Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
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f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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G
C
T
C
C
T
G
G
G
A
G
C
T
G
G
C
G
C
A
G
G
T
0.011742
0.017613
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0.013699
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0.046967
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0.04501
0.015656
0.015656
0.029354
0
32,593
G
A
C
A
G
G
G
G
C
T
G
C
C
C
A
G
G
A
T
G
G
C
C
A
T
A
C
C
T
G
A
T
C
G
G
A
A
G
G
T
G
A
C
A
T
C
A
G
A
A
T
A
G
G
A
C
G
A
G
T
G
T
T
T
C
T
0.02544
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0.07045
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0.041096
0.039139
0.035225
0.066536
0.005871
0.003914
0.037182
0
32,594
C
A
C
C
T
G
T
G
C
C
C
G
C
T
G
G
A
T
C
T
T
G
G
G
G
C
A
T
C
T
C
G
T
G
C
A
G
C
A
G
A
C
T
G
A
G
T
G
A
G
G
A
G
A
G
G
G
T
C
C
T
C
A
T
C
A
0.013699
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0.07045
0.062622
0.001957
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0.037182
0
32,595
C
C
T
G
C
A
C
A
G
A
G
C
T
G
G
A
C
T
C
C
G
C
G
G
G
G
C
C
A
C
T
T
C
C
T
G
C
A
A
A
G
G
C
A
A
G
C
G
C
T
G
T
G
C
A
G
A
T
G
A
G
G
A
C
C
T
0.005871
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0.019569
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0.009785
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0.039139
0.046967
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0.039139
0.064579
0.066536
0.001957
0.003914
0.033268
0
32,596
C
A
T
C
T
T
G
T
T
G
C
A
G
G
A
A
G
G
A
C
A
A
C
A
C
A
T
T
T
G
G
A
T
A
G
G
G
C
G
G
T
C
C
A
A
A
A
A
G
G
T
G
A
T
G
G
G
G
T
G
C
T
G
C
A
C
0.043053
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0.019569
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0.043053
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0.017613
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0.027397
0.035225
0.046967
0.039139
0.039139
0.009785
0.007828
0.033268
0
32,597
C
A
T
A
T
T
G
C
T
T
C
T
G
G
G
A
A
A
A
A
A
T
G
T
C
A
A
T
A
T
G
T
T
G
G
A
A
A
C
T
G
T
T
C
C
T
T
T
G
C
T
C
A
T
A
G
T
C
C
T
G
A
G
G
A
G
0.097847
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0.046967
0.062622
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0.009785
0.005871
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0.041096
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0.052838
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0.017613
0.031311
0.021526
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0.001957
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0.037182
0.027397
0.048924
0.011742
0.031311
0.017613
0.027397
0.02544
0.056751
0.037182
0
32,598
C
C
G
T
G
T
A
C
T
G
G
C
T
T
A
T
C
G
A
G
T
T
G
T
T
C
C
A
A
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C
A
T
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T
T
C
C
C
G
A
T
A
A
A
C
G
T
C
A
T
T
T
C
C
T
T
C
A
T
T
A
A
A
A
C
0.123288
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0.076321
0.02544
0.011742
0.011742
0.031311
0.039139
0.033268
0.019569
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0.029354
0.04501
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0.023483
0.015656
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0.009785
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0.02544
0.017613
0.050881
0.011742
0.029354
0.009785
0.015656
0.023483
0.062622
0.046967
0
32,599
G
C
T
G
C
C
G
G
C
T
C
C
G
T
G
G
T
T
A
T
T
G
G
C
G
G
C
G
C
C
G
C
C
A
A
C
T
G
G
G
G
G
T
G
G
C
G
G
C
G
C
T
G
C
C
G
G
G
C
C
C
C
G
C
A
A
0.001957
0.015656
0.017613
0.001957
0.007828
0.019569
0.031311
0.013699
0.003914
0.043053
0.033268
0.001957
0
0.007828
0.015656
0.02544
0.04501
0.041096
0.097847
0.131115
0.017613
0.111546
0.001957
0.029354
0.015656
0.027397
0.035225
0.146771
0.039139
0.003914
0.003914
0.011742
0
32,600
G
C
C
G
C
C
A
A
C
T
G
G
G
G
G
T
G
G
C
G
G
C
G
C
T
G
C
C
G
G
G
C
C
C
C
G
C
A
G
G
A
A
G
G
A
C
G
G
C
A
C
G
A
A
C
T
C
G
G
C
G
G
C
G
T
A
0.001957
0.015656
0.017613
0.001957
0.005871
0.017613
0.031311
0.013699
0.003914
0.041096
0.033268
0.001957
0
0.007828
0.015656
0.023483
0.04501
0.039139
0.091977
0.136986
0.017613
0.119374
0.001957
0.027397
0.015656
0.02544
0.035225
0.156556
0.035225
0.003914
0.003914
0.011742
0
32,601
C
C
A
G
C
C
G
T
C
A
T
T
C
T
T
A
T
A
T
T
A
T
T
A
T
T
T
C
C
T
A
G
T
T
G
T
C
T
T
T
C
C
T
G
A
A
G
A
C
T
A
T
C
T
T
C
C
A
G
T
C
T
G
A
A
G
0.04501
0.02544
0.035225
0.023483
0.029354
0.031311
0.013699
0.027397
0.048924
0.031311
0.050881
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0.027397
0.027397
0.048924
0.04501
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0.029354
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0.011742
0.017613
0.054795
0.043053
0.023483
0.02544
0.04501
0.048924
0.02544
0.013699
0.035225
