in the tumors of HNC, colon c... |
QA:a6363595b36256d5509217b9 | QAG:96925da60b612d69e7a3015d | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Importantly, Pearson’s correlation analysis indicated that TCF4 expression was correlated with TAMs numbers in the colorectal cancer samples and M2 macrophage markers expression (Fig. 1 I, J)"? Return the original wording with paper, Claim, and Evidence Span references... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9be3b93a4c68d406a9b4a8fe","quotes":["Importantly, Pearson’s correlation analysis indicated that TCF4 expression w... | [
"CLM:9be3b93a4c68d406a9b4a8fe",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:df55170122004a3b32a9babc"
] | [] | [] | {"qa_id":"QA:a6363595b36256d5509217b9","qa_group_id":"QAG:96925da60b612d69e7a3015d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Importantly, Pearson’s correlation analysis indicated that TCF4 ex... |
QA:a6a55860219123e7e38c46a4 | QAG:d4e951a8376a4e10ae5ad6ef | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Furthermore, we found that the combination of MWA and anti-TIGIT treatment prolonged the survival of mice with MC38 colon cancer and inhibited tumor growth"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirement... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2f9d9b67ef2d1d8e9dfcfae8","quotes":["Furthermore, we found that the combination of MWA and anti-TIGIT treatment p... | [
"CLM:2f9d9b67ef2d1d8e9dfcfae8",
"CLM:32074368e9eaad5d6640b1f3"
] | [
"PMCID:PMC8935077"
] | [
"SPAN:6f6b3a28460ab0cfca725827"
] | [] | [] | {"qa_id":"QA:a6a55860219123e7e38c46a4","qa_group_id":"QAG:d4e951a8376a4e10ae5ad6ef","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Furthermore, we found that the combination of MWA and anti-TIGIT t... |
QA:a6ead88572ad63d787e27acd | QAG:7217db8955cb27f47862f5de | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Ten patients with CRC liver metastasis undergoing liver partial resection in the First Affiliated Hospital of Nanjing Medical University were enrolled in the present study"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated proven... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:65297b0426eed51fcf488d4d","quotes":["Ten patients with CRC liver metastasis undergoing liver partial resection in... | [
"CLM:65297b0426eed51fcf488d4d",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10030919"
] | [
"SPAN:7d508414f6790540affeda8b"
] | [] | [] | {"qa_id":"QA:a6ead88572ad63d787e27acd","qa_group_id":"QAG:7217db8955cb27f47862f5de","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Ten patients with CRC liver metastasis undergoing liver partial re... |
QA:a720372c987260fe6e2bdf11 | QAG:7e6cbd52105858ab2421ceb1 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "b qPCR analysis of the changes in M2 marker (CD163, CD206, Arginase-1, and IL-10) expression levels after HBMDMs received CRC cell-derived exosomes (* p < 0.05; ** p < 0.01; *** p < 0.001)"? Return the original wording with paper, Claim, and Evidence Span references.
... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0a738d052dc087fde9e46f08","quotes":["The macrophage marker CD11b was measured with flow ... | [
"CLM:0a738d052dc087fde9e46f08",
"CLM:0478df56bd5aa1173e674769",
"CLM:0012c5301a22fe572fa575f9",
"CLM:8f46d77ceb0e60c55518d13d"
] | [
"PMCID:PMC7678301",
"PMCID:PMC10519095",
"PMCID:PMC10964083"
] | [
"SPAN:3f5496e55b250536878ab070",
"SPAN:8795903c20b78c766b434545",
"SPAN:cba42e0bb022e93f2c1abef2"
] | [
"ASC2:55153f6930317c80e60e9ed8",
"ASC2:94978fef6938243617b8ef57"
] | [
"HYP:DCH:10cc84f7a53fb1747a7ea54a"
] | {"qa_id":"QA:a720372c987260fe6e2bdf11","qa_group_id":"QAG:7e6cbd52105858ab2421ceb1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"b qPCR analysis of the changes in M2 marker (CD163, CD206, Arginas... |
QA:a76db5fba67cd9ef5c2e42b9 | QAG:654b37f794f37c5072af0caa | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Our study suggests that targeting the CCL2/CCR2 chemokine axis decreased TAM at the metastatic site, disrupting the immunosuppressive TME and rendering mCRC susceptible to anti-tumor T-cell responses"? Return the original wording with paper, Claim, and Evidence Span re... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:79a7660d440bbb4e689629f8","quotes":["Our study suggests that targeting the CCL2/CCR2 chemokine axis decreases TAM... | [
"CLM:79a7660d440bbb4e689629f8",
"CLM:04bbc50258758972aa54295d"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:ec9ade3dbb77a92bf42ee19c"
] | [] | [] | {"qa_id":"QA:a76db5fba67cd9ef5c2e42b9","qa_group_id":"QAG:654b37f794f37c5072af0caa","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our study suggests that targeting the CCL2/CCR2 chemokine axis dec... |
QA:a80b243393ae6b470f9a2f55 | QAG:f5680ad4da1110afd76b5c75 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In contrast, the same combination did not improve tumour growth of subcutaneously grown CRC organoids, while it decreases their metastatic growth in liver"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f892b11dba094bdc378d2b39","quotes":["In contrast, the same combination does not affect tumour growth of subcutane... | [
"CLM:f892b11dba094bdc378d2b39",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10423492"
] | [
"SPAN:4cbe24372a9a7cbdaf75c957"
] | [] | [] | {"qa_id":"QA:a80b243393ae6b470f9a2f55","qa_group_id":"QAG:f5680ad4da1110afd76b5c75","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In contrast, the same combination did not improve tumour growth of... |
QA:a95622f6e2a7b310ea7143b2 | QAG:008dc1a838fe716e0cf2afab | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "(A) The Tie2-PI3K/Akt/mTOR in macrophages of liver tissues showed no significant differences in non-tumor environment, and macrophages’ specific deletion of SHP2 increased levels of phosphorylated Tie2-PI3K/Akt/mTOR as well as the expression of COX-2, VEGF, MMP-2/-9 in... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5ee0e6fdcf248640c3592640","quotes":["(A) The Tie2-PI3K/Akt/mTOR in macrophages of liver ... | [
"CLM:5ee0e6fdcf248640c3592640",
"CLM:7795cac80522afb92a0dc44d",
"CLM:11b6f95fd25edf270388a4d7"
] | [
"PMCID:PMC10207961",
"PMCID:PMC7678301"
] | [
"SPAN:cbb10ee4d2e2340aafcafd9c",
"SPAN:183cf6a7571e588e15e1d618"
] | [
"ASC2:2cecb77a3806a8b46afd4433"
] | [
"HYP:DCH:eb9fb837c36f0524a82a88df"
] | {"qa_id":"QA:a95622f6e2a7b310ea7143b2","qa_group_id":"QAG:008dc1a838fe716e0cf2afab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"(A) The Tie2-PI3K/Akt/mTOR in macrophages of liver tissues showed ... |
QA:ad571de553208b09e98c96cc | QAG:00f75ad90c0cca9d94233ebe | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "We found that the anti-CXCL13 antibody or knockdown of CXCR5 in CRC cells could inhibit the activation of the NFκB signaling pathway promoted by the CM of miR-934-overexpressing PMA-treated THP-1 cells (Fig. 8 b)"? Return the original wording with paper, Claim, and Evi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aca00b25b22380677827e5c8","quotes":["We found that the anti-CXCL13 antibody or knockdown of CXCR5 in CRC cells co... | [
"CLM:aca00b25b22380677827e5c8",
"CLM:32074368e9eaad5d6640b1f3"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:2f87a0a1126abc9d9fb0a554"
] | [] | [] | {"qa_id":"QA:ad571de553208b09e98c96cc","qa_group_id":"QAG:00f75ad90c0cca9d94233ebe","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"We found that the anti-CXCL13 antibody or knockdown of CXCR5 in CR... |
QA:ae3d4031785edfd4ba52e173 | QAG:9d9d0e2ca5e0fca4c25cb4b3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "(A) Macrophages’ specific deletion of SHP2 promoted amounts of colorectal cancer nodules in liver and the statistical data, scar bar: 2 mm; (B) Macrophages’ specific deletion of SHP2 increased the fluorescent intensity of Tie2 in CD68/macrophages marker cells and the s... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1919a6ca1fd65c9cd4e9bf97","quotes":["(A) Macrophages’ specific deletion of SHP2 accelerated amounts of colorectal... | [
"CLM:1919a6ca1fd65c9cd4e9bf97",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC10207961"
] | [
"SPAN:752a5402c5fadc5da0b989a2"
] | [] | [] | {"qa_id":"QA:ae3d4031785edfd4ba52e173","qa_group_id":"QAG:9d9d0e2ca5e0fca4c25cb4b3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"(A) Macrophages’ specific deletion of SHP2 promoted amounts of col... |
QA:ae7878d648b1fbbbca53a9f3 | QAG:6eddebcb03e622dda6f21e6d | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The combination of MGP knockdown and αPD1 (anti-PD1) led to synergistic resistance against liver metastasis, which may provide new insights into CRC immunotherapy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f10b00e03249f6ce269e1eb0","quotes":["The combination of MGP knockdown and αPD1 (anti-PD1... | [
"CLM:f10b00e03249f6ce269e1eb0",
"CLM:71ac756b9724a4423f9240ec",
