row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
f_36_ref__4
string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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string
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f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
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G
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G
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A
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C
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A
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T
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C
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C
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A
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C
C
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C
A
A
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C
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C
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0
36,079
A
A
T
A
T
A
A
C
A
G
A
T
G
A
T
G
G
T
C
T
C
A
C
C
T
C
G
C
A
G
G
A
T
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C
A
G
C
T
A
T
G
A
C
T
C
C
T
C
C
A
G
T
C
T
G
G
C
A
G
T
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G
T
C
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0
36,080
C
A
G
C
C
T
G
T
T
C
C
C
C
T
G
T
C
C
T
T
C
C
C
T
T
T
A
G
G
A
G
A
T
G
A
G
T
G
A
A
A
A
A
C
C
C
A
A
A
A
A
G
A
A
G
A
A
A
A
A
G
C
A
A
A
C
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G
G
A
G
C
C
G
G
T
C
A
G
C
A
G
T
G
G
G
C
C
T
G
A
A
G
A
G
G
C
G
G
T
T
G
G
C
A
A
G
A
G
C
A
G
C
T
C
C
A
A
G
A
A
G
A
A
G
A
A
A
A
A
G
T
C
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0.048924
0.011742
0.013699
0.031311
0
36,082
A
T
G
G
C
A
A
G
T
A
G
C
A
T
A
G
C
C
A
C
C
C
A
T
G
T
C
A
G
A
G
G
T
T
C
G
A
A
C
C
T
G
T
G
G
G
G
G
A
G
A
A
T
C
A
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C
A
T
C
A
T
C
C
A
C
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0.043053
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0
36,083
C
T
A
A
G
T
C
A
T
G
T
T
G
C
T
T
C
C
T
G
C
A
G
C
G
C
C
C
A
G
G
A
C
G
G
C
C
T
G
G
C
A
G
G
C
A
G
A
T
C
C
A
A
G
T
C
C
C
C
A
C
T
C
T
C
T
0.009785
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0.019569
0
36,084
C
A
T
T
A
C
A
A
T
T
T
C
A
C
C
A
A
A
T
G
G
A
A
C
G
T
G
G
C
T
T
C
C
A
G
A
T
A
A
C
C
A
G
T
T
C
A
C
G
G
A
T
G
C
C
A
G
A
A
C
A
G
A
A
C
T
0.060665
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0.058708
0.033268
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0
0.001957
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0.07045
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0.017613
0.031311
0.017613
0.043053
0.037182
0
36,085
G
C
G
A
G
G
C
C
T
C
C
T
G
C
T
C
C
T
G
C
T
G
C
T
G
C
T
G
A
C
T
G
C
C
C
A
C
C
T
T
G
G
A
C
C
C
T
C
A
G
A
G
G
C
T
C
A
G
C
A
C
T
G
G
T
T
0.011742
0.003914
0.031311
0.005871
0.013699
0.031311
0
0.019569
0.02544
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0.027397
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0.009785
0.021526
0.086106
0.07045
0.099804
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0.009785
0.058708
0.021526
0.021526
0.041096
0.060665
0.072407
0.017613
0.009785
0.027397
0
36,086
G
G
C
A
G
G
G
A
G
C
G
T
T
G
C
T
T
C
T
C
A
C
C
C
A
G
G
C
A
G
G
G
T
C
G
G
C
A
C
A
G
G
A
G
G
T
G
G
C
C
G
C
A
G
G
G
C
A
G
C
T
G
G
T
A
G
0.021526
0.009785
0.02544
0.009785
0.017613
0.035225
0.013699
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0.09002
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0.007828
0.011742
0.056751
0.02544
0.021526
0.064579
0.060665
0.052838
0.013699
0.003914
0.031311
0
36,087
T
C
C
T
G
A
T
T
T
A
C
C
A
G
A
G
C
A
G
C
C
T
G
G
G
A
G
C
A
T
C
C
T
G
G
G
C
C
C
C
G
A
A
T
G
T
G
C
C
T
C
C
T
G
C
A
A
A
A
G
A
G
T
A
T
C
0.02544
0.011742
0.029354
0.011742
0.011742
0.031311
0.013699
0.019569
0.037182
0.058708
0.068493
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0.019569
0.023483
0.017613
0.029354
0.078278
0.050881
0.060665
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0.007828
0.009785
0.013699
0.064579
0.031311
0.021526
0.056751
0.054795
0.060665
0.013699
0.003914
0.031311
0
36,088
T
C
A
C
A
T
C
A
A
T
T
T
C
A
T
G
A
A
G
C
A
G
A
T
T
G
G
A
G
A
G
A
T
A
G
C
T
C
C
T
C
A
G
C
G
A
A
T
T
C
C
T
T
C
C
C
T
G
G
G
A
G
T
T
C
G
0.04501
0.019569
0.041096
0.072407
0.02544
0.017613
0.009785
0.035225
0.04501
0.02544
0.035225
0.021526
0.039139
0.039139
0.043053
0.031311
0.041096
0.037182
0.011742
0.005871
0.009785
0.009785
0.017613
0.041096
0.054795
0.017613
0.035225
0.019569
0.041096
0.019569
0.035225
0.056751
0
36,089
A
A
G
T
C
T
C
C
T
G
G
C
A
C
C
C
T
G
G
G
A
A
T
C
C
T
G
C
A
T
T
T
T
T
A
A
T
G
G
A
C
G
A
A
C
A
G
G
C
A
G
G
A
A
A
G
A
A
A
A
A
A
A
A
A
G
0.054795
0.021526
0.048924
0.009785
0.035225
0.035225
0.011742
0.029354
0.054795
0.029354
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0.039139
0.04501
0.068493
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0.035225
0.029354
0.029354
0.056751
0.050881
0.031311
0.015656
0.011742
0.021526
0
36,090
A
A
C
A
G
G
T
C
G
T
T
C
A
G
A
T
T
C
T
A
G
G
A
G
A
T
A
A
G
T
T
T
C
C
A
T
G
C
A
C
T
T
T
G
G
T
G
G
C
A
C
A
G
A
A
A
A
T
T
G
A
C
C
G
T
A
0.04501
0.021526
0.050881
0.015656
0.041096
0.027397
0.011742
0.021526
0.064579
0.037182
0.046967
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0.007828
0.007828
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0.043053
0.027397
0.035225
0.037182
0.039139
0.013699
0.019569
0.033268
0
36,091
T
A
T
T
G
T
T
A
A
A
G
T
C
T
T
C
C
T
T
G
T
A
T
T
T
T
C
A
G
G
A
A
C
G
C
T
G
T
C
A
T
A
G
T
A
G
C
C
G
G
C
A
T
C
T
G
G
C
T
T
G
T
C
C
A
T
0.084149
0.027397
0.043053
0.033268
0.056751
0.019569
0.013699
0.029354
0.041096
0.029354
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0.019569
