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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
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int64
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A
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C
C
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A
G
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C
C
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A
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A
G
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A
G
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C
C
C
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C
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C
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A
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C
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C
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A
C
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3,652
A
G
T
C
C
C
T
C
A
A
G
T
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C
A
C
A
G
C
T
C
C
T
T
C
T
A
G
C
A
C
T
T
C
T
G
G
T
G
C
C
A
T
A
T
A
T
C
T
G
A
T
A
G
T
G
C
C
A
A
C
C
T
G
A
A
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1
3,653
C
A
A
A
G
C
T
G
A
T
T
C
A
C
A
G
T
C
C
C
T
C
A
A
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T
T
C
A
C
A
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C
T
C
C
T
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T
A
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A
C
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T
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T
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G
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G
C
C
A
T
A
T
A
T
C
T
G
A
T
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1
3,654
A
T
A
T
A
T
G
G
C
A
C
C
A
G
A
A
G
T
G
C
T
A
G
A
A
G
G
A
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T
G
T
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A
A
C
T
T
G
A
G
G
G
A
C
T
G
T
G
A
A
T
C
A
G
C
T
T
T
G
A
A
A
C
C
0.084149
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0
0
0
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1
3,655
T
A
A
A
T
A
T
C
T
C
C
C
A
A
T
A
G
A
T
T
A
G
T
C
C
A
A
G
A
G
C
A
T
A
C
A
T
G
T
C
T
A
C
T
T
G
T
T
T
C
A
A
A
G
C
T
G
A
T
T
C
A
C
A
G
G
0.09589
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0
0
0
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1
3,656
A
C
A
T
C
T
C
A
T
A
A
A
T
A
T
C
T
C
C
C
A
A
T
A
G
A
T
T
A
G
T
C
C
A
A
G
A
G
C
A
T
A
C
A
T
G
T
C
T
A
C
T
T
G
T
T
T
C
A
A
A
G
C
T
G
T
0.097847
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0
0
0
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1
3,657
A
C
A
T
C
T
C
A
T
A
A
A
T
A
T
C
T
C
C
C
A
A
T
A
G
A
T
T
A
G
T
C
C
A
A
G
A
G
C
A
T
A
C
A
T
G
T
C
T
A
C
T
T
G
T
T
T
C
A
A
A
G
C
T
G
G
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0
0
0
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0.060665
0.043053
1
3,658
C
A
G
T
A
G
T
T
T
T
T
A
C
C
T
G
G
G
A
A
G
A
G
G
T
C
T
G
T
A
C
A
T
C
T
C
A
T
A
A
A
T
A
T
C
T
C
C
C
A
A
T
A
G
A
T
T
A
G
T
C
C
A
A
G
A
0.09002
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0
0
0
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0.043053
0.021526
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0.062622
0.046967
1
3,659
T
T
G
G
A
C
T
A
A
T
C
T
A
T
T
G
G
G
A
G
A
T
A
T
T
T
A
T
G
A
G
A
T
G
T
A
C
A
G
A
C
C
T
C
T
T
C
C
C
A
G
G
T
A
A
A
A
A
C
T
A
C
T
G
T
C
0.09002
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0
0
0
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0.046967
1
3,660
G
A
C
A
G
T
A
G
T
T
T
T
T
A
C
C
T
G
G
G
A
A
G
A
G
G
T
C
T
G
T
A
C
A
T
C
T
C
A
T
A
A
A
T
A
T
C
T
C
C
C
A
A
T
A
G
A
T
T
A
G
T
C
C
A
T
0.088063
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0
0
0
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0.046967
1
3,661
A
G
A
G
G
T
T
G
G
A
A
A
C
C
A
T
C
C
C
A
C
T
T
T
T
G
A
G
G
A
T
A
T
G
C
A
G
G
T
T
C
T
C
G
T
G
T
C
T
A
G
G
G
A
A
A
A
A
C
A
G
A
G
A
C
G
0.152642
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0.037182
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0
0.027397
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0.039139
1
3,662
C
A
G
T
G
A
G
G
T
C
A
C
T
C
A
A
G
G
A
G
A
C
A
A
T
C
G
A
A
G
A
C
T
G
T
T
G
G
G
A
C
C
A
G
G
A
T
G
C
A
G
A
G
G
C
T
C
G
G
C
T
T
A
C
T
C
0.078278
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0.02544
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3,663
C
T
G
T
G
C
A
G
T
A
A
G
C
C
G
A
G
C
C
T
C
T
G
C
A
T
C
C
T
G
G
T
C
C
C
A
A
C
A
G
T
C
T
T
C
G
A
T
T
G
T
C
T
C
C
T
T
G
A
G
T
G
A
C
C
T
0.080235
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0.023483
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0.021526
0.02544
0.015656
0.019569
0.037182
0.056751
0.050881
1
3,664
A
C
T
G
T
G
C
A
G
T
A
A
G
C
C
G
A
G
C
C
T
C
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C
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C
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G
G
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C
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A
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T
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C
G
A
T
T
G
T
C
T
C
C
T
T
G
A
G
T
G
A
C
C
0.080235
0.031311
0.052838
0.052838
0.04501
0.029354
0.003914
0.035225
0.039139
0.029354
0.035225
0.029354
0.031311
0.043053
0.04501
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.023483
0.027397
0.035225
0.021526
0.02544
0.015656
0.019569
0.037182
0.054795
0.050881
1
3,665
C
A
G