"CLM:2f18a10139e57fbed1497590"
] | [
"PMCID:PMC8990480",
"PMCID:PMC10519095"
] | [
"SPAN:84bf9aff324fa321ccc4186e",
"SPAN:7f4de2ae1e00288fea01f48f"
] | [
"ASC2:b7e722755206e4d6fccd36d0"
] | [
"HYP:DCH:885c592cf5d79c6c01f9e21d"
] | {"qa_id":"QA:ae7878d648b1fbbbca53a9f3","qa_group_id":"QAG:6eddebcb03e622dda6f21e6d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The combination of MGP knockdown and αPD1 (anti-PD1) led to synerg... |
QA:b01f541055feef344e03672d | QAG:541edab3cda7df981a5821c8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The results showed that mice bearing liver metastasis of colon cancer cells had much higher levels of ALT and AST (subcutaneous tumour vs liver metastasis) in blood than mice with subcutaneous tumour xenograft (Figure 1 C), suggesting that liver metastasis led to much ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ff6e922222af5bdefb9ec37b","quotes":["The results showed that mice bearing liver metastasis of colon cancer cells ... | [
"CLM:ff6e922222af5bdefb9ec37b",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6378193"
] | [
"SPAN:480e125802ff00efe2abebdf"
] | [] | [] | {"qa_id":"QA:b01f541055feef344e03672d","qa_group_id":"QAG:541edab3cda7df981a5821c8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results showed that mice bearing liver metastasis of colon can... |
QA:b04792c70216015804c95c62 | QAG:fc3e3ecfe0a3eba218481141 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In vitro and in vivo assays demonstrated that the numbers of migratory and invasive SW480 and RKO cells in groups administered CM from THP-1 cells stimulated with PMA, which were treated with exosomes derived from miR-934-overexpressing or miR-934-downregulated CRC cel... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9e76905a5f385893d96e4368","quotes":["In vitro and in vivo assays demonstrated that the numbers of migratory and i... | [
"CLM:9e76905a5f385893d96e4368",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:b8226aa0425918e91db8b76a"
] | [] | [] | {"qa_id":"QA:b04792c70216015804c95c62","qa_group_id":"QAG:fc3e3ecfe0a3eba218481141","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In vitro and in vivo assays demonstrated that the numbers of migra... |
QA:b1cbef4c51a5e692d18fbe8d | QAG:64434a1291a93029602f29fb | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Using a murine model of mCRC that retained these findings from human disease, we show that targeting CCR2 reduces TAM accumulation in liver metastasis and restores anti-tumor immunity"? Return the original wording with paper, Claim, and Evidence Span references.
Integ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:32074368e9eaad5d6640b1f3","quotes":["Using a murine model of mCRC that recapitulates these findings from human di... | [
"CLM:32074368e9eaad5d6640b1f3",
"CLM:04bbc50258758972aa54295d"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:180634ccb7c5f123707d69b9"
] | [] | [] | {"qa_id":"QA:b1cbef4c51a5e692d18fbe8d","qa_group_id":"QAG:64434a1291a93029602f29fb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Using a murine model of mCRC that retained these findings from hum... |
QA:b2341a3b586984693dda6e33 | QAG:3f72eb991d36929625342d8d | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In addition, the number of MDSCs in peripheral blood of CRC patients with metastasis was higher than that of patients without metastasis (Fig. 2D )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: retur... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d486c11c86f5d00ce43ab21e","quotes":["In addition, the number of MDSCs in peripheral blood of CRC patients with me... | [
"CLM:d486c11c86f5d00ce43ab21e",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8119947"
] | [
"SPAN:408e9117985ebb2011c97774"
] | [] | [] | {"qa_id":"QA:b2341a3b586984693dda6e33","qa_group_id":"QAG:3f72eb991d36929625342d8d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In addition, the number of MDSCs in peripheral blood of CRC patien... |
QA:b585773827c5cbb1aee7bb66 | QAG:6febe46d33a4f5eb228a0914 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Using a murine model of mCRC that recapitulates these findings from human disease, we showed that targeting CCR2 reduces TAM accumulation in liver metastasis and restores anti-tumor immunity"? Return the original wording with paper, Claim, and Evidence Span references.... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7eaa0c4a2371ad942f291275","quotes":["Using a murine model of mCRC that recapitulates these findings from human di... | [
"CLM:7eaa0c4a2371ad942f291275",
"CLM:04bbc50258758972aa54295d"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:180634ccb7c5f123707d69b9"
] | [] | [] | {"qa_id":"QA:b585773827c5cbb1aee7bb66","qa_group_id":"QAG:6febe46d33a4f5eb228a0914","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Using a murine model of mCRC that recapitulates these findings fro... |
QA:b5b75658a594c74aa4d23267 | QAG:ec942062927d2778e2818700 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Given that TCF4 expression was correlated with TAMs numbers and M2 macrophage-associated gene expression in human CRC samples, we sought to validate the regulating role of TCF4 in macrophage recruitment and polarization"? Return the original wording with paper, Claim, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4fdd83c9cfee33fc6576fb90","quotes":["Given that TCF4 expression was correlated with TAMs numbers and M2 macrophag... | [
"CLM:4fdd83c9cfee33fc6576fb90",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:04cf715fbf785146c4081d55"
] | [] | [] | {"qa_id":"QA:b5b75658a594c74aa4d23267","qa_group_id":"QAG:ec942062927d2778e2818700","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Given that TCF4 expression was correlated with TAMs numbers and M2... |
QA:b7e4db1d7d558626d748e456 | QAG:23d537092d0d09c80b6dce85 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Collectively, our findings suggest that STING is decreased in M2-like macrophages that are linked with liver metastasis in colorectal cancer"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the e... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8c004d1b2e28f4970d980c15","quotes":["Collectively, our findings suggest that STING is decreased in M2-like macrop... | [
"CLM:8c004d1b2e28f4970d980c15",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:2843947dbcec0ad1211d43e8"
] | [] | [] | {"qa_id":"QA:b7e4db1d7d558626d748e456","qa_group_id":"QAG:23d537092d0d09c80b6dce85","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Collectively, our findings suggest that STING is decreased in M2-l... |
QA:bbaf833a6585d5a700d8b524 | QAG:fd56ca3a825954174d0c6bb8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The combination of CHSY1 knockdown and anti-PD1 led to synergistic resistance against liver metastasis in CRC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with pa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2f18a10139e57fbed1497590","quotes":["Fig. 9 Pattern diagram showing that CHSY1 could pro... | [
"CLM:2f18a10139e57fbed1497590",
"CLM:71ac756b9724a4423f9240ec",
"CLM:f10b00e03249f6ce269e1eb0",
"CLM:06ac56904fbab2322b5096d2",
"CLM:5f3de0969066f18485561a7f"
] | [
"PMCID:PMC10519095",
"PMCID:PMC8990480",
"PMCID:PMC6700499"
] | [
"SPAN:7f4de2ae1e00288fea01f48f",
"SPAN:84bf9aff324fa321ccc4186e",
"SPAN:655f9290a733cb8520c27068",
"SPAN:c0c5cb5b1045c15be72b7400"
] | [
"ASC2:b7e722755206e4d6fccd36d0",
"ASC2:2b9f20ef817c11994396db29"
] | [
"HYP:DCH:d305e46c2af4014a85872938"
] | {"qa_id":"QA:bbaf833a6585d5a700d8b524","qa_group_id":"QAG:fd56ca3a825954174d0c6bb8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The combination of CHSY1 knockdown and anti-PD1 led to synergistic... |
QA:bc50bb7e648cc1fbd63e0728 | QAG:d045009738b235dc8f073d93 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "We then demonstrated at the cellular level that CHSY1 led to CD8 + T cell depletion through activation of succinate metabolism and PI3K/AKT/HIF1A pathway in CRC liver metastases"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7eeff011d0f24e24ba23357f","quotes":["We then demonstrated at the cellular level that CHSY1 leads to CD8 + T cell ... | [
"CLM:7eeff011d0f24e24ba23357f",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:c19f9e0365ec4beb5e873993"
] | [] | [] | {"qa_id":"QA:bc50bb7e648cc1fbd63e0728","qa_group_id":"QAG:d045009738b235dc8f073d93","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"We then demonstrated at the cellular level that CHSY1 led to CD8 +... |
QA:bc88c1ef2721e609cc8ca62c | QAG:f6a3c534bfcb8987c521c0b7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "CX3CR1 expression was increased in poorly differentiated colon carcinoma, which was much higher than that of moderately differentiated or well-differentiated colon carcinoma (Figure 1 A)"? Return the original wording with paper, Claim, and Evidence Span references.
In... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:210e9d1e1a5ea7058d1c4e18","quotes":["CX3CR1 expression was significantly elevated in poorly differentiated colon ... | [
"CLM:210e9d1e1a5ea7058d1c4e18",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC4176124"
] | [
"SPAN:5d1a17e54a16655a78c82fd4"
] | [] | [] | {"qa_id":"QA:bc88c1ef2721e609cc8ca62c","qa_group_id":"QAG:f6a3c534bfcb8987c521c0b7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"CX3CR1 expression was increased in poorly differentiated colon car... |
QA:bc890fc688937e4a2adcbab6 | QAG:2aed076c724b1f94fd9a2847 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "13 , 14 This investigation aimed to analyze the molecular mechanism and function of STING in liver metastasis promoted by colorectal cancer cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5f8ac0848173fe7b8633028e","quotes":["13 , 14 This investigation aimed to analyze the molecular mechanism and func... | [
"CLM:5f8ac0848173fe7b8633028e",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:875e2683a72c072386dca2eb"
] | [] | [] | {"qa_id":"QA:bc890fc688937e4a2adcbab6","qa_group_id":"QAG:2aed076c724b1f94fd9a2847","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"13 , 14 This investigation aimed to analyze the molecular mechanis... |
QA:bd708225d8958e7f989ff38e | QAG:ad6a0fd58be155d4db179202 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "This was mainly due to improved chemotherapy, the implementation of targeted therapies (VEGF and EGFR inhibitors ) and improvements in surgical management (resection of liver metastases)"? Return the original wording with paper, Claim, and Evidence Span references.
In... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:74ee69e502dbb2053e0f5fb5","quotes":["This was mainly due to improved chemotherapy, the implementation of targeted... | [
"CLM:74ee69e502dbb2053e0f5fb5",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6700499"
] | [
"SPAN:3243eddaebf6b2f32dbbd302",
"SPAN:5d98a7a0a980a75e5b579ce5"
] | [] | [] | {"qa_id":"QA:bd708225d8958e7f989ff38e","qa_group_id":"QAG:ad6a0fd58be155d4db179202","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"This was mainly due to improved chemotherapy, the implementation o... |
QA:c1a0dd3a866fba8bd292814d | QAG:ab70e0943dfc8bd714d925b3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Although good prognosis has been achieved in patients with early-stage CRC due to the advances in surgical and medical therapies, approximately 40% of patients with CRC progress to fatal metastasis"? Return the original wording with paper, Claim, and Evidence Span refe... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b8229bae067a17262737bab0","quotes":["Although good prognosis has been achieved in patients with early-stage CRC d... | [
"CLM:b8229bae067a17262737bab0",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC10030919"
] | [
"SPAN:d01cb85ec1bfcb13567b0d2f"
] | [] | [] | {"qa_id":"QA:c1a0dd3a866fba8bd292814d","qa_group_id":"QAG:ab70e0943dfc8bd714d925b3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Although good prognosis has been achieved in patients with early-s... |
QA:c24d1944ba75641b603b4f18 | QAG:e54df1402b8bc894987f7fea | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "c A wound healing assay showed S1PR1 overexpression promoted cell migration of SW480 and S1PR1 knockdown significantly inhibited the migration of HCT116, 36 h after wounding. d A transwell assay showed S1PR1 overexpression significantly promoted cell migration and inva... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aea39ffa0d12c44d0a9cc21d","quotes":["Fig. 2 S1PR1 promote CRC cell proliferation, invasion, migration and liver m... | [
"CLM:aea39ffa0d12c44d0a9cc21d",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:7a8eac19041000316563bf1a"
] | [] | [] | {"qa_id":"QA:c24d1944ba75641b603b4f18","qa_group_id":"QAG:e54df1402b8bc894987f7fea","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"c A wound healing assay showed S1PR1 overexpression promoted cell ... |
QA:c2603d10d61386b7c3d0166c | QAG:8d8642650d04a68b35bdeace | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In CRC, B-cell frequency decreased in tumor tissue compared to peritumor tissue"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8b8d3ee5da17a145de7f8e7f","quotes":["In CRC, B-cell frequency decreased in tumor tissue compared to peritumor tis... | [
"CLM:8b8d3ee5da17a145de7f8e7f",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10964083"
] | [
"SPAN:209c4da525041f0d64647503"
] | [] | [] | {"qa_id":"QA:c2603d10d61386b7c3d0166c","qa_group_id":"QAG:8d8642650d04a68b35bdeace","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In CRC, B-cell frequency decreased in tumor tissue compared to per... |
QA:c2dfbcc62a612e7f4bbef826 | QAG:438d3ec9242ab4b507f6c6b7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Furthermore, Pearson’s correlation analysis indicated that TCF4 mRNA expression was correlated with CCL2 mRNA expression in human CRC samples"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b4e7a5bb4752fee044063946","quotes":["Furthermore, Pearson’s correlation analysis indicated that TCF4 mRNA express... | [
"CLM:b4e7a5bb4752fee044063946",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:559ca54a0929c65541e45612"
] | [] | [] | {"qa_id":"QA:c2dfbcc62a612e7f4bbef826","qa_group_id":"QAG:438d3ec9242ab4b507f6c6b7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Furthermore, Pearson’s correlation analysis indicated that TCF4 mR... |
QA:c4845d672a3de7a44e304877 | QAG:6fedbf41d7de418960fe2bd7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Mice with liver metastases of colorectal cancer received OI (OI can be converted into intracellular itaconic acid by macrophages in vivo ) for three consecutive weeks"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:66959a29575abecff722d612","quotes":["Mice with liver metastases of colorectal cancer were treated with OI (OI can... | [
"CLM:66959a29575abecff722d612",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:b7d450bdd4571f13c4cb962b"
] | [] | [] | {"qa_id":"QA:c4845d672a3de7a44e304877","qa_group_id":"QAG:6fedbf41d7de418960fe2bd7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Mice with liver metastases of colorectal cancer received OI (OI ca... |
QA:c4d5d5f62cbad2ff31bbc0d0 | QAG:ae6764c7ff1d6005365736ec | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Additionally, the STING agonist DMXAA and cGAMP-treated groups inhibited CRC cells' migratory and invasive abilities without any remarkable effect on proliferation ( Figures S1 B and S1C)"? Return the original wording with paper, Claim, and Evidence Span references.
I... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:863e6c5ed5761f1c74bd40d0","quotes":["Additionally, the STING agonist DMXAA and cGAMP-treated groups significantly... | [
"CLM:863e6c5ed5761f1c74bd40d0",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:e1d9e71ddd9843a62b121c3a"
] | [] | [] | {"qa_id":"QA:c4d5d5f62cbad2ff31bbc0d0","qa_group_id":"QAG:ae6764c7ff1d6005365736ec","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Additionally, the STING agonist DMXAA and cGAMP-treated groups inh... |
QA:c8ab5cef252de0d6a85688a4 | QAG:8428abaf6836aacf3363ecb2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "It has been reported that CIC promoted by short-term DSS feeding causes colorectal tumor formation in Apc +/min mice ( 24 )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:52d6aa5950513cb157bb5831","quotes":["It has been reported that CIC induced by short-term DSS feeding causes color... | [
"CLM:52d6aa5950513cb157bb5831",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7474657"
] | [
"SPAN:9ad3d946844f5d4eef6b5a0a",
"SPAN:dc934c0665298244d352e07d"
] | [] | [] | {"qa_id":"QA:c8ab5cef252de0d6a85688a4","qa_group_id":"QAG:8428abaf6836aacf3363ecb2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"It has been reported that CIC promoted by short-term DSS feeding c... |
QA:c9da27b1b38c94396c10463a | QAG:550e0f50e34905a3ff994aa4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Mice with MC38 colon cancer mice were divided into four groups: the control group, which received an isotype control antibody; the MWA group, which was treated with MWA and an isotype control antibody; the TIGIT group, which was treated with anti-TIGIT; and the MWA plu... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:04bbc50258758972aa54295d","quotes":["Mice with MC38 colon cancer mice were divided into four groups: the control ... | [
"CLM:04bbc50258758972aa54295d",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8935077"
] | [
"SPAN:10ad293173c9e8cb099e8c12"
] | [] | [] | {"qa_id":"QA:c9da27b1b38c94396c10463a","qa_group_id":"QAG:550e0f50e34905a3ff994aa4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Mice with MC38 colon cancer mice were divided into four groups: th... |
QA:caeef82cd5d312a22c35852c | QAG:16244845557926209d26d207 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "To investigate the potential function of IRG1 activation in tumor metastasis, we promoted M2-like macrophages in vitro and assessed their effects on CRC through transwell assays"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9944aa57dc968881263a9fed","quotes":["To investigate the potential function of IRG1 activation in tumor metastasis... | [
"CLM:9944aa57dc968881263a9fed",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:b6e41f4c76b87c66bc6da6ab"
] | [] | [] | {"qa_id":"QA:caeef82cd5d312a22c35852c","qa_group_id":"QAG:16244845557926209d26d207","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To investigate the potential function of IRG1 activation in tumor ... |
