qa_id stringlengths 27 27 | qa_group_id stringlengths 28 32 | qa_family stringclasses 3
values | subtask_type stringclasses 7
values | qa_subtype stringclasses 3
values | cluster_id stringclasses 42
values | language stringclasses 1
value | split stringclasses 1
value | question stringlengths 148 1.41k | answer stringlengths 718 10.8k | claim_ids listlengths 0 8 | paper_ids listlengths 1 5 | evidence_span_ids listlengths 0 7 | association_ids listlengths 0 4 | hypothesis_ids listlengths 0 4 | record_json stringlengths 4.37k 33.7k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QA:16f970efa25345b1d15d989d | QAG:8960791aaabf78dcc788eb0d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Most recently, a randomized Phase II study demonstrated that the addition of hydroxychloroquine to neoadjuvant gemcitabine and nab-paclitaxel chemotherapy in patients with resectable PDAC led to inhibition of autophagy and resulting improved response, indicating the im... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:09032e4ec808d0edf1396f6b","quotes":["Most recently, a randomized Phase II study demonstr... | [
"CLM:09032e4ec808d0edf1396f6b",
"CLM:03219ae941a2b333b95944b3",
"CLM:1a3fd2aadf01c726b8689a42"
] | [
"PMCID:PMC10457905",
"PMID:35617803"
] | [
"SPAN:c144e7b4fe32fe93679f313e",
"SPAN:784063bda7f1d2022244654d"
] | [
"ASC2:699e840621ccdc6948951557"
] | [
"HYP:DCH:c3ea95972abd51a35c24f328"
] | {"qa_id":"QA:16f970efa25345b1d15d989d","qa_group_id":"QAG:8960791aaabf78dcc788eb0d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Most recently, a randomized Phase II study demonstrated that the a... |
QA:17960df213e0990dcc88c859 | QAG:fa7adbd20bddf0ac34cda9a0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Overall, the above results indicate that high PYGL expression was correlated with more aggressive behaviors in PDAC patients and predicts a poor prognosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9dc7cc296fe25f35ff8b6376","quotes":["Overall, the above results indicate that high PYGL expression is correlated ... | [
"CLM:9dc7cc296fe25f35ff8b6376",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:087a8d48170fd8492a9a5dcd"
] | [] | [] | {"qa_id":"QA:17960df213e0990dcc88c859","qa_group_id":"QAG:fa7adbd20bddf0ac34cda9a0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Overall, the above results indicate that high PYGL expression was ... |
QA:17c09311ae2066c9699a608e | QAG:80c78adb5c853249df295295 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "5 LIPH-LPA-LPAR axis increased PDAC glycolysis and viability by activating hypoxia and Hippo pathway"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Clai... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6494733286e0c334b5eabde7","quotes":["Fig. 5 LIPH-LPA-LPAR axis enhanced PDAC glycolysis and viability by activati... | [
"CLM:6494733286e0c334b5eabde7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:dd4793b2d13d77bae4e6a10d"
] | [] | [] | {"qa_id":"QA:17c09311ae2066c9699a608e","qa_group_id":"QAG:80c78adb5c853249df295295","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"5 LIPH-LPA-LPAR axis increased PDAC glycolysis and viability by ac... |
QA:182548a072900d5ca2743b5d | QAG:a75d69209be001690392371f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Autophagy is additionally promoted in PDAC cells after gemcitabine treatment, highlighting the importance of autophagic flux in acquiring resistance to gemcitabine in pancreatic cancer tumor cells"? Return the original wording with paper, Claim, and Evidence Span refer... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:288b57c3de53065fa663b218","quotes":["Autophagy is additionally induced in PDAC cells after gemcitabine treatment,... | [
"CLM:288b57c3de53065fa663b218",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:f82312412aabac39f936677c"
] | [] | [] | {"qa_id":"QA:182548a072900d5ca2743b5d","qa_group_id":"QAG:a75d69209be001690392371f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Autophagy is additionally promoted in PDAC cells after gemcitabine... |
QA:183387bb58ac596f53f059be | QAG:95ab7803106933bcbed0e926 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Complete deletion of the stroma led to pancreatic cancer progression, demonstrating that stromal compartments can also have anti-tumoral functions"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f378a0273a8cf103d471b78b","quotes":["Complete deletion of the stroma leads to pancreatic cancer progression, demo... | [
"CLM:f378a0273a8cf103d471b78b",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8611647"
] | [
"SPAN:5c24f735258f1aab5e9f1819"
] | [] | [] | {"qa_id":"QA:183387bb58ac596f53f059be","qa_group_id":"QAG:95ab7803106933bcbed0e926","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Complete deletion of the stroma led to pancreatic cancer progressi... |
QA:18c9bd7381037f6ccb7f3734 | QAG:4e76dd3c49e2ec59e97a9bf7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "showed that activation of the RAGE signaling pathway also led to NF-κB signaling in human (Panc-1) and murine (KPC) pancreatic cancer cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ex... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e34d8811cf0fb4ba2361fe74","quotes":["Recently, Azizan et al. showed that activation of the RAGE signaling pathway... | [
"CLM:e34d8811cf0fb4ba2361fe74",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8067004"
] | [
"SPAN:2778ff7aaf260de64c91eeaf"
] | [] | [] | {"qa_id":"QA:18c9bd7381037f6ccb7f3734","qa_group_id":"QAG:4e76dd3c49e2ec59e97a9bf7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"showed that activation of the RAGE signaling pathway also led to N... |
QA:1e2bdb91fc43307592f345d1 | QAG:c522bfb7a53e57512198c0a7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC cells treated with 10 μM AXP-3009 or AXP-3019 for 48 h show increased binding with annexin V, indicating increased externalization of phosphatidylserine and apoptotic cell death"? Return the original wordi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7051a0c037611db56609f232","quotes":["As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC cells treate... | [
"CLM:7051a0c037611db56609f232",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:1bbea122533245abb7be9427"
] | [] | [] | {"qa_id":"QA:1e2bdb91fc43307592f345d1","qa_group_id":"QAG:c522bfb7a53e57512198c0a7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC ce... |
QA:1eeea8a88cf258d0cfac8b9e | QAG:6e2f52ce94f711d7c51fcf00 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "5 C and D), which could be decreased by CA-AKT ( Fig. 5 E and F)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; ass... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:284236d867367282700c39ce","quotes":["ECON failed to induce elevation of LC3-II levels and LC3 puncta accumulation... | [
"CLM:284236d867367282700c39ce",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:36af4a6ad40aabad401758a1"
] | [] | [] | {"qa_id":"QA:1eeea8a88cf258d0cfac8b9e","qa_group_id":"QAG:6e2f52ce94f711d7c51fcf00","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"5 C and D), which could be decreased by CA-AKT ( Fig. 5 E and F)\"... |
QA:1f08b7b85483c0964f1d66a0 | QAG:2cd50d9694977e8ca4c30c6a | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "The expression of ki67 was decreased in sh1-LIPH pancreatic cancer tumors, and the apoptosis marker, TUNEL, was increased (Fig. 3 D, E)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:53d2186d395467808abe3913","quotes":["The expression of ki67 was decreased in sh1-LIPH pancreatic cancer tumors, a... | [
"CLM:53d2186d395467808abe3913",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:cedc9c4a12c535f6ed98d5d2"
] | [] | [] | {"qa_id":"QA:1f08b7b85483c0964f1d66a0","qa_group_id":"QAG:2cd50d9694977e8ca4c30c6a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"The expression of ki67 was decreased in sh1-LIPH pancreatic cancer... |
QA:1f20a3b64d7b48ffc6712c3f | QAG:5feac244c7868e9629ebcde2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Actually, this massive increase in autophagosomes induced by ECON has gone far beyond the scope of what PDAC cells could withstand, possibly moving the controlled, pro-survival autophagy into an uncontrolled, pro-death mechanism in which lysosomal scavenging pathways w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:44b2a3d0231034276cb418b4","quotes":["Actually, this massive increase in autophagosomes induced by ECON has gone f... | [
"CLM:44b2a3d0231034276cb418b4",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:b387a272d481d1a761a0ee9d"
] | [] | [] | {"qa_id":"QA:1f20a3b64d7b48ffc6712c3f","qa_group_id":"QAG:5feac244c7868e9629ebcde2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Actually, this massive increase in autophagosomes induced by ECON ... |
QA:1fee325ff83053b7811110ea | QAG:9321515f2f29e2b9fed5c8a9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure S2: CQ reduces basal and AXP-3019 promoted autophagy in PDAC cell lines"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31c353d5b668acfd89184255","quotes":["Figure S1: Effect of GAPDH knock-down and 3-bromo-isoxazoline-derivative AXP... | [
"CLM:31c353d5b668acfd89184255",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:f9adf0aa377ff1c0d86898bc"
] | [] | [] | {"qa_id":"QA:1fee325ff83053b7811110ea","qa_group_id":"QAG:9321515f2f29e2b9fed5c8a9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure S2: CQ reduces basal and AXP-3019 promoted autophagy in PDA... |
QA:2072bcc5fde1dad97a14b01d | QAG:9b9986bbcffdd5c5e2abcc5a | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 2 OBP-702 induces immunogenic cell death with ATP release in human PDAC cells (A and B) Human PDAC cells with WT-p53 (A) and mt-p53 (B) received OBP-301 or OBP-702 at the indicated MOI for 48 h"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3b9e2dc0699c940aebb0f8ad","quotes":["Figure 2 OBP-702 induces immunogenic cell death with ATP release in human PD... | [
"CLM:3b9e2dc0699c940aebb0f8ad",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:aafcf96a35b783f43c2cc52e"
] | [] | [] | {"qa_id":"QA:2072bcc5fde1dad97a14b01d","qa_group_id":"QAG:9b9986bbcffdd5c5e2abcc5a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 2 OBP-702 induces immunogenic cell death with ATP release i... |
QA:2235a796df7b5b3c0bce0cd8 | QAG:aacb203e00996cc88643067f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "This shift was associated with hypoxia-driven formation of lipid droplets containing triacylglycerols and cholesterol esters 54 , with concomitant decrease in free fatty acid concentration in plasma 55 and tumor tissues 56 stemming from attenuated expression of lipolyt... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d3e9eb98944303ad0f7531f7","quotes":["This shift is associated with hypoxia-driven formation of lipid droplets con... | [
