Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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C
A
G
A
A
G
C
A
G
0.050881
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0.062622
0.029354
0
0.023483
0.04501
0.04501
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0
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0
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0.050881
0.015656
0.046967
0.029354
0.037182
0.015656
0.013699
0.037182
0
35,993
C
T
G
G
G
C
T
T
G
G
G
G
C
T
T
C
T
C
C
A
G
A
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C
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C
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A
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G
A
G
T
A
G
C
A
G
G
A
G
A
G
T
G
T
T
C
T
T
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0.04501
0.02544
0.02544
0.021526
0.054795
0.013699
0.017613
0.033268
0
35,994
T
T
C
A
C
A
C
C
T
C
C
C
T
G
A
G
C
T
C
C
A
C
C
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C
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A
A
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A
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T
C
T
C
G
G
T
A
T
G
G
C
T
G
A
A
G
T
C
A
C
A
A
C
T
T
C
C
C
A
A
T
0.037182
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0.021526
0.041096
0.013699
0.011742
0.060665
0
35,995
T
T
T
G
C
A
A
C
T
C
C
T
C
A
A
A
A
C
T
G
G
G
A
C
C
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C
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C
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T
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A
A
G
G
G
T
T
T
C
T
C
T
C
C
A
C
A
G
T
G
C
T
G
0.048924
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0
0.035225
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0
0.023483
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0.021526
0.048924
0.029354
0.035225
0.015656
0.019569
0.046967
0
35,996
T
T
C
A
G
G
T
A
G
T
T
G
G
C
A
A
G
G
A
G
C
C
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C
T
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C
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G
A
G
T
G
C
T
T
C
T
G
T
A
G
A
A
G
T
G
C
A
0.029354
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0
0.005871
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0.039139
0.021526
0.056751
0.02544
0.035225
0.013699
0.009785
0.04501
0
35,997
G
G
C
A
C
T
T
C
T
A
C
A
G
A
A
G
C
A
C
T
C
T
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C
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C
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C
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G
C
T
C
C
T
T
G
C
C
A
A
C
T
A
C
C
T
G
A
C
0.029354
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0
0.005871
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0.039139
0.021526
0.056751
0.02544
0.035225
0.013699
0.009785
0.04501
0
35,998
T
T
C
T
T
C
C
A
C
A
G
A
A
A
C
G
C
T
C
T
C
T
G
C
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A
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G
C
G
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C
C
C
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C
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C
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T
G
C
T
C
C
A
C
A
C
C
A
G
C
A
A
C
C
T
G
C
0.064579
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0.02544
0
0
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0.02544
0.019569
0.015656
0.035225
0.021526
0.019569
0.052838
0
35,999
G
A
A
G
G
A
T
G
A
A
G
A
G
T
C
A
T
C
T
T
C
T
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A
A
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A
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C
A
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T
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C
T
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C
A
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G
T
C
A
C
A
T
G
T
T
A
A
T
A
C
T
T
C
C
A
C
0.041096
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0
0.001957
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0.046967
0.021526
0.033268
0.027397
0.02544
0.037182
0.015656
0.048924
0
36,000
A
G
C
T
T
T
G
C
G
G
C
T
G
A
A
G
G
C
T
T
T
C
C
C
A
C
A
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C
G
C
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C
A
C
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C
A
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C
T
T
C
T
C
T
C
C
A
C
T
A
T
G
A
A
T
T
C
G
0.048924
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0.04501
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0.043053
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0.007828
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0.054795
0.013699
0.048924
0.031311
0.041096
0.019569
0.02544
0.035225
0
36,001
T
C
A
G
A
G
A
G
T
T
C
A
T
A
C
T
G
G
A
G
A
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C
C
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C
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C
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T
G
G
G
A
A
A
T
C
