row_idx
int64
f_0_ref__32
string
f_1_ref__31
string
f_2_ref__30
string
f_3_ref__29
string
f_4_ref__28
string
f_5_ref__27
string
f_6_ref__26
string
f_7_ref__25
string
f_8_ref__24
string
f_9_ref__23
string
f_10_ref__22
string
f_11_ref__21
string
f_12_ref__20
string
f_13_ref__19
string
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string
f_15_ref__17
string
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string
f_17_ref__15
string
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string
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string
f_20_ref__12
string
f_21_ref__11
string
f_22_ref__10
string
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string
f_24_ref__8
string
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string
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string
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string
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string
f_29_ref__3
string
f_30_ref__2
string
f_31_ref__1
string
f_32_ref_0
string
f_33_ref__1
string
f_34_ref__2
string
f_35_ref__3
string
f_36_ref__4
string
f_37_ref__5
string
f_38_ref__6
string
f_39_ref__7
string
f_40_ref__8
string
f_41_ref__9
string
f_42_ref__10
string
f_43_ref__11
string
f_44_ref__12
string
f_45_ref__13
string
f_46_ref__14
string
f_47_ref__15
string
f_48_ref__16
string
f_49_ref__17
string
f_50_ref__18
string
f_51_ref__19
string
f_52_ref__20
string
f_53_ref__21
string
f_54_ref__22
string
f_55_ref__23
string
f_56_ref__24
string
f_57_ref__25
string
f_58_ref__26
string
f_59_ref__27
string
f_60_ref__28
string
f_61_ref__29
string
f_62_ref__30
string
f_63_ref__31
string
f_64_ref__32
string
f_65_alt
string
f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
5,247
A
A
A
T
C
T
A
T
A
T
A
C
T
T
C
C
T
T
A
C
C
T
G
G
G
A
T
T
G
G
A
A
C
A
A
G
G
T
A
C
T
C
T
T
T
G
A
G
T
G
T
T
C
A
C
A
T
T
G
T
C
A
C
A
T
T
0.086106
0.033268
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0.019569
0.02544
0.02544
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1
5,248
G
T
G
A
A
T
A
T
T
T
T
T
C
T
T
T
G
T
T
T
T
T
T
A
A
G
G
A
A
C
A
C
T
G
T
C
C
A
T
T
G
G
C
A
T
G
G
G
G
A
A
A
T
A
T
A
A
A
C
T
T
G
T
T
T
C
0.138943
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0.04501
0.078278
0.033268
0.013699
0
0.023483
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0.031311
0.046967
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0.013699
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0.037182
0.019569
0
0
0
0.027397
0.017613
0.048924
0.009785
0.019569
0.011742
0.031311
0.017613
0.058708
0.031311
1
5,249
T
G
G
A
A
A
A
A
T
G
G
C
T
T
T
G
A
A
T
C
T
T
T
G
G
C
C
A
G
T
A
C
C
T
C
A
T
G
G
A
T
T
A
G
A
A
G
A
T
T
T
G
C
T
G
A
A
C
C
C
T
A
T
T
G
T
0.125245
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0.046967
0.064579
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0.017613
0
0.035225
0.048924
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0.04501
0.019569
0.02544
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0.017613
0.001957
0.001957
0
0.02544
0.021526
0.048924
0.015656
0.013699
0.013699
0.033268
0.017613
0.048924
0.035225
1
5,250
T
C
C
A
G
T
A
A
C
A
C
C
A
A
T
A
G
G
G
T
T
C
A
G
C
A
A
A
T
C
T
T
C
T
A
A
T
C
C
A
T
G
A
G
G
T
A
C
T
G
G
C
C
A
A
A
G
A
T
T
C
A
A
A
G
T
0.119374
0.033268
0.043053
0.066536
0.033268
0.017613
0
0.035225
0.046967
0.019569
0.017613
0.060665
0.035225
0.037182
0.04501
0.019569
0.027397
0.04501
0.017613
0.001957
0.001957
0
0.027397
0.021526
0.04501
0.015656
0.015656
0.013699
0.033268
0.017613
0.050881
0.035225
1
5,251
C
C
A
T
A
G
A
A
A
A
T
C
T
T
T
C
T
C
C
T
G
C
T
C
A
G
T
G
A
T
T
T
C
A
G
A
G
A
G
A
G
G
A
T
C
T
C
G
T
G
T
A
G
A
A
A
T
T
G
C
T
T
T
G
A
T
0.138943
0.023483
0.029354
0.09589
0.048924
0.009785
0.001957
0.021526
0.056751
0.027397
0.015656
0.052838
0.027397
0.037182
0.039139
0.013699
0.037182
0.019569
0.005871
0
0.001957
0
0.02544
0.029354
0.04501
0.013699
0.021526
0.005871
0.019569
0.031311
0.066536
0.037182
1
5,252
A
C
C
T
G
T
G
A
C
T
C
C
A
T
A
G
A
A
A
A
T
C
T
T
T
C
T
C
C
T
G
C
T
C
A
G
T
G
A
T
T
T
C
A
G
A
G
A
G
A
G
G
A
T
C
T
C
G
T
G
T
A
G
A
A
G
0.142857
0.023483
0.033268
0.09589
0.046967
0.009785
0.001957
0.021526
0.054795
0.029354
0.013699
0.052838
0.027397
0.039139
0.039139
0.013699
0.035225
0.019569
0.005871
0
0.001957
0
0.02544
0.027397
0.04501
0.011742
0.023483
0.005871
0.017613
0.031311
0.066536
0.037182
1
5,253
A
C
C
T
G
T
G
A
C
T
C
C
A
T
A
G
A
A
A
A
T
C
T
T
T
C
T
C
C
T
G
C
T
C
A
G
T
G
A
T
T
T
C
A
G
A
G
A
G
A
G
G
A
T
C
T
C
G
T
G
T
A
G
A
A
A
0.142857
0.023483
0.033268
0.09589
0.046967
0.009785
0.001957
0.021526
0.054795
0.029354
0.013699
0.052838
0.027397
0.039139
0.039139
0.013699
0.035225
0.019569
0.005871
0
0.001957
0
0.02544
0.027397
0.04501
0.011742
0.023483
0.005871
0.017613
0.031311
0.066536
0.037182
1
5,254
C
T
T
A
C
C
T
G
T
G
A
C
T
C
C
A
T
A
G
A
A
A
A
T
C
T
T
T
C
T
C
C
T
G
C
T
C
A
G
T
G
A
T
T
T
C
A
G
A
G
A
G
A
G
G
A
T
C
T
C
G
T
G
T
A
C
0.142857
0.023483
0.033268
0.09589
0.046967
0.009785
0.001957
0.023483
0.054795
0.029354
0.013699
0.052838
0.027397
0.039139
0.039139
0.013699
0.033268
0.019569
0.005871
0
0.001957
0
0.02544
0.027397
0.043053
0.011742
0.023483
0.005871
0.017613
0.033268
0.068493
0.035225
1
