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Over the last seven years our laboratory has focused on the determination of the structural aspects of nucleoside triphosphate diphosphohydrolases (NTPDases) using site-directed mutagenesis and computational comparative protein modeling to generate hypotheses and models for the hydrolytic site and enzymatic mechanism o...
Natural allergen sources can supply large quantities of authentic allergen mixtures for use as immunotherapeutics. However, such extracts are complex, difficult to define, vary from batch to batch, which may lead to unpredictable efficacy and/or unacceptable levels of side effects. The use of recombinant expression sys...
The HIV-1 nucleocapsid is formed during protease (PR)-directed viral maturation, and is transformed into pre-integration complexes following reverse transcription in the cytoplasm of the infected cell. Here, we report a detailed transmission electron microscopy analysis of the impact of HIV-1 PR and reverse transcripta...
Optimization of a serotype-selective, small-molecule inhibitor of botulinum neurotoxin serotype A (BoNTA) endopeptidase is a formidable challenge because the enzyme-substrate interface is unusually large and the endopeptidase itself is a large, zinc-binding protein with a complex fold that is difficult to simulate comp...
Many biological databases that provide comparative genomics information and tools are now available on the internet. While certainly quite useful, to our knowledge none of the existing databases combine results from multiple comparative genomics methods with manually curated information from the literature. Here we des...
Mucopolysaccharidosis (MPS) IIIB (Sanfilippo Syndrome type B) is caused by a deficiency in the lysosomal enzyme N-acetyl-glucosaminidase (Naglu). Children with MPS IIIB develop disturbances of sleep, activity levels, coordination, vision, hearing, and mental functioning culminating in early death. The murine model of M...
Duchenne Muscular Dystrophy (DMD) is a severe muscle degenerative disease, due to absence of dystrophin. There is currently no effective treatment for DMD. Our aim is to up-regulate the expression level of the dystrophin related gene utrophin in DMD, complementing in this way the lack of dystrophin functions. To this e...
Although it is acknowledged that genetic variation contributes to individual differences in thermotolerance, the specific genes and pathways involved and how they are modulated by the environment remain poorly understood. We link natural variation in the thermotolerance of neural function and behavior in Drosophila mel...
Hormone level differences are generally accepted as the primary cause for sexual dimorphism in animal and human development. Levels of low molecular weight metabolites also differ between men and women in circulating amino acids, lipids and carbohydrates and within brain tissue. While investigating the metabolism of bl...
To evaluate the effects of resistant starch, fat, and protein on rates of starch hydrolysis in vitro.
To investigate the effect of complementary food supplements with protein and multi-micronutrients on respiratory infections and diarrhea of infants and yound children in poor rural China.
To evaluate the effects of taurine on the expression of tumor necrosis factor-alpha (TNF-alpha) protein of lung in rats treated by silica.
Microcystins (MCs) may be group of closely related toxic cyclic heptapeptides produced by common cyanobacteria (blue-green algae). Their toxicity could be associated with specific inhibition of intracellular protein phosphatases type-1 and type-2A (PP1 and PP2A, respectively). There are some methods for analyzing and d...
To identify the type of the intermediate filament (IF) protein of Angiostrongylus cantonensis and analyze its tissue localization.
To construct and identify recombinant adenovirus Ad-SHP1 carrying human SH2 domain-containing protein tyrosine phosphatase (SHP-1).
To construct the eucaryotic recombinant plasmid of pYES2/LactoferricinB expressing in yeast of S. cerevisiae, of which the expressed protein antibacterial activity was verified in preliminary.
To investigate the expression of fusion protein c-Abeta-c, a fusion protein from the beta amyloid peptide (Abeta) and the Hepatitis B core antigen/ Major immunodominant region (HbcAg/MIR), in the BL21/pET28 prokaryotic expression system and to immunize mice with the expressed fusion protein and evaluate the immunogenic...
A central event in Alzheimer's disease (AD) is the regulated intramembraneous proteolysis of the beta-amyloid precursor protein (APP), to generate the beta-amyloid (Abeta) peptide and the APP intracellular domain (AICD). Abeta is the major component of amyloid plaques and AICD displays transcriptional activation proper...
The human NAD+-dependent protein deacetylase SIRT2 resides predominantly in the cytoplasm where it functions as a tubulin deacetylase. Here we report that SIRT2 maintains a largely cytoplasmic localization during interphase by active nuclear export in a Crm1-dependent manner. We identified a functional, leptomycin B-se...