0
32,602
G
C
T
C
C
T
G
C
T
G
G
A
A
T
T
T
A
T
C
A
G
C
C
A
T
C
A
G
T
C
C
A
C
C
T
G
T
G
T
G
A
G
T
A
G
A
C
G
C
T
G
G
A
C
C
C
G
C
G
G
G
G
T
T
T
T
0.043053
0.013699
0.035225
0.015656
0.027397
0.027397
0.005871
0.02544
0.027397
0.031311
0.076321
0.005871
0.023483
0.017613
0.015656
0.031311
0.058708
0.048924
0.099804
0.021526
0.005871
0.021526
0.015656
0.050881
0.029354
0.023483
0.019569
0.050881
0.066536
0.017613
0.019569
0.027397
0
32,603
T
T
G
G
C
T
C
C
T
G
C
T
G
G
A
A
T
T
T
A
T
C
A
G
C
C
A
T
C
A
G
T
C
C
A
C
C
T
G
T
G
T
G
A
G
T
A
G
A
C
G
C
T
G
G
A
C
C
C
G
C
G
G
G
G
G
0.043053
0.013699
0.035225
0.015656
0.027397
0.029354
0.005871
0.02544
0.027397
0.031311
0.076321
0.005871
0.023483
0.017613
0.015656
0.031311
0.058708
0.046967
0.097847
0.021526
0.005871
0.021526
0.015656
0.050881
0.029354
0.023483
0.021526
0.050881
0.066536
0.017613
0.019569
0.027397
0
32,604
A
C
A
T
G
C
G
G
G
T
G
C
T
G
T
G
G
A
T
G
C
T
C
T
T
T
T
G
G
C
T
C
C
T
C
T
T
T
T
G
G
C
T
C
C
T
G
C
T
G
G
A
A
T
T
T
A
T
C
A
G
C
C
A
T
G
0.04501
0.009785
0.041096
0.015656
0.02544
0.027397
0.003914
0.021526
0.031311
0.029354
0.086106
0.003914
0.021526
0.017613
0.015656
0.031311
0.052838
0.046967
0.09589
0.021526
0.005871
0.019569
0.015656
0.058708
0.035225
0.023483
0.019569
0.048924
0.076321
0.011742
0.015656
0.02544
0
32,605
C
A
T
T
C
C
T
G
T
G
G
T
A
G
T
G
G
C
C
T
G
A
G
A
A
C
A
C
G
A
C
T
T
T
G
A
C
A
C
C
T
G
C
A
G
A
G
A
A
G
G
G
A
A
A
A
A
G
T
C
A
T
T
A
G
C
0.04501
0.021526
0.029354
0.056751
0.037182
0.033268
0.015656
0.02544
0.043053
0.015656
0.027397
0.082192
0.029354
0.046967
0.021526
0.031311
0.031311
0.033268
0.029354
0.019569
0.017613
0.005871
0.023483
0.027397
0.046967
0.029354
0.013699
0.019569
0.027397
0.029354
0.039139
0.04501
0
32,606
T
G
T
T
T
T
C
C
A
C
A
G
A
G
C
C
A
G
G
G
G
C
A
G
G
A
C
C
C
T
G
G
C
C
G
C
G
T
T
T
C
C
C
G
C
A
G
G
T
A
C
T
G
C
C
C
G
C
C
C
C
T
C
A
C
A
0.017613
0.021526
0.02544
0.001957
0.021526
0.029354
0.007828
0.023483
0.02544
0.039139
0.054795
0.001957
0.013699
0.009785
0.015656
0.031311
0.056751
0.04501
0.101761
0.062622
0.021526
0.068493
0.015656
0.04501
0.027397
0.02544
0.031311
0.084149
0.048924
0.003914
0.005871
0.015656
0
32,607
A
T
G
A
G
G
T
A
G
G
C
T
C
T
A
T
G
A
C
A
A
T
C
T
G
C
T
G
T
T
T
A
T
G
G
A
G
G
C
A
C
A
G
A
T
T
T
C
T
T
T
C
C
A
A
G
A
G
G
A
C
G
A
A
C
C
0.043053
0.031311
0.037182
0.035225
0.035225
0.023483
0.015656
0.035225
0.04501
0.023483
0.04501
0.02544
0.023483
0.033268
0.043053
0.033268
0.046967
0.033268
0.031311
0.011742
0.011742
0.007828
0.02544
0.039139
0.037182
0.027397
0.054795
0.031311
0.037182
0.017613
0.02544
0.033268
0
32,608
G
A
G
T
G
A
T
A
T
A
G
T
C
T
C
T
C
A
G
C
T
G
G
G
A
A
C
A
T
G
T
T
C
G
G
T
C
A
T
C
A
C
T
T
G
C
A
C
A
A
A
T
C
A
G
T
A
C
T
T
G
A
C
C
T
T
0.091977
0.031311
0.074364
0.043053
0.029354
0.029354
0.003914
0.033268
0.058708
0.019569
0.048924
0.02544
0.02544
0.017613
0.046967
0.015656
0.023483
0.019569
0.027397
0.009785
0.003914
0.001957
0.029354
0.033268
0.058708
0.023483
0.011742
0.013699
0.035225
0.02544
0.04501
0.043053
0
32,609
A
A
A
C
A
A
A
C
T
T
A
G
A
C
C
T
A
G
T
A
A
G
A
G
G
C
A
C
A
G
C
A
T
C
T
G
C
A
G
A
T
G
T
T
T
C
C
A
C
T
G
A
C
A
C
T
C
G
G
A
A
A
G
C
C
C
0.074364
0.031311
0.04501
0.041096
0.058708
0.015656
0
0.037182
0.054795
0.017613
0.037182
0.019569
0.02544
0.043053
0.04501
0.035225
0.041096
0.029354
0.027397
0.005871
0.003914
0.001957
0.023483
0.037182
0.043053
0.019569
0.037182
0.02544
0.029354
0.02544
0.029354
0.039139
0
32,610
A
G
C
T
C
C
T
A
A
C
A
C
A
G
G
C
C
G
A
G
C
G
A
A
T
C
A
G
C
A
G
A
T
G
G
G
A
G
G
G
G
G
A
T
T
C
T
T
T
T
C
C
G
G
T
G
T
G
C
T
C
A
C
A
G
G
0.064579
0.02544
0.02544
0.056751
0.037182
0.013699
0.003914
0.041096
0.039139
0.027397
0.031311
0.037182
0.046967
0.043053
0.02544
0.027397
0.052838
0.02544
0.037182
0.007828
0.005871
0.001957
0.033268
0.02544
0.046967
0.021526
0.021526
0.019569
0.031311
0.021526
0.037182
0.064579
0
32,611
C
T
G
T
A
C
A
A
A
G
G
C
C
A
C
A
T
C
C
A
T
C
A
T
G
G
G
C
C
T
G
T
T
G
G
T
C
A
C
A
G
T
A
A
G
A
G
G
A
A
A
T
G
T
C
T
G
G
G
G
T
T
T
C
A
C
0.054795
0.04501
0.052838
0.017613
0.041096
0.023483
0.019569
0.035225
0.041096
0.023483
0.043053
0.007828
0.033268
0.027397
0.043053
0.037182
0.046967
0.046967
0.033268
0.013699
0.009785
0.007828
0.017613
0.02544
0.052838
0.017613
0.027397
0.039139
0.041096
0.019569
0.017613
0.037182
0
32,612
A
T
G
G
A
A
C
C
A
A
A
C
A
C
C
A
C
G
T
C
A
A
C
T
G
G
A
A
C
T
C
T
C
C
T
T
G
C
A
A
A
C
G
A
A
G
G
C
T
G
A
A
G
A
T
C
A
A
G
A
A
T
G
A
C
T
0.046967
0.02544
0.029354
0.046967
0.041096
0.027397
0.013699
0.02544
0.035225
0.035225
0.035225
0.02544
0.027397
0.048924
0.039139
0.035225
0.048924
0.035225
0.04501
0.009785
0.003914
0.011742
0.017613
0.033268
0.039139
0.02544
0.043053
0.019569
0.033268
0.019569
0.023483
0.052838
0
32,613
T
G
A
T
G
T
T
T
T
T
A
A
A
A
A
A
A
C
A
C
C
C
A
T
C
T
C
C
A
G
C
T
C
A
C
A
C
A
C
T
G
T
T
T
T
C
T
G
G
A
A
A
T
A
A
A
G
C
C
C
T
A
C
T
C
A
