Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
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G
0.066536
0.023483
0.046967
0.029354
0.048924
0.013699
0.011742
0.037182
0.04501
0.033268
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0.039139
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0.043053
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0.048924
0.033268
0.050881
0.019569
0.041096
0.011742
0.017613
0.039139
0
36,293
G
C
C
C
A
G
C
A
C
C
G
T
G
G
G
C
C
T
G
G
C
A
G
G
C
C
T
G
C
T
C
T
T
C
T
G
G
G
C
T
G
G
C
C
A
G
G
C
A
G
T
G
A
A
C
G
C
C
T
T
G
A
T
A
A
G
0.003914
0.013699
0.019569
0.011742
0.02544
0.039139
0.011742
0.021526
0.033268
0.041096
0.054795
0.009785
0.019569
0.033268
0.017613
0.046967
0.080235
0.07045
0.074364
0.033268
0.005871
0.015656
0.007828
0.043053
0.019569
0.019569
0.060665
0.078278
0.041096
0.017613
0.007828
0.021526
0
36,294
C
C
T
T
C
A
T
C
T
C
T
A
C
A
A
A
C
T
C
A
T
A
G
G
C
G
A
T
C
C
T
T
T
T
G
A
T
A
G
C
C
T
C
C
C
G
G
C
A
G
C
C
C
C
T
G
G
G
A
A
G
G
G
A
A
C
0.017613
0.02544
0.043053
0.009785
0.017613
0.031311
0.003914
0.035225
0.035225
0.037182
0.052838
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0.029354
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0.029354
0.062622
0.084149
0.078278
0.007828
0.003914
0.011742
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0.043053
0.031311
0.021526
0.027397
0.050881
0.060665
0.011742
0.007828
0.031311
0
36,295
C
C
G
A
G
G
T
A
T
G
G
C
A
G
A
G
G
T
G
C
A
A
G
A
C
C
T
A
G
T
C
C
C
C
T
T
T
C
C
T
C
T
A
A
C
T
C
A
C
T
G
C
C
T
A
G
G
A
G
G
C
T
G
G
C
T
0.021526
0.011742
0.031311
0.013699
0.037182
0.033268
0.007828
0.019569
0.043053
0.039139
0.064579
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0.076321
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0.066536
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0.02544
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0.023483
0.031311
0.052838
0.064579
0.048924
0.005871
0.011742
0.009785
0
36,296
C
G
G
A
G
T
C
C
G
T
A
C
C
C
G
G
C
G
C
G
G
C
G
T
G
G
C
C
G
T
A
C
T
C
T
A
T
G
C
A
G
G
G
A
G
A
G
C
G
G
A
G
G
G
G
A
G
G
G
C
T
G
T
G
A
C
0.019569
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0.011742
0.027397
0.029354
0.029354
0.02544
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0.027397
0.031311
0.039139
0.074364
0.048924
0.013699
0.005871
0.023483
0
36,297
A
T
G
T
G
G
A
C
G
A
G
C
A
A
G
G
C
C
T
G
C
A
G
G
A
C
C
T
C
T
T
C
T
C
C
C
A
G
T
T
T
G
G
T
G
G
G
T
G
T
G
T
C
C
C
C
A
A
G
G
G
A
G
C
G
G
0.029354
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0.043053
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0.058708
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0.029354
0.02544
0.041096
0.066536
0.009785
0.001957
0.039139
0
36,298
A
A
T
C
T
G
T
G
C
C
T
G
T
T
T
T
G
G
A
G
A
G
T
C
T
C
A
G
T
A
G
A
C
A
T
T
G
G
C
A
T
C
T
T
A
G
G
G
T
A
G
A
A
T
A
G
T
G
T
A
G
A
T
A
G
T
0.056751
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0.02544
0.021526
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0.031311
0.039139
0.02544
0.04501
0.033268
0
36,299
G
A
A
G
A
A
A
G
C
T
C
A
G
G
A
C
C
A
T
C
C
A
G
T
C
T
G
A
C
C
A
G
C
G
T
T
T
T
A
A
G
A
C
A
A
G
A
T
A
A
C
A
G
G
T
G
C
C
T
A
G
A
G
A
A
G
0.031311
0.02544
0.029354
0.013699
0.029354
0.048924
0.013699
0.021526
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0.046967
0.027397
0.035225
0.037182
0.029354
0.046967
0.011742
0.011742
0.037182
0
36,300
G
A
T
T
C
T
G
G
A
G
A
C
T
C
C
A
G
C
A
T
G
A
G
C
A
A
C
A
G
C
T
C
T
G
A
G
T
T
G
T
C
A
A
T
C
T
C
C
A
G
C
A
G
C
A
T
G
C
C
C
G
T
G
A
T
C
0.013699
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0.017613
0.037182
0.043053
0.046967
0.017613
0.031311
0.027397
0
36,301
T
C
T
G
T
G
T
A
C
T
G
C
T
T
C
A
G
G
A
C
C
A
A
A
T
A
G
C
A
G
A
G
T
G
C
T
C
T
G
A
A
G
G
G
A
A
A
G
A
C
C
A
T
T
T
C
A
G
A
G
G
T
T
T
C
C
0.054795
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0
0.007828
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0.031311
0.027397
0.023483
0.041096
0
36,302
T
C
T
T
T
T
A
T
T
A
C
T
G
A
T
G
T
T
C
A
G
T
G
T
C
T
T
C
C
T
A
A
T
G
G
T
C
T
T
C
A
C
A
T
C
C
T
C
C
T
C
A
G
C
T
C
T
T
C
A
G
A
A
C
C
A
0.043053
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0.043053
0
0.033268
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0.056751
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0.041096
0
36,303
G
T
A
G
A
T
G
C
A
G
T
A
T
A
T
G
G
A
A
T
C
A
G
G
A
A
T
C
T
T
A
A
C
T
T
C
A
T
G
T
G
A
G
C
T
A
T
T
G
G
A
G
T
T
T
T
C
C
T
T
G
C
T
A
T
T
0.048924
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0.011742
0
0.033268
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0.019569
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0
0.001957
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0.048924
0.013699
0.037182
0.011742
0.039139
0.02544
0.043053
0.052838
0
36,304
A
C
T
C
A
C
T
G
A
G
T
T
T
T
C
T
T
C
A
T
C
G
T
C
C
T
G
G
T
C
C
A
C
T
T
C
C
C
G
C
T
G
C
T
G
G
G
A
T
T
C
C
T
G
G
C
G
T
T
T
C
A
G
T
T
T
0.056751
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0.033268
0.019569
0.041096