5,255
T
T
T
T
A
G
C
A
C
T
T
A
C
C
T
G
T
G
A
C
T
C
C
A
T
A
G
A
A
A
A
T
C
T
T
T
C
T
C
C
T
G
C
T
C
A
G
T
G
A
T
T
T
C
A
G
A
G
A
G
A
G
G
A
T
T
0.136986
0.023483
0.031311
0.097847
0.046967
0.009785
0.001957
0.021526
0.056751
0.029354
0.013699
0.050881
0.027397
0.039139
0.039139
0.013699
0.035225
0.019569
0.005871
0
0.001957
0
0.02544
0.029354
0.046967
0.011742
0.023483
0.005871
0.017613
0.033268
0.066536
0.037182
1
5,256
A
C
A
C
A
A
A
C
T
A
G
A
G
T
C
A
C
A
C
A
C
C
T
T
T
T
G
T
G
T
T
T
C
A
T
C
C
T
T
C
T
T
C
T
C
C
T
G
T
T
T
G
A
G
A
A
T
G
T
C
A
G
T
T
A
T
0.082192
0.031311
0.037182
0.056751
0.052838
0.011742
0.007828
0.037182
0.04501
0.023483
0.031311
0.048924
0.02544
0.033268
0.04501
0.039139
0.041096
0.027397
0.007828
0
0.007828
0
0.023483
0.035225
0.035225
0.023483
0.037182
0.021526
0.02544
0.017613
0.046967
0.041096
1
5,257
C
G
T
T
C
A
T
G
T
G
C
T
G
G
A
T
A
C
T
G
T
G
T
A
G
C
T
A
C
C
T
T
C
A
T
T
T
T
G
G
G
A
A
T
T
G
G
A
G
A
T
C
G
T
C
A
C
A
A
T
A
G
T
A
A
A
0.111546
0.046967
0.035225
0.062622
0.058708
0.017613
0.015656
0.023483
0.039139
0.011742
0.017613
0.050881
0.035225
0.050881
0.050881
0.031311
0.02544
0.035225
0.007828
0
0.007828
0
0.017613
0.013699
0.056751
0.019569
0.015656
0.007828
0.027397
0.019569
0.037182
0.048924
1
5,258
T
T
T
C
A
C
C
A
T
G
A
T
G
T
T
A
C
T
A
T
T
G
T
G
A
C
G
A
T
C
T
C
C
A
A
T
T
C
C
C
A
A
A
A
T
G
A
A
G
G
T
A
G
C
T
A
C
A
C
A
G
T
A
T
C
T
0.111546
0.04501
0.037182
0.066536
0.056751
0.017613
0.015656
0.02544
0.039139
0.011742
0.015656
0.052838
0.035225
0.048924
0.050881
0.033268
0.021526
0.035225
0.005871
0
0.007828
0
0.019569
0.013699
0.054795
0.017613
0.015656
0.007828
0.02544
0.019569
0.043053
0.048924
1
5,259
C
A
G
T
T
T
T
A
T
C
T
A
A
G
G
C
T
A
G
G
G
T
C
T
T
T
C
G
A
A
T
G
T
A
T
G
C
A
A
T
G
T
C
A
T
C
A
A
A
A
G
A
T
T
G
T
A
G
T
T
C
T
G
G
C
C
0.072407
0.031311
0.039139
0.062622
0.04501
0.013699
0.001957
0.023483
0.048924
0.041096
0.023483
0.031311
0.035225
0.062622
0.050881
0.021526
0.035225
0.031311
0.001957
0.001957
0.011742
0
0.02544
0.037182
0.04501
0.017613
0.046967
0.017613
0.02544
0.013699
0.035225
0.048924
1
5,260
G
A
C
C
C
T
A
G
C
C
T
T
A
G
A
T
A
A
A
A
C
T
G
A
G
C
A
A
G
A
G
G
C
T
T
T
G
G
A
G
T
A
T
T
T
C
A
T
G
A
A
A
C
A
A
A
T
G
A
A
T
G
A
T
G
T
0.068493
0.033268
0.037182
0.07045
0.046967
0.013699
0
0.02544
0.048924
0.035225
0.021526
0.037182
0.035225
0.060665
0.050881
0.021526
0.039139
0.031311
0.001957
0.001957
0.009785
0
0.023483
0.031311
0.046967
0.015656
0.046967
0.015656
0.023483
0.015656
0.043053
0.046967
1
5,261
T
T
T
G
T
T
G
T
C
C
A
G
C
C
A
C
C
A
T
G
A
T
G
T
G
C
A
T
C
A
T
T
C
A
T
T
T
G
T
T
T
C
A
T
G
A
A
A
T
A
C
T
C
C
A
A
A
G
C
C
T
C
T
T
G
A
0.07045
0.039139
0.037182
0.068493
0.046967
0.015656
0.001957
0.02544
0.04501
0.033268
0.021526
0.039139
0.035225
0.060665
0.048924
0.019569
0.041096
0.031311
0.003914
0.001957
0.009785
0.001957
0.021526
0.02544
0.046967
0.013699
0.046967
0.015656
0.023483
0.017613
0.046967
0.043053
1
5,262
T
T
T
T
T
G
T
T
G
T
C
C
A
G
C
C
A
C
C
A
T
G
A
T
G
T
G
C
A
T
C
A
T
T
C
A
T
T
T
G
T
T
T
C
A
T
G
A
A
A
T
A
C
T
C
C
A
A
A
G
C
C
T
C
T
C
0.068493
0.039139
0.037182
0.068493
0.046967
0.015656
0.001957
0.02544
0.04501
0.033268
0.021526
0.039139
0.035225
0.060665
0.048924
0.019569
0.041096
0.031311
0.003914
0.001957
0.009785
0.001957
0.021526
0.02544
0.046967
0.013699
0.046967
0.015656
0.023483
0.017613
0.046967
0.04501
1
5,263
T
G
G
A
G
T
A
T
T
T
C
A
T
G
A
A
A
C
A
A
A
T
G
A
A
T
G
A
T
G
C
A
C
A
T
C
A
T
G
G
T
G
G
C
T
G
G
A
C
A
A
C
A
A
A
A
A
T
G
G
A
T
T
G
G
T
0.068493
0.039139
0.037182
0.068493
0.046967
0.013699
0.001957
0.027397
0.043053
0.035225
0.019569
0.041096
0.037182
0.060665
0.048924
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0.023483
0.02544
0.04501
0.011742
0.048924
0.015656
0.023483
0.017613
0.046967
0.043053
1
5,264
T
C
C
A
A
T
C
C
A
T
T
T
T
T
G
T
T
G
T
C
C
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G
T
T
T
C
A
T
G
A
A
A
T
A
C
T
C
C
C
0.068493
0.039139
0.035225
0.068493
0.046967
0.013699
0.001957
0.027397
0.043053
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0.02544
0.04501
0.011742
0.048924
0.015656
0.023483
0.017613
0.048924
0.043053
1
5,265
T
C
C
A
A
T
C
C
A
T
T
T
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T
G
T
T
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T
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A
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G
A
A
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T
A
C
T
C
C
A
0.068493
0.039139
0.035225
0.068493
0.046967
0.013699
0.001957
0.027397
0.043053
0.035225
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0.02544
0.04501
0.011742
0.048924
0.015656
0.023483
0.017613
0.048924
0.043053
1
5,266
G
A
A
G
A
T
C
C
A
A
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C
C
A
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T
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T
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C
A
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T
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T
C
A
T
G
A
A
A
T
T
0.07045
0.041096
0.035225
0.066536
0.046967
0.011742
0.001957
0.029354
0.043053
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0.017613