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0.035225
0.029354
0.037182
0.043053
0.035225
0.031311
0.019569
0.001957
0.019569
0.023483
0.02544
0.052838
0.021526
0.015656
0.033268
0.037182
0.033268
0.021526
0.035225
0
36,092
A
G
C
C
T
C
A
A
C
G
C
C
A
G
C
C
T
C
C
A
C
A
C
T
G
C
C
C
T
C
A
A
C
G
C
C
A
G
C
T
T
C
C
T
C
G
C
C
A
G
C
C
C
C
A
C
G
G
A
G
C
T
G
C
C
T
0.009785
0.003914
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0.027397
0.046967
0.078278
0.04501
0.013699
0.001957
0.033268
0
36,093
T
C
A
T
C
T
G
T
G
T
C
A
C
A
C
T
T
G
T
A
G
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A
G
G
G
C
C
T
G
G
C
T
G
T
T
A
A
A
G
T
A
0.019569
0.009785
0.037182
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0.039139
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0.039139
0.039139
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0.048924
0.064579
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0.021526
0.039139
0.039139
0.060665
0.046967
0.009785
0.007828
0.02544
0
36,094
G
G
A
T
G
T
G
C
A
G
A
G
A
G
A
T
C
C
C
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C
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G
G
A
G
A
G
G
C
C
C
G
C
T
C
G
G
G
C
C
C
G
0.015656
0.019569
0.017613
0.017613
0.017613
0.029354
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0.04501
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0.11546
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0.02544
0.033268
0.031311
0.062622
0.058708
0.009785
0.011742
0.015656
0
36,095
A
T
T
C
A
T
G
T
G
A
T
C
C
T
T
G
G
A
A
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A
G
A
A
A
A
C
A
G
A
A
G
G
C
C
A
C
T
A
G
C
0.046967
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0.029354
0.023483
0.011742
0.041096
0.041096
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0.043053
0.021526
0.029354
0.035225
0.043053
0.027397
0.015656
0.048924
0
36,096
C
C
A
T
G
G
A
G
T
T
G
G
G
C
C
C
C
A
C
A
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G
G
T
G
A
G
T
G
A
G
G
C
A
C
C
A
G
G
G
G
G
T
0.009785
0.019569
0.02544
0.007828
0.015656
0.037182
0.007828
0.027397
0.033268
0.041096
0.07045
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0.019569
0.043053
0.074364
0.07045
0.111546
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0.009785
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0.07045
0.02544
0.021526
0.037182
0.056751
0.052838
0.003914
0.007828
0.041096
0
36,097
C
A
G
G
G
A
C
C
A
C
C
C
C
C
T
G
G
G
C
G
G
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C
A
C
A
G
C
C
A
C
T
G
G
A
C
A
G
C
C
C
T
C
0.009785
0.019569
0.02544
0.007828
0.015656
0.035225
0.007828
0.027397
0.029354
0.041096
0.07045
0.009785
0.015656
0.033268
0.021526
0.04501
0.068493
0.074364
0.107632
0.003914
0
0.007828
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0.072407
0.02544
0.017613
0.035225
0.056751
0.058708
0.003914
0.007828
0.043053
0
36,098
C
G
C
T
T
T
G
T
T
C
C
C
A
G
G
A
T
C
C
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T
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G
A
G
C
A
G
C
T
G
C
T
C
C
A
T
C
C
G
A
A
C
0.023483
0.015656
0.033268
0.017613
0.017613
0.033268
0.005871
0.021526
0.037182
0.054795
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0.031311
0.07045
0.060665
0.078278
0.015656
0.017613
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0.013699
0.056751
0.039139
0.021526
0.029354
0.039139
0.064579
0.009785
0.009785
0.031311
0
36,099
G
G
C
C
C
C
A
G
G
C
T
C
A
G
C
C
A
C
C
A
C
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C
C
A
C
G
T
G
T
C
C
T
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T
A
A
G
G
A
C
T
T
0.011742
0.005871
0.017613
0.003914
0.04501
0.037182
0.019569
0.021526
0.009785
0.046967
0.072407
0.009785
0.019569
0.02544
0.017613
0.058708
0.080235
0.078278
0.080235
0.011742
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0.043053
0.005871
0.046967
0.02544
0.064579
0.060665
0.011742
0.003914
0.033268
0
36,100
A
A
C
G
A
T
A
T
G
A
G
G
T
C
C
C
C
T
C
T
G
G
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C
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T
C
A
G
G
A
C
C
A
C
A
G
C
C
T
G
G
C
C
C
G
0.011742
0.009785
0.021526
0.003914
0.041096
0.043053
0.011742
0.019569
0.015656
0.052838
0.072407
0.011742
0.013699
0.02544
0.023483
0.058708
0.072407
0.082192
0.074364
0.009785
0.011742
0.009785
0.013699
0.052838
0.007828
0.037182
0.031311
0.062622
0.058708
0.009785
0.003914
0.02544
0
36,101
G
T
G
A
A
T
C
T
C
G
C
T
C
T
G
A
G
C
C
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T
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G
C
G
C
A
G
G
A
T
C
C
G
G
C
C
G
T
G
G
T
T
0.011742
0.021526
0.027397
0.007828
0.029354
0.037182
0.013699
0.02544
0.033268
0.048924
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0.001957
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0.017613
0.027397
0.048924
0.076321
0.064579
0.048924
0.019569
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0.013699
0.005871
0.068493
0.02544
0.027397
0.046967
0.058708
0.054795
0.007828
0.003914
0.029354
0
36,102
G
T
C
G
T
G
C
G
G
G
A
C
C
A
C
G
A
C
A
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C
T
G
C
A
C
C
G
C
G
T
G
C
T
G
C
A
G
C
A
A
0.011742
0.007828
0.019569
0.001957
0.013699
0.04501
0.031311
0.013699
0.017613
0.048924
0.052838
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0.007828
0.058708
0.048924
0.04501
0.062622
0.07045
0.033268
0.091977
0.021526
0.043053
0.021526
0.027397
0.04501
0.097847
0.02544
0.007828
0
0.017613
0
36,103
T
G
G
A
G
G
C
A
G
C
T
C
A
G
C
C
T
G
G
C
T
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C
C
T
T
G
G
G
T
C
G
G
A
G
C
T
G
A
G
T
A
T
0.009785
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0.02544
0.017613
0.007828
0.039139
0.009785
0.019569
0.035225
0.046967
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0.019569
0.027397