0.02544
0.035225
0.037182
0
36,305
T
G
T
C
T
C
C
A
G
A
G
A
T
G
C
C
T
C
C
G
A
C
A
C
C
C
C
A
T
C
A
A
T
G
C
T
G
C
T
C
A
G
C
A
A
G
T
C
C
T
C
A
A
A
C
T
C
T
T
G
G
T
G
G
T
C
0.017613
0.017613
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0.011742
0.023483
0.037182
0.007828
0.02544
0.043053
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0.023483
0.017613
0.050881
0.046967
0.046967
0.011742
0.009785
0.041096
0
36,306
C
C
C
T
G
C
G
G
A
C
A
C
C
A
G
A
A
G
G
G
C
G
C
G
C
T
G
A
G
G
A
G
T
T
C
C
C
G
G
G
C
T
T
C
C
C
T
T
C
C
T
G
G
A
A
G
A
C
C
A
G
G
T
T
A
C
0.029354
0.013699
0.027397
0.011742
0.017613
0.027397
0.019569
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0.046967
0.054795
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0.097847
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0.041096
0.029354
0.027397
0.029354
0.066536
0.048924
0.009785
0.005871
0.035225
0
36,307
T
G
C
G
C
T
G
C
C
T
C
A
G
C
C
C
C
A
T
G
A
A
C
C
A
C
C
T
G
T
G
T
C
A
C
A
A
G
G
A
C
T
C
A
G
A
C
T
G
C
T
C
G
G
G
C
A
A
A
A
A
G
C
G
A
T
0.011742
0.013699
0.035225
0.009785
0.027397
0.033268
0.005871
0.027397
0.023483
0.058708
0.064579
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0.019569
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0.007828
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0.021526
0.033268
0.052838
0.050881
0.062622
0.011742
0.009785
0.02544
0
36,308
C
T
T
G
A
T
C
G
T
G
G
T
G
G
T
G
T
T
C
C
T
C
A
T
C
G
C
T
G
G
G
A
C
G
C
T
G
G
T
T
C
T
A
G
A
G
G
C
A
G
C
T
G
T
C
A
C
G
G
G
A
G
G
T
G
T
0.029354
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0.029354
0.033268
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0.009785
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0.031311
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0.041096
0.031311
0.021526
0.035225
0.054795
0.013699
0.021526
0.037182
0
36,309
T
T
G
T
C
C
A
T
T
G
A
A
T
G
G
A
A
C
A
C
G
G
C
C
T
T
T
G
A
C
A
G
T
G
T
C
T
T
G
A
C
C
T
T
T
A
A
C
A
G
G
A
A
C
T
G
T
T
A
A
A
A
G
A
A
G
0.043053
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0.066536
0.013699
0.029354
0.027397
0.007828
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0.035225
0
36,310
C
A
T
A
T
C
A
T
G
T
A
G
A
T
G
C
C
A
A
T
G
A
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C
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A
C
C
A
G
T
C
C
C
G
A
A
A
A
A
G
T
C
A
G
C
A
A
T
A
T
G
A
T
T
T
G
A
A
T
G
C
C
A
0.074364
0.021526
0.046967
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0.021526
0.007828
0.023483
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0
0.015656
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0.043053
0.02544
0.023483
0.021526
0.037182
0.019569
0.027397
0.048924
0
36,311
T
G
C
C
A
A
G
C
G
G
A
T
C
T
T
C
C
C
A
A
T
T
T
C
C
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C
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T
G
G
A
C
A
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G
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C
C
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A
C
T
A
T
T
T
T
G
G
A
C
A
A
A
A
A
G
A
C
A
0.091977
0.031311
0.039139
0.060665
0.04501
0.02544
0.001957
0.019569
0.037182
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0.039139
0.021526
0.027397
0.02544
0.031311
0.015656
0.023483
0.050881
0
36,312
T
A
T
G
T
G
C
C
T
T
C
C
G
G
C
C
A
T
G
C
T
C
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A
T
C
T
T
G
A
C
T
G
A
G
A
T
T
T
T
T
T
G
T
C
T
G
G
T
G
T
T
G
A
T
T
C
T
T
G
T
T
A
T
0.076321
0.041096
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0.033268
0.046967
0.019569
0.013699
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0
0
0.019569
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0.04501
0.02544
0.019569
0.015656
0.027397
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0.02544
0.048924
0
36,313
A
C
C
A
G
A
C
A
A
A
A
A
A
T
C
T
C
A
G
T
C
A
A
G
A
T
C
A
A
G
A
G
C
A
T
G
G
C
C
G
G
A
A
G
G
C
A
C
A
T
A
A
A
A
T
A
T
C
A
T
A
C
C
C
G
T
0.078278
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0.013699
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0
0
0.019569
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0.017613
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0.035225
0.02544
0.048924
0
36,314
A
G
T
T
T
G
G
A
T
C
G
A
A
A
T
A
C
T
G
C
C
T
T
T
G
G
A
T
A
C
A
C
C
T
T
T
C
T
G
G
A
T
G
C
C
C
T
T
T
T
C
T
C
C
A
C
A
G
T
T
G
A
G
A
T
G
0.082192
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0
0.009785
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0.021526
0.023483
0.029354
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0
36,315
G
A
G
A
G
A
G
A
T
G
C
G
C
T
C
A
C
C
T
G
G
A
C
A
G
A
T
G
C
T
G
C
C
T
C
T
G
A
G
G
T
T
C
T
C
C
A
G
C
A
G
G
T
G
C
G
T
C
A
T
G
G
T
G
C
T
0.013699
0.013699
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0.058708
0.043053
0.009785
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0
36,316
G
C
G
T
G
G
C
C
G
A
G
G
T
G
G
C
G
G
C
A
C
A
G
G
C
G
C
G
C
G
C
C
C
G
C
G
G
C
A
T
T
G
A
A
A
T
T
T
A
C
G
C
G
G
T
G
G
G
G
G
T
G
C
A
G
A
0.009785
