row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
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G
A
T
C
A
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A
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C
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C
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C
C
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A
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C
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A
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A
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G
A
G
G
A
G
G
G
C
C
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A
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C
A
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32,277
A
C
C
A
C
T
C
C
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A
A
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C
A
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A
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G
C
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32,278
A
G
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T
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A
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C
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A
C
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T
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C
T
C
A
C
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0
32,279
C
C
C
G
C
A
T
T
C
T
G
C
A
C
A
C
A
T
A
G
G
C
T
T
C
T
C
T
C
C
T
A
C
A
T
A
T
C
C
A
T
C
C
A
G
G
A
G
C
T
T
G
T
T
T
A
A
A
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C
C
C
T
C
T
T
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0
32,280
A
C
A
T
A
T
C
T
G
G
A
G
G
T
A
C
C
T
G
A
A
A
C
T
C
T
G
A
C
G
C
A
C
T
G
C
T
C
C
G
C
A
G
C
T
G
G
C
T
C
A
C
A
T
T
T
G
G
T
A
A
G
G
A
T
T
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0
32,281
T
A
A
C
A
G
A
C
A
T
A
A
T
C
T
G
A
A
A
T
A
C
T
A
T
G
T
A
T
T
A
C
C
G
A
A
A
A
A
G
C
C
T
A
A
A
A
A
G
G
T
G
G
C
A
T
T
T
G
A
T
T
G
C
C
T
0.086106
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0.072407
0.033268
0
32,282
T
C
T
G
G
T
T
T
T
A
C
T
T
G
C
A
A
A
G
T
A
G
T
G
G
G
A
A
G
A
T
A
C
G
G
G
T
A
T
T
T
C
C
T
C
G
T
C
G
A
G
C
T
C
C
T
C
A
G
C
G
G
C
A
C
T
0.084149
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0.033268
0.021526
0
32,283
C
T
G
G
G
G
C
A
G
T
G
G
C
T
G
G
A
G
A
T
C
T
G
G
C
A
G
G
C
C
A
A
T
G
C
T
T
G
G
G
A
G
C
C
A
T
T
G
T
G
C
C
C
C
C
C
T
C
C
C
T
G
C
C
T
G
0.003914
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0.009785
0
0.039139
0
32,284
A
G
T
T
T
G
G
C
T
G
G
T
G
A
T
C
T
C
A
G
C
C
C
A
G
G
A
C
T
A
T
A
C
A
G
C
A
C
A
G
A
T
G
G
G
G
G
A
G
G
C
A
G
G
G
A
G
G
G
G
G
G
C
A
C
T
0.013699
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0.02544
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0.099804
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0.007828
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0.064579
0.066536
0.033268
0.007828
0.001957
0.039139
0
32,285
A
G
A
G
G
G
C
C
C
G
C
C
C
G
C
C
A
T
G
C
T
G
C
C
C
T
A
C
T
A
C
A
C
G
G
T
C
A
A
T
G
G
C
T
C
C
T
G
G
G
T
G
G
T
G
C
C
A
C
C
G
G
A
G
C
T
0.02544
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0.052838
0.054795
0.037182
0.019569
0.005871
0.035225
0
32,286
G
G
C
G
T
C
A
G
C
C
C
C
A
G
A
T
G
T
T
A
C
C
T
C
A
C
T
G
C
C
C
A
C
G
G
T
T
C
G
C
C
G
C
T
C
T
A
G
C
A
G
G
A
G
G
C
G
G
A
A
A
C
G
G
T
T
0.017613
0.021526
0.027397
0.005871
0.023483
0.031311
0.015656
0.021526
0.043053
0.050881
0.064579
0
0.013699
0.011742
0.027397
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0.07045
0.052838
0.080235
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0.011742
0.02544
0.019569
0.062622
0.02544
0.029354
0.033268
0.066536
0.04501
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0.001957
0.033268
0
32,287
T
G
A
G
G
A
G
C
A
T
G
A
G
A
T
G
A
T
C
C
G
C
C
G
G
G
C
A
G
C
C
A
C
G
G
A
G
T
G
C
A
T
G
T
G
T
A
A
C
T
T
G
G
C
C
A
T
G
A
G
C
A
A
G
G
T
0.009785
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0.019569
0.048924
0.052838
0.04501
0.021526
0.009785
0.043053
0
32,288
C
C
C
G
A
A
G
C
C
G
C
A
G
A
A
A
C
C
G
A
A
G
C
C
G
A
A
C
C
A
G
G
C
C
C
C
C
G
G
C
C
G
C
T
C
C
T
C
C
G
C
C
A
T
G
C
C
C
G
A
G
C
A
G
C
A
0.017613
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0.011742
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0.09002
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0.007828
0.009785
0.013699
0
32,289
C
A
G
A
A
G
G
A
G
G
A
A
G
T
C
G
A
G
A
C
A
C
G
G
G
G
G
A
G
T
G
G
T
A
G
A
C
T
G
T
C
C
C
T
C
C
A
A
A
G
A
T
A
G
G
C
C
G
A
A
T
G
C
T
A
C
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0.031311
0
32,290
G
A
G
A
G
C
A
T
G
G
C
C
T
G
C
T
C
G
C
T
T
T
C
C
A
T
G
G
C
G
G
G
C
T
C
T
G
A
G
T
G
C
G
G
G
G
G
C
A
G
G
G
A
C
T
G
T
G
G
A
A
A
C
C
C
G
0.027397
0.013699
0.039139
0.021526
0.017613
0.037182
0.005871
0.021526
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0.048924
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0.04501
0.041096
0.046967
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0.011742
0.027397
0
32,291
T
G
A
C
A
T
C
G
T
G
C
G
G
C
A
G
G
G
T
C
C
T
G
G
A
G
G
C
C
A
C
T
T
G
C
G
C
G
G
C
T
G
G
G
C
C
A
C
A
G
A
G
T
C
T
A
C
T
T
T
G
A
A
G
G
C
0.133072
0.029354