0.02544
0.027397
0.068493
0.082192
0.084149
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0.011742
0.013699
0.019569
0.048924
0.027397
0.019569
0.043053
0.072407
0.052838
0.009785
0.007828
0.015656
0
36,104
A
A
T
T
C
A
A
G
A
C
C
A
G
C
C
T
G
G
G
C
A
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A
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A
A
A
A
A
A
A
T
A
A
A
A
A
T
T
G
A
A
A
A
A
0.080235
0.027397
0.035225
0.039139
0.02544
0.023483
0.017613
0.029354
0.037182
0.039139
0.037182
0.023483
0.021526
0.033268
0.04501
0.029354
0.041096
0.054795
0.02544
0.009785
0.009785
0.005871
0.029354
0.039139
0.02544
0.021526
0.035225
0.048924
0.027397
0.017613
0.031311
0.033268
0
36,105
T
A
T
G
A
T
G
G
G
C
C
T
G
C
T
C
A
T
G
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C
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C
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C
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T
G
C
C
C
C
A
G
C
0.013699
0.029354
0.023483
0.005871
0.033268
0.060665
0.017613
0.027397
0.009785
0.050881
0.027397
0.009785
0.015656
0.054795
0.033268
0.068493
0.054795
0.09002
0.064579
0.019569
0.011742
0.013699
0.009785
0.027397
0.015656
0.019569
0.046967
0.056751
0.017613
0.021526
0.009785
0.039139
0
36,106
G
C
T
C
C
T
C
T
G
C
C
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T
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C
C
A
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C
T
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G
C
A
G
T
A
T
0.015656
0.017613
0.02544
0.017613
0.019569
0.031311
0.017613
0.027397
0.041096
0.062622
0.039139
0.007828
0.017613
0.02544
0.031311
0.046967
0.072407
0.060665
0.039139
0.019569
0.011742
0.033268
0.017613
0.056751
0.023483
0.019569
0.066536
0.052838
0.035225
0.011742
0.005871
0.029354
0
36,107
T
G
C
T
G
A
G
A
G
T
G
G
A
A
A
G
A
G
T
G
C
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G
A
G
C
A
G
A
A
A
T
T
C
C
C
G
G
A
A
A
A
T
0.097847
0.023483
0.041096
0.07045
0.064579
0.015656
0.005871
0.029354
0.041096
0.019569
0.019569
0.07045
0.029354
0.043053
0.029354
0.048924
0.027397
0.019569
0.011742
0.005871
0
0
0.013699
0.027397
0.041096
0.013699
0.017613
0.005871
0.023483
0.029354
0.066536
0.046967
0
36,108
A
G
A
G
G
A
G
A
G
C
A
G
T
G
C
T
T
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G
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A
G
A
T
T
A
C
G
T
C
C
T
G
C
A
G
G
G
A
C
T
0.082192
0.029354
0.050881
0.039139
0.035225
0.017613
0.009785
0.02544
0.056751
0.043053
0.041096
0.023483
0.027397
0.023483
0.041096
0.023483
0.056751
0.041096
0.013699
0.001957
0.001957
0.005871
0.021526
0.037182
0.043053
0.021526
0.037182
0.029354
0.037182
0.013699
0.035225
0.033268
0
36,109
A
A
G
T
A
A
G
A
T
T
G
T
T
A
A
G
A
G
A
C
C
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C
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A
G
T
C
C
T
C
C
A
G
C
A
G
G
G
G
A
G
A
G
A
0.052838
0.015656
0.048924
0.041096
0.031311
0.009785
0.007828
0.029354
0.060665
0.039139
0.050881
0.023483
0.023483
0.02544
0.035225
0.023483
0.043053
0.031311
0.035225
0.009785
0.009785
0.009785
0.013699
0.072407
0.04501
0.023483
0.019569
0.033268
0.048924
0.015656
0.02544
0.04501
0
36,110
C
C
G
C
C
T
C
C
C
T
C
T
G
C
C
C
A
T
T
T
C
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G
G
A
T
G
T
C
C
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C
C
T
C
C
C
C
T
G
G
G
0.048924
0.017613
0.048924
0.02544
0.037182
0.011742
0.009785
0.02544
0.072407
0.037182
0.054795
0.013699
0.021526
0.021526
0.035225
0.029354
0.04501
0.031311
0.039139
0.009785
0.011742
0.011742
0.013699
0.082192
0.048924
0.02544
0.017613
0.035225
0.048924
0.011742
0.011742
0.04501
0
36,111
C
A
A
G
G
T
G
T
T
T
C
T
C
T
T
C
A
C
T
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C
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G
A
T
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G
T
T
C
T
C
T
C
C
C
T
C
C
T
C
C
T
0.037182
0.013699
0.04501
0.011742
0.029354
0.005871
0.005871
0.021526
0.082192
0.04501
0.064579
0.011742
0.019569
0.019569
0.017613
0.027397
0.048924
0.039139
0.050881
0.019569
0.017613
0.011742
0.015656
0.101761
0.046967
0.019569
0.019569
0.052838
0.064579
0.001957
0.005871
0.02544
0
36,112
T
T
T
T
T
T
T
A
T
A
G
C
T
G
A
A
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T
T
G
A
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G
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T
T
T
G
T
G
T
C
T
C
T
C
C
T
G
G
C
T
C
T
T
G
0.039139
0.015656
0.04501
0.011742
0.031311
0.015656
0.009785
0.019569
0.086106
0.039139
0.060665
0.011742
0.019569
0.019569
0.017613
0.037182
0.046967
0.041096
0.039139
0.017613
0.017613
0.013699
0.015656
0.097847
0.048924
0.021526
0.019569
0.048924
0.052838
0.001957
0.005871
0.031311
0
36,113
A
G
A
C
T
C
C
T
G
G
G
G
G
T
G
A
T
T
C
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C
T
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C
T
G
G
C
T
A
C
T
C
T
T
C
T
C
T
C
C
0.046967
0.017613
0.043053
0.009785
0.023483
0.023483
0.013699
0.019569
0.074364
0.031311
0.078278
0.009785
0.017613
0.017613
0.015656
0.033268
0.04501
0.039139
0.046967
0.013699
0.013699
0.005871
0.015656
0.099804
0.046967
0.027397
0.017613
0.039139
0.068493
0.001957
0.007828
0.035225
0
36,114
A
G
A
A
G
A
A
A
T
A
A
A
G
G
G
T
T
A
T
C
C
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G
G
A
G
T
G
G
G
A
G
C
G
C
T
A
T
A
G
G
G
G
0.027397
0.015656
0.043053
0.011742
0.021526
0.031311
0.019569
0.019569
0.058708
0.023483
0.080235
0.021526
0.015656
0.02544
0.017613
0.037182
0.046967
0.048924
0.062622
0.007828
0.005871
0.009785
0.013699
0.078278
0.04501
0.033268
0.015656
0.041096
0.064579
0.005871
0.009785
0.041096
0
36,115
T
G
A
A
G
A
A
A
G
T
G
A
G
G
A
A
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C
C
A
T
C
A
C
A
G
A
G
G
C
A
G
G
G
G
A
G
T
0.029354