0.101761
0.027397
0.060665
0.039139
0.043053
0.023483
0.005871
0.02544
0.056751
0.021526
0.033268
0.031311
0.039139
0.031311
0.041096
0.033268
0.037182
0.048924
0.023483
0
0.003914
0.001957
0.015656
0.023483
0.046967
0.017613
0.011742
0.029354
0.027397
0.019569
0.039139
0.039139
0
32,614
T
G
G
G
T
G
G
G
C
A
A
C
A
G
G
A
G
T
T
T
G
T
C
A
A
A
G
A
T
G
T
T
T
A
T
C
A
G
G
T
C
G
C
G
A
T
A
T
A
G
A
T
C
C
T
T
T
G
T
T
T
T
G
C
C
C
0.119374
0.041096
0.04501
0.037182
0.043053
0.017613
0.003914
0.029354
0.037182
0.027397
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0.043053
0.021526
0.037182
0.037182
0.029354
0.007828
0.005871
0.005871
0.013699
0.031311
0.033268
0.013699
0.031311
0.029354
0.033268
0.017613
0.046967
0.027397
0
32,615
T
A
A
A
C
A
A
T
C
C
T
T
C
C
G
T
G
G
A
A
T
C
T
G
T
C
C
C
A
C
C
A
C
A
A
G
T
T
T
G
A
G
T
T
G
C
T
G
T
T
T
C
T
T
C
A
G
C
A
T
C
T
T
C
A
A
0.086106
0.041096
0.046967
0.062622
0.037182
0.027397
0.005871
0.029354
0.023483
0.027397
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0.060665
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0.031311
0.02544
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0.001957
0.001957
0.027397
0.009785
0.046967
0.011742
0.033268
0.011742
0.029354
0.013699
0.058708
0.043053
0
32,616
T
C
G
G
C
G
T
C
T
T
C
C
T
G
C
A
C
C
G
G
G
T
C
C
G
G
G
C
C
T
C
C
C
C
A
G
C
C
T
C
C
A
G
C
A
G
C
T
A
C
T
G
C
A
C
T
G
C
A
G
C
A
G
C
C
T
0.027397
0.019569
0.015656
0.017613
0.021526
0.033268
0.037182
0.007828
0.015656
0.046967
0.029354
0.011742
0.009785
0.019569
0.023483
0.046967
0.052838
0.062622
0.060665
0.066536
0.021526
0.078278
0.001957
0.029354
0.013699
0.027397
0.046967
0.093933
0.031311
0.005871
0.011742
0.011742
0
32,617
A
A
G
G
T
T
G
G
G
G
A
A
G
C
G
C
C
T
G
G
A
A
T
T
T
G
G
G
A
A
G
C
C
G
C
C
T
T
C
A
C
A
C
A
T
G
T
C
T
T
C
A
T
C
G
C
C
G
C
T
G
C
C
G
T
T
0.058708
0.035225
0.046967
0.023483
0.043053
0.039139
0.009785
0.027397
0.048924
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0.013699
0.023483
0.039139
0.035225
0.048924
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0.017613
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0.015656
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0.035225
0.037182
0.041096
0.017613
0.033268
0.02544
0.007828
0.027397
0.043053
0
32,618
A
A
G
A
T
C
T
T
C
A
A
T
G
T
T
A
G
T
A
C
T
T
T
T
C
T
G
T
T
C
C
T
C
C
T
T
T
C
T
T
A
G
G
T
G
G
T
C
A
T
C
T
G
A
A
A
T
G
C
A
C
A
G
A
A
T
0.09589
0.039139
0.039139
0.064579
0.056751
0.027397
0.003914
0.031311
0.041096
0.017613
0.023483
0.043053
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0.041096
0.048924
0.029354
0.019569
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0.019569
0.001957
0.001957
0.003914
0.035225
0.019569
0.031311
0.017613
0.011742
0.013699
0.021526
0.033268
0.064579
0.035225
0
32,619
T
G
T
G
A
T
C
T
C
A
G
C
T
C
A
C
T
G
C
A
T
C
C
T
C
C
G
C
C
T
C
C
T
G
G
G
T
T
C
A
A
G
C
A
G
T
T
C
T
C
C
T
G
C
C
T
C
A
G
C
C
T
C
C
C
C
0.076321
0.017613
0.011742
0.02544
0.048924
0.023483
0.003914
0.029354
0.060665
0.031311
0.039139
0.068493
0.039139
0.023483
0.021526
0.046967
0.050881
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0.011742
0.003914
0.003914
0.048924
0.050881
0.017613
0.021526
0.029354
0.029354
0.033268
0.019569
0.015656
0.029354
0
32,620
G
G
A
G
C
T
C
A
G
G
T
C
G
G
T
A
T
C
T
T
A
G
C
C
C
A
A
A
G
T
C
C
C
G
G
A
A
C
T
C
G
A
T
C
T
G
C
C
C
G
C
C
C
T
G
A
G
G
C
C
A
G
G
G
G
T
0.037182
0.02544
0.037182
0.017613
0.033268
0.033268
0.007828
0.023483
0.039139
0.039139
0.064579
0.011742
0.017613
0.031311
0.02544
0.037182
0.054795
0.052838
0.062622
0.011742
0.005871
0.009785
0.019569
0.054795
0.035225
0.027397
0.027397
0.041096
0.052838
0.007828
0.019569
0.035225
0
32,621
G
G
G
C
T
T
G
A
G
G
G
A
C
A
G
A
C
A
G
A
G
G
C
A
G
A
G
A
C
T
G
T
C
G
G
A
C
C
C
C
T
G
C
T
A
G
T
G
G
G
A
C
C
T
T
T
G
A
A
G
A
C
C
C
T
T
0.023483
0.017613
0.04501
0.007828
0.050881
0.027397
0.007828
0.037182
0.048924
0.046967
0.050881
0.007828
0.011742
0.021526
0.041096
0.056751
0.066536
0.058708
0.04501
0.003914
0.005871
0.005871
0.017613
0.054795
0.021526
0.039139
0.052838
0.035225
0.050881
0.009785
0.007828
0.021526
0
32,622
G
C
A
G
C
T
G
C
C
G
G
G
A
A
G
G
A
T
T
G
C
A
T
C
A
C
C
A
T
A
C
A
C
A
G
T
G
C
C
A
C
C
T
T
C
G
C
C
T
G
G
T
C
C
C
A
G
G
A
A
A
G
C
C
C
A
0.019569
0.019569
0.017613
0.011742
0.035225
0.04501
0.005871
0.015656
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0.029354
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0.078278
0.056751
0.09002
0.021526
0.005871
0.005871
0.013699
0.048924
0.02544
0.019569
0.050881
0.058708
0.048924
0.023483
0.007828
0.017613
0
32,623
C
T
T
C
C
T
C
T
G
C
C
T
G
G
A
A
G
A
A
G
T
T
G
A
C
C
C
T
G
G
T
G
T
C
G
T
A
G
A
C
T
C
A
A
G
T
T
C
C
T
C
T
G
G
A
A
G
C
G
G
T
G
A
G
T
C
0.023483
0.019569
0.041096
0.005871
0.029354
0.046967
0.017613
0.029354
0.041096
0.041096
0.035225
0.003914
0.027397