0.033268
0.029354
0.066536
0.019569
0.007828
0.033268
0.035225
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0.013699
0.023483
0.035225
0.027397
0.035225
0.031311
0.033268
0.015656
0.029354
0.031311
0
32,292
C
T
T
A
G
C
A
C
A
T
A
C
T
G
A
C
C
T
G
A
G
T
T
T
T
T
C
T
C
C
A
T
C
A
A
A
T
G
C
C
A
A
C
T
G
A
G
A
A
A
A
T
G
T
A
C
G
G
T
A
C
C
A
A
G
T
0.091977
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0.04501
0
32,293
G
C
C
A
G
G
C
A
G
G
G
C
G
G
C
T
G
C
G
G
G
G
C
T
G
C
C
C
C
T
G
G
C
C
C
C
C
C
G
G
C
C
C
C
T
C
C
T
G
G
G
C
G
C
C
C
T
C
G
T
C
C
C
G
C
T
0.003914
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0
0.031311
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0.050881
0.015656
0
0.015656
0
32,294
C
C
A
G
A
C
A
G
C
T
A
T
T
A
A
A
A
G
A
A
G
C
C
C
A
G
G
A
A
G
T
T
T
C
T
G
C
G
C
A
G
C
G
T
T
G
G
A
G
A
T
G
A
G
G
A
G
A
C
T
G
T
G
G
A
A
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0
32,295
C
T
A
C
A
A
T
A
A
A
A
A
C
G
G
A
A
T
T
G
T
T
T
T
C
A
A
A
G
T
C
C
C
G
T
T
T
T
C
C
A
A
A
C
C
C
A
A
A
G
G
A
C
T
T
T
T
T
C
A
G
A
G
A
T
T
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0
32,296
T
A
C
A
T
T
T
C
A
T
A
G
A
C
A
G
G
G
G
T
G
G
T
T
C
C
T
C
T
T
T
G
C
G
G
T
G
C
T
G
A
A
T
G
A
A
A
T
T
G
C
A
A
T
G
T
G
T
A
A
T
G
A
T
C
A
0.084149
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0
0.02544
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0
32,297
T
T
T
C
A
G
C
A
C
C
A
C
C
A
A
A
T
T
A
T
G
C
A
G
A
T
G
T
G
G
T
A
T
C
A
G
A
G
G
A
A
G
A
A
T
T
C
T
C
T
A
G
A
C
A
C
A
T
T
C
C
T
C
C
T
C
0.09589
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0
0.037182
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0.023483
0.027397
0.064579
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0
32,298
T
C
C
C
A
G
A
G
G
A
C
G
A
G
G
C
C
C
T
G
G
G
G
G
T
T
A
G
C
T
G
C
T
C
G
A
T
G
T
C
T
C
C
T
G
C
C
A
T
G
T
A
C
C
A
A
G
G
T
A
A
C
C
C
C
C
0.021526
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0.011742
0.023483
0
32,299
G
T
G
C
T
T
G
G
G
C
T
T
T
C
C
C
A
C
C
T
C
T
T
C
C
A
G
C
A
T
T
T
C
C
T
G
G
A
T
G
A
T
G
A
C
T
C
T
C
A
A
G
G
C
T
C
T
T
C
C
C
A
G
C
A
G
0.054795
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0.017613
0.041096
0.031311
0.04501
0.013699
0.017613
0.037182
0
32,300
T
T
A
C
C
T
G
T
C
T
C
T
G
C
A
T
C
A
T
G
G
A
A
A
G
G
G
C
T
G
C
G
C
G
G
C
A
C
T
C
A
T
C
C
A
T
G
T
C
C
C
T
C
C
A
C
T
A
T
C
G
C
G
C
G
T
0.041096
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0.043053
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0.041096
0.04501
0.011742
0.009785
0.043053
0
32,301
G
T
T
G
T
T
G
G
T
C
T
C
A
C
T
G
A
C
T
T
C
A
A
G
A
A
T
G
A
A
G
C
C
G
C
G
G
A
C
T
C
T
C
G
T
G
G
T
G
A
G
T
G
T
T
A
C
A
G
T
T
C
T
T
A
T
0.043053
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0.019569
0.033268
0.013699
0.02544
0.046967
0
32,302
G
G
G
C
T
C
T
G
C
G
C
G
C
T
C
T
G
A
G
C
T
C
C
G
G
G
C
A
C
C
T
T
C
T
C
T
G
C
C
T
G
G
C
C
G
C
G
T
G
C
T
C
G
C
C
G
G
G
G
A
C
C
G
G
G
G
0.043053
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0.021526
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0.060665
0.04501
0.007828
0.015656
0.027397
0
32,303
C
C
T
T
G
G
C
C
T
T
T
C
G
G
G
G
C
C
C
A
G
A
A
C
G
C
T
A
C
G
G
A
C
G
C
C
G
G
G
C
G
G
C
C
A
G
G
A
G
G
G
G
T
T
G
G
G
C
T
C
C
C
G
C
T
A
0.035225
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0.056751
0.048924
0.011742
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0
32,304
G
A
T
A
T
A
A
A
A
G
T
C
T
G
T
C
T
A
T
T
C
T
C
T
T
T
A
G
A
G
A
G
T
G
A
T
T
G
A
C
T
G
C
C
T
G
G
A
G
G
A
T
G
A
G
A
A
G
G
C
A
A
C
C
C
C
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0.037182
0.041096
0.035225
0.035225
0.035225
0.015656
0.021526
0.039139
0
32,305
T
A
G
C
T
T
T
T
A
C
T
T
A
C
C
T
G
A
C
G
G
C
A
T
G
T
T
T
T
C
A
A
C
G
T
G
C
T
C
A
G
C
C
C
A
G
A
T
C
A
C
T
A
T
C
T
C
T
G
G
A
T
T
A
C
T
0.054795
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0.041096
0.041096
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0.031311
0.015656
0.033268
0.04501
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0.033268
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0.021526
0.02544
0.037182
0.021526
0.023483
0.054795
0.039139
0
32,306
C
A
A
A
G
G
T
G
C
T
T
T
C
T
G
C
C
T
T
G
A
A
A
A
T
A
G
A
T
T
C
C
T
T
T
C
A
T
T
T
T
C
C
C
T
C
T
G
T
A
G
T
A
G
T
G
A
G
T
C
G
G
T
A
T
A
0.078278
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0.037182
0.058708
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0.021526
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0.029354
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0.033268
0.041096
0.02544
0.043053
0.035225
0.017613
0.015656
0.007828
0
0.021526
0.02544
0.048924
0.015656
0.029354
0.035225
0.027397
0.027397
0.033268
0.043053
0
32,307
G
C
G
T
T
G
G
G
C
C
A
C
C
C
G
G
G
A
G
C
T
G
T
A
C
A
T
C
C
C
T
T
C
A
G
G
C
G
A
G
A
G
C
G
A
G
G
T
T
G
C
T
G
G
T
G
G
G
G
C
C
T
C
T
C
T
0.011742
0.019569
0.02544
0.003914
0.027397
0.035225
0.009785
0.031311
0.023483
0.058708
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0.017613
0.048924
0.080235
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0.021526
0.029354
0.043053
0.066536
0.043053
0.005871
0.009785
0.039139
0
32,308
G
A
G
T
G
G
C
C
T
G
G
T
G
C
A
C
A
T
C
T
G
C
T
G
A
G
C
C
C
T
C
T
C
C
G
T
G
C
A
C
A
G
T
G
C
T
C
T
C
T
G
A
G
T
C
A
C
C
A
G
A
T
T
C
C
G
0.027397
0.033268
0.021526
0.017613