0.011742
0.017613
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0.023483
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0
0.019569
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0.033268
0.033268
0.068493
0.046967
0.009785
0.005871
0.021526
0
36,317
T
T
T
T
G
G
C
C
A
G
C
T
T
A
T
G
C
A
G
T
T
C
T
T
G
G
A
T
C
C
G
G
C
G
G
T
T
T
G
A
G
C
T
C
T
T
G
A
G
T
A
G
C
T
T
C
A
A
G
A
G
C
G
A
C
T
0.043053
0.02544
0.04501
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0.017613
0.035225
0.062622
0.029354
0.015656
0.02544
0.037182
0
36,318
C
G
G
C
A
G
G
C
T
C
A
G
C
T
C
C
T
C
C
A
A
A
T
G
G
T
T
G
T
C
C
A
T
C
C
C
T
G
C
C
C
A
G
A
G
A
G
A
A
A
A
G
C
T
G
G
T
C
A
G
G
C
C
A
C
C
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0.062622
0.013699
0.017613
0.037182
0
36,319
C
G
G
A
G
G
C
T
G
C
G
G
A
G
G
C
A
A
C
A
G
C
A
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C
A
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C
T
T
T
T
T
G
A
G
G
A
A
A
G
A
A
A
A
A
T
G
T
G
A
G
A
A
A
T
T
C
T
G
C
A
A
G
T
C
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0.033268
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0.013699
0.048924
0
36,320
A
G
C
A
A
G
T
A
T
T
A
T
C
T
T
T
C
T
T
G
T
C
A
T
A
C
C
A
C
C
A
A
T
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A
A
G
A
A
A
A
T
A
A
G
C
C
A
G
G
C
A
G
G
G
G
C
C
A
G
T
T
T
C
T
C
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0.037182
0.04501
0.013699
0.019569
0.021526
0
36,321
G
G
G
G
T
G
T
C
T
T
G
A
A
C
C
T
C
A
G
A
T
G
C
T
C
C
T
T
G
G
G
C
T
C
A
T
C
T
T
T
G
A
G
G
A
T
C
T
T
T
G
G
G
A
A
C
C
C
C
T
T
T
T
A
A
C
0.04501
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0
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0.035225
0.027397
0.021526
0.039139
0.009785
0.029354
0.052838
0
36,322
C
T
C
C
C
A
A
A
T
C
T
A
T
T
G
G
G
C
A
T
G
T
G
C
C
A
A
G
G
A
T
G
T
C
A
T
G
C
T
G
T
C
T
C
C
A
T
G
G
A
G
T
G
G
G
G
G
G
T
G
T
C
T
T
G
C
0.048924
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0
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0.033268
0.02544
0.019569
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0.007828
0.027397
0.048924
0
36,323
T
T
A
A
C
A
T
G
C
A
G
G
C
C
G
T
T
C
T
G
C
A
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C
A
T
C
C
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C
A
T
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T
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A
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A
A
G
T
T
G
T
T
G
G
C
A
T
T
C
C
C
T
T
C
G
C
A
G
C
C
C
C
0.04501
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0.033268
0.031311
0.017613
0.048924
0.04501
0
36,324
G
T
C
C
C
T
T
T
T
C
A
C
A
C
C
A
C
C
C
A
C
A
G
G
G
A
T
C
T
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G
T
T
C
C
A
G
A
A
G
C
T
T
C
C
C
A
G
C
A
C
A
G
G
C
A
G
A
A
G
C
A
T
C
G
0.04501
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0
0.035225
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0.029354
0.031311
0
36,325
G
G
T
C
A
G
A
G
T
T
A
T
G
G
C
A
C
C
C
C
A
G
A
C
T
C
T
G
C
T
G
C
T
T
G
T
C
C
T
G
G
T
T
C
T
C
T
G
T
G
T
G
C
T
G
C
T
G
C
T
G
C
A
G
G
C
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0.060665
0.043053
0.062622
0.011742
0.007828
0.027397
0
36,326
C
T
G
G
C
A
A
T
C
T
G
G
C
G
G
T
C
C
T
G
G
G
C
C
G
A
T
C
A
C
G
G
C
G
A
G
G
G
T
G
T
A
G
A
G
C
T
G
C
A
G
G
G
A
G
G
G
T
G
G
G
T
G
T
C
T
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0
0.019569
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0.021526
0
36,327
C
G
T
C
C
T
C
C
T
C
C
T
C
T
G
G
T
C
C
C
T
C
T
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C
C
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C
T
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G
G
C
T
C
T
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G
G
T
G
G
A
G
G
T
G
C
T
C
C
A
C
T
T
C
C
G
T
A
G
A
C
G
T
G
0.015656
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0.066536
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0.056751
0.027397
0.007828
0.017613
0
36,328
T
C
T
C
A
C
G
A
A
G
G
G
A
T
C
C
T
C
C
T
C
A
G
C
C
C
T
C
A
C
C
T
C
G
G
T
A
C
T
G
G
A
A
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A
C
G
T
C
G
T
G
C
G
T
G
T
C
C
A
A
A
G
G
C
T
0.023483
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0.019569
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0.019569
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0
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0.02544
0
36,329
C
A
G
A
G
G
T
G
A
A
T
G
G
C
C
A
A
G
A
C
G
T
G
G
G
G
A
T
C
A
G
T
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G
G
A
T
T
T
G
C
T
G
G
A
A
A
G
A
A
A
A
A
A
G
G
A
A
G
G
G
T
T
G
A
C
0.04501
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0.050881
0.056751
0.007828
0.017613
0.043053
0
36,330
G
A
G
A
C
C
C
T
G
G
G
G
A
G
T
T
T
T
T
T
C
A
G
T
C
T
C
C
A
T
A
G
T
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G
A
C
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G
A
A
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T
A
A
T
C
T
C
G
A
A
C
A
G
T
C
A
C
T
G
A
G
C
C
0.060665