C
A
C
A
C
T
G
T
G
C
A
G
T
A
A
G
C
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A
G
T
C
T
T
C
G
A
T
T
G
T
C
T
C
C
T
T
G
A
0.080235
0.033268
0.050881
0.048924
0.04501
0.029354
0.003914
0.035225
0.037182
0.029354
0.035225
0.031311
0.033268
0.04501
0.04501
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.023483
0.027397
0.031311
0.021526
0.02544
0.015656
0.019569
0.037182
0.056751
0.052838
1
3,666
A
A
T
C
G
A
A
G
A
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T
G
T
T
G
G
G
A
C
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A
C
A
G
T
G
T
G
C
T
G
A
G
G
A
A
A
G
G
A
T
0.088063
0.031311
0.050881
0.050881
0.04501
0.029354
0.003914
0.033268
0.039139
0.029354
0.033268
0.031311
0.033268
0.04501
0.043053
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.023483
0.02544
0.035225
0.021526
0.02544
0.015656
0.017613
0.037182
0.054795
0.050881
1
3,667
T
C
G
A
A
G
A
C
T
G
T
T
G
G
G
A
C
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A
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A
G
T
G
T
G
C
T
G
A
G
G
A
A
A
G
G
A
T
G
T
0.088063
0.031311
0.048924
0.050881
0.04501
0.029354
0.003914
0.033268
0.039139
0.029354
0.033268
0.031311
0.033268
0.04501
0.04501
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.023483
0.02544
0.035225
0.021526
0.02544
0.015656
0.017613
0.037182
0.052838
0.052838
1
3,668
C
C
A
T
C
C
T
T
T
C
C
T
C
A
G
C
A
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A
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C
T
G
G
T
C
C
C
A
A
C
A
G
T
C
T
T
C
G
T
0.088063
0.031311
0.048924
0.052838
0.04501
0.029354
0.003914
0.033268
0.039139
0.029354
0.031311
0.031311
0.033268
0.04501
0.04501
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.023483
0.02544
0.035225
0.021526
0.02544
0.015656
0.017613
0.037182
0.052838
0.052838
1
3,669
A
C
C
A
G
G
A
T
G
C
A
G
A
G
G
C
T
C
G
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G
A
T
G
G
C
T
G
A
A
C
T
T
A
T
G
A
T
G
C
0.086106
0.031311
0.046967
0.054795
0.04501
0.027397
0.003914
0.033268
0.041096
0.027397
0.033268
0.037182
0.031311
0.04501
0.041096
0.021526
0.035225
0.023483
0.013699
0.005871
0.005871
0
0.02544
0.02544
0.041096
0.021526
0.021526
0.015656
0.019569
0.035225
0.050881
0.052838
1
3,670
T
A
G
A
C
A
T
T
G
G
A
T
T
G
A
C
T
G
T
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A
A
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C
A
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A
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A
G
T
T
C
A
G
C
C
G
0.099804
0.031311
0.041096
0.060665
0.046967
0.027397
0.001957
0.033268
0.04501
0.021526
0.027397
0.039139
0.031311
0.04501
0.04501
0.021526
0.037182
0.02544
0.013699
0.003914
0.005871
0
0.02544
0.023483
0.039139
0.021526
0.027397
0.013699
0.015656
0.035225
0.04501
0.048924
1
3,671
G
A
A
A
G
A
A
A
C
A
A
A
T
C
T
G
T
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A
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G
C
T
A
T
G
C
A
G
A
A
T
G
A
A
C
G
G
T
A
A
0.099804
0.029354
0.043053
0.058708
0.04501
0.029354
0.001957
0.035225
0.043053
0.017613
0.029354
0.039139
0.031311
0.043053
0.04501
0.023483
0.037182
0.02544
0.013699
0.003914
0.005871
0
0.023483
0.021526
0.041096
0.021526
0.027397
0.013699
0.015656
0.037182
0.046967
0.050881
1
3,672
G
G
A
C
A
T
A
G
A
A
T
G
C
T
C
A
G
A
G
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A
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A
T
G
A
T
G
G
A
T
A
G
A
G
T
C
T
T
C
A
A
T
0.086106
0.035225
0.033268
0.050881
0.054795
0.023483
0.015656
0.031311
0.043053
0.019569
0.02544
0.041096
0.027397
0.041096
0.046967
0.037182
0.037182
0.035225
0.011742
0.001957
0.009785
0.003914
0.019569
0.029354
0.041096
0.029354
0.02544
0.013699
0.02544
0.023483
0.033268
0.046967
1
3,673
C
T
C
G
T
C
T
C
A
G
T
A
A
A
G
G
C
T
C
A
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T
C
A
G
C
C
G
G
G
T
G
T
C
C
T
C
A
C
C
A
T
0.023483
0.048924
0.029354
0.041096
0.060665
0.02544
0.005871
0.029354
0.041096
0.029354
0.027397
0.019569
0.031311
0.048924
0.054795
0.041096
0.056751
0.062622
0.019569
0.007828
0.009785
0
0.015656
0.02544
0.04501
0.021526
0.037182
0.043053
0.029354
0.009785
0.017613
0.041096
1
3,674
A
T
G
G
A
T
T
G
C
T
G
T
T
G
T
T
G
T
T
A
T
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A
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C
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G
T
G
G
C
C
G
T
T
C
C
C
T
C
C
T
G
T
C
C
G
0.02544
0.041096
0.027397
0.04501
0.058708
0.013699
0.005871
0.029354
0.046967
0.029354
0.029354
0.041096
0.037182
0.041096
0.04501
0.037182
0.056751
0.058708
0.02544
0.007828
0.005871
0
0.021526
0.029354
0.037182
0.017613
0.031311
0.04501
0.037182
0.011742
0.031311
0.029354
1
3,675
T
G
G
A
G
A
T
G
A
C
C
C
A
G
G
T
G
G
A
G
G
G
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C
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G
A
G
T
T
T
T
C
A
C
A
C
G
T
T
T
C
T
T
G
C
0.105675
0.043053
0.041096
0.050881
0.039139
0.02544
0.005871
0.033268
0.035225
0.023483
0.033268
0.02544
0.02544
0.043053
0.037182
0.031311
0.04501
0.031311
0.015656
0.003914
0.001957
0.007828
0.015656
0.023483
0.048924
0.017613
0.035225
0.015656
0.027397
0.011742
0.048924
0.050881
1
3,676
G
C
A
A
A
G
C
C
A
C
T
G
A
G
G
T
C
C
G
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G
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C
C
A
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G
T
G
A
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G
A
A
G
T
C
T
G
T
T
0.021526
0.015656
0.041096
0.017613
0.023483
0.029354
0.013699
0.035225
0.023483
0.043053
0.048924
0.011742
0.02544