0.048924
0.035225
0.011742
0.033268
0.04501
0.027397
0.046967
0.009785
0.031311
0.039139
0.023483
0.052838
0.068493
0.048924
0.043053
0.013699
0.009785
0
0.021526
0.039139
0.037182
0.029354
0.046967
0.031311
0.043053
0.011742
0.011742
0.039139
0
32,309
C
A
C
C
C
G
A
T
G
T
C
A
T
T
T
C
T
G
C
C
C
C
T
G
A
T
G
T
G
T
C
C
T
C
T
G
C
A
C
T
A
T
C
C
T
C
C
T
G
G
G
G
A
G
A
T
T
C
A
G
A
A
A
C
G
C
0.029354
0.033268
0.019569
0.015656
0.041096
0.033268
0.019569
0.027397
0.04501
0.037182
0.04501
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0.033268
0.027397
0.056751
0.033268
0.037182
0.013699
0.015656
0.037182
0
32,310
A
A
A
G
T
G
G
C
C
T
T
C
T
G
C
A
C
C
A
G
C
A
T
C
C
C
T
C
A
G
G
A
C
A
C
C
C
T
G
C
T
G
G
G
G
A
A
G
G
C
C
C
G
G
C
C
C
G
G
C
A
C
A
A
C
T
0.043053
0.019569
0.035225
0.023483
0.041096
0.029354
0.003914
0.017613
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0.043053
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0.074364
0.013699
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0.029354
0.019569
0.050881
0.062622
0.031311
0.009785
0.011742
0.033268
0
32,311
C
T
A
T
C
A
T
G
A
G
G
C
T
A
T
G
G
A
A
G
T
G
T
C
G
C
T
G
A
G
A
G
C
A
G
G
A
A
A
C
T
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A
G
G
T
C
T
C
C
C
T
T
G
A
A
T
G
A
G
A
G
A
A
A
A
0.062622
0.027397
0.041096
0.02544
0.033268
0.027397
0.005871
0.033268
0.064579
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0.04501
0.031311
0.029354
0.021526
0.041096
0.013699
0.023483
0.041096
0
32,312
T
T
A
T
T
T
T
C
T
A
A
A
T
A
T
T
T
G
T
A
T
T
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C
A
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C
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G
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G
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T
G
G
T
G
G
T
A
C
C
T
G
C
T
C
C
A
G
T
A
C
A
G
C
0.048924
0.013699
0.04501
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0.039139
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0.029354
0.02544
0.043053
0.037182
0.050881
0.021526
0.019569
0.023483
0
32,313
T
G
C
T
T
T
A
A
A
A
G
T
C
T
C
A
A
G
G
A
T
G
C
C
T
C
T
T
C
T
T
T
T
A
G
C
A
G
T
A
C
A
T
G
G
G
C
C
T
G
A
A
G
T
A
T
T
C
C
A
A
T
T
T
T
C
0.119374
0.033268
0.058708
0.054795
0.033268
0.013699
0.015656
0.041096
0.048924
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0.027397
0.064579
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0
0.007828
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0.048924
0.017613
0.02544
0.015656
0.019569
0.041096
0.052838
0.035225
0
32,314
C
T
T
T
A
A
G
G
G
G
A
T
T
G
A
C
C
A
G
G
A
T
A
T
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G
A
G
C
G
T
G
C
A
G
T
G
C
A
G
T
C
A
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A
A
A
T
C
T
T
T
C
T
A
C
A
T
G
A
A
A
G
T
T
G
0.035225
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0.046967
0.035225
0.029354
0.009785
0.019569
0.04501
0
32,315
A
G
A
G
G
C
A
G
A
C
A
G
A
G
C
A
G
G
C
G
C
G
G
G
C
A
C
C
G
G
T
G
C
C
C
A
G
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C
C
G
G
C
C
A
A
C
T
G
A
T
G
G
G
C
T
T
C
T
T
T
A
A
G
G
T
0.046967
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0.048924
0.033268
0.033268
0.009785
0.027397
0.041096
0
32,316
C
G
A
C
T
C
G
C
G
A
C
C
C
G
C
G
A
C
C
C
G
C
G
A
C
C
C
G
C
A
G
C
T
G
C
C
A
C
C
G
C
G
C
C
T
G
C
G
G
A
T
T
G
G
C
T
A
C
G
A
A
C
A
T
C
C
0
0.007828
0.003914
0.003914
0.009785
0.04501
0.009785
0.011742
0.005871
0.054795
0.048924
0
0.005871
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0.005871
0.019569
0.052838
0.050881
0.133072
0.086106
0.043053
0.103718
0.017613
0.04501
0.009785
0.035225
0.013699
0.105675
0.033268
0.013699
0
0.013699
0
32,317
C
C
C
T
G
C
A
T
C
T
C
C
A
G
G
C
C
C
T
T
G
C
C
C
A
G
G
G
G
T
C
C
C
G
G
G
A
G
T
G
A
A
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G
A
A
G
T
G
A
T
G
T
T
T
G
C
C
C
C
A
A
G
T
T
0.02544
0.023483
0.037182
0.017613
0.027397
0.037182
0.009785
0.023483
0.027397
0.033268
0.054795
0.013699
0.013699
0.033268
0.02544
0.048924
0.066536
0.054795
0.09002
0.021526
0.003914
0.011742
0.003914
0.031311
0.041096
0.015656
0.064579
0.050881
0.043053
0.009785
0.011742
0.027397
0
32,318
C
A
G
C
A
C
G
A
G
G
T
G
G
A
G
A
T
A
G
A
G
C
C
A
C
T
A
G
G
G
C
C
C
T
G
G
A
G
C
C
T
G
C
C
A
T
C
C
T
C
T
G
A
T
C
A
C
C
G
G
A
G
C
G
G
T
0.033268
0.021526
0.035225
0.009785
0.029354
0.029354
0.009785
0.031311
0.039139
0.048924
0.052838
0.013699
0.017613
0.021526
0.027397
0.035225
0.064579
0.052838
0.046967
0.029354
0.007828
0.015656
0.027397
0.046967
0.031311
0.027397
0.039139
0.056751
0.048924
0.015656
0.005871
0.027397
0
32,319
C
C
C
A
T
T
C
C
G
C
T
A
C
A
G
A
C
A
A
G
C
A
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A
C
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C
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C
T
C
C
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G
T
G
A
T
C
A
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G
G
A
T
G
G
C
A
G
G
C
T
C
C
A
G
G
G
C
C
C
T
0.035225
0.017613
0.037182
0.009785
0.027397
0.027397
0.011742
0.029354
0.037182
0.050881
0.050881
0.015656
0.017613
0.023483
0.027397
0.035225
0.062622
0.056751
0.048924
0.029354
0.007828
0.017613
0.02544
0.04501
0.031311
0.02544
0.041096
0.058708
0.050881
0.015656
0.005871
0.023483
0
32,320
T
G
C
C
A
A
C
G
A