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0.043053
0.02544
0.02544
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0
0.019569
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0.046967
0.015656
0.027397
0.046967
0
36,331
G
T
A
C
C
G
T
G
G
C
C
T
C
C
C
C
G
G
G
C
C
C
A
G
C
T
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G
G
G
G
G
C
C
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C
A
C
C
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C
C
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G
G
A
G
T
G
G
G
A
T
G
A
G
G
T
C
C
T
T
G
T
T
0.003914
0.017613
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0.027397
0.037182
0.019569
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0.015656
0.056751
0.07045
0.048924
0.015656
0.003914
0.02544
0
36,332
C
C
A
G
A
C
C
C
A
C
C
C
T
G
T
C
A
G
C
T
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C
C
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C
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C
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A
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G
G
T
C
T
A
T
C
T
C
T
G
C
C
A
A
C
G
A
C
C
0.091977
0.023483
0.037182
0.011742
0.029354
0.027397
0.007828
0.031311
0.035225
0.04501
0.050881
0.009785
0.011742
0.017613
0.033268
0.027397
0.064579
0.048924
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0.033268
0.033268
0.041096
0.050881
0.046967
0.009785
0.005871
0.023483
0
36,333
A
G
T
T
G
T
A
G
G
T
A
A
A
A
C
T
C
C
A
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T
C
C
C
C
C
G
G
A
A
A
C
A
C
C
G
G
T
G
C
C
0.050881
0.029354
0.035225
0.013699
0.019569
0.043053
0.033268
0.027397
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0.023483
0.056751
0.037182
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0.033268
0.058708
0.013699
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0.009785
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0.043053
0.021526
0.037182
0.058708
0.039139
0.015656
0.011742
0.031311
0
36,334
T
T
C
T
G
G
A
A
G
A
C
A
T
A
A
A
C
G
C
C
A
G
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C
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A
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A
A
A
C
A
A
T
G
C
A
G
T
G
C
T
T
T
G
C
C
T
0.084149
0.039139
0.041096
0.058708
0.046967
0.015656
0.005871
0.027397
0.031311
0.02544
0.021526
0.062622
0.023483
0.068493
0.052838
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0.027397
0.041096
0.011742
0.001957
0.001957
0.005871
0.017613
0.019569
0.046967
0.017613
0.029354
0.021526
0.027397
0.023483
0.039139
0.046967
0
36,335
T
C
T
T
T
G
T
C
A
C
T
G
A
G
G
T
G
A
T
C
T
C
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A
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A
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C
T
C
T
C
C
A
C
T
G
G
A
T
T
T
T
G
G
T
C
G
0.043053
0.019569
0.046967
0.035225
0.027397
0.029354
0
0.046967
0.054795
0.023483
0.043053
0.021526
0.033268
0.023483
0.043053
0.031311
0.052838
0.048924
0.046967
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0.001957
0.001957
0.013699
0.054795
0.033268
0.027397
0.031311
0.017613
0.048924
0.02544
0.02544
0.043053
0
36,336
G
G
G
T
G
T
G
G
T
C
A
C
G
A
A
G
G
C
G
T
T
G
A
T
G
A
A
G
T
G
C
G
C
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C
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C
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C
C
A
T
G
A
T
G
C
G
C
C
G
G
G
T
C
T
T
G
T
T
0.001957
0.013699
0.021526
0.007828
0.031311
0.048924
0.027397
0.02544
0.017613
0.02544
0.07045
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0.027397
0.021526
0.066536
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0.04501
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0.027397
0.015656
0.037182
0.017613
0.037182
0.072407
0.054795
0.046967
0.015656
0.003914
0.029354
0
36,337
C
C
G
A
G
G
A
G
A
T
G
G
G
G
A
T
G
A
G
G
C
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C
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C
A
G
G
C
T
T
T
G
G
G
T
G
G
A
C
A
A
A
G
G
0.009785
0.017613
0.017613
0.015656
0.035225
0.035225
0
0.011742
0.035225
0.056751
0.064579
0.011742
0.02544
0.033268
0.02544
0.035225
0.080235
0.060665
0.078278
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0.013699
0.056751
0.019569
0.019569
0.046967
0.060665
0.048924
0.009785
0.007828
0.031311
0
36,338
A
T
G
C
T
T
G
G
T
C
T
C
T
T
C
G
A
A
A
G
C
C
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G
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C
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A
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G
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G
A
G
A
G
C
A
T
T
G
A
T
G
G
A
G
T
C
C
A
T
0.027397
0.019569
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0.039139
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0.017613
0.02544
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0.021526
0.035225
0.031311
0.056751
0.043053
0.015656
0.011742
0.035225
0
36,339
G
G
G
C
A
G