0.050881
0.029354
0.046967
0.050881
0.056751
0.04501
0.019569
0.007828
0.005871
0.023483
0.035225
0.039139
0.017613
0.048924
0.058708
0.037182
0.021526
0.005871
0.048924
1
3,677
A
C
A
T
C
T
G
C
A
A
G
G
T
G
G
A
G
C
T
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G
C
A
T
A
G
G
C
A
A
C
G
G
A
A
C
C
C
A
G
A
0.041096
0.027397
0.035225
0.033268
0.043053
0.037182
0.005871
0.041096
0.027397
0.02544
0.041096
0.017613
0.021526
0.048924
0.039139
0.046967
0.048924
0.048924
0.027397
0.015656
0.003914
0.005871
0.021526
0.029354
0.031311
0.027397
0.046967
0.031311
0.035225
0.02544
0.02544
0.043053
1
3,678
T
A
C
C
T
C
A
G
A
G
A
G
T
G
C
T
C
T
T
A
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C
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T
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C
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G
C
C
A
G
G
A
G
G
T
G
T
C
A
C
T
G
C
T
A
T
0.074364
0.017613
0.037182
0.052838
0.041096
0.019569
0
0.033268
0.058708
0.039139
0.029354
0.04501
0.027397
0.046967
0.029354
0.023483
0.054795
0.02544
0.015656
0.001957
0
0.001957
0.027397
0.043053
0.039139
0.02544
0.035225
0.013699
0.023483
0.027397
0.037182
0.052838
1
3,679
C
C
A
C
A
A
T
A
T
T
A
C
T
T
C
C
A
A
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C
G
C
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T
C
T
T
T
C
T
G
A
G
A
A
A
C
A
C
A
T
A
C
C
0.107632
0.035225
0.039139
0.072407
0.029354
0.023483
0.005871
0.037182
0.041096
0.015656
0.023483
0.058708
0.02544
0.035225
0.033268
0.02544
0.037182
0.033268
0.019569
0.003914
0
0.001957
0.019569
0.021526
0.046967
0.007828
0.033268
0.011742
0.027397
0.027397
0.066536
0.033268
1
3,680
C
C
C
T
C
A
G
A
A
C
A
C
T
A
T
T
T
T
G
G
T
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G
G
T
A
A
A
A
T
A
A
A
A
A
G
G
A
G
A
T
T
C
0.088063
0.019569
0.048924
0.052838
0.02544
0.021526
0.003914
0.033268
0.041096
0.033268
0.029354
0.062622
0.029354
0.050881
0.031311
0.02544
0.033268
0.033268
0.017613
0
0.001957
0.009785
0.037182
0.017613
0.048924
0.017613
0.033268
0.017613
0.023483
0.021526
0.043053
0.046967
1
3,681
T
C
C
A
C
T
G
C
T
G
G
T
G
G
T
C
G
G
C
A
T
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G
G
A
G
G
C
C
C
G
A
G
T
A
G
T
T
G
G
G
C
T
0.015656
0.017613
0.029354
0.011742
0.019569
0.02544
0.007828
0.050881
0.021526
0.041096
0.04501
0.017613
0.023483
0.02544
0.029354
0.033268
0.056751
0.04501
0.052838
0.033268
0.019569
0.041096
0.021526
0.050881
0.013699
0.035225
0.043053
0.054795
0.04501
0.019569
0.015656
0.037182
1
3,682
T
G
C
A
G
C
C
C
T
A
C
T
T
G
A
G
C
C
G
C
T
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G
C
T
G
C
T
G
G
A
T
G
C
T
C
T
A
T
G
A
G
A
0.009785
0.013699
0.023483
0.005871
0.015656
0.029354
0.009785
0.041096
0.015656
0.050881
0.048924
0.007828
0.019569
0.02544
0.023483
0.035225
0.066536
0.052838
0.062622
0.041096
0.019569
0.050881
0.015656
0.050881
0.013699
0.031311
0.04501
0.07045
0.043053
0.015656
0.007828
0.037182
1
3,683
A
G
G
G
C
C
G
C
C
A
C
T
A
T
G
A
A
T
G
C
A
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G
C
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C
C
C
T
A
C
T
T
G
A
G
C
C
G
C
T
G
C
A
A
C
T
0.007828
0.011742
0.021526
0.003914
0.011742
0.031311
0.009785
0.031311
0.011742
0.058708
0.048924
0.005871
0.015656
0.02544
0.019569
0.031311
0.066536
0.052838
0.07045
0.052838
0.019569
0.07045
0.013699
0.048924
0.011742
0.027397
0.046967
0.082192
0.041096
0.013699
0.003914
0.031311
1
3,684
T
C
A
C
C
C
T
C
T
A
C
G
A
G
G
A
C
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C
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C
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C
C
A
A
C
T
0
0.007828
0.017613
0.001957
0.009785
0.029354
0.011742
0.029354
0.011742
0.062622
0.052838
0.013699
0.013699
0.021526
0.017613
0.031311
0.072407
0.050881
0.072407
0.052838
0.019569
0.072407
0.015656
0.050881
0.009785
0.027397
0.052838
0.086106
0.041096
0.013699
0
0.029354
1
3,685
G
G
A
C
T
G
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A
A
A
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T
A
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0.033268
0.017613
0.037182
0.037182
0.021526
0.031311
0.015656
0.031311
0.037182
0.04501
0.043053
0.013699
0.013699
0.02544
0.039139
0.031311
0.050881
0.052838
0.054795
0.019569
0.007828
0.011742
0.019569
0.048924
0.029354
0.029354
0.041096
0.039139
0.043053
0.021526
0.023483
0.033268
1
3,686
G
T
A
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C
A
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G
C
T
G
A
A
0.048924
0.017613
0.033268
0.048924
0.031311
0.029354
0.009785
0.027397
0.041096
0.039139
0.037182
0.011742
0.017613
0.033268
0.041096
0.027397
0.054795
0.056751
0.035225
0.017613
0.007828
0.011742
0.019569
0.039139
0.035225
0.029354
0.041096
0.037182
0.04501
0.023483
0.023483
0.027397
1
3,687
G
C
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T
G
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A
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A
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0.04501
0.031311
0.027397
0.029354
0.027397
0.023483
0.011742
0.027397
0.02544
0.04501
0.039139
0.029354
0.029354
0.037182
0.037182
0.023483
0.054795
0.041096
0.04501
0.02544
0.013699
0.023483
0.019569
0.035225
0.027397
0.017613
0.052838
0.043053
0.039139
0.017613
0.023483
0.031311
1
3,688
C
A
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A
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A
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T
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G
0.086106
0.031311
