qa_id stringlengths 27 27 | qa_group_id stringlengths 28 32 | qa_family stringclasses 3
values | subtask_type stringclasses 7
values | qa_subtype stringclasses 3
values | cluster_id stringclasses 42
values | language stringclasses 1
value | split stringclasses 1
value | question stringlengths 148 1.41k | answer stringlengths 718 10.8k | claim_ids listlengths 0 8 | paper_ids listlengths 1 5 | evidence_span_ids listlengths 0 7 | association_ids listlengths 0 4 | hypothesis_ids listlengths 0 4 | record_json stringlengths 4.37k 33.7k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QA:d285f97c900c3028e2861483 | QAG:89ac0aa334c9a2fb41bb3e76 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Decreased expression of TRIM11 in PDAC patients was associated with decreased UBE2N and increased TAX1BP1 expression"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2eaec7509a7f3b9d9e518c46","quotes":["Decreased expression of TRIM11 in PDAC patients is associated with decreased... | [
"CLM:2eaec7509a7f3b9d9e518c46",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMID:33629745"
] | [
"SPAN:7bb45d92e7d6a916a5466c24"
] | [] | [] | {"qa_id":"QA:d285f97c900c3028e2861483","qa_group_id":"QAG:89ac0aa334c9a2fb41bb3e76","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Decreased expression of TRIM11 in PDAC patients was associated wit... |
QA:d30ed951d162ffcc9df8b992 | QAG:a14a6ddfb932b1fcb536e339 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In line with our data on GAPDH activity and cellular-proliferation inhibition, Figure 4 a shows that AXP-3009 and even more AXP-3019 treatments strongly decreased L-lactate secretion in PANC-1 and MIA PaCa-2 cell lines compared to untreated cells, while AXP-3018 did no... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7c417f0d3183e998e0530ed5","quotes":["Since cancer cells display increased uptake of glucose and aerobic glycolysi... | [
"CLM:7c417f0d3183e998e0530ed5",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:4916aeeda4838c157c299bbb"
] | [] | [] | {"qa_id":"QA:d30ed951d162ffcc9df8b992","qa_group_id":"QAG:a14a6ddfb932b1fcb536e339","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In line with our data on GAPDH activity and cellular-proliferation... |
QA:d327d7cee92109a2158a9e55 | QAG:c5e0288d7f0dd387fdfed7e4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "1 PAL/HCQ free drug combination led to synergized anti-proliferative effect in PDAC cell lines. a BrdU proliferation assay was performed on PDAC cells treated by free PAL/HCQ mixtures at various combination molar ratios"? Return the original wording with paper, Claim, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dfca7ccc3eeadea4d099dc5b","quotes":["Fig. 1 PAL/HCQ free drug combination led to synergized anti-proliferative ef... | [
"CLM:dfca7ccc3eeadea4d099dc5b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC7447818"
] | [
"SPAN:02b8944da95e3d8d5509f76d"
] | [] | [] | {"qa_id":"QA:d327d7cee92109a2158a9e55","qa_group_id":"QAG:c5e0288d7f0dd387fdfed7e4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"1 PAL/HCQ free drug combination led to synergized anti-proliferati... |
QA:d39dfa63b66a0355e5ec76d5 | QAG:f4e8ad3df0e4a4cc4c7514a2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These observations coupled with the anticarcinogenic effects of C-DIM12 suggest that the effectiveness of therapeutic regimens including gemcitabine for treatment of PDAC can be increased using combination therapies that include a NURR1 antagonist such as C-DIM12"? Ret... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f8e6b6512aa475e83d15efad","quotes":["These observations coupled with the anticarcinogenic effects of C-DIM12 sugg... | [
"CLM:f8e6b6512aa475e83d15efad",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:8acdeb412379e61e6e00556c"
] | [] | [] | {"qa_id":"QA:d39dfa63b66a0355e5ec76d5","qa_group_id":"QAG:f4e8ad3df0e4a4cc4c7514a2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These observations coupled with the anticarcinogenic effects of C-... |
QA:d53792021efa1b250370d0d4 | QAG:94c5b629be54bb940028485e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These and other observations led to an increasing interest in the study and inhibition of GAPDH to achieve a metabolic blockade of cancer cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return th... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:cb7042b9fa80c8f4e9e9e26b","quotes":["These and other observations led to an increasing interest in the study and ... | [
"CLM:cb7042b9fa80c8f4e9e9e26b",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:22778ec50d4881c7204ce457",
"SPAN:630084d681d461b90d30def6"
] | [] | [] | {"qa_id":"QA:d53792021efa1b250370d0d4","qa_group_id":"QAG:94c5b629be54bb940028485e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These and other observations led to an increasing interest in the ... |
QA:d56be4b3ccd252a3d8b64d5a | QAG:ea1a8586353a9634498d322e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "The current study demonstrates that ( R , S ′)-MNF has the potential to provide a unique contribution to the treatment of PDAC, which is under investigation using patient-derived xenograft (PDX) models with ( R , S ′)-MNF administered as a single agent and in combinati... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f21ede48ee9563555376d8a0","quotes":["The current study demonstrates that ( R , S ′)-MNF has the potential to prov... | [
"CLM:f21ede48ee9563555376d8a0",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8901637"
] | [
"SPAN:1d8bc1b6392109672a104750"
] | [] | [] | {"qa_id":"QA:d56be4b3ccd252a3d8b64d5a","qa_group_id":"QAG:ea1a8586353a9634498d322e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"The current study demonstrates that ( R , S ′)-MNF has the potenti... |
QA:d5f3f6ce31354979ee1ac65d | QAG:e539d4984e3433267bc16f1d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "When the tumor volumes achieved ∼100 mm 3 , mice bearing PDAC xenografts were randomly divided into 6 groups and received following treatments, respectively, including i) vehicle; ii) 25 mg/kg ECON; iii) 25 mg/kg CQ; iv) 1 mg/kg trametinib; v) 25 mg/kg ECON + 1 mg/kg t... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5d8754f30ea9c3e3ec384712","quotes":["When the tumor volumes reached ∼100 mm 3 , mice bearing PDAC xenografts were... | [
"CLM:5d8754f30ea9c3e3ec384712",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:2328e80edfe459f0afb10601"
] | [] | [] | {"qa_id":"QA:d5f3f6ce31354979ee1ac65d","qa_group_id":"QAG:e539d4984e3433267bc16f1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"When the tumor volumes achieved ∼100 mm 3 , mice bearing PDAC xeno... |
QA:d8425d3a8b24f10f40eeaec3 | QAG:cce7271328c8f2a6ff8962ab | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "( a ) SCID/Beige mice received a subcutaneous implant of a stable transplant from a patient-derived tumor to establish a xenograft, and then received an intratumoral injection of either LPNP-p198 or LPNP-Ctrl in combination with intraperitoneal injection of gemcitabine... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:768e2da19b469da32822a9fc","quotes":["Figure 3 In vivo delivery of miR-198 sensitizes PDAC cells to gemcitabine, l... | [
"CLM:768e2da19b469da32822a9fc",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:002db9a92132a0fd479f5cf1"
] | [] | [] | {"qa_id":"QA:d8425d3a8b24f10f40eeaec3","qa_group_id":"QAG:cce7271328c8f2a6ff8962ab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"( a ) SCID/Beige mice received a subcutaneous implant of a stable ... |
QA:d85e1757334b9cd2938d7d49 | QAG:e112742e5d5dc49daf6db7d6 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Having shown that intravenous injection of LPNP-p198 inhibited tumor growth in an orthotopic PDAC mouse model through VCP-downregulation-mediated sensitization to gemcitabine treatment, we sought to further delve into the clinical relevance of LPNP-mediated therapy by ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4b20c5703b38e1fcf3e166b1","quotes":["Having shown that intravenous injection of LPNP-p198 inhibited tumor growth ... | [
"CLM:4b20c5703b38e1fcf3e166b1",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:35324cde9b99cc6bcf0958b8"
] | [] | [] | {"qa_id":"QA:d85e1757334b9cd2938d7d49","qa_group_id":"QAG:e112742e5d5dc49daf6db7d6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Having shown that intravenous injection of LPNP-p198 inhibited tum... |
QA:d8f38b30c1f8e3a9b4a5b3f7 | QAG:a47e6e37898b607ead34ad3c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In addition, we observed that, when administered to a PDAC mouse model, alone or combined with gemcitabine treatment, butyrate markedly decreased the cancer-associated stromatogenesis, preserved intestinal mucosa integrity and affected fecal microbiota composition by i... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1a3fd2aadf01c726b8689a42","quotes":["In addition, we observed that, when administered to a PDAC mouse model, alon... | [
"CLM:1a3fd2aadf01c726b8689a42",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMID:35617803"
] | [
"SPAN:784063bda7f1d2022244654d"
] | [] | [] | {"qa_id":"QA:d8f38b30c1f8e3a9b4a5b3f7","qa_group_id":"QAG:a47e6e37898b607ead34ad3c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In addition, we observed that, when administered to a PDAC mouse m... |
QA:d92c150dad0fdb45fe8968e8 | QAG:687fec430205459ebbd58a22 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "For ECON exposure, we clarified the relationship between ECON promoted autophagy and apoptosis in PDAC cells, thus providing a logical explanation for its potent therapeutic responses against PDAC"? Return the original wording with paper, Claim, and Evidence Span refer... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:88e84c7128a4a883b3a8924b","quotes":["For ECON exposure, we clarified the relationship between ECON-induced autoph... | [
"CLM:88e84c7128a4a883b3a8924b",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:f09b56c0b3b68e66c85c0a99"
] | [] | [] | {"qa_id":"QA:d92c150dad0fdb45fe8968e8","qa_group_id":"QAG:687fec430205459ebbd58a22","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"For ECON exposure, we clarified the relationship between ECON prom... |
QA:da1892282afe6f76f75bc7e3 | QAG:db55bd9203d0b44cf056d089 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "( a ) SCID/Beige mice received a subcutaneous implant of a stable transplant from a patient-derived tumor to establish a xenograft, and then received an intratumoral injection of either LPNP-p198 or LPNP-Ctrl in combination with intraperitoneal injection of gemcitabine... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6120c5f536bf620189041159","quotes":["Figure 3 In vivo delivery of miR-198 sensitizes PDAC cells to gemcitabine, l... | [
"CLM:6120c5f536bf620189041159",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10457905"
] | [
"SPAN:002db9a92132a0fd479f5cf1"
] | [] | [] | {"qa_id":"QA:da1892282afe6f76f75bc7e3","qa_group_id":"QAG:db55bd9203d0b44cf056d089","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"( a ) SCID/Beige mice received a subcutaneous implant of a stable ... |
QA:db33f02de6e4c55310518df5 | QAG:ec163cda5d1c9d2d1f57787f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Together, our current work demonstrated that BNIP3 promoted autophagy was involved in the migration and proliferation of PDAC cells under hypoxia"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5893b5b7200f058f7c9df9a2","quotes":["Together, our current work demonstrated that BNIP3-induced autophagy was inv... | [