G
G
A
G
G
A
G
G
C
C
T
C
C
T
C
A
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C
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A
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C
G
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C
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A
C
C
C
G
A
G
G
T
G
G
G
C
T
C
T
G
T
G
A
T
0.015656
0.009785
0.04501
0.005871
0.035225
0.04501
0.013699
0.021526
0.029354
0.033268
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0.021526
0.02544
0.056751
0.060665
0.052838
0.048924
0.013699
0.015656
0.011742
0.009785
0.052838
0.029354
0.039139
0.029354
0.054795
0.050881
0.009785
0.003914
0.046967
0
36,340
T
C
C
T
G
G
G
C
A
T
C
C
T
C
A
T
G
G
G
T
G
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T
G
C
C
A
G
A
A
G
C
C
A
G
A
G
T
A
A
G
G
G
0.031311
0.013699
0.013699
0.005871
0.039139
0.037182
0.009785
0.027397
0.031311
0.031311
0.078278
0.005871
0.009785
0.037182
0.007828
0.043053
0.082192
0.066536
0.07045
0.013699
0.005871
0.001957
0.009785
0.062622
0.021526
0.039139
0.035225
0.052838
0.066536
0.015656
0.003914
0.029354
0
36,341
T
T
T
C
A
T
C
G
T
A
C
T
G
A
G
A
T
G
C
A
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C
A
C
C
A
G
A
A
A
A
C
C
A
A
A
A
G
A
G
A
0.07045
0.027397
0.07045
0.023483
0.029354
0.027397
0.007828
0.027397
0.058708
0.043053
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0.027397
0.031311
0.056751
0.021526
0.043053
0.04501
0.015656
0.007828
0.009785
0.001957
0.015656
0.039139
0.048924
0.023483
0.04501
0.02544
0.039139
0.019569
0.015656
0.031311
0
36,342
C
C
A
A
G
G
G
C
T
C
C
A
T
G
A
T
G
A
C
T
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C
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T
T
T
C
A
G
G
G
C
C
T
T
C
T
T
G
C
T
T
G
T
0.080235
0.021526
0.048924
0.029354
0.023483
0.029354
0.003914
0.033268
0.043053
0.04501
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0.043053
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0.043053
0.056751
0.033268
0.001957
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0.021526
0.046967
0.035225
0.017613
0.035225
0.031311
0.037182
0.019569
0.021526
0.033268
0
36,343
G
T
G
T
C
A
G
C
C
T
T
G
T
C
A
G
G
T
G
A
A
G
G
T
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C
C
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A
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T
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C
C
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C
G
G
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G
C
G
G
C
C
A
T
G
A
A
C
A
A
A
T
G
G
T
C
C
T
0.031311
0.021526
0.04501
0.011742
0.052838
0.048924
0.003914
0.031311
0.02544
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0.007828
0.009785
0.04501
0.031311
0.068493
0.060665
0.058708
0.031311
0.019569
0.005871
0.005871
0.005871
0.027397
0.037182
0.033268
0.052838
0.046967
0.035225
0.013699
0.007828
0.041096
0
36,344
G
T
G
G
C
A
G
G
C
A
C
G
G
G
T
G
C
A
G
A
C
A
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C
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C
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C
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A
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C
G
C
A
G
G
G
C
A
G
G
C
T
G
C
A
G
C
C
T
C
T
0.023483
0.021526
0.048924
0.015656
0.039139
0.033268
0.003914
0.021526
0.037182
0.033268
0.054795
0.011742
0.023483
0.046967
0.037182
0.041096
0.060665
0.048924
0.037182
0.02544
0.013699
0.007828
0.003914
0.033268
0.04501
0.023483
0.062622
0.054795
0.041096
0.011742
0.003914
0.033268
0
36,345
G
T
T
T
C
A
G
G
G
T
G
G
T
T
C
T
G
G
C
A
G
C
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C
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T
G
A
T
T
G
T
T
C
T
C
T
C
G
A
A
G
T
G
T
T
0.023483
0.021526
0.050881
0.015656
0.04501
0.033268
0.003914
0.019569
0.039139
0.033268
0.052838
0.013699
0.023483
0.048924
0.041096
0.039139
0.052838
0.048924
0.041096
0.021526
0.013699
0.011742
0.007828
0.031311
0.043053
0.027397
0.060665
0.046967
0.043053
0.013699
0.003914
0.027397
0
36,346
C
T
A
T
A
A
A
G
C
T
G
C
C
A
G
C
G
A
G
A
A
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C
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C
T
C
G
A
T
C
T
C
G
T
T
G
G
C
C
T
C
G
G
C
G
0.041096
0.033268
0.039139
0.031311
0.037182
0.031311
0.009785
0.031311
0.046967
0.046967
0.039139
0.023483
0.027397
0.035225
0.031311
0.031311
0.058708
0.046967
0.023483
0.001957
0.015656
0.007828
0.02544
0.041096
0.039139
0.021526
0.031311
0.027397
0.029354
0.023483
0.033268
0.037182
0
36,347
C
A
G
G
T
T
G
A
C
A
G
T
T
A
T
G
T
T
T
T
T
A
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G
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T
G
C
A
A
A
G
T
A
G
T
T
C
A
G
G
T
T
G
T
T
0.043053
0.033268
0.027397
0.011742
0.04501
0.02544
0.021526
0.027397
0.04501
0.041096
0.046967
0.013699
0.021526
0.031311
0.031311
0.043053
0.072407
0.039139
0.033268
0.011742
0.007828
0.017613
0.007828
0.052838
0.033268
0.021526
0.048924
0.037182
0.035225
0.021526
0.007828
0.043053