0.039139
0.050881
0.04501
0.027397
0.013699
0.021526
0.031311
0.021526
0.017613
0.060665
0.033268
0.066536
0.050881
0.037182
0.017613
0.04501
0.019569
0.005871
0.007828
0.003914
0.015656
0.019569
0.035225
0.015656
0.037182
0.023483
0.017613
0.023483
0.033268
0.04501
1
3,689
G
A
A
G
T
C
C
A
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C
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A
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T
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C
0.052838
0.013699
0.052838
0.050881
0.017613
0.015656
0.001957
0.031311
0.062622
0.037182
0.046967
0.023483
0.039139
0.033268
0.029354
0.015656
0.050881
0.031311
0.02544
0.005871
0.013699
0.001957
0.017613
0.056751
0.056751
0.015656
0.029354
0.02544
0.041096
0.021526
0.031311
0.050881
1
3,690
C
A
G
C
A
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T
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C
0.107632
0.029354
0.033268
0.074364
0.048924
0.013699
0.003914
0.023483
0.029354
0.019569
0.033268
0.062622
0.041096
0.04501
0.046967
0.029354
0.033268
0.019569
0.013699
0
0.001957
0.001957
0.013699
0.02544
0.048924
0.007828
0.017613
0.015656
0.023483
0.023483
0.043053
0.068493
1
3,691
T
G
G
A
T
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C
T
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A
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C
A
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G
0.066536
0.031311
0.054795
0.043053
0.041096
0.027397
0.003914
0.031311
0.062622
0.029354
0.017613
0.027397
0.031311
0.054795
0.033268
0.02544
0.04501
0.043053
0.021526
0.005871
0.001957
0.003914
0.017613
0.023483
0.052838
0.029354
0.021526
0.019569
0.019569
0.017613
0.043053
0.052838
1
3,692
T
A
C
A
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A
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A
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G
A
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G
0.07045
0.031311
0.043053
0.052838
0.052838
0.023483
0.001957
0.043053
0.04501
0.015656
0.027397
0.041096
0.02544
0.041096
0.052838
0.037182
0.039139
0.035225
0.011742
0.001957
0.003914
0
0.031311
0.017613
0.048924
0.029354
0.031311
0.023483
0.017613
0.023483
0.02544
0.054795
1
3,693
T
T
A
A
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T
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C
T
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A
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0.111546
0.033268
0.050881
0.043053
0.033268
0.027397
0.013699
0.029354
0.054795
0.02544
0.02544
0.048924
0.021526
0.043053
0.033268
0.019569
0.029354
0.039139
0.015656
0.003914
0.001957
0.003914
0.023483
0.031311
0.041096
0.021526
0.015656
0.017613
0.023483
0.029354
0.052838
0.035225
1
3,694
T
T
A
G
A
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A
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T
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C
C
A
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G
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A
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G
T
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A
C
G
0.105675
0.029354
0.046967
0.07045
0.033268
0.017613
0.013699
0.029354
0.048924
0.021526
0.019569
0.050881
0.031311
0.039139
0.037182
0.013699
0.027397
0.037182
0.017613
0.003914
0.001957
0.003914
0.029354
0.017613
0.035225
0.021526
0.017613
0.019569
0.023483
0.029354
0.074364
0.031311
1
3,695
T
G
T
A
A
C
A
T
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T
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T
A
T
0.105675
0.029354
0.04501
0.07045
0.033268
0.017613
0.013699
0.029354
0.048924
0.021526
0.019569
0.050881
0.031311
0.039139
0.037182
0.013699
0.029354
0.037182
0.017613
0.003914
0.001957
0.003914
0.029354
0.017613
0.035225
0.021526
0.017613
0.019569
0.023483
0.029354
0.074364
0.031311
1
3,696
A
C
A
C
T
A
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G
T
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A
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A
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G
G
A
A
T
C
C
C
T
C
T
C
T
0.066536
0.033268
0.031311
0.07045
0.037182
0.011742
0
0.039139
0.046967
0.019569
0.031311
0.058708
0.043053
0.04501
0.043053
0.019569
0.02544
0.029354
0.017613
0.001957
0.001957
0
0.043053
0.037182
0.023483
0.019569
0.027397
0.015656
0.035225
0.015656
0.07045
0.039139
1
3,697
C
A
A
A
A
T
A
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C
A
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A
G
A
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C
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G
A
A
T
A
C
C
T
C
T
0.037182
0.02544
0.037182
0.027397
0.046967
0.04501
0.001957
0.033268
0.04501
0.027397
0.048924
0.023483
0.015656
0.023483
0.037182
0.050881
0.058708
0.054795
0.031311
0.015656
0.003914
0.005871
0.013699
0.04501
0.039139
0.017613
0.035225
0.037182
0.037182
0.033268
0.013699
0.031311
1
3,698
G
T
T
C
T
C
C
T
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A
A
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A
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C
A
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C
A
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G
G
G
T
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T
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C
C
T
C
C
A
T
0.09002
0.041096
0.029354
0.076321
0.039139
0.019569
0.013699
0.031311
0.035225
0.011742
0.02544
0.060665
0.027397
0.050881
0.048924
0.011742
0.02544
0.033268
0.017613