The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative bacteria and forms part of the innate immune response in mammals. Like other class 1 receptors, TLR4 ...
Variation in gene content among strains of a bacterial species contributes to biomedically relevant differences in phenotypes such as virulence and antimicrobial resistance. Group A Streptococcus (GAS) causes a diverse array of human infections and sequelae, and exhibits a complex pathogenic behavior. To enhance our un...
Gene array analysis has been widely used to identify genes induced during T cell activation. Our studies identified an immediate early gene that is strongly induced in response to IL-2 in mouse T cells which we named cysteine- serine-rich nuclear protein-1 (CSRNP-1). The human ortholog was previously identified as an A...
Social insects rely heavily on pheromone communication to maintain their sociality. Egg protection is one of the most fundamental social behaviours in social insects. The recent discovery of the termite-egg mimicking fungus 'termite-ball' and subsequent studies on termite egg protection behaviour have shown that termit...
Acromegaly is accompanied by increased cardiovascular mortality and a cluster of proatherogenic risk factors. In the general population, ischaemic heart disease (IHD) is associated with elevated levels of inflammatory markers. The acute phase reactant (APR) C-reactive protein (CRP) has been reported to be reduced in ac...
Using pasture and grazed forest-range for a system of producing live-stock by feeding grass alone reduces the inputs of energy about 60 percent and land resources about 8 percent, but also reduces by about half the production of animal protein in the United States. Under a system in which only grass was fed, livestock ...
On an artificial substrate of filter paper, Porcellio scaber cannot extract copper from leaf litter. If one increases the copper content of the food by soaking the leaves in solutions of CuSO(4) or in organic extracts, assimilation of copper becomes possible, but only at concentrations higher than 1 microgram of copper...
We began by pointing out that tools (for example) have size optima that are dictated by function. If we assume that the university has a function, it would seem reasonable to think about the size which will serve that function best. The principle of size optimization is fundamental, but its application to the universit...
Ion implantation, because it is inherently a strongly nonequilibrium process, can add a new dimension to materials studies. A large variety of chemical elements may be readily introduced into a target substrate by ion bombardment at concentrations considerably greater than the normal solid solubilities. In addition, th...
Scanning tunneling microscopy was used to characterize the growth of oxidized areas on galena (100) surfaces and the formation of gold islands by the reductive adsorption of AuCl(4)(-) from aqueous solution. The gold islands and galena substrate were distinguished by atomic resolution imaging and tunneling spectroscopy...
A cloned Drosophila heat shock protein 22 gene was transfected into two independently established Drosophila cell lines. Each line carried a different heat shock protein 22 allele, distinguishable by electrophoresis of the protein. The transfected gene was not expressed at 25 degrees C but could be induced at 36 degree...
Endoreduplication is an endonuclear chromosome duplication that occurs in the absence of mitosis and in Zea mays (L.) is required for endosperm development. Induction of DNA synthesis during early stages of endosperm development is maintained by increasing the amount and activity of S phase-related protein kinases, whi...
A high molecular weight crystalline protein, possessing the properties of ring spot virus and differing markedly from tobacco mosaic virus protein in its physical, chemical and serological properties, has been isolated by means of an ultracentrifuge from Turkish tobacco plants diseased with tobacco ring spot virus. Ult...
As diamond-producing catalysts, 12 transition metals such as iron, cobalt, and nickel were first reported by General Electric researchers more than 30 years ago. Since then, no additional elemental catalyst has been reported. An investigation of the catalytic action of group V elements is of great interest from the vie...
Phosphorylation of several polypeptides in corn coleoptiles was promoted by adding calcium. Chlorpromazine, a calmodulin inhibitor, reduced calcium-promoted phosphorylation, suggesting that the phosphorylation was modulated by calmodulin. This is evidence for the role of calcium in protein phosphorylation in plants and...
Several well-characterized transition metal catalysts contain a metal-carbon double bond or a metal-carbon triple bond. In other homogeneous (or heterogeneous) catalyst systems in which the metal is likely to be in a relatively high oxidation state, such as molybdenum(VI) or tungsten(VI), metal-carbon multiple bonds ma...
The university pays for its benefits from a federally financed project with its own investments in the faculty scientist and not, as is often assumed, by its absorption of project costs that are not reimbursed by the government. An analysis of the exchange of resources between the university, the scientist, the discipl...