0.033268
0.031311
0.060665
0.050881
0.062622
0.058708
0.019569
0.011742
0.017613
0.017613
0.037182
0.033268
0.033268
0.043053
0.035225
0.037182
0.011742
0.001957
0.041096
0
32,624
T
C
A
G
G
T
G
A
G
T
T
C
T
T
G
A
C
C
T
C
C
A
C
C
C
A
C
T
T
A
C
C
T
C
C
G
G
G
C
T
G
C
A
C
T
G
C
G
G
T
T
C
C
T
C
A
T
C
C
A
C
T
C
C
T
C
0.046967
0.017613
0.035225
0.019569
0.015656
0.04501
0.005871
0.031311
0.039139
0.035225
0.064579
0.009785
0.02544
0.015656
0.02544
0.037182
0.060665
0.052838
0.04501
0.023483
0.009785
0.011742
0.019569
0.054795
0.031311
0.019569
0.031311
0.050881
0.043053
0.023483
0.013699
0.039139
0
32,625
C
C
A
G
C
G
C
T
G
T
G
C
C
C
G
T
G
G
A
G
G
C
T
G
C
G
T
T
C
C
T
C
C
G
T
G
C
C
T
G
T
T
C
C
A
C
C
T
G
G
G
C
G
G
G
G
T
T
G
A
T
G
G
G
C
T
0.013699
0.017613
0.019569
0.019569
0.02544
0.02544
0.017613
0.019569
0.019569
0.050881
0.056751
0.005871
0.023483
0.04501
0.021526
0.041096
0.074364
0.062622
0.056751
0.027397
0.007828
0.013699
0.009785
0.043053
0.027397
0.021526
0.058708
0.072407
0.048924
0.007828
0.007828
0.037182
0
32,626
C
T
A
C
C
T
A
A
T
A
C
C
T
A
G
A
C
A
G
A
T
G
A
C
A
T
C
A
T
C
T
C
C
G
T
G
T
G
C
A
G
G
T
A
G
G
A
C
A
T
T
A
G
A
T
G
G
T
T
T
C
T
C
T
A
T
0.07045
0.029354
0.033268
0.039139
0.041096
0.033268
0.005871
0.027397
0.054795
0.02544
0.046967
0.035225
0.031311
0.031311
0.035225
0.02544
0.04501
0.031311
0.027397
0.003914
0.005871
0.007828
0.041096
0.035225
0.039139
0.021526
0.031311
0.017613
0.031311
0.033268
0.027397
0.035225
0
32,627
G
G
G
C
T
G
C
C
T
G
T
T
C
G
A
G
A
A
G
G
T
C
A
G
A
G
G
C
G
C
A
A
C
G
A
G
G
A
A
T
T
T
G
G
T
C
T
C
T
G
C
A
A
C
T
G
G
C
A
C
C
C
A
G
T
T
0.02544
0.019569
0.029354
0.027397
0.039139
0.04501
0.011742
0.031311
0.04501
0.019569
0.048924
0.011742
0.019569
0.035225
0.033268
0.04501
0.050881
0.048924
0.058708
0.017613
0.011742
0.009785
0.023483
0.041096
0.033268
0.039139
0.037182
0.031311
0.037182
0.023483
0.009785
0.039139
0
32,628
C
A
A
A
A
A
A
C
A
T
T
T
G
G
C
C
C
T
C
A
T
A
A
A
T
G
T
A
A
A
G
T
C
T
A
C
T
T
T
T
A
T
A
T
T
A
C
C
T
T
T
T
T
C
A
A
A
G
C
A
A
A
C
A
T
T
0.101761
0.033268
0.050881
0.046967
0.052838
0.02544
0.005871
0.035225
0.039139
0.017613
0.033268
0.04501
0.017613
0.050881
0.039139
0.029354
0.02544
0.033268
0.015656
0
0.005871
0
0.02544
0.023483
0.043053
0.021526
0.02544
0.015656
0.02544
0.033268
0.048924
0.033268
0
32,629
G
C
A
G
A
T
C
A
T
A
G
G
T
G
A
A
G
T
T
C
T
G
A
A
A
T
T
T
C
A
C
C
C
C
A
T
C
A
A
T
G
G
T
G
T
A
A
T
G
T
C
C
G
T
A
A
A
A
G
A
G
G
C
T
A
T
0.050881
0.02544
0.041096
0.033268
0.027397
0.027397
0.005871
0.035225
0.041096
0.031311
0.054795
0.019569
0.021526
0.031311
0.029354
0.027397
0.064579
0.054795
0.046967
0.001957
0.003914
0.003914
0.013699
0.043053
0.04501
0.021526
0.031311
0.035225
0.046967
0.019569
0.02544
0.039139
0
32,630
A
A
T
G
G
A
T
G
A
A
T
C
A
G
T
G
A
A
T
T
A
A
T
G
A
A
G
C
T
G
G
A
C
G
C
G
G
C
T
G
G
G
C
C
T
C
A
A
G
G
C
A
G
A
G
T
T
T
T
G
G
G
G
A
G
T
0.037182
0.019569
0.039139
0.029354
0.035225
0.031311
0.007828
0.027397
0.02544
0.050881
0.054795
0.007828
0.021526
0.035225
0.033268
0.041096
0.058708
0.056751
0.04501
0.009785
0.003914
0.005871
0.013699
0.046967
0.029354
0.019569
0.035225
0.041096
0.046967
0.023483
0.02544
0.041096
0
32,631
C
C
A
T
T
T
G
A
A
A
A
A
G
T
T
C
A
A
T
G
A
G
T
T
G
A
T
G
G
T
T
A
C
G
T
T
C
A
G
G
G
T
C
C
G
G
C
C
A
A
C
A
G
T
T
C
T
G
A
T
G
C
C
C
T
T
0.076321
0.035225
0.046967
0.04501
0.043053
0.019569
0.017613
0.023483
0.054795
0.023483
0.029354
0.023483
0.031311
0.048924
0.041096
0.02544
0.035225
0.031311
0.029354
0.009785
0.001957
0.001957
0.013699
0.033268
0.048924
0.023483
0.035225
0.013699
0.037182
0.019569
0.037182
0.043053
0
32,632
G
G
G
G
T
C
C
C
C
G
C
T
A
C
C
T
T
G
C
C
A
G
G
T
G
C
C
C
C
C
C
A
C
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C
C
G
G
A
G
T
C
A
G
C
G
C
A
C
C
C
A
G
G
G
C
T
T
C
C
T
T
G
A
A
T
0.023483
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0.033268
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0.054795
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0.017613
0.023483
0
32,633
T
C
A
C
C
C
A
G
C
T
C
A
T
G
G
T
A
T
C
A
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T
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G
A
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C
C
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C
A
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T
G
G
A
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T
G
A
A
C
A
T
T
T
C
C
A
T
G
G
C
A
T
A
A
G
0.080235
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0.019569
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0.017613
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0
32,634
C
T
T
A
G
C
T
A
G
A
G
A
T
T
C
A
G
A
A
G
G
A
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C
T
C
C
G
A
A
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C
A
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T