G
C
A
G
T
G
C
C
A
G
A
T
C
C
T
G
T
T
T
G
G
C
A
T
G
A
A
T
G
C
C
A
C
C
T
T
C
T
G
C
A
G
A
A
A
C
A
T
G
G
A
G
G
T
A
A
C
0.064579
0.021526
0.029354
0.007828
0.07045
0.019569
0.017613
0.027397
0.029354
0.041096
0.039139
0.027397
0.007828
0.054795
0.027397
0.064579
0.062622
0.037182
0.02544
0.013699
0.005871
0.005871
0.011742
0.035225
0.02544
0.021526
0.076321
0.041096
0.029354
0.027397
0.005871
0.02544
0
32,321
A
G
A
A
A
A
G
A
A
G
A
A
G
C
C
G
A
C
G
T
G
G
G
G
C
A
G
G
C
C
T
T
C
G
C
G
G
G
A
C
T
G
G
C
G
G
G
A
G
C
G
G
A
G
G
A
A
C
G
C
T
A
T
C
C
T
0.023483
0.019569
0.029354
0.005871
0.027397
0.041096
0.021526
0.021526
0.041096
0.035225
0.046967
0.003914
0.019569
0.037182
0.017613
0.046967
0.048924
0.052838
0.064579
0.041096
0.019569
0.019569
0.013699
0.052838
0.033268
0.035225
0.027397
0.058708
0.037182
0.009785
0.003914
0.043053
0
32,322
A
T
A
C
A
C
G
T
C
T
G
A
T
A
A
T
C
A
G
C
A
A
G
A
G
A
A
A
A
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C
A
T
A
T
G
G
A
A
T
T
G
T
C
A
C
G
T
A
T
A
A
A
T
G
A
G
A
A
G
G
T
T
T
T
C
0.07045
0.039139
0.050881
0.050881
0.04501
0.011742
0.019569
0.02544
0.064579
0.023483
0.029354
0.023483
0.043053
0.035225
0.043053
0.023483
0.031311
0.041096
0.015656
0
0.003914
0.003914
0.029354
0.033268
0.043053
0.017613
0.013699
0.023483
0.035225
0.021526
0.054795
0.033268
0
32,323
G
A
T
G
G
T
C
C
C
A
C
A
T
T
T
C
T
T
T
T
C
C
C
T
G
A
G
T
C
A
A
G
C
T
T
T
C
A
G
T
G
G
C
T
T
C
A
C
A
T
C
C
T
C
T
G
A
A
A
A
T
G
A
A
G
G
0.125245
0.02544
0.048924
0.076321
0.031311
0.015656
0
0.037182
0.046967
0.013699
0.017613
0.052838
0.037182
0.041096
0.039139
0.023483
0.035225
0.029354
0.015656
0
0
0
0.019569
0.011742
0.056751
0.017613
0.02544
0.007828
0.023483
0.015656
0.056751
0.052838
0
32,324
T
T
G
A
T
C
T
G
A
A
A
C
T
G
C
T
G
G
G
T
T
G
A
G
A
T
A
A
A
A
G
A
T
G
T
A
A
T
C
A
T
G
G
C
T
G
T
C
A
T
T
T
T
C
A
A
G
T
G
T
G
G
C
T
C
C
0.068493
0.046967
0.054795
0.039139
0.048924
0.02544
0
0.039139
0.058708
0.02544
0.023483
0.029354
0.033268
0.035225
0.046967
0.029354
0.043053
0.033268
0.011742
0.007828
0.005871
0.001957
0.017613
0.031311
0.052838
0.015656
0.027397
0.015656
0.023483
0.021526
0.041096
0.04501
0
32,325
A
G
T
G
G
G
T
T
T
G
A
T
G
A
A
G
A
G
C
C
C
C
T
T
G
T
C
T
T
C
C
A
T
G
G
C
T
G
A
G
C
C
C
C
C
G
C
A
T
T
C
C
A
G
C
T
T
G
G
C
C
C
C
T
T
C
0.052838
0.033268
0.056751
0.015656
0.056751
0.007828
0.005871
0.021526
0.046967
0.033268
0.048924
0.003914
0.039139
0.039139
0.058708
0.02544
0.046967
0.039139
0.052838
0.005871
0.013699
0.005871
0.013699
0.033268
0.041096
0.023483
0.035225
0.046967
0.039139
0.011742
0.005871
0.039139
0
32,326
T
T
A
A
G
A
C
G
G
C
A
A
T
G
A
C
T
C
G
G
C
C
C
C
G
C
T
G
G
G
C
G
C
C
A
G
A
A
T
C
C
T
T
C
T
C
C
A
G
G
C
C
A
A
T
G
A
C
G
A
T
A
A
C
A
T
0.033268
0.019569
0.043053
0.017613
0.029354
0.017613
0.009785
0.033268
0.037182
0.052838
0.04501
0.007828
0.011742
0.029354
0.02544
0.037182
0.062622
0.048924
0.052838
0.027397
0.009785
0.019569
0.017613
0.04501
0.031311
0.027397
0.052838
0.056751
0.04501
0.005871
0.023483
0.023483
0
32,327
T
A
C
C
T
G
T
C
T
G
T
G
G
G
T
G
G
G
G
A
C
C
C
C
C
A
G
G
A
T
T
A
T
G
C
C
A
G
T
C
T
C
C
T
C
T
G
T
G
A
A
G
G
T
A
T
G
C
T
G
G
G
C
A
G
C
0.019569
0.015656
0.019569
0.015656
0.09002
0.039139
0.005871
0.023483
0.027397
0.039139
0.050881
0.007828
0.017613
0.037182
0.017613
0.084149
0.068493
0.048924
0.056751
0.011742
0.011742
0.005871
0.019569
0.033268
0.02544
0.033268
0.037182
0.035225
0.037182
0.02544
0.007828
0.031311
0
32,328
G
C
C
T
G
T
C
C
G
G
G
A
C
A
T
G
G
T
C
T
A
C
A
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G
G
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G
C
A
G
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G
A
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G
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G
G
C
T
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G
C
G
C
C
A
G
C
T
G
C
A
G
C
T
C
C
C
C
A
C
0.027397
0.015656
0.023483
0.011742
0.086106
0.037182
0.003914
0.02544
0.02544
0.039139
0.048924
0.013699
0.017613
0.035225
0.017613
0.088063
0.064579
0.050881
0.068493
0.011742
0.005871
0.005871
0.015656
0.035225
0.023483
0.027397
0.035225
0.033268
0.041096
0.021526
0.011742
0.031311
0
32,329
A
A
A
T
T
C
A
T
A
A
A
G
A
G
G
A
C
C
T
C
C
A
G
C
T
G
G
G
A
A
T
C
C
C
T
C
C
C
T
C
C
T
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C
A
T
G
A
G
G
T
T
T
C
A
G
C
C
C
C
G
C
C
A
G
T
0.041096
0.019569
0.02544
0.041096
0.037182
0.027397
0.009785
0.017613
0.037182
0.046967
0.033268
0.021526
0.029354
0.048924
0.035225
0.017613
0.050881
0.046967
0.041096
0.023483
0.017613
0.023483
0.009785
0.048924
0.037182
0.021526
0.029354
0.031311
0.043053
0.033268
0.013699
0.039139
0
32,330
A
G
A
G
C
G
A
C
A
A
C
T
T
C
C
C
A
T
T
C
G
G
A
C
T
T
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G
G
C
A
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T
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T
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T
A
C
A
G
A
G
A
A
G
T
G
G
T
T
T
T
C
T
C
T
0.041096
0.04501
0.046967
0.033268
0.043053
0.035225
0.019569
0.037182
0.043053
0.039139
0.031311
0.017613
0.011742
0.035225
0.027397
0.02544
0.052838
0.041096
0.017613
0.015656
0.009785
0.009785
0.021526
0.029354
0.046967
0.035225
0.019569
0.017613
0.033268
0.029354
0.050881
0.037182
0
32,331
T
G
G
T
T
T
C
T
C
C
C
T
C
G
G
G
A
A
C
C
A
A