0
0.003914
0.005871
0.019569
0.029354
0.043053
0.017613
0.019569
0.005871
0.033268
0.033268
0.054795
0.04501
1
3,699
C
A
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T
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G
T
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A
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C
A
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C
T
A
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T
0.107632
0.037182
0.064579
0.058708
0.039139
0.015656
0.005871
0.043053
0.046967
0.02544
0.019569
0.048924
0.02544
0.035225
0.035225
0.023483
0.037182
0.019569
0.007828
0
0.003914
0.001957
0.017613
0.015656
0.058708
0.009785
0.02544
0.009785
0.013699
0.033268
0.066536
0.046967
1
3,700
G
T
A
T
A
C
C
T
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G
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A
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C
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A
T
G
C
C
A
T
T
0.09589
0.015656
0.041096
0.052838
0.039139
0.021526
0.013699
0.031311
0.04501
0.027397
0.031311
0.043053
0.017613
0.039139
0.033268
0.033268
0.027397
0.02544
0.027397
0.013699
0.007828
0
0.023483
0.041096
0.043053
0.021526
0.027397
0.019569
0.029354
0.035225
0.035225
0.041096
1
3,701
G
A
A
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G
C
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A
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T
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T
0.056751
0.02544
0.046967
0.04501
0.029354
0.027397
0.011742
0.037182
0.039139
0.037182
0.039139
0.033268
0.017613
0.037182
0.031311
0.035225
0.046967
0.041096
0.021526
0.001957
0.005871
0.011742
0.017613
0.041096
0.050881
0.021526
0.023483
0.02544
0.029354
0.023483
0.031311
0.056751
1
3,702
T
G
T
T
C
T
T
G
G
A
T
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T
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C
A
T
0.048924
0.037182
0.029354
0.043053
0.029354
0.023483
0.005871
0.048924
0.035225
0.021526
0.029354
0.088063
0.029354
0.041096
0.039139
0.017613
0.039139
0.050881
0.021526
0.001957
0.005871
0.005871
0.02544
0.041096
0.027397
0.019569
0.015656
0.023483
0.035225
0.035225
0.043053
0.041096
1
3,703
A
G
T
T
A
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C
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G
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C
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G
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T
G
C
C
C
T
T
0.113503
0.046967
0.039139
0.054795
0.041096
0.021526
0
0.039139
0.033268
0.019569
0.029354
0.048924
0.023483
0.050881
0.041096
0.009785
0.02544
0.029354
0.02544
0.001957
0.005871
0
0.029354
0.027397
0.031311
0.013699
0.023483
0.015656
0.023483
0.031311
0.07045
0.033268
1
3,704
A
A
A
G
A
A
A
G
G
G
G
A
C
C
T
A
C
C
A
A
T
G
C
C
C
T
G
T
T
C
T
T
C
G
T
A
T
C
G
T
G
C
A
A
T
G
T
A
T
T
G
G
C
T
T
G
C
A
T
A
G
C
T
G
A
T
0.072407
0.02544
0.04501
0.048924
0.058708
0.02544
0.005871
0.021526
0.043053
0.041096
0.033268
0.043053
0.019569
0.041096
0.037182
0.035225
0.046967
0.027397
0.021526
0.005871
0.003914
0
0.027397
0.019569
0.052838
0.021526
0.037182
0.011742
0.029354
0.029354
0.031311
0.037182
1
3,705
G
A
G
C
C
T
G
C
T
G
T
C
C
C
C
A
A
C
A
G
C
A
T
T
C
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C
T
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C
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C
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T
G
C
A
C
G
A
T
A
C
G
A
A
G
A
A
C
A
G
G
T
0.082192
0.029354
0.04501
0.050881
0.060665
0.023483
0.005871
0.023483
0.043053
0.039139
0.031311
0.041096
0.019569
0.037182
0.041096
0.033268
0.046967
0.02544
0.019569
0.005871
0.003914
0
0.02544
0.019569
0.050881
0.021526
0.035225
0.011742
0.027397
0.029354
0.033268
0.037182
1
3,706
T
G
G
A
A
A
G
A
A
G
G
C
A
A
T
G
A
T
G
T
A
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C
T
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A
A
T
G
T
T
G
G
T
G
T
T
G
T
T
G
A
A
G
A
T
0.076321
0.04501
0.048924
0.050881
0.048924
0.019569
0.003914
0.037182
0.041096
0.031311
0.015656
0.033268
0.033268
0.050881
0.050881
0.023483
0.033268
0.037182
0.007828
0.007828
0.007828
0
0.015656
0.027397
0.056751
0.009785
0.019569
0.015656
0.02544
0.033268
0.039139
0.052838
1
3,707
T
C
T
T
T
C
T
T
C
C
T
C
C
T
G
T
C
A
T
A
A
A
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A
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A
C
C
A
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C
C
G
G
A
T
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G
T
C
T
C
A
A
G
A
C
C
G
C
A
C
A
G
A
C
C
A
C
A
A
G
A
T
0.062622
0.037182
0.046967
0.056751
0.052838
0.02544
0.003914
0.027397
0.043053
0.029354
0.039139
0.033268
0.019569
0.033268
0.04501
0.029354
0.046967
0.041096
0.013699
0.005871
0
0.001957
0.017613
0.027397
0.046967
0.02544
0.02544
0.021526
0.039139
0.017613
0.048924
0.035225
1
3,708
T
T
T
A
C
A
A
C
C
A
G
G
C
A
C
T
G
A
C
T
A
C
A
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A
T
C
T
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C
T
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T
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C
A
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C
T
T
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A
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T
G
A
C
A
A
T
G
C
T
C
G
G
A
G
C
T
C
C
C
G
0.07045
0.039139
0.037182
0.046967
0.048924
0.02544
0.005871
0.043053
0.052838
0.019569
0.023483
0.043053
0.031311
0.035225
0.039139
0.027397
0.037182
0.031311
