Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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C
C
C
G
C
C
G
T
A
C
C
C
T
0.029354
0.011742
0.037182
0.009785
0.021526
0.033268
0.011742
0.013699
0.035225
0.043053
0.054795
0
0.007828
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0.103718
0.066536
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0.029354
0.033268
0.029354
0.080235
0.041096
0.015656
0.003914
0.011742
0
34,393
T
G
G
T
G
C
A
G
A
T
G
C
C
T
T
T
G
A
C
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G
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T
A
T
C
A
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A
A
C
T
G
T
G
A
A
G
A
A
0.093933
0.027397
0.041096
0.048924
0.041096
0.021526
0.005871
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0.04501
0.04501
0.060665
0.037182
0.037182
0.035225
0.037182
0.007828
0.003914
0.003914
0.001957
0.017613
0.021526
0.039139
0.013699
0.039139
0.013699
0.033268
0.021526
0.041096
0.048924
0
34,394
T
G
T
T
G
C
A
T
C
T
T
G
A
G
C
A
C
C
A
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A
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G
T
A
T
A
A
A
C
G
T
G
G
T
C
T
C
C
0.131115
0.039139
0.035225
0.072407
0.04501
0.017613
0.011742
0.027397
0.043053
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0.011742
0.064579
0.023483
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0.009785
0
0
0
0.031311
0.02544
0.043053
0.007828
0.023483
0
0.021526
0.02544
0.066536
0.035225
0
34,395
A
C
A
C
C
G
A
G
T
G
C
G
C
G
C
C
G
G
G
C
C
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G
T
T
G
G
A
T
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T
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G
C
G
T
C
T
G
T
C
T
0.017613
0.013699
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0.02544
0.068493
0.086106
0.029354
0.011742
0.003914
0.017613
0
34,396
C
C
T
A
C
T
T
T
G
T
T
G
G
C
A
A
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G
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C
C
T
T
T
C
A
G
A
C
0.07045
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0.050881
0.04501
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0
0.015656
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0.017613
0.029354
0.033268
0.039139
0.023483
0.023483
0.046967
0
34,397
A
T
C
T
T
C
A
G
T
T
A
T
T
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C
T
A
A
G
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G
G
C
C
A
C
T
C
C
C
T
T
G
G
T
C
T
C
T
G
C
0.080235
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0
0.013699
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0.023483
0.029354
0.02544
0.04501
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0.033268
0.046967
0
34,398
C
A
T
G
G
C
A
G
C
C
A
G
G
A
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G
C
C
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A
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C
C
G
G
G
G
C
A
A
G
T
G
C
A
G
A
T
T
0.064579
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0.046967
0.033268
0.019569
0.007828
0.04501
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0.023483
0.011742
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0.043053
0.02544
0.041096
0.037182
0.031311
0.023483
0.037182
0.043053
0
34,399
C
T
G
A
G
G
A
A
T
T
C
C
A
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C
C
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G
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C
A
C
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A
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G
G
A
C
C
A
T
G
G
0.072407
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0.007828
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0.064579
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0.052838
0.013699
0.031311
0.009785
0.021526
0.023483
0.04501
0.048924
0
34,400
T
T
T
T
G
A
A
C
A
G
T
C
T
A
C
A
G
A
A
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G
G
T
T
G
A
A
A
A
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A
A
A
A
C
T
A
A
T
G
T
0.086106
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0.060665
0.056751
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0.029354
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0
0.005871
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0.052838
0.017613
0.029354
0.011742
0.023483
0.021526
0.04501
0.039139
0
34,401
T
T
T
A
T
T
T
T
G
C
C
A
T
T
G
T
C
C
T
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C
A
T
T
A
C
A
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A
T
G
A
A
G
G
G
T
C
A
A
T
0.119374
0.017613
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0.086106
0.031311
0.017613
0
0.031311
0.054795
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0
0.001957
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0.050881
0.027397
0.007828
0.011742
0.029354
0.021526
0.062622
0.050881
0
34,402
T
C
C
T
G
G
T
G
A
A
T
G
C
C
A
T
A
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A
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C
A
A
G
T
A
A
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A
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A
G
A
C
A
G
T
T
A
0.113503
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0.033268