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0.037182
0.060665
0.048924
0.021526
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0.031311
0.003914
0.001957
0.009785
0.001957
0.02544
0.02544
0.04501
0.011742
0.048924
0.015656
0.023483
0.015656
0.050881
0.043053
1
5,267
T
T
A
T
T
T
A
A
A
A
G
A
A
T
T
A
T
G
A
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G
C
T
A
T
C
C
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A
A
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A
A
T
T
A
A
T
T
C
0.144814
0.039139
0.046967
0.093933
0.035225
0.015656
0
0.027397
0.048924
0.021526
0.017613
0.064579
0.013699
0.039139
0.04501
0.009785
0.013699
0.021526
0.007828
0
0
0
0.035225
0.019569
0.052838
0.007828
0.021526
0.007828
0.015656
0.021526
0.082192
0.029354
1
5,268
T
G
T
G
A
A
T
A
G
A
A
C
T
T
C
C
A
G
T
G
A
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T
C
C
A
A
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A
T
A
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G
A
A
G
G
A
C
A
C
0.123288
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0.043053
0.072407
0.031311
0.007828
0.001957
0.041096
0.046967
0.033268
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0.084149
0.029354
0.017613
0.033268
0.021526
0.035225
0.02544
0.009785
0.001957
0
0.003914
0.037182
0.023483
0.037182
0.007828
0.021526
0.015656
0.021526
0.021526
0.074364
0.029354
1
5,269
C
C
A
G
A
A
A
A
A
C
A
G
C
C
C
G
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A
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C
A
T
G
G
T
G
T
G
G
T
C
C
C
G
C
G
G
G
C
G
0.021526
0.019569
0.031311
0.005871
0.021526
0.021526
0.013699
0.013699
0.021526
0.039139
0.023483
0.007828
0.015656
0.033268
0.023483
0.019569
0.02544
0.02544
0.084149
0.117417
0.021526
0.09002
0.001957
0.039139
0.02544
0.021526
0.035225
0.103718
0.039139
0.009785
0.007828
0.019569
1
5,270
A
A
C
A
G
C
C
C
G
G
A
C
C
G
C
G
T
C
A
A
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T
G
G
T
C
C
C
G
C
G
G
G
C
A
G
C
G
G
C
G
G
0.021526
0.019569
0.031311
0.005871
0.021526
0.021526
0.013699
0.013699
0.021526
0.039139
0.021526
0.007828
0.015656
0.033268
0.023483
0.019569
0.02544
0.02544
0.084149
0.119374
0.021526
0.088063
0.001957
0.039139
0.02544
0.021526
0.035225
0.105675
0.039139
0.009785
0.007828
0.019569
1
5,271
T
G
A
A
T
G
C
C
T
T
C
A
T
G
G
T
G
T
G
G
T
C
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T
G
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C
C
C
A
G
G
A
G
A
A
C
C
C
C
A
A
G
A
T
G
G
0.021526
0.019569
0.031311
0.007828
0.019569
0.019569
0.013699
0.013699
0.021526
0.043053
0.015656
0.009785
0.015656
0.037182
0.02544
0.017613
0.027397
0.029354
0.076321
0.119374
0.021526
0.088063
0.003914
0.035225
0.02544
0.019569
0.039139
0.111546
0.033268
0.009785
0.007828
0.019569
1
5,272
T
C
T
C
C
G
A
C
A
A
A
A
G
T
T
T
C
C
A
C
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C
C
G
A
G
T
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G
T
G
C
A
T
C
T
T
G
G
G
G
G
0.019569
0.021526
0.029354
0.007828
0.021526
0.023483
0.015656
0.013699
0.019569
0.046967
0.013699
0.009785
0.015656
0.041096
0.023483
0.021526
0.033268
0.035225
0.064579
0.109589
0.019569
0.097847
0.003914
0.027397
0.027397
0.019569
0.041096
0.107632
0.029354
0.009785
0.007828
0.021526
1
5,273
G
A
A
G
C
G
G
C
C
G
T
T
C
A
T
C
G
A
C
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A
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C
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C
A
T
G
A
A
G
G
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G
C
A
C
C
C
G
G
A
T
T
C
0.019569
0.02544
0.027397
0.007828
0.017613
0.027397
0.019569
0.013699
0.017613
0.054795
0.015656
0.009785
0.015656
0.041096
0.023483
0.021526
0.043053
0.039139
0.060665
0.09589
0.019569
0.088063
0.007828
0.02544
0.027397
0.019569
0.050881
0.091977
0.029354
0.011742
0.009785
0.021526
1
5,274
T
C
A
T
G
A
G
C
G
T
C
T
T
G
G
T
T
T
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C
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G
G
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G
C
T
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T
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T
G
T
G
C
A
G
C
G
0.017613
0.021526
0.02544
0.009785
0.017613
0.029354
0.021526
0.009785
0.019569
0.056751
0.017613
0.009785
0.017613
0.04501
0.021526
0.02544
0.046967
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0.052838
0.088063
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0.091977
0.007828
0.02544
0.02544
0.019569
0.058708
0.086106
0.029354
0.011742
0.009785
0.023483
1
5,275
A
C
T
G
A
A
T
T
T
T
A
A
A
T
T
T
T
T
T
C
T
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C
G
T
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T
A
G
C
A
G
T
G
G
A
A
G
A
A
G
A
C
T
G
A
T
0.093933
0.021526
0.027397
0.060665
0.031311
0.017613
0.009785
0.033268
0.046967
0.023483
0.02544
0.033268
0.033268
0.052838
0.02544
0.021526
0.033268
0.037182
0.019569
0.013699
0.007828
0.005871
0.035225
0.033268
0.035225
0.017613
0.019569
0.037182
0.021526
0.031311
0.048924
0.04501
1
5,276
A
C
A
A
G
C
A
G
A
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G
A
A
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C