QA:cb0607cb779805232f4168c8 | QAG:34de019667d3fce937aede65 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "6% (108/153) of the CRC primary lesions and was correlated with metachronous liver metastasis 10"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, a... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9837ed5c5b2ac9b19af707b4","quotes":["Previously, we reported that the expression of S1PR1 was significantly upreg... | [
"CLM:9837ed5c5b2ac9b19af707b4",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:731ce999a17428028c4f2548"
] | [] | [] | {"qa_id":"QA:cb0607cb779805232f4168c8","qa_group_id":"QAG:34de019667d3fce937aede65","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"6% (108/153) of the CRC primary lesions and was correlated with me... |
QA:cb42ce36bb70b39e74ad9265 | QAG:f12c2bbeb27a99cdd9028f14 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "To investigate the effects of polarized macrophages on colorectal cancer cell metastasis, we promoted M1/M2 polarized macrophages in vitro"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:46b872c54a679e0dcbc546f1","quotes":["To investigate the effects of polarized macrophages on colorectal cancer cel... | [
"CLM:46b872c54a679e0dcbc546f1",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10405073"
] | [
"SPAN:f72bd01bf985a56b67d748ad"
] | [] | [] | {"qa_id":"QA:cb42ce36bb70b39e74ad9265","qa_group_id":"QAG:f12c2bbeb27a99cdd9028f14","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To investigate the effects of polarized macrophages on colorectal ... |
QA:cb7d25028a2838dc198dff7c | QAG:b79c946c82a4d1560aae5edb | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Using an inducible liver-specific transgenic model, we found that CCRK overexpression dramatically increased both B16F10 melanoma and MC38 colorectal cancer (CRC) metastasis to the liver, which was highly infiltrated by polymorphonuclear-myeloid-derived suppressor cell... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2df857d6b65f300dfd9de26f","quotes":["Using an inducible liver-specific transgenic model,... | [
"CLM:2df857d6b65f300dfd9de26f",
"CLM:7795cac80522afb92a0dc44d",
"CLM:4891a7c0d6427195517519ed"
] | [
"PMCID:PMC8115036",
"PMCID:PMC8476489"
] | [
"SPAN:0b157d14609081ff7e24f718",
"SPAN:8853cb87685c2426261ccbf8"
] | [
"ASC2:292f6d7c7237631afd7203f5"
] | [
"HYP:DCH:dec9291bd60ce51c66ee158d"
] | {"qa_id":"QA:cb7d25028a2838dc198dff7c","qa_group_id":"QAG:b79c946c82a4d1560aae5edb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Using an inducible liver-specific transgenic model, we found that ... |
QA:cb886c6476aa5969bd76def9 | QAG:cce9e1c1a065d76f17e8eb94 | provenance_qa | paper_evidence_availability | provenance_qa | G013 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC5718006? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC5718006","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC5718006"
] | [] | [] | [] | {"qa_id":"QA:cb886c6476aa5969bd76def9","qa_group_id":"QAG:cce9e1c1a065d76f17e8eb94","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G013","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC5718006... |
QA:cc9396fb82cb9c7fd9eeff2a | QAG:d81f775ef452948d86538c69 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "reported that CHSY1 was associated with poorer prognosis in human CRC, but no one has studied the function and mechanism of CHSY1 in cancer in depth"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: retu... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6958b27a0b5919de56314e0c","quotes":["Wu et al.[ 27 ] reported that CHSY1 was associated with poorer prognosis in ... | [
"CLM:6958b27a0b5919de56314e0c",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:ac600f3e839ea57ae56a6fea"
] | [] | [] | {"qa_id":"QA:cc9396fb82cb9c7fd9eeff2a","qa_group_id":"QAG:d81f775ef452948d86538c69","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"reported that CHSY1 was associated with poorer prognosis in human ... |
QA:cd47a435a689c5c2d4ce418b | QAG:6d3c0d5140467afd2d93820f | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Consistent with the above results, the expression levels of M2 markers were also increased in human bone marrow-derived macrophages (HBMDMs) treated with exosomes derived from CRC cells with high miR-934 expression compared with those in HBMDMs derived from CRC cells w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f72330d1576b76c3b62117e9","quotes":["Consistent with the above results, the expression levels of M2 markers were ... | [
"CLM:f72330d1576b76c3b62117e9",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:158ff3a3d103acf4b9ad2e29"
] | [] | [] | {"qa_id":"QA:cd47a435a689c5c2d4ce418b","qa_group_id":"QAG:6d3c0d5140467afd2d93820f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Consistent with the above results, the expression levels of M2 mar... |
QA:ce1e3818b37e2eeeafef1d0a | QAG:d25101a1efb6f84802f7d2f1 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The level of serum MIC-1 was higher than patients with colon carcinoma and old age (B), depth of tumor invasion (C) and remote metastasis (D)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:857e74eac83edce9e93b49ac","quotes":["The level of serum MIC-1 was significantly higher in patients with colon car... | [
"CLM:857e74eac83edce9e93b49ac",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC5421897"
] | [
"SPAN:49884449fd32c650f2980e7b"
] | [] | [] | {"qa_id":"QA:ce1e3818b37e2eeeafef1d0a","qa_group_id":"QAG:d25101a1efb6f84802f7d2f1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The level of serum MIC-1 was higher than patients with colon carci... |
QA:d27b26c6e585f38db2fda5f8 | QAG:fb341e18f155560fcd89d407 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Of the 92 paired clinical specimens, IL-9 protein and mRNA levels showed markedly decreased amounts in colon cancer samples compared with adjacent noncancerous specimens"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenan... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dcd775bf8682436d7ed80abe","quotes":["Of the 92 paired clinical specimens, IL-9 protein and mRNA levels showed mar... | [
"CLM:dcd775bf8682436d7ed80abe",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC6598323"
] | [
"SPAN:4fdeddf0307e7fea77cfaa6a"
] | [] | [] | {"qa_id":"QA:d27b26c6e585f38db2fda5f8","qa_group_id":"QAG:fb341e18f155560fcd89d407","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Of the 92 paired clinical specimens, IL-9 protein and mRNA levels ... |
QA:d2dc2c99c33845a746633606 | QAG:680920f84a56fdecee964b21 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In addition, Spearman correlation analysis showed that the CD163-positive rate was associated with the miR-934 expression level in 50 CRC tissues (Additional file 3 : Fig. S3)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated pr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b4a7fc5d5c1728e91d136616","quotes":["In addition, Spearman correlation analysis showed that the CD163-positive ra... | [
"CLM:b4a7fc5d5c1728e91d136616",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:66d98054fe0df7c55f2c0359"
] | [] | [] | {"qa_id":"QA:d2dc2c99c33845a746633606","qa_group_id":"QAG:680920f84a56fdecee964b21","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In addition, Spearman correlation analysis showed that the CD163-p... |
QA:d5ee425ebe35031225a97c24 | QAG:8e7b8cc1a159cb897ea3d553 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The apoptosis assays suggested that coculturing with neutrophils decreased the apoptotic proportion of CRC cells, while this effect could be rescued by neutralization of CD80 and CD86 (Fig. 3E and Supplementary Fig. 8D )"? Return the original wording with paper, Claim,... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eda943982e4ecdf048b3992b","quotes":["The apoptosis assays suggested that coculturing with neutrophils attenuated ... | [
"CLM:eda943982e4ecdf048b3992b",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC9705377"
] | [
"SPAN:de1b3172693669f98fbf34b1"
] | [] | [] | {"qa_id":"QA:d5ee425ebe35031225a97c24","qa_group_id":"QAG:8e7b8cc1a159cb897ea3d553","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The apoptosis assays suggested that coculturing with neutrophils d... |
QA:d682babed00f22af5567c223 | QAG:dce7aabc5d1ecbeb9e05f75e | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "As shown above, IL-9 expression in colon carcinoma was correlated with TNM staging, Dukes staging, and LNM ( P < .05; Table 2 )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporti... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eecadd4a4f644daa37ed1cab","quotes":["As shown above, IL-9 expression in colon carcinoma was correlated with TNM s... | [
"CLM:eecadd4a4f644daa37ed1cab",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC6598323"
] | [
"SPAN:ebc8f2db3c0255b42a382f15"
] | [] | [] | {"qa_id":"QA:d682babed00f22af5567c223","qa_group_id":"QAG:dce7aabc5d1ecbeb9e05f75e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"As shown above, IL-9 expression in colon carcinoma was correlated ... |
QA:d6ed45cd302e5180f3b7edca | QAG:c63d29bdd5d0ecd9efa12582 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "(B) Macrophages’ specific deletion of SHP2 increased the fluorescent intensity of Tie2 in CD68/macrophages marker cells and the statistical data, scar bar: 50 μm. ** p < 0.01, SHP2MAC-KO mice vs"? Return the original wording with paper, Claim, and Evidence Span referen... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7002d59ab5d1af1e6d624bef","quotes":["(A) Macrophages’ specific deletion of SHP2 accelerated amounts of colorectal... | [
"CLM:7002d59ab5d1af1e6d624bef",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10207961"
] | [
"SPAN:752a5402c5fadc5da0b989a2"