0.019569
0
0.033268
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0
0.001957
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0.009785
0.011742
0.029354
0.021526
0.058708
0.048924
0
34,403
A
A
A
C
T
A
A
G
T
A
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G
A
G
C
T
A
A
A
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C
A
G
A
T
C
T
C
T
T
C
A
A
C
C
A
G
G
T
C
C
0.060665
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0.029354
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0.015656
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0.023483
0.019569
0.031311
0.054795
0
34,404
G
A
A
A
A
A
A
T
A
C
C
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C
A
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T
C
C
A
T
T
C
C
A
T
T
A
G
A
T
T
C
T
G
A
T
0.068493
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0.050881
0.017613
0.017613
0.013699
0.02544
0.027397
0.033268
0.054795
0
34,405
T
C
T
A
A
T
G
G
A
A
T
G
G
A
C
C
A
A
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G
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G
G
T
A
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C
C
T
C
A
G
T
T
0.064579
0.02544
0.039139
0.062622
0.041096
0.015656
0.003914
0.027397
0.056751
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0.050881
0.019569
0.017613
0.013699
0.027397
0.027397
0.029354
0.054795
0
34,406
T
T
T
C
T
T
T
T
T
C
T
T
A
T
T
A
T
G
C
A
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T
C
G
G
C
A
G
A
T
T
T
T
C
C
T
C
A
C
C
G
0.078278
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0.056751
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0.017613
0.005871
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0.050881
0.019569
0.039139
0.027397
0.033268
0.005871
0.035225
0.037182
0
34,407
A
A
C
C
A
A
C
T
G
C
A
T
T
T
T
A
T
T
T
T
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A
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C
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C
T
A
A
G
C
G
T
G
C
T
G
C
T
T
C
T
G
C
A
G
0.084149
0.029354
0.033268
0.058708
0.04501
0.017613
0.005871
0.017613
0.052838
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0.048924
0.019569
0.039139
0.029354
0.033268
0.007828
0.039139
0.035225
0
34,408
T
G
C
T
T
T
A
T
T
T
T
T
C
T
T
A
G
G
T
T
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C
A
A
T
C
A
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C
A
G
T
T
T
G
C
C
C
T
G
G
0.09589
0.027397
0.043053
0.072407
0.021526
0.017613
0.001957
0.039139
0.041096
0.037182
0.023483
0.066536
0.015656
0.037182
0.050881
0.019569
0.02544
0.031311
0.011742
0.001957
0
0.003914
0.037182
0.033268
0.04501
0.013699
0.037182
0.015656
0.023483
0.019569
0.046967
0.043053
0
34,409
G
C
T
G
C
A
G
T
G
G
T
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C
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T
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A
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C
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C
A
G
G
A
A
G
A
C
0.099804
0.037182
0.046967
0.060665
0.035225
0.023483
0
0.031311
0.046967
0.033268
0.023483
0.058708
0.017613
0.043053
0.060665
0.015656
0.02544
0.033268
0.009785
0
0
0.003914
0.029354
0.033268
0.046967
0.013699
0.031311
0.013699
0.019569
0.023483
0.037182
0.04501
0
34,410
A
C
A
C
T
C
T
G
A
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A
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A
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C
0.097847
0.04501
0.048924
0.07045
0.04501
0.011742
0.009785
0.043053
0.041096
0.017613
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0.027397
0.027397
0.048924
0.015656
0.027397
0.007828
0.029354
0.02544
0.056751
0.037182
0
34,411
C
T
T
C
C
A
C
A
A
A
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T
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T
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A
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A
T
T
T
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T
0.093933
0.033268
0.043053
0.048924
0.048924
0.021526
0.005871
0.033268
0.046967
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0.017613
0.023483
0.013699
0.027397
0.023483
0.035225
0.043053
0
34,412
A
C
A
T
G
A
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A
A
G
C
T
T
C
T
G
A
T
C
A
A
A
T
C
T
0.093933
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0.039139
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0
34,413
G
A
A
T
T
C
A
A
T
G
G
A
T
G
G
G
A
C
T
C
T
A
A
T
T
C
G
T
A
T
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T
C
T
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C
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C
A
C
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C
C
C
A
C
T
G
C
C
A
G
C
T
G
C
A
G
C
T
T
C
A
G
T
0.078278
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0
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0
34,414
T
G
T
T
A
A
C
T
T
C
A
C
T
G
A
G
A
A
G
T
G
A
C
T
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G
A
A
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C
C
T
C
G
G
T
G
A
A
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T
C
T
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C
