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QA:0369010957355e67c767a944
QAG:9d9c7e6616bfd8c9ee3eb874
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "We discovered that drug responsiveness increased in the M-ORG medium in the oxaliplatin-sensitive CRC group ( Figure 5 A–C)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting p...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8cb2f0e289fce932d58a2d7c","quotes":["We discovered that drug responsiveness increased in the M-ORG medium in the ...
[ "CLM:8cb2f0e289fce932d58a2d7c", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:cce6f668b6ce3211a6c40bb2" ]
[]
[]
{"qa_id":"QA:0369010957355e67c767a944","qa_group_id":"QAG:9d9c7e6616bfd8c9ee3eb874","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"We discovered that drug responsiveness increased in the M-ORG medi...
QA:05acc3a2c623680e3b36910a
QAG:bfb2eaa8cb590072ae33d03c
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived organoids predicted chemoradiation responses of locally advanced rectal cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:36f0a2fc82a23eecf6424f55","quotes":["Patient-derived organoids predict chemoradiatio...
[ "CLM_SUP:36f0a2fc82a23eecf6424f55", "CLM:1cac52e2cbd154d19265a10b", "CLM:964599b1ed749bd860036142" ]
[ "PMCID:PMC10072204", "PMCID:PMC5127645" ]
[ "SPAN_SUP:f653115bb6cb7c3ee616e90c", "SPAN:7ea72f4e959671bb7008971e" ]
[ "ASC2:457b392264c1ee5fe8ba795f" ]
[ "HYP:DCH:631f65adbddef0d87bc9f851" ]
{"qa_id":"QA:05acc3a2c623680e3b36910a","qa_group_id":"QAG:bfb2eaa8cb590072ae33d03c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived organoids predicted chemoradiation responses of lo...
QA:06de69753ce53d55ed17577f
QAG:3c9eedf8da6b612d1b53f8e2
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "PDOs test predicted the response to biopsy lesions in more than 80% of patients treated with irinotecan in metastatic CRC patients, without misclassifying patients who would have benefited from this treatment"? Return the original wording with paper, Claim, and Evidenc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eae825b05f201e17d6ce537b","quotes":["PDOs test predicted the response to biopsy lesions in more than 80% of patie...
[ "CLM:eae825b05f201e17d6ce537b", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:a57b891b9b2d5b86cfc41318" ]
[]
[]
{"qa_id":"QA:06de69753ce53d55ed17577f","qa_group_id":"QAG:3c9eedf8da6b612d1b53f8e2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"PDOs test predicted the response to biopsy lesions in more than 80...
QA:0745a0cd175769e1810c62ea
QAG:b45319e462cc39d4a41b051a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Seeded cells were synchronized overnight by serum starvation to reduce the FBXW7 deficiency promoted cell division/growth in CRC cells, as reported previously, 23 , 24 , 30 , 32 , 35 prior to 72 hours incubation with 5-FU for cytotoxicity assay"? Return the original wo...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:85a497a886e069c071ddd7b2","quotes":["Seeded cells were synchronized overnight by serum starvation to reduce the F...
[ "CLM:85a497a886e069c071ddd7b2", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:93201cc503ec7771791773ac" ]
[]
[]
{"qa_id":"QA:0745a0cd175769e1810c62ea","qa_group_id":"QAG:b45319e462cc39d4a41b051a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Seeded cells were synchronized overnight by serum starvation to re...
QA:095a66638dfeee9077c6baaa
QAG:c87b8754770377bf7a565071
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9208081? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC9208081","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC9208081" ]
[]
[]
[]
{"qa_id":"QA:095a66638dfeee9077c6baaa","qa_group_id":"QAG:c87b8754770377bf7a565071","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9208081...
QA:09bde148b9d858a5334a2ed2
QAG:93700f3bed04af74dbf01179
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "5-Fluorouracil promoted apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-δ"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact sup...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:213dcff62e2f84aa96d1c1e5","quotes":["5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dep...
[ "CLM:213dcff62e2f84aa96d1c1e5", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:759eda6682dc89e7515d2ca7" ]
[]
[]
{"qa_id":"QA:09bde148b9d858a5334a2ed2","qa_group_id":"QAG:93700f3bed04af74dbf01179","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"5-Fluorouracil promoted apoptosis in colorectal cancer cells is ca...
QA:0b5bc4d10158d84101eb55ae
QAG:435e96a8441a9ae92bee2c13
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35273398? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:35273398","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:35273398" ]
[]
[]
[]
{"qa_id":"QA:0b5bc4d10158d84101eb55ae","qa_group_id":"QAG:435e96a8441a9ae92bee2c13","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35273398? E...
QA:0c38578831052ac953469370
QAG:7a0925a01b7c443983c06eb7
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Tumor tissue resections from colorectal cancer (CRC) patients were received from the USC Norris Comprehensive Cancer Center following institutional review board (IRB) approval and patient consent"? Return the original wording with paper, Claim, and Evidence Span refere...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c025d05547161c3dee3e91c9","quotes":["Tumor tissue resections from colorectal cancer (CRC) patients were received ...
[ "CLM:c025d05547161c3dee3e91c9", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC7372585" ]
[ "SPAN:7408344188f317756a113a1a" ]
[]
[]
{"qa_id":"QA:0c38578831052ac953469370","qa_group_id":"QAG:7a0925a01b7c443983c06eb7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Tumor tissue resections from colorectal cancer (CRC) patients were...
QA:0dafe9f1e42183ef9d02cdad
QAG:532a32ec282bc6fff19288d4
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8903172? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC8903172","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC8903172" ]
[]
[]
[]
{"qa_id":"QA:0dafe9f1e42183ef9d02cdad","qa_group_id":"QAG:532a32ec282bc6fff19288d4","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8903172...
QA:12dbfa8372a09f6dafcc5bad
QAG:037d58a083c96a5f1acf526b
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "PATIENTS: A total of 108 patients who underwent surgery with successful patient-derived tumor organoid culture and drug testing were enrolled between June 2018 and June 2019. INTERVENTIONS: Patient-derived tumor organoid culture and chemotherapeutic drug testing"? Retu...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:de80640f7bcbdd26270d1cbb","quotes":["PATIENTS: A total of 108 p...
[ "CLM:de80640f7bcbdd26270d1cbb", "CLM:0a58aec46a1065fe9c48847b", "CLM:e49826e9ab803ef3c982098b", "CLM:ee5340e77d50a52ad1902b72" ]
[ "PMCID:PMC10072204", "PMID:34633791", "PMCID:PMC9863259" ]
[ "SPAN:44b65ae26b7b6d719b839cce", "SPAN:7f5296582c2e59daed2d4772", "SPAN:6e27e2e60d22b7d4b15d64e0", "SPAN:dd4b077cd77906823659ea2d", "SPAN:e626c91e06fc2cbaeb2f2891" ]
[ "ASC2:d530f59f45c88db6c33230f3", "ASC2:8e6b6761cba63bc6a3878b30" ]
[ "HYP:DCH:b4a16b911d00e03d9ff282d8", "HYP:DCH:9a3403d9d44269d3ef8198f5" ]
{"qa_id":"QA:12dbfa8372a09f6dafcc5bad","qa_group_id":"QAG:037d58a083c96a5f1acf526b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"PATIENTS: A total of 108 patients who underwent surgery with succe...
QA:21b6b92df51e401c98db8a55
QAG:314dce1c6859e790c9e00227
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "There is an urgent need to develop new therapies for colorectal cancer that has metastasized to the liver and, more fundamentally, to develop improved preclinical platforms of colorectal cancer liver metastases (CRCLM) to screen therapies for efficacy"? Return the orig...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:646721b4e027fe64af27af32","quotes":["There is an urgent need to develop new therapies for colorectal cancer that ...
[ "CLM:646721b4e027fe64af27af32", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10264793" ]
[ "SPAN:069d94c498bed9eded6ac62c" ]
[]
[]
{"qa_id":"QA:21b6b92df51e401c98db8a55","qa_group_id":"QAG:314dce1c6859e790c9e00227","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"There is an urgent need to develop new therapies for colorectal ca...
QA:22b9c324f2107b94ee40e4e1
QAG:ab9b7b1f6e2c79b7345e9152
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "18 However, we find Berzosertib only increases SN-38 promoted apoptosis in microsatellite unstable (MSI) PDOs ( Fig- ure S5 I), suggesting ATR inhibitors might only be effective in MSI CRC patients"? Return the original wording with paper, Claim, and Evidence Span refer...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:02ff8ab5ecc9755da71f1be3","quotes":["18 However, we find Berzosertib only increases SN-38-\ninduced apoptosis in m...
[ "CLM:02ff8ab5ecc9755da71f1be3", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMID:38065081" ]
[ "SPAN:76e382b6021b1b7953bb1a83" ]
[]
[]
{"qa_id":"QA:22b9c324f2107b94ee40e4e1","qa_group_id":"QAG:ab9b7b1f6e2c79b7345e9152","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"18 However, we find Berzosertib only increases SN-38 promoted apopt...
QA:2584454a7d499920d989d38b
QAG:5a84158c5c32140589afdfb8
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "24 , 25 , 28 In vitro studies also reported that loss of FBXW7 function led to the acquisition of drug resistance in CRC cell lines, through the induction of an epithelial-mesenchymal transition (EMT) pathway, 32 and/or alteration of MCL1, 40 mTOR, 41 and TP53 status"?...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:947232baf5a32fd4cad7ed82","quotes":["24 , 25 , 28 In vitro studies also reported that loss of FBXW7 function lead...
[ "CLM:947232baf5a32fd4cad7ed82", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:4d6c6cd5eee8b08fa0ed5a7c" ]
[]
[]
{"qa_id":"QA:2584454a7d499920d989d38b","qa_group_id":"QAG:5a84158c5c32140589afdfb8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"24 , 25 , 28 In vitro studies also reported that loss of FBXW7 fun...
QA:265e3805696199cb0d34d7cc
QAG:aa6a3e9794811e565c6678cc
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Multivariate Cox analysis disclosed that 46 of 77 DRGs’ expression levels was correlated with the survival of CRCpts in TCGA-CRC dataset ( Table S6 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: ret...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:afc47b1b49c98ec924266338","quotes":["Multivariate Cox analysis disclosed that 46 of 77 DRGs’ expression levels we...