0
36,348
A
C
C
G
G
C
T
C
C
T
T
C
G
T
C
C
T
T
C
T
C
C
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C
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A
C
T
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G
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G
G
C
C
G
A
G
G
C
C
T
A
T
G
C
T
G
C
C
T
C
0.005871
0.007828
0.041096
0.009785
0.017613
0.02544
0.007828
0.017613
0.033268
0.052838
0.082192
0.005871
0.017613
0.017613
0.031311
0.027397
0.074364
0.066536
0.062622
0.023483
0.015656
0.015656
0.011742
0.056751
0.027397
0.023483
0.043053
0.091977
0.054795
0.009785
0
0.021526
0
36,349
T
C
G
G
G
C
G
A
G
T
G
G
C
C
A
T
G
G
C
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A
C
G
A
G
G
A
C
G
0.001957
0.015656
0.007828
0.007828
0.009785
0.027397
0.017613
0.017613
0.019569
0.054795
0.023483
0.001957
0.013699
0.007828
0.019569
0.017613
0.060665
0.052838
0.078278
0.099804
0.035225
0.121331
0.005871
0.041096
0.007828
0.033268
0.033268
0.117417
0.031311
0.003914
0.003914
0.009785
0
36,350
C
A
G
C
T
C
C
T
G
C
A
A
A
C
A
G
A
C
C
C
C
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C
C
A
C
T
G
C
C
A
C
C
A
C
T
G
C
T
G
C
T
T
0.015656
0.013699
0.035225
0.011742
0.02544
0.033268
0.001957
0.017613
0.058708
0.046967
0.074364
0.003914
0.011742
0.019569
0.017613
0.031311
0.076321
0.068493
0.082192
0.009785
0.009785
0.001957
0.007828
0.078278
0.035225
0.029354
0.029354
0.054795
0.064579
0.003914
0.007828
0.021526
0
36,351
G
A
G
C
T
T
C
G
C
C
T
T
C
C
T
C
A
A
T
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C
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C
C
T
G
T
T
T
G
G
G
G
G
C
T
C
C
C
A
G
G
C
0.005871
0.007828
0.027397
0.005871
0.02544
0.039139
0.019569
0.027397
0.029354
0.043053
0.04501
0.001957
0.017613
0.017613
0.021526
0.068493
0.058708
0.072407
0.09002
0.041096
0.019569
0.009785
0.001957
0.056751
0.019569
0.035225
0.043053
0.068493
0.052838
0
0
0.027397
0
36,352
T
C
C
A
C
A
G
C
C
C
C
G
T
C
C
C
C
T
A
C
C
T
C
G
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G
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C
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C
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A
A
G
A
G
C
G
C
G
A
G
C
T
C
G
C
G
C
G
C
A
0.001957
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0
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0.037182
0.082192
0.07045
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0.001957
0.009785
0
36,353
C
C
C
C
T
A
G
C
C
T
G
A
G
A
G
C
T
G
C
T
C
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T
T
G
C
C
A
T
G
G
T
G
A
T
G
A
G
A
G
T
T
T
0.031311
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0.033268
0
36,354
T
T
T
G
C
T
C
C
C
A
G
C
A
T
C
G
G
G
A
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A
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A
C
T
A
T
T
G
G
C
C
G
G
G
G
A
G
A
G
T
G
G
0.046967
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0.031311
0.019569
0.039139
0.041096
0.046967
0.013699
0.021526
0.033268
0
36,355
G
G
A
C
C
T
C
A
C
G
G
G
T
G
G
C
T
C
C
T
T
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G
A
C
C
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G
G
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C
C
T
T
C
T
C
C
A
G
A
A
A
G
T
G
A
G
G
G
T
G
G
0.023483
0.021526
0.041096
0.021526
0.027397
0.056751
0.003914
0.02544
0.041096
0.027397
0.054795
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0.021526
0.039139
0.046967
0.048924
0.056751
0.072407
0.02544
0.013699
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0.013699
0.04501
0.029354
0.035225
0.039139
0.039139
0.041096
0.009785
0.013699
0.033268
0
36,356
G
G
A
G
A
A
C
G
G
T
C
A
C
G
T
C
C
G
A
G
T
T
C
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T
G
C
T
G
T
C
T
C
T
T
G
T
G
G
C
T
G
C
G
G
T
0.011742
0.029354
0.035225
0.001957
0.02544
0.029354
0.013699
0.039139
0.033268
0.043053
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0.02544
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0.07045
0.056751
0.048924
0.027397
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0.02544
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0.046967
0.035225
0.027397
0.058708
0.056751
0.039139
0.007828
0.005871
0.029354
0
36,357
T
T
A
T
C
C
A
T
G
C
A
A
T
T
G
T
G
T
G
C
T
T
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T
G
T
G
C
T
T
T
C
T
T
G
T
C
T
G
A
G
G
C
G
0.029354
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0.019569
0.043053
0.023483
0.023483
0.029354
0.04501
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0.052838
0.035225
0.04501
0.04501
0.039139
0.04501
0.011742
0.001957
0.043053
0
36,358
G
C
A
T
G
G
C
A
G
G
G
C
C
G
G
G
G
C
G
T
G
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C
T
C
A
G
A
G
C
A
G
A
T
G
T
G
G
G
C
T
C
C
A
T
0.033268
0.017613
0.058708
0.015656
0.031311
0.023483
0.009785
0.02544
0.039139
0.048924
0.048924
0
0.019569
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0.043053
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0.050881
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0.048924