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G
T
G
A
A
A
G
T
G
T
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G
G
T
C
A
T
G
G
G
0.058708
0.037182
0.048924
0.023483
0.043053
0.027397
0.003914
0.043053
0.050881
0.02544
0.033268
0.013699
0.021526
0.046967
0.037182
0.043053
0.048924
0.048924
0.023483
0.003914
0.003914
0.005871
0.013699
0.041096
0.046967
0.023483
0.035225
0.027397
0.031311
0.013699
0.02544
0.048924
1
5,277
G
C
A
G
G
A
A
C
T
G
G
G
G
G
T
T
T
A
T
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C
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C
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A
A
C
A
T
T
G
A
C
T
T
C
T
T
A
C
T
G
0.088063
0.041096
0.041096
0.027397
0.046967
0.02544
0.003914
0.043053
0.04501
0.023483
0.033268
0.031311
0.021526
0.037182
0.041096
0.035225
0.046967
0.043053
0.019569
0.005871
0.003914
0.001957
0.023483
0.033268
0.043053
0.02544
0.029354
0.021526
0.035225
0.017613
0.02544
0.039139
1
5,278
G
G
C
T
G
T
A
C
C
T
C
A
G
T
T
T
T
G
T
C
A
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A
C
A
C
G
A
C
C
A
G
C
T
T
C
G
C
A
A
T
C
T
0.072407
0.037182
0.033268
0.046967
0.043053
0.037182
0.023483
0.019569
0.033268
0.019569
0.041096
0.023483
0.019569
0.039139
0.050881
0.035225
0.04501
0.031311
0.023483
0.007828
0.017613
0.009785
0.003914
0.031311
0.043053
0.031311
0.033268
0.027397
0.015656
0.019569
0.023483
0.060665
1
5,279
C
T
G
G
C
G
A
T
C
T
G
C
T
G
C
C
C
A
C
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C
A
T
A
A
T
G
C
A
C
G
G
A
A
A
C
T
T
C
G
T
T
0.064579
0.039139
0.029354
0.043053
0.043053
0.041096
0.02544
0.017613
0.027397
0.021526
0.04501
0.023483
0.017613
0.037182
0.048924
0.039139
0.04501
0.039139
0.029354
0.007828
0.017613
0.009785
0.005871
0.031311
0.039139
0.031311
0.031311
0.035225
0.015656
0.017613
0.023483
0.056751
1
5,280
A
T
G
A
A
G
T
T
A
T
T
G
C
T
A
G
G
A
T
C
T
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G
A
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G
C
A
T
G
G
C
C
C
T
G
C
A
G
A
G
T
T
A
T
G
0.107632
0.023483
0.043053
0.062622
0.02544
0.019569
0.003914
0.041096
0.056751
0.021526
0.031311
0.039139
0.019569
0.035225
0.035225
0.017613
0.037182
0.027397
0.009785
0.005871
0.007828
0.001957
0.039139
0.031311
0.043053
0.015656
0.04501
0.02544
0.019569
0.033268
0.048924
0.02544
1
5,281
G
G
C
A
C
T
G
G
T
C
T
G
A
T
T
G
G
T
C
C
T
C
A
C
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A
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C
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G
G
T
A
C
T
C
C
A
G
C
A
G
C
A
G
C
C
A
T
T
A
0.07045
0.033268
0.035225
0.066536
0.050881
0.015656
0.007828
0.023483
0.052838
0.027397
0.027397
0.037182
0.029354
0.046967
0.043053
0.023483
0.029354
0.033268
0.019569
0.007828
0.005871
0.001957
0.029354
0.037182
0.043053
0.02544
0.019569
0.017613
0.035225
0.015656
0.048924
0.039139
1
5,282
G
G
A
A
G
A
A
A
C
A
T
T
A
C
C
A
A
G
G
T
C
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G
C
C
T
G
C
A
G
G
G
T
G
A
T
G
C
G
C
A
C
G
0.080235
0.046967
0.037182
0.052838
0.043053
0.02544
0.013699
0.046967
0.037182
0.023483
0.023483
0.035225
0.019569
0.041096
0.031311
0.031311
0.046967
0.029354
0.009785
0.001957
0.009785
0.005871
0.019569
0.027397
0.043053
0.019569
0.031311
0.013699
0.015656
0.031311
0.058708
0.046967
1
5,283
A
C
A
T
G
G
G
T
G
T
G
G
A
G
G
C
A
A
A
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T
T
G
T
T
G
A
0.080235
0.046967
0.050881
0.052838
0.050881
0.017613
0.003914
0.043053
0.048924
0.019569
0.033268
0.033268
0.019569
0.031311
0.039139
0.02544
0.037182
0.02544
0.015656
0.003914
0.003914
0.003914
0.037182
0.021526
0.050881
0.017613
0.021526
0.021526
0.023483
0.02544
0.060665
0.033268
1
5,284
T
C
T
G
T
T
T
A
G
T
C
T
G
C
G
T
C
C
C
A
A
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T
G
A
C
T
A
T
A
T
A
A
T
T
G
T
T
G
A
G
A
C
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.015656
0.062622
0.035225
0.048924
0.046967
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.023483
0.007828
0.023483
0.019569
0.046967
0.052838
1
5,285
T
C
T
G
T
T
T
A
G
T
C
T
G
C
G
T
C
C
C
A
A
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G
A
C
T
A
T
A
T
A
A
T
T
G
T
T
G
A
G
A
A
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.015656
0.062622
0.035225
0.048924
0.046967
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.023483
0.007828
0.023483
0.019569
0.046967
0.052838
1
5,286
C
T
C
A
A
C
A
A
T
T
A
T
A
T
A
G
T
C
A
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G
G
G
A
C
G
C
A
G
A
C
T
A
A
A
C
A
G
A
G
C
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.015656
0.062622
0.035225
0.048924
0.046967
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.021526
0.009785
0.023483
0.019569
0.046967
0.052838
1
5,287
T
C
T
C
T
G
T
T
T
A
G
T
C
T
G
C
G
T
C
C
C
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T
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A
T
T
G
T
T
G
A
T
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.017613
0.062622
0.035225
0.048924
0.04501
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.021526
0.009785
0.023483
0.019569
0.046967
0.052838
1
5,288
T
C
T
C
T
G
T
T
T
A
G
T
C
T
G
C
G
T