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A
T
A
G
T
T
C
C
A
A
T
A
T
T
A
G
T
C
A
T
G
T
0.064579
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0.050881
0
32,635
G
A
A
C
A
A
T
C
T
A
G
A
C
G
C
A
G
T
C
T
G
A
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A
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T
A
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T
A
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C
A
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C
A
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A
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T
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A
A
T
G
A
G
A
G
T
C
A
T
T
T
A
G
A
C
A
A
G
0.058708
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0.050881
0
32,636
G
A
A
T
G
A
A
T
T
T
A
C
G
T
C
A
C
A
C
A
G
G
T
G
G
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T
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C
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C
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T
G
C
A
C
C
A
A
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C
C
C
C
C
A
G
T
G
G
A
G
G
C
A
T
C
T
T
T
C
T
0.052838
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0.037182
0
32,637
G
T
G
C
G
G
A
C
C
C
G
G
C
T
G
G
A
G
G
A
G
C
T
G
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A
T
G
A
C
T
T
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G
A
G
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G
G
T
G
A
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C
A
A
G
T
C
A
T
T
T
G
T
G
G
A
A
T
A
C
A
G
C
0.04501
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0.021526
0.041096
0.039139
0.048924
0.009785
0.015656
0.041096
0
32,638
C
A
G
C
T
C
G
C
C
A
A
G
G
A
A
G
C
A
T
T
C
T
C
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C
C
A
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C
A
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C
T
C
C
A
G
T
G
T
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G
G
C
T
T
C
A
T
C
A
A
G
G
C
T
A
G
T
A
C
A
A
A
G
C
0.035225
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0.033268
0.058708
0.041096
0.009785
0.003914
0.043053
0
32,639
C
A
A
A
G
T
A
A
T
C
A
T
C
A
T
T
G
T
T
T
A
A
A
A
C
T
G
A
G
T
A
T
C
G
A
G
T
C
T
C
T
G
G
T
T
C
T
T
T
G
A
C
C
A
C
T
T
T
C
T
T
C
T
T
C
T
0.076321
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0.02544
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0.023483
0.021526
0.037182
0
32,640
C
T
T
C
C
T
T
G
G
C
C
C
C
T
C
G
A
A
A
C
A
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G
T
C
C
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C
G
G
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G
C
A
C
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C
T
C
A
C
G
T
G
G
G
T
C
C
C
T
A
C
G
C
A
G
G
A
0.005871
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0
0.04501
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0.023483
0
32,641
T
G
A
G
G
T
T
C
C
A
G
C
C
A
A
C
A
G
C
T
T
G
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C
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C
C
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A
G
T
C
A
G
C
T
G
T
G
C
A
C
C
C
T
C
A
T
C
0.029354
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0
0.015656
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0.029354
0.027397
0.037182
0.039139
0.041096
0.013699
0.017613
0.046967
0
32,642
G
C
T
C
A
G
G
C
G
A
C
T
G
C
T
G
T
T
C
A
G
G
T
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T
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C
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A
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C
A
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G
G
C
A
C
C
T
C
C
T
T
T
T
C
C
T
C
A
G
C
T
A
G
C
T
0.078278
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0.054795
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0.07045
0.017613
0.029354
0.017613
0.050881
0.013699
0.013699
0.043053
0
32,643
T
C
T
A
G
G
A
C
A
G
A
A
C
A
G
G
C
T
T
C
A
C
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C
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C
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C
C
A
G
C
A
C
A
T
C
A
T
G
G
G
C
G
A
A
G
T
0.033268
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0.04501
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0.048924
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0.062622
0.052838
0.02544
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0.007828
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0.019569
0.054795
0.04501
0.033268
0.033268
0.04501
0.043053
0.011742
0.009785
0.050881
0
32,644
C
A
C
C
A
G
C
A
G
C
T
T
G
G
T
C
T
G
G
A
G
G
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G
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C
A
T
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C