G
T
C
T
T
T
G
T
A
T
A
A
A
C
A
A
A
G
T
T
0.080235
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0.035225
0.048924
0.037182
0
34,415
G
G
C
A
A
C
C
T
T
G
G
A
C
A
G
A
G
G
C
A
C
A
T
T
C
T
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C
T
C
A
G
T
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G
A
C
A
T
T
C
C
A
G
A
A
A
A
G
T
C
T
G
C
C
T
T
G
G
C
T
T
C
G
T
C
0.064579
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0.062622
0.023483
0.041096
0.027397
0.041096
0.015656
0.023483
0.035225
0
34,416
T
G
C
C
A
C
A
G
A
A
C
A
A
G
A
T
G
C
A
G
T
T
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G
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C
C
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A
T
G
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A
A
A
G
A
A
A
A
G
G
G
T
G
G
T
C
T
G
C
A
C
0.041096
0.021526
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0.033268
0.02544
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0.041096
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0.019569
0.058708
0.041096
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0.009785
0.017613
0.033268
0
34,417
C
A
T
C
A
C
A
G
T
C
A
C
A
C
A
C
G
C
G
G
A
T
G
G
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G
A
G
G
G
T
G
T
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G
G
T
G
C
T
G
C
T
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A
G
T
G
A
G
G
G
A
G
A
T
C
C
A
C
T
G
T
C
C
C
0.043053
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0.027397
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0.031311
0.029354
0.033268
0.029354
0.035225
0.02544
0.029354
0.041096
0
34,418
T
T
T
C
C
T
A
T
T
G
T
C
T
G
G
G
T
C
T
G
T
G
G
C
A
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A
C
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C
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C
C
T
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C
A
A
A
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A
T
C
C
C
T
G
T
G
G
G
G
T
T
T
C
T
T
C
A
A
T
0.080235
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0.048924
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0.017613
0.031311
0.019569
0.031311
0.029354
0.039139
0.039139
0
34,419
C
T
C
A
A
T
T
T
G
T
T
A
A
T
G
T
T
A
C
T
T
T
T
C
A
G
A
T
G
G
A
A
C
C
C
A
C
A
A
T
C
A
C
A
A
G
A
A
T
T
G
C
A
T
A
T
G
T
C
T
T
T
T
A
T
T
0.058708
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0
0.009785
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0.015656
0.031311
0.029354
0.027397
0.017613
0.043053
0.048924
0
34,420
A
C
G
A
A
G
C
C
A
G
G
A
A
G
C
T
T
C
A
G
A
T
C
C
T
G
G
G
T
A
A
C
T
T
T
A
G
C
T
T
C
T
A
A
T
G
C
C
T
C
C
T
T
C
T
G
A
G
G
T
G
G
C
A
A
A
0.066536
0.021526
0.054795
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0.001957
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0.046967
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0.041096
0.068493
0.021526
0.027397
0.023483
0.037182
0.021526
0.019569
0.046967
0
34,421
T
T
T
T
T
G
G
C
T
T
T
G
A
T
T
C
T
T
T
C
A
G
T
T
C
T
T
C
A
T
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C
T
T
C
C
A
C
T
T
C
C
A
C
A
G
A
G
A
C
A
A
A
G
C
C
G
A
C
T
C
C
A
G
T
C
0.131115
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0.062622
0.084149
0.033268
0.005871
0
0.031311
0.052838
0.019569
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0.021526
0.039139
0.043053
0.017613
0.017613
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0.011742
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0.003914
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0.019569
0.02544
0.060665
0.015656
0.019569
0.015656
0.02544
0.019569
0.058708
0.043053
0
34,422
T
T
A
C
C
C
A
G
T
G
T
C
T
T
A
C
C
T
C
T
G
C
T
C
T
T
A
A
C
T
C
A
C
A
A
A
T
C
A
C
T
C
T
G
T
C
T
T
T
G
C
T
G
T
T
T
T
G
A
G
A
T
T
T
G
A
0.072407
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0.04501
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0.048924
0.019569
0.003914
0.037182
0.033268
0.02544
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0.007828
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0
0.027397
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0.037182
0.019569
0.027397
0.017613
0.017613
0.02544
0.060665
0.052838
0
34,423
T
G
C
C
T
G
G
T
A
T
T
G
T
C
T
G
T
T
T
A
G
T
T
T
A
T
A
G
T
A
G
G
C
A
T
G
T
T
G
A
A
G
G
T
T
C
A
G
T
A
A
T
T
C
C
T
T
T
C
A
A
A
G
G
A
G
0.093933
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0.007828
0.009785
0.041096
0.054795
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0.064579
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0
0.035225
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0.048924
0.017613
0.031311
0.009785
0.017613
0.033268
0.060665
0.04501
0
34,424
T
G
T
A
T
C
A
T
C
C
A
T
G
G
A
T
T
G
A
T
T
G
G
T
A
G
G
T
T
G
A
C
T
G
G
T
A
G
A
G
A
T
G
G
G
A
C
T
T
C
T
A
T
A
G
T
T
A
T
T
G
G
G
T
G
C
0.058708
0.031311
0.037182
0.07045
0.035225
0.021526
0
0.046967
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0
0.001957
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0.039139
0.029354
0.033268
0.003914
0.021526
0.031311
0.04501
0.052838
0
34,425
A
C
T
C
T
G
T
A
A
A
T
A
G
A
T
C
T
C
T
T
C
T
C
T
C
T
C
T
C
C
T
T
C
T
C
C
T
T
C
T
G
G
A
A
T
G
C