G
T
T
T
A
G
T
C
A
G
A
T
0.062622
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0.017613
0.005871
0.04501
0.04501
0.021526
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0.017613
0
0.007828
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0.062622
0.013699
0.033268
0.031311
0.035225
0.023483
0.027397
0.04501
0
36,002
G
C
A
A
A
A
G
C
T
A
C
A
G
T
C
T
C
A
A
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G
A
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A
A
A
A
G
C
C
T
T
A
T
G
A
A
T
G
T
C
G
A
G
0.052838
0.031311
0.037182
0.037182
0.054795
0.015656
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0.048924
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0.035225
0.019569
0.041096
0.013699
0.023483
0.052838
0
36,003
A
G
A
G
G
T
A
T
C
T
T
C
T
G
A
G
C
A
G
A
G
C
A
T
T
T
T
T
G
T
A
G
C
A
G
G
A
G
T
G
T
C
A
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A
G
G
T
C
A
G
G
A
C
T
C
T
C
A
T
G
G
C
A
G
T
0.04501
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0.035225
0.001957
0.029354
0.043053
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0.007828
0.066536
0.031311
0.037182
0.052838
0.056751
0.035225
0.001957
0
0
0.005871
0.052838
0.046967
0.023483
0.043053
0.029354
0.037182
0.023483
0.011742
0.048924
0
36,004
G
G
G
G
T
G
G
G
C
C
T
T
C
T
T
G
G
G
A
G
A
C
A
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C
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G
T
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C
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C
C
T
G
A
G
T
C
T
C
T
C
T
T
T
G
T
A
T
A
T
T
0.031311
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0.068493
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0.035225
0.04501
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0.064579
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0.04501
0.041096
0.021526
0.035225
0.023483
0.043053
0.019569
0.019569
0.041096
0
36,005
C
T
G
T
G
A
A
T
G
T
G
G
G
A
A
A
T
C
C
T
T
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C
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C
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T
C
A
T
C
A
G
A
G
A
G
T
T
C
A
C
A
G
T
G
C
0.072407
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0.037182
0.046967
0.011742
0.005871
0.043053
0.04501
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0.043053
0.041096
0.027397
0
0.003914
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0.046967
0.058708
0.019569
0.017613
0.017613
0.043053
0.005871
0.027397
0.056751
0
36,006
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
G
C
A
A
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T
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A
A
T
A
T
A
A
A
A
A
T
T
A
G
C
C
G
G
G
C
C
0.050881
0.013699
0.046967
0.031311
0.027397
0.027397
0.001957
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0.033268
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0.054795
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0.011742
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0.033268
0.037182
0.023483
0.048924
0.041096
0.041096
0.013699
0.015656
0.039139
0
36,007
A
G
A
T
T
T
C
C
C
A
C
A
T
T
C
T
C
T
A
C
A
C
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C
A
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A
G
G
C
C
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T
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C
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C
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A
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T
G
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G
A
A
C
A
A
G
C
T
G
A
T
G
G
C
T
A
A
T
A
A
T
0.050881
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0.052838
0.031311
0.050881
0.019569
0.005871
0.033268
0.04501
0.037182
0.037182
0.02544
0.043053
0.033268
0.02544
0.056751
0.048924
0.039139
0.023483
0.001957
0.013699
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0.04501
0.023483
0.021526
0.021526
0.039139
0.009785
0.033268
0.052838
0
36,008
T
G
C
A
G
C
T
T
T
T
G
C
C
G
A
T
G
C
A
C
A
A
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T
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C
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T
A
A
T
G
C
T
G
C
A
G
G
C
C
T
C
A
G
A
A
G
0.080235
0.039139
0.04501
0.048924
0.050881
0.017613
0.005871
0.029354
0.039139
0.021526
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0.046967
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0.017613
0.009785
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0.001957
0.011742
0.019569
0.041096
0.013699
0.039139
0.019569
0.035225
0.021526
0.056751
0.035225
0
36,009
C
A
G
A
G
C
T
G
G
A
A
A
G
A
A
A
T
G
A
T
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C
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C
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G
C
C
T
T
T
C
T
C
C
A
G
T
G
T
G
A
A
T
C
C
0.052838
0.021526
0.043053
0.058708
0.050881
0.015656
0.007828
0.033268
0.043053
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0.078278
0.009785
0.023483
0.017613
0.043053
0.023483
0.029354
0.058708
0
36,010
A
A
A
A
A
T
G
C
T
C
T