"CLM:5893b5b7200f058f7c9df9a2",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9614569"
] | [
"SPAN:1bb3514ec155ad310ff8704b"
] | [] | [] | {"qa_id":"QA:db33f02de6e4c55310518df5","qa_group_id":"QAG:ec163cda5d1c9d2d1f57787f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Together, our current work demonstrated that BNIP3 promoted autoph... |
QA:db84d6aa2d6a595f11ddc6dd | QAG:ab8fc73e209552e9252d25ea | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "11 , 12 , 13 , 14 , 15 It was also reported that the inhibition of SCD inhibited the growth of pancreatic cancer cells in vitro and in the transgenic mouse model Pdx1-Cre;LSL-Kras G12D in vivo"? Return the original wording with paper, Claim, and Evidence Span reference... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:28d67f77f1dabbfb3861bb66","quotes":["11 , 12 , 13 , 14 , 15 It was also reported that the inhibition of SCD suppr... | [
"CLM:28d67f77f1dabbfb3861bb66",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9794976"
] | [
"SPAN:dcd396142453b8f2813bdcf0"
] | [] | [] | {"qa_id":"QA:db84d6aa2d6a595f11ddc6dd","qa_group_id":"QAG:ab8fc73e209552e9252d25ea","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"11 , 12 , 13 , 14 , 15 It was also reported that the inhibition of... |
QA:dd146e920f4f4d95a327a865 | QAG:4d1fcf18ea0e2574a27ee2bf | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Additional file 5: Figure S5 LIPH-LPA-LPAR axis increased PDAC glycolysis and viability by activating hypoxia and Hippo pathways"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact support... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:84ef9ce8ebc0cc29fced68e0","quotes":["D Oxygen consumption rate (OCR) detected by Seahorse analyzer (O: oligomycin... | [
"CLM:84ef9ce8ebc0cc29fced68e0",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:97701a7c42ae05398c951a8d"
] | [] | [] | {"qa_id":"QA:dd146e920f4f4d95a327a865","qa_group_id":"QAG:4d1fcf18ea0e2574a27ee2bf","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Additional file 5: Figure S5 LIPH-LPA-LPAR axis increased PDAC gly... |
QA:de246ff4a9f7b8f6244c24e0 | QAG:c4ade2339aee5ad558b5efae | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "( 18 )] in CAFs, when they were cocultured with autophagy inhibited PDAC ( Fig. 8B )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2cc00554d0c9ab5fdd95515a","quotes":["We saw an increase in iron exporter ferroportin [FPN; encoded by SLC40A1 gen... | [
"CLM:2cc00554d0c9ab5fdd95515a",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10115412"
] | [
"SPAN:34d53f55951fa087e734430c"
] | [] | [] | {"qa_id":"QA:de246ff4a9f7b8f6244c24e0","qa_group_id":"QAG:c4ade2339aee5ad558b5efae","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"( 18 )] in CAFs, when they were cocultured with autophagy inhibite... |
QA:dfa3addc3e654e16b9b90563 | QAG:38a7ea2a85628deb32d8820c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Accordingly, pharmacological inhibition of autophagy increased extracellular lipid restriction-mediated induction of cell death and inhibited PDAC growth"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements:... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7d06d43c874b148a98912003","quotes":["Accordingly, pharmacological inhibition of autophagy enhanced extracellular ... | [
"CLM:7d06d43c874b148a98912003",
"CLM:0b37c68891bec8045dae723d"
] | [
"PMCID:PMC8742413"
] | [
"SPAN:6925fae1c5edcba5b971380c"
] | [] | [] | {"qa_id":"QA:dfa3addc3e654e16b9b90563","qa_group_id":"QAG:38a7ea2a85628deb32d8820c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Accordingly, pharmacological inhibition of autophagy increased ext... |
QA:e140d8d547ada987bb496d20 | QAG:fbc1c5dcf7a5861a590a6d0a | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "VIT2763 prevented the LIP compensation from CAFs in autophagy inhibited PDAC under coculture conditions, leading to impaired PDAC proliferation ( Fig. 9, C and D )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance req... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:53cb1da364286c8e5a0d3af4","quotes":["VIT2763 prevented the LIP compensation from CAFs in autophagy-inhibited PDAC... | [
"CLM:53cb1da364286c8e5a0d3af4",
"CLM:2344f7fe98dcb10347598658"
] | [
"PMCID:PMC10115412"
] | [
"SPAN:84bf4c2677b36b7b3b7caa62"
] | [] | [] | {"qa_id":"QA:e140d8d547ada987bb496d20","qa_group_id":"QAG:fbc1c5dcf7a5861a590a6d0a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"VIT2763 prevented the LIP compensation from CAFs in autophagy inhi... |
QA:e180f696f263b775b70c7578 | QAG:e9621aca11eeae2235389c8c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These results were highly consistent with our in vitro findings that LIPH knockdown inhibited the proliferation and promoted the apoptosis of pancreatic cancer cells in vitro"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated pro... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dfb4a8798b7258285031a862","quotes":["These results were highly consistent with our in vitro findings that LIPH kn... | [
"CLM:dfb4a8798b7258285031a862",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10664664"
] | [
"SPAN:f37cc17e94d1990d05fb2413"
] | [] | [] | {"qa_id":"QA:e180f696f263b775b70c7578","qa_group_id":"QAG:e9621aca11eeae2235389c8c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These results were highly consistent with our in vitro findings th... |
QA:e19cd31bbfe485281efe599e | QAG:b5fa2eb3804c110b983dd013 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 1 BNIP3 increased the migration and proliferation of pancreatic cancer cells under hypoxia"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:06e45ba4d376ec8632cf340c","quotes":["Figure 1 BNIP3 enhanced the migration and proliferation of pancreatic cancer... | [
"CLM:06e45ba4d376ec8632cf340c",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9614569"
] | [
"SPAN:89a5d7d176e698ce8dbac750"
] | [] | [] | {"qa_id":"QA:e19cd31bbfe485281efe599e","qa_group_id":"QAG:b5fa2eb3804c110b983dd013","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 1 BNIP3 increased the migration and proliferation of pancre... |
QA:e348385790c3999db910833d | QAG:aa917baa7a7e59d5a1d4f735 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "We observed a heterogeneous expression of GS in both human and mouse PDAC lines, with most not displaying increased expression on DON treatment"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return th... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:30b803f2710829afd24627b5","quotes":["First, we evaluated the levels and activity of Gln synthetase (GS) in vitro,... | [
"CLM:30b803f2710829afd24627b5",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10824664"
] | [
"SPAN:bc97c85afc08a9b6e4fb4abd"
] | [] | [] | {"qa_id":"QA:e348385790c3999db910833d","qa_group_id":"QAG:aa917baa7a7e59d5a1d4f735","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"We observed a heterogeneous expression of GS in both human and mou... |
QA:e6c7d1b526fccda39765bc7b | QAG:5ad21efbdc2a5d8b27bfd39e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These data demonstrate that dysfunctional autophagy promoted by ECON elicits ER stress-mediated apoptosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper,... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7208be114a95482987d50c60","quotes":["These data demonstrate that dysfunctional autophagy induced by ECON elicits ... | [
"CLM:7208be114a95482987d50c60",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9293665"
] | [
"SPAN:0657713b3640a4382b85be1a",
"SPAN:1f5f1cdc100d8df1eb9805d1"
] | [] | [] | {"qa_id":"QA:e6c7d1b526fccda39765bc7b","qa_group_id":"QAG:5ad21efbdc2a5d8b27bfd39e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These data demonstrate that dysfunctional autophagy promoted by EC... |
QA:e7c3690000846050e0f3fe1d | QAG:92b62ad5fb10028ab2adea60 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Further, we found that increased lipid raft cholesterol content in PDAC cells is associated with activated AKT survival signaling and PDAC chemo-resistance, as depletion of CRABP-II not only decreased lipid raft cholesterol level but also inhibited AKT activation and i... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:301d0f75305d7d91afd8cd27","quotes":["Further, we found that increased lipid raft cholesterol content in PDAC cell... | [
"CLM:301d0f75305d7d91afd8cd27",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:1fb9e0dfea1cfc926ba3ed6e"
] | [] | [] | {"qa_id":"QA:e7c3690000846050e0f3fe1d","qa_group_id":"QAG:92b62ad5fb10028ab2adea60","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Further, we found that increased lipid raft cholesterol content in... |
QA:ea7c3a623bdebeb087bffa3e | QAG:47819472a5de97cf299650a2 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In this study, we found that NMU was a prognostic factor for patients with PDAC and may regulate the anti‐tumor activity of CD8 + T cells in the TME in an NMUR1‐dependent manner"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3423306c651f98650f2cd22d","quotes":["In this study, we found that NMU is an independent prognostic factor for pat... | [
"CLM:3423306c651f98650f2cd22d",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10859610"
] | [
"SPAN:2e86e0356dc84379ad992c43"
] | [] | [] | {"qa_id":"QA:ea7c3a623bdebeb087bffa3e","qa_group_id":"QAG:47819472a5de97cf299650a2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In this study, we found that NMU was a prognostic factor for patie... |
QA:ea89ef235e444f564b98ca8d | QAG:7cc9d6e7e966038700306756 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Glycolysis can be promoted by hypoxia and is reported to promote tumor progression and chemoresistance in PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d12db10b1a1c76a73f1b30de","quotes":["Glycolysis can be induced by hypoxia and is reported to promote tumor progre... | [
"CLM:d12db10b1a1c76a73f1b30de",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:5612c287f5617ce8e67b70ad"
] | [] | [] | {"qa_id":"QA:ea89ef235e444f564b98ca8d","qa_group_id":"QAG:7cc9d6e7e966038700306756","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Glycolysis can be promoted by hypoxia and is reported to promote t... |
QA:eaa1bdf92cde02c87ffa6df7 | QAG:82c5ac9ef5479b7f1973d53d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "It was noticed that PYGL expression of HPNE cell was lower than that of the majority of PDAC cells at protein level ( Figure S4 B)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact suppo... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f964ef5cc1f00f7757f27ff3","quotes":["It was noticed that PYGL expression of HPNE cell was lower than that of the ... | [
"CLM:f964ef5cc1f00f7757f27ff3",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:a4cb23da1141fee962280d29"
] | [] | [] | {"qa_id":"QA:eaa1bdf92cde02c87ffa6df7","qa_group_id":"QAG:82c5ac9ef5479b7f1973d53d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"It was noticed that PYGL expression of HPNE cell was lower than th... |
QA:eac48039a3a06b76b4d13254 | QAG:a74dd95d6067e1a1f03089cf | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In conclusion, we propose that, when CHK1 inhibition is not sufficient to induce S-phase arrest, PDAC cells then rely on RIF1 for NHEJ and/or replication fork protection to escape from CHK1i promoted apoptosis"? Return the original wording with paper, Claim, and Eviden... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a6489599551b3c412c6fe41","quotes":["In conclusion, we propose that, when CHK1 inhibition is not sufficient to in... | [