A
T
A
T
T
C
A
A
T
A
A
A
G
G
A
T
A
T
T
0.091977
0.027397
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0.066536
0.031311
0.019569
0.001957
0.041096
0.056751
0.013699
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0.033268
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0.015656
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0.023483
0.017613
0.001957
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0
0.031311
0.029354
0.04501
0.015656
0.035225
0.005871
0.029354
0.035225
0.060665
0.02544
0
34,426
C
C
G
A
A
G
A
A
T
A
C
C
T
T
A
T
T
G
T
C
A
A
C
C
T
G
G
T
C
C
T
T
T
A
T
C
T
T
A
G
T
A
T
C
G
C
A
A
A
A
A
T
C
A
A
C
C
A
T
T
G
G
T
T
T
C
0.09002
0.048924
0.035225
0.052838
0.046967
0.027397
0.015656
0.029354
0.037182
0.019569
0.023483
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0.005871
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0.037182
0.023483
0.033268
0.011742
0.029354
0.011742
0.048924
0.041096
0
34,427
C
T
G
A
C
T
C
C
T
G
T
G
C
A
C
A
G
A
C
A
C
T
T
G
T
T
T
G
C
T
G
C
C
A
T
C
C
T
C
C
T
T
T
G
C
T
T
T
T
C
G
G
G
G
G
C
T
C
G
G
T
C
C
C
T
T
0.088063
0.035225
0.046967
0.029354
0.04501
0.019569
0.021526
0.027397
0.041096
0.039139
0.023483
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0.029354
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0.043053
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0.02544
0.02544
0.019569
0.015656
0.013699
0.017613
0.027397
0.043053
0.021526
0.035225
0.021526
0.027397
0.027397
0.02544
0.039139
0
34,428
C
A
A
A
A
A
T
A
A
G
C
A
A
C
T
A
T
C
T
A
A
T
A
G
T
G
C
A
G
T
A
T
T
T
G
T
G
G
T
G
T
C
A
A
A
T
A
A
C
A
A
T
T
T
A
G
G
G
G
T
G
G
T
A
A
A
0.121331
0.035225
0.033268
0.062622
0.04501
0.023483
0.005871
0.039139
0.037182
0.031311
0.021526
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0.027397
0.021526
0.04501
0.033268
0.04501
0.027397
0.009785
0.003914
0.009785
0
0.035225
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0.043053
0.02544
0.029354
0.009785
0.021526
0.021526
0.043053
0.043053
0
34,429
C
C
T
G
C
A
G
C
T
C
C
C
T
C
A
G
T
G
T
G
G
C
T
T
G
G
A
G
G
A
G
T
T
G
G
C
G
A
A
G
C
T
T
C
C
A
G
A
A
C
A
C
G
C
T
G
G
A
G
G
C
T
G
C
T
C
0.043053
0.021526
0.037182
0.02544
0.039139
0.027397
0.005871
0.021526
0.050881
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0.074364
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0.039139
0.023483
0.043053
0.041096
0.050881
0.005871
0.019569
0.021526
0
34,430
C
A
A
G
C
G
C
G
G
C
G
C
C
G
G
T
T
C
C
G
T
A
C
C
A
C
G
T
G
T
C
C
C
G
G
C
C
A
C
G
A
C
C
C
C
C
G
G
C
G
C
T
G
G
C
C
C
G
C
C
C
C
G
C
G
T
0.005871
0.011742
0.021526
0.011742
0.017613
0.04501
0.027397
0.005871
0.011742
0.033268
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0
0.007828
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0.015656
0.093933
0.054795
0.005871
0.001957
0.017613
0
34,431
A
A
C
T
G
C
A
G
C
A
G
C
C
A
C
A
G
A
G
G
G
T
G
A
G
C
C
T
G
G
A
A
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G
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G
G
C
A
A
C
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T
T
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C
G
G
G
A
G
C
C
T
C
T
T
C
T
C
C
C
T
C
A
C
0.080235
0.04501
0.031311
0.021526
0.046967
0.02544
0.015656
0.02544
0.043053
0.02544
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0.033268
0.017613
0.039139
0.043053
0.041096
0.017613
0.021526
0.02544
0
34,432
T
G
A
A
T
T
T
G
T
G
G
A
T
T
G
C
T
G
T
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C
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C
A
A
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C
T
G
T
A
T
G
G
G
A
G
A
G
G
T
T
C
G
A
C
T
G
A
T
G
A
T
A
A
G
G
G
C
C
C
G
C
0.035225
0.029354
0.046967
0.019569
0.041096
0.027397
0.021526
0.013699
0.04501
0.046967
0.039139
0.031311
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0.037182
0.019569
0.021526
0.037182
0.037182
0.013699
0.027397
0.039139
0
34,433
A
T
T
T
T
C
A
C
T
C
A
G
G
A
A
C
C
T
T
T
G
G
T
G
G
C
A
T
C
C
T
T
C
A
T
G
A
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A
A
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G
G
C
T
G
A
T
C
T
G
G
T
T
G
C
T
C
T
T
C
T
C
A
0.066536
0.031311
0.056751
0.029354
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0.031311
0.001957
0.037182
0.052838
0.023483
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0.023483
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0.04501
0.029354
0.029354
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0.056751
0.019569
0.039139
0.013699
0.037182
0.021526
0.029354
0.048924
0
34,434
C
A
T
C
T
A
A
T
T
T
C
C
T
G
C
G
T
T
T
G
G
A
A
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C
A
T
G
T
T
T
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T
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T
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T
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C
T
A
T
A
A
C
A
A
C
A
C
T
A
T
C
A
G
A
G
C
0.07045
0.031311
0.046967
0.039139
0.039139
0.011742
0.005871
0.029354
0.066536
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0.054795
0.019569
0.039139
0.019569
0.02544
0.007828
0.029354
0.052838
0
34,435
A
G
A
A
G
C
T
G
G
C
T
T
C
A
C
T
G
T
C
A
G
G
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A