0.013699
0.009785
0.011742
0.003914
0.029354
0.035225
0.046967
0.017613
0.019569
0.011742
0.027397
0.039139
0.037182
0.039139
1
3,709
T
T
T
A
C
A
A
C
C
A
G
G
C
A
C
T
G
A
C
T
A
C
A
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A
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T
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C
T
T
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A
A
T
G
A
C
A
A
T
G
C
T
C
G
G
A
G
C
T
C
C
C
C
0.07045
0.039139
0.037182
0.046967
0.048924
0.02544
0.005871
0.043053
0.052838
0.019569
0.023483
0.043053
0.031311
0.035225
0.039139
0.027397
0.037182
0.031311
0.013699
0.009785
0.011742
0.003914
0.029354
0.035225
0.046967
0.017613
0.019569
0.011742
0.027397
0.039139
0.037182
0.039139
1
3,710
T
G
G
A
A
G
C
C
A
G
T
G
A
T
C
G
T
C
T
C
A
G
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C
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G
G
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T
C
C
A
G
C
T
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A
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G
A
T
G
G
T
G
G
T
C
T
C
A
G
T
A
G
C
A
T
C
G
0.056751
0.041096
0.027397
0.048924
0.037182
0.027397
0.017613
0.033268
0.046967
0.031311
0.017613
0.04501
0.039139
0.046967
0.035225
0.031311
0.04501
0.052838
0.011742
0.003914
0.005871
0
0.031311
0.02544
0.037182
0.021526
0.021526
0.023483
0.023483
0.021526
0.04501
0.046967
1
3,711
C
A
G
A
T
G
C
T
A
C
T
G
A
G
A
C
C
A
C
C
A
T
C
A
C
C
A
T
T
A
G
C
T
G
G
A
G
A
A
C
C
A
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A
C
T
G
A
G
A
C
G
A
T
C
A
C
T
G
G
C
T
T
C
A
0.056751
0.041096
0.027397
0.048924
0.037182
0.029354
0.017613
0.033268
0.046967
0.031311
0.017613
0.04501
0.039139
0.04501
0.035225
0.031311
0.04501
0.052838
0.011742
0.003914
0.005871
0
0.031311
0.02544
0.037182
0.021526
0.019569
0.023483
0.023483
0.023483
0.04501
0.046967
1
3,712
C
G
G
T
A
T
C
C
T
G
T
T
A
T
C
T
G
G
G
C
C
C
G
A
G
G
T
G
G
A
G
T
C
C
A
T
C
T
C
A
C
C
A
G
G
A
C
A
G
T
A
G
A
A
T
C
A
G
T
T
T
C
A
T
T
A
0.060665
0.033268
0.041096
0.029354
0.031311
0.02544
0.009785
0.054795
0.048924
0.017613
0.035225
0.023483
0.029354
0.027397
0.035225
0.029354
0.050881
0.046967
0.027397
0.009785
0.007828
0
0.019569
0.04501
0.035225
0.02544
0.023483
0.033268
0.033268
0.033268
0.033268
0.043053
1
3,713
T
C
C
C
A
T
G
G
C
T
C
A
C
T
G
C
A
A
A
G
A
C
T
T
T
G
A
A
G
T
A
A
T
A
G
G
T
G
A
C
C
C
C
A
G
G
G
G
A
C
A
G
C
C
C
G
G
T
G
A
C
T
T
C
T
C
0.029354
0.021526
0.037182
0.019569
0.043053
0.033268
0.009785
0.041096
0.052838
0.031311
0.041096
0.015656
0.017613
0.031311
0.033268
0.052838
0.062622
0.035225
0.039139
0.019569
0.001957
0.003914
0.011742
0.054795
0.031311
0.037182
0.048924
0.029354
0.033268
0.015656
0.011742
0.052838
1
3,714
A
C
A
T
A
A
A
G
A
T
G
T
A
A
A
A
C
A
T
A
C
T
T
C
T
A
G
A
A
G
T
G
C
A
A
G
T
G
A
T
G
C
G
T
C
C
G
C
T
G
C
C
T
T
C
T
C
C
C
A
G
G
C
A
A
A
0.080235
0.033268
0.056751
0.035225
0.043053
0.017613
0.005871
0.043053
0.050881
0.031311
0.02544
0.035225
0.029354
0.037182
0.033268
0.031311
0.043053
0.033268
0.013699
0.005871
0.001957
0.005871
0.02544
0.02544
0.056751
0.011742
0.029354
0.015656
0.031311
0.033268
0.039139
0.039139
1
3,715
T
G
A
T
G
C
G
T
C
C
G
C
T
G
C
C
T
T
C
T
C
C
C
A
G
G
C
A
A
G
T
A
C
A
A
T
C
T
A
C
C
A
T
C
A
T
C
C
A
G
C
C
T
T
G
G
T
A
G
G
G
C
T
T
C
T
0.082192
0.029354
0.062622
0.035225
0.048924
0.019569
0.005871
0.041096
0.050881
0.031311
0.02544
0.033268
0.029354
0.039139
0.029354
0.035225
0.041096
0.033268
0.015656
0.005871
0.001957
0.005871
0.02544
0.019569
0.054795
0.011742
0.031311
0.013699
0.031311
0.035225
0.043053
0.031311
1
3,716
A
C
T
T
G
T
T
A
T
G
G
A
G
G
A
A
G
C
C
G
A
G
G
T
T
T
T
A
A
C
T
G
C
G
A
G
A
G
T
A
A
A
C
C
T
G
A
A
G
G
T
A
A
G
T
G
A
C
A
A
C
A
A
G
C
G
0.119374
0.046967
0.052838
0.060665
0.039139
0.021526
0.011742
0.039139
0.029354
0.017613
0.027397
0.04501
0.013699
0.04501
0.04501
0.013699
0.015656
0.023483
0.011742
0.007828
0.005871
0.005871
0.02544
0.019569
0.04501
0.013699
0.027397
0.007828
0.029354
0.037182
0.068493
0.027397
1
3,717
A
C
A
G
C
T
A
A
A
A
A
C
C
C
C
T
T
T
T
A
A
A
G
T
T
G
T
C
A
T
C
A
T
T
G
T
A
A
G
A
A
A
C
T
T
G
G
C
A
A
A
G
T
C
T
T
T
A
A
G
T
A
C
T
T
A
0.074364
0.031311
0.050881
0.041096
0.041096
0.017613
0.009785
0.031311
0.050881
0.050881
0.027397
0.007828
0.029354
0.031311
0.046967
0.021526
0.052838
0.041096
0.031311
0.003914
0.003914
0.001957
0.02544
0.029354
0.043053
0.029354
0.021526
0.027397
0.027397
0.017613
0.031311
0.048924
1
3,718
T
C
A
C
C
T
T
T
A
G
G
A
C
C
G
G
C
A
T
A
G
C
T
G
C
T
C
G
A
C
A
G
C
G
G
G
C
A
G
T
C
C
T
A
C
T
G
T
T
T
T
T
G
A
G
G
A
A
G
T
G
A
G
A
T
T
0.02544
0.011742
0.048924
0.021526
0.021526
0.027397
0.001957
0.050881
0.041096
0.043053
0.050881
0.017613
0.021526
0.04501
0.033268
0.027397
0.054795
0.04501
0.033268
0.005871
0.005871
0.001957
0.043053
0.039139
0.031311
0.035225
0.050881
0.037182
0.037182
0.027397
0.017613
0.04501
1
3,719
G
C
A
G
C
T
G
G
G
A
A
A
G
G
A
C
G
T
C
G
G
A
C
T
T
G
A
G
G
C
G
C
C
G
C
A
G
C
A
T
G
A
C
T
G
C
T
T
C
C
T
C
C
A
G
C
A
G
G
A
G
C
T
T
C
T
0.043053
0.021526
0.046967
0.019569
0.029354
0.027397
0.005871
0.023483
0.037182
0.048924
0.060665
0.005871
0.017613
0.031311
0.039139
0.017613
0.07045
0.054795
0.050881
0.009785
0.003914
0.011742
0.009785
0.043053
0.039139
0.041096
0.037182
0.035225
0.064579
0.005871
0.009785
0.037182
1
3,720
A
G
C
T
C
C
T
G
C
T
G
G
A
G
G
A
A
G
C
A
G
T
C
A
T
G
C
T
G
C
G
G
C
G
C
C
T
C
A
A
G
T
C
C
G
A
C
G
T
C
C
T
T
T
C
C
C
A
G
C
T
G
C
C
T
T
0.043053
0.021526
0.046967
0.019569
0.029354
0.027397
0.005871
0.023483
0.037182
0.048924
0.060665
0.005871
0.017613
0.031311
0.039139
0.017613
0.07045
0.054795
0.050881
0.009785