[ "CLM:afc47b1b49c98ec924266338", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC9004628" ]
[ "SPAN:d1da9415e4ec61af22288e42" ]
[]
[]
{"qa_id":"QA:265e3805696199cb0d34d7cc","qa_group_id":"QAG:aa6a3e9794811e565c6678cc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Multivariate Cox analysis disclosed that 46 of 77 DRGs’ expression...
QA:2ad11eee046b999338bd68ec
QAG:1bd54890285b725d67f5e11d
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Patients In the pilot study, 30 patients were enrolled and 43 samples were collected"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8ddb2cdd58cd0526b1593366","quotes":["Patients In the pilot study, 30 patients were enrolled, and 43 samples were ...
[ "CLM:8ddb2cdd58cd0526b1593366", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMID:33709991" ]
[ "SPAN:134bd96f56f85625cf85d44e", "SPAN:e538032100a41de720d4f2ce" ]
[]
[]
{"qa_id":"QA:2ad11eee046b999338bd68ec","qa_group_id":"QAG:1bd54890285b725d67f5e11d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Patients In the pilot study, 30 patients were enrolled and 43 samp...
QA:2e5a859d2dd034ca7d71e057
QAG:6957c98fd94c2dc0ad2926b2
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "We found high correlation between the observed and predicted drug responses in both colorectal cancer ( R 2 = 0.98) and bladder cancer organoids ( R 2 = 0.89) (Supplementary Fig. 17 ), which suggests that training the ML model with transcriptomes of proximal pathways h...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4beb76440091b02b5aad5613","quotes":["We found high correlation ...
[ "CLM:4beb76440091b02b5aad5613", "CLM:b06dd56d5e900ad96df07e77", "CLM:3534362f2a13bb5309c35d90", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMCID:PMC7599252", "PMCID:PMC4830362", "PMID:30261425" ]
[ "SPAN:eab69bbe992bbe1a67438848", "SPAN:d2cce74a0e291981c9e35923", "SPAN:440f50b100e1b5459f0aaf55" ]
[ "ASC2:fa4fe5760b4b63c1ec23fcc4", "ASC2:533e917b1db0c459cfb25646" ]
[ "HYP:DCH:6d8eaa3fc39a01eb0797102b", "HYP:DCH:7f92fd1f21c745843c40155b" ]
{"qa_id":"QA:2e5a859d2dd034ca7d71e057","qa_group_id":"QAG:6957c98fd94c2dc0ad2926b2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"We found high correlation between the observed and predicted drug ...
QA:2ea14de0859aef90283cd22b
QAG:cf8cc48fa1a405a7c053aced
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "In our previous study, 21 we generated PDTOs from 30 samples from patients with stage IV CRC who received chemotherapy, which enabled us to correlate drug sensitivity in PDTOs with chemosensitivity in the clinic"? Return the original wording with paper, Claim, and Evid...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7d62ba8a0eeeb70812a293fb","quotes":["In our previous study, 21 we generated PDTOs from 30 samples from patients w...
[ "CLM:7d62ba8a0eeeb70812a293fb", "CLM:b06dd56d5e900ad96df07e77" ]
[ "PMCID:PMC10072204" ]
[ "SPAN:3dc248808910a1656ab63c29" ]
[]
[]
{"qa_id":"QA:2ea14de0859aef90283cd22b","qa_group_id":"QAG:cf8cc48fa1a405a7c053aced","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"In our previous study, 21 we generated PDTOs from 30 samples from ...
QA:3048b785e9de00019e6c7f54
QAG:25c0df4c0c78728f65cc326e
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "It was observed that NIH3T3 cells promoted the kinetics of tumor organoid formation"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence S...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e49826e9ab803ef3c982098b","quotes":["It was observed that NIH3T...
[ "CLM:e49826e9ab803ef3c982098b", "CLM:0a58aec46a1065fe9c48847b", "CLM:6c993178b3e2e0383c815678", "CLM:de80640f7bcbdd26270d1cbb" ]
[ "PMID:34633791", "PMCID:PMC5127645", "PMCID:PMC10072204" ]
[ "SPAN:6e27e2e60d22b7d4b15d64e0", "SPAN:dd4b077cd77906823659ea2d", "SPAN:6e6fdbb34e5935f19e5a7a36", "SPAN:44b65ae26b7b6d719b839cce", "SPAN:7f5296582c2e59daed2d4772" ]
[ "ASC2:8664c74d9394f35741bb9174", "ASC2:d530f59f45c88db6c33230f3" ]
[ "HYP:DCH:0154642ca6a3c97bc53f6f90", "HYP:DCH:b40e5e28432694d8e3c78c92" ]
{"qa_id":"QA:3048b785e9de00019e6c7f54","qa_group_id":"QAG:25c0df4c0c78728f65cc326e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"It was observed that NIH3T3 cells promoted the kinetics of tumor o...
QA:344e5ca3c1aa3ca7c0c0c1e9
QAG:2815ff911ba2218b0b06d486
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "30 , 32 , 40 , 44 , 45 However, beyond the scope of this current study and the importance of given data here and our published and unpublished data on links between EMT and FBXW7, more recently, we have initiated a study using different approaches to explore molecular ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3534362f2a13bb5309c35d90","quotes":["30 , 32 , 40 , 44 , 45 However, beyond the scope of...
[ "CLM:3534362f2a13bb5309c35d90", "CLM:910db38e3f606d63a75a2412", "CLM:3a5d83a22549a75ae2253455", "CLM:6c993178b3e2e0383c815678", "CLM:ee5340e77d50a52ad1902b72" ]
[ "PMCID:PMC4830362", "PMCID:PMC9863259", "PMCID:PMC5127645" ]
[ "SPAN:d2cce74a0e291981c9e35923", "SPAN:1b3bc93518394d8a1ac7643d", "SPAN:6e6fdbb34e5935f19e5a7a36", "SPAN:e626c91e06fc2cbaeb2f2891" ]
[ "ASC2:5b92f820953cbd9124b9d32d", "ASC2:77cd8c6d6b9f76d4336bd75e" ]
[ "HYP:DCH:7fad72200d80b85d8b600415" ]
{"qa_id":"QA:344e5ca3c1aa3ca7c0c0c1e9","qa_group_id":"QAG:2815ff911ba2218b0b06d486","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"30 , 32 , 40 , 44 , 45 However, beyond the scope of this current s...
QA:35a94cee2ae5e8d8351c765b
QAG:e684808aa11a7c4977fdcfff
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35691158? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:35691158","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:35691158" ]
[]
[]
[]
{"qa_id":"QA:35a94cee2ae5e8d8351c765b","qa_group_id":"QAG:e684808aa11a7c4977fdcfff","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35691158? E...
QA:3c6cf8368a072f4bba996912
QAG:f030e255129e239268d35c1f
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:37774672? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:37774672","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:37774672" ]
[]
[]
[]
{"qa_id":"QA:3c6cf8368a072f4bba996912","qa_group_id":"QAG:f030e255129e239268d35c1f","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:37774672? E...
QA:41967eec988db0888fa80ab4
QAG:1fc31cda1ea76dad8616e036
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC12978046? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiabl...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC12978046","verdict":"no_released_traceable_claim","reason":"No...
[]
[ "PMCID:PMC12978046" ]
[]
[]
[]
{"qa_id":"QA:41967eec988db0888fa80ab4","qa_group_id":"QAG:1fc31cda1ea76dad8616e036","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC1297804...
QA:4860bd6923d7f9583be88271
QAG:aef2a90c7ba5240b23c99e4d
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Moreover, treatment of primary patient-derived colon cancer organoids was similarly efficient and led to increased apoptosis and decreased proliferation in both combined PKI/AZD as well as T/MK/AZD treatment"? Return the original wording with paper, Claim, and Evidence...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ee5340e77d50a52ad1902b72","quotes":["Moreover, treatment of primary patient-derived colo...
[ "CLM:ee5340e77d50a52ad1902b72", "CLM:0a58aec46a1065fe9c48847b", "CLM:de80640f7bcbdd26270d1cbb", "CLM_SUP:5a32018fa8cbc303bb9e406e", "CLM_SUP:64fb7fd0f50505498fc5b44d" ]
[ "PMCID:PMC9863259", "PMCID:PMC10072204", "PMID:33709991" ]
[ "SPAN:e626c91e06fc2cbaeb2f2891", "SPAN:44b65ae26b7b6d719b839cce", "SPAN:7f5296582c2e59daed2d4772", "SPAN_SUP:1792e8103bdf8986c0dc1d29", "SPAN_SUP:97e8a8b85531c891e352f25c" ]
[ "ASC2:8e6b6761cba63bc6a3878b30", "ASC2:365b2ea63f197dec49e05752" ]
[ "HYP:DCH:92a778ab39ce1e63ed6a2b80" ]
{"qa_id":"QA:4860bd6923d7f9583be88271","qa_group_id":"QAG:aef2a90c7ba5240b23c99e4d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Moreover, treatment of primary patient-derived colon cancer organo...
QA:4a0a545ce79f9178d979f168
QAG:8bd8293c937f6ef7db30e47e
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "For example, in a patient with right-sided colon cancer who underwent R0 resection and had adenocarcinoma, the probability of 12-month PFS for a patient with resistance indicated by the PDTO-based drug test was approximately 20%, and for patients with sensitivity indic...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8ddb7b65e496910d0ca6321d","quotes":["For example, in a patient with right-sided colon cancer who underwent R0 res...
[ "CLM:8ddb7b65e496910d0ca6321d", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10072204" ]
[ "SPAN:9f5fd5bc865b65f864be6549" ]
[]
[]
{"qa_id":"QA:4a0a545ce79f9178d979f168","qa_group_id":"QAG:8bd8293c937f6ef7db30e47e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"For example, in a patient with right-sided colon cancer who underw...
QA:4bb9edeb4756fb89967f0975
QAG:8a0785eb913f8128ef4baa4b
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6317967? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC6317967","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC6317967" ]
[]
[]
[]
{"qa_id":"QA:4bb9edeb4756fb89967f0975","qa_group_id":"QAG:8a0785eb913f8128ef4baa4b","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6317967...
QA:4c7347c5c20b9fb0f04278d6
QAG:0d2b9de75f939049db193b07
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived crc organoids p18t-kras received different combination therapies against the egfr-ras-erk pathway with addition of bcl2/bclxl inhibitor navitoclax and th"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenan...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:014740537b08b223a172c6b3","quotes":["Dose-response curves of patient-derived CRC org...