] | [] | [] | {"qa_id":"QA:d6ed45cd302e5180f3b7edca","qa_group_id":"QAG:c63d29bdd5d0ecd9efa12582","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"(B) Macrophages’ specific deletion of SHP2 increased the fluoresce... |
QA:d889a7d8c21c8e976c9b9099 | QAG:b7dbad986f6f1c0f069de77c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Figure 5 PAD2-IN-1 inhibited METs formation and colon cancer liver metastasis in vivo"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bb34283f96d3267bdaa30cfc","quotes":["Figure 5 PAD2-IN-1 inhibited METs formation and colon cancer liver metastasi... | [
"CLM:bb34283f96d3267bdaa30cfc",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8671452"
] | [
"SPAN:ff8d01bcad222108af284a60"
] | [] | [] | {"qa_id":"QA:d889a7d8c21c8e976c9b9099","qa_group_id":"QAG:b7dbad986f6f1c0f069de77c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Figure 5 PAD2-IN-1 inhibited METs formation and colon cancer liver... |
QA:dbe2462a61e36fb06e712281 | QAG:8074c0fbc11581a8099f2824 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Then, we verified that CRC cell-derived exosomal miR-934 promoted M2 macrophage polarization by downregulating PTEN expression and activating the PI3K/AKT signaling pathway"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated prove... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:11b6f95fd25edf270388a4d7","quotes":["Then, we verified that CRC cell-derived exosomal miR-934 induced M2 macropha... | [
"CLM:11b6f95fd25edf270388a4d7",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:183cf6a7571e588e15e1d618"
] | [] | [] | {"qa_id":"QA:dbe2462a61e36fb06e712281","qa_group_id":"QAG:8074c0fbc11581a8099f2824","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Then, we verified that CRC cell-derived exosomal miR-934 promoted ... |
QA:dd1eba281279855bb5a344be | QAG:71a32888bf2045c4be572fad | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Notably, Olguín et al ( 29 ) discovered that the percentage of CD4 + FOXP3 + Tregs was increased in colitis-associated colon cancer"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supp... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d7d70e1cb2c4d6ab3f21f315","quotes":["Notably, Olguín et al ( 29 ) discovered that the percentage of CD4 + FOXP3 +... | [
"CLM:d7d70e1cb2c4d6ab3f21f315",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7400973"
] | [
"SPAN:fdc1c027f882ad20490a3a1e"
] | [] | [] | {"qa_id":"QA:dd1eba281279855bb5a344be","qa_group_id":"QAG:71a32888bf2045c4be572fad","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Notably, Olguín et al ( 29 ) discovered that the percentage of CD4... |
QA:deeee2d55017945a658b190b | QAG:dddc25aac7c364b1ba0806a2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The down-regulated expression of CHSY1 in the sh-CHSY1 group inhibited the liver metastasis of CRC compared to the sh-NC group (Fig. 5 B-C)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ex... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c97bd5820291f8024d304a4a","quotes":["The down-regulated expression of CHSY1 in the sh-CHSY1 group significantly i... | [
"CLM:c97bd5820291f8024d304a4a",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:6c5cef1a4170d764353fdba5"
] | [] | [] | {"qa_id":"QA:deeee2d55017945a658b190b","qa_group_id":"QAG:dddc25aac7c364b1ba0806a2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The down-regulated expression of CHSY1 in the sh-CHSY1 group inhib... |
QA:e07bc54fc01b6e372dc6daf4 | QAG:b5ae93c01c7510254b43b08d | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Neutrophil/lymphocyte ratio predicted chemotherapy outcomes in patients with advanced colorectal cancer"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, C... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bced5a7e3b1cc9e059ab812c","quotes":["43. Chua W., Charles K. A., Baracos V. E., Clarke S. J., Neutrophil/lymphocy... | [
"CLM:bced5a7e3b1cc9e059ab812c",
"CLM:32074368e9eaad5d6640b1f3"
] | [
"PMCID:PMC7474657"
] | [
"SPAN:4493081d6d139f9e39bc85fd"
] | [] | [] | {"qa_id":"QA:e07bc54fc01b6e372dc6daf4","qa_group_id":"QAG:b5ae93c01c7510254b43b08d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Neutrophil/lymphocyte ratio predicted chemotherapy outcomes in pat... |
QA:e0aae206b9388120c216706e | QAG:68c0e9d09ff24ad799ec4adf | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Moreover, higher levels of CCL15 in the primary CRC was associated with abundance of CCR1 + cells recruited to the metastatic foci, and with shorter disease-free survival"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provena... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9af4db9a09236e02fe0651c6","quotes":["Moreover, higher levels of CCL15 in the primary CRC are associated with abun... | [
"CLM:9af4db9a09236e02fe0651c6",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC4256518"
] | [
"SPAN:8169970e6045d73905d45c87"
] | [] | [] | {"qa_id":"QA:e0aae206b9388120c216706e","qa_group_id":"QAG:68c0e9d09ff24ad799ec4adf","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Moreover, higher levels of CCL15 in the primary CRC was associated... |
QA:e5eb207e0801bb8d8e89c910 | QAG:43f318f2dbbde9cd3d8c5d38 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The panel with the MIC-1 and CEA achieved by the logistic regression model demonstrates high diagnostic accuracy (AUC=0.897; sensitivity=82%; specificity=89%) in differencing CRC from healthy controls"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6a34b6020ae9ce03b01b43b8","quotes":["The panel with the MIC-1 and CEA achieved by the logistic regression model d... | [
"CLM:6a34b6020ae9ce03b01b43b8",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC5421897"
] | [
"SPAN:8b6b242ad42e1aeecf293137"
] | [] | [] | {"qa_id":"QA:e5eb207e0801bb8d8e89c910","qa_group_id":"QAG:43f318f2dbbde9cd3d8c5d38","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The panel with the MIC-1 and CEA achieved by the logistic regressi... |
QA:e6c3d47c301692510ca43c93 | QAG:65372a1be1194831c5221b3f | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "found that in MSI (Microsatellite instability)-H CRC patients benefiting from pembrolizumab immunotherapy, tumor infiltrating CD4 + and CD8 + T cells was higher than those of MSS (microsatellite stable) CRC"? Return the original wording with paper, Claim, and Evidence ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fb5daaeff9e0fd119348fbb9","quotes":["De Smedt et al. [ 38 ] found that in MSI (Microsatellite instability)-H CRC ... | [
"CLM:fb5daaeff9e0fd119348fbb9",
"CLM:32074368e9eaad5d6640b1f3"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:7dda229dc761c69a6e03f429"
] | [] | [] | {"qa_id":"QA:e6c3d47c301692510ca43c93","qa_group_id":"QAG:65372a1be1194831c5221b3f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"found that in MSI (Microsatellite instability)-H CRC patients bene... |
QA:e6fdbc8d668c4b7755b4819f | QAG:fafa23e358a932f55df65499 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Blockade of TCF4-CCL2-CCR2 axis inhibited CRC hepatic metastasis through inhibiting TAMs accumulation and M2 polarization in the tumor microenvironment"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4b7ba67ce79b14d4b1b0142b","quotes":["Blockade of TCF4-CCL2-CCR2 axis significantly suppressed CRC hepatic metasta... | [
"CLM:4b7ba67ce79b14d4b1b0142b",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:e303a17f5a4717f506b3eb45"
] | [] | [] | {"qa_id":"QA:e6fdbc8d668c4b7755b4819f","qa_group_id":"QAG:fafa23e358a932f55df65499","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Blockade of TCF4-CCL2-CCR2 axis inhibited CRC hepatic metastasis t... |
QA:e84015a4dbe95cb3a1619d05 | QAG:a5aaf2d80ffa8d9cb5900483 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "b S1PR1 overexpression promoted the growth of SW480 and S1PR1 knockdown significantly inhibited the growth of HCT116, as revealed using an MTT assay. c A wound healing assay showed S1PR1 overexpression significantly promoted cell migration of SW480 and S1PR1 knockdown ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b24eadd6f16a597733e25d9b","quotes":["Fig. 2 S1PR1 promote CRC cell proliferation, invasion, migration and liver m... | [
"CLM:b24eadd6f16a597733e25d9b",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:7a8eac19041000316563bf1a"
] | [] | [] | {"qa_id":"QA:e84015a4dbe95cb3a1619d05","qa_group_id":"QAG:a5aaf2d80ffa8d9cb5900483","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"b S1PR1 overexpression promoted the growth of SW480 and S1PR1 knoc... |
QA:e8470502127e0fec2f367e24 | QAG:50d3cb747a906a80e1282a2b | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Additional quantitative analysis of hepatic metastatic tumor burden and treatment efficacy found that administration of a small molecule CCR2 inhibitor (CCR2i) improved chemotherapeutic responses and increases overall survival in mice with mCRC liver tumors"? Return th... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5aae2566eab4ff18d1a11062","quotes":["Additional quantitative analysis of hepatic metastatic tumor burden and trea... | [
"CLM:5aae2566eab4ff18d1a11062",
"CLM:0956beeb5c637a6f28998add"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:7c851d5c29142b3654d9a344"
] | [] | [] | {"qa_id":"QA:e8470502127e0fec2f367e24","qa_group_id":"QAG:50d3cb747a906a80e1282a2b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Additional quantitative analysis of hepatic metastatic tumor burde... |
QA:ea07428faede1973e84b354c | QAG:2f1f8206c158964ad76dd065 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "1 TCF4 expression is increased in colorectal cancer hepatic metastasis compared with the primary site and is correlated with tumor-associated macrophage recruitment in the tumor area"? Return the original wording with paper, Claim, and Evidence Span references.