0.003914
0.011742
0.009785
0.04501
0.039139
0.041096
0.037182
0.035225
0.062622
0.005871
0.009785
0.037182
1
3,721
C
C
G
A
C
A
G
T
T
G
G
A
A
C
T
G
C
T
G
G
C
A
C
A
G
G
T
C
C
T
C
C
C
G
C
T
C
A
G
C
T
G
A
T
G
A
G
G
T
G
G
A
G
C
C
A
T
C
G
A
T
G
C
G
G
T
0.027397
0.021526
0.033268
0.019569
0.035225
0.035225
0.007828
0.019569
0.035225
0.060665
0.043053
0.021526
0.019569
0.033268
0.02544
0.04501
0.074364
0.052838
0.046967
0.019569
0.011742
0.007828
0.003914
0.046967
0.035225
0.019569
0.054795
0.043053
0.037182
0.011742
0.013699
0.037182
1
3,722
C
A
C
T
C
C
C
A
G
A
G
G
C
C
A
A
T
G
C
T
G
A
A
G
C
C
A
T
C
G
A
C
T
T
C
C
T
C
A
G
C
T
C
C
C
T
C
C
G
T
G
A
G
C
T
C
A
G
A
C
A
G
T
G
T
A
0.009785
0.007828
0.043053
0.009785
0.023483
0.027397
0.003914
0.02544
0.076321
0.029354
0.072407
0
0.017613
0.019569
0.019569
0.02544
0.060665
0.046967
0.09002
0.021526
0.009785
0.003914
0.009785
0.09002
0.035225
0.039139
0.02544
0.046967
0.066536
0.007828
0.005871
0.029354
1
3,723
A
G
A
A
C
C
T
G
C
A
A
G
A
G
G
G
C
C
A
G
G
T
C
A
C
C
G
A
T
C
C
C
C
G
G
G
G
T
A
T
C
C
C
C
C
T
G
C
C
C
C
C
T
C
A
G
T
G
A
T
C
C
T
T
C
T
0.043053
0.033268
0.031311
0.017613
0.041096
0.04501
0.009785
0.021526
0.035225
0.033268
0.060665
0.019569
0.019569
0.017613
0.031311
0.041096
0.062622
0.04501
0.080235
0.009785
0.009785
0.005871
0.017613
0.039139
0.039139
0.02544
0.029354
0.027397
0.041096
0.017613
0.011742
0.037182
1
3,724
C
T
T
C
A
G
A
G
C
C
A
G
A
A
T
A
A
A
G
T
C
T
G
A
A
A
G
T
G
G
C
A
T
C
T
T
G
A
A
A
G
G
G
A
A
A
C
A
C
C
A
A
A
C
C
T
T
A
C
A
G
G
C
C
C
C
0.031311
0.015656
0.033268
0.027397
0.041096
0.048924
0.005871
0.027397
0.021526
0.033268
0.060665
0.009785
0.015656
0.02544
0.027397
0.046967
0.060665
0.07045
0.066536
0.011742
0.011742
0.005871
0.017613
0.031311
0.031311
0.027397
0.023483
0.046967
0.04501
0.033268
0.017613
0.027397
1
3,725
G
C
G
C
C
G
G
A
A
T
G
C
C
A
C
C
A
G
G
C
C
C
A
G
T
T
G
G
A
C
A
C
C
C
T
T
C
C
G
G
G
C
C
A
G
G
G
C
C
A
G
G
G
C
T
G
T
G
C
C
C
A
C
A
C
G
0.037182
0.017613
0.031311
0.027397
0.039139
0.041096
0.005871
0.031311
0.02544
0.039139
0.050881
0.007828
0.015656
0.023483
0.023483
0.048924
0.062622
0.07045
0.068493
0.013699
0.011742
0.007828
0.019569
0.033268
0.033268
0.023483
0.021526
0.052838
0.041096
0.027397
0.019569
0.027397
1
3,726
A
G
G
G
T
G
T
C
C
A
A
C
T
G
G
G
C
C
T
G
G
T
G
G
C
A
T
T
C
C
G
G
C
G
C
C
A
T
T
A
C
A
T
G
A
T
C
A
C
A
C
T
G
G
A
A
G
T
C
C
C
T
G
C
T
T
0.039139
0.019569
0.031311
0.027397
0.035225
0.041096
0.005871
0.029354
0.027397
0.041096
0.046967
0.005871
0.017613
0.027397
0.023483
0.04501
0.060665
0.074364
0.07045
0.013699
0.011742
0.007828
0.019569
0.033268
0.037182
0.023483
0.019569
0.052838
0.041096
0.023483
0.017613
0.029354
1
3,727
A
T
A
G
C
T
C
C
T
G
T
C
T
C
G
A
G
C
A
G
G
G
A
C
T
T
C
C
A
G
T
G
T
G
A
T
C
A
T
G
T
A
A
T
G
G
C
G
C
C
G
G
A
A
T
G
C
C
A
C
C
A
G
G
C
C
0.043053
0.021526
0.031311
0.027397
0.033268
0.039139
0.005871
0.035225
0.027397
0.039139
0.043053
0.005871
0.017613
0.027397
0.02544
0.046967
0.058708
0.07045
0.068493
0.013699
0.011742
0.007828
0.019569
0.037182
0.037182
0.021526
0.019569
0.046967
0.041096
0.023483
0.017613
0.035225
1
3,728
A
C
T
C
T
C
A
T
G
C
T
G
A
A
G
G
T
A
C
G
A
A
G
T
C
T
C
G
A
C
A
C
T
G
A
G
G
T
G
C
T
G
A
G
T
A
C
G
G
G
T
A
C
T
G
T
G
G
C
G
G
G
T
G
A
C
0.037182
0.019569
0.035225
0.027397
0.023483
0.035225
0.009785
0.039139
0.035225
0.037182
0.035225
0.011742
0.027397
0.031311
0.023483
0.039139
0.054795
0.060665
0.060665
0.019569
0.021526
0.007828
0.017613
0.037182
0.043053
0.02544
0.02544
0.043053
0.037182
0.023483
0.015656
0.039139
1
3,729
T
C
T
T
C
C
C
T
T
C
C
T
C
C
T
G
C
T
G
C
A
A
G
G
C
T
A
G
C
T
C
T
C
G
A
G
C
T
G
G
G
A
A
G
G
A
G
A
A
G
A
T
G
A
G
A
T
A
A
A
G
C
C
A
A
G
0.029354
0.019569
0.041096
0.033268
0.04501
0.033268
0.009785
0.011742
0.046967
0.050881
0.04501
0.009785
0.023483
0.031311
0.029354
0.037182
0.064579
0.054795
0.043053
0.015656
0.013699
0.007828
0.015656
0.033268
0.052838
0.033268
0.02544
0.041096
0.043053
0.009785
0.011742
0.037182
1
3,730
G
T
A
G
A
A
C
C
A
C
A
G
A
A
T
T
C
A
G
T
G
G
T
C
G
C
C
G
G
C
G
G
C
G
T
G
G
A
T
A
G
C
C
A
A
A
G
G
G
A
C
G
C
C
A
T
T
C
A
G
A
G
C
C
C
T
0.031311
0.017613
0.039139
0.04501
0.041096
0.029354
0.009785
0.013699
0.054795
0.054795
0.031311
0.019569
0.02544
0.031311
0.029354
0.033268
0.060665
0.056751
0.043053
0.013699
0.011742
0.007828
0.015656
0.039139
0.050881
0.031311
0.015656
0.035225
0.039139
0.011742
0.019569
0.041096
1
3,731
A
A
T
T
T
T
G
A
A
T
A
C
T
C
A
C
A
T
A
A
A
A
C
T
G
C
T
C
T
T
T
C
C
G
C
A
A
C
C
A
G
G
G
G
G
C
C
C
A
T
A
A
A
G
C
A
G
G
T
A
G
C
C
A
C
G
0.048924
0.027397
0.031311
0.031311
0.031311
0.027397
0.015656
0.015656
0.039139
0.029354
0.058708
0.027397
0.035225
0.041096
0.027397
0.023483
0.048924
0.046967
0.054795
0.011742
0.003914
0.003914
0.027397
0.035225
0.04501
0.019569
0.021526
0.039139
0.050881
0.019569
0.019569
0.041096
1
3,732
G
T
T
G
A
G
A
G
A
A
A
T
T
T
T
G
A
A
T
A
C
T
C
A
C
A
T
A
A
A
A
C
T
G
C
T
C
T
T
T
C
C
G
C
A
A
C
C
A
G
G
G
G
G
C
C
C
A
T
A
A
A
G
C
A
C
0.043053
0.027397
0.031311
0.029354
0.029354
0.027397
0.015656
0.015656
0.039139
0.031311
0.058708
0.029354
0.035225
0.043053
0.02544
0.023483
0.048924
0.048924
0.054795
0.011742
0.003914
0.003914
0.029354
0.037182
0.04501
0.017613
0.023483
0.039139
0.052838
0.019569
0.019569
0.039139
1
3,733
A
A
G
C
A
G
C
A
T
C
C
A
C
A
T
C
C
T
C
C
A
G
G
A
G
T
A
C
C
A
G
G
C
T
C
T
G
C
T
G
C
G
G
G
G
C
C
A
C
G
C
T
C
A
G
C
A
G
G
T
G
G
T
T
G
T
0.019569
0.021526
0.031311
0.007828
0.035225
0.02544
0.007828
0.035225
0.037182
0.052838
0.054795
0.013699
0.021526
0.046967
0.011742
0.043053
0.07045
0.058708
0.04501
0.007828
0.005871
0.005871
0.019569
0.058708
0.033268
0.021526