[ "CLM_SUP:014740537b08b223a172c6b3", "CLM:0a58aec46a1065fe9c48847b", "CLM:ef45b3c1494f9cf78e2f842a" ]
[ "PMCID:PMC5127645", "PMCID:PMC10705195" ]
[ "SPAN_SUP:e4e7feba61a8411657f2cd24", "SPAN:5d622113352f3a93339b7092" ]
[ "ASC2:c8f262f197b93d196501fb7d" ]
[ "HYP:DCH:28a080c5f4c88fa5f216d498" ]
{"qa_id":"QA:4c7347c5c20b9fb0f04278d6","qa_group_id":"QAG:0d2b9de75f939049db193b07","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived crc organoids p18t-kras received different combina...
QA:520d08d9baa965d34ad62493
QAG:4f5437d6b77e18fabaa69fa1
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "EXPERIMENTAL MODEL AND SUBJECT DETAILS CRC PDO and CRC CAF culture CRC PDOs were obtained from the Human Cancer Models Initiative (Sanger Institute, Cambridge, UK) 12 and expanded in 12-well plates (Helena Biosciences 92412T) in x3 25 mL droplets of Growth Factor decre...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d633a27f9272af337b82f7d8","quotes":["EXPERIMENTAL MODEL AND SUBJECT DETAILS\nCRC PDO and CRC CAF culture\nCRC PDO...
[ "CLM:d633a27f9272af337b82f7d8", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMID:38065081" ]
[ "SPAN:f0a63c28b51d2cf32a9d095e" ]
[]
[]
{"qa_id":"QA:520d08d9baa965d34ad62493","qa_group_id":"QAG:4f5437d6b77e18fabaa69fa1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"EXPERIMENTAL MODEL AND SUBJECT DETAILS CRC PDO and CRC CAF culture...
QA:5222d9986adeddc4812ea61c
QAG:7f1b833577ba7a02edfc04c8
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC10530407? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiabl...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC10530407","verdict":"no_released_traceable_claim","reason":"No...
[]
[ "PMCID:PMC10530407" ]
[]
[]
[]
{"qa_id":"QA:5222d9986adeddc4812ea61c","qa_group_id":"QAG:7f1b833577ba7a02edfc04c8","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC1053040...
QA:5273406f64f882933fa1a2e3
QAG:641a9e2b9e453780c854f38a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived kras mutant crc organoids p9t and p26t received the dual egfr/her2 inhibitor afatinib"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Cla...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:9b2fe8504bc44cbeb841ae5e","quotes":["Dose-response curves of patient-derived KRAS mutant CRC organoids P9T an...
[ "CLM_SUP:9b2fe8504bc44cbeb841ae5e", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC5127645" ]
[ "SPAN_SUP:fd7ec420dac6fc34f637c320" ]
[]
[]
{"qa_id":"QA:5273406f64f882933fa1a2e3","qa_group_id":"QAG:641a9e2b9e453780c854f38a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived kras mutant crc organoids p9t and p26t received th...
QA:532ec8ccb85e3eaa5d700c55
QAG:52fbf23f6c7d42ac3b96bc6e
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Intra-tumor heterogeneity (genotypic and functional diversity among cancer cells within the same tumor) represented one of the key challenges in cancer medicine"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requir...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d5cf7f03a5e8504f09acbe5f","quotes":["Intra-tumor heterogeneity (genotypic and functional diversity among cancer c...
[ "CLM:d5cf7f03a5e8504f09acbe5f", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMID:30261425" ]
[ "SPAN:58303611749f623592498f55" ]
[]
[]
{"qa_id":"QA:532ec8ccb85e3eaa5d700c55","qa_group_id":"QAG:52fbf23f6c7d42ac3b96bc6e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Intra-tumor heterogeneity (genotypic and functional diversity amon...
QA:5343b7091454f246ae8c70d5
QAG:abad87d827a25bac6284f94a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived tumor organoids predicted progression-free survival in patients with stage iv colorectal cancer after surgery"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:5a32018fa8cbc303bb9e406e","quotes":["CONCLUSIONS: Patient-derived tumor organoids ca...
[ "CLM_SUP:5a32018fa8cbc303bb9e406e", "CLM:02ff8ab5ecc9755da71f1be3", "CLM_SUP:64fb7fd0f50505498fc5b44d" ]
[ "PMCID:PMC10072204", "PMID:33709991" ]
[ "SPAN_SUP:1792e8103bdf8986c0dc1d29", "SPAN_SUP:97e8a8b85531c891e352f25c" ]
[ "ASC2:365b2ea63f197dec49e05752" ]
[ "HYP:DCH:e5cb8551cae0dec5757312b7" ]
{"qa_id":"QA:5343b7091454f246ae8c70d5","qa_group_id":"QAG:abad87d827a25bac6284f94a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived tumor organoids predicted progression-free surviva...
QA:54eb38fa88f8f669732c93bc
QAG:37c6a1cd884e535d9e7d5449
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Rapamycin inhibits FBXW7 loss promoted epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b54d1f125363612ac32a3275","quotes":["Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and ...
[ "CLM:b54d1f125363612ac32a3275", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:dffb17a14ef65f0520795174" ]
[]
[]
{"qa_id":"QA:54eb38fa88f8f669732c93bc","qa_group_id":"QAG:37c6a1cd884e535d9e7d5449","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Rapamycin inhibits FBXW7 loss promoted epithelial-mesenchymal tran...
QA:55c33ec472bd361be08f9f91
QAG:b7a03fc83b08d4e56dfef990
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "The survival rate of patients with advanced CRC has been substantially improved due to the use of chemotherapeutics, the introduction of targeted therapies for specific tumor characteristics, and the combination of multidisciplinary methods"? Return the original wordin...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:715d70635718feefb56717f2","quotes":["The survival rate of patients with advanced CRC has been substantially impro...
[ "CLM:715d70635718feefb56717f2", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:be3e8559d6507bce9e67814b" ]
[]
[]
{"qa_id":"QA:55c33ec472bd361be08f9f91","qa_group_id":"QAG:b7a03fc83b08d4e56dfef990","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"The survival rate of patients with advanced CRC has been substanti...
QA:568e426b24b0cc8abadd4f15
QAG:1afb6aa2bc1783c633b28113
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Cu overload was associated with the progression and prognosis of colorectal cancer (CRC) 9"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:33c98ff8e87694040b6bb8ee","quotes":["Cu overload is associated with the progression and prognosis of colorectal c...
[ "CLM:33c98ff8e87694040b6bb8ee", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10367564" ]
[ "SPAN:9f3b3924ec8b0ef523e6a5b2" ]
[]
[]
{"qa_id":"QA:568e426b24b0cc8abadd4f15","qa_group_id":"QAG:1afb6aa2bc1783c633b28113","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Cu overload was associated with the progression and prognosis of c...
QA:5c586fa7ef525f05f4f3d45c
QAG:ee9c7ac46b1001aac3881e6f
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "According to the literature, the Wnt/β-catenin signaling pathway was associated with chemoresistance in CRC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with pape...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1f76719e9372c7dee5e47742","quotes":["According to the literature, the Wnt/β-catenin signaling pathway is associat...
[ "CLM:1f76719e9372c7dee5e47742", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:b1ca56e5379a1c538863f693" ]
[]
[]
{"qa_id":"QA:5c586fa7ef525f05f4f3d45c","qa_group_id":"QAG:ee9c7ac46b1001aac3881e6f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"According to the literature, the Wnt/β-catenin signaling pathway w...
QA:5d83fbcaf9347bf7e3eebb11
QAG:bb757745eedc8e6503a3af37
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "RC tumoroids retained molecular features of the tumors from which they were derived, and their ex vivo responses to clinically relevant chemotherapy and radiation treatment correlated with the clinical responses noted in individual patients' tumors"? Return the origina...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:79dbd1795c2e01ceceba8990","quotes":["RC tumoroids retained molecular features of the tumors from which they were ...
[ "CLM:79dbd1795c2e01ceceba8990", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMCID:PMC7385919" ]
[ "SPAN:09b219148c84c303e06fe413" ]
[]
[]
{"qa_id":"QA:5d83fbcaf9347bf7e3eebb11","qa_group_id":"QAG:bb757745eedc8e6503a3af37","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"RC tumoroids retained molecular features of the tumors from which ...
QA:5deedaf9ca13e8a178021c2f
QAG:32cdfa94733ea17f41fbd332
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Previous studies have reported that the Wnt/β-catenin signaling pathway was associated with chemoresistance in CRC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage wi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fedbd665376dc8cccd3280a9","quotes":["Previous studies have reported that the Wnt/β-catenin signaling pathway is a...
[ "CLM:fedbd665376dc8cccd3280a9", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:dd23342d025e8242453efc1a" ]
[]
[]
{"qa_id":"QA:5deedaf9ca13e8a178021c2f","qa_group_id":"QAG:32cdfa94733ea17f41fbd332","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Previous studies have reported that the Wnt/β-catenin signaling pa...
QA:5e9adf79def63a544aedc4d3
QAG:d88a171915f9836638293711
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "With further research, our present findings can contribute to increased favorable prognoses and OS for CRC patients by providing personalized chemotherapy through high-precision prediction models"? Return the original wording with paper, Claim, and Evidence Span refere...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a5cbd4d51a7d189b1928726","quotes":["With further research, our present findings can contribute to increased favo...
[ "CLM:9a5cbd4d51a7d189b1928726", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:f54980788bbae40304e871c6" ]
[]
[]
{"qa_id":"QA:5e9adf79def63a544aedc4d3","qa_group_id":"QAG:d88a171915f9836638293711","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"With further research, our present findings can contribute to incr...
QA:616a25304b1a1e279f2bdfd5
QAG:80966d0391ec38de5b2fd8db
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35907519? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:35907519","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:35907519" ]
[]
[]
[]
{"qa_id":"QA:616a25304b1a1e279f2bdfd5","qa_group_id":"QAG:80966d0391ec38de5b2fd8db","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35907519? E...
QA:62d272ba48a8796c22cbf846
QAG:1d47be39d4a6bbb7b3d5c73a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived crc organoids p18t-kras g12d received the dual egfr/her2 inhibitor afatinib"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Ev...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:ce2b739677580355536bf0b5","quotes":["( A ) Dose-response curves of patient-derived CRC organoids P18T-KRAS G1...