0.017613
0.015656
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0.046967
0.029354
0.029354
0.046967
0.043053
0.003914
0.001957
0.050881
0
36,359
A
A
T
A
G
T
C
T
C
T
T
C
C
C
G
G
A
G
G
T
G
C
C
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T
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G
G
T
A
G
T
C
G
A
T
G
G
A
A
C
C
A
T
T
G
C
0.033268
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0.023483
0.033268
0.041096
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0.039139
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0.052838
0.027397
0.013699
0.013699
0.017613
0.029354
0.035225
0.037182
0.037182
0.039139
0.037182
0.021526
0.015656
0.031311
0
36,360
A
A
G
C
A
A
G
G
A
C
T
T
G
T
T
T
C
G
A
C
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T
T
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A
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T
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T
T
T
A
T
G
C
T
C
C
A
G
T
C
T
C
T
G
G
T
T
0.060665
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0.054795
0.027397
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0.015656
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0.048924
0.019569
0.011742
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0.02544
0.035225
0.033268
0.039139
0.037182
0.037182
0.023483
0.029354
0.027397
0
36,361
C
A
G
A
C
C
C
A
G
T
A
T
C
C
A
T
C
G
G
A
C
C
A
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T
T
G
G
C
A
A
A
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C
C
A
A
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T
A
A
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A
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A
T
C
A
G
C
A
C
G
G
T
T
C
C
C
A
C
C
A
G
C
0.043053
0.035225
0.029354
0.041096
0.039139
0.035225
0.011742
0.029354
0.052838
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0.02544
0.052838
0.058708
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0.011742
0.011742
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0.033268
0.027397
0.031311
0.02544
0.033268
0.027397
0.033268
0.027397
0
36,362
C
C
C
A
C
C
A
C
C
A
A
A
C
T
G
A
G
T
T
C
G
A
G
G
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C
A
C
T
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G
G
C
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T
G
G
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T
C
T
T
T
C
C
C
A
T
T
T
A
T
T
T
C
T
T
C
G
0.062622
0.031311
0.04501
0.048924
0.035225
0.021526
0.003914
0.04501
0.052838
0.023483
0.021526
0.035225
0.033268
0.043053
0.039139
0.039139
0.039139
0.046967
0.021526
0
0.003914
0
0.021526
0.037182
0.050881
0.019569
0.02544
0.017613
0.031311
0.015656
0.035225
0.052838
0
36,363
C
A
A
A
G
C
T
G
A
A
A
C
A
A
A
A
A
A
G
G
A
C
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G
G
T
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G
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G
G
A
A
G
T
G
T
G
T
A
T
G
T
A
T
A
T
A
T
T
T
0.101761
0.033268
0.035225
0.074364
0.062622
0.02544
0.005871
0.027397
0.041096
0.019569
0.017613
0.084149
0.02544
0.02544
0.041096
0.04501
0.023483
0.023483
0.007828
0.007828
0
0.005871
0.031311
0.015656
0.031311
0.015656
0.015656
0.009785
0.013699
0.027397
0.072407
0.033268
0
36,364
C
T
G
G
G
T
C
C
C
C
A
G
G
G
A
C
A
G
A
G
C
A
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C
C
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C
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C
C
A
A
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C
T
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G
T
C
C
T
T
C
T
T
T
T
T
C
C
T
T
G
C
C
G
T
C
A
T
0.050881
0.037182
0.046967
0.046967
0.039139
0.011742
0.005871
0.039139
0.054795
0.027397
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0.029354
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0.043053
0.021526
0.04501
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0.043053
0.003914
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0.019569
0.04501
0.054795
0.02544
0.04501
0.013699
0.046967
0.011742
0.033268
0.033268
0
36,365
A
A
C
C
C
C
A
G
G
G
C
A
C
G
C
C
C
C
G
G
C
C
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A
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A
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T
C
C
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C
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G
C
C
G
C
C
A
G
G
G
A
T
C
C
C
A
C
G
C
T
T
C
T
C
C
C
0.035225
0.011742
0.060665
0.011742
0.033268
0.033268
0.009785
0.011742
0.043053
0.056751
0.058708
0.007828
0.033268
0.013699
0.043053
0.029354
0.060665
0.052838
0.048924
0.02544
0.009785
0.009785
0.001957
0.046967
0.029354
0.035225
0.031311
0.043053
0.060665
0.011742
0.009785
0.029354
0
36,366
G
G
A
G
A
G
G
A
T
C
C
C
C
A
A
G
A
C
C
T
G
T
G
T
G
C
C
A
C
C
T
G
T
C
G
G
A
C
T
G
G
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G
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G
G
C
A
A
G
G
A
A
G
G
A
A
G
T
T
G
A
T
C
A
0.02544
0.015656