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C
T
C
A
A
C
T
T
C
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G
G
C
A
A
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T
A
A
G
G
C
G
A
G
G
C
A
G
G
C
G
T
G
G
G
G
T
0.031311
0.019569
0.048924
0.001957
0.015656
0.04501
0.011742
0.029354
0.050881
0.039139
0.058708
0
0.011742
0.013699
0.031311
0.043053
0.058708
0.062622
0.058708
0.017613
0.009785
0.027397
0.009785
0.060665
0.031311
0.029354
0.046967
0.043053
0.052838
0.009785
0.007828
0.021526
0
32,332
G
G
C
T
G
G
T
G
G
G
A
G
G
A
A
T
C
C
A
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A
G
A
G
A
C
A
T
C
T
G
G
T
T
T
C
C
C
A
T
C
T
G
G
A
G
G
A
C
G
G
G
G
T
A
C
A
A
G
A
T
A
G
G
T
C
0.009785
0.009785
0.035225
0.007828
0.027397
0.043053
0.009785
0.021526
0.046967
0.033268
0.07045
0.005871
0.021526
0.023483
0.013699
0.058708
0.068493
0.07045
0.064579
0.021526
0.007828
0
0.009785
0.058708
0.035225
0.023483
0.037182
0.062622
0.056751
0.011742
0.003914
0.029354
0
32,333
A
G
G
C
T
G
C
A
T
G
G
A
G
G
T
G
C
T
C
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T
A
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C
T
T
G
T
A
C
C
C
C
G
T
C
C
T
C
C
T
0.009785
0.009785
0.035225
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0.029354
0.043053
0.007828
0.023483
0.039139
0.029354
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0.005871
0.019569
0.023483
0.013699
0.052838
0.072407
0.072407
0.076321
0.019569
0.007828
0
0.007828
0.054795
0.033268
0.031311
0.035225
0.060665
0.064579
0.009785
0.003914
0.02544
0
32,334
G
G
A
G
A
G
C
G
C
G
G
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G
C
T
A
G
A
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G
C
G
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A
A
C
C
G
G
G
C
G
G
T
G
G
G
G
A
C
A
C
T
G
0.013699
0.013699
0.005871
0.011742
0.017613
0.029354
0.019569
0.013699
0.015656
0.048924
0.058708
0
0.005871
0.005871
0.007828
0.039139
0.066536
0.041096
0.064579
0.074364
0.027397
0.093933
0.005871
0.058708
0.013699
0.02544
0.048924
0.097847
0.048924
0.003914
0.009785
0.011742
0
32,335
G
C
A
C
G
G
C
C
C
C
T
C
C
G
C
C
T
G
G
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A
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G
T
C
C
C
T
C
A
G
G
C
G
C
T
C
G
A
C
C
T
A
0.005871
0.009785
0.003914
0
0.017613
0.02544
0.027397
0.007828
0.013699
0.04501
0.066536
0
0.005871
0.009785
0
0.035225
0.054795
0.033268
0.062622
0.088063
0.039139
0.11546
0.005871
0.068493
0.009785
0.029354
0.039139
0.113503
0.048924
0.003914
0.001957
0.011742
0
32,336
T
C
A
G
T
T
C
T
G
G
A
A
C
A
T
C
T
A
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A
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A
A
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A
G
A
G
A
A
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C
C
A
A
G
C
T
A
T
T
G
0.074364
0.041096
0.043053
0.07045
0.046967
0.021526
0.001957
0.02544
0.064579
0.011742
0.023483
0.062622
0.035225
0.054795
0.029354
0.021526
0.019569
0.033268
0.015656
0
0.001957
0
0.029354
0.033268
0.041096
0.017613
0.011742
0.007828
0.027397
0.015656
0.084149
0.033268
0
32,337
C
A
G
A
A
A
A
G
G
A
G
T
A
A
T
A
A
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C
A
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C
C
A
G
G
T
G
T
G
A
T
G
T
G
G
G
A
G
A
A
G
T
0.064579
0.023483
0.039139
0.046967
0.054795
0.019569
0.001957
0.039139
0.050881
0.017613
0.027397
0.029354
0.027397
0.060665
0.041096
0.033268
0.048924
0.046967
0.011742
0
0.001957
0.003914
0.019569
0.027397
0.046967
0.027397
0.031311
0.029354
0.02544
0.029354
0.021526
0.050881
0
32,338
C
C
T
C
C
T
G
G
C
A
G
A
G
G
C
T
G
G
G
A
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A
G
C
C
C
A
G
G
C
A
G
T
G
C
C
C
T
G
T
G
C
0.003914
0.009785
0.021526
0.001957
0.033268
0.031311
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0.033268
0.056751
0.074364
0
0.007828
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0.072407
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0.009785
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0.058708
0.017613
0.029354
0.035225
0.09589
0.052838
0.009785
0.001957
0.017613
0
32,339
A
C
C
A
C
G
C
A
G
C
A
C
T
T
A
C
T
C
G
T
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C
T
G
G
G
C
C
T
G
C
G
C
T
C
C
A
T
A
T
C
T
0.009785
0.017613
0.017613
0
0.015656
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0.02544
0.015656
0.054795
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0.011742
0.013699
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0.04501
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0.105675
0.033268
0.017613
0.017613
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0.041096
0.02544
0.02544
0.04501
0.062622
0.052838
0.009785
0.001957
0.019569
0
32,340
C
T
G
G
G
C
C
A
A
G
G
C
C
A
A
G
A
A
G
G
T
G
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C
T
G
A
G
G
G
G
C
C
T
G
G
C
C
C
T
G
T
G
T
0.007828
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0.02544
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0.015656
0.04501
0.019569
0.021526
0.017613
0.031311
0.07045
0
0.009785
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0.04501
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0.074364
0.080235
0.04501
0.013699
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0.015656