[ "CLM_SUP:ce2b739677580355536bf0b5", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC5127645" ]
[ "SPAN_SUP:2c311b8b7fa0f344b8b153b7" ]
[]
[]
{"qa_id":"QA:62d272ba48a8796c22cbf846","qa_group_id":"QAG:1d47be39d4a6bbb7b3d5c73a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived crc organoids p18t-kras g12d received the dual egf...
QA:6c7f5bfae9802c1d1c9b21b8
QAG:f4642130f141f0a334eca129
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "It was worth noting that only stage II–IV CRCpts were enrolled in the current study because patients with stage I disease underwent surgical resection but did not receive 5-Fu chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references. ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e47544b765c3cdd2d7e69c68","quotes":["It was worth noting that only stage II–IV CRCpts were enrolled in the curren...
[ "CLM:e47544b765c3cdd2d7e69c68", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC9004628" ]
[ "SPAN:6b187f19372a9267466c1543", "SPAN:a9e5dc154fc4228ee41ef1b1" ]
[]
[]
{"qa_id":"QA:6c7f5bfae9802c1d1c9b21b8","qa_group_id":"QAG:f4642130f141f0a334eca129","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"It was worth noting that only stage II–IV CRCpts were enrolled in ...
QA:7af58104e6a78f3aa6c103da
QAG:dc9a6981c5818027359e8f57
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Cetuximab increased the Cytotoxic Activity of Immune Cells during Treatment of Colorectal Cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, a...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3271ad4dde69864aa497bbfe","quotes":["30. Wang L, Wei Y, Fang W, Lu C, Chen J, Cui G, et al. Cetuximab Enhanced th...
[ "CLM:3271ad4dde69864aa497bbfe", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC6457557" ]
[ "SPAN:88c16047ca3907d9600d10e7" ]
[]
[]
{"qa_id":"QA:7af58104e6a78f3aa6c103da","qa_group_id":"QAG:dc9a6981c5818027359e8f57","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Cetuximab increased the Cytotoxic Activity of Immune Cells during ...
QA:7ba1f01b9984ea18064a9fd6
QAG:7f54ae012f1b31b6f6fd2af2
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "If this research progresses, it can ultimately contribute to increased favorable prognoses and OS for colorectal cancer patients by providing personalized chemotherapy through high-precision prediction models"? Return the original wording with paper, Claim, and Evidenc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d085cc1f78d80c5f4ee33ed3","quotes":["If this research progresses, it can ultimately contribute to increased favor...
[ "CLM:d085cc1f78d80c5f4ee33ed3", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:8c64c6fbe95662045aed7e97" ]
[]
[]
{"qa_id":"QA:7ba1f01b9984ea18064a9fd6","qa_group_id":"QAG:7f54ae012f1b31b6f6fd2af2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"If this research progresses, it can ultimately contribute to incre...
QA:7c2ed1cdfede7f92a995bae4
QAG:a2b87d0733961fb990fe13e3
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6774804? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC6774804","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC6774804" ]
[]
[]
[]
{"qa_id":"QA:7c2ed1cdfede7f92a995bae4","qa_group_id":"QAG:a2b87d0733961fb990fe13e3","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6774804...
QA:7f60124f9f33bfcb22808011
QAG:527945cc1bc53f6d255d825a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "However, this is not the case for all CRC patients, since a subset of tumors do not respond as predicted presumably because of the presence of additional genetic alterations confounding genetic interactions"? Return the original wording with paper, Claim, and Evidence ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0f5b405cc756bd984e1a5182","quotes":["However, this is not the case for all CRC patients, since a subset of tumors...
[ "CLM:0f5b405cc756bd984e1a5182", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC4335404" ]
[ "SPAN:7b4a1764760fc3591e085f81" ]
[]
[]
{"qa_id":"QA:7f60124f9f33bfcb22808011","qa_group_id":"QAG:527945cc1bc53f6d255d825a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"However, this is not the case for all CRC patients, since a subset...
QA:8467e4ffcd9b471a21917b9e
QAG:1acdbcdf5a9b96b243731b45
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "As heterogeneity of cancer cells constitutes an important parameter in the development of therapy resistance, an accurate assessment of intra-tumor heterogeneity was essential for the prediction of drug resistance and development of effective treatment"? Return the ori...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e824127c3842ffd02a279fc9","quotes":["As heterogeneity of cancer cells constitutes an important parameter in the d...
[ "CLM:e824127c3842ffd02a279fc9", "CLM:059e67f3b234cf4911e5e52b" ]
[ "PMID:30261425" ]
[ "SPAN:405a02f2ab4051c46f9a3e7c" ]
[]
[]
{"qa_id":"QA:8467e4ffcd9b471a21917b9e","qa_group_id":"QAG:1acdbcdf5a9b96b243731b45","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"As heterogeneity of cancer cells constitutes an important paramete...
QA:86fbd3d6a14e4a3a030a2133
QAG:a9f5bad78f92008701f35243
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "A Wnt promoted Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits Emt in Colorectal Cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8ef051b60489ae5de7863b3b","quotes":["A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits Em...
[ "CLM:8ef051b60489ae5de7863b3b", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:dd5cfe429f811d9133a3cd23" ]
[]
[]
{"qa_id":"QA:86fbd3d6a14e4a3a030a2133","qa_group_id":"QAG:a9f5bad78f92008701f35243","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"A Wnt promoted Phenotypic Switch in Cancer-Associated Fibroblasts ...
QA:87a7eafd6a6e1d9e2a740e77
QAG:bc545f360848c10ae511893e
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "A total of 1,281 CRC patients from three Gene Expression Omnibus (GEO) databases were enrolled (accession # GSE39582 , # GSE196576 , and # GSE28702 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: ret...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ac046406177eba3bbad70d5b","quotes":["A total of 1,281 CRC patients from three Gene Expression Omnibus (GEO) datab...
[ "CLM:ac046406177eba3bbad70d5b", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10367564" ]
[ "SPAN:866fd49b926e193d8435da1f" ]
[]
[]
{"qa_id":"QA:87a7eafd6a6e1d9e2a740e77","qa_group_id":"QAG:bc545f360848c10ae511893e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"A total of 1,281 CRC patients from three Gene Expression Omnibus (...
QA:897f969a9d00771ffbaf8fd2
QAG:36036315dba904435e452c77
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "RC tumoroids retained molecular features of the tumors from which they were derived, and their ex vivo responses to clinically relevant chemotherapy and radiation treatment was correlated with the clinical responses noted in individual patients' tumors"? Return the ori...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0a58aec46a1065fe9c48847b","quotes":["RC tumoroids retained molecular features of the tumors from which they were ...
[ "CLM:0a58aec46a1065fe9c48847b", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMCID:PMC7385919" ]
[ "SPAN:09b219148c84c303e06fe413" ]
[]
[]
{"qa_id":"QA:897f969a9d00771ffbaf8fd2","qa_group_id":"QAG:36036315dba904435e452c77","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"RC tumoroids retained molecular features of the tumors from which ...
QA:90edb976644102c529e3d656
QAG:b01f4c40cbbbce165a8199c3
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6527507? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC6527507","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC6527507" ]
[]
[]
[]
{"qa_id":"QA:90edb976644102c529e3d656","qa_group_id":"QAG:b01f4c40cbbbce165a8199c3","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6527507...
QA:99688b5464c1f5ffb12dce35
QAG:e687cf0f274ea148c18643ab
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "the IC 50 of fbxw7 mutant mini-guts was higher than controls (5.7 versus 2.6 μmol/l 5-FU, respectively) ( Figure 3c )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f3224ce5a2b67f109091305f","quotes":["Consistent with CRC cell lines, we further confirmed that Fbxw7 deficiency c...
[ "CLM:f3224ce5a2b67f109091305f", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:414f5899289b31aa0fae40ca" ]
[]
[]
{"qa_id":"QA:99688b5464c1f5ffb12dce35","qa_group_id":"QAG:e687cf0f274ea148c18643ab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"the IC 50 of fbxw7 mutant mini-guts was higher than controls (5.7 ...
QA:a46962989002cc58704463d3
QAG:1136ec8a8d73c3ae09c2a89b
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "( A ) Schematic representation of the CRISPR/Cas9 promoted homologous recombination strategy to introduce the KRAS G12D mutation in the KRAS WT patient-derived CRC organoid P18T"? Return the original wording with paper, Claim, and Evidence Span references. Integrated ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:964599b1ed749bd860036142","quotes":["10.7554/eLife.18489.010 Figure 3. CRISPR genome edi...
[ "CLM:964599b1ed749bd860036142", "CLM:0a58aec46a1065fe9c48847b", "CLM_SUP:64fb7fd0f50505498fc5b44d" ]
[ "PMCID:PMC5127645", "PMID:33709991" ]
[ "SPAN:7ea72f4e959671bb7008971e", "SPAN_SUP:97e8a8b85531c891e352f25c" ]
[ "ASC2:7806e5e8f505dd152e7a2530" ]
[ "HYP:DCH:3a602efb2c5e2f3031c9f390" ]
{"qa_id":"QA:a46962989002cc58704463d3","qa_group_id":"QAG:1136ec8a8d73c3ae09c2a89b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"( A ) Schematic representation of the CRISPR/Cas9 promoted homolog...
QA:a509e094529fcf882e49bdbb
QAG:8b5a9266eb5f867854889424
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Analysis of 172 CRC surgical specimens revealed that high STAG3 expression was associated with poor prognosis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:112d6871a86efb0739067458","quotes":["Analysis of 172 CRC surgical specimens revealed that high STAG3 expression w...
[ "CLM:112d6871a86efb0739067458", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMID:33039558" ]
[ "SPAN:f8130b44cc110dda36368d41" ]
[]
[]
{"qa_id":"QA:a509e094529fcf882e49bdbb","qa_group_id":"QAG:8b5a9266eb5f867854889424","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Analysis of 172 CRC surgical specimens revealed that high STAG3 ex...
QA:a5d79d3440d2df186b8ca6d1
QAG:d86e47653eb00b14f2c0f927
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "As a negative control, we compared the differences in overall survival of 298 colorectal cancer patients with no prior treatment who were predicted to be sensitive or resistant to 5FU treatment (Fig. 2d )"? Return the original wording with paper, Claim, and Evidence Sp...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9b2ae1447430367097d89814","quotes":["As a negative control, we compared the differences in overall survival of 29...