A rapid, simple, quantitative technique has been developed for the study of the action of hydrolytic enzymes on certain insoluble substrates. The end point of digestion is indicated by the release of a glass bead, when two pieces of lens paper sealed together by the substrate separate due to its digestion by the enzyme...
The process of polar auxin transport, central to a plant's auxin relations, can be inhibited by a group of synthetic compounds that apparently act by binding to a plasma membrane protein known as the naphthylphthalamic acid (NPA) receptor. No endogenous ligand to the NPA receptor, capable of affecting polar auxin trans...
The abundance of large, previously unknown larvacean feeding structures in the deep ocean is a striking contrast to the rarity of such forms taken in net hauls. In some areas, abandoned houses and their disintegrated parts provide a substrate for other organisms and contribute to organic aggregates.
Either 50 mg 1(-)tryptophane or 1.0 mg nicotinic acid per 100 gms of ration completely counteracts the growth retardation caused by the inclusion of 40 per cent. corn grits in a low protein ration. A possible explanation of this observation is discussed.
Randomization has played an important role in social affairs, going back at least to biblical days. The drawing of lots, one of the simplest forms of randomization, has been used publicly in many different contexts. Although the legal use of randomization techniques and lotteries in the United States dates back at leas...
Phenols are commonly regarded as feeding deterrents for phytophagous insects, but the tree locust Anacridium melanorhodon survives better and grows faster when certain phenols are added to a food plant that is relatively low in both protein and phenols. The phenols are at high concentration in the common host plants. M...
In the report "Lactate dehydrogenase isozymes: Further kinetic studies at high enzyme concentration" by Thomas Wuntsch, Raymond F. Chen, and Elliot S. Vesell [169, 480 (1970)], 14.0 mM NAD in line 2 of the heading of Table 1 should read 14.0 , microM NAD.
Hyper-Rayleigh scattering has been used to determine the nonlinear optical properties of a chromophore-containing protein in solution. Because the technique of hyper-Rayleigh scattering allows the measurement of hyperpolarizabilities in an isotropic solution without the application of an electric field, this method is ...
Sediments of deep Canadian shield lakes have a firm mud-water interface and an intricately structured, oxygenated surface. Surface relief is not uniform, but is broken by small ridges and upright chironomid tubes. The sedimentary material behaves like a weak jelly and becomes flocculent only when violently disturbed. S...
Evidence is presented that the coat protein of bacteriophage f2 causes the lysis of infected Escherichia coli. To lyse bacteria, the coat protein produced must be of the quality to produce phage particles, although it need not be produced in amounts sufficient to give a large yield of particles. Mutants that are blocke...
Replication and the performance of a differentiated function have been considered antagonistic processes. When cells in culture are partially tially synchronized with 5-fluoro-2'-deoxyuridine (FUdR), the synthesis of the specialized protein (collagen) is not reduced during chromosomal replication (S period). Collagen s...
The development of L-tyrosine : 2-oxoglutarate aminotransferase in newborn rats is suppressed by actidione (cycloheximide), an inhibitor of protein biosynthesis, administered immediately after birth.
The mechanism of many organic oxidation and reduction reactions can be described in terms of the formation and reaction of free radicals with metal complexes. Redox (trace-metal) catalysis also involves the oxidation and reduction of radical intermediates with a metal species which oscillates between several oxidation ...
Results are presented for the first time-resolved x-ray absorption measurements with a time resolution of 300 microseconds on a dynamically evolving chemical system. By synchronizing a neodymium: yttrium-aluminum-garnet pulsed laser with the bursts of x-rays emitted from the Cornell High Energy Synchrotron Source, it w...
Certain problems usually associated with the histochemistry of lipases are obviated by a technique that utilizes the endogenous blood chylomicrons and the cellular stores of triglyceride as substrates for the histochemical demonstration of lipolytic enzyme activity in situ. In spreads of mesenteric adipose tissue, the ...
Early dormancy involves a number of phenomena: cessation of active growth, formation of terminal buds, formation of abscission layers in leaves, development of cold resistance, development of winter rest (a chilling requirement), and leaf fall. The buds of some tree species (or some races of a species) have a true rest...
Human spinal fluid is a more favorable medium to further the synthesis of acetylcholine in vitro, using enzyme obtained from frog brain, than is serum. Also, since less acetylcholine was synthesized in the presence of spinal fluid from patients with myasthenia gravis than spinal fluid of control subjects, it is probabl...