G
T
G
C
T
G
G
G
A
T
C
A
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C
T
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C
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A
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A
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C
A
C
C
C
A
T
T
C
T
G
A
A
A
C
A
G
A
C
A
C
0.09002
0.037182
0.052838
0.043053
0.037182
0.019569
0
0.04501
0.064579
0.027397
0.011742
0.039139
0.029354
0.048924
0.035225
0.019569
0.039139
0.04501
0.019569
0
0
0
0.027397
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0.060665
0.013699
0.021526
0.009785
0.027397
0.029354
0.037182
0.039139
0
36,011
G
C
C
C
A
G
A
G
G
C
A
C
A
C
A
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C
A
A
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C
C
C
A
G
C
A
C
T
G
A
G
C
C
C
C
A
G
G
A
G
0.013699
0.017613
0.031311
0.005871
0.029354
0.023483
0.009785
0.019569
0.027397
0.048924
0.066536
0
0.021526
0.019569
0.019569
0.041096
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0.046967
0.097847
0.029354
0.013699
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0.050881
0.031311
0.023483
0.052838
0.062622
0.056751
0
0.003914
0.027397
0
36,012
G
C
T
T
C
A
G
C
T
G
C
C
C
C
C
A
C
T
C
C
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C
G
T
C
A
C
T
T
G
C
T
C
C
T
0.043053
0.021526
0.033268
0.031311
0.035225
0.041096
0.015656
0.015656
0.033268
0.043053
0.052838
0.019569
0.029354
0.029354
0.02544
0.035225
0.072407
0.062622
0.048924
0.007828
0.003914
0
0.015656
0.02544
0.027397
0.031311
0.02544
0.04501
0.037182
0.019569
0.033268
0.039139
0
36,013
C
G
C
C
G
G
A
G
C
T
A
G
A
G
A
C
G
C
C
C
T
C
G
A
G
G
C
T
C
T
G
C
C
C
G
T
C
C
C
C
A
T
C
C
T
C
G
G
G
G
T
G
C
G
G
C
C
T
C
T
T
G
G
T
T
T
0.001957
0.003914
0.023483
0
0.009785
0.023483
0.023483
0.013699
0.021526
0.052838
0.066536
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0.013699
0.011742
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0.029354
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0.035225
0.048924
0.097847
0.054795
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0
0.013699
0
36,014
A
G
G
G
T
C
A
C
C
T
G
G
A
T
G
C
T
T
G
C
C
C
T
G
C
T
G
T
T
G
G
A
C
C
T
G
C
T
C
A
C
T
G
G
G
G
G
C
A
T
C
T
G
C
A
C
T
C
A
G
G
C
T
T
C
T
0.011742
0.023483
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0.029354
0.027397
0.050881
0.037182
0.060665
0.005871
0.013699
0.039139
0
36,015
T
G
C
T
T
C
C
A
T
T
T
C
C
T
C
C
C
T
G
C
A
C
C
T
G
A
A
G
A
G
G
C
C
G
C
T
G
T
G
T
A
G
A
G
G
G
C
A
G
A
G
G
T
C
C
T
C
A
G
A
A
G
A
C
C
T
0.017613
0.013699
0.019569
0.011742
0.027397
0.037182
0.015656
0.019569
0.035225
0.058708
0.056751
0.005871
0.005871
0.023483
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0.078278
0.056751
0.076321
0.021526
0.005871
0.027397
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0.027397
0.027397
0.056751
0.052838
0.04501
0.007828
0.003914
0.027397
0
36,016
A
A
G
A
G
T
T
G
A
A
A
C
A
A
A
A
T
T
C
A
G
C
T
T
T
C
A
T
T
A
A
T
C
A
T
G
A
G
A
A
A
A
A
T
G
G
A
G
C
A
G
A
T
G
G
G
A
A
G
C
A
C
T
G
T
G
0.064579
0.050881
0.056751
0.027397
0.041096
0.033268
0.003914
0.052838
0.050881
0.02544
0.041096
0.019569
0.013699
0.033268
0.041096
0.031311
0.037182
0.02544
0.021526
0
0
0
0.021526
0.054795
0.060665
0.015656
0.013699
0.003914
0.029354
0.031311
0.033268
0.064579
0
36,017
T
A
T
G
T
G
T
C
C
G
C
C
G
A
T
G
C
A
C
T
A
C
A
A
G
T
T
G
A
G
A
T
T
G
C
T
G
C
C
G
G
A
A
G
G
A
T
T
T
C
C
C
A
C
A
G
T
C
A
C
T
A
C
A
T
C
0.037182
0.017613
0.043053
0.035225
0.039139
0.021526
0.009785
0.035225
0.039139
0.039139
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0.007828
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0.048924
0.019569
0.04501
0.017613
0.043053
0.019569
0.011742
0.060665
0
36,018
T
T
T
T
C
C
C
T
G
T
A
T
G
C
G
T
G
A
C
A
A
G
T
T
G
T
C
T
G
T
C
T
C
C
A
A
A
T
T
T
C
T
G
T
T
T
T
T
A
T
A
A
G
G
A
C
A
A
C
A
G
T
C
A
T
G
0.080235
0.039139
0.039139
0.062622
0.054795
0.027397
0.005871
0.02544
0.046967
0.021526
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0.066536
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0.052838
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0.033268
0.041096
0.015656
0.001957
0.001957
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0.023483
0.02544
0.037182
0.035225
0.009785
0.017613
0.029354
0.019569
0.050881
0.035225
0
36,019
T
C
T
T
G
A
A
C
A
G
C
T
G
G
A
A
G
T
C
T
G
G
A
G
T
C
T
C
C
A
G
G
T
G
G
G
C
C
T
G
G
C
A
C
G
T
C
A
G
C
G
T
C
A
C
A
T
T
G
G
C
C
A
A
G
C
0.003914
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0.021526
0.037182
0.039139
0.07045
0.041096
0.005871
0.003914
0.043053
0
36,020
T
G
C
A
G
G
G
A
G
T
G
C
G
G
C
A
A
G
G
C
C
T
T
C
C
G
C
G
C
G
C
A
C
T
C
G
C
A
G
C
T
C
A
T
C
C
A
C
C
A
C
C
A
G
G
A
G
A
C
A
C
A
C
A
G
A
0.001957
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0.019569
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0.029354
0.021526
0.017613
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0
0.005871
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0.060665
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0.066536
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0.029354
0.011742