[ "CLM:9b2ae1447430367097d89814", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC7599252" ]
[ "SPAN:40ae117c894dced7a81d8602" ]
[]
[]
{"qa_id":"QA:a5d79d3440d2df186b8ca6d1","qa_group_id":"QAG:d86e47653eb00b14f2c0f927","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"As a negative control, we compared the differences in overall surv...
QA:a5e71e2ab2669bebba1d3783
QAG:3686cd22257ba3343e02b6a5
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "We found that the expression levels of the components of the “activation of BH3-only proteins” pathway was associated with the responses of colorectal cancer organoids to 5FU treatment"? Return the original wording with paper, Claim, and Evidence Span references. Inte...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9784298cad461ea96f6cabec","quotes":["We found that the expression levels of the components of the “activation of ...
[ "CLM:9784298cad461ea96f6cabec", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC7599252" ]
[ "SPAN:3fb3f56265f4eec55b0cfeb5" ]
[]
[]
{"qa_id":"QA:a5e71e2ab2669bebba1d3783","qa_group_id":"QAG:3686cd22257ba3343e02b6a5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"We found that the expression levels of the components of the “acti...
QA:a6228dbc3fd993bac9d62d82
QAG:0faa7e53af8e7914aeb4df5a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Finally, we address the exciting recent results that showed that tumor organoid technology is highly predictive for drug response in metastatic colorectal cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d6cf25e9df24e15ceeac556a","quotes":["Finally, we address the ex...
[ "CLM:d6cf25e9df24e15ceeac556a", "CLM:0a58aec46a1065fe9c48847b", "CLM:6627364fd1e47da0d8f06e70", "CLM:a6b95e4bd8a8acf73bc9ba67", "CLM:4beb76440091b02b5aad5613", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMID:30261425", "PMCID:PMC5127645", "PMCID:PMC6457557", "PMCID:PMC7599252" ]
[ "SPAN:d4a3832497d3396828b39d40", "SPAN:69d5b0c787468fc7945efef2", "SPAN:f6dcfd8170d15a611d255fef", "SPAN:440f50b100e1b5459f0aaf55", "SPAN:eab69bbe992bbe1a67438848" ]
[ "ASC2:53a1cc586b5a13cacde98b8c", "ASC2:e87b1d6b884d3b661af2a2ed", "ASC2:533e917b1db0c459cfb25646", "ASC2:ec5f54b918dee48afaff30cf" ]
[ "HYP:DCH:3d1ae445f1b242a5bc980add", "HYP:DCH:cee4bf86bdb6e94338ed68d3" ]
{"qa_id":"QA:a6228dbc3fd993bac9d62d82","qa_group_id":"QAG:0faa7e53af8e7914aeb4df5a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Finally, we address the exciting recent results that showed that t...
QA:a65af2a7d911907898b012f4
QAG:f84418ff55161fcb96ad6c40
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "21 different rectal cancer (RC) organoids were separately treated with 5-FU and FOLFOX (a chemotherapy regimen of 5-FU, leucovorin, and oxaliplatin), and 19 RC organoids were received radiation treatment"? Return the original wording with paper, Claim, and Evidence Spa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f54069ba209b0b546772576d","quotes":["21 different rectal cancer (RC) organoids were separately treated with 5-FU ...
[ "CLM:f54069ba209b0b546772576d", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:d373e0eccc6d6a6a606a3406" ]
[]
[]
{"qa_id":"QA:a65af2a7d911907898b012f4","qa_group_id":"QAG:f84418ff55161fcb96ad6c40","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"21 different rectal cancer (RC) organoids were separately treated ...
QA:a6d187c975fd967cfc89cc84
QAG:7331f8e57c0d20a19d683f64
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Figure 8 CRC PDO drug sensitivity predicted response to treatment with oxaliplatin in the M-ORG media condition. ( A ) CRC-166T organoids were administered increasing doses of oxaliplatin (0.024~100 μM) for 5 days in three different culture media (TCCM/ORG/M-ORG)"? Ret...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ef45b3c1494f9cf78e2f842a","quotes":["Figure 8 CRC PDO drug sensitivity predicts response...
[ "CLM:ef45b3c1494f9cf78e2f842a", "CLM:0a58aec46a1065fe9c48847b", "CLM_SUP:36f0a2fc82a23eecf6424f55" ]
[ "PMCID:PMC10705195", "PMCID:PMC10072204" ]
[ "SPAN:5d622113352f3a93339b7092", "SPAN_SUP:f653115bb6cb7c3ee616e90c" ]
[ "ASC2:25fba721279a7de7d79ffab8" ]
[ "HYP:DCH:5cfe45e5ade56bb69673da29" ]
{"qa_id":"QA:a6d187c975fd967cfc89cc84","qa_group_id":"QAG:7331f8e57c0d20a19d683f64","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Figure 8 CRC PDO drug sensitivity predicted response to treatment ...
QA:a806e8f7ab2f27a659f3cc7e
QAG:d9594522a4f7141d983ca89f
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Particularly, in BRAF-mutant CRC cells, STAG3 silencing inhibited the expression of snail family transcriptional repressor 1 and phosphorylation of extracellular signal-regulated kinase via upregulation of dual-specificity phosphatase 6. Our findings suggest that STAG3...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a260dc82c1bc0c36ca58fa1","quotes":["Particularly, in BRAF-mutant CRC cells, STAG3 silencing suppressed the expre...
[ "CLM:9a260dc82c1bc0c36ca58fa1", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMID:33039558" ]
[ "SPAN:8a437dd5e910ba5f03b9da0d" ]
[]
[]
{"qa_id":"QA:a806e8f7ab2f27a659f3cc7e","qa_group_id":"QAG:d9594522a4f7141d983ca89f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Particularly, in BRAF-mutant CRC cells, STAG3 silencing inhibited ...
QA:aa63e029839db28574b2eff4
QAG:227ef966076c901b35dd9222
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "the predictive accuracy of patient-derived tumor organoid culture models for responses to chemotherapy regimens in stage iv colorectal cancer remains unknown"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requireme...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:64fb7fd0f50505498fc5b44d","quotes":["However, the predictive accuracy of patient-derived tumor organoid cultu...
[ "CLM_SUP:64fb7fd0f50505498fc5b44d", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMID:33709991" ]
[ "SPAN_SUP:97e8a8b85531c891e352f25c" ]
[]
[]
{"qa_id":"QA:aa63e029839db28574b2eff4","qa_group_id":"QAG:227ef966076c901b35dd9222","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"the predictive accuracy of patient-derived tumor organoid culture ...
QA:bb0cb7cadc4d598c11588a75
QAG:7d4f5ff551992b3323ab05df
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Recently, several groups have described patient-derived colorectal cancer organoids as a discovery platform for therapeutics and for validating the predicted impact of molecular features on therapy responses"? Return the original wording with paper, Claim, and Evidence...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a6b95e4bd8a8acf73bc9ba67","quotes":["Recently, several groups have described patient-der...
[ "CLM:a6b95e4bd8a8acf73bc9ba67", "CLM:5ef8a344ca03ab96e5854565", "CLM:d6cf25e9df24e15ceeac556a" ]
[ "PMCID:PMC6457557", "PMID:30261425" ]
[ "SPAN:f6dcfd8170d15a611d255fef", "SPAN:d4a3832497d3396828b39d40" ]
[ "ASC2:ec5f54b918dee48afaff30cf" ]
[ "HYP:DCH:2e265eb46b62295feb734a3f" ]
{"qa_id":"QA:bb0cb7cadc4d598c11588a75","qa_group_id":"QAG:7d4f5ff551992b3323ab05df","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Recently, several groups have described patient-derived colorectal...
QA:bb4fb94d991661c55e4d7169
QAG:db2991974f8d47d55768d3af
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "2018 ) surgically implanted CRC organoids into the cecum of mice, which led to tumor metastasis to the liver and lung with 100% efficiency"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:059e67f3b234cf4911e5e52b","quotes":["Fumagalli et al. ( Fumagalli et al., 2018 ) surgically implanted CRC organoi...
[ "CLM:059e67f3b234cf4911e5e52b", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:15f91bd2640e6c9aeb8aebb3" ]
[]
[]
{"qa_id":"QA:bb4fb94d991661c55e4d7169","qa_group_id":"QAG:db2991974f8d47d55768d3af","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"2018 ) surgically implanted CRC organoids into the cecum of mice, ...
QA:bd6b058b5af55f9c021ec0de
QAG:b791d19858c08842e1dc52c4
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "In all of the four enrolled GEO cohorts, the univariate Cox regression model indicated that the DRS was associated with prognosis of CRC patients in terms of OS or DSS with the P values of 8e–04 ( GSE40967 ), 0.0016 ( GSE17538 ), 0.018 ( GSE87211 ), and 0.0044 ( GSE388...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3446d7b53c282b7a429cb904","quotes":["In all of the four enrolled GEO cohorts, the univariate Cox regression model...
[ "CLM:3446d7b53c282b7a429cb904", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC9004628" ]
[ "SPAN:37a6f610daf31e14e98f77da" ]
[]
[]
{"qa_id":"QA:bd6b058b5af55f9c021ec0de","qa_group_id":"QAG:b791d19858c08842e1dc52c4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"In all of the four enrolled GEO cohorts, the univariate Cox regres...
QA:c0b00a391f309d8a0dc0add0
QAG:7ffae6e4260128d12b4f17e9
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Furthermore, we included organoid use to understand intra-tumor heterogeneity, both in terms of mutational diversification and of diversification in drug sensitivity"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5ef8a344ca03ab96e5854565","quotes":["Furthermore, we discuss organoid use to understand ...
[ "CLM:5ef8a344ca03ab96e5854565", "CLM:02ff8ab5ecc9755da71f1be3", "CLM:3a5d83a22549a75ae2253455" ]
[ "PMID:30261425", "PMCID:PMC9863259" ]
[ "SPAN:440f50b100e1b5459f0aaf55", "SPAN:1b3bc93518394d8a1ac7643d" ]
[ "ASC2:35c3818f1e17f0aa70041c9c" ]
[ "HYP:DCH:5e324cfe296e1371e62e36e0" ]
{"qa_id":"QA:c0b00a391f309d8a0dc0add0","qa_group_id":"QAG:7ffae6e4260128d12b4f17e9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Furthermore, we included organoid use to understand intra-tumor he...