Camissonia claviformis, a winter annual of Death Valley, California, that fixes carbon dioxide by the C(3) mechanism, has an in situ photosynthetic rate at midday in spring of nearly 6 nanomoles of carbon dioxide per square centimeter per second-an exceptionally high rate. Camissonia fixes absorbed noon sunlight in the...
Fraction 1 protein has been isolated from leaves of a male sterile Nicotiana tabacum plant containing an extra N. debneyichromosome. The extra chromosome induces appearance of a third polypeptide composing the small subunit of fraction 1 protein, which otherwise contains two polypeptides as is shown by analysis of nume...
Acetic-acid (0.01 molar) extracts of wheat flour contain fibrils of alpha-gliadin which are about 80 angstroms thick and up to several thousand angstroms long. These fibrils dissociate to globular protein subunits at very low ionic strength and low pH. The fibrils can be reformed by increasing the pH to 5.1 and the ion...
Two azaguanine-resistant clones of cultured, human fibroblasts were isolated from unrelated strains of karyotypically normal, male cells. The most resistant mutant has little hypoxanthine-guanine phosphoribosyltransferase activity, is virtually unable to incorporate hypoxanthine (a normal substrate of the enzyme), and ...
Gene fusions were constructed between a yeast expression plasmid and a Cellulomonas fimi DNA fragment encoding an endo-1,4-beta-D-glucanase or carboxymethylcellulase. Yeast transformed with the recombinant plasmids secreted carboxymethylcellulase activity. Secretion of active enzyme was greatly increased when the leade...
The culture of channel catfish, trout, and crayfish is a well-established, profitable enterprise, but aquaculture provides only a fraction of the protein consumed by Americans, who prefer red meat. This situation could change, since pond-raised fish require less energy for protein synthesis than land animals, the suppl...
Detritivores have been thought to derive nutrition from microbes associated with detrital particles and not from the nonliving plant substrate. The polychaete Capitella capitata, however, was found to derive a major portion of its nitrogen from the plant substrate when it feeds on detritus derived from seaweed. Microbe...
Salicin, a toxic phenol glycoside, is used by larvae of the beetle Chrysomela aenicollis as a substrate for producing defensive secretions. In the east-central Sierra Nevada mountains of California, salicin concentrations ranged from 0.05 percent to over 5 percent of dry weight in leaves of different plants of Salix or...
Two improvements are described in the use of shadow electron micrography for the observation of particles of macromolecular dimensions. One involves the substitution of gold for chromium as shadowing metal. The thinner gold film that can be employed gives a truer representation of the shape of particles so small that s...
Examination of the organic matter in some modern and fossil oolites has shown that it contains protein, with a high content of acidic amino acids. Artificial oolites from a water-processing plant contained no amino acids. The protein matrix may influence the formation of natural oolites by concentrating calcium ions.
Four major points emerge from this brief survey of the evidence: 1) The food crisis in 1974 seems to have been largely a result of distributional factors. The per capita availability of food grains from all sources, including imports, although below 1971 and 1972 levels, was probably above the average for 1963 to 1973....
Atomic force microscopy has been used to measure the surface profile of a periodic array of 10-nanometer (nm)-diameter holes fabricated by fast-atom beam milling of a smooth graphite surface in which a 3.5-nm-thick titanium oxide screen was used as a mask. The nanostructured titanium oxide mask was itself derived from ...
In many polymer-metal systems, chemical bonds are formed that involve metal-oxygen-carbon complexes. Infrared and Mössbauer spectroscopic studies indicate that carboxylate groups play an important role in some systems. The oxygen sources may be the polymer, the oxygen present in the oxide on the metal surface, or atmos...
Linear, potato spindle tuber viroid RNA has been used as a substrate for an RNA ligase purified from wheat germ. Linear viroid molecules are efficiently converted to circular molecules (circles) which are indistinguishable by electrophoretic mobility and two-dimensional oligonucleotide pattern from viroid circles extra...
A major component of the Inter-Union Commission on Geodynamics Project, labeled "Internal Properties and Processes," included certain experimental and theoretical research in tectonophysics, seismology, geochemistry, petrology, volcanology, and planetology. This review focuses on a few research areas in which there hav...
The addition of certain sugars to the food consumed during larval development increases the taste sensitivity of adult blowflies to some sugars, decreases it to others, and is without effect on the sensitivity to still others. No correlation with metabolic phenomena is apparent. The hypothesis that repression of induct...