C
C
C
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T
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G
A
C
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A
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A
T
A
A
T
T
G
T
T
G
A
G
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.017613
0.062622
0.035225
0.048924
0.04501
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.021526
0.009785
0.023483
0.019569
0.046967
0.052838
1
5,289
T
C
T
C
T
G
T
T
T
A
G
T
C
T
G
C
G
T
C
C
C
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T
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A
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A
A
T
T
G
T
T
G
A
A
0.103718
0.033268
0.02544
0.080235
0.046967
0.011742
0.005871
0.029354
0.035225
0.019569
0.017613
0.062622
0.035225
0.048924
0.04501
0.02544
0.02544
0.023483
0.023483
0.003914
0.005871
0.007828
0.027397
0.021526
0.04501
0.015656
0.021526
0.009785
0.023483
0.019569
0.046967
0.052838
1
5,290
T
T
A
A
C
T
A
T
A
T
T
T
G
A
A
A
A
C
A
G
T
C
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T
T
G
G
G
G
A
C
A
T
C
A
T
T
T
C
A
T
T
C
T
0.064579
0.048924
0.031311
0.04501
0.058708
0.021526
0.013699
0.039139
0.04501
0.015656
0.023483
0.050881
0.031311
0.037182
0.060665
0.035225
0.035225
0.027397
0.013699
0.005871
0.003914
0.003914
0.031311
0.02544
0.033268
0.029354
0.037182
0.009785
0.02544
0.019569
0.031311
0.04501
1
5,291
A
G
T
T
C
T
G
G
T
G
G
C
C
G
A
T
A
G
C
T
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A
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G
A
C
C
A
G
C
C
T
C
G
G
G
T
G
A
G
0.021526
0.023483
0.037182
0.011742
0.019569
0.035225
0.009785
0.023483
0.027397
0.04501
0.046967
0.005871
0.023483
0.02544
0.023483
0.033268
0.050881
0.04501
0.050881
0.050881
0.021526
0.058708
0.023483
0.031311
0.033268
0.021526
0.046967
0.064579
0.043053
0.009785
0.015656
0.019569
1
5,292
T
T
T
T
T
T
T
T
C
A
T
C
T
T
G
T
A
T
C
C
T
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T
G
T
G
G
C
A
T
T
A
A
T
T
G
A
C
T
A
C
A
C
0.084149
0.027397
0.043053
0.052838
0.062622
0.015656
0.001957
0.029354
0.046967
0.017613
0.041096
0.015656
0.02544
0.043053
0.046967
0.023483
0.048924
0.031311
0.027397
0
0.007828
0.001957
0.017613
0.02544
0.050881
0.021526
0.031311
0.023483
0.033268
0.039139
0.02544
0.037182
1
5,293
T
A
T
C
C
T
T
C
A
G
G
T
C
C
T
C
T
T
G
C
C
C
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A
C
T
A
C
A
C
T
C
T
G
G
A
A
T
T
C
C
T
G
A
G
0.084149
0.027397
0.04501
0.052838
0.058708
0.017613
0.001957
0.031311
0.043053
0.013699
0.04501
0.017613
0.027397
0.043053
0.046967
0.023483
0.04501
0.031311
0.027397
0
0.007828
0.001957
0.017613
0.02544
0.050881
0.019569
0.031311
0.023483
0.035225
0.039139
0.027397
0.037182
1
5,294
T
G
T
T
T
C
C
T
G
T
A
C
A
C
C
T
G
T
G
G
C
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C
A
A
T
T
A
A
T
G
C
C
A
C
A
T
T
G
G
C
C
A
T
0.088063
0.029354
0.04501
0.050881
0.056751
0.017613
0.001957
0.033268
0.041096
0.019569
0.043053
0.015656
0.02544
0.041096
0.046967
0.021526
0.048924
0.031311
0.027397
0
0.007828
0.001957
0.015656
0.027397
0.050881
0.017613
0.031311
0.021526
0.035225
0.039139
0.027397
0.039139
1
5,295
T
A
A
T
T
A
T
T
C
G
A
A
C
C
A
C
A
T
T
G
A
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T
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T
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A
C
T
T
C
C
T
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A
A
G
G
A
A
G
G
G
A
G
G
T
0.056751
0.027397
0.050881
0.02544
0.039139
0.031311
0.003914
0.02544
0.041096
0.029354
0.048924
0.027397
0.035225
0.048924
0.035225
0.031311
0.041096
0.035225
0.041096
0.003914
0.011742
0.007828
0.009785
0.043053
0.04501
0.029354
0.023483
0.017613
0.041096
0.011742
0.021526
0.058708
1
5,296
C
A
G
A
G
C
T
C
T
A
T
C
G
A
T
C
A
C
T
G
G
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C
C
A
A
G
G
C
T
T
T
G
G
T
G
C
G
C
T
C
T
T
0.060665
0.023483
0.052838
0.02544
0.035225
0.023483
0.007828
0.02544
0.04501
0.031311
0.04501
0.02544
0.043053
0.046967
0.035225
0.029354
0.039139
0.027397
0.043053
0.005871
0.013699
0.007828
0.013699
0.043053
0.048924
0.029354
0.021526
0.017613
0.039139
0.009785
0.017613
0.066536
1
5,297
C
A
G
A
G
C
G
C
A
C
C
A
A
A
G
C
C
T
T
G
G
C
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G
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A
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C
C
A
G
T
G
A
T
C
G
A
T
A
G
A
G
C
T
C
T
T
0.060665
0.023483
0.052838
0.02544
0.035225
0.023483
0.007828
0.02544
0.04501
0.031311
0.04501
0.02544
0.043053
0.046967
0.035225
0.029354
0.037182
0.029354
0.043053
0.005871
0.013699
0.007828
0.013699
0.043053
0.048924
0.029354
0.021526
0.017613
0.039139
0.009785
0.017613
0.066536
1
5,298
C
C
A
C
A
G
C
C
A
C
T
A
C
C
A
C
A
T
T
G
T
C
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T
G
G
G
G
G
A
T
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A
C
T
C
C
T
T
G
A
A
G
T
0.056751
0.031311
0.039139
0.019569
0.046967
0.031311
0.009785
0.029354
0.046967
0.02544
0.043053
0.023483
0.037182
0.033268
0.035225
0.037182
0.056751
0.048924
0.043053
0.005871
0.009785
0.005871
0.011742
0.037182
0.041096
0.035225
0.017613
0.019569
0.046967