QA:c2c1d91431a885742f6afe1b
QAG:b2499e81e5afb7127af4ffce
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "All patients were included before they received their last SOC treatment line (irinotecan-based therapy or anti-EGFR mABs), while all had progressed on one or two prior lines of SOC treatment (containing 5-fluoruracil, with or without oxaliplatin and/or irinotecan) acc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:afa6a51ee4aba6bffedf9faf","quotes":["All patients were included before they received their last SOC treatment lin...
[ "CLM:afa6a51ee4aba6bffedf9faf", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMCID:PMC8086019" ]
[ "SPAN:f7def0ab2bf10ef60258b302" ]
[]
[]
{"qa_id":"QA:c2c1d91431a885742f6afe1b","qa_group_id":"QAG:b2499e81e5afb7127af4ffce","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"All patients were included before they received their last SOC tre...
QA:c425ab91b800506d5af4aaac
QAG:66e1b5bc6a9e39b77721ea49
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35696669? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:35696669","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:35696669" ]
[]
[]
[]
{"qa_id":"QA:c425ab91b800506d5af4aaac","qa_group_id":"QAG:66e1b5bc6a9e39b77721ea49","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:35696669? E...
QA:c597ab2ad3f32d693de2fbfe
QAG:467b3e43b04265000cf7a76b
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "In this study, we found that the PDTO drug test was a prognostic factor for PFS in patients with stage IV CRC ( p < 0.001)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4a2f95453bf5e80e29ec6ea7","quotes":["In this study, we found that the PDTO drug test was an independent prognosti...
[ "CLM:4a2f95453bf5e80e29ec6ea7", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10072204" ]
[ "SPAN:6c44999a3b3fcba06e861359" ]
[]
[]
{"qa_id":"QA:c597ab2ad3f32d693de2fbfe","qa_group_id":"QAG:467b3e43b04265000cf7a76b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"In this study, we found that the PDTO drug test was a prognostic f...
QA:c6edef6d0a7aff1b636f6b09
QAG:1b5b2c12288cab0e54068af6
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Robust inhibition of the EGFR-RAS-ERK pathway sensitizes for navitoclax promoted cell death. ( A ) Dose-response curves of patient-derived CRC organoids P18T-KRAS G12D treated with the dual EGFR/HER2 inhibitor afatinib, MEK inhibitor selumetinib, BCL2/BCLXL inhibitor n...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6c993178b3e2e0383c815678","quotes":["10.7554/eLife.18489.034 Figure 9. Robust inhibition...
[ "CLM:6c993178b3e2e0383c815678", "CLM:0a58aec46a1065fe9c48847b", "CLM:ee5340e77d50a52ad1902b72" ]
[ "PMCID:PMC5127645", "PMCID:PMC9863259" ]
[ "SPAN:6e6fdbb34e5935f19e5a7a36", "SPAN:e626c91e06fc2cbaeb2f2891" ]
[ "ASC2:77cd8c6d6b9f76d4336bd75e" ]
[ "HYP:DCH:b2016c57488d0d60afd61f37" ]
{"qa_id":"QA:c6edef6d0a7aff1b636f6b09","qa_group_id":"QAG:1b5b2c12288cab0e54068af6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Robust inhibition of the EGFR-RAS-ERK pathway sensitizes for navit...
QA:c758e8af96183b3d8d0752ac
QAG:ed39d14861739157fd35d4ab
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Dysregulation of KRAS signaling in pancreatic cancer was not associated with KRAS mutations and outcome"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, C...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b06dd56d5e900ad96df07e77","quotes":["37. Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, et...
[ "CLM:b06dd56d5e900ad96df07e77", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMCID:PMC6457557" ]
[ "SPAN:5dc5a5f8bd53ac42a3355e0b" ]
[]
[]
{"qa_id":"QA:c758e8af96183b3d8d0752ac","qa_group_id":"QAG:ed39d14861739157fd35d4ab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Dysregulation of KRAS signaling in pancreatic cancer was not assoc...
QA:c7d0b8e5bd43a85c76d4f377
QAG:e5ad1db0cc39914abcf1f19a
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Using our network-based approach, we found that the “Gastrin-CREB signaling pathway via PKC and MAPK” pathway was associated with the response to cetuximab treatment in colorectal cancer organoids (Supplementary Fig. 11 )"? Return the original wording with paper, Claim...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f08a0998caa2a00870e5062c","quotes":["Using our network-based approach, we found that the “Gastrin-CREB signaling ...
[ "CLM:f08a0998caa2a00870e5062c", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC7599252" ]
[ "SPAN:e8c72d2cfb3b534acc50c2a4" ]
[]
[]
{"qa_id":"QA:c7d0b8e5bd43a85c76d4f377","qa_group_id":"QAG:e5ad1db0cc39914abcf1f19a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Using our network-based approach, we found that the “Gastrin-CREB ...
QA:c94617f067a1893e16acb1c7
QAG:14f32e2cba7cd5c26d0a66d1
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "For obstructive left-sided colon cancer that was not suitable for primary anastomosis after assessment, patients received diversion colostomy"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:927559fa9f39ecc9c86455e3","quotes":["For obstructive left-sided colon cancer that was not suitable for primary an...
[ "CLM:927559fa9f39ecc9c86455e3", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10072204" ]
[ "SPAN:f14fc4c68ac42bffbfc115a9" ]
[]
[]
{"qa_id":"QA:c94617f067a1893e16acb1c7","qa_group_id":"QAG:14f32e2cba7cd5c26d0a66d1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"For obstructive left-sided colon cancer that was not suitable for ...
QA:cd6217625365a00cdd9891f0
QAG:b92175a7fb0ac9336a63e965
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Patients with stage IV CRC received multidisciplinary team (MDT) consultations after hospitalization"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Clai...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9d82747f3918876e443279de","quotes":["Patients with stage IV CRC received multidisciplinary team (MDT) consultatio...
[ "CLM:9d82747f3918876e443279de", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10072204" ]
[ "SPAN:b66e27ef78ba08420fea7729" ]
[]
[]
{"qa_id":"QA:cd6217625365a00cdd9891f0","qa_group_id":"QAG:b92175a7fb0ac9336a63e965","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Patients with stage IV CRC received multidisciplinary team (MDT) c...
QA:cdd3e2166c425a7e95f88d4f
QAG:76a8d646cfa93595371ad5f8
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "The results showed that Fbxw7α overexpression decreased the 5-FU IC50 and inhibited FBXW7 mutation in mediating 5-FU drug-resistance of CRC cell lines"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: re...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4d6436d7508552c5a9d4afda","quotes":["The results showed that Fbxw7α overexpression significantly decreased the 5-...
[ "CLM:4d6436d7508552c5a9d4afda", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC4830362" ]
[ "SPAN:4091256595eb106258166195" ]
[]
[]
{"qa_id":"QA:cdd3e2166c425a7e95f88d4f","qa_group_id":"QAG:76a8d646cfa93595371ad5f8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"The results showed that Fbxw7α overexpression decreased the 5-FU I...
QA:d20453aa0a0f27b5eedb978f
QAG:c422ccc1366f6f9f7a86c073
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "2020 ) generated paired organoids derived from primary tumors and matched liver metastases in the same CRC patients and showed that inducible knockdown of SOX2 decreased invasion, proliferation, and liver metastasis outgrowth"? Return the original wording with paper, C...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e088859b00317ec93d7baf4e","quotes":["He et al. ( Li et al., 2020 ) generated paired organoids derived from primar...
[ "CLM:e088859b00317ec93d7baf4e", "CLM:1cac52e2cbd154d19265a10b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:7e62e25027222281effc7476" ]
[]
[]
{"qa_id":"QA:d20453aa0a0f27b5eedb978f","qa_group_id":"QAG:c422ccc1366f6f9f7a86c073","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"2020 ) generated paired organoids derived from primary tumors and ...
QA:d62f3f8398721499aee3a799
QAG:2b9d04c0ca165e32fce4e86c
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC5030729? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC5030729","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC5030729" ]
[]
[]
[]
{"qa_id":"QA:d62f3f8398721499aee3a799","qa_group_id":"QAG:2b9d04c0ca165e32fce4e86c","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC5030729...
QA:e08e63d11110a31ac8ad1d0f
QAG:fb8470d270bc388e4e5ef325
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "All patients were included before they received their last SOC treatment line (irinotecan-based therapy or anti-EGFR mABs), while all had progressed on one or two prior lines of SOC treatment (containing 5-fluoruracil, with or without oxaliplatin and/or irinotecan) acc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:caa55e7b31cd037fd4bf9caf","quotes":["All patients were included before they received their last SOC treatment lin...
[ "CLM:caa55e7b31cd037fd4bf9caf", "CLM:5ef8a344ca03ab96e5854565" ]
[ "PMCID:PMC8086019" ]
[ "SPAN:f7def0ab2bf10ef60258b302" ]
[]
[]
{"qa_id":"QA:e08e63d11110a31ac8ad1d0f","qa_group_id":"QAG:fb8470d270bc388e4e5ef325","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"All patients were included before they received their last SOC tre...
QA:e4454822d8bf0e247175a415
QAG:205ddde450ba01a1b584f89f
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "patient-derived organoids predicted response to chemotherapy in metastatic colorectal cancer patients"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Cla...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM_SUP:bbdaacd1e75f59f252baeffb","quotes":["Patient-derived organoids can predict response to chemotherapy in metast...
[ "CLM_SUP:bbdaacd1e75f59f252baeffb", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMCID:PMC10072204" ]
[ "SPAN_SUP:36729bc994e2055c08b7182e" ]
[]
[]
{"qa_id":"QA:e4454822d8bf0e247175a415","qa_group_id":"QAG:205ddde450ba01a1b584f89f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"patient-derived organoids predicted response to chemotherapy in me...
QA:e456ca63a673ef1a054610fc
QAG:ba05a904ed91de4ab0f2d3c3
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Treatment promoted profound organoid disintegration after 48 h as evident in phase contrast microscopy images from two patients ( Figure 5 A, colon cancer from primary site; Figure 5 B, colon cancer liver metastasis)"? Return the original wording with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3a5d83a22549a75ae2253455","quotes":["Treatment induced profound organoid disintegration ...