"CLM:d3e9eb98944303ad0f7531f7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8901637"
] | [
"SPAN:60f83799e786c68b6ce9b73a",
"SPAN:92faab7f7851ce07d26a404e"
] | [] | [] | {"qa_id":"QA:2235a796df7b5b3c0bce0cd8","qa_group_id":"QAG:aacb203e00996cc88643067f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"This shift was associated with hypoxia-driven formation of lipid d... |
QA:23c629b66213f31d8ed89b3b | QAG:5bedd42878f8d50379394a3c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Additionally, gbcxMRS predicted the immune classical type, a benign subtype of PDAC, with relatively high accuracy (AUC = 73%, Figure 7 c, middle panel)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3e2407254e7e4a3930158fe2","quotes":["Additionally, gbcxMRS predicted the immune classical type, a benign subtype ... | [
"CLM:3e2407254e7e4a3930158fe2",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:fecd19e899549bb4da88169b"
] | [] | [] | {"qa_id":"QA:23c629b66213f31d8ed89b3b","qa_group_id":"QAG:5bedd42878f8d50379394a3c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Additionally, gbcxMRS predicted the immune classical type, a benig... |
QA:28e610abe2debe63ccc31bbc | QAG:3b4ff812b09a2ce6995dedad | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and was associated with an Immunosuppressed Tumor Microenvironment"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exac... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f4c7b46cbf18259d1dfc042e","quotes":["63. Abou Khouzam R., Rao S.P., Venkatesh G.H., Zeinelabdin N.A., Buart S., M... | [
"CLM:f4c7b46cbf18259d1dfc042e",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:3949ae1a8ba6fb3d4699f5a2"
] | [] | [] | {"qa_id":"QA:28e610abe2debe63ccc31bbc","qa_group_id":"QAG:3b4ff812b09a2ce6995dedad","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Ca... |
QA:2a6c2c9236117c8a2730832c | QAG:f3dbcff28db2e93e9e440f3b | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 6 To further address whether ER stress inhibited PDAC cell growth by inducing apoptosis, we conducted immunoblot and immunohistochemical analyses and found that the expression of apoptosis markers was increased in response to ECON ( Fig. 6 K and L)"? Return the ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d6663b3a96425c8462e05dd3","quotes":["Figure 6 To further address whether ER stress inhibited PDAC cell growth by ... | [
"CLM:d6663b3a96425c8462e05dd3",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:7972a321fb124d3e875fd0b2"
] | [] | [] | {"qa_id":"QA:2a6c2c9236117c8a2730832c","qa_group_id":"QAG:f3dbcff28db2e93e9e440f3b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 6 To further address whether ER stress inhibited PDAC cell ... |
QA:2ad503b5a8361ea64111118b | QAG:a406a9383e794d42ecd898bf | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Insufficient vascularization also led to hypoxia, an important component of the PDAC microenvironment, which further stimulates CAFs to release matrix proteins and a large repertoire of soluble factors capable of affecting cancer cells"? Return the original wording wit... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e1d90e9bff649bf5a9a55966","quotes":["Insufficient vascularization also leads to hypoxia, an important component o... | [
"CLM:e1d90e9bff649bf5a9a55966",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997741"
] | [
"SPAN:71d0fd17fe33c90a97dc5f2e"
] | [] | [] | {"qa_id":"QA:2ad503b5a8361ea64111118b","qa_group_id":"QAG:a406a9383e794d42ecd898bf","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Insufficient vascularization also led to hypoxia, an important com... |
QA:2caa5bfc6391beaef80dff7e | QAG:b62ee0973c8e849117889019 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Autophagy inhibition increased the anti-tumor effect of cisplatin on drug-resistant esophageal cancer cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with pape... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b7b0744fc14f976d6ab3218e","quotes":["Autophagy inhibition increased the anti-tumor effect of cisplatin on drug-re... | [
"CLM:b7b0744fc14f976d6ab3218e",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:fc9d534c4e1490748699a43c"
] | [] | [] | {"qa_id":"QA:2caa5bfc6391beaef80dff7e","qa_group_id":"QAG:b62ee0973c8e849117889019","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Autophagy inhibition increased the anti-tumor effect of cisplatin ... |
QA:2d08c2238b8fabdb8f179870 | QAG:b29de1b614e81eda013cdeee | provenance_qa | paper_evidence_availability | provenance_qa | G020 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:34725193? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:34725193","verdict":"no_released_traceable_claim","reason":"No Cla... | [] | [
"PMID:34725193"
] | [] | [] | [] | {"qa_id":"QA:2d08c2238b8fabdb8f179870","qa_group_id":"QAG:b29de1b614e81eda013cdeee","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G020","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:34725193? E... |
QA:2d127a6c3d50eae161b48557 | QAG:8bea5bf2631d33ee2ac4d2a7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In the current study, gene expression profiling and immunoblotting analyses of PDAC-derived tumor xenografts indicate that administration of ( R , S ′)-MNF decreased gene and protein expression of HIF-1α and c-Myc and attenuated gene expression of multiple components o... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7015a288d03004e24b191a90","quotes":["In the current study, gene expression profiling and immunoblotting analyses ... | [
"CLM:7015a288d03004e24b191a90",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8901637"
] | [
"SPAN:aa5d586cfcdf792441d7d474"
] | [] | [] | {"qa_id":"QA:2d127a6c3d50eae161b48557","qa_group_id":"QAG:8bea5bf2631d33ee2ac4d2a7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In the current study, gene expression profiling and immunoblotting... |
QA:2d75e0f95edc9c7d48d2fdc1 | QAG:b9a639b986589af086a7df39 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "The exposure of pancreatic cancer cells to gemcitabine generally led to the stimulation of apoptosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Clai... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a8b43b6069fa72a3e9fae84e","quotes":["The exposure of pancreatic cancer cells to gemcitabine generally leads to th... | [
"CLM:a8b43b6069fa72a3e9fae84e",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8067004"
] | [
"SPAN:4735a5abb4319466e0c7102f"
] | [] | [] | {"qa_id":"QA:2d75e0f95edc9c7d48d2fdc1","qa_group_id":"QAG:b9a639b986589af086a7df39","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"The exposure of pancreatic cancer cells to gemcitabine generally l... |
QA:2de2b9dc327fa934152acfeb | QAG:b2523aa1cf3d9e6d8369e4e0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "The autophagy inhibitor verteporfin, for instance, only moderately increased the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model , and while recent clinical studies have had positive results, others have fared only moderately"? Return the ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:21b6dd22cfa5dc52b7cbb4d0","quotes":["The autophagy inhibitor verteporfin, for instance, only moderately enhanced ... | [
"CLM:21b6dd22cfa5dc52b7cbb4d0",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:bc649b2bddaece0f2e9d115e"
] | [] | [] | {"qa_id":"QA:2de2b9dc327fa934152acfeb","qa_group_id":"QAG:b2523aa1cf3d9e6d8369e4e0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"The autophagy inhibitor verteporfin, for instance, only moderately... |
QA:3459dc0a7624b35cde6adf2a | QAG:5dae52aebb5c430a2414c5f0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Compared with SCD low CAFs, SCD high CAFs improved the viability of Mia-PaCa2, a SCD high pancreatic cancer cell line, in the zPDX models treated by GEM, TGO, and DDP; SCD high CAFs also significantly improved the viability of SW1990, a SCD low pancreatic cancer cell l... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:22c4d5855e1f9d32cc71d15e","quotes":["Compared with SCD low CAFs, SCD high CAFs significantly improved the viabili... | [
"CLM:22c4d5855e1f9d32cc71d15e",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9794976"
] | [
"SPAN:20d91e9b74e366a2745a0a18"
] | [] | [] | {"qa_id":"QA:3459dc0a7624b35cde6adf2a","qa_group_id":"QAG:5dae52aebb5c430a2414c5f0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Compared with SCD low CAFs, SCD high CAFs improved the viability o... |
QA:34e74807dc00d394e15faa5f | QAG:611520480d2b93e8e81d0f7d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Consistently, decreased ATF3 expression was correlated with poor differentiation and shorter overall survival in PDAC patients ( Fig. 4 P and Q)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return t... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:36df35ed2de89817a95187ce","quotes":["Consistently, decreased ATF3 expression was correlated with poor differentia... | [
"CLM:36df35ed2de89817a95187ce",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:fdb6764d3db2d1c6f947b541"
] | [] | [] | {"qa_id":"QA:34e74807dc00d394e15faa5f","qa_group_id":"QAG:611520480d2b93e8e81d0f7d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Consistently, decreased ATF3 expression was correlated with poor d... |
QA:35777e074f0c7df7548b995f | QAG:cf3f3be3bd7b67e1a5cb571f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Pancreatic cancer has the lowest survival rate of all cancers and is predicted to become the 2nd leading cause of cancer death by 2030"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact s... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:03219ae941a2b333b95944b3","quotes":["Pancreatic cancer has the lowest survival rate of all cancers and is predict... | [
"CLM:03219ae941a2b333b95944b3",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8611647"
] | [
"SPAN:1555d554e66f34183ce89951"
] | [] | [] | {"qa_id":"QA:35777e074f0c7df7548b995f","qa_group_id":"QAG:cf3f3be3bd7b67e1a5cb571f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Pancreatic cancer has the lowest survival rate of all cancers and ... |
QA:3588f66925b362c002561cd3 | QAG:598b1eaed347860933ed506e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Last, we found that high phospho-MK2 expression in tumors was associated with poorer survival of patients with PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5ca9809d25c18c81188eca01","quotes":["Last, we found that high phospho-MK2 expression in tumors was associated wit... | [