0.013699
0.013699
0.046967
1
5,299
C
A
T
T
C
A
C
T
A
A
G
A
G
A
C
C
T
C
G
C
A
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C
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C
A
A
A
G
T
T
G
T
C
T
G
T
A
A
A
G
A
G
T
T
0.080235
0.021526
0.056751
0.031311
0.035225
0.017613
0.003914
0.04501
0.052838
0.029354
0.050881
0.011742
0.021526
0.017613
0.04501
0.035225
0.033268
0.035225
0.029354
0.003914
0.007828
0.007828
0.02544
0.060665
0.033268
0.017613
0.031311
0.029354
0.043053
0.027397
0.029354
0.029354
1
5,300
C
T
C
A
T
T
C
A
C
T
A
A
G
A
G
A
C
C
T
C
G
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G
T
C
A
A
A
G
T
T
G
T
C
T
G
T
A
A
A
G
A
G
0.080235
0.021526
0.056751
0.029354
0.037182
0.017613
0.003914
0.04501
0.052838
0.029354
0.050881
0.009785
0.021526
0.017613
0.04501
0.035225
0.035225
0.035225
0.029354
0.003914
0.007828
0.007828
0.02544
0.060665
0.033268
0.017613
0.031311
0.029354
0.043053
0.027397
0.029354
0.029354
1
5,301
T
G
A
G
T
A
C
A
T
G
T
G
T
A
G
G
T
T
G
G
A
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C
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C
C
T
T
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C
T
G
T
T
A
C
G
T
G
C
A
T
G
T
G
G
A
T
C
T
T
0.041096
0.019569
0.039139
0.02544
0.046967
0.027397
0.009785
0.023483
0.04501
0.035225
0.054795
0.011742
0.027397
0.037182
0.031311
0.039139
0.054795
0.037182
0.043053
0.015656
0.005871
0.003914
0.021526
0.043053
0.035225
0.023483
0.041096
0.037182
0.041096
0.02544
0.019569
0.037182
1
5,302
G
T
A
G
A
C
C
C
A
T
C
G
G
C
G
G
A
T
G
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C
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G
T
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T
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G
G
T
T
G
G
A
G
A
C
A
C
G
G
G
G
0.029354
0.017613
0.037182
0.029354
0.046967
0.029354
0.009785
0.021526
0.041096
0.039139
0.056751
0.007828
0.023483
0.035225
0.029354
0.046967
0.056751
0.041096
0.046967
0.015656
0.005871
0.003914
0.021526
0.043053
0.037182
0.023483
0.043053
0.043053
0.043053
0.019569
0.017613
0.037182
1
5,303
A
C
A
T
G
T
A
C
T
C
A
G
C
T
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T
C
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T
G
G
G
T
C
T
A
C
C
C
T
C
T
C
A
C
C
C
C
A
G
A
G
G
C
G
T
0.02544
0.021526
0.035225
0.02544
0.048924
0.029354
0.009785
0.023483
0.041096
0.037182
0.058708
0.007828
0.02544
0.035225
0.029354
0.046967
0.058708
0.043053
0.046967
0.015656
0.005871
0.003914
0.02544
0.039139
0.039139
0.023483
0.043053
0.041096
0.04501
0.019569
0.013699
0.035225
1
5,304
G
G
C
T
G
A
C
C
T
C
A
G
G
C
C
C
T
C
G
G
T
A
G
A
T
G
T
T
G
T
G
C
C
G
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G
A
A
T
G
A
G
T
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C
A
G
C
T
C
T
G
G
G
T
G
G
T
G
C
T
G
T
C
A
G
0.019569
0.023483
0.033268
0.02544
0.048924
0.031311
0.013699
0.023483
0.035225
0.037182
0.054795
0.009785
0.02544
0.037182
0.029354
0.046967
0.056751
0.050881
0.054795
0.015656
0.005871
0.003914
0.027397
0.031311
0.037182
0.027397
0.037182
0.043053
0.046967
0.017613
0.015656
0.033268
1
5,305
A
C
A
G
G
T
A
G
G
T
C
T
G
G
T
C
C
A
G
C
A
C
C
A
C
G
T
T
A
T
C
A
C
C
T
G
G
C
T
C
A
G
G
A
T
G
G
G
A
A
G
A
C
C
T
C
T
G
G
G
T
A
A
C
T
A
0.019569
0.02544
0.029354
0.021526
0.039139
0.046967
0.007828
0.031311
0.048924
0.039139
0.050881
0.017613
0.021526
0.021526
0.019569
0.054795
0.074364
0.048924
0.046967
0.007828
0.007828
0.007828
0.017613
0.048924
0.035225
0.033268
0.031311
0.027397
0.033268
0.011742
0.021526
0.050881
1
5,306
C
A
A
G
G
A
A
C
G
A
G
T
G
A
C
A
C
T
G
A
A
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C
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C
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C
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T
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C
C
C
A
G
G
T
G
A
G
A
C
C
T
G
A
T
C
T
A
T
A
C
T
C
0.033268
0.019569
0.021526
0.019569
0.033268
0.04501
0.011742
0.023483
0.043053
0.037182
0.056751
0.017613
0.031311
0.029354
0.015656
0.058708
0.072407
0.050881
0.043053
0.007828
0.009785
0.009785
0.015656
0.050881
0.029354
0.029354
0.043053
0.029354
0.041096
0.005871
0.015656
0.048924
1
5,307
C
T
C
C
C
T
T
C
T
T
T
C
T
T
C
C
A
T
A
G
C
T
G
C
T
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A
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C
C
T
G
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T
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T
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T
T
A
G
G
A
A
C
T
A
C
A
T
A
A
A
G
C
G
C
C
0.043053
0.017613
0.050881
0.037182
0.02544
0.031311
0.003914
0.019569
0.033268
0.048924
0.050881
0.046967
0.021526
0.046967
0.037182
0.019569
0.039139
0.052838
0.043053
0.001957
0.003914
0.009785
0.035225
0.029354
0.048924
0.023483
0.029354
0.021526
0.052838
0.019569
0.019569
0.035225
1
5,308
C
T
T
T
A
T
T
G
G
C
C
T
T
T
T
G
C
A
G
G
T
A
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C
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C
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C
T
G
G
A
G
A
T
C
C
T
G
G
C
T
G
A
G
G
A
A
A
C
A
A
C
0.02544
0.031311
0.027397
0.017613
0.023483
0.033268