0.082192
0.093933
0.039139
0.009785
0.001957
0.011742
0
36,021
C
T
C
C
C
G
A
C
C
C
C
C
G
T
C
G
G
G
G
A
C
T
C
C
G
C
T
C
G
C
T
G
T
A
G
T
C
C
C
C
G
C
A
G
G
G
C
G
G
G
C
A
C
C
C
C
A
G
C
C
G
G
A
A
G
C
0.003914
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0
0.015656
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0
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0.062622
0.076321
0.046967
0.105675
0.007828
0.043053
0.023483
0.021526
0.060665
0.099804
0.023483
0.019569
0
0.009785
0
36,022
G
G
A
C
C
T
C
A
C
A
C
A
G
T
T
G
A
G
T
C
C
G
G
G
G
G
T
G
G
T
T
C
T
G
G
A
T
C
C
G
C
T
C
C
G
G
A
C
A
G
G
G
G
T
C
A
C
A
C
A
C
G
G
G
T
C
0.003914
0.017613
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0
0.019569
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0.013699
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0.013699
0.031311
0.04501
0.076321
0.064579
0.001957
0.001957
0.011742
0
36,023
T
C
C
T
C
A
T
C
C
C
G
C
A
C
G
C
C
A
C
C
T
C
C
T
C
C
G
G
C
C
C
C
C
C
G
C
G
G
C
C
C
C
A
G
C
T
C
G
T
G
G
C
G
C
T
C
G
C
T
C
C
A
G
C
G
G
0.001957
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0.019569
0
0.011742
0.021526
0.02544
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0.027397
0.037182
0.046967
0
0.011742
0.007828
0.007828
0.02544
0.052838
0.050881
0.099804
0.099804
0.029354
0.117417
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0.037182
0.017613
0.02544
0.02544
0.148728
0.029354
0.003914
0
0.005871
0
36,024
G
G
G
C
C
T
C
G
G
C
G
G
A
A
A
C
C
A
A
G
A
G
A
A
G
C
C
A
G
G
C
G
C
T
G
G
A
G
C
G
A
G
C
G
C
C
A
C
G
A
G
C
T
G
G
G
G
C
C
G
C
G
G
G
G
G
0.001957
0.005871
0.015656
0
0.013699
0.019569
0.027397
0.001957
0.023483
0.037182
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0
0.011742
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0.007828
0.029354
0.054795
0.056751
0.107632
0.09589
0.027397
0.111546
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0.039139
0.013699
0.023483
0.023483
0.148728
0.031311
0.003914
0
0.005871
0
36,025
G
T
C
C
T
C
G
G
G
G
C
C
C
G
C
C
T
C
G
G
G
C
T
C
C
A
G
C
G
C
A
T
C
T
T
C
T
G
C
A
G
T
T
C
C
T
G
G
C
A
G
G
G
C
C
G
T
G
T
C
C
A
G
G
T
T
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0.062622
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0.093933
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0.023483
0.076321
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0.04501
0.015656
0.021526
0.031311
0.119374
0.039139
0.009785
0.009785
0.007828
0
36,026
C
A
G
G
C
C
C
C
G
C
A
T
G
T
T
C
C
T
G
C
C
T
C
T
C
T
G
G
C
C
T
G
C
G
T
C
T
C
C
T
C
A
T
T
G
C
C
C
T
T
C
T
C
T
G
T
A
T
C
T
G
T
G
C
A
T
0.033268
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0.041096
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0.031311
0.050881
0.033268
0.037182
0.02544
0.021526
0.037182
0
36,027
G
A
A
G
G
C
A
C
A
C
T
G
A
G
C
A
T
G
G
G
G
C
A
G
C
T
T
T
C
C
C
A
C
C
T
G
G
T
T
C
C
A
G
T
T
G
T
G
G
G
C
A
A
C
A
G
C
A
A
G
A
A
G
T
C
T
0.027397
0.029354
0.048924
0.019569
0.041096
0.029354
0.005871
0.037182
0.054795
0.033268
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0.046967
0.021526
0.048924
0.058708
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0.015656
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0.052838
0.021526
0.037182
0.033268
0.033268
0.013699
0.023483
0.048924
0
36,028
A
T
T
A
T
T
G
T
A
T
T
T
A
A
A
G
A
A
C
T
T
C
C
C
A
C
A
T
T
C
T
G
T
A
C
A
C
T
C
A
T
A
G
G
G
C
C
T
T
T
C
T
C
C
A
A
T
G
T
G
C
A
C
T
T
C
0.04501
0.029354
0.050881
0.031311
0.052838
0.037182
0.013699
0.037182
0.041096
0.019569
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0.019569
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0.02544
0.066536
0.013699
0.031311
0.033268
0.029354
0.033268
0.02544
0.041096
0
36,029
T
G
G
A
A
A
A
G
C
C
T
T
C
C
T
G
A
A
G
A
G
C
T
C
C
A
C
T
C
T
C
C
C
C
A
A
C
C
A
T
C
T
G
A
G
A
A
C
T
C
A
C
T
C
T
G
A
A
G
A
G
A
T
A
C
T
0.04501
0.023483
0.060665
0.029354
0.043053
0.029354
0.001957
0.039139
0.04501
0.037182
0.041096
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0
0.003914
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0.043053
0.060665
0.017613
0.029354
0.017613
0.04501
0.019569
0.023483
0.04501
0
36,030
C
A
A
C
A
G
C
T
T
G
A
A
G
C
T
G
G
A
G
G
A
G
G
T
C
A
C
A
G
C
T
G
C
C
C
A
G
G
A
T
G
A
C
C
T
T
C
C
C
A
C
C
T
T
C
C
C
T
G
C
A
A
G
T
G
T
0.039139
0.023483
0.056751
0.021526
0.04501
0.033268
0.001957
0.031311
0.054795
0.041096
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0
0.003914
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0.058708
0.021526
0.035225
0.019569
0.048924
0.015656
0.013699
0.037182
0
36,031
G
G
A
T
G
T
G
G
A
G
G
C
T
G
G
T
T
C
T
T
G
G
T
G
T
C
C
A
T
G
G
T
T
C
C
C
C
T
C
A
G
G
G
G
A
C
T
G
T
G
C
T
G
C
A
A
G
T
G
G
A
G
G
G
C
G
0.019569
0.005871
0.033268
0.011742
0.039139
0.035225
0.003914
0.027397
0.027397
0.043053
0.068493
0.007828
0.017613
0.033268
0.017613
0.056751
0.074364
0.084149
0.080235
0
0
0
0.013699
0.04501
0.029354
0.035225
0.029354
0.046967
0.07045
0.009785
0.003914
0.029354
0
36,032
C
A
C
A
C
G
G
G
T
A
A
C
T
C
C
G
G
G
G
G
C
C
T
G
T
G
A
G
T
G
A
G
C
G
T
C
G
G
G
G
G
T
G
G
T
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C
G
G
A
A
A
G
G