"CLM:5ca9809d25c18c81188eca01",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9475471"
] | [
"SPAN:beb282c337ac6e53e750da75"
] | [] | [] | {"qa_id":"QA:3588f66925b362c002561cd3","qa_group_id":"QAG:598b1eaed347860933ed506e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Last, we found that high phospho-MK2 expression in tumors was asso... |
QA:36854fb3a37f73669dc8a97b | QAG:f29c16671e7659147344c830 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In line with these previous studies, we found that ECON treatment significantly upregulated the intracellular ROS levels of PDAC cells, accompanied by increased expression of Nrf2 in a dose-dependent manner ( Supporting Information Fig. S6A and S6B )"? Return the origi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f465e84b02e83dfdd149b6c3","quotes":["In line with these previous studies, we found that ECON treatment significan... | [
"CLM:f465e84b02e83dfdd149b6c3",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:0527b0dfb625ed9cda3a2496"
] | [] | [] | {"qa_id":"QA:36854fb3a37f73669dc8a97b","qa_group_id":"QAG:f29c16671e7659147344c830","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In line with these previous studies, we found that ECON treatment ... |
QA:3705daecb33047444fdb1a2f | QAG:7656333bc75fd8c2f170aabb | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "G Representative images of LIPH expression in tumor tissues from PDAC patients who received preoperative 18F-FDG PET/CT examination"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supp... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a5700f91eb9bcf1395135b11","quotes":["G Representative images of LIPH expression in tumor tissues from PDAC patien... | [
"CLM:a5700f91eb9bcf1395135b11",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:87efcc0a4b54d98ab59fa9b2"
] | [] | [] | {"qa_id":"QA:3705daecb33047444fdb1a2f","qa_group_id":"QAG:7656333bc75fd8c2f170aabb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"G Representative images of LIPH expression in tumor tissues from P... |
QA:385b4c0786b788f9a3215396 | QAG:377f8f12603d1b43725bf982 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In fact, knockout of the Nmu gene in mice led to a significant increase in the percentages and absolute numbers of CD8 + T cells and CD4 + T cells, but a decrease in the percentage and number of MDSCs in both tumor tissues (Figure 3A ; Figure S3 ) and the spleen (Figur... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0254266c32c41ab5d504f862","quotes":["In fact, knockout of the Nmu gene in mice resulted ... | [
"CLM:0254266c32c41ab5d504f862",
"CLM:03219ae941a2b333b95944b3",
"CLM:b4b5401ed26edc91d5745e3f"
] | [
"PMCID:PMC10859610",
"PMCID:PMC9513735"
] | [
"SPAN:a22c925ab8f704f304ed741c",
"SPAN:f00a2def3b779199bdbb4230"
] | [
"ASC2:d9fc99178775842702f438a9"
] | [
"HYP:DCH:e5a66d56fdc27def6dd29cc4"
] | {"qa_id":"QA:385b4c0786b788f9a3215396","qa_group_id":"QAG:377f8f12603d1b43725bf982","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In fact, knockout of the Nmu gene in mice led to a significant inc... |
QA:38e33651d57d6a0346d63978 | QAG:99d8eac581d826e8b5dd5b3c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 3 OBP-702 induces immunogenic cell death with HMGB1 release in human PDAC cells (A and B) Human PDAC cells with WT-p53 (A) and mt-p53 (B) received OBP-301 or OBP-702 at the indicated MOI for 48 h"? Return the original wording with paper, Claim, and Evidence Span... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2d7213191cf51e41029148d7","quotes":["Figure 3 OBP-702 induces immunogenic cell death with HMGB1 release in human ... | [
"CLM:2d7213191cf51e41029148d7",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:01ef4b512dbaad0f2f7b1276"
] | [] | [] | {"qa_id":"QA:38e33651d57d6a0346d63978","qa_group_id":"QAG:99d8eac581d826e8b5dd5b3c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 3 OBP-702 induces immunogenic cell death with HMGB1 release... |
QA:3904e3cbfda84af1cf719fef | QAG:0ca2e8e88ba325540c2287df | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Western blot analysis demonstrated that OBP-702 increased the expression of p53, E1A, and cleaved PARP in all human PDAC cells, whereas OBP-301 increased the expression of E1A ( Figures 4 A and 4B)"? Return the original wording with paper, Claim, and Evidence Span refe... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:42a57e0aea0cccb477318bec","quotes":["Western blot analysis demonstrated that OBP-702 increased the expression of ... | [
"CLM:42a57e0aea0cccb477318bec",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:78ef5fb0c505c8cbdbe2486b"
] | [] | [] | {"qa_id":"QA:3904e3cbfda84af1cf719fef","qa_group_id":"QAG:0ca2e8e88ba325540c2287df","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Western blot analysis demonstrated that OBP-702 increased the expr... |
QA:3956530f5b007b79c107c04a | QAG:500c46ac3177db1825d0230b | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "5 SNIPER-11 increased the efficacy of gemcitabine in PDAC. ( A, B ) SNIPER-11 increased gemcitabine induced Panc-1 or GR2000 cell apoptosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ex... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e27c7a887bae3934002e9fb2","quotes":["Fig. 5 SNIPER-11 enhanced the efficacy of gemcitabine in PDAC. ( A, B ) SNIP... | [
"CLM:e27c7a887bae3934002e9fb2",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:87d4ca4bacfbf44ffb591cfc"
] | [] | [] | {"qa_id":"QA:3956530f5b007b79c107c04a","qa_group_id":"QAG:500c46ac3177db1825d0230b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"5 SNIPER-11 increased the efficacy of gemcitabine in PDAC. ( A, B ... |
QA:39e36376f7043528b2409148 | QAG:aa1970477dddf9faedd17614 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "7 G, when the tumor volumes reached ∼100 mm 3 , mice bearing PDAC xenografts were randomly divided into 6 groups and received the following treatments: i) vehicle; ii) 25 mg/kg ECON; iii) 25 mg/kg CQ; iv) 1 mg/kg trametinib; v) 25 mg/kg ECON+1 mg/kg trametinib; and vi)... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7f3989872441f6097638d211","quotes":["In Fig. 7 G, when the tumor volumes reached ∼100 mm 3 , mice bearing PDAC xe... | [
"CLM:7f3989872441f6097638d211",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:cccca1ef19ba27740ef6807f"
] | [] | [] | {"qa_id":"QA:39e36376f7043528b2409148","qa_group_id":"QAG:aa1970477dddf9faedd17614","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"7 G, when the tumor volumes reached ∼100 mm 3 , mice bearing PDAC ... |
QA:3ac4a4312833a538dd4f06f9 | QAG:ed15a03c5f772fb41a83cfe8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "As expected, we showed that ECON treatment decreased the in vitro production of ID-1 at both the mRNA and protein levels ( Fig. 5 J and K), mirroring the effect of exogenous ATF3 expression on PDAC cells ( Fig. 5 L)"? Return the original wording with paper, Claim, and ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ee2c2f13cf0339641a04647c","quotes":["As expected, we showed that ECON treatment decreased the in vitro production... | [
"CLM:ee2c2f13cf0339641a04647c",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:82107d5b56ed47f383016aa1"
] | [] | [] | {"qa_id":"QA:3ac4a4312833a538dd4f06f9","qa_group_id":"QAG:ed15a03c5f772fb41a83cfe8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"As expected, we showed that ECON treatment decreased the in vitro ... |
QA:3bae39670c7e9e344cd2245c | QAG:9aa7763c2a2ba769b00e06d5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "4 F and G, the expression of phosphorylated AKT (p-AKT), mTOR, and P70S6K was decreased in ECON-treated PDAC cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage wi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c3849ed373a7ce51890b8e21","quotes":["As shown in Fig. 4 F and G, the expression of phosphorylated AKT (p-AKT), mT... | [
"CLM:c3849ed373a7ce51890b8e21",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:b8d8c7e773568e94bffbb524"
] | [] | [] | {"qa_id":"QA:3bae39670c7e9e344cd2245c","qa_group_id":"QAG:9aa7763c2a2ba769b00e06d5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"4 F and G, the expression of phosphorylated AKT (p-AKT), mTOR, and... |
QA:3cd042a3f467b904e261f41d | QAG:251e524a5122f3b80d08d23e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In this study, we found that TRIM11 expression was higher than PDAC cells and tissues"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7d42645ee6c91d68d9281853","quotes":["In this study, we found that TRIM11 expression were higher in PDAC cells and... | [
"CLM:7d42645ee6c91d68d9281853",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMID:33629745"
] | [
"SPAN:845df7b0c03200ce61fc22e7"
] | [] | [] | {"qa_id":"QA:3cd042a3f467b904e261f41d","qa_group_id":"QAG:251e524a5122f3b80d08d23e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In this study, we found that TRIM11 expression was higher than PDA... |
QA:41d4569af31232fe78e9a4aa | QAG:5f590f865610aac435559442 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "MK-1775 in combination with x-rays inhibited the tumor growth of MIA PaCa-2 xenografts compared with other treatment groups, including radiation or drug exposure alone, to enhance the radiosensitivity of PDAC cells in vivo"? Return the original wording with paper, Clai... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e85e87b35f43388ff5489b66","quotes":["MK-1775 in combination wit... | [
"CLM:e85e87b35f43388ff5489b66",
"CLM:03219ae941a2b333b95944b3",
"CLM:34fe77ea0f1d3337192b1a23",
"CLM:708ae613bd9b219428a3fb5d"
] | [
"PMID:34112559",
"PMCID:PMC9264795",
"PMCID:PMC9513735"
] | [
"SPAN:e3a06d1caa4bad858a61ecac",
"SPAN:6bce490da9af6629c76192a2",
"SPAN:8b24eb48a5c9dd11defb01ae"
] | [
"ASC2:3b4ebfb0e0b29ade20247320",
"ASC2:537ac47ab1d7dd322b7c2614"
] | [
"HYP:DCH:7d71b7c265ef10b522ab8926",
"HYP:DCH:cbbe75b119b5553dcb38c820"
] | {"qa_id":"QA:41d4569af31232fe78e9a4aa","qa_group_id":"QAG:5f590f865610aac435559442","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"MK-1775 in combination with x-rays inhibited the tumor growth of M... |
QA:420f5b5dfef737af4af91dd1 | QAG:ac18abacf9748761948787ad | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "5 A and B), while exogenous ATF3 expression led to higher levels of LC3-II expression and LC3 puncta accumulation ( Fig. 5 C and D), which could be attenuated by CA-AKT ( Fig. 5 E and F)"? Return the original wording with paper, Claim, and Evidence Span references.
In... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a08207154579a1c48ecf99ae","quotes":["ECON failed to induce elevation of LC3-II levels and LC3 puncta accumulation... | [
"CLM:a08207154579a1c48ecf99ae",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:36af4a6ad40aabad401758a1"
] | [] | [] | {"qa_id":"QA:420f5b5dfef737af4af91dd1","qa_group_id":"QAG:ac18abacf9748761948787ad","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"5 A and B), while exogenous ATF3 expression led to higher levels o... |
QA:42497dab6568855b965ac915 | QAG:ae8e01ca086250738306b2ea | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "PDAC cells overexpressing ISCA1 or control vector received CQ followed by immunoblotting for the indicated proteins in ( D ) and ( E ) followed by analyzing their relative cell proliferation ( F ; combined data of n = 5 experiments)"? Return the original wording with p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e0d6e1d5288015b1dd0283a1","quotes":["PDAC cells overexpressing ISCA1 or control vector were treated with CQ follo... | [
"CLM:e0d6e1d5288015b1dd0283a1",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10115412"
] | [
"SPAN:d77ca570cb04ca64985a6be2"
] | [] | [] | {"qa_id":"QA:42497dab6568855b965ac915","qa_group_id":"QAG:ae8e01ca086250738306b2ea","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"PDAC cells overexpressing ISCA1 or control vector received CQ foll... |
QA:42c504ce57d5f760d5b0d051 | QAG:396c3c48cae3b62ffaff9435 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "35 Our bioinformatics data revealed that the high expression of NMU in pancreatic cancer tissues was associated with poor survival and primary clinical features of pancreatic cancer"? Return the original wording with paper, Claim, and Evidence Span references.
Integra... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7a39d3d7c74b80e294eeefbf","quotes":["35 Our bioinformatics data revealed that the high expression of NMU in pancr... | [
"CLM:7a39d3d7c74b80e294eeefbf",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10859610"
] | [
"SPAN:ff8e70aa1f856c53b8e96192"
] | [] | [] | {"qa_id":"QA:42c504ce57d5f760d5b0d051","qa_group_id":"QAG:396c3c48cae3b62ffaff9435","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"35 Our bioinformatics data revealed that the high expression of NM... |
QA:45b01afdb892682a1d30b4e0 | QAG:86a48a022e6a4020a58fbfe2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "To support our hypothesis that miR-198 precipitates PDAC cell sensitization to gemcitabine treatment through downregulation of VCP, we determined the levels of miR-198 and VCP expression in the treated and untreated xenograft tumor tissue and found that when miR-198 le... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:608d5c31c9ffa78279d0b481","quotes":["To support our hypothesis that miR-198 precipitates PDAC cell sensitization ... | [
"CLM:608d5c31c9ffa78279d0b481",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:443847bed3c1b97c6714839a"
] | [] | [] | {"qa_id":"QA:45b01afdb892682a1d30b4e0","qa_group_id":"QAG:86a48a022e6a4020a58fbfe2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"To support our hypothesis that miR-198 precipitates PDAC cell sens... |
QA:4744abc2327661000d5c1041 | QAG:f8de3ac5a51c26e467986cf7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "however, there are certain instances where the involvement of a specific mechanism that led to the induction of apoptosis has also been proposed 14 , 15 , 50"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requireme... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4aea7aa963155e2ddc76ed54","quotes":["This antitumor effect of ECON against PDAC is in line with previous studies ... | [
"CLM:4aea7aa963155e2ddc76ed54",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:d7dc7e0f74d2688c2f4cc177"
] | [] | [] | {"qa_id":"QA:4744abc2327661000d5c1041","qa_group_id":"QAG:f8de3ac5a51c26e467986cf7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"however, there are certain instances where the involvement of a sp... |
QA:48d3f442f41b3a58651d6ab3 | QAG:c4c3b351ef9b0e143be04b2e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "To further support our hypothesis that miR-198 precipitates PDAC cell sensitization to gemcitabine treatment through downregulation of VCP, we determined the levels of miR-198 and VCP expression in treated and untreated tumor tissues and found that when miR-198 levels ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:32a364aa0c7c7fedd4e9ead0","quotes":["To further support our hypothesis that miR-198 precipitates PDAC cell sensit... | [
"CLM:32a364aa0c7c7fedd4e9ead0",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:d78f120297b13b5efe737061"
] | [] | [] | {"qa_id":"QA:48d3f442f41b3a58651d6ab3","qa_group_id":"QAG:c4c3b351ef9b0e143be04b2e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"To further support our hypothesis that miR-198 precipitates PDAC c... |
QA:4a50a7216b9d2ce7d3df6295 | QAG:e9462ad799edf771aebe5642 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We for the first time showed increased PYGL protein expression in PDAC tissues, which was associated with tumor size, vascular invasion, and TNM stages"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5e41979ac31fe0a90bb804a4","quotes":["We for the first time showed increased PYGL protein expression in PDAC tissu... | [
"CLM:5e41979ac31fe0a90bb804a4",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:3eb15ea7fd4a219efed73b3a"
] | [] | [] | {"qa_id":"QA:4a50a7216b9d2ce7d3df6295","qa_group_id":"QAG:e9462ad799edf771aebe5642","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We for the first time showed increased PYGL protein expression in ... |
QA:4ba8444cea84571550d8313b | QAG:0f1701f6dd8cf589c36332de | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "S7A–S7G ), we assumed that ATF3 might elicit ECON promoted autophagy by downregulating the ID-1-mediated AKT pathway"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9605ca7548acd6fa8199d2e3","quotes":["Since the engagement of AT... | [
"CLM:9605ca7548acd6fa8199d2e3",
"CLM:00354d8cbec4dead29bb8637",
"CLM:0a01e893027b3e621e4f91bf",
"CLM:2e46de0c7b80a9d5c0006a8d",
"CLM:d4223c11dfe7292af121c738",
"CLM:0ca7df168592a8fb98ef0558"
] | [
"PMCID:PMC9293665",
"PMCID:PMC10621596",
"PMCID:PMC8901637",
"PMCID:PMC8903155"
] | [
"SPAN:b93263c9d29550804fe8ccdf",
"SPAN:5b3e8374bba7228f0ad6e1d2",
"SPAN:c12b2be3f0cefe5d09c80a1c",
"SPAN:227b3150422a18a62f133272",
"SPAN:343f79bdf02724fdffd69202",
"SPAN:1fb9e0dfea1cfc926ba3ed6e"
] | [
"ASC2:588d31a27f0a0a23d42677f2",
"ASC2:d0c978b4df5e00d9806bc2d9",
"ASC2:aa5fbb697e2c78b5a8271560"
] | [
"HYP:DCH:2df743001d8c29a67d871874",
"HYP:DCH:ef8ea77fa4219ff5e868dfbb"
] | {"qa_id":"QA:4ba8444cea84571550d8313b","qa_group_id":"QAG:0f1701f6dd8cf589c36332de","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"S7A–S7G ), we assumed that ATF3 might elicit ECON promoted autopha... |
QA:4e3fd62e4e483df1d8e255eb | QAG:f98ece390393315b62a7a2b9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These considerations are further strengthened by our analysis of public databases, showing increased expression of glycolytic enzymes in PDAC patients compared with the normal pancreatic counterpart"? Return the original wording with paper, Claim, and Evidence Span ref... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9b6ca3d863bc560098b5ce02","quotes":["These considerations are further strengthened by our analysis of public data... | [
"CLM:9b6ca3d863bc560098b5ce02",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:e80637eedf4eef087cc5213e"
] | [] | [] | {"qa_id":"QA:4e3fd62e4e483df1d8e255eb","qa_group_id":"QAG:f98ece390393315b62a7a2b9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These considerations are further strengthened by our analysis of p... |
QA:4e40b7651e42a61cd44c1650 | QAG:b80e849105432398d76c0a6f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "( F ) Non-PDAC cancer cells received CQ or cotreated with CQ and FAC and analyzed for the indicated proteins"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with pap... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:13e0fc49df43845a164b6cd9","quotes":["Fig. 7. LIP in PDAC is regulated by autophagy level. ( A ) Heatmap showing t... | [
"CLM:13e0fc49df43845a164b6cd9",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10115412"
] | [
"SPAN:3ca8f5c2d49f048ba058c4eb"
] | [] | [] | {"qa_id":"QA:4e40b7651e42a61cd44c1650","qa_group_id":"QAG:b80e849105432398d76c0a6f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"( F ) Non-PDAC cancer cells received CQ or cotreated with CQ and F... |
QA:4ebd4cb8aeaae7ecd15115ec | QAG:0117e5e9554c3b69c8b05618 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These considerations constitute the rational bases to support the concept that the poor prognosis of PDAC patients might be largely improved after employing targeted therapies affecting energy metabolism"? Return the original wording with paper, Claim, and Evidence Spa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2b4878d5fa259e05f2ffc8c3","quotes":["These considerations constitute the rational bases to support the concept th... | [
"CLM:2b4878d5fa259e05f2ffc8c3",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:c098b0a0a3542f8b093bd94a"
] | [] | [] | {"qa_id":"QA:4ebd4cb8aeaae7ecd15115ec","qa_group_id":"QAG:0117e5e9554c3b69c8b05618","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These considerations constitute the rational bases to support the ... |
QA:4f2db346ac4f557c7cb57016 | QAG:9e6c29cb73074b067f3e6cd6 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "1 High expression of CRABP-II was associated with poor prognostics and drug resistance in human PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Clai... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:45b407179ea096c4c67a8445","quotes":["Fig. 1 High expression of CRABP-II is associated with poor prognostics and d... | [
"CLM:45b407179ea096c4c67a8445",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:ee6ab223b303bdfea11c1d05"
] | [] | [] | {"qa_id":"QA:4f2db346ac4f557c7cb57016","qa_group_id":"QAG:9e6c29cb73074b067f3e6cd6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"1 High expression of CRABP-II was associated with poor prognostics... |
QA:509788b0e968f2855a0b9ee2 | QAG:8a567a69e4a016be13c5a25c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "SCD high CAFs also improved the viability of SW1990, a SCD low pancreatic cancer cell line in zPDX models treated by GEM, DDP, and PTX ( Figure 4 C)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: retu... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4174772a69d0da5a53ebcefa","quotes":["Compared with SCD low CAFs, SCD high CAFs significantly improved the viabili... | [
"CLM:4174772a69d0da5a53ebcefa",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9794976"
] | [
"SPAN:20d91e9b74e366a2745a0a18"
] | [] | [] | {"qa_id":"QA:509788b0e968f2855a0b9ee2","qa_group_id":"QAG:8a567a69e4a016be13c5a25c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"SCD high CAFs also improved the viability of SW1990, a SCD low pan... |
QA:5143249860c2d5b8adf107f8 | QAG:2597906ddd4737536ca88892 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Inconsistent with these observations, CP-320626 decreased the basal levels of ECAR in Patu8988 and PANC-1 cells ( Figure S6 ), possibly due to the different PYGL expression levels among the four PDAC cells"? Return the original wording with paper, Claim, and Evidence S... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:21d9c1ec2f397dc4474aca45","quotes":["Inconsistent with these observations, CP-320626 significantly attenuated the... | [