"CLM:9a6489599551b3c412c6fe41",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8665414"
] | [
"SPAN:885a83bc9874138e107f2a9d"
] | [] | [] | {"qa_id":"QA:eac48039a3a06b76b4d13254","qa_group_id":"QAG:a74dd95d6067e1a1f03089cf","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In conclusion, we propose that, when CHK1 inhibition is not suffic... |
QA:ebf10ffb98c4cf48a40406b9 | QAG:de812fb401bc406f4c8f706f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In line with the results on intracellular GAPDH activity, only AXP-3009 and AXP-3019 compounds inhibited PDAC cell proliferation in a concentration-dependent manner"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance re... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b1c74b0ec25f0877f5b62309","quotes":["In line with the results on intracellular GAPDH activity, only AXP-3009 and ... | [
"CLM:b1c74b0ec25f0877f5b62309",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:e9f0ba1fd6baac02721e22fc"
] | [] | [] | {"qa_id":"QA:ebf10ffb98c4cf48a40406b9","qa_group_id":"QAG:de812fb401bc406f4c8f706f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In line with the results on intracellular GAPDH activity, only AXP... |
QA:f0b1be52ed824595f5ba790d | QAG:902e4716304284899880ec1c | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "These results suggest that OBP-702 promoted ICD in human PDAC cells is associated with p53-mediated induction of apoptosis and autophagy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c49972610a0f45a0a276685a","quotes":["These results suggest that OBP-702-induced ICD in human PDAC cells is associ... | [
"CLM:c49972610a0f45a0a276685a",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9513735"
] | [
"SPAN:d30047e02ef77e2799b99770"
] | [] | [] | {"qa_id":"QA:f0b1be52ed824595f5ba790d","qa_group_id":"QAG:902e4716304284899880ec1c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"These results suggest that OBP-702 promoted ICD in human PDAC cell... |
QA:f0f6d2da975bd93cf21dacd5 | QAG:63f524487c91d8165e4d4082 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Here, we analyzed the differentially expressed genes between classical PDAC and quasimesenchymal PDAC (QM-PDAC) tissues from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets ( GSE15471 , GSE16515 , and GSE17891 ), and found that the expression ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5970c841d40a57972976874e","quotes":["Here, we analyzed the differentially expressed genes between classical PDAC ... | [
"CLM:5970c841d40a57972976874e",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:299549af9156fac1fb5ff971"
] | [] | [] | {"qa_id":"QA:f0f6d2da975bd93cf21dacd5","qa_group_id":"QAG:63f524487c91d8165e4d4082","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Here, we analyzed the differentially expressed genes between class... |
QA:f12cd0287c9955c2e9d15f2a | QAG:79b555712251d88a1d535ff7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "PYGL expression is increased in PDAC tissues and positively associated with prognosis for PDAC patients"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, C... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1e0896953029b1c94575ec02","quotes":["PYGL expression is increased in PDAC tissues and positively associated with ... | [
"CLM:1e0896953029b1c94575ec02",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10092766"
] | [
"SPAN:fe0bec985d89fbddd6ac19c0"
] | [] | [] | {"qa_id":"QA:f12cd0287c9955c2e9d15f2a","qa_group_id":"QAG:79b555712251d88a1d535ff7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"PYGL expression is increased in PDAC tissues and positively associ... |
QA:f153d358cbabf418fd97b35b | QAG:c49a78d8c6e9a32c3a3ae42f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Moreover, in addition to AKT pathway, other signaling pathways such as the sonic hedgehog (SHH) and the mucin MUC1 & Src signaling may be impacted by CRABP-II promoted lipid raft cholesterol accumulation and contribute to PDAC chemo-resistance"? Return the original wor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5f2478895a330f6eb3ea0864","quotes":["Moreover, in addition to AKT pathway, other signaling pathways such as the s... | [
"CLM:5f2478895a330f6eb3ea0864",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:cce592feff9f21c4c3e87967"
] | [] | [] | {"qa_id":"QA:f153d358cbabf418fd97b35b","qa_group_id":"QAG:c49a78d8c6e9a32c3a3ae42f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Moreover, in addition to AKT pathway, other signaling pathways suc... |
QA:f1f3acfa9901593b6b16f716 | QAG:9eb662ddf124d059e0ee0aec | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 8 GbcxMRS predicted drug sensitivity in PDAC. ( a , b ) The estimated drug sensitivity (log AUC) for 5-fluorouracil, irinotecan, and docetaxel between the high and low gbcxMRS groups in the ( a ) E-MTAB-6134 and ( b ) ICGC cohorts. ( c , d ) Submap analysis indi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:63a052b04d981e37f6106e77","quotes":["Figure 8 GbcxMRS predicted drug sensitivity in PDAC. ( a , b ) The estimated... | [
"CLM:63a052b04d981e37f6106e77",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8997486"
] | [
"SPAN:12a4ef7f3a9f1b537d731016"
] | [] | [] | {"qa_id":"QA:f1f3acfa9901593b6b16f716","qa_group_id":"QAG:9eb662ddf124d059e0ee0aec","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 8 GbcxMRS predicted drug sensitivity in PDAC. ( a , b ) The... |
QA:f3c96b44808da8398c638d85 | QAG:b7c5ca9804c9a200945fb889 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "PDAC parental (P) cells and cancer stem cells (CSCs) received the h GAPDH inhibitors AXP-3018 or AXP-3019 at 1 μM or 10 μM. ( a ) Representative images of parental and CSCs after stemness induction. ( b , c ) Percentage of cell proliferation of parental (P) and CSCs af... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:61ed32095431aefa693ae99a","quotes":["PDAC parental (P) cells and cancer stem cells (CSCs) were treated with the h... | [
"CLM:61ed32095431aefa693ae99a",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9264795"
] | [
"SPAN:f141e3f8845b6e4c09a9521f"
] | [] | [] | {"qa_id":"QA:f3c96b44808da8398c638d85","qa_group_id":"QAG:b7c5ca9804c9a200945fb889","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"PDAC parental (P) cells and cancer stem cells (CSCs) received the ... |
QA:f49f06f27ca693a7340519b7 | QAG:8971c1ad59f8ce6109bf1134 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Treatment of Panc1 and MiaPaca2 pancreatic cancer cells with gemcitabine promoted expression of the orphan nuclear receptor 4A2 (NURR1) and analysis of The Cancer Genome Atlas indicated the NURR1 is overexpressed in pancreatic tumors and is a negative prognostic factor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:93d023c4a19e2fe054127b08","quotes":["Treatment of Panc1 and MiaPaca2 pancreatic cancer cells with gemcitabine ind... | [
"CLM:93d023c4a19e2fe054127b08",
"CLM:0254266c32c41ab5d504f862"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:80f49d55f3e1dcc4813f1403"
] | [] | [] | {"qa_id":"QA:f49f06f27ca693a7340519b7","qa_group_id":"QAG:8971c1ad59f8ce6109bf1134","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Treatment of Panc1 and MiaPaca2 pancreatic cancer cells with gemci... |
QA:f4a4252352467d62a9d973db | QAG:6a20344fad20522323b2fb0f | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Gemcitabine-resistant cell lines exhibited increased level of CRABP-II, while CRABP-II knockout resensitized PDAC cells to gemcitabine"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact s... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:78b041996ae639f98b0d05c7","quotes":["Gemcitabine-resistant cell lines exhibited increased level of CRABP-II, whil... | [
"CLM:78b041996ae639f98b0d05c7",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8903155"
] | [
"SPAN:7cdb811e60b081e68e5769f8"
] | [] | [] | {"qa_id":"QA:f4a4252352467d62a9d973db","qa_group_id":"QAG:6a20344fad20522323b2fb0f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Gemcitabine-resistant cell lines exhibited increased level of CRAB... |
QA:f4af5a44041c9d37578b7b6e | QAG:6339ca378d3ff38533fc1c72 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "All PDOs samples were developed by direct engraftment of pancreatic cancer tissue fragments from patients undergoing surgical resection or biopsy as domes in growth factor decreased Matrigel, expanded and viably frozen at a low passage"? Return the original wording wit... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aa82f393976865ba1e4c99e7","quotes":["All PDOs samples were developed by direct engraftment of pancreatic\ncancer ... | [
"CLM:aa82f393976865ba1e4c99e7",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC10824664"
] | [
"SPAN:24b9e9519f7675a645ba9c10"
] | [] | [] | {"qa_id":"QA:f4af5a44041c9d37578b7b6e","qa_group_id":"QAG:6339ca378d3ff38533fc1c72","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"All PDOs samples were developed by direct engraftment of pancreati... |
QA:f5b2b9668d22a3850a714057 | QAG:7bd782c0aa6caf7d57bcc75d | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Western blot analysis demonstrated that Ad-p53 promoted apoptosis only in MIA PaCa-2 cells, although the expression of p53 was increased in all human PDAC cells ( Figure S10 )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated pr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:708ae613bd9b219428a3fb5d","quotes":["Western blot analysis demonstrated that Ad-p53 indu... | [
"CLM:708ae613bd9b219428a3fb5d",
"CLM:053ffd7bb6e6ca17b0bc3071",
"CLM:34fe77ea0f1d3337192b1a23",
"CLM:e85e87b35f43388ff5489b66"
] | [
"PMCID:PMC9513735",
"PMCID:PMC9264795",
"PMID:34112559"
] | [
"SPAN:8b24eb48a5c9dd11defb01ae",
"SPAN:6bce490da9af6629c76192a2",
"SPAN:e3a06d1caa4bad858a61ecac"
] | [
"ASC2:3b4ebfb0e0b29ade20247320",
"ASC2:537ac47ab1d7dd322b7c2614"
] | [
"HYP:DCH:170832814b65f0e7e4cc420c"
] | {"qa_id":"QA:f5b2b9668d22a3850a714057","qa_group_id":"QAG:7bd782c0aa6caf7d57bcc75d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Western blot analysis demonstrated that Ad-p53 promoted apoptosis ... |
QA:f9706e1a1c0f2805a4186bb1 | QAG:349420456d313564cc2ce52b | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "PDA is a prime example of a tumor that develops chemoresistance and to investigate the possible relationship between chemotherapeutic drugs and NURR1 expression pancreatic cancer cells received gemcitabine and analysis by immunoblot and immunofluorescence showed that g... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4a34228bb2ceeed0ba277a54","quotes":["PDA is a prime example of a tumor that develops chemoresistance and to inves... | [
"CLM:4a34228bb2ceeed0ba277a54",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC9109828"
] | [
"SPAN:c185282c503327a5907995f4"
] | [] | [] | {"qa_id":"QA:f9706e1a1c0f2805a4186bb1","qa_group_id":"QAG:349420456d313564cc2ce52b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"PDA is a prime example of a tumor that develops chemoresistance an... |