Integr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eca7a21b18a5a60d053465fb","quotes":["Fig. 1 TCF4 expression is elevated in colorectal cancer hepatic metastasis c... | [
"CLM:eca7a21b18a5a60d053465fb",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:d38e2754eade644eba19bae4"
] | [] | [] | {"qa_id":"QA:ea07428faede1973e84b354c","qa_group_id":"QAG:2f1f8206c158964ad76dd065","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"1 TCF4 expression is increased in colorectal cancer hepatic metast... |
QA:ea78fcc2c779fb38f51f58dd | QAG:711cebbf8ff22263d8c5d63c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The primary and secondary lesions and corresponding paracancerous tissues of four patients with CRC liver metastases were first detected by immunofluorescence, and the results showed that CHSY1 expression in cancer tissues was higher than that in paracancerous tissues"... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:839ff50e1071562aa7ac6710","quotes":["The primary and secondary lesions and corresponding paracancerous tissues of... | [
"CLM:839ff50e1071562aa7ac6710",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:c555f4f2735929d953246f44"
] | [] | [] | {"qa_id":"QA:ea78fcc2c779fb38f51f58dd","qa_group_id":"QAG:711cebbf8ff22263d8c5d63c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The primary and secondary lesions and corresponding paracancerous ... |
QA:eb40cd8ea27cdb03d25339bd | QAG:c537f7083e6926d2dbef297c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Eventually, we tested the expression of SHP-2 in tumor-associated macrophages and the results showed that SHP-2 expression was increased in human CRC tissues vs . human normal colonic tissue, which is consistent with previous studies of Wenbin Chen’s previous studies"?... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0d6a6eb88d3f3cf1730b12a1","quotes":["Eventually, we tested the expression of SHP-2 in tumor-associated macrophage... | [
"CLM:0d6a6eb88d3f3cf1730b12a1",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10207961"
] | [
"SPAN:86f813d5df6f3bb321d3a473"
] | [] | [] | {"qa_id":"QA:eb40cd8ea27cdb03d25339bd","qa_group_id":"QAG:c537f7083e6926d2dbef297c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Eventually, we tested the expression of SHP-2 in tumor-associated ... |
QA:eb73a7dbe2f5de3d9cc922cc | QAG:7f4d675e03105671d3a7d23c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "2 Depletion of macrophage in the liver decreased colorectal cancer liver metastasis in the mouse model"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Cl... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eaca21f08ec330ad013e45ae","quotes":["Fig. 2 Depletion of macrophage in the liver attenuated colorectal cancer liv... | [
"CLM:eaca21f08ec330ad013e45ae",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:5b7ef100bf499ccd9fcadfb9"
] | [] | [] | {"qa_id":"QA:eb73a7dbe2f5de3d9cc922cc","qa_group_id":"QAG:7f4d675e03105671d3a7d23c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"2 Depletion of macrophage in the liver decreased colorectal cancer... |
QA:ecbab5c0d6d4c61fdd4cccec | QAG:465f487f44f9e14635d3b8a1 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In the present study, we demonstrated that the M2 polarization of macrophages induced by CRC cell-derived exosomal miR-934 could promote CRLM via a CXCL13/CXCR5/NFκB/p65 positive feedback loop, which led to persistent crosstalk between tumor cells and TAMs, forming an ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:adf3568c44312ee2d9c4a575","quotes":["In the present study, we demonstrated that the M2 polarization of macrophage... | [
"CLM:adf3568c44312ee2d9c4a575",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:e36b9a63c885ac1afc20ae9d"
] | [] | [] | {"qa_id":"QA:ecbab5c0d6d4c61fdd4cccec","qa_group_id":"QAG:465f487f44f9e14635d3b8a1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In the present study, we demonstrated that the M2 polarization of ... |
QA:ed585e4cdd510f82067d09b4 | QAG:b12ec51f3f9aeff3ce344f51 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The metabolomic analysis indicated that CHSY1 promoted CD8 + T cell exhaustion by activating the succinate metabolism pathway leading to liver metastasis of CRC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requir... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0cf5e6426400b3cf6bc3d93d","quotes":["The metabolomic analysis indicated that CHSY1 promoted CD8 + T cell exhausti... | [
"CLM:0cf5e6426400b3cf6bc3d93d",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:9a112fc7007845dc311c1e9a"
] | [] | [] | {"qa_id":"QA:ed585e4cdd510f82067d09b4","qa_group_id":"QAG:b12ec51f3f9aeff3ce344f51","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The metabolomic analysis indicated that CHSY1 promoted CD8 + T cel... |
QA:ee78e6b34e715a452325b16a | QAG:8aa46b1a9f693e772d14d621 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "To examine the effect of MGP on the microenvironment of CRC, the correlation between MGP expression and immune factors was predicted using the TISIDB database"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirem... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6e29e1feb4e391bd90209205","quotes":["To examine the effect of MGP on the microenvironment of CRC, the correlation... | [
"CLM:6e29e1feb4e391bd90209205",
"CLM:32074368e9eaad5d6640b1f3"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:7129254e58956468d906ae3e"
] | [] | [] | {"qa_id":"QA:ee78e6b34e715a452325b16a","qa_group_id":"QAG:8aa46b1a9f693e772d14d621","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"To examine the effect of MGP on the microenvironment of CRC, the c... |
QA:f049b6b2ec60206cf0e499bb | QAG:f73a092a22d9244c3e37bcc4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "the TIGIT group, which received anti-TIGIT; and the MWA plus TIGIT group, which was treated with MWA and anti-TIGIT"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ec6d2b52a26e008d3d495b09","quotes":["Mice with MC38 colon cancer mice were divided into four groups: the control ... | [
"CLM:ec6d2b52a26e008d3d495b09",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8935077"
] | [
"SPAN:10ad293173c9e8cb099e8c12"
] | [] | [] | {"qa_id":"QA:f049b6b2ec60206cf0e499bb","qa_group_id":"QAG:f73a092a22d9244c3e37bcc4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"the TIGIT group, which received anti-TIGIT; and the MWA plus TIGIT... |
QA:f0b5ed8f5d656626ce845571 | QAG:53d11f66d2d36591d16b3617 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "CRC incidence and mortality rates are increasing over time, and the global burden of CRC has been predicted to increase by 60% to more than 1.1 million deaths and 2.2 million novel cases by 2030 3 , 4"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:09d1918be537ad5e2de9db39","quotes":["CRC incidence and mortality rates are increasing over time, and the global b... | [
"CLM:09d1918be537ad5e2de9db39",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:57d289f0f81fa33939c3879e"
] | [] | [] | {"qa_id":"QA:f0b5ed8f5d656626ce845571","qa_group_id":"QAG:53d11f66d2d36591d16b3617","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"CRC incidence and mortality rates are increasing over time, and th... |
QA:f0d70678d12a6befdfe5f23f | QAG:6410e743637481fb1825f8e0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "According to the results, the mRNA and protein expression of MGP in CRC tissues was increased compared with that in paracancerous normal tissues (Figure 1 F and 1 G)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:28c71a430873b4c687ca6b84","quotes":["According to the results, the mRNA and protein expression of MGP in CRC tiss... | [
"CLM:28c71a430873b4c687ca6b84",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:80394f2ea7250898c5aa9730"
] | [] | [] | {"qa_id":"QA:f0d70678d12a6befdfe5f23f","qa_group_id":"QAG:6410e743637481fb1825f8e0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"According to the results, the mRNA and protein expression of MGP i... |
QA:f0ee70961036c4910ba79eec | QAG:de7eba3962f2c4253af67f1c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In vitro and in vivo experiments confirmed that CHSY1 facilitated the liver metastasis of CRC and CHSY1 promoted CD8 + T cell exhaustion and upregulated PD-L1 expression"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenan... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9b3d8a586c6de9a876eebbbc","quotes":["In vitro and in vivo experiments confirmed that CHSY1 facilitated the liver ... | [
"CLM:9b3d8a586c6de9a876eebbbc",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:a929d69ef634510060a528fb"
] | [] | [] | {"qa_id":"QA:f0ee70961036c4910ba79eec","qa_group_id":"QAG:de7eba3962f2c4253af67f1c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In vitro and in vivo experiments confirmed that CHSY1 facilitated ... |
QA:f2aabb734f62f97ce2f1dfe6 | QAG:c584fc38a90fb11e2231a118 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "According to the Kaplan-Meier survival curve, patients with CRC and high MGP expression had decreased overall survival (Figure 2 D), which was consistent with the TCGA database assessment (Figure 2 E)"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f4962cee1661f73497c93650","quotes":["According to the Kaplan-Meier survival curve, patients with CRC and high MGP... | [