"CLM:21d9c1ec2f397dc4474aca45",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:3c0c216f282b2d4b7ffa77f6"
] | [] | [] | {"qa_id":"QA:5143249860c2d5b8adf107f8","qa_group_id":"QAG:2597906ddd4737536ca88892","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Inconsistent with these observations, CP-320626 decreased the basa... |
QA:51af6b18a162a56ec0cdcf50 | QAG:a4884778b2ee74008c591aec | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Although we do not know how dietary fat factors modulate the systemic availability of lipids that are available for use by cancer cells within a tumor, it is interesting to note that low-fat dietary intervention was associated with reduced pancreatic cancer incidence i... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b60b3b22b2f46ed2bdb6ee22","quotes":["Although we do not know how dietary fat factors modulate the systemic availa... | [
"CLM:b60b3b22b2f46ed2bdb6ee22",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8742413"
] | [
"SPAN:7baf914c90e85ff18d381e32"
] | [] | [] | {"qa_id":"QA:51af6b18a162a56ec0cdcf50","qa_group_id":"QAG:a4884778b2ee74008c591aec","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Although we do not know how dietary fat factors modulate the syste... |
QA:51bd42121924f99c7ffd8383 | QAG:dedaa9f5d0f5c11f7fc1958c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Since cancer cells display increased uptake of glucose and aerobic glycolysis (the Warburg effect) for their growth requirements, we analysed L-lactate secretion in PDAC cell medium after 48 h treatment with the GAPDH inhibitors AXP-3009, AXP-3018, and AXP-3019. In lin... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3890ce69ef274f80f94d9d78","quotes":["Since cancer cells display increased uptake of glucose and aerobic glycolysi... | [
"CLM:3890ce69ef274f80f94d9d78",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:4916aeeda4838c157c299bbb"
] | [] | [] | {"qa_id":"QA:51bd42121924f99c7ffd8383","qa_group_id":"QAG:dedaa9f5d0f5c11f7fc1958c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Since cancer cells display increased uptake of glucose and aerobic... |
QA:51da218c152848ba78f9608e | QAG:74ba9d8769d497c26d943d95 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "To explore the underlying mechanism of the strong OBP-702 promoted ICD, we analyzed the expression of p53, adenoviral E1A, cleaved PARP (an apoptosis marker), and p62 (an autophagy marker) proteins in p53-intact and p53-mutant human PDAC cells after viral infection"? R... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5eb971576b8d5d1a546db2d7","quotes":["To explore the underlying mechanism of the strong OBP-702-induced ICD, we an... | [
"CLM:5eb971576b8d5d1a546db2d7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:3e32522136b8ecc3d07e083d"
] | [] | [] | {"qa_id":"QA:51da218c152848ba78f9608e","qa_group_id":"QAG:74ba9d8769d497c26d943d95","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"To explore the underlying mechanism of the strong OBP-702 promoted... |
QA:5750693165bac99303c78301 | QAG:f11b38e7dbf92303cc46b2c8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "A phenomenon contributing to therapeutic resistance and dismal prognosis is a unique characteristic of PDAC called desmoplasia, which results in decreased availability of oxygen and nutrients to the cancer"? Return the original wording with paper, Claim, and Evidence S... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ab59120d186bdabbe5a0dce0","quotes":["A phenomenon contributing to therapeutic resistance and dismal prognosis is ... | [
"CLM:ab59120d186bdabbe5a0dce0",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9872233"
] | [
"SPAN:83a126401da0cb498d64dd26"
] | [] | [] | {"qa_id":"QA:5750693165bac99303c78301","qa_group_id":"QAG:f11b38e7dbf92303cc46b2c8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"A phenomenon contributing to therapeutic resistance and dismal pro... |
QA:5768e7298b1bd07614d8a6ec | QAG:39c63391c9db641032832f1f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Results Gemcitabine plus cisplatin increased cell death and induced ferroptosis in PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Eviden... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:352681a21b137f312cb5eca5","quotes":["Results Gemcitabine plus cisplatin enhanced cell de... | [
"CLM:352681a21b137f312cb5eca5",
"CLM:053ffd7bb6e6ca17b0bc3071",
"CLM:121de99ea16e4cdf37c555c8"
] | [
"PMCID:PMC12974020",
"PMCID:PMC10457905"
] | [
"SPAN:fce0baa15ed67f3abedb3135",
"SPAN:19b2aef33c0210b32f779897"
] | [
"ASC2:b37aa3b6fdf5a1677c560984"
] | [] | {"qa_id":"QA:5768e7298b1bd07614d8a6ec","qa_group_id":"QAG:39c63391c9db641032832f1f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Results Gemcitabine plus cisplatin increased cell death and induce... |
QA:577e4c1ca95d4f04f75b6dac | QAG:2eb0cc9d8cfde67ba79ecaaa | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "All pancreatic cancer-derived cell lines were included for analysis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6799103e1b65b7d7ae1f2112","quotes":["All pancreatic cancer-derived cell lines were included for analysis."],"cita... | [
"CLM:6799103e1b65b7d7ae1f2112",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10010283"
] | [
"SPAN:c58c27a16163663efece8058"
] | [] | [] | {"qa_id":"QA:577e4c1ca95d4f04f75b6dac","qa_group_id":"QAG:2eb0cc9d8cfde67ba79ecaaa","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"All pancreatic cancer-derived cell lines were included for analysi... |
QA:5868fdc5b5a5d9da6611b160 | QAG:9b7e94563e8bbec64da3443d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Furthermore, NMU expression was associated with the pathological stage and grade of pancreatic cancer, in patients (Figure 1F,G )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact suppor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:23dc33705d7643ebe5efac7a","quotes":["Furthermore, NMU expression was associated with the pathological stage and g... | [
"CLM:23dc33705d7643ebe5efac7a",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10859610"
] | [
"SPAN:26ead3c5031108a8765d47d8"
] | [] | [] | {"qa_id":"QA:5868fdc5b5a5d9da6611b160","qa_group_id":"QAG:9b7e94563e8bbec64da3443d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Furthermore, NMU expression was associated with the pathological s... |
QA:59d53dd8570178c681f50bf5 | QAG:2c7a539ebb739fa482a24a24 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "GPR55 overexpression and activation was associated with increased proliferation and aggressiveness of PDAC cell lines and tumors"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact support... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0e07f320dd8abc029bcb0175","quotes":["GPR55 overexpression and activation are associated with increased proliferat... | [
"CLM:0e07f320dd8abc029bcb0175",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8901637"
] | [
"SPAN:26b25da25b96c7bf0308c0b6"
] | [] | [] | {"qa_id":"QA:59d53dd8570178c681f50bf5","qa_group_id":"QAG:2c7a539ebb739fa482a24a24","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"GPR55 overexpression and activation was associated with increased ... |
QA:59fa399a4f30899846ff57ac | QAG:ff59e63a6d7e7f5ec11564e3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Iron efflux from the CAFs is then increased via up-regulation of the iron efflux protein FPN, leading to the restoration of the LIP in PDAC cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:611357bed549bf63067c176b","quotes":["Iron efflux from the CAFs is then increased via up-regulation of the iron ef... | [
"CLM:611357bed549bf63067c176b",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC10115412"
] | [
"SPAN:d323b18f4940b2df9cae1aa6"
] | [] | [] | {"qa_id":"QA:59fa399a4f30899846ff57ac","qa_group_id":"QAG:ff59e63a6d7e7f5ec11564e3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Iron efflux from the CAFs is then increased via up-regulation of t... |
QA:5a68e2af66c3a3a3874086a5 | QAG:c3aa7fffafb7657ea402e0af | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We found that inhibition of autophagy increased the accumulation of lipids in LDs, suggesting that autophagy acts to maintain a high LD turnover in pancreatic cancer cells under basal conditions (Fig. 3 A)"? Return the original wording with paper, Claim, and Evidence S... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4ae010be2d1fc849e4c142ab","quotes":["To assess whether the autophagic flux status impacts LDs turnover in pancrea... | [
"CLM:4ae010be2d1fc849e4c142ab",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8742413"
] | [
"SPAN:1ac0537c7cb0485092e56051"
] | [] | [] | {"qa_id":"QA:5a68e2af66c3a3a3874086a5","qa_group_id":"QAG:c3aa7fffafb7657ea402e0af","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We found that inhibition of autophagy increased the accumulation o... |
QA:5a97bc9a63d78f184f99624f | QAG:79f9d63a4cf3885de9c05abe | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Further, we found that increased lipid raft cholesterol content in PDAC cells is associated with activated AKT survival signaling and PDAC chemo-resistance, as depletion of CRABP-II not only decreased lipid raft cholesterol level but also inhibited AKT activation and i... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0ca7df168592a8fb98ef0558","quotes":["F... | [
"CLM:0ca7df168592a8fb98ef0558",
"CLM:03219ae941a2b333b95944b3",
"CLM:2e46de0c7b80a9d5c0006a8d",
"CLM:0a01e893027b3e621e4f91bf"
] | [
"PMCID:PMC8903155",
"PMCID:PMC9293665",
"PMCID:PMC10621596"
] | [
"SPAN:1fb9e0dfea1cfc926ba3ed6e",
"SPAN:5b3e8374bba7228f0ad6e1d2",
"SPAN:c12b2be3f0cefe5d09c80a1c"
] | [
"ASC2:aa5fbb697e2c78b5a8271560",
"ASC2:3af5380ee3384aa92e64d1b9"
] | [
"HYP:DCH:bd0e1f37b0dd47dfe0e790f8",
"HYP:DCH:d83fa33b14337d76408fd1e4",
"HYP:DCH:e66492052c8e438c6245195c"
] | {"qa_id":"QA:5a97bc9a63d78f184f99624f","qa_group_id":"QAG:79f9d63a4cf3885de9c05abe","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Further, we found that increased lipid raft cholesterol content in... |
QA:5bb5ddd43420eb8f364841ba | QAG:8f69d4aa34846daa76cdcbd8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Inhibition of glucose metabolism with low-dose 2-deoxyglucose in combination with a MEK inhibitor promoted apoptosis in Kras G12D -driven PDAC cells in vitro"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requireme... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5cd9b9b1f87bdb692c236f9e","quotes":["Inhibition of glucose metabolism with low-dose 2-de... | [
"CLM:5cd9b9b1f87bdb692c236f9e",
"CLM:03219ae941a2b333b95944b3",
"CLM:47e9104cdc30af1ee58d8e0f"
] | [
"PMCID:PMC8338909",
"PMCID:PMC10664664"
] | [
"SPAN:821fe3257a23ada4621d9aa9",
"SPAN:96a96f6c9d4bad191c7c29e2"
] | [
"ASC2:003d65fc9d6e8cf84f1e76f7"
] | [] | {"qa_id":"QA:5bb5ddd43420eb8f364841ba","qa_group_id":"QAG:8f69d4aa34846daa76cdcbd8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Inhibition of glucose metabolism with low-dose 2-deoxyglucose in c... |
QA:5be63ef19dc9baf209a0a911 | QAG:f44c12edb2973f339ecba49f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "5 μM Y27632 (Selleckchem) and 10% growth factor decreased Matrigel (Corning) onto 96-well clear flat bottom plates (Corning) coated with poly(2-hydroxyethyl methacrylate) (Sigma-Aldrich)"? Return the original wording with paper, Claim, and Evidence Span references.
In... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a8d40bedc863eb1eed5e20a3","quotes":["PDAC organoids were dissociated and 3 × 10 3 cells were seeded in 150 μl of ... | [
"CLM:a8d40bedc863eb1eed5e20a3",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8665414"
] | [
"SPAN:0c57d1c9c5ccf8b4a2529d01"
] | [] | [] | {"qa_id":"QA:5be63ef19dc9baf209a0a911","qa_group_id":"QAG:f44c12edb2973f339ecba49f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"5 μM Y27632 (Selleckchem) and 10% growth factor decreased Matrigel... |
QA:5c211fc3515dbb1b22ea64a9 | QAG:2dcae9403450212aeab42f88 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 5 OBP-702 induces immunogenic cell death in murine PDAC cells (A and B) Murine PAN02 cells received OBP-301 or OBP-702 at the indicated MOI for 48 h"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirement... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:93a275dc2034042fd129d59b","quotes":["Figure 5 OBP-702 induces immunogenic cell death in murine PDAC cells (A and ... | [
"CLM:93a275dc2034042fd129d59b",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:2ee0b9227fbfe261c7669b1f"
] | [] | [] | {"qa_id":"QA:5c211fc3515dbb1b22ea64a9","qa_group_id":"QAG:2dcae9403450212aeab42f88","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 5 OBP-702 induces immunogenic cell death in murine PDAC cel... |
QA:5c710139e8fc135db78a514b | QAG:8845f0e4a714c3fbb386cdc0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "13 Perineural invasion is a typical feature of pancreatic cancer and was associated with poor prognosis in PDAC patients"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting pass... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bcd6b6a442b74f3ca1291da7","quotes":["13 Perineural invasion is a typical feature of pancreatic cancer and is asso... | [
"CLM:bcd6b6a442b74f3ca1291da7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10859610"
] | [
"SPAN:a767f49a7f08f17cc0ca40b3"
] | [] | [] | {"qa_id":"QA:5c710139e8fc135db78a514b","qa_group_id":"QAG:8845f0e4a714c3fbb386cdc0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"13 Perineural invasion is a typical feature of pancreatic cancer a... |
QA:5d0918895bf1aa64e55fe518 | QAG:492f4a3e4556b68c7d383a00 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "NURR1 was also overexpressed in grade 2 tumor samples confirming that high levels of NURR1 was associated with the severity of PDAC ( Fig. 1C )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return th... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2832ffae91ad072698c28f5e","quotes":["NURR1 was also overexpressed in grade 2 tumor samples confirming that high l... | [
"CLM:2832ffae91ad072698c28f5e",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:a3e8e4dd853c753e649d9956"
] | [] | [] | {"qa_id":"QA:5d0918895bf1aa64e55fe518","qa_group_id":"QAG:492f4a3e4556b68c7d383a00","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"NURR1 was also overexpressed in grade 2 tumor samples confirming t... |
QA:5da55d57539a11a5bd5e611f | QAG:e529a2d36d413c6e469fbdd2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In contrast, when combined with CQ or bafilomycin A1 (Baf-A1, two late-autophagy inhibitors), the antitumor activity of ECON in PDAC cells was significantly exacerbated due to the substantial accumulation of autophagosomes, as demonstrated by increased LC3-II expressio... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d1af4147909d0ebeedf88a7f","quotes":["In contrast, when combined with CQ or bafilomycin A1 (Baf-A1, two late-autop... | [
"CLM:d1af4147909d0ebeedf88a7f",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:e7f63ddb144ad9de20ab8c83"
] | [] | [] | {"qa_id":"QA:5da55d57539a11a5bd5e611f","qa_group_id":"QAG:e529a2d36d413c6e469fbdd2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In contrast, when combined with CQ or bafilomycin A1 (Baf-A1, two ... |
QA:5dc7beb469d27e04d3e97442 | QAG:ddff3c77162ac20a3dcc6ec3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "DDR1 displays sustained activation upon interaction with collagen and the high expression level of DDR1 was correlated with poor PDAC survival, implying that collagen/DDR1 mediated signaling would play an important role in cancer progression"? Return the original wordi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31cea731c6f7bfd0e08516d4","quotes":["DDR1 displays sustained activation upon interaction with collagen and the hi... | [
"CLM:31cea731c6f7bfd0e08516d4",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10710504"
] | [
"SPAN:1fe7f0f1563adb91988541a1"
] | [] | [] | {"qa_id":"QA:5dc7beb469d27e04d3e97442","qa_group_id":"QAG:ddff3c77162ac20a3dcc6ec3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"DDR1 displays sustained activation upon interaction with collagen ... |
QA:5dc9ede78c8025e6e5d4e0fc | QAG:45960613dcb4198fed1ccb89 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Overall, the above results indicate that high PYGL expression is correlated with more aggressive behaviors in PDAC patients and predicted a poor prognosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:00354d8cbec4dead29bb8637","quotes":["Overall, the above results indicate that high PYGL expression is correlated ... | [
"CLM:00354d8cbec4dead29bb8637",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:087a8d48170fd8492a9a5dcd"
] | [] | [] | {"qa_id":"QA:5dc9ede78c8025e6e5d4e0fc","qa_group_id":"QAG:45960613dcb4198fed1ccb89","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Overall, the above results indicate that high PYGL expression is c... |
QA:5e2072ffb8ac69be4b390c7d | QAG:b319c1c9ff3dc0818ed0f8b9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "To further explore the prognostic value of ATF3 in PDAC, we analyzed the correlation between ATF3 expression and patient survival in TCGA and Oncomine datasets and found that a high level of ATF3 was correlated with improved cumulative survival ( Fig. S5I and S5J )"? R... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bcfceba085672618ec939d0b","quotes":["To further explore the prognostic value of ATF3 in PDAC, we analyzed the cor... | [
"CLM:bcfceba085672618ec939d0b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:ddd822687aa8427e847d6535"
] | [] | [] | {"qa_id":"QA:5e2072ffb8ac69be4b390c7d","qa_group_id":"QAG:b319c1c9ff3dc0818ed0f8b9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"To further explore the prognostic value of ATF3 in PDAC, we analyz... |
QA:5f112ff53c4fbb30dc209b85 | QAG:a49e24cc6ee03012e57dd0a9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "As expected, PDAC cells exhibited increased nuclear expression of ATF3 in response to ECON ( Fig. 5 G), which was consistent with the results from immunofluorescence and IHC analysis ( Fig. 5 H and I)"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:15b33ca80f01ad40b4def86b","quotes":["As expected, PDAC cells exhibited increased nuclear expression of ATF3 in re... | [
"CLM:15b33ca80f01ad40b4def86b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:43d63101e8b09d5d71aac02b"
] | [] | [] | {"qa_id":"QA:5f112ff53c4fbb30dc209b85","qa_group_id":"QAG:a49e24cc6ee03012e57dd0a9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"As expected, PDAC cells exhibited increased nuclear expression of ... |
QA:5fc7ec03ded0314994dac213 | QAG:bcd0eb1e36a4d976a26ca566 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Taken together, these observations demonstrated that the highly expressed CRABP-II promotes PDAC drug-resistance through stabilizing SREBP-1c mRNA and the up-regulation of cholesterol metabolic genes, which led to the elevation of the lipid raft cholesterol accumulatio... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bc9e733412fea71f1c0b3786","quotes":["Taken together, these observations demonstrated that the highly expressed CR... | [
"CLM:bc9e733412fea71f1c0b3786",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:1f79c66daca56e39dfe4f6ad"
] | [] | [] | {"qa_id":"QA:5fc7ec03ded0314994dac213","qa_group_id":"QAG:bcd0eb1e36a4d976a26ca566","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Taken together, these observations demonstrated that the highly ex... |
QA:61387315e5a34ccef3f48866 | QAG:a8066922d23c7da4ba3ba7cf | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor prognosis and chemotherapy with gemcitabine has limited effects and was associated with development of drug resistance"? Return the original wording with paper, Claim, and Evidence... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a3d460056003495f262aea02","quotes":["Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive canc... | [
"CLM:a3d460056003495f262aea02",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:6aa7c666086220204b19d2c3"
] | [] | [] | {"qa_id":"QA:61387315e5a34ccef3f48866","qa_group_id":"QAG:a8066922d23c7da4ba3ba7cf","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggre... |
QA:63d45a1bcc5dae2fb9509da8 | QAG:8d99965486eddcf3e9d74c05 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These findings showed that increased NMU expression is an early and persistent event in pancreatic tumorigenesis that can be regarded as a potential marker for the early diagnosis of pancreatic cancer"? Return the original wording with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d427252ad9489238a7dc4e56","quotes":["These findings showed that increased NMU expression is an early and persiste... | [
"CLM:d427252ad9489238a7dc4e56",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10859610"
] | [
"SPAN:c79f37d24d590e80e896b46b"
] | [] | [] | {"qa_id":"QA:63d45a1bcc5dae2fb9509da8","qa_group_id":"QAG:8d99965486eddcf3e9d74c05","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These findings showed that increased NMU expression is an early an... |
QA:64feab8ce52bd5bbbcbbb9ad | QAG:20d02b664b21e8ef98aa0581 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "When combined with FIRINOX, ATI-450 eliminated most PDAC foci and marked prolonged mouse survival without causing additional toxicity"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact su... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9584602c0e653be945f0b9df","quotes":["When combined with FIRINOX, ATI-450 eliminated most PDAC foci and marked pro... | [