A
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G
C
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C
C
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G
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A
C
G
G
G
C
A
C
T
C
C
C
C
T
G
G
C
C
C
T
T
0.052838
0.027397
0.04501
0.023483
0.056751
0.015656
0.015656
0.043053
0.046967
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0.048924
0.027397
0.050881
0.027397
0.029354
0.02544
0.017613
0.04501
0
34,436
T
G
T
T
A
A
C
T
T
C
T
C
C
A
T
C
T
A
G
A
G
A
A
T
G
A
A
A
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A
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A
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T
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C
A
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T
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A
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C
T
T
C
A
A
T
T
G
A
G
T
T
T
C
C
A
C
G
A
G
0.056751
0.041096
0.041096
0.02544
0.043053
0.019569
0.013699
0.039139
0.054795
0.041096
0.021526
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0.023483
0.011742
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0.046967
0.013699
0.033268
0.023483
0.02544
0.02544
0.029354
0.04501
0
34,437
G
G
A
G
A
G
A
C
C
C
C
C
T
G
A
G
A
A
G
G
A
G
A
A
G
A
G
C
T
C
C
C
T
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G
C
C
A
A
G
G
C
T
G
C
G
T
C
C
C
C
C
A
T
A
G
C
A
A
A
A
G
A
G
A
C
0.027397
0.019569
0.04501
0.005871
0.019569
0.033268
0.029354
0.013699
0.037182
0.050881
0.054795
0.005871
0.011742
0.019569
0.033268
0.043053
0.048924
0.043053
0.052838
0.043053
0.007828
0.029354
0.005871
0.056751
0.033268
0.029354
0.046967
0.058708
0.050881
0.003914
0.003914
0.035225
0
34,438
G
G
C
C
T
C
G
C
C
T
C
A
G
C
T
C
C
A
T
C
T
C
G
G
C
C
T
C
T
C
T
G
T
T
G
C
G
A
T
C
C
A
T
C
C
G
A
A
G
G
A
C
G
G
G
C
G
C
G
G
C
C
G
G
T
C
0.015656
0.011742
0.035225
0.001957
0.031311
0.031311
0.013699
0.005871
0.039139
0.060665
0.046967
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0.017613
0.043053
0.062622
0.052838
0.066536
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0.043053
0.029354
0.019569
0.060665
0.068493
0.043053
0.007828
0.001957
0.013699
0
34,439
T
G
G
T
T
C
C
T
G
C
A
A
A
G
G
A
A
T
A
T
C
A
G
G
G
A
C
T
G
G
A
A
T
A
T
T
C
G
T
C
T
T
G
C
C
A
A
C
A
C
G
G
A
C
C
T
T
T
G
C
A
G
G
T
T
C
0.091977
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0.039139
0.076321
0.050881
0.017613
0.009785
0.039139
0.027397
0.013699
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0.046967
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0.04501
0.023483
0.027397
0.023483
0.005871
0.003914
0.005871
0.003914
0.031311
0.017613
0.039139
0.027397
0.023483
0.013699
0.033268
0.031311
0.066536
0.035225
0
34,440
T
T
G
G
C
T
A
A
C
T
C
G
T
G
T
G
C
T
G
T
G
T
G
C
C
T
G
A
A
G
A
G
C
T
C
A
A
T
G
C
T
G
T
G
C
T
C
T
G
G
G
A
G
A
G
A
A
G
C
T
G
A
T
C
A
G
0.046967
0.033268
0.039139
0.076321
0.056751
0.015656
0.007828
0.023483
0.04501
0.039139
0.023483
0.043053
0.031311
0.048924
0.041096
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0.029354
0.02544
0.007828
0.003914
0.007828
0.007828
0.031311
0.031311
0.035225
0.021526
0.023483
0.015656
0.021526
0.017613
0.072407
0.04501
0
34,441
G
A
C
T
C
A
C
A
C
C
A
C
C
C
G
G
C
A
A
G
A
A
C
T
G
C
T
C
A
C
T
A
C
G
G
C
T
C
C
C
T
G
C
C
C
C
A
G
A
A
G
T
C
A
C
A
C
G
G
C
C
G
G
A
C
T
0.035225
0.023483
0.037182
0.015656
0.037182
0.027397
0.017613
0.039139
0.035225
0.023483
0.04501
0.011742
0.037182
0.017613
0.027397
0.046967
0.043053
0.035225
0.060665
0.033268
0.019569
0.019569
0.015656
0.046967
0.033268
0.033268
0.019569
0.031311
0.054795
0.019569
0.015656
0.041096
0
34,442
C
C
C
T
C
T
A
T
T
T
G
C
T
T
G
T
T
C
A
C
C
T
T
C
A
G
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A
G
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G
C
C
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C
A
C
A
C
T
G
A
G
T
C
G
G
T
G
A
T
A
G
A
A
A
T
C
T
C
T
C
C
C
C
T
0.050881
0.021526
0.039139
0.02544
0.060665
0.029354
0.007828
0.029354
0.043053
0.046967
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0.013699
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0.011742
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0.037182
0.031311
0.02544
0.039139
0.027397
0.023483
0.021526
0.019569
0.043053
0
34,443
T
T
G
A
A
G
C
C
G
A
G
A
C
C
A
G
C
C
T
G
C
C
C
G
G
G
C
C
T
G
G
G
C
A
G
G
C
G
G
A
G
C
A
G
G
G
C
C
T
T
G
G
A
C
C
C
C
G
C
G
G
C
G
C
C
G
0.005871
0.003914
0.021526
0
0.011742
0.031311
0.015656
0.005871
0.023483
0.04501
0.046967
0.001957
0.009785
0
0.011742
0.017613
0.046967
0.027397
0.127202
0.119374
0.02544
0.091977
0.001957
0.050881
0.011742
0.041096
0.029354
0.103718
0.058708
0.001957
0.001957
0.007828
0
34,444
G
G
C
C
G
C
C
G
G
C
G
C
C
G
C
C
C
C
G
G
G
A
G
C
T
C
G
G
A
G
G
A
C
C
C
C
G
G
G
C
C
C
G
C
T
C
T
G
C
C
C
A
C
G
C
G
G
A
A
C
T
T
G
G
G
T
0.005871
0.015656
0.015656
0
0.005871
0.033268
0.019569
0.011742
0.017613
0.033268
0.048924
0.001957
0.007828
0.001957
0.005871
0.019569
0.04501
0.033268
0.127202
0.113503
0.039139
0.091977
0.001957
0.048924
0.023483
0.033268
0.02544
0.111546
0.048924
0.001957
0.001957
0.007828
0
34,445
G
G
C
T
T
G
G
C
C
T
C
C
G
A
A
C
C
C
A
C
C
C
C
G
A
C
C
C
C
G
A
C