A transplantable plasmacell tumor in mice produces both a gammaM-macroglobulin serum protein with a sedimentation coefficient of 17S and a kappa-type urinary protein. The reduced and alkylated macroglobulin, when examined by electrophoresis in acid-urea polyacrylamide gel, had a fast component which migrated in the sam...
Cotyledons are specialized leaves produced during plant embryogenesis. Cotyledons and leaves typically differ in morphology, ultrastructure, and patterns of gene expression. The leafy cotyledon (Iec) mutant of Arabidopsis thaliana fails to maintain this distinction between embryonic and vegetative patterns of plant dev...
Ani enzyme activity similar to that of dextranase is associated with coleoptiles of Avena sativa. When subjected to purified dextranase, both the pure natural dextran and the cell walls of the Avena coleoptiles yield isomaltose and isomaltotriose. Thus, the cell walls contain dextrans or dextran-like compounds. Coleopt...
Although the aphid Rhopalosiphum padi does not regularly transmit the MAV isolate of barley yellow drawf virus from singly infected oats, it often transmits MAV, together with the serologically unrelated RPV isolate, from plants doubly infected by MAV and RPV. Vector specificity of the virus isolates appears to be a fu...
Crystalline catalase of high purity and activity was prepared from a heme-requiring Staphylococcus aureus mutant, JT/52, grown in the presence of heme. A crystalline protein was obtained from the same cells grown without heme. This enzymatically inactive protein and the catalase cross-react strongly when tested by a va...
The calcium-activated adenosine triphosphatase activity of cultured single beating heart cells of the rat was localized and visualized by incubating the cells, after extraction in a mixture of glycerol and water, with adenosine triphosphate and calcium. The calcium phosphate, precipitated at the site of the enzyme reac...
Sunlight is directly converted to chemical energy in hydrogen-evolving photoelectrochemical cells with semiconductor electrodes. Their Gibbs free energy efficiency of solar-to-hydrogen conversion, 13.3 percent, exceeds the solar-to-fuel conversion efficiency of green plants and approaches the solar-to-electrical conver...
The induction of the male sexual organ primordia (antheridial hyphae) by the steroid hormone antheridiol in the water mold Achlya ambisexualis requires both transcription and translation. Inhibition of either of these processes eliminates the expected increase in the production and release of the enzyme cellulase, whic...
This article discusses circumstances under which free quarks catalyze exothermal nuclear reactions. It also presents possible methods for removing quarks sequestered by nuclear reaction products. Stable quarks that are negatively charged and significantly heavier than electrons attract positively charged nuclei to form...
Microspectrophotometric measurements of DNA, RNA, histone, and total protein in the nuclei of mesophyll cells of Little Club wheat leaves were made at intervals after infection with the stem rust fungus. No change in host DNA was found within 6 days after inoculation, but there were decreases in histones and marked inc...
The growth of small ( approximately 10-micrometer) diamond particles (on 0.1-or 0.25-micrometer seed crystals) using an effusive glow discharge nozzle for H.and a separate supersonic pyrolysis jet for .CH(3) is reported. Laser micro-Raman, scanning electron microscopy, and x-ray photoelectron spectroscopy data are pres...
About 100 pure-bred samples of nine varieties of pulses raised in different state agricultural farms of India in 1957, when analyzed, indicated variations in the protein content of a single variety extending up to 60 percent in some cases, depending upon the strain and the locality where grown.
A major turnabout in the attitude of the Atomic Energy Commission toward the nuclear power industry was signaled last week by the ntew AEC chairman James R. Schlesinger. With patrician froideur, Schlesinger informed a mass gathering of the nuclear power industry at Bal Harbour, Florida, that from henceforth the AEC woL...
Carbon from the Allende meteorite is not graphite but carbyne (triply bonded elemental carbon), inasmuch as on heating to 250 degrees to 330 degrees C it releases mainly triply bonded fragments: -(C identical withC)(n),- with n = 1 to 5, and -(C identical withC)(n)-CN, with n = 1 to 3. Although carbynes have been known...
A circadian rhythm in the activity of luciferase is partly responsible for rhythmic bioluminescence in the dinoflagellate alga Gonyaulax polyedra. The cyclic activity of this enzyme can be attributed to a corresponding rhythm in the concentration of immunologically reactive luciferase protein. Hence protein turnover (s...