C
C
A
C
C
T
C
C
C
C
T
T
0.003914
0.007828
0.027397
0
0.041096
0.039139
0.015656
0.039139
0.019569
0.048924
0.035225
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0.035225
0.043053
0.072407
0.039139
0.005871
0.001957
0.023483
0
36,033
T
C
C
C
A
C
A
T
G
T
T
G
C
G
T
G
C
T
A
C
T
T
G
G
G
C
T
G
G
C
C
A
T
G
T
T
A
G
C
A
C
G
G
C
C
C
T
G
G
C
T
C
G
G
C
C
C
C
T
G
G
G
T
G
C
C
0.001957
0.011742
0.023483
0.001957
0.02544
0.023483
0.009785
0.019569
0.017613
0.078278
0.062622
0
0.021526
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0.04501
0.09589
0.078278
0.07045
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0.007828
0.009785
0.060665
0.105675
0.029354
0.011742
0.003914
0.023483
0
36,034
G
C
T
T
G
G
G
C
G
C
A
C
A
G
C
G
G
C
C
C
G
C
T
T
C
T
G
T
G
T
G
G
T
C
T
G
G
A
G
G
T
G
G
A
G
C
T
G
A
G
A
G
G
G
G
A
A
T
C
A
C
A
C
T
C
C
0.009785
0.011742
0.027397
0.013699
0.019569
0.02544
0.027397
0.027397
0.039139
0.02544
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0.046967
0.033268
0.048924
0.084149
0.054795
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0.074364
0.013699
0.060665
0.021526
0.031311
0.02544
0.074364
0.046967
0.009785
0.005871
0.021526
0
36,035
G
G
C
G
A
G
A
C
C
C
A
G
C
A
G
C
C
A
C
C
A
C
C
C
C
C
T
T
C
C
C
C
T
T
T
C
C
C
A
T
C
C
T
A
G
G
A
C
T
C
A
C
C
A
G
G
G
A
G
A
A
G
G
T
G
C
0.011742
0.023483
0.021526
0.011742
0.052838
0.04501
0.007828
0.019569
0.029354
0.046967
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0.027397
0.02544
0.064579
0.072407
0.060665
0.062622
0.015656
0.005871
0.013699
0.015656
0.043053
0.019569
0.019569
0.041096
0.050881
0.037182
0.017613
0.011742
0.033268
0
36,036
G
G
G
C
C
T
C
T
T
G
G
G
G
C
C
C
T
G
T
G
G
C
C
T
C
C
T
C
A
T
A
G
C
G
G
A
A
G
C
A
C
C
G
G
A
A
A
C
G
C
A
G
G
C
G
T
G
C
A
G
C
T
T
C
A
T
0.007828
0.007828
0.019569
0.003914
0.019569
0.031311
0.009785
0.023483
0.033268
0.058708
0.072407
0.009785
0.015656
0.021526
0.009785
0.039139
0.084149
0.048924
0.07045
0.031311
0.007828
0.02544
0.021526
0.062622
0.019569
0.019569
0.052838
0.078278
0.043053
0.015656
0.001957
0.033268
0
36,037
T
T
C
A
T
T
T
A
C
T
C
T
G
C
A
G
A
T
T
T
T
C
C
T
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C
A
A
T
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T
C
C
T
T
G
T
A
C
A
T
A
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T
T
A
T
T
C
C
A
G
C
A
C
T
T
C
T
T
A
A
G
T
T
T
0.060665
0.035225
0.046967
0.048924
0.050881
0.021526
0.007828
0.041096
0.037182
0.017613
0.046967
0.052838
0.017613
0.021526
0.052838
0.031311
0.039139
0.023483
0.017613
0.003914
0.007828
0
0.027397
0.029354
0.04501
0.02544
0.031311
0.021526
0.033268
0.029354
0.035225
0.039139
0
36,038
T
G
G
A
A
G
C
A
T
G
T
A
A
A
A
A
A
A
T
T
A
C
A
A
A
G
C
C
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C
C
T
C
G
T
C
C
A
A
A
G
C
C
A
G
C
A
A
C
A
C
T
T
G
C
A
C
T
G
A
C
T
C
T
T
A
0.07045
0.037182
0.056751
0.050881
0.046967
0.015656
0.007828
0.041096
0.046967
0.019569
0.039139
0.04501
0.019569
0.029354
0.052838
0.027397
0.035225
0.023483
0.009785
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0.009785
0
0.027397
0.027397
0.052838
0.021526
0.037182
0.017613
0.027397
0.02544
0.039139
0.037182
0
36,039
A
C
C
T
T
G
C
A
T
T
T
C
T
T
C
C
T
G
C
A
A
T
A
G
C
C
T
G
T
T
A
C
T
T
T
A
T
T
G
A
A
G
C
A
T
T
T
T
T
T
G
A
G
T
C
T
T
G
C
C
C
C
G
T
C
A
0.060665
0.027397
0.050881
0.04501
0.043053
0.023483
0.003914
0.02544
0.050881
0.029354
0.04501
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0.052838
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0.033268
0.035225
0.023483
0.001957
0.001957
0.003914
0.029354
0.035225
0.048924
0.021526
0.033268
0.023483
0.035225
0.013699
0.039139
0.043053
0
36,040
C
A
C
A
T
A
C
A
C
T
G
C
T
A
C
T
T
C
T
A
C
C
A
A
G
A
G
T
A
A
C
A
C
C
A
A
A
G
A
A
A
G
C
A
G
A
G
A
T
T
C
T
G
C
C
A
C
T
G
C
C
T
C
G
C
G
0.07045
0.033268
0.035225
0.039139
0.043053
0.031311
0.003914
0.039139
0.050881
0.033268
0.023483
0.041096
0.027397
0.041096
0.039139
0.043053
0.043053
0.048924
0.015656
0
0.001957
0.001957
0.035225
0.033268
0.039139
0.015656
0.039139
0.015656
0.02544
0.02544
0.027397
0.037182
0
36,041
T
A
C
A
G
G
C
A
T
G
T
T
C
T
C
C
T
C
A
A
A
C
T
G
G
T
C
A
A
T
A
A
T
C
T
G
A
G
A
G
G
A
A
A
G
G
C
A
C
A
G
C
A
G
G
G
G
A
G
A
A
G
G
G
A
A
0.033268
0.027397
0.039139
0.021526
0.029354
0.037182
0.003914
0.02544
0.043053
0.031311
0.056751
0.017613
0.015656
0.029354
0.033268
0.033268
0.052838
0.058708
0.066536
0.017613
0.007828
0.005871
0.003914
0.060665
0.041096
0.023483
0.029354
0.039139
0.058708
0.011742
0.013699
0.031311
0
36,042
C
C
C
A
T
C
C
C
T
T
A
A
C
C
G
A
G
C
C
T
T
C
C
T
C
T
C
C
T
C
G
C
T
G
C
A
C
C
G
T
C
A
G
T
C
C
C
T
T
T
T
C
C
A
G
G
T
C
T
C
C
A
T
C
C
C
0.015656
0.007828
0.027397
0.001957
0.011742
0.02544
0.013699
0.023483
0.039139
0.041096
0.068493
0
0.019569
0.017613
0.005871
0.02544
0.052838
0.037182
0.117417
0.050881
0.013699
0.031311
0.007828
0.084149
0.02544
0.031311
0.021526
0.058708
0.076321
0.009785
0.005871
0.031311
0
36,043
C
T
G
G
C
C
C
C
T
C
C
G
C
C
T
G
G
C
G
T
T
T
C
A
G
G
G
C
T
G
C
A
C
G
G
A
G
T
A
G
G
T
C
T
G
G
C
G
G
G
C
G
G
G
G
G
G
C
G
G
G
G
C
G
C
G
0.005871
0.009785
0.017613
0.011742
0.013699
0.029354
0.023483
0.015656
0.019569
0.041096
0.072407