0.04501
0.033268
0.101761
0.043053
0.001957
0.001957
0.033268
0
32,341
C
C
T
C
A
A
C
C
A
C
C
T
G
C
T
G
C
T
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G
G
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C
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A
G
C
G
G
G
C
T
T
0.009785
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0.064579
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0.037182
0.015656
0.035225
0.052838
0.054795
0.046967
0.017613
0.001957
0.023483
0
32,342
C
A
A
A
A
T
T
C
T
T
G
C
C
C
A
C
G
A
G
G
G
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C
A
G
G
G
G
G
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A
T
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T
C
C
T
G
G
C
T
C
T
0.015656
0.017613
0.019569
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0.054795
0.129159
0.017613
0.005871
0.013699
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0.046967
0.017613
0.02544
0.048924
0.058708
0.04501
0.005871
0.003914
0.031311
0
32,343
T
G
G
A
C
A
A
C
G
G
G
G
G
C
G
T
G
C
T
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C
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C
A
G
C
A
G
C
C
C
C
G
T
T
C
C
C
G
G
T
G
T
0.011742
0.011742
0.035225
0.005871
0.02544
0.033268
0.017613
0.019569
0.021526
0.056751
0.060665
0.005871
0.013699
0.013699
0.023483
0.043053
0.066536
0.066536
0.101761
0.033268
0.009785
0.009785
0.013699
0.04501
0.02544
0.021526
0.041096
0.068493
0.060665
0.019569
0.003914
0.013699
0
32,344
T
G
G
A
G
G
A
G
C
T
G
T
G
T
G
G
T
C
A
C
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C
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C
C
G
C
C
G
G
C
T
C
T
G
A
C
A
G
T
G
C
C
G
0.007828
0.015656
0.019569
0
0.02544
0.029354
0.007828
0.015656
0.029354
0.054795
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0.013699
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0.084149
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0.054795
0.021526
0.017613
0.050881
0.084149
0.056751
0.003914
0
0.029354
0
32,345
G
C
T
G
C
T
G
C
A
G
C
T
G
C
T
G
G
A
T
C
A
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C
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A
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A
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G
G
G
G
T
A
C
A
G
G
G
T
C
C
T
G
A
A
G
G
C
0.007828
0.013699
0.017613
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0.035225
0.033268
0.003914
0.013699
0.027397
0.052838
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0.009785
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0.048924
0.021526
0.019569
0.050881
0.07045
0.060665
0.005871
0.001957
0.029354
0
32,346
C
T
G
G
T
T
T
T
G
G
C
T
G
C
T
C
T
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C
A
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G
G
C
C
T
G
C
A
A
G
C
T
G
C
C
G
A
G
A
C
0.011742
0.009785
0.021526
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0.029354
0.048924
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0
0.009785
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0.04501
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0.035225
0.060665
0.07045
0.046967
0.003914
0
0.02544
0
32,347
G
G
A
A
A
C
G
T
T
G
A
C
G
G
A
G
G
C
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C
A
C
C
C
C
G
A
C
C
T
G
G
A
A
G
G
A
G
G
C
0.003914
0.017613
0.017613
0.001957
0.011742
0.050881
0.02544
0.007828
0.029354
0.041096
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0
0.015656
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0.013699
0.04501
0.058708
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0.072407
0.017613
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0.007828
0.052838
0.023483
0.02544
0.052838
0.076321
0.048924
0.007828
0
0.021526
0
32,348
T
G
C
A
T
T
T
T
T
T
T
G
G
T
A
G
A
G
A
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G
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G
G
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C
T
C
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A
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C
C
T
G
A
C
C
T
C
T
0.048924
0.013699
0.017613
0.021526
0.027397
0.046967
0.007828
0.029354
0.021526
0.037182
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0.027397
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0.068493
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0.066536
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0.011742
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0.048924
0.019569
0.015656
0.037182
0.068493
0.041096
0.013699
0.011742
0.037182
0
32,349
C
C
T
A
A
A
G
A
C
C
A
T
T
T
C
T
T
C
A
T
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G
C
T
T
C
C
T
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C
T
G
T
G
A
A
A
G
A
T
G
C
0.031311
0.013699
0.04501
0.015656
0.029354
0.029354
0.013699
0.019569
0.054795
0.048924
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0.037182
0.033268
0.033268
0.054795
0.04501
0.011742
0.017613
0.027397
0
32,350
T
G
A
G
A
C
C
C
C
C
G
G
C
C
C
T
G
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G
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C
C
C
A
G
T
G
C
C
A
G
G
A
A
G
C
C
C
G
G
C
0.001957
0.005871
0.007828
0.001957
0.017613
0.031311
0.015656