"CLM:9584602c0e653be945f0b9df",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9475471"
] | [
"SPAN:c9456987d542d0711eed1c7a"
] | [] | [] | {"qa_id":"QA:64feab8ce52bd5bbbcbbb9ad","qa_group_id":"QAG:20d02b664b21e8ef98aa0581","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"When combined with FIRINOX, ATI-450 eliminated most PDAC foci and ... |
QA:65c79734d4e2ee871ba70fae | QAG:5098056ac4d39e0270590529 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "It is worth noting that OBP-702 efficiently promoted ICD in murine PAN02 cells in the present study, despite low CAR expression ( Figures 5 and S11 )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: ret... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5666aa90b75d9517db663110","quotes":["It is worth noting that OBP-702 efficiently induced ICD in murine PAN02 cell... | [
"CLM:5666aa90b75d9517db663110",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:35a3cf9efb8e750d7f028780",
"SPAN:efcca84b267fb45fdfe919bd"
] | [] | [] | {"qa_id":"QA:65c79734d4e2ee871ba70fae","qa_group_id":"QAG:5098056ac4d39e0270590529","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"It is worth noting that OBP-702 efficiently promoted ICD in murine... |
QA:678669ff4f718cb5c2528046 | QAG:7523d55e8f0519afbe08c2c0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "PDAC cells treated with CM from IL-17RB OE PSCs showed a trend towards increased OCR compared with control CM and a significant increase of the OCR compared with naive tumor cells ( Figure 5 A)"? Return the original wording with paper, Claim, and Evidence Span referenc... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fb7a8e20fcfbedcd9c648208","quotes":["PDAC cells treated with CM from IL-17RB OE PSCs showed a trend towards incre... | [
"CLM:fb7a8e20fcfbedcd9c648208",
"CLM:0c27354d7b6b89a38805175d"
] | [
"PMCID:PMC8611647"
] | [
"SPAN:04eeaf1978df28a944692bb5"
] | [] | [] | {"qa_id":"QA:678669ff4f718cb5c2528046","qa_group_id":"QAG:7523d55e8f0519afbe08c2c0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"PDAC cells treated with CM from IL-17RB OE PSCs showed a trend tow... |
QA:68145e4ba583f505bc072109 | QAG:b463eedee54d1d1405fcb9dd | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Further, we found that increased lipid raft cholesterol content in PDAC cells is associated with activated AKT survival signaling and PDAC chemo-resistance, as depletion of CRABP-II not only decreased lipid raft cholesterol level but also inhibited AKT activation and i... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:81a58aa28656b0d787a26116","quotes":["Further, we found that increased lipid raft cholesterol content in PDAC cell... | [
"CLM:81a58aa28656b0d787a26116",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:1fb9e0dfea1cfc926ba3ed6e"
] | [] | [] | {"qa_id":"QA:68145e4ba583f505bc072109","qa_group_id":"QAG:b463eedee54d1d1405fcb9dd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Further, we found that increased lipid raft cholesterol content in... |
QA:690be24b213b50530d8d13c3 | QAG:b050ddc06891f2e65b625420 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We then aims to evaluate whether suppression of ACSL3 affects human pancreatic cancer cell proliferation"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:df16d3e0f69ddf929d4b33ed","quotes":["We then aimed to evaluate whether suppression of ACSL3 affects human pancrea... | [
"CLM:df16d3e0f69ddf929d4b33ed",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8742413"
] | [
"SPAN:e6473886cba051f66707ab3a"
] | [] | [] | {"qa_id":"QA:690be24b213b50530d8d13c3","qa_group_id":"QAG:b050ddc06891f2e65b625420","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We then aims to evaluate whether suppression of ACSL3 affects huma... |
QA:6a14e05e0334f95ec5007d1b | QAG:76c79525ac4c83bf2aeee9e0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We have shown therapeutic delivery of miR-198 using LGA-PEI as a delivery system resulted in repression of VCP-associated autophagy and sensitized to gemcitabine treatment, reducing tumor burden and metastatic spread in PDAC mouse models"? Return the original wording w... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d1a9cc9a375a43a23917901e","quotes":["We have shown therapeutic delivery of miR-198 using LGA-PEI as a delivery sy... | [
"CLM:d1a9cc9a375a43a23917901e",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:19b2aef33c0210b32f779897"
] | [] | [] | {"qa_id":"QA:6a14e05e0334f95ec5007d1b","qa_group_id":"QAG:76c79525ac4c83bf2aeee9e0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We have shown therapeutic delivery of miR-198 using LGA-PEI as a d... |
QA:6a568a0c99a4e702ee4b8ff3 | QAG:c4511d2ba8296a258bbee559 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "The p53-mediated induction of apoptosis and autophagy in human and murine PDAC cells observed in the present study was associated with OBP-702-induced release of ATP and HMGB1 ( Figures 4 and 5 )"? Return the original wording with paper, Claim, and Evidence Span refere... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:da857ebd61ccd7fbba85a0b7","quotes":["The p53-mediated induction of apoptosis and autophagy in human and murine PD... | [
"CLM:da857ebd61ccd7fbba85a0b7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:d3e31e6c3e28f670fa506068"
] | [] | [] | {"qa_id":"QA:6a568a0c99a4e702ee4b8ff3","qa_group_id":"QAG:c4511d2ba8296a258bbee559","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"The p53-mediated induction of apoptosis and autophagy in human and... |
QA:6b0191af807bcb46f2f3fad2 | QAG:e5b5ef4a70a3c41b6d778c3e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "( R , S ′)-MNF treatment decreased HIF-1α and c-Myc expression, attenuated glycolysis, shifted fatty acid metabolism towards β-oxidation, and suppressed de novo pyrimidine biosynthesis in PANC-1 tumors"? Return the original wording with paper, Claim, and Evidence Span ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ff2f4c4e6c56be08a0c0530e","quotes":["Transcriptomics and immunoblot analyses indicated the downregulation of gene... | [
"CLM:ff2f4c4e6c56be08a0c0530e",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC8901637"
] | [
"SPAN:81e4e35ceeb1b7a94797d9bb"
] | [] | [] | {"qa_id":"QA:6b0191af807bcb46f2f3fad2","qa_group_id":"QAG:e5b5ef4a70a3c41b6d778c3e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"( R , S ′)-MNF treatment decreased HIF-1α and c-Myc expression, at... |
QA:6b9ac535c096a8b6b4c9f9b6 | QAG:2d715fc2dcb60982bb79d297 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In the past couple of decades, the outcome of PDAC has not been improved substantially with the overall 5-year survival rate remains dismal around 8%"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: ret... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eae1dc8030ad5293003a3d96","quotes":["In the past couple of decades, the outcome of PDAC has not been improved sub... | [
"CLM:eae1dc8030ad5293003a3d96",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:4054cda7dd8ec1ad6d1b369f"
] | [] | [] | {"qa_id":"QA:6b9ac535c096a8b6b4c9f9b6","qa_group_id":"QAG:2d715fc2dcb60982bb79d297","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In the past couple of decades, the outcome of PDAC has not been im... |
QA:6cd783a2204c67608df58657 | QAG:0116bc7f279288e9bcecf7d4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Additional file 4: Figure S4 LPA produced by LIPH promoted PDAC progression through enhancing glycolysis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1ac2cc9cef6480e8d7f06452","quotes":["Scale bar = 100 µm. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001. ... | [
"CLM:1ac2cc9cef6480e8d7f06452",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:887d9767063285b556f46e31"
] | [] | [] | {"qa_id":"QA:6cd783a2204c67608df58657","qa_group_id":"QAG:0116bc7f279288e9bcecf7d4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Additional file 4: Figure S4 LPA produced by LIPH promoted PDAC pr... |
QA:6e1ab67927d171a396cdf7bf | QAG:453364edbdcfdd8dc93410bb | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Hence, early diagnosis and timely treatment was associated with a reduced incidence and mortality of pancreatic cancer"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passag... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e42ce83d61a9c6be1a8269dd","quotes":["Hence, early diagnosis and timely treatment are associated with a reduced in... | [
"CLM:e42ce83d61a9c6be1a8269dd",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:39079d47b93c806d9f7e3f56"
] | [] | [] | {"qa_id":"QA:6e1ab67927d171a396cdf7bf","qa_group_id":"QAG:453364edbdcfdd8dc93410bb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Hence, early diagnosis and timely treatment was associated with a ... |
QA:6e806e87dc76ce06761ced52 | QAG:331c848744dc1d4679655079 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "This study demonstrated that LIPH expression is upregulated and predicted poor overall survival in PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, C... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c77f164a95184ffa71013488","quotes":["This study demonstrated that LIPH expression is upregulated and predicts poo... | [
"CLM:c77f164a95184ffa71013488",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:4d5a2e64cd7ff1c0b769e918"
] | [] | [] | {"qa_id":"QA:6e806e87dc76ce06761ced52","qa_group_id":"QAG:331c848744dc1d4679655079","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"This study demonstrated that LIPH expression is upregulated and pr... |
QA:715c0ca080f9b8b1b995f8d1 | QAG:9073608dac8822ae8fc7ebd4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Obesity, which systematically elevates serum lipid levels was associated with pancreatic cancer with poor prognosis, and the possibility of distant metastasis [ 40 – 42 ]"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provena... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:92aff6cbdb3550acf683f5c2","quotes":["Obesity, which systematically elevates serum lipid levels, is associated wit... | [