0.003914
0.027397
0.056751
0.052838
0.056751
0.019569
0.027397
0.013699
0.035225
0.015656
0.074364
0.056751
0.050881
0.009785
0.007828
0.009785
0.031311
0.060665
0.02544
0.021526
0.035225
0.043053
0.046967
0.019569
0.015656
0.023483
1
5,309
T
T
C
C
C
A
C
T
C
C
C
C
C
A
G
G
T
T
G
T
C
C
C
A
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C
T
G
G
T
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C
C
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A
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G
T
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T
G
A
G
C
C
A
G
C
G
T
G
C
A
G
G
C
A
T
G
G
0.019569
0.031311
0.017613
0.007828
0.039139
0.035225
0.013699
0.019569
0.031311
0.04501
0.062622
0.019569
0.021526
0.041096
0.02544
0.043053
0.074364
0.058708
0.060665
0.007828
0.005871
0.007828
0.021526
0.04501
0.027397
0.015656
0.060665
0.046967
0.046967
0.017613
0.003914
0.02544
1
5,310
A
A
T
A
C
C
A
G
A
C
G
T
A
G
A
A
C
T
G
G
T
A
G
T
G
G
A
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G
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G
C
G
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C
T
G
A
A
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C
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T
G
C
C
A
A
T
G
A
A
G
T
T
G
G
A
G
G
T
G
T
0.02544
0.035225
0.023483
0.015656
0.031311
0.043053
0.011742
0.023483
0.035225
0.033268
0.066536
0.027397
0.017613
0.037182
0.033268
0.037182
0.056751
0.060665
0.056751
0.003914
0.005871
0.005871
0.02544
0.050881
0.02544
0.017613
0.046967
0.043053
0.04501
0.019569
0.013699
0.02544
1
5,311
G
G
A
G
G
G
A
G
C
G
G
C
T
G
A
A
G
C
A
G
A
T
G
C
C
A
A
T
G
A
A
G
T
T
G
G
A
G
G
T
G
A
A
G
A
G
G
G
T
A
G
A
A
A
C
G
A
T
C
T
G
T
A
T
G
C
0.027397
0.039139
0.02544
0.015656
0.031311
0.04501
0.011742
0.027397
0.035225
0.02544
0.068493
0.027397
0.015656
0.035225
0.033268
0.037182
0.054795
0.058708
0.058708
0.003914
0.001957
0.005871
0.027397
0.046967
0.027397
0.017613
0.04501
0.041096
0.04501
0.021526
0.017613
0.02544
1
5,312
G
C
G
G
C
T
A
C
C
T
G
T
C
C
C
G
C
T
C
C
T
T
T
G
A
C
C
T
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G
G
C
C
G
C
C
A
G
T
T
T
C
T
G
T
T
C
C
A
C
T
G
G
A
C
A
G
T
G
A
A
C
T
G
G
T
0.019569
0.023483
0.035225
0.013699
0.021526
0.033268
0.005871
0.033268
0.02544
0.048924
0.066536
0.001957
0.007828
0.023483
0.02544
0.043053
0.07045
0.062622
0.080235
0.011742
0.003914
0.013699
0.021526
0.04501
0.039139
0.019569
0.041096
0.064579
0.043053
0.007828
0.007828
0.039139
1
5,313
C
A
A
T
C
C
T
C
A
G
G
T
G
G
T
G
C
T
G
G
G
G
C
T
G
C
C
C
T
T
C
C
T
G
C
T
G
G
A
G
A
A
C
C
C
C
A
G
C
G
G
C
T
A
C
C
T
G
T
C
C
C
G
C
T
A
0.019569
0.021526
0.037182
0.017613
0.023483
0.037182
0.005871
0.02544
0.021526
0.046967
0.074364
0.003914
0.009785
0.023483
0.027397
0.04501
0.072407
0.062622
0.07045
0.011742
0.003914
0.013699
0.017613
0.041096
0.039139
0.017613
0.04501
0.066536
0.04501
0.007828
0.009785
0.035225
1
5,314
G
A
T
G
A
A
T
G
T
G
C
T
G
C
T
C
T
T
C
G
C
C
C
C
T
G
G
G
T
T
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C
T
G
T
T
T
C
T
T
C
T
C
C
T
C
A
C
A
C
A
G
T
T
T
G
G
C
T
T
C
C
G
T
G
C
0.02544
0.023483
0.035225
0.017613
0.039139
0.029354
0.003914
0.027397
0.048924
0.043053
0.054795
0.017613
0.027397
0.023483
0.037182
0.039139
0.048924
0.054795
0.074364
0.005871
0.003914
0.009785
0.033268
0.058708
0.029354
0.015656
0.021526
0.043053
0.043053
0.021526
0.009785
0.033268
1
5,315
C
C
T
T
T
A
G
G
T
A
C
C
T
C
C
C
T
T
C
G
T
C
T
T
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T
T
C
T
T
C
A
T
G
T
G
C
T
G
C
G
C
C
T
C
T
T
A
C
C
G
T
G
T
C
C
A
C
T
C
C
A
T
C
T
A
0.033268
0.013699
0.04501
0.007828
0.027397
0.04501
0.005871
0.019569
0.043053
0.058708
0.054795
0.007828
0.017613
0.037182
0.031311
0.033268
0.068493
0.060665
0.050881
0.007828
0.005871
0.011742
0.017613
0.04501
0.029354
0.023483
0.050881
0.043053
0.035225
0.027397
0.009785
0.031311
1
5,316
C
A
A
A
G
A
T
G
T
T
C
T
G
G
G
C
C
A
T
G
C
G
G
A
T
G
T
C
A
G
T
G
C
C
T
C
G
G
C
T
G
G
T
G
G
C
A
T
A
G
T
A
C
A
A
C
C
C
C
A
T
A
A
A
G
T
0.021526
0.013699
0.039139
0.005871
0.04501
0.056751
0.007828
0.02544
0.039139
0.039139
0.060665
0.011742
0.021526
0.041096
0.023483
0.04501
0.060665
0.054795
0.04501
0.011742
0.007828
0.007828
0.029354
0.035225
0.02544
0.033268
0.029354
0.041096
0.029354
0.043053
0.009785
0.039139
1
5,317
A
G
A
T
G
T
T
C
T
G
G
G
C
C
A
T
G
C
G
G
A
T
G
T
C
A
G
T
G
C
C
T
C
G
G
C
T
G
G
T
G
G
C
A
T
A
G
T
A
C
A
A
C
C
C
C
A
T
A
A
A
G
A
T
G
G
0.021526
0.013699
0.039139
0.005871
0.04501
0.056751
0.007828
0.02544
0.039139
0.039139
0.060665
0.011742
0.021526
0.039139
0.023483
0.04501
0.060665
0.054795
0.04501
0.011742
0.007828
0.007828
0.029354
0.035225
0.027397
0.033268
0.029354
0.041096
0.029354
0.043053
0.009785
0.039139
1
5,318
G
G
T
G
G
G
C
C
C
A
C
A
C
A
A
G
C
G
G
C
G
C
A
C
C
G
T
T
A
A
G
A
T
G
G
C
G
G
C
T
G
G
G
C
T
G
C
G
G
A
A
A
C
G
C
G
G
C
C
G
G
T
C
C
G
C
0.023483
0.019569
0.021526
0.019569
0.023483
0.037182
0.013699
0.021526
0.02544
0.041096
0.050881
0.005871
0.009785
0.023483
0.013699
0.039139
0.058708
0.048924
0.058708
0.048924
0.013699
0.066536
0.015656
0.043053
0.02544
0.021526
0.046967
0.064579
0.04501
0.015656
0.021526
0.015656
1
5,319
G
A
G
T
G
C
A
T
G
C
A
C
C
T
C
A
G
T
G
G