[ "CLM:3a5d83a22549a75ae2253455", "CLM:0a58aec46a1065fe9c48847b", "CLM:3534362f2a13bb5309c35d90" ]
[ "PMCID:PMC9863259", "PMCID:PMC4830362" ]
[ "SPAN:1b3bc93518394d8a1ac7643d", "SPAN:d2cce74a0e291981c9e35923" ]
[ "ASC2:5b92f820953cbd9124b9d32d" ]
[ "HYP:DCH:1056fefd139b574f44eeab23" ]
{"qa_id":"QA:e456ca63a673ef1a054610fc","qa_group_id":"QAG:ba05a904ed91de4ab0f2d3c3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Treatment promoted profound organoid disintegration after 48 h as ...
QA:e497926cb0759757bf77bcba
QAG:1ec2ad483db2d974c92ad7c1
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "As heterogeneity of cancer cells constituted an important parameter in the development of therapy resistance, an accurate assessment of intra-tumor heterogeneity is essential for the prediction of drug resistance and development of effective treatment"? Return the orig...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1cac52e2cbd154d19265a10b","quotes":["As heterogeneity of cancer cells constitutes an important parameter in the d...
[ "CLM:1cac52e2cbd154d19265a10b", "CLM:059e67f3b234cf4911e5e52b" ]
[ "PMID:30261425" ]
[ "SPAN:405a02f2ab4051c46f9a3e7c" ]
[]
[]
{"qa_id":"QA:e497926cb0759757bf77bcba","qa_group_id":"QAG:1ec2ad483db2d974c92ad7c1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"As heterogeneity of cancer cells constituted an important paramete...
QA:e530bf8f12052fda96f89899
QAG:3ddf1942a5ba6214bac862fc
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Importantly, engrafted tumors exhibited the heterogenous sensitivity to chemotherapy observed clinically"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:910db38e3f606d63a75a2412","quotes":["Importantly, engrafted tumors displayed the heterogenous sensitivity to chem...
[ "CLM:910db38e3f606d63a75a2412", "CLM:02ff8ab5ecc9755da71f1be3" ]
[ "PMCID:PMC7385919" ]
[ "SPAN:f51c598dc2202ecb249a4e78" ]
[]
[]
{"qa_id":"QA:e530bf8f12052fda96f89899","qa_group_id":"QAG:3ddf1942a5ba6214bac862fc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Importantly, engrafted tumors exhibited the heterogenous sensitivi...
QA:ed1b613657118480aa54a84a
QAG:7221d161e7a05f8c04aea735
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Although our RAS mutant CRC organoids showed sensitivity to dual inhibition of MEK and ERK, also this drug combination promoted cell-cycle arrest rather than cell death, questioning whether it will be sufficient for the treatment of RAS mutant CRC"? Return the original...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6627364fd1e47da0d8f06e70","quotes":["Although our RAS mutant CRC organoids showed sensit...
[ "CLM:6627364fd1e47da0d8f06e70", "CLM:0a58aec46a1065fe9c48847b", "CLM:d6cf25e9df24e15ceeac556a" ]
[ "PMCID:PMC5127645", "PMID:30261425" ]
[ "SPAN:69d5b0c787468fc7945efef2", "SPAN:d4a3832497d3396828b39d40" ]
[ "ASC2:e87b1d6b884d3b661af2a2ed" ]
[ "HYP:DCH:90312f9de861a8f28b1dc4b0" ]
{"qa_id":"QA:ed1b613657118480aa54a84a","qa_group_id":"QAG:7221d161e7a05f8c04aea735","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Although our RAS mutant CRC organoids showed sensitivity to dual i...
QA:f511189780ff7b440ef407d0
QAG:0a322a2ede14d7d7ce69a467
provenance_qa
paper_evidence_availability
provenance_qa
G014
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7760698? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC7760698","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC7760698" ]
[]
[]
[]
{"qa_id":"QA:f511189780ff7b440ef407d0","qa_group_id":"QAG:0a322a2ede14d7d7ce69a467","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G014","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7760698...
QA:f878cbe7c8065149c6be9724
QAG:bbfc80dfd47056a76b194046
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "We also observed that c-PARP expression of CRC-166T was higher than the oxaliplatin-treated M-ORG condition than in the ORG condition ( Figure 8 C and Figure S8B )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance req...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:21bf74923e863ef83e0bda9d","quotes":["We also observed that c-PARP expression of CRC-166T was significantly higher...
[ "CLM:21bf74923e863ef83e0bda9d", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC10705195" ]
[ "SPAN:6b0a0410b49a6c4ab2775a3a" ]
[]
[]
{"qa_id":"QA:f878cbe7c8065149c6be9724","qa_group_id":"QAG:bbfc80dfd47056a76b194046","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"We also observed that c-PARP expression of CRC-166T was higher tha...
QA:fe869bc6b39991972c5adceb
QAG:3a59189652a291a9ce02eb1d
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "Epithelial-mesenchymal Transition and Metastasis of colon Cancer Cells promoted by the Fak Pathway in Cancer-Associated Fibroblasts"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supp...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:17ac2f32c1ec792ca5f45e6c","quotes":["Epithelial-mesenchymal Transition and Metastasis of colon Cancer Cells Induc...
[ "CLM:17ac2f32c1ec792ca5f45e6c", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC8902504" ]
[ "SPAN:60ae2415a071b83d981361b8" ]
[]
[]
{"qa_id":"QA:fe869bc6b39991972c5adceb","qa_group_id":"QAG:3a59189652a291a9ce02eb1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"Epithelial-mesenchymal Transition and Metastasis of colon Cancer C...
QA:ff6fde2b926a720eb5c50f72
QAG:0a85227307433580dad1caa7
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "In TCGA-CRC cohort, the univariate Cox regression model revealed that the DRS was associated with prognosis of CRC patients in terms of OS ( P < 0.0001) ( Figure 6A )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:48ad4aa2bedec1ec273ee504","quotes":["The equation of DRS was finally derived: DRS = GEL (gene expression level) (...
[ "CLM:48ad4aa2bedec1ec273ee504", "CLM:0a58aec46a1065fe9c48847b" ]
[ "PMCID:PMC9004628" ]
[ "SPAN:edd23bdbb5a4190ed4c3c2fd" ]
[]
[]
{"qa_id":"QA:ff6fde2b926a720eb5c50f72","qa_group_id":"QAG:0a85227307433580dad1caa7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"In TCGA-CRC cohort, the univariate Cox regression model revealed t...
QA:ff8db14217f6dcf33a00c9c8
QAG:2b62f6de6fc98977eba0d1f1
provenance_qa
exact_evidence_retrieval
provenance_qa
G014
en
train
Which exact source passage supports the statement "TOBis mass cytometry and Trellis single-cell screening revealed that drug promoted PTM signaling responses are PDO-specific and demonstrated that CAFs shift epithelial cells toward a slow-cycling revival stem cell fate to protect CRC cells from chemotherapy"? Return the...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c35c47003f069699d7ab7f38","quotes":["TOBis mass cytometry and Trellis single-cell screening revealed\nthat drug-i...
[ "CLM:c35c47003f069699d7ab7f38", "CLM:d5cf7f03a5e8504f09acbe5f" ]
[ "PMID:38065081" ]
[ "SPAN:b0d570f1326faf9b89c0b8ff" ]
[]
[]
{"qa_id":"QA:ff8db14217f6dcf33a00c9c8","qa_group_id":"QAG:2b62f6de6fc98977eba0d1f1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G014","question":"Which exact source passage supports the statement \"TOBis mass cytometry and Trellis single-cell screening revealed th...
QA:011c318458fdc056040beb1f
QAG:4d164381754230d445ae78d7
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "In addition, overuse of chemotherapy led to unacceptable drug toxicity, and insufficient chemotherapy leads to recurrence. These are practical challenges, and finding more accurate biomarkers for monitoring and early detection of recurrence would be helpful"? Return th...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4f5c93171ed123d2c2bbe2db","quotes":["Most early-stage (tumor-node-metastasis [TNM] stage I–III) colorectal cancer...
[ "CLM:4f5c93171ed123d2c2bbe2db", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC9907993" ]
[ "SPAN:f2533f058b190bf09db800ee" ]
[]
[]
{"qa_id":"QA:011c318458fdc056040beb1f","qa_group_id":"QAG:4d164381754230d445ae78d7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"In addition, overuse of chemotherapy led to unacceptable drug toxi...
QA:0bc576b0a7c79ca14a9e85df
QAG:7a819fcf559f99050b486ef7
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "Several studies show that the presence of ctDNA after surgery was associated with a high risk of recurrence in patients with colorectal cancer, where the sensitivity could be 40–50% in predicting relapse"? Return the original wording with paper, Claim, and Evidence Spa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e9e3102cb96074d29f3ef81f","quotes":["Several studies show that the presence of ctDNA after surgery is associated ...
[ "CLM:e9e3102cb96074d29f3ef81f", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC8933829" ]
[ "SPAN:e1f30b0eb4bb0c74d8ff326a" ]
[]
[]
{"qa_id":"QA:0bc576b0a7c79ca14a9e85df","qa_group_id":"QAG:7a819fcf559f99050b486ef7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"Several studies show that the presence of ctDNA after surgery was ...
QA:153482d3b7b63cb6478b31ac
QAG:4bb3aafcf2ee8422a8ac942d
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "Purpose This study aims to evaluate the ability of perioperative circulating tumor DNA (ctDNA) to predict surgical outcome and recurrence following neoadjuvant chemoradiation for locally advanced rectal cancer (LARC)"? Return the original wording with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e911a2c710613...
[ "CLM:e911a2c710613675cfdf6dd2", "CLM:229dfdd0872b7fad8f2b5506", "CLM:e710bc0cfaf712bdc92abfba", "CLM:119163482eadac8c9e9386f8", "CLM:db4be9472583c420092f6bbc", "CLM:9ebbde126c7621674d69d567", "CLM:28722bea258d22ebbc25fe88", "CLM:13ab1a21621687d03c2a4376" ]
[ "PMCID:PMC8232395", "PMID:37992872", "PMCID:PMC9648419", "PMCID:PMC8834623" ]
[ "SPAN:e0aaeff0ad2b320f7229db65", "SPAN:959c36241af1bec4fbc9fda3", "SPAN:bc2bf1c278edfe091649ea43", "SPAN:e312f291e8489673c8c5fa0a", "SPAN:022ac90de79847e3992503a9", "SPAN:b5d23fe0f66ba7b07b7597a7", "SPAN:ebb86234894e0ad0ff02a233" ]
[ "ASC2:b48c13259f1e354a54c23043", "ASC2:d60f8a62bd05b8bd7bc8a7c8", "ASC2:ba69b243c7e00143ebcaffe3", "ASC2:c0071bb25cf636674c7df9c6" ]
[ "HYP:DCH:07df11c6c55b85340628e526", "HYP:DCH:bcda47cb549c690ff12b7c71", "HYP:DCH:233fa0c4925e4166640878ce" ]
{"qa_id":"QA:153482d3b7b63cb6478b31ac","qa_group_id":"QAG:4bb3aafcf2ee8422a8ac942d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"Purpose This study aims to evaluate the ability of perioperative c...