"CLM:f4962cee1661f73497c93650",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:99c30caa7dda396fc7d8d58f"
] | [] | [] | {"qa_id":"QA:f2aabb734f62f97ce2f1dfe6","qa_group_id":"QAG:c584fc38a90fb11e2231a118","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"According to the Kaplan-Meier survival curve, patients with CRC an... |
QA:f2b27e1b5c76838e58ad685c | QAG:1479aece0b0e54e07d4d97ee | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Numerous studies have reported that the polarization of M2 macrophages promoted by tumor-derived exosomes can promote metastasis of CRC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1ac2aa67c74201b1e2c36ac3","quotes":["Numerous studies have reported that the polarization of M2 macrophages induc... | [
"CLM:1ac2aa67c74201b1e2c36ac3",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC7678301"
] | [
"SPAN:53f7beba8758100560de9963"
] | [] | [] | {"qa_id":"QA:f2b27e1b5c76838e58ad685c","qa_group_id":"QAG:1479aece0b0e54e07d4d97ee","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Numerous studies have reported that the polarization of M2 macroph... |
QA:f46f639e73e16b8af6ed3093 | QAG:db3b94845d7776b95e227e0a | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "4 Colorectal cancer (CRC) liver metastasis and hepatic Kupffer cell (KC) promoted by Proteus mirabilis or Bacteroides vulgatus"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supportin... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ee84b607d9851cd6c3e8c42b","quotes":["Fig. 4 Colorectal cancer (CRC) liver metastasis and hepatic Kupffer cell (KC... | [
"CLM:ee84b607d9851cd6c3e8c42b",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC9289841"
] | [
"SPAN:800f77a2ba3eb72d97410f9f"
] | [] | [] | {"qa_id":"QA:f46f639e73e16b8af6ed3093","qa_group_id":"QAG:db3b94845d7776b95e227e0a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"4 Colorectal cancer (CRC) liver metastasis and hepatic Kupffer cel... |
QA:f4cb6f0afda3482f397759cf | QAG:03111a78bd8bdf0a285c9ebc | provenance_qa | paper_evidence_availability | provenance_qa | G013 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9925731? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC9925731","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC9925731"
] | [] | [] | [] | {"qa_id":"QA:f4cb6f0afda3482f397759cf","qa_group_id":"QAG:03111a78bd8bdf0a285c9ebc","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G013","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9925731... |
QA:f6411527bcf4dd186e58f4c3 | QAG:7ab652ad6238d759c5dba709 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Significance Using mouse models that recapitulate key genetic abnormalities accumulating during colorectal cancer (CRC) tumorigenesis, we report that chemically promoted colitis promoted development of colon tumors that were largely resistant to anti-VEGF antibody trea... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e3b8b9c7f2e3994356fe11df","quotes":["Significance Using mouse models that recapitulate key genetic abnormalities ... | [
"CLM:e3b8b9c7f2e3994356fe11df",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC7474657"
] | [
"SPAN:1d742714f1e0c752258fb620"
] | [] | [] | {"qa_id":"QA:f6411527bcf4dd186e58f4c3","qa_group_id":"QAG:7ab652ad6238d759c5dba709","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Significance Using mouse models that recapitulate key genetic abno... |
QA:f6928d5854f8b725fb26b0aa | QAG:e0732f4c69c0e50d346d5611 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Immune monitoring of circulating monocytes in patients with mCRC found this influx was a prognostic biomarker and was correlated with worse clinical outcomes"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requireme... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0478df56bd5aa1173e674769","quotes":["Immune monitoring of circulating monocytes in patients with mCRC found this ... | [
"CLM:0478df56bd5aa1173e674769",
"CLM:04bbc50258758972aa54295d"
] | [
"PMCID:PMC6140580"
] | [
"SPAN:01120181c5878a4371913a1e"
] | [] | [] | {"qa_id":"QA:f6928d5854f8b725fb26b0aa","qa_group_id":"QAG:e0732f4c69c0e50d346d5611","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Immune monitoring of circulating monocytes in patients with mCRC f... |
QA:f730fac6a283040b0718ce55 | QAG:622ed592dbbba92a463d9a5e | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "However, transwell assay results showed that MC38 promoted KCs migration was attenuated by the CCL2 silencing in the MC38 cells (Fig. 6 F, G), which implied that CCL2 expression in the CRC cells was essential for KCs recruitment and polarization"? Return the original w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4891a7c0d6427195517519ed","quotes":["However, transwell assay results showed that MC38 induced KCs migration was ... | [
"CLM:4891a7c0d6427195517519ed",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:8853cb87685c2426261ccbf8"
] | [] | [] | {"qa_id":"QA:f730fac6a283040b0718ce55","qa_group_id":"QAG:622ed592dbbba92a463d9a5e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"However, transwell assay results showed that MC38 promoted KCs mig... |
QA:f7681ce1be1aeffd8c42dea7 | QAG:855e9f13ccc87342a9dbfce3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "d A transwell assay showed STAT3 knockdown inhibited cell migration and invasion of SW480-exS1PR1. e The morphologic characteristics of subcutaneous tumors in STAT3 knockdown SW480-exS1PR1 cells; characteristic images of liver metastases in STAT3 knockdown SW480-exS1PR... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3429f7b26e605af18c34a8dd","quotes":["Fig. 4 P-STAT3 is required for S1PR1-promoted tumor growth and liver metasta... | [
"CLM:3429f7b26e605af18c34a8dd",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:475f87c72c637abdf96962e9"
] | [] | [] | {"qa_id":"QA:f7681ce1be1aeffd8c42dea7","qa_group_id":"QAG:855e9f13ccc87342a9dbfce3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"d A transwell assay showed STAT3 knockdown inhibited cell migratio... |
QA:f987ac0f2275b40b0af03797 | QAG:e920407af1bf8845813d64f6 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In conclusion, SHP-2 in TEMs inhibited the activation or phosphorylated-Tie2 and consequently deactivated down-stream of PI3K-Akt-mTOR and resulted in the inhibited expression of angiogenic factor: VEGF, COX-2, MMPs, and eventually protect the tumor angiogenesis in CRC... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:39c3bcc02c7b2ea75e1b5f7b","quotes":["In conclusion, SHP-2 in TEMs suppressed the activation or phosphorylated-Tie... | [
"CLM:39c3bcc02c7b2ea75e1b5f7b",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10207961"
] | [
"SPAN:1f2918808a8e1e224ab1c16a"
] | [] | [] | {"qa_id":"QA:f987ac0f2275b40b0af03797","qa_group_id":"QAG:e920407af1bf8845813d64f6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In conclusion, SHP-2 in TEMs inhibited the activation or phosphory... |
QA:f9a2a5594af37d33b3e37f1f | QAG:e51ca0ff3e9229d1796a0b6c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Conclusions Our findings proposed that immunosuppressive microenvironment in liver induced by OXA increased liver metastasis of colorectal cancer, which highlighted a new consideration to balance the pro metastases and anti-cancer possibility of OXA treatment"? Return ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:32acf3db394f991181f7b4e7","quotes":["Conclusions Our findings proposed that immunosuppressive microenvironment in... | [
"CLM:32acf3db394f991181f7b4e7",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10494354"
] | [
"SPAN:d379856c6a38284a21f0a532"
] | [] | [] | {"qa_id":"QA:f9a2a5594af37d33b3e37f1f","qa_group_id":"QAG:e51ca0ff3e9229d1796a0b6c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Conclusions Our findings proposed that immunosuppressive microenvi... |
QA:f9d638d47eb4eddefbaa027d | QAG:b02e96012232d4565291c042 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Our previous study has shown that the metastasis of colon cancer cells in liver led to hepatocyte necrosis through energy deprivation but not only because of the space conflict"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9e401c2a6e1f3b8f524c11e8","quotes":["Our previous study has shown that the metastasis of colon cancer cells in li... | [
"CLM:9e401c2a6e1f3b8f524c11e8",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6378193"
] | [
"SPAN:5563d48f9b5b29dc6103794a"
] | [] | [] | {"qa_id":"QA:f9d638d47eb4eddefbaa027d","qa_group_id":"QAG:b02e96012232d4565291c042","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Our previous study has shown that the metastasis of colon cancer c... |
QA:fa713cb0a9b22ccfba4ffd5d | QAG:dff4ad62ec383dc72dd16452 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "c A wound healing assay showed STAT3 knockdown inhibited the migration of SW480-exS1PR1 cells, 36 h after wounding. d A transwell assay showed STAT3 knockdown significantly inhibited cell migration and invasion of SW480-exS1PR1. e The morphologic characteristics of sub... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:68c90abfa867f14f8edfbe8e","quotes":["Fig. 4 P-STAT3 is required for S1PR1-promoted tumor growth and liver metasta... | [