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0.029354
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0
0.009785
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0.066536
0.009785
0.02544
0.035225
0.103718
0.041096
0.001957
0
0.02544
0
32,351
C
A
C
C
C
A
C
C
G
T
C
C
C
A
C
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A
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C
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C
T
T
G
A
C
0.001957
0.003914
0.029354
0
0.013699
0.035225
0.02544
0.007828
0.027397
0.072407
0.056751
0
0.005871
0.017613
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0.084149
0.07045
0.07045
0.050881
0.013699
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0.048924
0.021526
0.023483
0.066536
0.09589
0.04501
0.001957
0
0.015656
0
32,352
C
C
T
C
A
C
C
T
G
C
A
T
C
A
G
G
A
G
G
C
G
G
A
G
G
G
G
C
C
T
G
C
C
G
G
C
C
T
C
G
T
G
C
C
G
G
A
G
G
A
C
A
C
G
G
A
A
C
T
T
C
A
C
G
C
T
0.001957
0.005871
0.017613
0.003914
0.027397
0.033268
0.031311
0.009785
0.013699
0.048924
0.076321
0.001957
0.009785
0.013699
0.009785
0.056751
0.078278
0.062622
0.103718
0.035225
0.011742
0.027397
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0.046967
0.013699
0.023483
0.04501
0.093933
0.046967
0.015656
0.003914
0.023483
0
32,353
C
A
G
G
G
T
G
G
C
A
C
C
A
G
C
T
C
A
G
C
T
G
G
C
G
C
A
T
G
T
C
C
T
G
T
G
C
T
T
T
G
T
G
G
A
C
G
C
T
G
C
T
G
T
G
T
G
C
T
C
C
T
G
A
A
C
0.003914
0.009785
0.021526
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0.041096
0.048924
0.009785
0.017613
0.017613
0.064579
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0.074364
0.09002
0.086106
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0.027397
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0.009785
0.023483
0.062622
0.068493
0.043053
0.009785
0.001957
0.017613
0
32,354
G
G
T
G
T
C
C
A
G
A
G
C
A
C
T
G
C
C
C
C
A
T
G
C
C
C
A
C
C
C
T
G
T
G
T
A
C
C
C
A
G
G
T
C
C
A
G
A
G
G
G
T
C
C
G
T
C
C
A
C
C
A
C
A
G
C
0.005871
0.011742
0.013699
0.005871
0.031311
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0.009785
0.017613
0.013699
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0.019569
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0.037182
0.011742
0.029354
0.054795
0.060665
0.046967
0.003914
0.001957
0.02544
0
32,355
A
G
C
T
C
T
G
T
C
C
C
A
G
G
T
A
C
T
C
C
C
G
G
G
G
G
G
A
T
T
C
A
C
T
G
A
T
G
G
A
C
T
G
G
C
C
G
A
G
A
G
G
A
C
A
C
T
T
A
G
C
T
T
C
C
A
0.029354
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0.027397
0.023483
0.060665
0.058708
0.052838
0.007828
0.013699
0.02544
0
32,356
G
G
T
T
C
T
T
T
G
C
T
C
T
G
T
T
C
T
A
G
T
C
C
T
C
C
T
G
G
G
G
C
C
G
G
G
G
C
C
A
C
A
G
C
C
T
C
T
C
C
C
T
T
G
C
C
C
G
G
T
G
G
C
C
T
T
0.007828
0.017613
0.027397
0
0.027397
0.041096
0.013699
0.02544
0.031311
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0.003914
0.011742
0.011742
0.021526
0.048924
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0.037182
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0.041096
0.023483
0.031311
0.029354
0.080235
0.04501
0.009785
0
0.02544
0
32,357
G
C
T
G
T
G
T
G
C
T
T
T
G
G
C
C
C
T
G
C
A
G
C
T
C
T
G
G
G
C
C
A
C
C
T
G
C
T
G
G
T
G
T
C
C
A
C
C
T
C
G
T
C
C
A
A
C
A
G
A
G
T
C
G
T
A
0.003914
0.009785
0.007828
0.001957
0.041096
0.035225
0.015656
0.019569
0.017613
0.054795
0.060665
0
0.009785
0.019569
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0.066536
0.097847
0.076321
0.074364
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0.007828
0.031311
0.056751
0.101761
0.037182
0.003914
0.001957
0.017613
0
32,358
G
G
G
A
C
G
C
C
G
T
C
T
T
C
C
T
C
T
G
G
G
A
T
G
T
C
C
T
G
G
C
C
C
C
T
A
C
T
G
A
G
A
G
G
C
A
A
G
T
G
C
C
T
A
C
T
C
T
C
A
G
C
T
G
T
A
0.005871
0.005871
0.02544
0
0.035225
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0.013699
0.019569
0.035225
0.043053
0.080235
0
0.011742
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0.031311
0.050881
0.072407
0.046967
0.009785
0
0.029354
0
32,359
A
A
C
C
C
C
G
T
G
A
G
C
A
G
T
G
G
A
G
G
G
C
A
G
G
G
C
A
G
G
G
A
C
G
C
T
G
G
T
G
C
C
G
G
T
G
C
A
G
G
G
G
C
C
T
G
A
G
G
A
C
G
G
T
C
T
0.005871
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0.019569
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0.031311
0.033268
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0
0.003914
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0.013699
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0.054795
0.082192
0.048924
0.005871
0.001957
0.027397
0
32,360
C
G
T
A
G
C
C
A
G
C
C
G
C
T
A
G
C
C
G
C
T
G
C
T
G
C
T
C
A
G
G
G
C
G
G
C
C
A
C
A
G
C
A
C
G
G
G
G
G
G
C
T
C
C
A
T
G
C
C
A
G
G
C
A
G
T
0.001957
0.011742
0.013699
0
0.033268
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0.046967
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0
0.013699
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0.082192
0.046967
0.001957
0
0.031311
0
32,361
A
C
A
A
G
G
A
T
G
G
G
C
T
C
G
T
G
G
C
T
G
T
G
A
G
C
C
A
C
C
C
C
T
G
C
A
C
A
G
G
G
A
C
A
A
C
C
T
T
C
C
G
T
G
T
G
C
T
G
A
G
T
G
A
C
C
0.003914
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0.041096
0.060665
0.039139
0.005871
0.003914
0.031311
0
32,362
T
T
G
C
G
G
G
C
G
G
C
C
G
T
G
A
A
G
A
G
C
A
G
C
C
T
G
G
C
G
G
A
C
G
G
T
G
T
A
A
A
C
C
T
G
C
A
C
A
G
G
T
G
C
A
C
T
G
C
G
T
T
G
T
C
A
0.019569
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0.035225