C
T
C
G
A
C
C
T
C
G
C
G
G
G
A
G
G
G
G
T
G
C
C
A
G
G
C
C
G
C
A
T
C
T
0.007828
0.015656
0.013699
0
0.005871
0.031311
0.013699
0.013699
0.013699
0.04501
0.07045
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0.007828
0.005871
0.007828
0.019569
0.058708
0.048924
0.11546
0.082192
0.033268
0.058708
0.005871
0.064579
0.019569
0.027397
0.031311
0.107632
0.062622
0.001957
0.001957
0.005871
0
34,446
T
G
G
T
T
G
A
T
G
G
T
G
G
G
G
T
G
T
C
T
A
T
T
C
G
A
C
T
T
T
T
A
C
T
T
T
C
T
T
T
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G
T
A
T
C
A
C
T
C
A
G
G
T
G
T
G
A
A
T
C
T
T
T
G
T
0.07045
0.033268
0.039139
0.056751
0.041096
0.02544
0.011742
0.037182
0.041096
0.017613
0.027397
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0.048924
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0.011742
0.009785
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0.027397
0.052838
0.015656
0.019569
0.019569
0.035225
0.019569
0.039139
0.04501
0
34,447
A
G
A
G
T
C
G
G
C
G
T
A
G
C
C
G
T
G
C
G
C
G
C
C
A
G
G
G
A
C
A
G
T
G
G
G
C
G
G
C
A
G
T
T
G
C
A
G
C
C
C
C
A
C
G
G
A
C
G
T
G
G
G
C
A
C
0.003914
0.015656
0.02544
0
0.019569
0.033268
0.035225
0.023483
0.015656
0.041096
0.046967
0
0.007828
0.011742
0.021526
0.052838
0.052838
0.054795
0.088063
0.060665
0.023483
0.056751
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0.043053
0.015656
0.029354
0.050881
0.086106
0.043053
0.013699
0.003914
0.013699
0
34,448
A
G
T
C
C
C
C
A
C
A
G
T
C
G
C
T
C
C
T
C
G
G
C
G
G
G
C
C
G
C
C
C
C
T
C
A
C
T
A
A
A
G
C
C
G
A
G
C
C
C
G
T
C
A
G
C
C
T
G
C
C
C
T
G
C
G
0.007828
0.017613
0.013699
0
0.015656
0.02544
0.043053
0.021526
0.013699
0.058708
0.035225
0
0.007828
0.007828
0.015656
0.048924
0.058708
0.052838
0.080235
0.068493
0.039139
0.060665
0.011742
0.04501
0.013699
0.037182
0.050881
0.093933
0.039139
0.001957
0.001957
0.011742
0
34,449
G
G
A
A
C
G
G
G
G
C
C
A
G
T
G
C
C
G
C
C
T
C
G
G
T
T
A
C
C
T
G
C
T
G
T
G
C
C
G
G
T
C
G
G
C
T
C
C
C
G
G
C
C
T
G
G
G
C
C
C
C
G
C
G
G
C
0.011742
0.019569
0.013699
0.003914
0.009785
0.035225
0.017613
0.007828
0.011742
0.048924
0.039139
0
0.009785
0.009785
0.011742
0.017613
0.046967
0.037182
0.103718
0.113503
0.021526
0.109589
0.009785
0.037182
0.021526
0.021526
0.027397
0.107632
0.04501
0.013699
0.003914
0.011742
0
34,450
T
C
G
C
T
T
T
T
T
T
T
A
T
G
A
A
C
T
T
A
G
A
A
G
G
G
A
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G
A
A
G
C
G
C
A
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G
C
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G
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T
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G
G
T
C
C
A
T
G
G
G
C
A
G
C
C
A
T
G
G
G
C
T
0.033268
0.02544
0.029354
0.013699
0.031311
0.037182
0.001957
0.037182
0.021526
0.048924
0.054795
0.009785
0.011742
0.031311
0.029354
0.035225
0.060665
0.058708
0.054795
0.027397
0.009785
0.011742
0.023483
0.046967
0.035225
0.027397
0.033268
0.046967
0.056751
0.017613
0.003914
0.033268
0
34,451
G
G
G
C
G
G
G
C
C
T
A
G
A
A
A
A
A
G
C
A
C
T
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C
C
G
A
T
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G
G
C
T
G
T
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G
G
T
C
A
T
C
A
A
T
G
A
A
G
T
C
C
T
C
A
C
T
T
C
C
G
G
T
0.035225
0.02544
0.033268
0.013699
0.031311
0.033268
0.001957
0.035225
0.017613
0.043053
0.054795
0.007828
0.009785
0.031311
0.035225
0.037182
0.058708
0.064579
0.062622
0.027397
0.009785
0.015656
0.017613
0.041096
0.033268
0.02544
0.039139
0.058708
0.052838
0.013699
0.003914
0.029354
0
34,452
G
T
C
C
T
C
C
A
C
G
C
C
G
G
T
G
A
G
G
C
A
C
A
G
C
A
G
T
T
C
C
A
T
C
T
C
C
C
T
C
T
C
C
A
G
G
C
T
C
T
C
G
A
C
T
A
C
C
G
C
G
G
C
C
A
A
0.013699
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0.066536
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0
34,453
C
A
T
C
A
G
C
A
C
A
T
G
C
T
C
A
G
C
A
C
A
C
A
C
T
T
G
G
C
A
C
A
C
T
C
G
T
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T
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G
C
A
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A
C
T
A
C
A
C
A
T
G
C
T
C
A
G
C
A
C
A
C
G
G
0.005871
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0.015656
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0.103718
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0.04501
0.04501
0
0.084149
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0.07045
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0.033268
0.109589
0.017613
0
0.011742
0.007828
0.058708
0
34,454
C
A
T
C
A
G
A
C
A
A
C
A
A
C
G
C
A
G
A
G
T
G
C
T
G
C
A
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T
C
T
G
T
G
C
T
A
C
C
T
T
G
G
C
G
A
A
C
T
G
T
T
C
A
G
A
A
G
G
A
A
C
A
G
A
C
0.088063
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0.041096
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0.043053
0.021526
0.021526
0.019569
0.031311
0.04501
0
34,455
C
G
C
T
C
C
C
C
A
C
G
G
C
G
C
A
C
T
C
C
A
C
C
C
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G
C
C
G
G
C
C
C
C
G
T
G
C
C
A
C
A
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C
C
T
T
C
A
G
A
C
C
T
C
C
A
C
A
C
C
G
G
G
C
A
0.021526
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0.017613
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0.035225
0.072407
0.054795
0.009785