0.017613
0.054795
0.013699
0.027397
0.031311
0.013699
0.019569
0.058708
0.029354
0.074364
0.023483
0.017613
0.023483
0.023483
0.041096
0.048924
0.048924
0.050881
0.007828
0
0.009785
0.015656
0.062622
0.052838
0.02544
0.023483
0.035225
0.064579
0.007828
0.011742
0.035225
0
36,116
C
A
C
G
T
G
G
C
T
C
C
C
C
T
C
C
C
C
T
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C
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C
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G
C
T
C
A
A
G
G
C
C
C
C
T
C
T
C
T
T
C
C
T
0.031311
0.017613
0.056751
0.011742
0.027397
0.031311
0.013699
0.017613
0.058708
0.033268
0.076321
0.023483
0.017613
0.021526
0.023483
0.039139
0.048924
0.046967
0.048924
0.007828
0
0.009785
0.017613
0.062622
0.052838
0.02544
0.023483
0.035225
0.064579
0.007828
0.011742
0.035225
0
36,117
G
G
G
C
C
T
C
T
G
C
C
A
T
G
C
T
G
T
C
T
T
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T
T
T
C
C
T
C
C
A
G
T
G
T
G
C
C
A
T
T
A
C
0.07045
0.04501
0.050881
0.031311
0.043053
0.021526
0
0.027397
0.072407
0.027397
0.029354
0.023483
0.029354
0.041096
0.043053
0.017613
0.050881
0.052838
0.031311
0.001957
0.001957
0
0.011742
0.043053
0.052838
0.019569
0.021526
0.02544
0.037182
0.009785
0.033268
0.033268
0
36,118
C
C
C
C
A
C
A
G
T
T
T
T
T
G
C
T
T
T
C
A
A
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C
A
A
C
A
T
T
G
G
A
T
C
G
A
T
T
C
A
T
A
A
0.11546
0.037182
0.046967
0.058708
0.039139
0.021526
0.003914
0.041096
0.041096
0.023483
0.017613
0.054795
0.027397
0.046967
0.043053
0.011742
0.027397
0.023483
0.017613
0.001957
0.003914
0.001957
0.029354
0.017613
0.043053
0.019569
0.021526
0.003914
0.017613
0.037182
0.058708
0.04501
0
36,119
G
A
A
A
T
A
T
A
T
T
A
T
T
A
T
A
A
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T
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A
A
A
T
A
A
A
T
C
T
T
T
T
C
G
C
T
G
T
T
C
0.091977
0.052838
0.04501
0.060665
0.043053
0.017613
0.003914
0.033268
0.050881
0.029354
0.029354
0.041096
0.019569
0.035225
0.046967
0.007828
0.043053
0.019569
0.013699
0.001957
0.005871
0.003914
0.031311
0.023483
0.062622
0.013699
0.02544
0.011742
0.019569
0.023483
0.048924
0.043053
0
36,120
G
G
C
G
C
G
T
C
G
C
T
T
A
C
T
C
G
G
C
C
G
C
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G
C
G
C
A
G
G
G
C
C
C
C
C
C
A
C
G
A
G
C
T
0.001957
0.009785
0.029354
0
0.013699
0.017613
0.021526
0.019569
0.011742
0.068493
0.033268
0.005871
0.003914
0.009785
0.013699
0.029354
0.060665
0.054795
0.074364
0.086106
0.02544
0.105675
0.007828
0.035225
0.017613
0.015656
0.041096
0.125245
0.031311
0.019569
0.005871
0.003914
0
36,121
C
A
G
G
G
C
G
C
G
G
A
G
G
C
T
G
C
T
C
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G
C
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C
C
A
G
C
T
G
G
T
T
G
T
A
G
C
C
0
0.019569
0.011742
0.001957
0.009785
0.037182
0.017613
0.007828
0.007828
0.07045
0.050881
0
0.011742
0.005871
0.013699
0.031311
0.078278
0.037182
0.068493
0.072407
0.029354
0.123288
0.003914
0.043053
0.017613
0.017613
0.064579
0.09002
0.033268
0.003914
0
0.019569
0
36,122
T
G
C
T
G
T
C
A
T
T
T
T
C
T
A
G
T
T
G
G
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A
A
C
A
A
G
G
C
A
T
C
C
A
A
G
A
G
G
A
T
T
0.093933
0.015656
0.043053
0.066536
0.033268
0.009785
0.003914
0.027397
0.041096
0.031311
0.035225
0.080235
0.033268
0.046967
0.035225
0.015656
0.037182
0.017613
0.009785
0
0.007828
0.003914
0.019569
0.035225
0.043053
0.021526
0.029354
0.013699
0.029354
0.019569
0.04501
0.054795
0
36,123
G
A
A
G
A
A
A
A
A
A
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A
C
A
A
A
A
A
T
A
A
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T
C
T
A
A
A
C
C
T
G
G
A
G
A
G
T
T
C
T
C
C
0.129159
0.04501
0.060665
0.052838
0.033268
0.017613
0.005871
0.031311
0.07045
0.013699
0.031311
0.035225
0.023483
0.029354
0.031311
0.013699
0.033268
0.015656
0.023483
0.001957
0
0
0.021526
0.031311
0.07045
0.017613
0.013699
0.003914
0.027397
0.013699
0.056751
0.04501
0
36,124
G
C
A
T
T
C
T
G
A
T
T
C
A
C
C
A
A
C
C
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G
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A
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C
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G
C
T
G
T
T
G
C
A
0.07045
0.041096
0.043053
0.035225
0.033268
0.037182
0.009785
0.02544
0.046967
0.023483
0.031311
0.019569
0.035225
0.035225
0.037182
0.041096
0.039139
0.052838
0.027397
0.015656
0.011742
0.005871
0.017613
0.027397
0.054795
0.019569
0.035225
0.017613
0.04501
0.003914
0.029354
0.031311
0
36,125
C
T
C
T
A
C
T
T
C
C
T
C
C
C
G
G
G
T
C
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A
T
C
A
T
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G
G
C
C
T
C
A
C
T
T
C
T
C
T
T
0.046967
0.015656
0.060665
0.02544
0.031311
0.015656
0.005871
0.015656
0.066536
0.041096
0.064579
0.013699
0.039139
0.035225
0.035225
0.019569
0.050881
0.02544
0.023483
0.009785
0.003914
0.007828
0.009785
0.066536
0.054795
0.019569
0.031311
0.029354
0.054795
0.013699
0.013699
0.052838
0
36,126
A
T
T
G
G
A
A
G
A
G
A
A
A
G
G
A
C
A
T
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C
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T
A
C
G
T
A
G
C
A
C
A
G
G
C
T
A
A
G
C
A
T
0.054795
0.017613
0.048924
0.041096
0.039139
0.023483
0.021526
0.021526
0.031311
0.027397
0.037182
0.043053
0.017613
0.031311
0.031311
0.033268
0.035225
0.02544
0.037182
0.029354
0.013699
0.041096
0.011742
0.021526
0.039139
0.02544
0.041096
0.033268
0.033268
0.029354
0.037182
0.02544
0
36,127
G
A
G
C
T
G
A
G
G
T
G
A
A
G
G
G
C
C
G
C
T
G
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C
C
A
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C
C
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C
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A
A
G
T
G
T
T
C
T
G
G
G
T
G
G
A
T
C
G
C
G
0.021526
0.027397
0.031311
0.005871
0.031311