0.001957
0.007828
0.009785
0.011742
0.033268
0.050881
0.041096
0.103718
0.064579
0.017613
0.048924
0.011742
0.068493
0.027397
0.033268
0.029354
0.072407
0.076321
0.005871
0
0.023483
0
36,044
A
C
C
T
C
T
T
C
T
A
T
G
A
G
G
A
C
T
G
T
G
C
A
G
G
C
A
C
T
G
C
T
C
T
C
A
G
C
G
A
C
G
A
C
C
C
T
G
A
G
G
G
A
C
C
T
C
C
G
G
T
C
C
T
G
G
0.029354
0.011742
0.031311
0.029354
0.023483
0.035225
0.011742
0.021526
0.029354
0.043053
0.064579
0.013699
0.017613
0.037182
0.02544
0.035225
0.050881
0.035225
0.058708
0.021526
0.011742
0.017613
0.017613
0.058708
0.027397
0.02544
0.050881
0.037182
0.048924
0.019569
0.019569
0.039139
0
36,045
T
A
T
A
C
T
C
A
G
T
G
C
C
T
G
T
A
G
G
G
C
A
G
T
G
C
A
G
G
G
C
C
T
G
G
T
A
G
G
C
C
C
G
C
C
C
G
C
C
C
T
C
C
T
C
G
G
G
C
T
C
C
A
G
G
C
0.009785
0.023483
0.023483
0.005871
0.027397
0.029354
0.015656
0.031311
0.02544
0.037182
0.074364
0.011742
0.015656
0.017613
0.021526
0.031311
0.078278
0.058708
0.086106
0.017613
0.015656
0.013699
0.019569
0.046967
0.021526
0.02544
0.046967
0.066536
0.054795
0.023483
0.009785
0.013699
0
36,046
A
G
G
T
C
A
G
G
G
A
G
G
T
G
C
C
A
G
A
T
C
A
T
G
G
A
G
G
C
C
C
T
C
G
T
G
T
G
C
T
G
C
C
A
C
G
A
G
T
T
G
A
T
T
C
T
A
A
G
A
G
T
A
G
C
T
0.023483
0.039139
0.021526
0.021526
0.068493
0.033268
0.011742
0.031311
0.04501
0.033268
0.043053
0.017613
0.015656
0.039139
0.021526
0.066536
0.060665
0.052838
0.043053
0.003914
0.003914
0.003914
0.02544
0.04501
0.021526
0.015656
0.041096
0.043053
0.023483
0.021526
0.037182
0.02544
0
36,047
A
G
G
G
G
A
C
G
G
C
T
T
C
C
A
G
T
G
C
A
G
C
G
G
G
G
T
G
C
C
G
G
C
C
C
C
C
A
C
C
T
A
C
C
A
C
C
C
C
T
T
G
G
A
G
A
C
A
G
C
C
T
A
C
G
T
0.013699
0.007828
0.023483
0
0.015656
0.027397
0.017613
0.005871
0.019569
0.048924
0.043053
0
0.015656
0.003914
0.015656
0.031311
0.037182
0.041096
0.125245
0.103718
0.021526
0.088063
0.007828
0.050881
0.013699
0.017613
0.02544
0.109589
0.050881
0.009785
0.001957
0.005871
0
36,048
G
A
G
C
G
C
G
T
T
G
A
C
G
A
A
G
G
C
C
A
C
C
A
G
G
G
T
A
T
A
G
A
T
G
A
A
G
G
C
C
A
G
G
T
G
C
G
C
C
G
G
G
C
A
G
C
A
G
G
G
G
G
C
T
G
C
0.007828
0.023483
0.02544
0.013699
0.021526
0.046967
0.019569
0.013699
0.035225
0.027397
0.080235
0.009785
0.015656
0.033268
0.023483
0.039139
0.066536
0.064579
0.052838
0.017613
0.005871
0.019569
0.02544
0.041096
0.037182
0.02544
0.046967
0.066536
0.048924
0.013699
0.001957
0.029354
0
36,049
C
A
A
T
G
A
C
C
A
G
G
T
C
A
C
C
C
T
C
C
A
C
T
C
C
A
T
C
C
G
G
C
C
G
C
G
G
G
A
A
G
A
G
A
A
T
G
A
C
T
T
G
G
G
C
C
C
T
G
C
A
G
G
C
A
T
0.007828
0.015656
0.035225
0.007828
0.017613
0.046967
0.017613
0.011742
0.037182
0.035225
0.078278
0.009785
0.015656
0.02544
0.029354
0.037182
0.060665
0.064579
0.058708
0.027397
0.005871
0.023483
0.015656
0.048924
0.029354
0.031311
0.046967
0.066536
0.058708
0.009785
0
0.023483
0
36,050
C
T
T
G
C
A
T
T
G
G
G
A
A
G
T
G
G
T
G
A
C
A
C
A
C
G
G
T
T
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C
T
T
C
G
G
C
T
T
G
G
G
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G
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C
G
G
T
G
A
C
C
A
G
G
T
A
C
G
C
C
A
C
G
G
0.017613
0.021526
0.027397
0.007828
0.021526
0.043053
0.017613
0.027397
0.033268
0.037182
0.041096
0.003914
0.011742
0.019569
0.023483
0.035225
0.058708
0.050881
0.062622
0.058708
0.019569
0.048924
0.005871
0.046967
0.02544
0.031311
0.04501
0.064579
0.041096
0.021526
0.007828
0.021526
0
36,051
A
C
C
A
G
G
G
A
G
G
C
T
G
C
C
G
A
C
T
G
G
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G
T
G
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G
G
G
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G
G
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G
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G
A
G
G
A
A
T
C
C
G
G
A
G
T
G
G
G
T
C
C
A
C
C
T
C
T
C
T
G
C
0.019569
0.021526
0.031311
0.021526
0.029354
0.033268
0.011742
0.043053
0.029354
0.043053
0.043053
0.011742
0.027397
0.02544
0.023483
0.048924
0.056751
0.054795
0.050881
0.027397
0.007828
0.011742
0.033268
0.035225
0.035225
0.023483
0.039139
0.039139
0.052838
0.023483
0.013699
0.031311
0
36,052
G
T
G
A
A
G
C
A
T
T
T
C
T
T
A
A
A
A
T
G
A
A
G
A
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C
A
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T
T
T
G
C
C
C
A
G
G
T
A
T
A
C
A
T
G
T
A
A
T
A
T
T
G
A
T
T
T
G
T
C
T
C
C
0.099804
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0
0.009785
0
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0.066536
0.009785
0.031311
0.009785
0.027397
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0.056751
0.033268
0
36,053
A
A
T
A
T
T
C
T
C
A
C
C
A
A
A
G
C
T
C
T
C
A
G
C
T
T
G
G
A
A
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A
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T
A
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A
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C
A
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G
T
C
A
A
A
A
T
T
T
T
C
T
C
T
A
A
G
A
G
T
G
A
G
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0.09589
0.027397
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0
0
0
0.043053
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0.054795
0.011742
0.009785
0.007828
0.011742
0.041096
0.043053
0.052838
0
36,054