G
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C
A
C
T
G
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T
G
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C
A
T
C
C
A
C
C
C
T
T
G
G
A
G
C
T
A
G
G
G
T
0.019569
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0.031311
0.005871
0.02544
0.033268
0.04501
0.056751
0.017613
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0.064579
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0.041096
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0.037182
0.037182
0.054795
0.011742
0.021526
0.046967
0
32,645
G
A
T
G
G
C
C
A
G
C
G
G
G
T
C
T
C
G
A
C
T
C
T
T
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G
T
C
C
T
C
A
T
G
C
A
G
T
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G
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C
T
C
T
G
T
A
G
A
A
G
C
C
T
C
C
C
T
G
T
A
A
A
C
0.041096
0.029354
0.027397
0.027397
0.037182
0.052838
0.013699
0.029354
0.041096
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0.043053
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0.052838
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0.017613
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0.029354
0.04501
0.02544
0.021526
0.031311
0.023483
0.029354
0.039139
0.029354
0.027397
0
32,646
G
G
T
T
G
A
G
G
G
C
C
T
C
T
C
C
T
C
C
G
G
T
C
A
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C
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G
C
C
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C
A
G
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C
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C
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A
A
A
C
T
G
G
T
A
C
C
T
T
T
C
T
C
A
G
A
C
A
T
0.046967
0.017613
0.037182
0.013699
0.023483
0.039139
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0.023483
0.048924
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0.064579
0.046967
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0.001957
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0.035225
0.02544
0.02544
0.037182
0.046967
0.011742
0.017613
0.046967
0
32,647
A
G
G
G
C
T
T
C
T
C
T
T
T
C
C
T
C
A
G
G
C
T
G
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C
A
A
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C
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A
C
T
C
C
C
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A
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C
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C
C
C
T
G
T
G
G
T
G
G
G
T
G
A
A
T
G
G
G
A
C
0.050881
0.027397
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0.043053
0.033268
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0.037182
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0.015656
0.037182
0.035225
0.031311
0.023483
0.035225
0.031311
0
32,648
C
C
A
A
G
C
T
C
A
C
C
C
G
C
T
G
G
A
G
T
T
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A
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C
A
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C
C
C
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C
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A
A
A
C
T
G
G
A
A
A
T
A
C
C
C
A
T
C
T
T
C
0.029354
0.031311
0.029354
0.027397
0.033268
0.04501
0.005871
0.021526
0.050881
0.033268
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0.07045
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0.046967
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0.011742
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0.041096
0.037182
0.041096
0.031311
0.04501
0.011742
0.017613
0.033268
0
32,649
C
C
T
C
G
A
A
T
G
T
T
G
G
C
T
G
C
T
G
T
C
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C
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G
A
A
A
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A
C
A
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A
G
T
C
A
T
T
G
T
G
0.039139
0.033268
0.029354
0.035225
0.031311
0.041096
0.001957
0.027397
0.048924
0.02544
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0.07045
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0.041096
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0.046967
0.033268
0.033268
0.033268
0.046967
0.011742
0.023483
0.031311
0
32,650
C
A
A
G
A
G
A
T
G
A
A
C
A
A
A
T
G
T
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C
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A
A
G
T
G
A
G
C
C
C
A
A
G
A
T
G
T
T
C
A
C
0.052838
0.039139
0.031311
0.02544
0.062622
0.031311
0.005871
0.029354
0.041096
0.017613
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0.046967
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0.031311
0.019569
0.050881
0.019569
0.037182
0.021526
0.029354
0.029354
0
32,651
T
G
T
C
C
A
T
A
T
C
C
T
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C
G
T
A