0.023483
0.017613
0.019569
0.02544
0.050881
0.039139
0.009785
0.019569
0.019569
0.029354
0.033268
0.048924
0.035225
0.086106
0.048924
0.019569
0.074364
0.011742
0.041096
0.023483
0.021526
0.043053
0.058708
0.039139
0.009785
0.011742
0.021526
0
36,128
C
C
A
C
C
C
A
G
A
G
C
T
C
A
T
C
G
C
C
G
A
C
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G
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C
C
A
C
A
T
T
G
T
C
A
T
G
G
T
G
G
T
A
A
T
0.052838
0.017613
0.046967
0.048924
0.041096
0.031311
0.003914
0.035225
0.04501
0.027397
0.035225
0.033268
0.023483
0.043053
0.043053
0.031311
0.033268
0.035225
0.031311
0.007828
0.009785
0.005871
0.029354
0.033268
0.046967
0.02544
0.027397
0.021526
0.02544
0.035225
0.023483
0.048924
0
36,129
A
G
C
C
A
G
G
C
C
A
G
G
A
G
C
C
A
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A
C
T
G
C
A
C
G
A
T
T
G
G
T
C
C
G
T
A
G
A
0.07045
0.02544
0.050881
0.048924
0.021526
0.019569
0.017613
0.017613
0.035225
0.043053
0.041096
0.023483
0.031311
0.039139
0.031311
0.027397
0.035225
0.039139
0.023483
0.015656
0.013699
0.011742
0.023483
0.027397
0.04501
0.017613
0.035225
0.039139
0.037182
0.005871
0.048924
0.037182
0
36,130
C
G
A
A
G
T
C
C
A
C
C
T
C
A
T
G
T
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T
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A
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T
C
C
T
G
A
T
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A
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C
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C
T
G
C
T
G
T
T
T
0.091977
0.035225
0.054795
0.043053
0.033268
0.019569
0.005871
0.041096
0.04501
0.037182
0.023483
0.046967
0.02544
0.033268
0.037182
0.023483
0.035225
0.035225
0.023483
0.001957
0.013699
0.001957
0.023483
0.031311
0.041096
0.017613
0.02544
0.017613
0.023483
0.023483
0.054795
0.033268
0
36,131
T
C
A
A
A
C
A
G
T
C
C
A
A
G
G
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C
A
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G
T
G
G
A
A
G
G
C
A
G
C
T
T
T
G
T
G
G
C
A
0.064579
0.035225
0.041096
0.048924
0.062622
0.013699
0.007828
0.031311
0.048924
0.041096
0.023483
0.035225
0.019569
0.033268
0.054795
0.037182
0.050881
0.04501
0.009785
0
0.003914
0
0.027397
0.02544
0.04501
0.02544
0.029354
0.033268
0.021526
0.017613
0.02544
0.041096
0
36,132
A
A
G
A
A
C
T
C
A
A
C
T
G
G
T
C
T
T
T
C
T
T
A
A
G
A
A
G
C
A
C
A
C
G
T
C
G
T
C
C
A
T
T
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G
T
G
C
C
A
C
A
A
A
G
C
T
G
C
C
T
T
C
C
A
T
0.060665
0.037182
0.04501
0.052838
0.058708
0.013699
0.007828
0.033268
0.050881
0.041096
0.021526
0.023483
0.021526
0.035225
0.058708
0.037182
0.050881
0.043053
0.007828
0
0.003914
0
0.023483
0.027397
0.050881
0.021526
0.031311
0.031311
0.019569
0.017613
0.02544
0.046967
0
36,133
A
G
A
A
A
T
A
T
G
A
C
A
T
G
A
G
T
A
A
A
A
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T
C
C
A
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C
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A
G
T
G
G
C
C
T
A
A
G
T
G
A
A
A
G
A
G
A
C
G
0.078278
0.029354
0.039139
0.064579
0.035225
0.013699
0.007828
0.046967
0.039139
0.029354
0.019569
0.054795
0.021526
0.046967
0.039139
0.023483
0.037182
0.029354
0.007828
0.001957
0.005871
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0.023483
0.035225
0.046967
0.015656
0.029354
0.015656
0.021526
0.035225
0.046967
0.054795
0
36,134
T
C
T
G
G
T
C
T
G
C
G
A
T
T
T
G
C
T
C
G
T
G
A
C
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C
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T
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T
T
T
C
A
C
A
C
T
G
A
A
A
C
A
A
A
C
A
A
C
0.076321
0.02544
0.035225
0.033268
0.043053
0.023483
0.001957
0.035225
0.035225
0.037182
0.041096
0.019569
0.033268
0.035225
0.031311
0.041096
0.066536
0.048924
0.033268
0
0.005871
0.003914
0.015656
0.031311
0.04501
0.021526
0.037182
0.019569
0.046967
0.013699
0.017613
0.04501
0
36,135
T
T
T
T
T
T
C
C
A
C
T
A
T
T
A
T
T
T
C
T
C
T
C
G
G
G
A
C
T
A
A
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C
G
A
T
C
A
C
T
T
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C
A
A
G
A
G
A
A
A
C
T
C
T
C
C
C
G
T
G
G
T
G
G
T
0.084149
0.043053
0.050881
0.017613
0.035225
0.02544
0.011742
0.035225
0.054795
0.04501
0.023483
0.009785
0.023483
0.015656
0.041096
0.029354
0.060665
0.052838
0.033268
0.013699
0.011742
0.005871
0.017613
0.031311
0.04501
0.029354
0.029354
0.029354
0.035225
0.005871
0.02544
0.027397
0
36,136
G
A
G
A
C
C
T
T
G
C
A
T
C
A
C
C
A
T
G
G
G
G
A
G
T
G
T
G
A
T
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C
C
A
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A
T
G
G
G
G
C
C
A
A
A
T
G
G
G
A
T
G
A
T
G
A
C
T
G
T
A
A
T
A
G
0.029354
0.023483
0.031311
0.021526
0.04501
0.031311
0.005871
0.021526
0.031311
0.039139
0.043053
0.009785
0.035225
0.054795
0.027397
0.041096
0.074364
0.058708
0.039139
0.013699
0.013699
0.011742
0.003914
0.027397
0.031311
0.023483
0.056751
0.048924
0.035225
0.015656
0.017613
0.037182
0
36,137
C
C
A
T
C
T
G
C
A
G
T
G
C
C
C
C
A
G
G
G
C
C
T
C
T
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T
T
T
G
A
T
T
T
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A
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A
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T
A
T
C
A
G
A
C
G
A
C
T
A
T
A
A
C
T
G
G
G
0.082192
0.031311
0.050881
0.037182
0.037182
0.027397
0.005871
0.02544
0.050881
0.023483
0.048924
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0.027397
0.048924
0.023483
0.046967
0.041096
0.021526
0.003914
0.003914
0.001957
0.021526
0.029354
0.043053
0.015656
0.033268
0.031311
0.033268
0.02544
0.027397
0.035225
0
36,138
A
T
C
T
C
A
A
C
A
T
G
T
T
G
T
T
A
G
T
T
T
G
A
T
T
T
C
C
T
T
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G
C
G
T
T
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C
A