QA:f983f0bfd14286c88c032f29 | QAG:010e44660979b02b30b0504e | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Based on the IL-17RB promoted metabolic changes in PSCs, we hypothesized that PSCs affect the metabolism of pancreatic cancer cells"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supp... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:59b9a94de6cd63ecad48b038","quotes":["Based on the IL-17RB induced metabolic changes in PSCs, we hypothesized that... | [
"CLM:59b9a94de6cd63ecad48b038",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8611647"
] | [
"SPAN:00636afb67ccfde3f1622257"
] | [] | [] | {"qa_id":"QA:f983f0bfd14286c88c032f29","qa_group_id":"QAG:010e44660979b02b30b0504e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Based on the IL-17RB promoted metabolic changes in PSCs, we hypoth... |
QA:f9d74bbfb8bc4c077a6f534b | QAG:59d381a63fcb24e2baa478a6 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "In mouse pancreatic cancer, Acsl3 deletion triggered decreased tumor cell proliferation, in part by impairing the production of the pro-fibrotic plasminogen activator inhibitor-1 (PAI-1), decreasing desmoplasia and immunosuppression"? Return the original wording with p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6161f0b28893457e664af63f","quotes":["In mouse pancreatic cancer, Acsl3 deletion triggered reduced tumor cell prol... | [
"CLM:6161f0b28893457e664af63f",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC8742413"
] | [
"SPAN:b35c106b78924a179552603e"
] | [] | [] | {"qa_id":"QA:f9d74bbfb8bc4c077a6f534b","qa_group_id":"QAG:59d381a63fcb24e2baa478a6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"In mouse pancreatic cancer, Acsl3 deletion triggered decreased tum... |
QA:fa234cde143aa4a226f0e641 | QAG:b5ce3fbfcb6b74f6cc953ed9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Figure 4 Basing on the above-mentioned results, we explored if autophagy regulated BNIP3 promoted pancreatic cancer cell migration and proliferation under hypoxia"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bcd65a7c27b2ff9c49ba0a2c","quotes":["Figure 4 Basing on the above-mentioned results, we explored if autophagy reg... | [
"CLM:bcd65a7c27b2ff9c49ba0a2c",
"CLM:00354d8cbec4dead29bb8637"
] | [
"PMCID:PMC9614569"
] | [
"SPAN:846b6deb4e03e465aeb7fda2"
] | [] | [] | {"qa_id":"QA:fa234cde143aa4a226f0e641","qa_group_id":"QAG:b5ce3fbfcb6b74f6cc953ed9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Figure 4 Basing on the above-mentioned results, we explored if aut... |
QA:fa8d8b7c3d0e9b61b97d4abe | QAG:30fe1c4cf3a669d4600c04bb | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Extending these analyses to patient-derived PDAC organoid cultures, we found that the triple combination also potently inhibited growth of these organoids ( Figures 7F and S10H )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0dd5268202cc6b5cad69882d","quotes":["Extending these analyses to patient-derived PDAC organoid cultures, we found... | [
"CLM:0dd5268202cc6b5cad69882d",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC8665414"
] | [
"SPAN:3f1a1935586030107e999d6b"
] | [] | [] | {"qa_id":"QA:fa8d8b7c3d0e9b61b97d4abe","qa_group_id":"QAG:30fe1c4cf3a669d4600c04bb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Extending these analyses to patient-derived PDAC organoid cultures... |
QA:fd9076e77c6eac24b298c68a | QAG:dfa7fa77587467d7a91b2c55 | provenance_qa | paper_evidence_availability | provenance_qa | G020 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8597267? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC8597267","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC8597267"
] | [] | [] | [] | {"qa_id":"QA:fd9076e77c6eac24b298c68a","qa_group_id":"QAG:dfa7fa77587467d7a91b2c55","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G020","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8597267... |
QA:fe60fe75d24d23eeff960377 | QAG:a3ab296f7bd983558a0186cc | provenance_qa | exact_evidence_retrieval | provenance_qa | G020 | en | train | Which exact source passage supports the statement "Remarkably, DRP-104 decreased tumor growth in two independent orthotopic syngeneic PDAC models after two cycles of treatment (Fig. 2b)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact s... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0dd5c5e1e82d91c8cefc8915","quotes":["Remarkably, DRP-104 significantly reduced\ntumor growth in two independent o... | [
"CLM:0dd5c5e1e82d91c8cefc8915",
"CLM:03219ae941a2b333b95944b3"
] | [
"PMCID:PMC10824664"
] | [
"SPAN:a8049f510b0d48a96e475c3d"
] | [] | [] | {"qa_id":"QA:fe60fe75d24d23eeff960377","qa_group_id":"QAG:a3ab296f7bd983558a0186cc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G020","question":"Which exact source passage supports the statement \"Remarkably, DRP-104 decreased tumor growth in two independent orth... |
QA:04b05b225572e0ce744323c2 | QAG:6417d883ca850fd60879a83c | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In contrast to many other tumor entities, the prognosis of PDAC has not improved during the past thirty years"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with pa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:326ca9ff376e913719135fea","quotes":["In contrast to many other tumor entities, the prognosis of PDAC has not sign... | [
"CLM:326ca9ff376e913719135fea",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC7598647"
] | [
"SPAN:731fb3d15a2d7ad7da79ab68"
] | [] | [] | {"qa_id":"QA:04b05b225572e0ce744323c2","qa_group_id":"QAG:6417d883ca850fd60879a83c","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In contrast to many other tumor entities, the prognosis of PDAC ha... |
QA:061ce690c8c82cc497d79a91 | QAG:94aa701fa5fa66d1c554ff24 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "More importantly we have shown that ANXA11 and GPC4 signals was higher than plasma of PDAC patients as compared with subjects with benign GI diseases ( P < 0.05, Figure 8B )"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated prov... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f0b11f4c71d93e897cb1b713","quotes":["More importantly we have shown that ANXA11 and GPC4 signals were significant... | [
"CLM:f0b11f4c71d93e897cb1b713",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC7710298"
] | [
"SPAN:4c990f48f7f67ae8f0e64701"
] | [] | [] | {"qa_id":"QA:061ce690c8c82cc497d79a91","qa_group_id":"QAG:94aa701fa5fa66d1c554ff24","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"More importantly we have shown that ANXA11 and GPC4 signals was hi... |
QA:0690ceab7d147cdc3211a7b1 | QAG:18d89ffedaac983cb8181e40 | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6125219? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC6125219","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC6125219"
] | [] | [] | [] | {"qa_id":"QA:0690ceab7d147cdc3211a7b1","qa_group_id":"QAG:18d89ffedaac983cb8181e40","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC6125219... |
QA:0a5890c8e8c40df582b6f24a | QAG:0fb5d6bede2e35ba41fcfa6e | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In vitro and in vivo validation using PDO, PDX and KPC mouse models showed that irbesartan efficiently sensitized to chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact suppor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0595c56a1ea6580a9230d904","quotes":["In vitro and in vivo valid... | [
"CLM:0595c56a1ea6580a9230d904",
"CLM:0318813e4f6821e1817a7015",
"CLM:31ea4d3f996a9f8a13dda8dd",
"CLM:db029afc2293c014efb4b787",
"CLM:48c63c07ec6922389d8f68f8"
] | [
"PMCID:PMC10157938",
"PMID:37522250",
"PMCID:PMC10060271"
] | [
"SPAN:4766ce43dd867a0a3a6b4124",
"SPAN:ccff93b9869631e2a94401f7",
"SPAN:08b3e1e7e59b706fca48fec6",
"SPAN:09c4b4174e3289dceed43948"
] | [
"ASC2:d71ecbe5903185ef4000163a",
"ASC2:571f4c81a23742424ee1bff6"
] | [
"HYP:DCH:161a3aa410e5081b1fd82217",
"HYP:DCH:973e588da9c821faca1a3dc1"
] | {"qa_id":"QA:0a5890c8e8c40df582b6f24a","qa_group_id":"QAG:0fb5d6bede2e35ba41fcfa6e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In vitro and in vivo validation using PDO, PDX and KPC mouse model... |
QA:0a5e78db2b81103f937a9c00 | QAG:b69d588f348a7a1e4b1ca9f8 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Four other glycans (H3N4F1, H3N2F1, H2N2F1, and H3N3F1) contained Lewis-X epitope (H(1,4)-Fα(1,3)-N) that was increased in PDAC and colon tumor tissues compared with normal ( 26 , 27 ), demonstrating that PXO models retained glycosylation changes previously reported to... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:70add7701dea400b41df4830","quotes":["Four other glycans (H3N4F1, H3N2F1, H2N2F1, and H3N3F1) contained Lewis-X ep... | [
"CLM:70add7701dea400b41df4830",
"CLM:065ed27ad3615b0a901fd1b8"
] | [
"PMCID:PMC7710298"
] | [
"SPAN:863cd125f8dc4b9363efd99f"
] | [] | [] | {"qa_id":"QA:0a5e78db2b81103f937a9c00","qa_group_id":"QAG:b69d588f348a7a1e4b1ca9f8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Four other glycans (H3N4F1, H3N2F1, H2N2F1, and H3N3F1) contained ... |
QA:0b4fabf46c577601da26da30 | QAG:9e643edac2f4e1886c1c1569 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "green = decreased potency)"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; assess the embedded target Claim only aga... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:85a16d1a7d0ccb689343fdab","quotes":["Figure 3. ( A ) Heat map of the activity of 114 NCI oncology drugs associate... | [
"CLM:85a16d1a7d0ccb689343fdab",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMCID:PMC6013403"
] | [
"SPAN:22d31e8f29ab06783fc36ce7"
] | [] | [] | {"qa_id":"QA:0b4fabf46c577601da26da30","qa_group_id":"QAG:9e643edac2f4e1886c1c1569","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"green = decreased potency)\"? Return the original wording with pap... |
QA:0bf832173c8cbf31cf5c1e56 | QAG:8570bd3391ac5b1ef7164423 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "11 Tumoral c-Jun expression level predicted the efficacy of chemotherapy and irbesartan plus chemotherapy regimens in human PDAC patients"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exac... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e92d006404d488936253bc8f","quotes":["Fig. 11 Tumoral c-Jun expression level predicts the efficacy of chemotherapy... | [
"CLM:e92d006404d488936253bc8f",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:f6c4beb713b66180e6fa97f0"
] | [] | [] | {"qa_id":"QA:0bf832173c8cbf31cf5c1e56","qa_group_id":"QAG:8570bd3391ac5b1ef7164423","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"11 Tumoral c-Jun expression level predicted the efficacy of chemot... |
QA:0d0efa1b0df9facb1412ac07 | QAG:2a36ca45e9a30047d13d3e12 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "The Cohort3# contained 60 patients with advanced (stage III/IV) PDAC who received GEM/nab-paclitaxel chemotherapy at Tianjin Medical University Affiliated Cancer Institute and Hospital and all the patients were diagnosed with hypertension"? Return the original wording ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a40e3b099ebc7880bcdd6952","quotes":["The Cohort3# contained 60 patients with advanced (stage III/IV) PDAC who rec... | [
"CLM:a40e3b099ebc7880bcdd6952",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:d8a092aed386ddbf8ac70b9d"
] | [] | [] | {"qa_id":"QA:0d0efa1b0df9facb1412ac07","qa_group_id":"QAG:2a36ca45e9a30047d13d3e12","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"The Cohort3# contained 60 patients with advanced (stage III/IV) PD... |
QA:0fe4aa024b23d9c3b03dcfb0 | QAG:fbc47dca5c99eff2f8d688db | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7268941? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC7268941","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC7268941"