QA:17829199478d8fb20d72fbf3
QAG:a478228f57d0be0048a96d03
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "CEA levels were increased before initiation and decreased to the normal range during the course of chemotherapy (LB-CRC-25, Figure 4 B)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:729bb148fb4ea688bd0edc59","quotes":["CEA levels were elevated before initiation and decreased to the normal range...
[ "CLM:729bb148fb4ea688bd0edc59", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC8834623" ]
[ "SPAN:7ddb4249c41d5650d3ca369a" ]
[]
[]
{"qa_id":"QA:17829199478d8fb20d72fbf3","qa_group_id":"QAG:a478228f57d0be0048a96d03","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"CEA levels were increased before initiation and decreased to the n...
QA:17f09db6eb15323d3d5a1287
QAG:d2af09fc4eb7ecf16beb2a46
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "9%] male) were enrolled in the study"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; assess the embedded target Clai...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:83c18358647c266511e81f1f","quotes":["A total of 130 patients with International Union Against Cancer stages I to ...
[ "CLM:83c18358647c266511e81f1f", "CLM:29fd3cf8f9f161496fe05b0d" ]
[ "PMCID:PMC6512280" ]
[ "SPAN:7ba260199403f06b22638c50" ]
[]
[]
{"qa_id":"QA:17f09db6eb15323d3d5a1287","qa_group_id":"QAG:d2af09fc4eb7ecf16beb2a46","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"9%] male) were enrolled in the study\"? Return the original wordin...
QA:1ae49ba88eceb4f7726e1bfb
QAG:750ebf77edf049428a99ca1a
provenance_qa
paper_evidence_availability
provenance_qa
G015
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:33356539? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:33356539","verdict":"no_released_traceable_claim","reason":"No Cla...
[]
[ "PMID:33356539" ]
[]
[]
[]
{"qa_id":"QA:1ae49ba88eceb4f7726e1bfb","qa_group_id":"QAG:750ebf77edf049428a99ca1a","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G015","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:33356539? E...
QA:1f4021e32f21c9be9ea1d932
QAG:055e50d565788df5641feb12
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "Circulating tumor DNA analysis detects minimal residual disease and predicted recurrence in patients with stage II colon cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporti...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e710bc0cfaf712bdc92abfba","quotes":["REFERENCES\n1. Tie J, Wang Y , Tomasetti C, et al. ...
[ "CLM:e710bc0cfaf712bdc92abfba", "CLM:229dfdd0872b7fad8f2b5506", "CLM:a118f799485bb93be90c4cfd" ]
[ "PMID:37992872", "PMCID:PMC10523996" ]
[ "SPAN:959c36241af1bec4fbc9fda3", "SPAN:cb2e9c50b10b6f0ee95f9c61" ]
[ "ASC2:5cdeb1a3fe282253527902be" ]
[ "HYP:DCH:a53dfe4380d2e1ac68a227d7" ]
{"qa_id":"QA:1f4021e32f21c9be9ea1d932","qa_group_id":"QAG:055e50d565788df5641feb12","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"Circulating tumor DNA analysis detects minimal residual disease an...
QA:21e70c566da4ce8b5d0ce868
QAG:d7fff81313bad48b4712d911
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "Detection of potential CRC driver gene mutations after nCRT was associated with a much worse RFS (hazard ratio [HR]: 9.29; 95% CI: 3.74 to 23.10, P < 0.001; Fig 4C )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0fb0860641c822585ffc2b74","quotes":["Detection of potential CRC driver gene mutations af...
[ "CLM:0fb0860641c822585ffc2b74", "CLM:229dfdd0872b7fad8f2b5506", "CLM:47c2baa4cc92e7fe13347a1f" ]
[ "PMCID:PMC8407540", "PMCID:PMC8983807" ]
[ "SPAN:fedea72ce8b85358815bc94f", "SPAN:03c191db52ebbe0a07d442c0" ]
[ "ASC2:8cf27883adeb886139122117" ]
[]
{"qa_id":"QA:21e70c566da4ce8b5d0ce868","qa_group_id":"QAG:d7fff81313bad48b4712d911","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"Detection of potential CRC driver gene mutations after nCRT was as...
QA:23d688519342ed2e85decd01
QAG:712a29fefc309e97b7069283
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "CEA levels were increased before the initiation of chemotherapy and decreased to the normal range approximately 1.5 months after ctDNA became undetectable for the first time (LB-CRC-32, Supplementary Figure S26 )"? Return the original wording with paper, Claim, and Evi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:431f460f1d7ae80b64730936","quotes":["CEA levels were elevated before the initiation of chemotherapy and decreased...
[ "CLM:431f460f1d7ae80b64730936", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC8834623" ]
[ "SPAN:983f9bf83768b7caa06fc9bf" ]
[]
[]
{"qa_id":"QA:23d688519342ed2e85decd01","qa_group_id":"QAG:712a29fefc309e97b7069283","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"CEA levels were increased before the initiation of chemotherapy an...
QA:278f93ea6720cedd1bcad211
QAG:d20be6abafe92af7915083e9
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "A total of 879 CRC patients were included in the 8 studies"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; assess th...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eb3e83e399166868ffa95029","quotes":["A total of 879 CRC patients were included in the 8 studies."],"citations":[{...
[ "CLM:eb3e83e399166868ffa95029", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC8983807" ]
[ "SPAN:b2ba1c106ba4b544c1ed31bc" ]
[]
[]
{"qa_id":"QA:278f93ea6720cedd1bcad211","qa_group_id":"QAG:d20be6abafe92af7915083e9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"A total of 879 CRC patients were included in the 8 studies\"? Retu...
QA:2f27711278ddf2705a1f4721
QAG:8c43b82a67f6daf8b37573b4
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "The methylation signals of ctDNA was higher than the CRC patients than in the healthy controls"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4b63c8ae957ab55efa99d6dc","quotes":["The methylation signals of ctDNA were significantly higher in the CRC patien...
[ "CLM:4b63c8ae957ab55efa99d6dc", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC7865146" ]
[ "SPAN:55724700146eb38b8c844d68" ]
[]
[]
{"qa_id":"QA:2f27711278ddf2705a1f4721","qa_group_id":"QAG:8c43b82a67f6daf8b37573b4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"The methylation signals of ctDNA was higher than the CRC patients ...
QA:2f4bc4836175cf5fa475007b
QAG:2ab738fa47838d1b490aac4f
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "1 Despite improved surgery, implementation of screening, and advances in treatment regimens, the 5-year mortality rate for patients with CRC remains high at approximately 40%, thereby representing a significant global health burden"? Return the original wording with pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e85662e5e2153da46005fa3d","quotes":["1 Despite improved surgery, implementation of screening, and advances in tre...
[ "CLM:e85662e5e2153da46005fa3d", "CLM:29fd3cf8f9f161496fe05b0d" ]
[ "PMCID:PMC6512280" ]
[ "SPAN:91a3f245b9445c3fe21a155b" ]
[]
[]
{"qa_id":"QA:2f4bc4836175cf5fa475007b","qa_group_id":"QAG:2ab738fa47838d1b490aac4f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"1 Despite improved surgery, implementation of screening, and advan...
QA:3445853b3a28dbad1c7ac15a
QAG:0ff6de2a76e8a6a023087643
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "Circulating tumor DNA analysis detects minimal residual disease and predicted recurrence in patients with stage II colon cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporti...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31f9225d716a08deb7775bb2","quotes":["13. Tie J, Wang Y, Tomaset...
[ "CLM:31f9225d716a08deb7775bb2", "CLM:229dfdd0872b7fad8f2b5506", "CLM:119163482eadac8c9e9386f8", "CLM:a118f799485bb93be90c4cfd", "CLM:9ebbde126c7621674d69d567", "CLM:db4be9472583c420092f6bbc" ]
[ "PMCID:PMC8407540", "PMCID:PMC9648419", "PMCID:PMC10523996", "PMID:37992872" ]
[ "SPAN:86859fcabd21187d92d44db3", "SPAN:bc2bf1c278edfe091649ea43", "SPAN:022ac90de79847e3992503a9", "SPAN:cb2e9c50b10b6f0ee95f9c61", "SPAN:e312f291e8489673c8c5fa0a" ]
[ "ASC2:cc590080a43143dca9649e89", "ASC2:c132ce43af6390f2d10dea8f", "ASC2:c80ff42c6782abf03ce13859" ]
[ "HYP:DCH:43e90159d4e19ea68eb3a090", "HYP:DCH:23b735767c3417ebfa72737e" ]
{"qa_id":"QA:3445853b3a28dbad1c7ac15a","qa_group_id":"QAG:0ff6de2a76e8a6a023087643","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"Circulating tumor DNA analysis detects minimal residual disease an...
QA:3716360968e1ae54f32d7ca6
QAG:7a6405a23edcfa0db1e3ada8
provenance_qa
exact_evidence_retrieval
provenance_qa
G015
en
train
Which exact source passage supports the statement "In 2016, the Epi ProColon biomarker assay detecting SEPT9 methylation received FDA approval as a CRC screening test"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage w...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:16b9222662d59ebea0beeaac","quotes":["In 2016, the Epi ProColon biomarker assay detecting SEPT9 methylation receiv...
[ "CLM:16b9222662d59ebea0beeaac", "CLM:229dfdd0872b7fad8f2b5506" ]
[ "PMCID:PMC9101623" ]
[ "SPAN:514f60699322427cbb4adaac" ]
[]
[]
{"qa_id":"QA:3716360968e1ae54f32d7ca6","qa_group_id":"QAG:7a6405a23edcfa0db1e3ada8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G015","question":"Which exact source passage supports the statement \"In 2016, the Epi ProColon biomarker assay detecting SEPT9 methylat...