"CLM:68c90abfa867f14f8edfbe8e",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC6751205"
] | [
"SPAN:475f87c72c637abdf96962e9"
] | [] | [] | {"qa_id":"QA:fa713cb0a9b22ccfba4ffd5d","qa_group_id":"QAG:dff4ad62ec383dc72dd16452","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"c A wound healing assay showed STAT3 knockdown inhibited the migra... |
QA:fb2666ec5cdded836fee306e | QAG:83f28335c639bab002a8fbc7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "With the increase and improvement of clinical treatment methods, the long-term survival of metastatic CRC patients has been improved to a certain extent, but the five-year survival rate is still only a low 15%"? Return the original wording with paper, Claim, and Eviden... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4d5c4b6ac4d52b0bddb44e70","quotes":["With the increase and improvement of clinical treatment methods, the long-te... | [
"CLM:4d5c4b6ac4d52b0bddb44e70",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:ee6792dc1a7d41d1c278f2e6"
] | [] | [] | {"qa_id":"QA:fb2666ec5cdded836fee306e","qa_group_id":"QAG:83f28335c639bab002a8fbc7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"With the increase and improvement of clinical treatment methods, t... |
QA:fb387fc86a639d16763c4342 | QAG:afc5fce7a51b64d3a42bae35 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The results showed that increased expression of IL-33 in CRC cells enhanced their tumor take, growth, and liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting pa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:de3072d0c9f891507c698a9b","quotes":["The results showed that increased expression of IL-33 in CRC cells enhanced ... | [
"CLM:de3072d0c9f891507c698a9b",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC5630136"
] | [
"SPAN:d5a4bb47f36cabd492e85803"
] | [] | [] | {"qa_id":"QA:fb387fc86a639d16763c4342","qa_group_id":"QAG:afc5fce7a51b64d3a42bae35","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The results showed that increased expression of IL-33 in CRC cells... |
QA:fb4dd2bd3c0afaa8f5ed17e5 | QAG:fee250fd31fb5a19de319368 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "nucleatum have been reported to damage DNA, resulting in increased proliferation of colon cancer cells in studies on gut microbiota in cancer patients"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: re... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a4eb3f95af406a75becfd54e","quotes":["Certain metabolites secreted from Enterococcus faecalis or FadA in F. nuclea... | [
"CLM:a4eb3f95af406a75becfd54e",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8908934"
] | [
"SPAN:26d12c3436098fbb4d71ae67"
] | [] | [] | {"qa_id":"QA:fb4dd2bd3c0afaa8f5ed17e5","qa_group_id":"QAG:fee250fd31fb5a19de319368","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"nucleatum have been reported to damage DNA, resulting in increased... |
QA:fb5c9fb3fb0674065cb5ada7 | QAG:5c062fba7f8d7e867cf01f7a | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The downregulated expression of MGP in the sh-MGP group inhibited liver metastasis of CRC, compared with the sh-NC group"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting pass... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:64507962d309463ff165b047","quotes":["The downregulated expression of MGP in the sh-MGP group significantly inhibi... | [
"CLM:64507962d309463ff165b047",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8990480"
] | [
"SPAN:f8fce39029fb5200c55a6b99"
] | [] | [] | {"qa_id":"QA:fb5c9fb3fb0674065cb5ada7","qa_group_id":"QAG:5c062fba7f8d7e867cf01f7a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The downregulated expression of MGP in the sh-MGP group inhibited ... |
QA:fb853b07929b3654ec70bbaa | QAG:872caccc8b5920cbf3d76509 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "However, transwell assay results showed that MC38 induced KCs migration was decreased by the CCL2 silencing in the MC38 cells (Fig. 6 F, G), which implied that CCL2 expression in the CRC cells was essential for KCs recruitment and polarization"? Return the original wor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e93306bab6484481dbb024b4","quotes":["However, transwell assay results showed that MC38 induced KCs migration was ... | [
"CLM:e93306bab6484481dbb024b4",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC8476489"
] | [
"SPAN:8853cb87685c2426261ccbf8"
] | [] | [] | {"qa_id":"QA:fb853b07929b3654ec70bbaa","qa_group_id":"QAG:872caccc8b5920cbf3d76509","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"However, transwell assay results showed that MC38 induced KCs migr... |
QA:fbf090da7bea5cd49b16e438 | QAG:6d4afaa1563c338e61b26400 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "In the last two decades median overall survival of patients with metastatic CRC (mCRC) has increased from 18 up to 30 months"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:51ad2c1b6925578fe9d3d7ba","quotes":["In the last two decades median overall survival of patients with metastatic ... | [
"CLM:51ad2c1b6925578fe9d3d7ba",
"CLM:7795cac80522afb92a0dc44d"
] | [
"PMCID:PMC6700499"
] | [
"SPAN:3243eddaebf6b2f32dbbd302"
] | [] | [] | {"qa_id":"QA:fbf090da7bea5cd49b16e438","qa_group_id":"QAG:6d4afaa1563c338e61b26400","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"In the last two decades median overall survival of patients with m... |
QA:fc4e4bea96c321d546cd6693 | QAG:426cfd82252f46ba36a28c26 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "The above results suggest that CHSY1 led to CD8 + T cell exhaustion through activation of succinate metabolism and PI3K/AKT/HIF1A pathway in CRC liver metastasis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b1c0d5d80f11ac83f9d105dd","quotes":["The above results suggest that CHSY1 leads to CD8 + T cell exhaustion throug... | [
"CLM:b1c0d5d80f11ac83f9d105dd",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC10519095"
] | [
"SPAN:6fa6b429cbb6a8365ae705e3"
] | [] | [] | {"qa_id":"QA:fc4e4bea96c321d546cd6693","qa_group_id":"QAG:426cfd82252f46ba36a28c26","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"The above results suggest that CHSY1 led to CD8 + T cell exhaustio... |
QA:fce26d032c4b2ebded503673 | QAG:f71a481b592d72a2262ec3a9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "Accordingly, CRC liver metastasis patients exhibited hyperactivation of hepatic CCRK/NF-κB/CXCL1 signaling, which was associated with accumulation of PMN-MDSCs and paucity of NKT cells compared to healthy liver transplantation donors"? Return the original wording with ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:45ea64a716f53fb2edb6df2a","quotes":["Accordingly, CRC liver metastasis patients exhibited hyperactivation of hepa... | [
"CLM:45ea64a716f53fb2edb6df2a",
"CLM:71ac756b9724a4423f9240ec"
] | [
"PMCID:PMC8115036"
] | [
"SPAN:5e9621be1fd8700176c39d19"
] | [] | [] | {"qa_id":"QA:fce26d032c4b2ebded503673","qa_group_id":"QAG:f71a481b592d72a2262ec3a9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"Accordingly, CRC liver metastasis patients exhibited hyperactivati... |
QA:fe985af9b432841c8aaccc84 | QAG:98c6b4dc87c50b9f44b6086c | provenance_qa | exact_evidence_retrieval | provenance_qa | G013 | en | train | Which exact source passage supports the statement "3 , 4 Although therapeutic regimens for colon cancer, including surgery, chemotherapy, radiotherapy, and immunotherapy, have been greatly improved the 5-year survival rate only approximates 50%"? Return the original wording with paper, Claim, and Evidence Span referenc... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ea004ab274ed71d099b943b0","quotes":["3 , 4 Although therapeutic regimens for colon cancer, including surgery, che... | [
"CLM:ea004ab274ed71d099b943b0",
"CLM:0478df56bd5aa1173e674769"
] | [
"PMCID:PMC6598323"
] | [
"SPAN:a1d412baa82f5a0b8886cfa4"
] | [] | [] | {"qa_id":"QA:fe985af9b432841c8aaccc84","qa_group_id":"QAG:98c6b4dc87c50b9f44b6086c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G013","question":"Which exact source passage supports the statement \"3 , 4 Although therapeutic regimens for colon cancer, including su... |
QA:000f36ccb00a1e8c0704409a | QAG:1b9f0fb3122af186ec8d902e | provenance_qa | exact_evidence_retrieval | provenance_qa | G014 | en | train | Which exact source passage supports the statement "Multivariate analysis revealed that drug-resistant score (DRS) was a prognostic factor for overall survival (OS) in CRCpts in TCGA-CRC cohort ( P < 0.001)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:159fd4e91c8e904355d03d47","quotes":["Multivariate analysis revealed that drug-resistant score (DRS) was an indepe... | [
"CLM:159fd4e91c8e904355d03d47",
"CLM:0a58aec46a1065fe9c48847b"
] | [
"PMCID:PMC9004628"
] | [
"SPAN:1b09d6f21ae109d5bc9776b0"
] | [] | [] | {"qa_id":"QA:000f36ccb00a1e8c0704409a","qa_group_id":"QAG:1b9f0fb3122af186ec8d902e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Multivariate analysis revealed that drug-resistant score (DRS) was... |
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