0.043053
0.043053
0.052838
0.017613
0.015656
0.035225
1
3,734
C
T
T
A
T
C
T
T
T
G
C
C
T
T
C
C
T
C
C
A
G
A
C
C
C
A
G
T
A
A
A
G
T
A
C
C
A
A
G
G
C
C
T
A
G
G
T
C
G
C
C
T
C
A
C
C
T
T
C
A
G
T
G
G
A
A
0.017613
0.019569
0.048924
0.007828
0.031311
0.037182
0.005871
0.037182
0.037182
0.033268
0.068493
0.009785
0.017613
0.037182
0.023483
0.046967
0.050881
0.062622
0.048924
0.003914
0.013699
0.003914
0.027397
0.048924
0.035225
0.029354
0.035225
0.04501
0.052838
0.015656
0.017613
0.029354
1
3,735
C
C
T
T
C
A
G
G
C
C
C
C
A
G
C
T
C
A
C
G
T
G
G
T
G
A
A
C
G
G
C
C
C
A
T
A
G
G
T
C
A
G
G
T
C
G
T
G
C
T
G
G
T
C
C
C
G
G
T
G
C
T
C
C
T
T
0.02544
0.023483
0.029354
0.02544
0.021526
0.041096
0.017613
0.029354
0.02544
0.033268
0.058708
0.017613
0.015656
0.031311
0.033268
0.043053
0.058708
0.064579
0.048924
0.017613
0.005871
0.005871
0.017613
0.041096
0.027397
0.023483
0.04501
0.056751
0.041096
0.019569
0.019569
0.035225
1
3,736
C
C
C
T
T
C
A
G
G
C
C
C
C
A
G
C
T
C
A
C
G
T
G
G
T
G
A
A
C
G
G
C
C
C
A
T
A
G
G
T
C
A
G
G
T
C
G
T
G
C
T
G
G
T
C
C
C
G
G
T
G
C
T
C
C
T
0.027397
0.023483
0.029354
0.02544
0.021526
0.041096
0.017613
0.029354
0.02544
0.033268
0.058708
0.017613
0.015656
0.031311
0.033268
0.043053
0.058708
0.064579
0.046967
0.017613
0.005871
0.005871
0.017613
0.041096
0.027397
0.023483
0.04501
0.056751
0.041096
0.019569
0.019569
0.035225
1
3,737
C
T
T
C
C
T
C
G
T
G
C
A
A
G
G
C
C
T
C
C
T
G
G
A
T
C
T
C
A
G
G
G
T
C
C
T
T
T
G
A
G
A
G
G
T
G
G
T
A
C
A
G
G
G
C
C
C
A
T
G
T
C
A
G
C
C
0.031311
0.011742
0.035225
0.021526
0.039139
0.027397
0.005871
0.02544
0.046967
0.02544
0.058708
0.009785
0.035225
0.046967
0.023483
0.054795
0.04501
0.048924
0.056751
0.009785
0.007828
0.007828
0.027397
0.050881
0.037182
0.017613
0.043053
0.041096
0.048924
0.013699
0.007828
0.037182
1
3,738
T
T
C
T
T
T
T
C
C
C
T
G
C
A
G
T
C
T
C
T
A
C
C
C
T
G
T
G
G
T
C
C
C
C
A
C
A
A
A
C
T
C
C
C
G
G
A
T
C
A
T
A
G
A
A
A
A
G
G
A
A
A
T
T
G
G
0.029354
0.015656
0.041096
0.019569
0.033268
0.021526
0.005871
0.027397
0.060665
0.041096
0.043053
0.009785
0.023483
0.029354
0.02544
0.039139
0.056751
0.048924
0.084149
0.017613
0.003914
0.003914
0.023483
0.050881
0.046967
0.021526
0.039139
0.041096
0.048924
0.011742
0.005871
0.029354
1
3,739
G
C
A
G
T
C
T
C
T
A
C
C
C
T
G
T
G
G
T
C
C
C
C
A
C
A
A
A
C
T
C
C
C
G
G
A
T
C
A
T
A
G
A
A
A
A
G
G
A
A
A
T
T
G
A
A
G
T
T
G
A
T
G
G
C
T
0.027397
0.015656
0.041096
0.019569
0.031311
0.021526
0.005871
0.027397
0.060665
0.041096
0.04501
0.009785
0.027397
0.02544
0.023483
0.037182
0.060665
0.050881
0.086106
0.017613
0.003914
0.003914
0.023483
0.050881
0.046967
0.021526
0.035225
0.039139
0.052838
0.011742
0.005871
0.029354
1
3,740
A
A
A
C
T
C
C
C
G
G
A
T
C
A
T
A
G
A
A
A
A
G
G
A
A
A
T
T
G
A
A
G
T
T
G
A
T
G
G
C
T
T
C
C
T
C
T
T
C
C
C
C
A
A
G
A
A
C
G
T
G
A
G
T
G
A
0.029354
0.013699
0.037182
0.021526
0.031311
0.023483
0.003914
0.027397
0.062622
0.037182
0.04501
0.009785
0.027397
0.027397
0.023483
0.039139
0.060665
0.054795
0.09002
0.015656
0.003914
0.003914
0.023483
0.050881
0.046967
0.021526
0.035225
0.041096
0.050881
0.011742
0.001957
0.027397
1
3,741
C
C
C
C
C
A
G
G
A
T
C
C
A
G
C
A
C
C
C
A
T
T
T
G
G
C
T
C
T
G
T
G
C
C
C
T
T
T
G
G
C
T
A
T
G
G
G
G
T
C
C
G
G
G
C
C
T
G
C
C
T
G
G
G
C
T
0.015656
0.013699
0.031311
0.011742
0.031311
0.031311
0.003914
0.023483
0.039139
0.052838
0.056751
0.009785
0.021526
0.023483
0.027397
0.050881
0.060665
0.066536
0.086106
0.017613
0.005871
0.007828
0.023483
0.056751
0.027397
0.011742
0.046967
0.054795
0.054795
0.013699
0.003914
0.017613
1
3,742
C
C
A
G
C
T
C
T
G
C
A
A
T
C
C
T
G
C
G
G
C
C
C
A
G
G
C
A
G
G
C
C
C
G
G
A
C
C
C
C
A
T
A
G
C
C
A
A
A
G
G
G
C
A
C
A
G
A
G
C
C
A
A
A
T
T
0.015656
0.013699
0.027397
0.011742
0.031311
0.031311
0.005871
0.023483
0.039139
0.050881
0.054795
0.009785
0.019569
0.021526
0.02544
0.050881
0.060665
0.064579
0.09589
0.023483
0.005871
0.007828
0.023483
0.058708
0.023483
0.013699
0.046967
0.054795
0.056751
0.013699
0.003914
0.013699
1
3,743
C
C
T
T
T
G
G
C
T
A
T
G
G
G
G
T
C
C
G
G
G
C
C
T
G
C
C
T
G
G
G
C
C
G
C
A
G
G
A
T
T
G
C
A
G
A
G
C
T
G
G
A
G
A
T
G
C
A
G
C
T
A
C
T
C
A
0.015656
0.011742
0.02544
0.011742
0.033268
0.031311
0.001957
0.02544
0.039139
0.050881
0.054795
0.009785
0.019569
0.021526
0.023483
0.052838
0.060665
0.064579
0.093933
0.02544
0.005871
0.007828
0.023483
0.060665
0.021526
0.013699
0.046967
0.058708
0.054795
0.013699
0.003914
0.015656
1
3,744
C
C
G
C
A
G
C
C
A
G
G
G
G
C
G
A
G
G
G
T
G
G
G
C
G
C
T
G
C
C
C
A
T
G
G
C
G
C
G
C
A
G
G
C
C
C
T
G
A
C
G
G
G
C
T
G
G
G
A
G
T
G
G
G
G
A
0.003914
0.007828
0.013699
0.001957
0.013699
0.037182
0.003914
0.013699
0.021526
0.056751
0.054795
0.001957
0.005871
0.023483
0.007828
0.031311
0.07045
0.050881
0.138943
0.060665
0.017613
0.054795
0.009785
0.054795
0.015656
0.02544
0.048924
0.086106
0.043053
0.003914
0
0.019569
1
3,745
A
G
T
C
C
T
T
A
G
A
A
A
A
G
C
G
C
T
C
C
C
C
G
A
A
G
C
C
C
A
T
G
T
C
G
G
G
G
C
T
G
C
A
G
C
C
G
C
C
C
C
A
C
T
C
C
C
A
G
G
A
G
T
C
C
C
0.015656
0.019569
0.031311
0.011742
0.035225
0.027397
0.02544
0.015656
0.029354
0.043053
0.062622
0
0.011742
0.027397
0.031311
0.04501
0.058708
0.050881
0.068493
0.02544
0.015656
0.027397
0.015656
0.04501
0.02544
0.027397
0.052838
0.07045
0.041096
0.011742
0.007828
0.023483
1
3,746
A
C
G
G
C
A
C
G
T
C
A
G
G
C
A
G
C
T
G
C
C
A
G
C
T
C
A
A
G
A
C
G
T
G
C
T
G
G
C
A
G
G
T
G
A
C
G
C
C
C
G
A
G
T
T
C
C
G
C
A
C
C
G
T
G
A
0.007828
0.015656
0.023483
0.001957
0.011742
0.027397
0.027397
0.023483
0.027397
0.052838
0.039139
0.003914
0.003914
0.009785
0.011742
0.043053
0.064579
0.041096
0.062622
0.076321
0.021526
0.082192
0.003914
0.048924
0.02544
0.023483
0.056751
0.097847
0.033268
0.007828
0.003914
0.019569
1