T
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A
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G
T
T
G
A
G
C
A
T
T
T
T
T
C
A
T
G
T
G
T
T
T
T
0.088063
0.037182
0.02544
0.058708
0.054795
0.02544
0.001957
0.029354
0.023483
0.017613
0.021526
0.107632
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0.072407
0.043053
0.023483
0.015656
0.031311
0.009785
0
0.007828
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0.023483
0.02544
0.039139
0.005871
0.013699
0.017613
0.011742
0.04501
0.039139
0.054795
0
36,139
A
G
A
T
T
T
A
A
T
C
A
A
C
A
T
T
G
A
C
A
A
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C
A
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G
A
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C
A
A
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G
A
C
T
T
C
C
T
T
T
G
T
G
A
T
T
C
C
T
T
T
T
C
A
A
T
C
T
C
A
C
G
0.154599
0.035225
0.052838
0.082192
0.039139
0.007828
0.005871
0.02544
0.039139
0.015656
0.02544
0.035225
0.031311
0.027397
0.062622
0.011742
0.019569
0.023483
0.013699
0.007828
0.001957
0
0.011742
0.021526
0.052838
0.011742
0.021526
0.009785
0.039139
0.021526
0.054795
0.037182
0
36,140
C
T
T
A
G
C
T
T
C
C
T
C
T
A
G
T
G
A
A
G
A
T
G
A
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A
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A
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A
T
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A
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A
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C
T
A
C
A
A
G
G
T
A
T
T
G
T
T
A
A
T
C
T
T
T
C
0.105675
0.033268
0.056751
0.054795
0.04501
0.019569
0.001957
0.031311
0.043053
0.029354
0.033268
0.052838
0.02544
0.043053
0.037182
0.021526
0.029354
0.027397
0.005871
0
0.001957
0
0.031311
0.019569
0.043053
0.021526
0.021526
0.011742
0.027397
0.021526
0.066536
0.037182
0
36,141
C
C
T
G
G
G
C
T
G
A
T
T
T
T
G
T
T
G
C
T
T
A
G
A
A
A
T
C
A
C
C
A
T
G
G
G
T
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G
G
A
T
G
C
G
G
A
T
C
A
C
A
G
G
A
A
A
A
C
C
T
G
C
T
C
G
0.043053
0.041096
0.04501
0.027397
0.037182
0.041096
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0.035225
0.04501
0.027397
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0.037182
0.027397
0.052838
0.041096
0.046967
0.07045
0.043053
0.009785
0.001957
0.007828
0.015656
0.033268
0.046967
0.027397
0.021526
0.013699
0.058708
0.007828
0.013699
0.037182
0
36,142
G
A
G
A
A
A
A
T
C
T
C
C
T
G
G
A
G
A
A
A
A
A
G
A
A
G
A
A
T
C
A
A
C
G
T
A
A
A
A
T
A
A
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A
A
T
A
A
A
A
G
G
A
A
T
T
C
A
A
A
A
T
A
A
A
T
0.146771
0.021526
0.048924
0.093933
0.046967
0.005871
0.005871
0.02544
0.058708
0.013699
0.013699
0.066536
0.027397
0.039139
0.048924
0.019569
0.017613
0.005871
0.001957
0
0.001957
0
0.021526
0.023483
0.058708
0.015656
0.019569
0.001957
0.011742
0.027397
0.056751
0.052838
0
36,143
T
A
T
A
T
A
T
C
C
A
T
T
T
T
C
T
A
T
T
A
C
A
G
A
A
G
A
A
A
A
T
A
C
T
C
A
G
G
A
A
A
C
A
T
C
C
C
A
G
G
T
G
A
A
G
A
A
A
A
G
T
T
T
G
A
T
0.117417
0.031311
0.037182
0.076321
0.058708
0.015656
0.005871
0.035225
0.056751
0.011742
0.011742
0.074364
0.02544
0.039139
0.046967
0.02544
0.011742
0.015656
0.007828
0.003914
0.003914
0.001957
0.039139
0.027397
0.037182
0.019569
0.011742
0.001957
0.013699
0.039139
0.058708
0.037182
0
36,144
G
G
C
T
C
C
A
G
G
G
C
T
G
T
G
A
C
C
A
A
G
T
A
C
T
C
A
C
T
G
C
G
T
T
C
C
C
C
T
G
T
T
A
C
A
A
T
T
G
T
T
T
C
T
G
T
T
A
T
A
G
A
T
C
C
G
0.043053
0.041096
0.037182
0.035225
0.037182
0.04501
0.001957
0.033268
0.035225
0.033268
0.041096
0.027397
0.023483
0.029354
0.054795
0.027397
0.052838
0.058708
0.043053
0.003914
0.007828
0.001957
0.017613
0.035225
0.033268
0.017613
0.02544
0.033268
0.02544
0.031311
0.02544
0.041096
0
36,145
A
C
T
G
T
T
T
T
G
A
A
C
A
G
G
A
C
A
A
G
A
G
A
A
T
G
A
T
T
C
A
A
C
G
A
A
G
A
A
T
G
A
A
A
T
A
A
A
A
A
T
T
G
A
A
A
C
A
G
A
A
T
C
G
C
T
0.109589
0.037182
0.031311
0.064579
0.043053
0.021526
0.007828
0.02544
0.048924
0.011742
0.023483
0.07045
0.039139
0.041096
0.041096
0.033268
0.033268
0.019569
0.007828
0.003914
0.003914
0.003914
0.023483
0.021526
0.064579
0.009785
0.02544
0.005871
0.019569
0.017613
0.027397
0.062622
0
36,146
T
G
G
T
T
C
A
A
A
A
T
G
G
C
C
A
G
C
A
T
G
C
T
C
A
G
G
A
T
G
A
C
C
A
T
A
T
T
T
G
T
T
T
T
C
A
C
T
G
T
C
C
T
G
G
A
A
T
A
C
C
T
C
G
G
A
0.058708
0.027397
0.043053
0.021526
0.02544
0.027397
0.009785
0.037182
0.050881
0.033268
0.041096
0.019569
0.035225
0.041096
0.037182
0.02544
0.060665
0.043053
0.019569
0.007828
0.007828
0.005871
0.009785
0.048924
0.033268
0.031311
0.041096
0.029354
0.035225
0.013699
0.023483
0.054795
0
36,147
G
G
C
G
T
C
T
T
T
G
G
A
C
T
T
C
T
T
C
T
T
C
A
A
T
G
T
A
A
G
C
A
T
T
G
A
T
C
C
T
G
T
A
A
C
A
C
A
A
T
G
G
A
G
A
T
G
G
A
G
T
A
G
A
T
C
0.076321
0.043053
0.054795
0.031311
0.046967
0.021526
0.011742
0.043053
0.056751
0.019569
0.035225
0.011742
0.033268
0.029354
0.048924
0.035225
0.039139
0.033268
0.011742
0
0.007828
0.003914
0.023483
0.035225
0.054795
0.017613
0.029354
0.013699
0.033268
0.027397
0.027397
0.043053
0
36,148
T
T
C
T
G
C
G
C
T
G
C
A
G
A
G
G
C
A
C
T
C
C
A
C
C
C
T
G
G
G
C
A
T
G
G
A
G
A
T
T
G
A
A
G
A
G
C
A
G
A
G
G
C
A
G
A
A
A
C
T
T
G
C
C
A
C
0.080235
0.015656
0.048924
0.029354
0.021526
0.015656
0.003914
0.027397
0.052838
0.046967
0.058708
0.015656
0.009785
0.027397
0.031311
0.031311
0.066536
0.050881
0.017613
0.001957
0
0.009785
0.009785
0.062622
0.046967
0.011742
0.054795
0.046967
0.048924
0.009785
0.015656
0.029354
0
36,149
A
A
T
A
T
T
T
A
T
G
G
A
C
C
G
T
C
T
A
G
C
T
T
C
C
A
A
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A
G
C
T
C
T
G
T
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C
A
G
A
T
G
A
T
G
A
G
T
G
T
G
T
C
T
G
T
A
A
G
G
A
C
T
C
0.066536
0.023483
0.060665
0.041096
0.041096
0.019569
0.005871
0.029354
0.054795
0.04501
0.021526
0.052838
0.021526
0.033268
0.031311
0.027397