0.064579
0.080235
0.033268
0.013699
0.007828
0.023483
0
32,363
T
T
G
C
A
G
G
T
C
C
C
T
C
C
C
C
G
C
G
C
G
G
A
G
G
A
G
A
T
C
A
C
C
A
T
C
C
C
C
G
C
G
G
A
C
G
T
C
A
C
C
C
C
G
G
A
G
A
A
G
G
T
G
C
C
G
0.001957
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0
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0.02544
0.07045
0.060665
0.011742
0.003914
0.017613
0
32,364
T
C
T
G
C
A
C
T
G
A
G
G
G
C
T
C
A
C
C
T
T
C
T
C
A
A
T
G
G
T
G
G
C
C
T
C
C
T
C
A
G
A
G
A
C
G
T
C
A
T
A
C
A
C
C
A
C
A
C
A
C
A
C
C
A
T
0.017613
0.017613
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0.031311
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0.02544
0.02544
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0.021526
0.031311
0.035225
0.07045
0.041096
0.003914
0.001957
0.043053
0
32,365
T
T
G
T
C
C
G
G
A
A
C
C
G
C
C
G
C
G
C
C
G
G
A
A
G
C
C
G
C
T
G
T
C
T
T
T
C
C
C
G
T
C
C
C
T
C
G
C
C
G
G
A
A
G
T
G
G
T
C
C
T
C
T
T
C
G
0.02544
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0.015656
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0.031311
0.021526
0.021526
0.035225
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0.019569
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0.027397
0.035225
0.027397
0.060665
0.056751
0.013699
0.021526
0.007828
0
32,366
G
C
T
G
G
G
G
C
T
T
C
C
C
A
G
C
G
G
G
G
C
T
G
G
C
A
A
C
C
C
C
G
C
A
C
C
T
A
C
C
A
C
G
C
T
A
G
G
G
G
C
C
A
G
G
A
A
C
A
C
A
G
A
C
A
G
0.005871
0.013699
0.019569
0
0.02544
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0.017613
0.021526
0.04501
0.091977
0.037182
0.007828
0.001957
0.015656
0
32,367
T
G
T
G
G
T
T
T
A
G
C
C
C
T
C
C
C
C
C
A
G
C
A
G
C
C
A
G
C
A
G
A
C
C
C
C
C
T
G
G
G
C
C
C
G
G
G
C
T
G
T
C
C
C
T
A
T
A
C
A
C
G
G
A
T
A
0.013699
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0.013699
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0.031311
0.029354
0.066536
0.066536
0.005871
0.003914
0.027397
0
32,368
C
G
C
T
G
A
G
A
C
C
T
G
G
A
G
G
A
C
G
C
G
A
G
G
G
G
T
G
G
G
A
G
C
A
G
G
G
C
G
C
C
T
G
G
T
G
A
C
C
G
G
G
C
C
A
G
C
C
C
T
T
G
C
C
T
T
0.009785
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0.037182
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0.011742
0.011742
0.023483
0.046967
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0.011742
0.027397
0.041096
0.068493
0.052838
0.005871
0.005871
0.021526
0
32,369
G
G
C
C
T
G
C
A
C
C
A
T
C
T
G
C
G
T
G
C
T
C
C
T
G
G
A
G
G
C
G
G
C
G
G
G
C
T
G
G
G
T
C
C
G
C
A
T
G
G
G
G
C
C
C
A
C
C
C
C
C
C
A
T
C
T
0.009785
0.007828
0.017613
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0.017613
0.033268
0.011742
0.013699
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0.013699
0.015656
0.068493
0.09002
0.041096
0.011742
0.001957
0.023483
0
32,370
T
C
C
A
C
T
T
T
C
T
G
G
G
C
A
A
A
C
T
C
C
A
G
G
T
T
G
C
T
A
A
G
C
G
T
G
T
G
C
T
C
G
T
G
G
C
C
G
C
A
G
A
A
C
A
C
C
T
T
C
T
G
G
A
G
T
0.007828
0.011742
0.031311
0.003914
0.019569
0.035225
0.02544
0.015656
0.035225
0.04501
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0
0.003914
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0.113503
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0.023483
0.019569
0.043053
0.080235
0.035225
0.005871
0.005871
0.021526
0
32,371
C
T
G
C
A
C
A
C
T
C
C
G
A
G
T
C
C
G
T
G
C
C
C
T
G
C
A
G
C
C
A
G
T
G
T
G
T
G
T
A
C
A
G
C
T
C
C
T
G
A
A
C
C
C
C
A
G
G
C
G
C
G
T
C
C
C
0.003914
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0.013699
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0.031311
0.033268
0.021526
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0.052838
0.07045
0.056751
0.017613
0
0.017613
0
32,372
A
C
A
C
C
T
G
G
G
C
A
G
G
C
A
G
A
G
G
C
C
A
G
C
A
G
G
G
G
C
A
G
C
G
C
C
T
G
T
C
T
G
C
A
G
T
C
G
G
C
C
T
G
T
C
C
T
C
G
G
A
A
T
C
G
T
0.019569
0.017613
0.029354
0.007828
0.031311
0.046967
0.031311
0.017613
0.021526
0.02544
0.058708
0.003914
0.003914
0.023483
0.027397
0.076321
0.048924
0.056751
0.062622
0.033268
0.019569
0.041096
0.005871
0.039139
0.023483
0.033268
0.064579
0.066536
0.035225
0
0.003914
0.023483
0
32,373
T
T
A
A
C
C
A
A
G
T
A
A
G
G
C
A
C
A
G
G
A
G
G
C
T
G
C
T
C
C
A
C
C
A
T
C
T
C
T
C
C
T
G
C
C
C
G
G
C
T
G
A
T
C
C
G
A
A
A
C
A
C
T
T
T
T
0.027397
0.011742
0.031311
0.017613
0.019569
0.029354
0.007828
0.02544
0.043053
0.046967
0.062622
0.001957
0.027397
0.019569
0.021526
0.041096
0.080235
0.054795
0.058708
0.019569
0.009785
0.013699
0.013699
0.052838
0.033268
0.02544
0.046967
0.060665
0.046967
0.003914
0.005871
0.039139
0
32,374
C
T
C
C
C
C
T
C
G
C
C
A
A
C
T
C
C
T
T
G
G
C
T
T
C
C
C
G
T
G
T
G
C
G
G
A
G
G
T
G
T
C
C
G
G
C
C
T
G
A
G
C
A
C
G
G
A
G
C
G
T
G
T
C
C
T
0.001957
0.011742
0.02544
0.007828
0.02544
0.041096
0.011742
0.023483
0.035225
0.048924
0.062622
0
0.011742
0.007828
0.027397
0.054795
0.082192
0.064579
0.09589
0.027397
0.007828
0.011742
0
0.062622
0.017613
0.035225
0.048924
0.062622
0.052838
0
0
0.033268
0
32,375
C
C
A
C
A
T
T
G
G
C
C
T
T
C
G
T
G
A
T
G
C
G
G
G
A
G
A
A
G
A
A
A
C
G
G
G
T
G
C
A
G
G
C
C
T
G
G
G
G
C
C
C
C
G
A
G
A
A
C
G
C
A
T
C
T
T
0.011742
0.009785
0.017613
0.005871
0.019569
0.027397
0.009785
0.007828
0.031311
0.056751
0.066536
0.001957
0.015656
0.011742
0.017613
0.031311
0.082192
0.048924
0.113503
0.04501
0.019569
0.039139
0.005871
0.056751
0.015656
0.019569
0.052838
0.101761
0.031311
0.003914
0
0.021526
0