] | [] | [] | [] | {"qa_id":"QA:0fe4aa024b23d9c3b03dcfb0","qa_group_id":"QAG:fbc47dca5c99eff2f8d688db","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7268941... |
QA:12c63b24c35e1698cdbdb83c | QAG:992d0ab7150e5c1f84a5aed4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In addition, multiplexed staining and TissueFAXS analysis in archived tissues from a retrospective cohort of 95 PDAC patients showed that the counts of CD133 + cells and ALDH1 + cells per high-power field were notably increased in the high-c-Jun group compared with in ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e973c97823b93ae518fc734e","quotes":["In addition, multiplexed staining and TissueFAXS analysis in archived tissue... | [
"CLM:e973c97823b93ae518fc734e",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:78fe460c7c429209598ea03f"
] | [] | [] | {"qa_id":"QA:12c63b24c35e1698cdbdb83c","qa_group_id":"QAG:992d0ab7150e5c1f84a5aed4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In addition, multiplexed staining and TissueFAXS analysis in archi... |
QA:13d775c1455aa444df1ae2f1 | QAG:2bbb76666c5a214a0201acff | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Another retrospective cohort containing 104 patients who were pathologically diagnosed with advanced PDAC based on pancreatic needle biopsy at the Tianjin Medical University Cancer Institute and Hospital, China, between Jul 2015 and Jun 2020 were enrolled in this study... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e6e480820f63ef4b4043e3aa","quotes":["Another retrospective cohort containing 104 patients who were pathologically... | [
"CLM:e6e480820f63ef4b4043e3aa",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:a81e7f291cec3a54688f21a7"
] | [] | [] | {"qa_id":"QA:13d775c1455aa444df1ae2f1","qa_group_id":"QAG:2bbb76666c5a214a0201acff","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Another retrospective cohort containing 104 patients who were path... |
QA:17b8a8cbea69fbd9d4f45b9d | QAG:bff5557fe41e9c4de95a0296 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "described an overall success rate of expanding PDTOs from PDAC to drug screening of 63%, but this was decreased to 27% when using percutaneous needle biopsies from primary tumors (despite using larger 16–18 G needles), suggesting that PDTO establishment from the primar... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c5c7e357a858f4cf68ba6878","quotes":["Likewise, Beutel et al. [ 5 ] described an overall success rate of expanding... | [
"CLM:c5c7e357a858f4cf68ba6878",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC10377599"
] | [
"SPAN:9c917e939809b013cb4dff33"
] | [] | [] | {"qa_id":"QA:17b8a8cbea69fbd9d4f45b9d","qa_group_id":"QAG:bff5557fe41e9c4de95a0296","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"described an overall success rate of expanding PDTOs from PDAC to ... |
QA:1ae11c491bbc62d70cef5833 | QAG:fbefa8e586d5c2a6f68ef078 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "A , B Cell death of PDAC organoids promoted by gemcitabine, 5-FU and paclitaxel was significantly reduced when co-cultured with CAFs"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact sup... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31f6a7c8382033a49672df34","quotes":["A , B Cell death of PDAC o... | [
"CLM:31f6a7c8382033a49672df34",
"CLM:0595c56a1ea6580a9230d904",
"CLM:bdc47ee128bed46c88809384",
"CLM:2786284b3fac77ee2930090f",
"CLM:4cda3fb211dad38b1cb55ea2"
] | [
"PMCID:PMC9588250",
"PMCID:PMC6525827",
"PMCID:PMC9645660"
] | [
"SPAN:4dbab276e46ce62231a5470e",
"SPAN:71312f60dc1686dba71e33a9",
"SPAN:30217728cd510d1c7e6e33d9",
"SPAN:b46aa9c3e528dc03aaf3c013"
] | [
"ASC2:ca0a91f2895843a1e9e1e511",
"ASC2:4dae21aa11c27bb3e9503c5f"
] | [
"HYP:DCH:1a3b9305e0ed5c7173c18c9b",
"HYP:DCH:c26b1a004ea08f5cf9e7f666"
] | {"qa_id":"QA:1ae11c491bbc62d70cef5833","qa_group_id":"QAG:fbefa8e586d5c2a6f68ef078","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"A , B Cell death of PDAC organoids promoted by gemcitabine, 5-FU a... |
QA:1b8041dcc2854fd9263731a8 | QAG:764afe52e5bbcf9db96faa37 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In cohorts of surgically treated PDAC patients, the HNF1A + subtype was associated with the best, whereas the KRT81 + subtypes with the worst survival prognosis"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requir... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:45fb2efbef202a2b3fda1e50","quotes":["In cohorts of surgically treated PDAC patients, the HNF1A + subtype was asso... | [
"CLM:45fb2efbef202a2b3fda1e50",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC6525827"
] | [
"SPAN:046cefbcb5b7b60f67399d30"
] | [] | [] | {"qa_id":"QA:1b8041dcc2854fd9263731a8","qa_group_id":"QAG:764afe52e5bbcf9db96faa37","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In cohorts of surgically treated PDAC patients, the HNF1A + subtyp... |
QA:1c694edb2037a93f892d7fd6 | QAG:ebbe500504288e5bf30f5eec | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Organoids showed increased expression of genes associated with epithelial-to-mesenchymal transition (EMT) in co-cultures and several potential receptor-ligand interactions related to EMT were identified, supporting a key role of CAF-driven induction of EMT in PDAC chem... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c119a00c0168d0da086c5078","quotes":["Organoids showed increased expression of genes asso... | [
"CLM:c119a00c0168d0da086c5078",
"CLM:0318813e4f6821e1817a7015",
"CLM:cba2643c61319a5f18e32b5d"
] | [
"PMCID:PMC9588250",
"PMCID:PMC10709344"
] | [
"SPAN:ef03d34f248d043341d41bd7",
"SPAN:9e229fca8a7f04139a0aeb9d"
] | [
"ASC2:170db37f3f62d62e1969a9bb"
] | [] | {"qa_id":"QA:1c694edb2037a93f892d7fd6","qa_group_id":"QAG:ebbe500504288e5bf30f5eec","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Organoids showed increased expression of genes associated with epi... |
QA:1cdebb31cb62b0fc75db7d9a | QAG:923617a109c1c53ae887d66f | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Another cohort containing 60 patients with hypertension who were pathologically diagnosed with advanced PDAC based on pancreatic needle biopsy at Tongliao City Hospital, China, between Jan 2018 and Jan 2020 were enrolled in this study"? Return the original wording with... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c52d6f776f4b3f5727efecc7","quotes":["Another cohort containing 60 patients with hypertension who were pathologica... | [
"CLM:c52d6f776f4b3f5727efecc7",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:de173188da29b344ada75b3e"
] | [] | [] | {"qa_id":"QA:1cdebb31cb62b0fc75db7d9a","qa_group_id":"QAG:923617a109c1c53ae887d66f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Another cohort containing 60 patients with hypertension who were p... |
QA:1eddccc84b9c417349ab69e7 | QAG:a41b50ff8460cbae0f43cd1d | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "D - G Advanced PDAC patients in Cohort2# received GEM/nab-paclitaxel chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Spa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:804932f4b3843253e3922ae7","quotes":["D - G Advanced PDAC patients in Cohort2# received GEM/nab-paclitaxel chemoth... | [
"CLM:804932f4b3843253e3922ae7",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:361124e9a9924b1b0605c185"
] | [] | [] | {"qa_id":"QA:1eddccc84b9c417349ab69e7","qa_group_id":"QAG:a41b50ff8460cbae0f43cd1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"D - G Advanced PDAC patients in Cohort2# received GEM/nab-paclitax... |
QA:2077387a27829ef3abd80e3b | QAG:b748849ba1bc315e9c548d92 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "A total of 95 patients who had received radical surgical R0 resection with a histological diagnosis of PDAC at the Tianjin Medical University Cancer Institute and Hospital, China between July 2011 and January 2015 were retrospectively enrolled in this study"? Return th... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bc796ef21075b14eba77faef","quotes":["A total of 95 patients who had received radical surgical R0 resection with a... | [
"CLM:bc796ef21075b14eba77faef",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:ef738766d90e99d2eddbcb10"
] | [] | [] | {"qa_id":"QA:2077387a27829ef3abd80e3b","qa_group_id":"QAG:b748849ba1bc315e9c548d92","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"A total of 95 patients who had received radical surgical R0 resect... |
QA:208fec77e4be92ab025f4666 | QAG:ec4c2665f6065a44963a709e | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC11022279? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiabl... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC11022279","verdict":"no_released_traceable_claim","reason":"No... | [] | [
"PMCID:PMC11022279"
] | [] | [] | [] | {"qa_id":"QA:208fec77e4be92ab025f4666","qa_group_id":"QAG:ec4c2665f6065a44963a709e","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC1102227... |
QA:235112f9353fbd626b8ee73e | QAG:93e3c9031ca17f2060a5ba1d | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In our study, we established a biobank of genetically distinct human PDAC organoid lines and showed that the morphology, genetic background and drug response of the PDAC organoids was correlated with those observed in the corresponding primary PDAC tissues and patients... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fcbab87a4479b835d1438cbf","quotes":["In our study, we established a biobank of genetically distinct human PDAC or... | [
"CLM:fcbab87a4479b835d1438cbf",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:1cea3149b188cd036c3a62e2"
] | [] | [] | {"qa_id":"QA:235112f9353fbd626b8ee73e","qa_group_id":"QAG:93e3c9031ca17f2060a5ba1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In our study, we established a biobank of genetically distinct hum... |
QA:244603c62af911650ec7b304 | QAG:828005a31dee0b82f93ba6c9 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Previous studies have reported increased chemoresistance of primary human PDAC cells in the presence of unmatched stromal cells in 3D tumor spheroid and bioengineered models"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated prov... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0a41c8b59dfc878e19639748","quotes":["Previous studies have reported enhanced chemoresistance of primary human PDA... | [
"CLM:0a41c8b59dfc878e19639748",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC9588250"
] | [
"SPAN:779ef9cf16dd080d129b548c"
] | [] | [] | {"qa_id":"QA:244603c62af911650ec7b304","qa_group_id":"QAG:828005a31dee0b82f93ba6c9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Previous studies have reported increased chemoresistance of primar... |
QA:25bc571f124da07e1f93f678 | QAG:6f9ac5bf674b8b13edfdf801 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "A - C PDAC patients in Cohort1# received post-operative chemotherapeutic regimen of gemcitabine/nab-paclitaxel"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with p... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f1dd099f7abd946dd33c3811","quotes":["A - C PDAC patients in Cohort1# received post-operative chemotherapeutic reg... | [
"CLM:f1dd099f7abd946dd33c3811",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:61ef980d828f38a1a68ef03a"
] | [] | [] | {"qa_id":"QA:25bc571f124da07e1f93f678","qa_group_id":"QAG:6f9ac5bf674b8b13edfdf801","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"A - C PDAC patients in Cohort1# received post-operative chemothera... |