0.046967
0.039139
0.021526
0.013699
0.005871
0.001957
0.019569
0.023483
0.054795
0.021526
0.027397
0.02544
0.029354
0.023483
0.039139
0.031311
0
36,150
A
G
T
C
C
A
G
T
G
T
T
G
G
G
G
A
G
C
G
T
T
A
C
C
T
T
T
C
C
C
A
C
C
G
G
A
T
C
C
A
G
T
G
C
T
G
A
G
A
G
A
G
A
C
T
C
C
A
T
G
G
C
T
C
T
T
0.078278
0.027397
0.048924
0.031311
0.033268
0.019569
0.005871
0.02544
0.056751
0.043053
0.041096
0.015656
0.019569
0.043053
0.027397
0.021526
0.046967
0.041096
0.033268
0.005871
0.009785
0.005871
0.019569
0.052838
0.046967
0.02544
0.02544
0.027397
0.039139
0.009785
0.033268
0.039139
0
36,151
C
T
G
T
G
C
A
T
C
T
G
T
C
C
A
G
G
T
G
A
G
G
G
A
G
C
A
C
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C
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C
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G
A
G
G
C
A
G
A
G
C
T
G
G
A
A
A
A
G
C
A
C
A
T
G
G
T
0.021526
0.011742
0.031311
0.003914
0.023483
0.023483
0.017613
0.02544
0.033268
0.054795
0.068493
0.003914
0.013699
0.017613
0.023483
0.04501
0.074364
0.039139
0.058708
0.02544
0.015656
0.027397
0.011742
0.066536
0.015656
0.023483
0.066536
0.07045
0.039139
0.007828
0.007828
0.031311
0
36,152
G
G
A
G
A
G
G
A
A
G
G
C
T
C
T
C
A
G
C
C
T
G
G
G
A
G
A
C
A
T
G
T
T
G
T
C
C
A
T
C
T
C
C
T
G
C
G
A
C
A
G
C
A
G
T
G
G
G
G
A
G
A
G
A
G
C
0.023483
0.011742
0.037182
0.029354
0.031311
0.02544
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0.027397
0.046967
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0.060665
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0.043053
0.027397
0.039139
0.043053
0.058708
0.013699
0.011742
0.033268
0
36,153
C
T
G
G
A
G
A
C
C
C
C
G
G
A
A
T
G
T
T
C
T
T
T
T
T
A
A
A
A
C
T
T
T
C
C
T
C
G
G
C
T
T
C
G
T
G
G
T
G
A
C
C
A
G
T
A
G
G
T
G
A
A
C
G
T
G
0.054795
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0.041096
0.027397
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0.033268
0.035225
0.043053
0.013699
0.021526
0.02544
0
36,154
G
C
T
G
C
T
C
G
C
C
G
C
C
A
T
C
C
C
C
A
G
C
G
C
G
G
G
A
A
G
C
A
C
C
C
G
T
G
A
G
A
C
C
C
G
G
G
C
G
G
C
C
C
C
T
C
T
C
C
C
T
G
G
T
C
T
0.019569
0.017613
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0.013699
0.013699
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0.064579
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0.035225
0.037182
0.035225
0.07045
0.052838
0.001957
0.011742
0.021526
0
36,155
A
A
G
G
G
C
A
G
C
T
G
A
T
T
C
C
A
C
A
G
A
A
A
A
C
T
T
T
G
A
A
C
T
C
C
T
G
A
G
C
T
G
C
C
T
G
C
A
A
A
T
G
G
T
C
T
G
A
A
A
T
A
A
C
T
A
0.09002
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0.054795
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0.052838
0.033268
0.033268
0.02544
0.029354
0.007828
0.023483
0.039139
0
36,156
C
T
T
T
T
C
T
C
T
C
T
G
C
A
G
C
A
G
A
T
C
C
A
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A
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C
C
A
G
A
G
C
T
C
T
A
C
C
T
C
G
A
T
C
C
T
T
T
C
T
G
C
C
C
T
C
C
G
G
G
T
T
T
C
T
0.029354
0.019569
0.050881
0.015656
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0.021526
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0.054795
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0.037182
0.033268
0.027397
0.029354
0.062622
0.041096
0.048924
0.011742
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0
0.027397
0.04501
0.031311
0.023483
0.046967
0.035225
0.048924
0.021526
0.02544
0.029354
0
36,157
T
T
T
T
A
A
A
A
T
A
C
C
C
A
C
C
A
T
G
G
C
T
C
C
A
C
A
C
C
A
G
C
C
G
C
A
G
A
A
G
G
A
C
G
C
C
T
C
C
C
A
G
A
G
A
T
T
C
C
A
G
C
G
A
C
T
0.091977
0.021526
0.033268
0.04501
0.027397
0.02544
0.003914
0.035225
0.052838
0.019569
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0.027397
0.027397
0.033268
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0.009785
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0.017613
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0.039139
0.015656
0.023483
0.029354
0.037182
0.021526
0.033268
0.035225
0
36,158
A
A
G
C
T
G
G
G
A
T
T
T
C
C
A
A
T
G
G
A
C
T
C
T
C
T
G
A
A
A
A
G
T
G
A
A
G
A
T
C
T
T
T
C
A
A
A
G
T
T
T
T
A
G
G
G
T
C
A
G
T
T
C
T
T
C
0.068493
0.017613
0.054795
0.046967
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0.033268
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0.052838
0.023483
0.031311
0.046967
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0.027397
0.035225
0.037182
0.041096
0.031311
0.005871
0
0.005871
0.02544
0.027397
0.04501
0.027397
0.019569
0.009785
0.035225
0.029354
0.046967
0.037182
0
36,159
T
G
G
T
C
C
A
T
G
C
G
T
A
T
C
T
C
T
G
A
A
T
G
T
G
A
A
A
G
G
A
C
C
G
T
G
T
G
T
G
T
C
A
G
A
A
A
A
T
G
T
A
A
G
G
A
A
A
A
C
A
A
C
T
C
T
0.04501
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0.035225
0.027397
0.050881
0.027397
0.005871
0.039139
0.048924
0.017613
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0.043053
0.027397
0.021526
0.017613
0.041096
0.013699
0.035225
0.058708
0
36,160
G
G
A
G
C
C
A
T
C
C
A
G
T
T
T
G
T
C
A
C
G
C
A
T
T
A
T
C
A
G
C
A
C
T
C
C
A
G
C
A
C
C
C
A
G
A
G
A
C
G
C
A
T
C
C
G
C
G
T
G
A
C
C
A
C
G
0.058708
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0.039139
0.031311
0.04501
0.023483
0.011742
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0.041096
0.021526
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0.013699
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0.039139
0.02544
0.031311
0.027397
0.035225
0.013699
0.027397
0.048924
0
36,161
C
T
T
T
T
T
G
A
C
A
A
G
G
T
C
T
C
A
C
C
C
T
G
T
C
G
C
C
C
A
G
G
C
T
T
G
A
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
T
C
G
G
C
T
C
A
C
C
A
C
T
0.099804
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0.031311
0.043053
0.031311
0.019569
0.031311
0.02544
0
36,162
G
C
C
C
A
G
G
C
T
T
G
A
G
T
G
C
A
G
T
G
G
C
A
T
G
A
T
C
T
C
G
G
C
T
C
A
C
C
A
C
A
A
C
C
T
G
C
G
T
C
T
C
C
G
G
G
C
T
C
A
A
G
T
G
A
T
0.099804
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0.019569