0.043053
0.009785
0.029354
0.033268
0.005871
0.019569
0.041096
0.043053
0.072407
0.001957
0.023483
0.027397
0.02544
0.037182
0.066536
0.052838
0.043053
0.027397
0.009785
0.009785
0.009785
0.054795
0.037182
0.033268
0.035225
0.060665
0.058708
0.001957
0.005871
0.039139
0
36,367
A
C
T
G
G
A
G
A
C
A
A
G
C
T
T
T
T
G
T
G
C
T
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G
C
A
A
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A
T
T
T
G
A
A
G
G
A
C
A
C
A
A
G
A
C
C
C
C
0.064579
0.023483
0.054795
0.046967
0.035225
0.019569
0.009785
0.031311
0.043053
0.048924
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0.039139
0.017613
0.02544
0.054795
0.029354
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0.039139
0.009785
0.007828
0.007828
0.005871
0.023483
0.031311
0.050881
0.02544
0.039139
0.027397
0.031311
0.017613
0.021526
0.041096
0
36,368
T
T
C
T
T
T
A
G
A
A
T
C
C
T
G
G
C
C
C
T
C
T
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C
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C
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T
T
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G
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G
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C
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C
A
G
A
C
T
C
C
T
G
A
G
A
G
G
A
A
A
C
C
C
T
0.062622
0.021526
0.035225
0.041096
0.033268
0.017613
0.011742
0.019569
0.043053
0.050881
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0.029354
0.021526
0.043053
0.035225
0.031311
0.015656
0.029354
0.035225
0
36,369
A
A
G
C
G
G
A
A
A
A
G
T
G
A
G
G
A
A
G
G
A
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T
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C
A
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A
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G
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A
A
A
A
A
G
A
A
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A
A
C
A
A
A
A
C
A
A
A
A
0.125245
0.039139
0.046967
0.046967
0.043053
0.017613
0.003914
0.037182
0.033268
0.021526
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0.029354
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0.04501
0.021526
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0.013699
0.005871
0.005871
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0.050881
0.007828
0.015656
0.009785
0.043053
0.033268
0.039139
0.041096
0
36,370
C
A
C
G
T
C
C
A
C
A
T
C
C
T
C
C
T
T
G
G
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C
T
G
G
A
A
G
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A
G
C
C
C
C
A
C
C
0.027397
0.015656
0.046967
0.019569
0.017613
0.021526
0.007828
0.031311
0.035225
0.058708
0.052838
0.007828
0.029354
0.029354
0.033268
0.033268
0.068493
0.058708
0.046967
0.011742
0.007828
0.011742
0.013699
0.046967
0.033268
0.019569
0.048924
0.052838
0.046967
0.009785
0.015656
0.039139
0
36,371
T
T
G
G
G
G
T
G
T
G
G
T
C
A
C
C
T
G
G
G
C
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A
T
C
C
T
G
C
T
G
C
C
T
C
C
A
A
G
C
T
G
G
T
0.050881
0.023483
0.029354
0.019569
0.02544
0.035225
0.017613
0.031311
0.02544
0.027397
0.048924
0.015656
0.023483
0.039139
0.027397
0.043053
0.048924
0.066536
0.052838
0.011742
0.007828
0.02544
0.017613
0.037182
0.021526
0.017613
0.031311
0.060665
0.031311
0.027397
0.023483
0.035225
0
36,372
G
A
C
G
C
T
G
T
C
C
T
G
G
A
A
G
G
C
C
C
C
A
G
A
G
G
T
A
C
G
C
T
C
G
G
C
C
T
C
C
A
A
C
T
C
A
C
T
A
G
G
G
C
T
C
C
G
A
T
G
G
T
C
T
T
G
0.029354
0.019569
0.046967
0.007828
0.021526
0.031311
0.007828
0.027397
0.039139
0.052838
0.062622
0.013699
0.017613
0.019569
0.031311
0.041096
0.064579
0.04501
0.050881
0.021526
0.011742
0.009785
0.009785
0.060665
0.039139
0.015656
0.056751
0.046967
0.050881
0.011742
0.003914
0.031311
0
36,373
A
T
G
G
A
G
G
C
A
T
T
T
G
A
C
A
A
A
C
T
C
C
C
C
A
T
C
G
C
C
C
A
C
T
G
C
T
T
C
C
A
G
G
A
C
G
G
G
C
G
T
G
C
C
C
A
T
C
C
G
C
G
T
C
A
G
0.048924
0.019569
0.027397
0.021526
0.027397
0.043053
0.023483
0.02544
0.019569
0.029354
0.037182
0.005871
0.023483
0.039139
0.029354
0.048924
0.050881
0.058708
0.064579
0.021526
0.023483
0.029354
0.007828
0.02544
0.029354
0.035225
0.041096
0.04501
0.029354
0.015656
0.009785
0.043053
0
36,374
C
T
T
C
T
C
A
C
C
C
T
C
A
G
G
G
T
T
G
G
T
T
A
T
A
C
C
C
A
G
A
A
T
C
T
G
T
T
G
G
G
G
A
C
A
A
G
A
T
T
C
T
T
T
A
T
T
G
T
G
A
T
C
T
T
C
0.035225
0.041096
0.041096
0.02544
0.035225
0.043053
0.009785
0.027397
0.041096
0.011742
0.041096
0.017613
0.037182
0.033268
0.046967
0.027397
0.041096
0.052838
0.056751
0.019569
0.017613
0.019569
0.009785
0.031311
0.046967
0.02544
0.017613
0.029354
0.039139
0.021526
0.013699
0.043053
0
36,375
G
C
T
G
G
G
A
A
A
T
G
C
G
G
C
C
G
C
C
A
G
G
T
A
C
T
T
C
T
T
C
T
C
A
C
C
C
T
C
A
G
G
G
T
T
G
G
T
T
A
T
A
C
C
C
A
G
A
A
T
C
T
G
T
T
T
0.043053
0.04501
0.041096
0.027397
0.035225
0.041096
0.007828
0.033268
0.043053
0.009785
0.039139
0.017613
0.035225
0.033268
0.046967
0.02544
0.039139
0.054795
0.054795
0.013699
0.015656
0.017613
0.011742
0.033268
0.04501
0.02544
0.013699
0.029354
0.039139
0.021526
0.019569
0.041096
0