QA:26e52754ba229ce44f02574a | QAG:2b7c9da7dca836be663e29b5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Gemcitabine promoted epithelial-mesenchymal transition-like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal-like phenotype"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: retu... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f0f164071a6a41d02d008080","quotes":["41. El Amrani M, et al. Gemcitabine-induced epithelial-mesenchymal transitio... | [
"CLM:f0f164071a6a41d02d008080",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMCID:PMC10709344"
] | [
"SPAN:b70a6bf62437544e257d725e"
] | [] | [] | {"qa_id":"QA:26e52754ba229ce44f02574a","qa_group_id":"QAG:2b7c9da7dca836be663e29b5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Gemcitabine promoted epithelial-mesenchymal transition-like change... |
QA:288c330384469147942ded60 | QAG:28ce2ef6d8b10c490ed87312 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "use optimal metabolic imaging (OMI), a novel and non-destructive imaging tool, to quantify drug promoted changes in cellular metabolism in order to evaluate the effect of several anti-cancer treatments on PDAC organoids"? Return the original wording with paper, Claim, ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:04370c21ee42323f87a07bc7","quotes":["Walsh et al. [ 83 ] use optimal metabolic imaging (... | [
"CLM:04370c21ee42323f87a07bc7",
"CLM:0595c56a1ea6580a9230d904",
"CLM:02502f6c3387b5164c85daf1"
] | [
"PMCID:PMC6906216",
"PMCID:PMC10377599"
] | [
"SPAN:7dfd72c7928f9c9c04e468bb",
"SPAN:6298eeccbe1a49d476af9748"
] | [
"ASC2:4eb5582dc9ece05286ff69ea"
] | [
"HYP:DCH:a25a95d24463d39dc4f40ea3"
] | {"qa_id":"QA:288c330384469147942ded60","qa_group_id":"QAG:28ce2ef6d8b10c490ed87312","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"use optimal metabolic imaging (OMI), a novel and non-destructive i... |
QA:2b2ad299a110a70c2b662c3b | QAG:b2aa8b411e3e69230f10b3d5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Although conventional cell models have substantially led to the current understanding of pancreatic cancer biology and treatment, a link connecting cell cultures and their clinical applications is absent ( 6 )"? Return the original wording with paper, Claim, and Eviden... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:26cc0cdc955f9a1c317e9627","quotes":["Although conventional cell models have substantially contributed to the curr... | [
"CLM:26cc0cdc955f9a1c317e9627",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMCID:PMC6753223"
] | [
"SPAN:5276ba320c031b636a9fc8d1"
] | [] | [] | {"qa_id":"QA:2b2ad299a110a70c2b662c3b","qa_group_id":"QAG:b2aa8b411e3e69230f10b3d5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Although conventional cell models have substantially led to the cu... |
QA:30c194d2a2b11bee319531e8 | QAG:e2b1761088f91f8f765094c1 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "However, despite intensive efforts to provide oncogene and tumor suppressor mutational and transcriptional maps, PDAC prognosis has not been improved for the past 30 years with 5-year survival still below 10%"? Return the original wording with paper, Claim, and Evidenc... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6157af82f80c921ff275d25b","quotes":["However, despite intensive efforts to provide oncogene and tumor suppressor ... | [
"CLM:6157af82f80c921ff275d25b",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC7598647"
] | [
"SPAN:32ad70000c4c9252d2189cb2"
] | [] | [] | {"qa_id":"QA:30c194d2a2b11bee319531e8","qa_group_id":"QAG:e2b1761088f91f8f765094c1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"However, despite intensive efforts to provide oncogene and tumor s... |
QA:323225555f1c0b2e68db7868 | QAG:cf0084708c9c792a0c8589fe | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "We find that missense- but not frameshift mutations in the PDAC driver gene ARID1A was associated with increased sensitivity to the kinase inhibitors dasatinib (p in vitro and in vivo"? Return the original wording with paper, Claim, and Evidence Span references.
Integ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:590d0b3254d077df12e5604c","quotes":["We find that missense- but not frameshift mutations... | [
"CLM:590d0b3254d077df12e5604c",
"CLM:065ed27ad3615b0a901fd1b8",
"CLM:6314e337413af655973a0780"
] | [
"PMCID:PMC7612395",
"PMCID:PMC9289822"
] | [
"SPAN:a7c0ea7a0ac44d765160743f",
"SPAN:125037a602c041b856e1c871"
] | [
"ASC2:8b28f8974b3c8a76b431da4a"
] | [] | {"qa_id":"QA:323225555f1c0b2e68db7868","qa_group_id":"QAG:cf0084708c9c792a0c8589fe","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"We find that missense- but not frameshift mutations in the PDAC dr... |
QA:32ea436e9e1d3722eee32a26 | QAG:12040c9c5970496fb8871716 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "CNVs present in the initial wedge biopsy appear to be rare among PDAC related core pathways, although it is important to note the identified amplification in ERBB2, which led to targeted therapy selection using Trastuzumab, to which the patient did not respond"? Return... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7c56a64c5f50f28bffd5025a","quotes":["CNVs present in the initia... | [
"CLM:7c56a64c5f50f28bffd5025a",
"CLM:0318813e4f6821e1817a7015",
"CLM:27648904a4bd7a4d4eb6217a",
"CLM:4e00ccc75b189b64be71e345"
] | [
"PMCID:PMC5871077",
"PMCID:PMC8134568",
"PMCID:PMC9903715"
] | [
"SPAN:daa3a23aac153a5354163767",
"SPAN:980bcf6c3bf51ffd1d97f4e5",
"SPAN:f793b84bca9d16a452a4f725"
] | [
"ASC2:a494d413797c9b32c2372006",
"ASC2:75e87c5f0ca7abd2a3b0a748"
] | [
"HYP:DCH:4eeb86d2c00c42c09760fdad",
"HYP:DCH:1d9772c0ea8e3593b6c12146"
] | {"qa_id":"QA:32ea436e9e1d3722eee32a26","qa_group_id":"QAG:12040c9c5970496fb8871716","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"CNVs present in the initial wedge biopsy appear to be rare among P... |
QA:3474c8dc2d10e7450d00c9c8 | QAG:2a8c4db31968be80dc476997 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "These invasive features are on one hand, intrinsically imprinted or can be promoted by external stress factors such as chemotherapy 29 , 30"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the ex... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:db61b974e9e0ecafe5be1f6e","quotes":["These invasive features are on one hand, intrinsically imprinted or can be p... | [
"CLM:db61b974e9e0ecafe5be1f6e",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMCID:PMC10709344"
] | [
"SPAN:662721116ae8aa35a00c236e",
"SPAN:f4b294f03abb62640e36befb"
] | [] | [] | {"qa_id":"QA:3474c8dc2d10e7450d00c9c8","qa_group_id":"QAG:2a8c4db31968be80dc476997","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"These invasive features are on one hand, intrinsically imprinted o... |
QA:3599443cbc288e94277f9963 | QAG:e38d9e9b35f8efe3756bc6e0 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Altogether, our study demonstrates increased chemoresistance of PDAC organoids in co-culture with patient-matched CAFs, emphasizing the relevance of complex co-culture models for personalized medicine applications"? Return the original wording with paper, Claim, and Ev... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f4d5294ed1b6567bea6fcedb","quotes":["Altogether, our study demonstrates increased chemoresistance of PDAC organoi... | [
"CLM:f4d5294ed1b6567bea6fcedb",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC9588250"
] | [
"SPAN:08b27b47b8c14f62b0c86929"
] | [] | [] | {"qa_id":"QA:3599443cbc288e94277f9963","qa_group_id":"QAG:e38d9e9b35f8efe3756bc6e0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Altogether, our study demonstrates increased chemoresistance of PD... |
QA:3bb0e0983f7051b4ed7d9a98 | QAG:7d97d10b0f351976b140b48a | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7901605? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC7901605","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC7901605"
] | [] | [] | [] | {"qa_id":"QA:3bb0e0983f7051b4ed7d9a98","qa_group_id":"QAG:7d97d10b0f351976b140b48a","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC7901605... |
QA:40637d270ad39d05cde03850 | QAG:9226705388fe88261d5b7cad | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Although patients with PDAC received combination drug treatments, determining response to drug combinations in culture is a challenging task because of factors such as drug dosing, length of treatment, and the order of administration"? Return the original wording with ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1faa0fc787387878eeec3f23","quotes":["Although patients with PDAC received combination drug treatments, determinin... | [
"CLM:1faa0fc787387878eeec3f23",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC7710298"
] | [
"SPAN:ff5b2b6a1da15b528fe7f01a"
] | [] | [] | {"qa_id":"QA:40637d270ad39d05cde03850","qa_group_id":"QAG:9226705388fe88261d5b7cad","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Although patients with PDAC received combination drug treatments, ... |
QA:40be5aced58e12d43359d263 | QAG:7c3ef6abd23b583bd85f6407 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In pancreatic cancer, CA19-9, a carbohydrate antigen, is known to promote activation of EGFR signaling and induce a pancreatitis phenotype and when combined with Kras G12D led to the development of pancreatic cancer ( 11 ), demonstrating glycosylation changes are not j... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0318813e4f6821e1817a7015","quotes":["In pancreatic cancer, CA19-9, a carbohydrate antigen, is known to promote ac... | [
"CLM:0318813e4f6821e1817a7015",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMCID:PMC7710298"
] | [
"SPAN:9b34bf9772aa1e6a5eeccb35"
] | [] | [] | {"qa_id":"QA:40be5aced58e12d43359d263","qa_group_id":"QAG:7c3ef6abd23b583bd85f6407","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In pancreatic cancer, CA19-9, a carbohydrate antigen, is known to ... |
QA:4dfcd12a7397b11ff4d87120 | QAG:bcbf2c12ba06c112435323d9 | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:33638919? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable an... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMID:33638919","verdict":"no_released_traceable_claim","reason":"No Cla... | [] | [
"PMID:33638919"
] | [] | [] | [] | {"qa_id":"QA:4dfcd12a7397b11ff4d87120","qa_group_id":"QAG:bcbf2c12ba06c112435323d9","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMID:33638919? E... |
QA:4e67895ffff1a863ad4cf45b | QAG:410cb36dbce39f1658ed56bb | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In this cohort, 21 PDAC patients received irbesartan treatment during chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Sp... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:daa6e6c66efec1408bc88fef","quotes":["In this cohort, 21 PDAC patients received irbesartan treatment during chemot... | [
"CLM:daa6e6c66efec1408bc88fef",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:11306cc8d2bf0349cca59533"
] | [] | [] | {"qa_id":"QA:4e67895ffff1a863ad4cf45b","qa_group_id":"QAG:410cb36dbce39f1658ed56bb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In this cohort, 21 PDAC patients received irbesartan treatment dur... |
QA:51c96cca79c591fb1b3872a3 | QAG:0ea184521ca375849970c421 | provenance_qa | paper_evidence_availability | provenance_qa | G021 | en | train | Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8463670? Explicitly abstain if it does not.
Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable... | {"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC8463670","verdict":"no_released_traceable_claim","reason":"No ... | [] | [
"PMCID:PMC8463670"
] | [] | [] | [] | {"qa_id":"QA:51c96cca79c591fb1b3872a3","qa_group_id":"QAG:0ea184521ca375849970c421","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G021","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC8463670... |
QA:546da68dec8053fced89f089 | QAG:59a0bc4b838713d1442ae2e4 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In addition, another recent study has analyzed the expression profiles of the distinct molecular subtypes of human PDAC from the TCGA database and found that tumors of the basal-like/squamous subtype exhibited increased expression of genes that are known to be associat... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4c095462ea9eb2221d8ffbb3","quotes":["In addition, another recent study has analyzed the expression profiles of th... | [
"CLM:4c095462ea9eb2221d8ffbb3",
"CLM:065ed27ad3615b0a901fd1b8"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:da8f9cd09084b83ce4030a20"
] | [] | [] | {"qa_id":"QA:546da68dec8053fced89f089","qa_group_id":"QAG:59a0bc4b838713d1442ae2e4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In addition, another recent study has analyzed the expression prof... |
QA:58197bf95392ab742e6589fa | QAG:0852aa11a58c09c7ec777614 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Pancreatic cancer is a highly lethal established of digestive malignancy that poses significant health risks to individuals worldwide"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact su... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e6d2a45784a7840724f2cb58","quotes":["Pancreatic cancer is a highly lethal form of digestive malignancy that poses... | [
"CLM:e6d2a45784a7840724f2cb58",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMID:37694339"
] | [
"SPAN:29e6904e89d52a30e695870e"
] | [] | [] | {"qa_id":"QA:58197bf95392ab742e6589fa","qa_group_id":"QAG:0852aa11a58c09c7ec777614","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Pancreatic cancer is a highly lethal established of digestive mali... |
QA:620f36e3dc543ce6275957ac | QAG:004841b1857ea91902869f3d | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "The identification of germline alterations in BRCA1/2 and PALB2 in a subset of PDAC patients, causing homologous repair deficiency (HRD), has recently led to the clinical approval of PARP inhibitors, representing the first targeted therapy for HRD-pancreatic cancer"? R... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1209dc20c3fe928b6197659c","quotes":["The identification of germline alterations in BRCA1/2 and PALB2 in a subset ... | [
"CLM:1209dc20c3fe928b6197659c",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC9903715"
] | [
"SPAN:bc8404a93f8b6fe112947d17"
] | [] | [] | {"qa_id":"QA:620f36e3dc543ce6275957ac","qa_group_id":"QAG:004841b1857ea91902869f3d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"The identification of germline alterations in BRCA1/2 and PALB2 in... |
QA:64a62952ae4266a1b89bb279 | QAG:bd53398accfe624473c8f2b5 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "A , B Cell death of PDAC organoids induced by gemcitabine, 5-FU and paclitaxel was decreased when co-cultured with CAFs"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passa... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e0a45ffbc060665ce2c5b983","quotes":["A , B Cell death of PDAC organoids induced by gemcitabine, 5-FU and paclitax... | [
"CLM:e0a45ffbc060665ce2c5b983",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC9588250"
] | [
"SPAN:4dbab276e46ce62231a5470e"
] | [] | [] | {"qa_id":"QA:64a62952ae4266a1b89bb279","qa_group_id":"QAG:bd53398accfe624473c8f2b5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"A , B Cell death of PDAC organoids induced by gemcitabine, 5-FU an... |
QA:64a6b55b481c0966a2d333f6 | QAG:f7b61ddc25b36ba0a048f0cc | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Moreover, compared to the monotherapies, the combined regimen decreased the immunofluorescence intensity of Ki67 staining, which indicated synergistic inhibition of PDAC cell proliferation in PDO models (Fig. S 2 E-F)"? Return the original wording with paper, Claim, an... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:cdc583103d8216cc54cff571","quotes":["Moreover, compared to the monotherapies, the combin... | [
"CLM:cdc583103d8216cc54cff571",
"CLM:065ed27ad3615b0a901fd1b8",
"CLM:fecc7bb8f9e9fc8e693bfc4a"
] | [
"PMCID:PMC10157938",
"PMCID:PMC9357072"
] | [
"SPAN:1d5614b4ae3d8def2d3c68da",
"SPAN:6e64547a3d6f2215d2b8e892"
] | [
"ASC2:1d4d9648defac925e67d4f44"
] | [
"HYP:DCH:fff639fe9f81987d43a45c4c"
] | {"qa_id":"QA:64a6b55b481c0966a2d333f6","qa_group_id":"QAG:f7b61ddc25b36ba0a048f0cc","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Moreover, compared to the monotherapies, the combined regimen decr... |
QA:64b81e017d28d0f5a57825e4 | QAG:1f21113e9ceda47ff16354cb | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "described an overall success rate of expanding PDTOs from PDAC to drug screening of 63%, but this was reduced to 27% when using percutaneous needle biopsies from primary tumors (despite using larger 16–18 G needles), suggesting that PDTO establishment from the primary ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e66675bad0d416a03837469c","quotes":["Likewise, Beutel et al. [ 5 ] described an overall success rate of expanding... | [
"CLM:e66675bad0d416a03837469c",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC10377599"
] | [
"SPAN:9c917e939809b013cb4dff33"
] | [] | [] | {"qa_id":"QA:64b81e017d28d0f5a57825e4","qa_group_id":"QAG:1f21113e9ceda47ff16354cb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"described an overall success rate of expanding PDTOs from PDAC to ... |
QA:65c021f1f830a9011253c9d7 | QAG:0e32c23a114d3bbe005e4374 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "These protocols included directly testing the survival of these organoid cultures when exposed to clinically relevant chemotherapeutic agents, a process we have called pharmacotyping"? Return the original wording with paper, Claim, and Evidence Span references.