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T
C
A
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T
C
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C
A
G
G
G
G
T
G
0.101761
0.046967
0.041096
0.048924
0.041096
0.02544
0.009785
0.039139
0.039139
0.027397
0.029354
0.04501
0.023483
0.031311
0.033268
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0.033268
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32,652
G
T
A
A
T
C
C
A
A
A
A
G
A
C
A
A
G
A
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A
A
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A
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0
32,653
C
A
A
G
A
T
G
T
T
C
A
T
T
T
T
T
T
C
C
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T
C
A
A
G
G
T
A
G
G
A
G
A
C
T
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C
A
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C
C
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0
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32,654
C
T
T
C
A
T
T
T
G
A
A
C
T
T
T
T
T
C
A
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C
T
T
A
T
T
A
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A
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A
T
G
C
T
G
G
G
A
C
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32,655
A
T
T
A
C
G
G
A
G
G
C
A
G
A
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G
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G
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C
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C
T
T
C
T
G
T
C
C
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C
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32,656
A
G
C
C
C
C
C
C
A
A
A
G
G
G
C
T
C
C
G
G
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C
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A
T
G
A
C
C
C
C
A
T
C
T
C
A
G
A
T
C
C
T
T
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G
G
A
G
A
A
T
G
C
T
G
A
C
T
G
G
A
A
A
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T
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C
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A
G
A
G
T
C
T
G
G
A
A
G
A
A
C
A
A
T
G
G
C
0.093933
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0
32,658
A
G
A
T
T
T
C
A
A
T
G
T
T
T
T
C
C
T
C
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A
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C
A
A
A
G
T
C
G
T
C
A
T
T
C
A
G
G
G
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32,659
T
G
G
C
T
T
C
C
T
C
T
C
T
G
G
C
T
T
C
A
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C
A
T
G
A
C
C
A
G
T
T
T
G
A
C
A
G
G
G
C
C
0.011742
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0
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0
32,660
A
T
G
G
T
C
C
C
A
G
A
T
T
A
C
G
C
C
C
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C
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A
T
G
G
G
G
T
T
T
C
T
G
G
A
C
T
C
C
A
G
G
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0.041096
0.046967
0.011742
0.013699
0.029354
0
32,661
T
G
A
G
T
C
C
A
G
A
A
C
A
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A
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C
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G
A
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T
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A
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A
A
A
A
G
A
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0
32,662
C
A
T
C
A
T
C
C
C
C
G
A
C
A
T
G
G
C
G
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G
A
T
G
C
A
G
A
G
C
A
G
T
G
A
G
A
A
G
C
T
0.076321
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0.029354
0.019569
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0
32,663
G
A
T
T
T
A
C
C
A
A
C
T
G
A
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A
A
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A
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G
G
C
G
A
A
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A
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G
A
G
A
A
A
T
C
A
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0
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0
32,664
A
C
C
T
A
C
G
A
C
A
T
A
C
T
C
C
C
T
T
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A
G
T
G
T
C
G
A
G
T
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A
T
A
C
A
G
T
G
C
A
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0
0.021526
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0.009785
0.041096
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0.048924
0.031311
0
32,665
A
T
T
G
A
C
T
T
C
T
G
G
C
C
A
G
A
A
A
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C
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A
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A
C
A
A
A
C
A
A
A
A
G
A
C
A
A
A
A
T
T
A
T
0.111546