0.003914
0.023483
0
34,456
C
C
G
G
T
C
G
T
G
G
G
C
G
G
G
A
A
G
A
A
G
A
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G
G
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C
C
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G
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C
C
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T
C
C
T
G
C
A
G
G
A
C
T
C
C
A
A
G
G
T
C
A
T
C
0.011742
0.007828
0.027397
0.001957
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0.04501
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0.013699
0.033268
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0.07045
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0.064579
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0.027397
0.033268
0.056751
0.064579
0.043053
0.003914
0.001957
0.023483
0
34,457
T
G
A
A
C
G
G
G
G
C
T
G
G
T
T
A
T
C
C
T
C
T
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A
T
T
C
C
G
A
A
A
T
G
G
C
G
G
G
A
T
C
T
C
A
A
C
C
A
C
C
A
G
A
G
A
A
T
T
C
T
A
C
A
G
C
0.031311
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0.011742
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0.033268
0.062622
0.011742
0.033268
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0.011742
0.019569
0.039139
0.021526
0.041096
0.066536
0.027397
0.017613
0.019569
0.02544
0
34,458
G
A
A
T
G
C
G
C
C
C
C
C
T
G
G
G
T
C
C
C
G
A
G
A
A
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C
T
C
A
G
A
C
G
A
G
A
A
A
G
A
A
A
G
G
T
G
G
G
T
A
A
C
C
T
C
C
T
T
C
C
T
G
A
T
T
0.09589
0.033268
0.046967
0.068493
0.035225
0.015656
0.007828
0.031311
0.060665
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0.023483
0.029354
0.054795
0.011742
0.019569
0.013699
0.021526
0.023483
0.052838
0.041096
0
34,459
A
G
A
T
C
C
A
C
G
T
T
T
G
T
G
T
A
G
G
A
T
G
G
A
A
T
G
C
A
G
A
G
T
T
C
T
G
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T
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C
T
G
A
G
A
G
A
G
C
T
G
C
C
A
G
G
A
A
C
A
T
T
T
T
A
0.033268
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0
0.009785
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0.058708
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0.04501
0
34,460
G
A
A
T
T
T
T
C
A
A
T
G
C
C
A
G
C
T
T
G
C
A
C
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A
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A
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T
C
C
T
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G
A
C
A
T
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C
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C
T
G
T
A
A
G
T
C
C
T
C
A
A
T
G
C
G
A
T
T
A
0.07045
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0.04501
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0.011742
0.011742
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0.019569
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0.013699
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0.04501
0.02544
0.046967
0.027397
0.039139
0.013699
0.033268
0.039139
0
34,461
T
T
T
C
C
T
C
C
T
T
T
T
G
T
A
C
T
C
C
A
T
A
A
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G
C
T
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T
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G
A
G
C
G
C
C
T
C
A
T
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A
T
C
G
A
T
C
C
C
A
C
A
C
A
G
A
C
T
G
G
G
0.021526
0.027397
0.039139
0.003914
0.048924
0.037182
0.009785
0.021526
0.037182
0.035225
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0.023483
0.023483
0.033268
0.046967
0.054795
0.048924
0.054795
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0.015656
0.011742
0.058708
0.027397
0.027397
0.029354
0.04501
0.050881
0.015656
0.007828
0.031311
0
34,462
C
A
G
G
C
G
G
G
G
C
T
T
G
G
C
C
C
T
C
T
T
C
C
T
T
C
C
C
T
T
T
T
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C
A
T
C
T
G
C
G
T
T
G
T
C
A
G
C
T
C
A
G
C
C
A
C
C
T
G
C
C
C
C
T
G
0.021526
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0.035225
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0.048924
0.029354
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0.015656
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0.04501
0.060665
0.052838
0.054795
0.017613
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0.058708
0.023483
0.023483
0.046967
0.052838
0.052838
0.011742
0.005871
0.023483
0
34,463
T
T
C
C
T
T
T
G
G
G
A
T
G
T
A
C
T
G
C
A
T
G
G
T
G
T
T
C
T
T
G
G
C
G
G
T
G
A
G
T
C
T
G
T
T
T
C
T
C
C
C
G
G
G
C
T
T
G
C
T
T
T
T
C
G
T
0.041096
0.029354
0.027397
0.011742
0.037182
0.02544
0.007828
0.033268
0.033268
0.037182
0.054795
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0.04501
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0.033268
0.021526
0.039139
0.04501
0.050881
0.011742
0.017613
0.027397
0
34,464
T
G
G
G
C
A
C
C
T
C
G
A
G
G
C
C
T
C
C
T
C
G
C
A
C
T
C
C
C
C
C
C
T
A
A
C
A
C
T
G
T
A
G
T
T
C
T
G
T
G
A
C
A
G
G
A
T
C
T
C
T
G
C
G
A
G
0.017613
0.017613
0.027397
0.013699
0.035225
0.035225
0.007828
0.029354
0.039139
0.04501
0.062622
0
0.02544
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0.046967
0.064579
0.054795
0.050881
0.009785
0.013699
0.007828
0.017613
0.064579
0.021526
0.02544
0.046967
0.04501
0.046967
0.017613
0.011742
0.037182
0
34,465
C
C
G
T