T
A
A
T
A
T
T
T
T
T
A
T
T
G
G
T
A
T
C
C
T
C
A
T
G
A
G
A
G
C
T
A
T
G
C
T
G
A
G
A
T
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C
A
C
C
A
A
T
C
A
C
A
T
C
C
T
T
C
C
A
A
G
T
T
G
0.097847
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0
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0
0.015656
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0.031311
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0
36,055
T
T
G
T
C
T
C
T
C
T
G
G
T
C
A
A
A
G
G
G
A
G
T
T
C
T
G
C
G
G
C
C
C
G
C
A
A
C
G
G
G
C
T
C
C
T
C
A
C
C
A
A
C
C
A
C
T
A
C
G
T
G
T
G
T
T
0.009785
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0.058708
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0.013699
0.011742
0.041096
0
36,056
G
G
G
C
C
T
G
G
C
T
A
C
T
C
A
C
C
T
G
T
C
C
C
G
A
A
C
C
A
C
C
A
C
G
A
C
A
A
T
C
T
T
A
T
C
G
C
C
T
G
A
T
G
C
C
T
T
C
T
T
C
A
C
C
A
T
0.011742
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0.058708
0.050881
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0.003914
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0
36,057
A
A
T
T
T
G
G
A
T
G
T
T
T
G
T
G
G
T
A
G
G
C
T
C
T
G
A
T
T
C
G
T
C
G
A
T
T
A
A
G
A
T
G
G
A
A
G
A
G
C
T
G
G
C
T
T
T
G
G
C
T
T
C
A
T
T
0.031311
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0.021526
0.052838
0.04501
0.039139
0.019569
0.023483
0.019569
0
36,058
A
T
T
G
T
A
T
A
A
T
A
A
C
T
A
T
T
T
C
G
G
G
A
A
T
G
C
A
G
T
T
A
T
C
T
C
A
T
C
A
T
G
G
T
C
A
G
T
C
T
T
T
G
G
G
G
A
A
G
T
G
G
G
C
T
C
0.066536
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0.058708
0.029354
0.019569
0.023483
0.041096
0.013699
0.037182
0.052838
0
36,059
G
G
T
T
A
G
C
C
C
C
A
G
G
A
G
T
C
T
G
G
G
A
C
T
G
C
T
C
C
C
T
T
C
C
C
A
T
G
A
C
C
A
A
G
C
C
A
T
T
C
A
T
G
G
C
C
C
C
C
T
T
G
C
C
T
A
0.023483
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0
0.003914
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0.04501
0.015656
0.017613
0.039139
0
36,060
G
A
A
C
C
A
C
A
A
G
A
C
A
G
G
T
C
C
A
T
T
T
G
G
T
A
A
G
G
T
A
T
T
G
G
G
T
A
C
G
C
T
G
C
A
A
C
T
C
A
A
G
A
T
G
A
T
T
G
A
C
T
C
C
C
C
0.054795
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0.02544
0.033268
0.029354
0.029354
0.04501
0
36,061
C
C
C
C
A
C
T
C
A
C
C
T
G
C
C
A
G
T
T
C
A
A
G
C
A
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C
A
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A
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A
C
A
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C
A
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T
A
A
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G
A
A
G
G
C
A
G
A
G
G
T
G
G
G
T
G
G
A
G
T
G
G
T
0.035225
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0.054795
0.023483
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0
0.011742
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0.043053
0.027397
0.041096
0.031311
0.046967
0.009785
0.011742
0.039139
0
36,062
T
G
C
C
C
T
C
G
A
C
T
C
A
G
T
G
C
T
C
C
G
A
G
C
A
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A
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A
A
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A
C
A
G
T
T
C
T
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G
C
C
T
C
T
G
T
G
A
T
G
T
C
A
G
A
G
G
A
A
G
G
G
G
T
0.035225
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0.017613
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0.023483
0
0.033268
0.043053
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0.066536
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0
0.015656
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0.04501
0.015656
0.039139
0.039139
0.048924
0.009785
0.011742
0.041096
0
36,063
C
T
C
T
G
C
C
A
T
C
T
A
C
A
T
C
T
G
C
T
G
G
A
A
A
C
A
G
A
A
G
G
C
C
T
G
A
C
T
G
T
A
A
G
T
T
T
A
G
G
A
G
A
G
G
G
A
G
G
A
C
T
G
A
C
T
0.017613
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0.021526
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0.031311
0.054795
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0.076321
0.062622
0.07045
0
0.001957
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0.072407
0.027397
0.019569
0.031311
0.046967
0.068493
0.023483
0.009785
0.039139
0
36,064
C
G
A
A
G
A
G
G
G
T
C
C
C
C
C
T
G
C
A
A
G
G
T
G
A
T
G
T
G
G
G
C
T
A
T
C
T
C
G
C
A
G
A
T
G
A
C
T
T
G
A
G
A
G
T
G
A
A
C
G
T
C
C
C
C
C
0.015656
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0.02544
0.015656
0.037182
0.046967
0.013699
0.023483
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0.04501
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0.062622
0.060665
0.066536
0.068493
0.015656
0.009785
0.007828
0.017613
0.050881
0.023483
0.035225
0.035225
0.04501
0.039139
0.007828
0.009785
0.041096
0
36,065
G
C
C
C
C
A
C
A
G
G
G
A
T
C
A
G
G
G
A
C
G
T
C
A
T
A
G
C
A
C
A
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C
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C
A
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A
G
T
G
G
C
C
G
A
C
T
C
T
C
C
A
G
C
T
G
C
A
A
C
T
G
A
T
T
0.039139
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0.021526
0.041096
0.021526
0.021526
0.041096
0.031311
0.039139
0.046967
0.009785
0.027397
0.027397
0.021526
0.046967
0.068493