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0.041096
0
32,666
A
G
C
C
A
G
G
A
G
A
C
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A
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C
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C
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A
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G
A
T
A
A
C
T
G
C
T
C
C
T
C
C
A
G
C
A
G
C
T
0.056751
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0.027397
0.02544
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0.029354
0.043053
0.015656
0.031311
0.031311
0
32,667
C
T
T
C
T
A
C
G
T
G
G
G
C
G
A
G
C
C
A
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G
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G
C
T
A
T
G
C
C
A
G
T
C
A
C
A
C
T
G
A
C
A
T
0.033268
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0.062622
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0.035225
0
32,668
C
T
G
A
C
C
T
C
T
G
T
C
C
T
G
A
C
T
T
T
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A
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G
C
A
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C
A
T
C
T
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G
A
A
A
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C
T
C
C
A
G
C
T
T
C
C
0.07045
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0.033268
0.046967
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0.021526
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0.021526
0.048924
0.007828
0.009785
0.046967
0
32,669
C
G
T
G
G
A
A
G
A
C
A
C
A
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T
C
C
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C
T
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C
A
T
C
T
C
G
G
A
C
A
T
C
A
G
C
C
T
0.052838
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0.033268
0.017613
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0.011742
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0.043053
0.04501
0.041096
0.013699
0.007828
0.039139
0
32,670
G
C
C
T
G
C
A
C
C
A
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A
T
T
G
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G
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C
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A
A
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C
G
G
A
A
C
A
T
T
0.017613
0.02544
0.027397
0.013699
0.039139
0.033268
0.021526
0.017613
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0.046967
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0.031311
0.048924
0.050881
0.011742
0.009785
0.033268
0
32,671
C
A
T
C
G
T
C
G
C
T
G
T
C
C
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C
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C
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C
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C
0.017613
0.023483
0.041096
0.019569
0.017613
0.043053
0.009785
0.02544
0.021526
0.048924
0.046967
0.011742
0.027397
0.031311
0.031311
0.029354
0.054795
0.064579
0.066536
0.023483
0.023483
0.021526
0.013699
0.033268
0.035225
0.021526
0.035225
0.046967
0.043053
0.021526
0.019569
0.029354
0
32,672
G
A
G
G
G
G
C
C
C
G
G
C
C
C
A
C
A
G
C
C
T
T
G
T
G
C
T
C
A
C
G
G
C
G
A
C
T
A
T
G
A
C
T
G
T
C
G
C
T
T
G
G
T
T
C
C
T
G
G
T
A
A
C
T
G
A
0.021526
0.013699
0.039139
0.031311
0.037182
0.027397
0.011742
0.015656
0.052838
0.052838
0.031311
0.009785
0.037182
0.031311
0.041096
0.029354
0.058708
0.048924
0.043053
0.021526
0.019569
0.02544
0.013699
0.041096
0.035225
0.039139
0.035225
0.035225
0.039139
0.009785
0.009785
0.041096
0
32,673
G
C
C
C
C
A
G
G
A
G
G
A
G
C
A
G
C
C
C
T
T
G
T
G
C
C
A
C
C
C
A
A
T
A
G
T
A
G
A
A
A
G
G
T
A
A
A
A
A
A
A
A
T
T
T
T
T
T
T
T
T
A
A
A
T
C
0.09589
0.029354
0.050881
0.064579
0.050881
0.017613
0.005871
0.031311
0.039139
0.023483
0.029354
0.054795
0.027397
0.031311
0.039139
0.041096
0.031311
0.027397
0.017613
0
0.003914
0.001957
0.02544
0.015656
0.043053
0.011742
0.031311
0.017613
0.021526
0.023483
0.062622
0.033268
0
32,674
C
C
C
G
G
A
G
T
A
C
T
G
A
G
G
C
C
T
T
G
G
C
C
C
C
A
T
A
A
A
C
C
C
G
G
A
C
A
G
G
G
G
C
C
C
C
G
G
G
G
C
A
T
G
A
G
G
C
G
T
G
C
A
C
C
T
0.029354
0.021526
0.033268
0.009785
0.033268
0.043053
0.011742
0.023483
0.029354
0.037182
0.054795
0.007828
0.013699
0.023483
0.029354
0.04501
0.054795
0.060665
0.113503
0.023483
0.001957
0.005871
0.021526
0.035225
0.02544
0.02544
0.033268
0.054795
0.043053
0.019569
0.009785
0.02544
0
32,675
T
G
T
C
C
T
C
T
C
G
T
T
C
C
A
C
C
C
T
T
A
G
A
G
C
T
G
G
A
A
T
A
C
G
G
C
T
G
G
C
A
T
C
G
G
A
G
A
A
A
C
C
C
T
C
A
C
A
G
A
T
G
A
A
C
T
0.031311
0.019569
0.056751
0.013699
0.031311
0.035225
0.013699
0.019569
0.060665
0.046967
0.048924
0.011742
0.021526
0.027397
0.02544
0.035225
0.062622
0.052838
0.039139
0.011742
0.011742
0.009785
0.015656
0.041096
0.048924
0.027397
0.037182
0.039139
0.039139
0.019569
0.015656
0.029354
0