G
C
C
A
A
A
A
C
C
C
A
A
G
C
C
A
C
A
T
G
T
G
T
C
A
G
A
C
C
A
T
A
A
C
C
G
C
C
T
C
C
T
T
C
A
C
T
T
G
G
C
C
A
G
T
A
A
G
T
A
G
T
0.039139
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0.04501
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0.039139
0.013699
0.019569
0.058708
0.033268
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0.046967
0.031311
0.029354
0.039139
0.050881
0.011742
0.007828
0.027397
0
34,466
A
C
C
T
G
T
T
G
T
T
G
T
T
G
T
A
A
T
A
T
T
C
C
A
G
G
T
A
G
A
A
T
C
T
C
T
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G
G
C
C
G
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G
A
C
A
G
T
T
C
C
T
C
C
A
C
G
C
G
G
C
G
G
A
0.021526
0.02544
0.031311
0.027397
0.041096
0.021526
0.007828
0.021526
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0.052838
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0.031311
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0.088063
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0.029354
0.04501
0.029354
0.050881
0.052838
0.046967
0.005871
0.005871
0.02544
0
34,467
G
G
T
C
C
C
T
T
C
C
C
A
G
C
C
C
C
C
G
C
G
G
C
C
T
C
A
C
T
C
T
C
C
C
G
G
C
A
C
C
C
A
A
A
T
G
T
G
T
C
T
G
T
G
G
T
G
G
C
C
G
C
G
G
C
T
0.009785
0.011742
0.021526
0.013699
0.027397
0.048924
0.021526
0.009785
0.043053
0.041096
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0.039139
0.060665
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0.074364
0.052838
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0.062622
0.027397
0.050881
0.027397
0.04501
0.068493
0.005871
0.003914
0.02544
0
34,468
G
A
G
A
C
C
C
C
A
G
C
T
T
C
C
C
A
G
G
C
T
C
C
G
G
T
G
G
G
G
A
G
T
G
G
G
G
C
C
A
G
G
C
G
A
G
G
G
T
G
C
C
C
T
G
A
C
G
A
G
G
G
T
G
G
C
0.011742
0.009785
0.017613
0.003914
0.027397
0.029354
0.017613
0.013699
0.039139
0.043053
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0.013699
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0.041096
0.074364
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0.091977
0.043053
0.011742
0.037182
0.001957
0.064579
0.017613
0.033268
0.033268
0.09002
0.058708
0.003914
0
0.013699
0
34,469
T
G
G
G
G
C
C
T
A
C
A
G
C
C
C
A
G
A
G
A
A
G
G
T
G
C
C
C
C
C
T
G
T
G
C
G
C
C
A
T
C
G
G
A
C
A
C
C
G
C
C
G
G
C
T
T
T
C
A
C
C
C
T
G
G
C
0.011742
0.005871
0.029354
0.001957
0.033268
0.041096
0.009785
0.007828
0.027397
0.04501
0.068493
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0.013699
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0.064579
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0.009785
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0.019569
0.021526
0.037182
0.09002
0.039139
0.017613
0.003914
0.023483
0
34,470
G
A
C
T
C
G
C
C
G
C
C
C
T
G
A
G
A
T
C
T
C
C
C
A
G
G
C
T
G
G
G
C
C
C
A
C
G
C
A
G
G
G
A
G
A
A
G
T
G
A
T
C
C
C
A
A
C
A
G
G
C
T
G
T
G
A
0.029354
0.021526
0.019569
0.003914
0.027397
0.039139
0.007828
0.019569
0.037182
0.037182
0.066536
0
0.013699
0.005871
0.013699
0.037182
0.064579
0.056751
0.113503
0.046967
0.021526
0.009785
0.001957
0.072407
0.027397
0.035225
0.021526
0.056751
0.074364
0
0.001957
0.015656
0
34,471
T
G
C
C
G
G
G
G
C
G
G
C
C
G
C
A
C
G
A
G
C
T
G
T
C
G
C
G
G
C
T
G
C
G
G
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G
C
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G
C
G
G
G
C
C
G
C
C
C
T
C
A
T
C
C
G
C
C
T
0
0.007828
0.003914
0
0.005871
0.007828
0.013699
0.005871
0.003914
0.033268
0.02544
0
0.001957
0.005871
0.007828
0.017613
0.02544
0.015656
0.162427
0.172211
0.027397
0.166341
0
0.039139
0.003914
0.007828
0.033268
0.183953
0.019569
0
0
0.001957
0
34,472
G
C
T
G
C
T
C
C
C
G
C
A
G
G
G
C
C
T
C
G
G
G
C
G
C
C
C
C
C
A
G
C
T
C
C
T
C
C
C
A
G
T
A
C
T
G
C
C
G
C
G
G
C
A
G
G
C
A
G
G
G
C
T
C
G
G
0.001957
0.009785
0.013699
0.001957
0.015656
0.033268
0.019569
0.011742
0.021526
0.062622
0.058708
0.003914
0.015656
0.02544
0.015656
0.035225
0.084149
0.060665
0.101761
0.043053
0.013699
0.037182
0.009785
0.046967
0.009785
0.021526
0.068493
0.084149
0.043053
0.013699
0
0.015656
0
34,473
T
T
C
C
C
G
C
A
G
G
G
A
C
C
G
C
C
G
G
T
G
G
C
G
T
C
T
G
C
G
G
C
C
C
C
A
G
G
A
G
G
A
G
C
T
C
G
T
C
C
G
C
C
A
G
C
C
C
C
C
A
G
G
A
G
T
0.021526
0.017613
0.035225
0.001957
0.013699
0.031311
0.02544
0.011742
0.043053
0.046967
0.054795
0.001957
0.003914
0.007828
0.013699
0.029354
0.048924
0.035225
0.076321
0.066536
0.027397
0.060665
0.003914
0.068493
0.031311
0.033268
0.037182
0.074364
0.052838
0
0.009785
0.013699
0
34,474
C
A
C
G
C
C
G
T
G
G
C
C
C
C
C
G
G
G
C
T
G
C
C
T
G
G
C
C
G
T
C
T
C
C
C
T
T
T
G
T
G
T
T
A
C
C
T
T
C
T
T
T
G
C
C
G
G
G
G
A
G
T
C
C
C
T
0.033268
0.015656
0.037182
0.001957
0.011742
0.035225
0.021526
0.017613
0.013699
0.035225
0.056751
0.001957
0.001957
0.017613
0.02544
0.035225
0.039139
0.035225
0.074364
0.074364
0.02544
0.076321
0.005871
0.041096
0.017613
0.027397
0.054795
0.09589
0.035225
0.007828
0.011742
0.015656
0
34,475
G
C
C
C
T
G
C
G
G
C
A
G
C
G
T
G
A
A
C
A
G
G
T
G
C
T
G
G
T
C
C
A
C
G
T
G
C
T
G
G
G
G
A
G
A
G
G
A
G
G
G
G
G
G
C
G
T
G
A
C
C
T
C
G
G
T
0.015656
0.011742
0.02544
0.005871
0.015656
0.031311
0.037182
0.005871
0.031311
0.041096
0.050881
0
0.015656
0.009785
0.017613
0.041096
0.056751
0.043053
0.107632
0.066536
0.021526
0.046967
0.005871
0.041096
0.02544
0.031311
0.04501
0.086106
0.041096
0.005871
0
0.019569
0