A cantilever resonant microbeam, laser diodes, and a photodiode have been fabricated on the surface of a gallium arsenide substrate. The microbeam is excited photothermally by light from a laser diode. The vibration is detected with a photodiode as the variation in light output caused by the difference in optical lengt...
Sequences coding for the bean seed protein phaseolin were inserted into transferred DNA regions of tumor-inducing plasmids. Constructions were devised in which the coding region of phaseolin was fused in the correct reading frame with the coding region of octopine synthase and placed under the transcriptional control o...
A calcium-binding soluble protein extracted from oyster shell suppresses calcium carbonate nucleation and decreases the rate of crystal growth in vitro. These findings suggest that soluble matrix may regulate shell growth.
Resistance to the spore-crystal protein complex of Bacillus thuringiensis, the most widely used and intensively studied microbial insecticide, has been presumed to be unlikely to occur. In this study it was found that Plodia interpunctella, a major lepidopteran pest of stored grain products, can develop resistance to t...
Two-dimensional molecular patterns were obtained by the adsorption of long-chain alkanes, alcohols, fatty acids, and a dialkylbenzene from organic solutions onto the basal plane of graphite. In situ scanning tunneling microscopy (STM) studies revealed that these molecules organize in lamellae with the extended alkyl ch...
The levels enzyme activity given in Table 1 of the report, "Red Cell Glucose-6-Phosphate and 6-Phosphogluconic Dehydrogenases and Nucleoside Phosphorylase," by P. A. Marks [Science 127, 1338 (1958)] are incorrect by a factor of 10(3). All activity levels should read per 10(9), not 10(6), erythrocytes.
Direct catalytic hydration of terminal alkenes to primary alcohols would be an inexpensive route to industrially useful alcohols and a convenient synthetic route for the synthesis of terminal alcohols in general. The reaction between trans- PtHCl(PMe(3))(2) (where Me = CH(3)) and sodium hydroxide in a one-to-one mixtur...
Molecular chaperones are a family of unrelated proteins found in all types of cell. They mediate the correct assembly of other polypeptides, but are not components of the mature assembled structures. Chaperones function by binding specifically to interactive protein surfaces that are exposed transiently during many cel...
1) The development of the maize plant, from germination to the maturation of the seed, is divided into the vegetative, transitional, reproductive, and seed stages. The ear and tassel differentiate and develop in the reproductive stage. 2) The mature tassel is a terminal, staminate inflorescence consisting of a symmetri...
The statistical mechanics of associative memories and spin glasses suggests ways to design Hamiltonians for protein folding. An associative memory Hamiltonian based on hydrophobicity patterns is shown to have a large capacity for recall and to be capable of recognizing tertiary structure for moderately variant sequence...
Hydrofluorocarbons, many of which contain a CF(3) group, are one of the major substitutes for the chlorofluorocarbons and halons that are being phased out because they contribute to stratospheric ozone depletion. It is critical to ensure that CF(3) groups do not cause significant ozone depletion. The rate coefficients ...
On page 925 of the 9 Nov. issue of Science we stated that "Nineteen members of the Atomic Energy Commission research project at the University of Rochester Medical Center" endorsed a statement criticizing the President's recent defense of nuclear weapons tests. Actually, only five of the 19 members of the university st...
YBa(2)Cu(3)O(7) films have been grown epitaxially on SrTiO(3) (100) and LaAlO(3) (100) substrates with nearly pure a-axis orientation and with transition temperature T(c) (R = 0) of 85 K. A unique feature of these films is their smooth surface. These smooth surfaces enable the growth of short-period superlattices with ...
When a small amount of blood serum is dropped into the nose of a guinea pig the serum is absorbed by the mucous membrane and, after a definite period of incubation, the animal can be shown to have become profoundly changed. Depending upon the number of instillations, the interval between them and, especially, the quant...
Colloidal platinum was prepared and precipitated directly onto photosynthetic thylakoid membranes from aqueous solution and entrapped on fiberglass filter paper. This composition of matter was capable of sustained simultaneous photoevolution of hydrogen and oxygen when irradiated at any wavelength in the chlorophyll ab...
A method has been developed for the preparation of uniform palladium particles of diameter from 55 to 450 angstroms. Uniform particles of gold layered on palladium were also synthesized. Hydrothermal treatment of aluminum hydroxide sol was used to prepare rods of alumina with uniform cross section from 100 to 500 angst...

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