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0.029354
0.017613
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0.013699
0.041096
0.039139
0.027397
0.027397
0.039139
0.043053
0.021526
0.02544
0.054795
0
36,066
T
T
T
T
A
A
C
C
G
A
A
G
G
C
A
G
T
G
C
T
C
A
C
C
T
G
T
G
A
G
T
C
T
C
C
C
C
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G
C
A
G
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G
C
G
T
C
A
T
C
A
G
C
A
G
G
A
A
A
G
G
A
C
C
0.037182
0.019569
0.04501
0.031311
0.033268
0.017613
0.009785
0.029354
0.04501
0.054795
0.054795
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0.035225
0.031311
0.080235
0.043053
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0.007828
0.005871
0.015656
0.043053
0.043053
0.027397
0.052838
0.039139
0.048924
0.011742
0.017613
0.037182
0
36,067
C
A
C
C
T
T
G
G
A
G
G
T
T
A
C
T
C
A
A
C
A
G
C
C
C
A
T
G
A
G
G
G
T
G
G
G
G
A
A
C
C
A
G
G
T
A
A
A
C
G
T
C
A
C
C
T
G
C
C
A
G
G
T
G
A
C
0.015656
0.031311
0.029354
0.009785
0.039139
0.058708
0.011742
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0.02544
0.043053
0.033268
0.033268
0.02544
0.015656
0.043053
0
36,068
A
G
C
T
G
G
A
G
A
G
A
C
A
G
C
C
A
C
T
C
T
G
C
G
C
T
G
C
A
C
T
G
C
G
A
C
C
T
C
T
C
T
G
A
T
C
C
C
T
G
T
G
G
G
G
C
C
C
A
T
C
C
A
G
T
T
0.039139
0.033268
0.027397
0.017613
0.043053
0.027397
0.013699
0.037182
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0.035225
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0.033268
0.031311
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0.02544
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0.031311
0.02544
0.04501
0.027397
0.048924
0.015656
0.015656
0.052838
0
36,069
G
G
C
C
T
T
C
T
T
T
T
T
G
A
T
T
G
T
A
G
A
T
T
A
A
T
T
C
C
C
G
G
C
C
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G
G
T
C
C
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G
C
T
C
C
T
C
T
G
A
A
C
C
A
C
T
G
G
A
T
G
G
G
C
G
0.039139
0.029354
0.029354
0.015656
0.046967
0.027397
0.015656
0.037182
0.033268
0.037182
0.043053
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0.02544
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0.052838
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0.031311
0.027397
0.041096
0.033268
0.050881
0.017613
0.015656
0.04501
0
36,070
G
T
T
A
C
C
G
A
T
G
C
G
G
A
T
G
G
A
A
A
A
G
T
C
C
A
T
G
T
T
G
T
T
T
C
T
C
T
T
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G
T
G
A
G
G
T
C
T
G
A
A
A
C
A
G
T
T
G
T
T
A
C
C
C
C
0.039139
0.027397
0.029354
0.023483
0.041096
0.035225
0.007828
0.035225
0.031311
0.037182
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0.029354
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0.029354
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0.04501
0.033268
0.027397
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0.017613
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0.031311
0.023483
0.039139
0.031311
0.050881
0.017613
0.019569
0.04501
0
36,071
G
T
A
A
C
A
A
C
T
G
T
T
T
C
A
G
A
C
C
T
C
A
C
A
A
A
G
A
G
A
A
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C
A
A
C
A
T
G
G
A
C
T
T
T
T
C
C
A
T
C
C
G
C
A
T
C
G
G
T
A
A
C
A
T
A
0.039139
0.027397
0.027397
0.023483
0.043053
0.035225
0.007828
0.035225
0.031311
0.037182
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0.029354
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0.033268
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0.048924
0.031311
0.023483
0.039139
0.031311
0.050881
0.017613
0.017613
0.04501
0
36,072
G
T
A
G
G
T
G
C
C
G
G
C
A
T
C
T
G
C
T
G
G
G
G
T
G
A
T
G
T
T
A
C
C
G
A
T
G
C
G
G
A
T
G
G
A
A
A
A
G
T
C
C
A
T
G
T
T
G
T
T
T
C
T
C
T
T
0.035225
0.027397
0.031311
0.023483
0.043053
0.035225
0.007828
0.033268
0.033268
0.033268
0.046967
0.005871
0.027397
0.02544
0.029354
0.048924
0.060665
0.04501
0.041096
0.027397
0.005871
0.017613
0.007828
0.050881
0.031311
0.023483
0.035225
0.031311
0.052838
0.019569
0.021526
0.041096
0
36,073
C
A
G
C
T
C
A
G
T
G
C
C
T
G
C
T
C
C
A
G
A
C
T
T
A
A
A
C
T
C
C
A
C
G
T
C
A
T
C
G
G
G
G
C
T
C
C
C
T
T
T
C
C
G
G
A
A
C
T
T
C
A
C
A
C
T
0.037182
0.027397
0.033268
0.023483
0.043053
0.033268
0.009785
0.031311
0.037182
0.037182
0.043053
0.007828
0.027397
0.033268
0.027397
0.04501
0.058708
0.04501
0.043053
0.023483
0.005871
0.015656
0.009785
0.04501
0.033268
0.023483
0.035225
0.033268
0.04501
0.021526
0.023483
0.041096
0
36,074
C
A
T
G
C
C
A
A
T
T
C
G
G
T
T
T
G
T
G
C
T
T
C
C
C
A
C
A
A
A
G
A
T
G
A
T
G
C
C
G
G
C
A
T
C
T
T
C
C
T
G
A
A
C
A
T
A
C
T
C
T
T
C
T
C
G
0.029354
0.023483
0.052838
0.027397
0.037182
0.027397
0.005871
0.023483
0.04501
0.041096
0.046967
0.02544
0.033268
0.035225
0.035225
0.027397
0.043053
0.052838
0.050881
0.011742
0.007828
0.005871
0.02544
0.037182
0.043053
0.027397
0.019569
0.027397
0.056751
0.017613
0.02544
0.031311
0
36,075
A
A
T
T
T
T
T
G
A
G
G
A
T
C
T
C
C
A
C
G
C
T
G
C
C
G
T
T
C
C
A
G
C
T
C
C
T
T
G
G
G
T
C
C
C
G
G
C
C
A
C
C
G
G
T
G
T
A
A
G
T
G
C
C
G
T
0.035225
0.015656
0.04501
0.029354
0.023483
0.048924
0.005871
0.029354
0.027397
0.033268
0.043053
0.007828
0.031311
0.029354
0.046967
0.050881
0.046967
0.068493
0.058708
0.019569
0.001957
0.011742
0.015656
0.027397
0.031311
0.029354
0.035225
0.037182
0.043053
0.011742
0.011742
0.046967
0