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0.031311
0.046967
0.027397
0.019569
0.033268
0.02544
0
36,163
T
G
A
A
G
A
A
T
G
G
T
T
C
T
G
G
G
G
A
C
A
T
G
T
A
T
C
C
G
G
G
A
C
C
T
G
C
C
A
G
G
C
T
C
C
C
A
G
C
A
G
A
C
A
C
T
G
T
C
T
T
T
A
C
A
T
0.058708
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0.02544
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0.039139
0
36,164
C
C
T
C
G
C
C
A
T
C
A
T
C
C
A
C
T
T
T
C
T
G
T
C
T
T
C
C
C
C
T
A
C
G
A
G
G
T
C
C
A
T
G
A
G
G
T
C
A
A
G
C
T
C
T
G
G
G
G
A
G
A
C
A
A
T
0.029354
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0.031311
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0.041096
0.037182
0.039139
0.009785
0.015656
0.04501
0
36,165
C
C
T
G
G
G
G
G
A
G
A
G
G
C
C
A
G
C
A
G
A
G
C
T
A
A
G
G
A
T
G
A
C
C
T
C
A
C
C
C
C
C
T
T
C
C
A
G
C
A
G
G
A
T
T
T
C
C
T
G
G
G
A
T
G
T
0.04501
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0.033268
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0.054795
0.021526
0.023483
0.023483
0.050881
0.017613
0.021526
0.04501
0
36,166
T
G
A
A
G
T
T
G
C
C
T
T
A
T
G
C
C
A
T
T
T
C
A
A
C
A
G
C
C
A
A
G
T
C
G
G
A
G
G
C
T
C
A
G
C
T
T
G
A
A
G
A
A
C
T
G
G
C
C
C
A
G
A
T
G
A
0.058708
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0
0.021526
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0.029354
0.019569
0.027397
0.033268
0.023483
0.04501
0.043053
0
36,167
G
G
C
C
G
C
G
G
T
G
G
A
G
G
C
C
G
C
C
A
T
G
T
C
T
G
C
A
G
C
A
G
T
C
G
A
C
C
T
C
T
G
G
A
C
A
C
C
T
G
T
C
C
C
C
G
G
C
A
C
G
G
A
C
G
C
0.021526
0.019569
0.031311
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0.017613
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0.02544
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0
0.019569
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0.041096
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0.046967
0.060665
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0.058708
0.029354
0.029354
0.035225
0.062622
0.056751
0.005871
0.001957
0.029354
0
36,168
G
G
A
A
C
T
T
G
C
A
G
G
A
C
T
G
A
C
C
T
T
T
G
A
C
C
T
C
T
C
G
C
T
T
G
A
G
C
C
G
T
G
A
C
G
G
A
G
G
C
G
G
C
A
C
C
G
T
T
T
C
C
A
T
G
A
0.021526
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0.029354
0.019569
0.019569
0.046967
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0
0.019569
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0.054795
0.027397
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0.02544
0.041096
0.04501
0.058708
0.064579
0.007828
0.003914
0.02544
0
36,169
G
T
C
A
G
C
A
C
G
G
C
G
T
T
A
C
C
C
A
C
C
T
C
A
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C
C
G
C
A
G
C
T
C
C
A
G
G
A
C
G
C
C
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C
A
C
T
C
C
A
C
G
C
G
C
T
G
C
C
G
C
A
A
G
A
0.023483
0.019569
0.02544
0.005871
0.013699
0.033268
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0.019569
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0
0.015656
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0.031311
0.062622
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0.027397
0.043053
0.048924
0.048924
0.062622
0.005871
0.005871
0.023483
0
36,170
C
A
G
A
G
C
C
A
C
T
C
G
T
C
C
T
C
G
C
C
T
G
G
T
C
A
T
C
C
C
A
G
T
T
C
C
G
G
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G
G
C
T
G
A
C
C
T
G
G
G
G
A
T
G
C
G
C
C
C
T
G
G
A
C
C
0.02544
0.023483
0.027397
0.015656
0.011742
0.029354
0.031311
0.023483
0.02544
0.046967
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0.031311
0.037182
0.054795
0.04501
0.058708
0.007828
0.009785
0.019569
0
36,171
G
A
G
G
A
C
G
A
G
T
G
G
C
T
C
T
G
T
C
G
A
G
C
C
G
T
G
G
C
G
C
C
C
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G
C
A
A
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G
G
A
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A
G
A
A
C
G
G
A
G
C
T
C
C
A
A
T
C
T
G
G
G
0.023483
0.019569
0.02544
0.027397
0.007828
0.029354
0.031311
0.023483
0.02544
0.043053
0.054795
0.005871
0.009785
0.023483
0.023483
0.02544
0.050881
0.043053
0.046967
0.033268
0.029354
0.054795
0.017613
0.052838
0.02544
0.037182
0.056751
0.048924
0.052838
0.009785
0.023483
0.017613
0
36,172
C
A
G
A
A
G
G
A
A
T
A
C
A
C
T
G
T
C
A
G
T
G
C
A
G
A
C
A
A
G
A
A
C
G
A
G
A
A
A
A
T
C
T
A
A
G
C
A
A
G
A
A
G
A
G
A
A
A
A
A
A
T
A
A
A
T
0.086106
0.041096
0.052838
0.039139
0.048924
0.017613
0.011742
0.039139
0.054795
0.011742
0.035225
0.019569
0.02544
0.033268
0.033268
0.037182
0.037182
0.039139
0.011742
0.007828
0.005871
0.001957
0.013699
0.037182
0.054795
0.017613
0.019569
0.021526
0.043053
0.021526
0.046967
0.033268
0
36,173
G
T
C
C
G
T
G
G
A
A
A
G
G
G
C
C
C
A
A
G
T
C
A
A
A
G
C
A
C
T
C
A
T
G
C
A
G
C
A
G
T
T
G
C
A
T
G
T
T
C
A
C
T
C
T
T
G
A
G
C
A
C
A
C
A
C
0.058708
0.02544
0.04501
0.023483
0.043053
0.027397
0.005871
0.039139
0.031311
0.037182
0.037182
0.023483
0.021526
0.031311
0.033268
0.056751
0.04501
0.046967
0.035225
0.011742
0.005871
0.019569
0.017613
0.037182
0.043053
0.023483
0.035225
0.021526
0.046967
0.009785
0.019569
0.041096
0
36,174
G
G
G
G
C
G
G
A
A
G
T
G
G
A
C
G
G
G
C
T
C
T
T
C
A
G
G
C
A
G
T
A
C
G
A
G
C
G
A
T
G
C
C
A
A
G
C
T
C
C
T
A
C
T
G
C
T
G
A
C
A
T
G
G
T
T
0.052838
0.021526
0.027397
0.039139
0.046967
0.019569
0.005871
0.031311
0.039139
0.039139
0.04501
0.019569
0.027397
0.039139
0.027397
0.031311
0.064579
0.048924
0.029354
0.007828
0.005871
0.003914
0.017613
0.04501
0.031311
0.023483
0.02544
0.04501
0.039139
0.027397
0.029354
0.043053
0
36,175
T
G
G
A
A
A
G
G
C
A
T
C
T
C
T
T
C
A
G
A
T
T
G
G
T
G
A
G
A
A
A
A
T
G
C
C
A
G
T
C
A
C
A
G
C
C
A
G
T
G
T
A
T
T
G
T
C
T
G
A
G
G
A
G
G
C
0.048924
0.029354
0.037182
0.04501
0.062622
0.009785
0.009785
0.043053
0.058708
0.031311
0.015656
0.019569
0.029354
0.031311
0.039139
0.037182
0.062622
0.037182
0.023483
0.013699
0.001957
0.005871
0.009785
0.037182
0.041096
0.033268
0.021526
0.027397
0.031311
0.02544
0.031311
0.048924
0