Integr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d35e17289648922070470323","quotes":["These protocols include directly testing the survival of these organoid cult... | [
"CLM:d35e17289648922070470323",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMID:29736724"
] | [
"SPAN:b7f916281e9e0df8e0a165f7"
] | [] | [] | {"qa_id":"QA:65c021f1f830a9011253c9d7","qa_group_id":"QAG:0e32c23a114d3bbe005e4374","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"These protocols included directly testing the survival of these or... |
QA:66428785466a24dcfde9a93b | QAG:966fdeac019c27c5720cd697 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "4 Unfortunately, KRASG12C mutants represent only 1% of KRAS mutations in PDAC, 5 while for the most frequent amino acid substitutions G12D (41%), G12V (34%), and G12R (16%) targeted inhibitors have not yet achieved the clinic"? Return the original wording with paper, C... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4e00ccc75b189b64be71e345","quotes":["4 Unfortunately, KRASG12C ... | [
"CLM:4e00ccc75b189b64be71e345",
"CLM:0595c56a1ea6580a9230d904",
"CLM:27648904a4bd7a4d4eb6217a",
"CLM:9bdbcdd17f08cdc31ff7ea78"
] | [
"PMCID:PMC9903715",
"PMCID:PMC8134568",
"PMCID:PMC10060271"
] | [
"SPAN:f793b84bca9d16a452a4f725",
"SPAN:980bcf6c3bf51ffd1d97f4e5",
"SPAN:178c0c5e9e75eb3cc5910ded"
] | [
"ASC2:75e87c5f0ca7abd2a3b0a748",
"ASC2:457825045f85ad164738c9e7"
] | [
"HYP:DCH:1d1f6e43dffdbe3c830ededf",
"HYP:DCH:ed43080ad7497928631a639b"
] | {"qa_id":"QA:66428785466a24dcfde9a93b","qa_group_id":"QAG:966fdeac019c27c5720cd697","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"4 Unfortunately, KRASG12C mutants represent only 1% of KRAS mutati... |
QA:68c332a3143c0e058866694e | QAG:64ea01214076c625ac81fd1d | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "afatinib or pertuzumab) in patients with KRAS wt and NRG1 fusion PDAC, have led to promising initial responses 14"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage wit... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:27648904a4bd7a4d4eb6217a","quotes":["Targeted therapies to inhibit RTKs, ERBB1/EGFR (e.g... | [
"CLM:27648904a4bd7a4d4eb6217a",
"CLM:0595c56a1ea6580a9230d904",
"CLM:4e00ccc75b189b64be71e345",
"CLM:9bdbcdd17f08cdc31ff7ea78"
] | [
"PMCID:PMC8134568",
"PMCID:PMC9903715",
"PMCID:PMC10060271"
] | [
"SPAN:980bcf6c3bf51ffd1d97f4e5",
"SPAN:f793b84bca9d16a452a4f725",
"SPAN:178c0c5e9e75eb3cc5910ded"
] | [
"ASC2:75e87c5f0ca7abd2a3b0a748",
"ASC2:457825045f85ad164738c9e7"
] | [
"HYP:DCH:deda4008cad643925809e0c0"
] | {"qa_id":"QA:68c332a3143c0e058866694e","qa_group_id":"QAG:64ea01214076c625ac81fd1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"afatinib or pertuzumab) in patients with KRAS wt and NRG1 fusion P... |
QA:68f80cc3aa67b89a7389400a | QAG:2e8b68e25918b068e87e511a | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "This study aims to evaluate the feasibility of patient-derived organoid (PDO) and CAF cultures by using single-pass endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) samples from prospectively enrolled pancreatic cancer patients"? Return the original wording wi... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31ea4d3f996a9f8a13dda8dd","quotes":["This study aimed to evaluate the feasibility of pat... | [
"CLM:31ea4d3f996a9f8a13dda8dd",
"CLM:0073e43d7fb8ff1117fb197c",
"CLM:1cf82814939fd48700815c27"
] | [
"PMID:37522250",
"PMCID:PMC9357115"
] | [
"SPAN:ccff93b9869631e2a94401f7",
"SPAN:dae841fb9fb9077e95580248"
] | [
"ASC2:47488a61a5318b0f016c9d24"
] | [
"HYP:DCH:68a2d2b0a03ef175c38ecf20"
] | {"qa_id":"QA:68f80cc3aa67b89a7389400a","qa_group_id":"QAG:2e8b68e25918b068e87e511a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"This study aims to evaluate the feasibility of patient-derived org... |
QA:6a6b4b0a1d5cdb7de2e26de7 | QAG:efe69dfc2cc9b495163f0383 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "The patient-derived organoids (PDO) platform retained the phenotype, genotype, and molecular characteristics of primary tumors"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supportin... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:1cf82814939fd48700815c27","quotes":["The patient-derived organoids (PDO) platform recapi... | [
"CLM:1cf82814939fd48700815c27",
"CLM:0073e43d7fb8ff1117fb197c",
"CLM:0595c56a1ea6580a9230d904"
] | [
"PMCID:PMC9357115",
"PMCID:PMC10157938"
] | [
"SPAN:dae841fb9fb9077e95580248",
"SPAN:4766ce43dd867a0a3a6b4124"
] | [
"ASC2:24db33ab76102b011323e712"
] | [] | {"qa_id":"QA:6a6b4b0a1d5cdb7de2e26de7","qa_group_id":"QAG:efe69dfc2cc9b495163f0383","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"The patient-derived organoids (PDO) platform retained the phenotyp... |
QA:6a893d911fb261c66ce04e7a | QAG:8f211cdc89cb84f6c2589794 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Pancreatic cancer is a highly lethal form of digestive malignancy that affected significant health risks to individuals worldwide"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact suppor... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:89dbd9eb80d2dc48b50f706a","quotes":["Pancreatic cancer is a highly lethal form of digestive malignancy that poses... | [
"CLM:89dbd9eb80d2dc48b50f706a",
"CLM:0073e43d7fb8ff1117fb197c"
] | [
"PMID:37694339"
] | [
"SPAN:29e6904e89d52a30e695870e"
] | [] | [] | {"qa_id":"QA:6a893d911fb261c66ce04e7a","qa_group_id":"QAG:8f211cdc89cb84f6c2589794","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Pancreatic cancer is a highly lethal form of digestive malignancy ... |
QA:7206cb4e8c83a319de4599eb | QAG:c98c58e1bbe539647feaeeb3 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "High-throughput drug screening with a panel of 1304 FDA-approved drugs identified several compounds that effectively decreased GEM chemoresistance in PDAC in organoid cultures"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated pr... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:48c63c07ec6922389d8f68f8","quotes":["High-throughput drug screening with a panel of 1304... | [
"CLM:48c63c07ec6922389d8f68f8",
"CLM:0318813e4f6821e1817a7015",
"CLM:4cda3fb211dad38b1cb55ea2",
"CLM:251c4a58d8be4691cf9dce11",
"CLM:bdc47ee128bed46c88809384"
] | [
"PMCID:PMC10157938",
"PMCID:PMC9645660",
"PMCID:PMC6525827"
] | [
"SPAN:09c4b4174e3289dceed43948",
"SPAN:b46aa9c3e528dc03aaf3c013",
"SPAN:0810c5320b2ce055856c748e",
"SPAN:71312f60dc1686dba71e33a9"
] | [
"ASC2:85d16d90b838b8ef5d3c5959",
"ASC2:e460df608e6207f60e9fcf20"
] | [
"HYP:DCH:31603103e518cbb1dbf7a252"
] | {"qa_id":"QA:7206cb4e8c83a319de4599eb","qa_group_id":"QAG:c98c58e1bbe539647feaeeb3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"High-throughput drug screening with a panel of 1304 FDA-approved d... |
QA:720c8c6fc04e7ed030da40a8 | QAG:8c37accd0e3e08d82b2a947b | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "C-H Organoids received vehicle, GEM (0.8 μM), irbesartan (1 μM) and GEM (0.8 μM) plus irbesartan (1 μM), followed by continually monitoring PDAC organoid apoptosis by real-time caspase3/7 probe imaging for 72 h"? Return the original wording with paper, Claim, and Evide... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eec99ecfaa1a1af391b1a038","quotes":["C-H Organoids were treated with vehicle, GEM (0.8 μM), irbesartan (1 μM) and... | [
"CLM:eec99ecfaa1a1af391b1a038",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:372ab7089b0bc7c3ed58976a"
] | [] | [] | {"qa_id":"QA:720c8c6fc04e7ed030da40a8","qa_group_id":"QAG:8c37accd0e3e08d82b2a947b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"C-H Organoids received vehicle, GEM (0.8 μM), irbesartan (1 μM) an... |
QA:7238e6a75b7723a2cdb6bfac | QAG:1ed5e708fb7c654eb8f8cf8a | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "In our gemcitabine dose-response experiment, we observed that PDAC organoid circularity and solidity decreased with an increase in gemcitabine dosage"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: ret... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e27ebd080dc465057b559b9d","quotes":["In our gemcitabine dose-response experiment, we observed that PDAC organoid ... | [
"CLM:e27ebd080dc465057b559b9d",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC9645660"
] | [
"SPAN:2ec78ecbdf5bcfdbd84d1d87"
] | [] | [] | {"qa_id":"QA:7238e6a75b7723a2cdb6bfac","qa_group_id":"QAG:1ed5e708fb7c654eb8f8cf8a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"In our gemcitabine dose-response experiment, we observed that PDAC... |
QA:742d5740869b5a26ecbafc49 | QAG:f2ac9b5e967cdd5a8732a086 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Several studies aims to evaluate patient-derived organoids as predictive platforms for the choice of chemotherapy regimens and entirely novel drugs and combinations for the treatment of PDAC"? Return the original wording with paper, Claim, and Evidence Span references.... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5ee162caed19a92db3c51f68","quotes":["Several studies aim to evaluate patient-derived organoids as predictive plat... | [
"CLM:5ee162caed19a92db3c51f68",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10046065"
] | [
"SPAN:45f42fac1481eb14e44681d5"
] | [] | [] | {"qa_id":"QA:742d5740869b5a26ecbafc49","qa_group_id":"QAG:f2ac9b5e967cdd5a8732a086","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Several studies aims to evaluate patient-derived organoids as pred... |
QA:787cf7040f700c6168a93802 | QAG:64de5c2386ecc515a8fde3b7 | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "Additionally, we collected needle biopsy PDAC tissue samples from 104 patients with advanced PDAC in Cohort2# who had received GEM plus nab-paclitaxel chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance req... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a8197d3c6b02fa6d56824623","quotes":["Additionally, we collected needle biopsy PDAC tissue samples from 104 patien... | [
"CLM:a8197d3c6b02fa6d56824623",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:d67a3ac04c28ae1b887a0a12"
] | [] | [] | {"qa_id":"QA:787cf7040f700c6168a93802","qa_group_id":"QAG:64de5c2386ecc515a8fde3b7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"Additionally, we collected needle biopsy PDAC tissue samples from ... |
QA:7d8590f210fcffaf1f707a01 | QAG:acf3fa352e4ed0c0353143de | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "9 A-C, the results of apoptosis assays and CCK8 assays in these PDX cell lines showed that simultaneous depletion of stemness genes (SOX9/SOX2/OCT4) and iron metabolism genes (FTH1/FTL/TFRC) all together could fully abrogate the GEM resistance of PDAC promoted by c-Jun... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6527f79c8b31320de6d5f529","quotes":["As shown in Fig. 9 A-C, the results of apoptosis assays and CCK8 assays in t... | [
"CLM:6527f79c8b31320de6d5f529",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:a3d5ae0256e82f67e693a853"
] | [] | [] | {"qa_id":"QA:7d8590f210fcffaf1f707a01","qa_group_id":"QAG:acf3fa352e4ed0c0353143de","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"9 A-C, the results of apoptosis assays and CCK8 assays in these PD... |
QA:7e7ed8a9774e57a89ee5865d | QAG:f3836b7cc83aa3b79f4c836f | provenance_qa | exact_evidence_retrieval | provenance_qa | G021 | en | train | Which exact source passage supports the statement "10 Irbesartan inhibited cancer stemness and iron metabolism in PDAC"? Return the original wording with paper, Claim, and Evidence Span references.
Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; ... | {"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d5f9cb171171f015f56cf38c","quotes":["Fig. 10 Irbesartan significantly suppressed cancer stemness and iron metabol... | [
"CLM:d5f9cb171171f015f56cf38c",
"CLM:0318813e4f6821e1817a7015"
] | [
"PMCID:PMC10157938"
] | [
"SPAN:35692b70e40abd51d6d07595"
] | [] | [] | {"qa_id":"QA:7e7ed8a9774e57a89ee5865d","qa_group_id":"QAG:f3836b7cc83aa3b79f4c836f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G021","question":"Which exact source passage supports the statement \"10 Irbesartan inhibited cancer stemness and iron metabolism in PDA... |
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