"CLM:92aff6cbdb3550acf683f5c2",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:c2402831d9d5906018c78d9e"
] | [] | [] | {"qa_id":"QA:715c0ca080f9b8b1b995f8d1","qa_group_id":"QAG:9073608dac8822ae8fc7ebd4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Obesity, which systematically elevates serum lipid levels was asso... |
QA:71ae3244d41ca2bd018d49e4 | QAG:be248c9ae261f40e2e56e0d7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "At the same time, it also predicted PDAC recurrence"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; assess the embed... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8f3d8d732c675e3d214d30da","quotes":["At the same time, it also predicted PDAC recurrence."],"citations":[{"paper_... | [
"CLM:8f3d8d732c675e3d214d30da",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:fb8450874768d0e4dd229a81"
] | [] | [] | {"qa_id":"QA:71ae3244d41ca2bd018d49e4","qa_group_id":"QAG:be248c9ae261f40e2e56e0d7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"At the same time, it also predicted PDAC recurrence\"? Return the ... |
QA:72b570d9ca67494520591a20 | QAG:cca4587970e9bb161f99d868 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC cells treated with 10 μM AXP-3009 or AXP-3019 for 48 h show enhanced binding with annexin V, indicating increased externalization of phosphatidylserine and apoptotic cell death"? Return the original wordin... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dd6b0cbf4b24d6981e8fead8","quotes":["As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC cells treate... | [
"CLM:dd6b0cbf4b24d6981e8fead8",
"CLM:053ffd7bb6e6ca17b0bc3071"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:1bbea122533245abb7be9427"
] | [] | [] | {"qa_id":"QA:72b570d9ca67494520591a20","qa_group_id":"QAG:cca4587970e9bb161f99d868","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"As shown in Figure 6 a, annexin V/FITC assay revealed that PDAC ce... |
QA:76367786d9f982ca2b7506ae | QAG:0a01192cf97ddca13dd1d694 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Cell viability assays showed that knockdown of SAT1 increased cell survival in PDAC cells treated with gemcitabine and cisplatin (Fig. 4.B)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ex... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:89a0efb2e47a6260bdaf4520","quotes":["Cell viability assays showed that knockdown of\nSAT1 increased cell survival... | [
"CLM:89a0efb2e47a6260bdaf4520",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC12974020"
] | [
"SPAN:5e46add9fa7c06003267b644"
] | [] | [] | {"qa_id":"QA:76367786d9f982ca2b7506ae","qa_group_id":"QAG:0a01192cf97ddca13dd1d694","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Cell viability assays showed that knockdown of SAT1 increased cell... |
QA:76e396d96689532c6b6587b2 | QAG:0392a675ab5183079e22f425 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We initially examined the TCGA database and observed that expression of the orphan nuclear receptor NURR1 was more highly expressed in pancreatic tumors compared with the normal pancreas and patients with pancreatic cancer expressing high levels of NURR1 exhibited decr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2a66ea6a237f2e5323866734","quotes":["We initially examined the TCGA database and observed that expression of the ... | [
"CLM:2a66ea6a237f2e5323866734",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:360e8930a77b21f7632f36c1"
] | [] | [] | {"qa_id":"QA:76e396d96689532c6b6587b2","qa_group_id":"QAG:0392a675ab5183079e22f425","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We initially examined the TCGA database and observed that expressi... |
QA:774562f8962894ea32bc3cfa | QAG:777b61b1fc1728f630fb930e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Thus, we examined whether PYGL expression is promoted in hypoxia in PDAC cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1d62a9f67e3384405583783b","quotes":["Thus, we examined whether PYGL expression is induced in hypoxia in PDAC cell... | [
"CLM:1d62a9f67e3384405583783b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:641cc364669c228b45b7a801"
] | [] | [] | {"qa_id":"QA:774562f8962894ea32bc3cfa","qa_group_id":"QAG:777b61b1fc1728f630fb930e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Thus, we examined whether PYGL expression is promoted in hypoxia i... |
QA:7894d301c2dfc6a70273aa74 | QAG:a7afec65d3db1cecfa793bc8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "reported that the starvation promoted TFEB nuclear translocation in HeLa cells was suppressed by ERK/MAPK2-mediated phosphorylation , which was also observed in PDAC models that inhibition of RAS–RAF–MEK–ERK/MAPK signaling pathway resulted in increased autophagic flux"... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b627cf9fb4b5f3a14befd26a","quotes":["In addition, Settembre et al. reported that the starvation-induced TFEB nucl... | [
"CLM:b627cf9fb4b5f3a14befd26a",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9614569"
] | [
"SPAN:0ee16eccd4a04822f4f809b5"
] | [] | [] | {"qa_id":"QA:7894d301c2dfc6a70273aa74","qa_group_id":"QAG:a7afec65d3db1cecfa793bc8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"reported that the starvation promoted TFEB nuclear translocation i... |
QA:7943e7e95190447ba5b8cb4e | QAG:61c6b28d35468edf6332e0c5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Phospho-Ser784-VCP Drives Resistance of Pancreatic Ductal Adenocarcinoma to Genotoxic Chemotherapies and predicted the Chemo-Sensitizing Effect of VCP Inhibitor"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requir... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8fe3e04ee54af9fd73654c4a","quotes":["2017;55:KV-182. 40. Wang F., Vij K., Li L., Dodhiawala P., Lim K.-H., Shao J... | [
"CLM:8fe3e04ee54af9fd73654c4a",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:cc052006edf461b03a9d0b99"
] | [] | [] | {"qa_id":"QA:7943e7e95190447ba5b8cb4e","qa_group_id":"QAG:61c6b28d35468edf6332e0c5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Phospho-Ser784-VCP Drives Resistance of Pancreatic Ductal Adenocar... |
QA:796f19ce68c58a74e655dd52 | QAG:b5f3411f734f992311b1c61e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 7 GbcxMRS predicted PDAC subtypes and influenced the tumor microenvironment (TME). ( a , b ) The landscape of the proportion of different PDAC subtypes in the high and low gbcxMRS groups in the ( a ) E-MTAB-6134 cohort ( n = 257) and ( b ) ICGC cohort ( n = 56).... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5b01475443c151b3e0dba931","quotes":["Figure 7 GbcxMRS predicted PDAC subtypes and influenced the tumor microenvir... | [
"CLM:5b01475443c151b3e0dba931",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:d9e7d70165b2ce61fe5fa870"
] | [] | [] | {"qa_id":"QA:796f19ce68c58a74e655dd52","qa_group_id":"QAG:b5f3411f734f992311b1c61e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 7 GbcxMRS predicted PDAC subtypes and influenced the tumor ... |
QA:79f0a8c92f168a9cb88eb1e9 | QAG:1b03215aa8a63aeb80d1a327 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "As a result, the accumulation of cholesterol promoted by CRABP-II in lipid rafts increased the AKT survival signaling and reduced gemcitabine mediated PDAC apoptosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:602576768fb75e245331df47","quotes":["As a result, the accumulation of cholesterol promoted by CRABP-II in lipid r... | [
"CLM:602576768fb75e245331df47",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:c2cf2cef84bb05589e01dda6"
] | [] | [] | {"qa_id":"QA:79f0a8c92f168a9cb88eb1e9","qa_group_id":"QAG:1b03215aa8a63aeb80d1a327","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"As a result, the accumulation of cholesterol promoted by CRABP-II ... |
QA:7a13ad0acac4803462cd4635 | QAG:ddc16fc3b43c7ef10d4baa6f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Moreover, OBP-702 decreased the expression of p62 in human PDAC cells to a greater degree than OBP-301 ( Figures 4 A and 4B)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ac0e403ad0e262ebecf9c5ce","quotes":["Moreover, OBP-702 decreased the expression of p62 in human PDAC cells to a g... | [
"CLM:ac0e403ad0e262ebecf9c5ce",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:e8e583d14f80f28b3b0b346b"
] | [] | [] | {"qa_id":"QA:7a13ad0acac4803462cd4635","qa_group_id":"QAG:ddc16fc3b43c7ef10d4baa6f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Moreover, OBP-702 decreased the expression of p62 in human PDAC ce... |
QA:7a6ea678ca6404dee4972e30 | QAG:71da41a30fa41dc98e33db0d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "4 f&4 g), indicating that targeting CRABP-II in PDAC also inhibited cancer cell stemness"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evide... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5cfd2bb5a38f3606e2dad210","quotes":["While control tumors showed robust growth upon re-planting, SNIPER-11 treate... | [
"CLM:5cfd2bb5a38f3606e2dad210",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:b08ddcf25edf83bc0b5028f6"
] | [] | [] | {"qa_id":"QA:7a6ea678ca6404dee4972e30","qa_group_id":"QAG:71da41a30fa41dc98e33db0d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"4 f&4 g), indicating that targeting CRABP-II in PDAC also inhibite... |
QA:7a795adc59f92bb742e43742 | QAG:b33cae0008c92b10df895893 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "org/ , accessed on 22 March 2021) was used as the primary validation cohort, and only patients whose pathological type was PDAC were included ( n = 66)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: r... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c5c223b01cd4a9151c2deb4b","quotes":["PACA-AU from the International Cancer Genome Consortium (ICGC, https://dcc.i... | [
"CLM:c5c223b01cd4a9151c2deb4b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:3d6952f07a4895c0008e9946"
] | [] | [] | {"qa_id":"QA:7a795adc59f92bb742e43742","qa_group_id":"QAG:b33cae0008c92b10df895893","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"org/ , accessed on 22 March 2021) was used as the primary validati... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.