T
C
T
C
C
G
T
G
T
C
A
C
T
G
C
T
G
C
T
G
G
T
G
G
C
A
C
T
G
T
C
T
C
G
G
A
A
G
C
T
G
G
C
G
A
G
0.017613
0.001957
0.031311
0.011742
0.027397
0.029354
0.011742
0.021526
0.031311
0.054795
0.058708
0.001957
0.013699
0.039139
0.009785
0.046967
0.066536
0.062622
0.068493
0.027397
0.019569
0.007828
0.011742
0.058708
0.029354
0.037182
0.043053
0.060665
0.058708
0.003914
0.005871
0.029354
1
5,320
C
A
G
C
A
C
C
T
A
C
C
G
G
A
T
T
G
T
G
C
C
T
G
G
G
G
G
C
T
A
C
G
C
T
G
T
G
G
T
C
G
G
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A
G
T
G
C
C
T
C
A
G
G
T
C
C
C
A
T
C
G
G
C
T
0.007828
0.009785
0.015656
0.013699
0.023483
0.052838
0.009785
0.019569
0.033268
0.035225
0.074364
0.003914
0.009785
0.015656
0.013699
0.046967
0.086106
0.064579
0.119374
0.015656
0.007828
0.009785
0.013699
0.046967
0.02544
0.039139
0.043053
0.052838
0.048924
0.009785
0
0.031311
1
5,321
T
G
A
G
T
G
T
G
A
G
G
T
A
T
T
C
T
T
T
C
A
G
C
A
C
C
A
C
T
C
C
C
C
G
C
A
A
G
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T
G
G
T
C
T
T
C
A
T
C
T
C
A
G
G
G
A
T
G
C
C
A
G
A
G
T
0.013699
0.011742
0.039139
0.011742
0.027397
0.037182
0
0.019569
0.037182
0.035225
0.074364
0.011742
0.023483
0.031311
0.023483
0.035225
0.066536
0.041096
0.076321
0.02544
0.009785
0.019569
0.011742
0.048924
0.031311
0.02544
0.048924
0.060665
0.043053
0.011742
0.007828
0.039139
1
5,322
C
A
T
C
C
C
C
T
C
T
G
T
T
G
C
T
C
C
A
G
A
T
G
T
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T
G
G
C
C
G
G
T
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C
A
C
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C
A
G
G
A
C
C
T
T
G
G
G
G
C
C
T
T
T
G
C
C
A
A
A
G
A
G
A
0.009785
0.019569
0.02544
0.015656
0.033268
0.023483
0.007828
0.023483
0.041096
0.043053
0.056751
0.011742
0.015656
0.02544
0.021526
0.035225
0.07045
0.060665
0.101761
0.019569
0.013699
0.013699
0.003914
0.064579
0.031311
0.019569
0.039139
0.056751
0.056751
0.011742
0.007828
0.019569
1
5,323
T
C
G
A
A
T
G
C
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C
A
C
T
C
A
G
G
A
C
C
T
T
G
G
G
G
C
C
T
A
0.005871
0.019569
0.02544
0.015656
0.033268
0.023483
0.007828
0.021526
0.043053
0.043053
0.056751
0.011742
0.017613
0.02544
0.021526
0.035225
0.068493
0.060665
0.097847
0.021526
0.015656
0.013699
0.003914
0.066536
0.033268
0.021526
0.039139
0.056751
0.058708
0.009785
0.005871
0.019569
1
5,324
A
T
G
C
C
A
T
C
T
T
C
C
T
G
A
G
C
T
T
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T
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C
C
T
G
A
T
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C
T
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G
T
A
G
G
A
T
0.013699
0.021526
0.041096
0.009785
0.029354
0.033268
0.005871
0.023483
0.050881
0.050881
0.078278
0
0.02544
0.011742
0.027397
0.031311
0.086106
0.062622
0.046967
0.003914
0.003914
0.005871
0.019569
0.056751
0.041096
0.027397
0.033268
0.046967
0.062622
0.011742
0.003914
0.033268
1
5,325
T
G
A
C
C
C
T
T
C
T
G
C
T
G
G
A
G
G
G
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A
C
C
C
A
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T
T
G
C
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C
T
C
A
T
C
C
T
0.021526
0.011742
0.048924
0.009785
0.023483
0.02544
0.003914
0.037182
0.056751
0.04501
0.07045
0.001957
0.017613
0.013699
0.021526
0.027397
0.082192
0.048924
0.066536
0.007828
0.001957
0.005871
0.015656
0.062622
0.041096
0.037182
0.037182
0.037182
0.062622
0.013699
0.007828
0.035225
1
5,326
C
T
T
G
T
G
A
C
C
T
C
C
G
A
G
T
C
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A
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A
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A
C
T
G
G
T
G
T
0.021526
0.019569
0.037182
0.039139
0.02544
0.033268
0.009785
0.033268
0.041096
0.035225
0.056751
0.023483
0.021526
0.033268
0.023483
0.027397
0.048924
0.043053
0.054795
0.009785
0.007828
0.007828
0.021526
0.056751
0.043053
0.037182
0.019569
0.011742
0.064579
0.017613
0.029354
0.04501
1
5,327
T
A
G
C
G
C
C
A
A
G
G
C
G
T
T
G
T
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T
C
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G
A
G
G
G
C
A
C
C
T
C
T
0.076321
0.023483
0.037182
0.007828
0.013699
0.031311
0.017613
0.015656
0.041096
0.033268
0.048924
0.007828
0.009785
0.015656
0.021526
0.017613
0.029354
0.031311
0.054795
0.068493
0.023483
0.058708
0.007828
0.064579
0.029354
0.021526
0.023483
0.072407
0.04501
0.015656
0.019569
0.015656
1
5,328
C
T
G
T
T
G
A
A
G
A
C
A
T
G
A
A
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G
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C
T
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C
A
A
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T
T
T
A
A
T
A
T
A
T
A
C
C
C
0.046967
0.037182
0.04501
0.037182
0.037182
0.031311
0.005871
0.027397
0.037182
0.041096
0.04501
0.023483
0.02544
0.043053
0.052838
0.02544
0.041096
0.046967
0.027397
0.001957
0.003914
0.003914
0.02544
0.039139
0.041096
0.017613
0.027397
0.029354
0.033268
0.021526
0.027397
0.050881
1
5,329
T
T
T
G
C
T
G
C
T
G
T
G
G
T
C
C
A
G
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C
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A
C
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C
T
T
G
A
A
C
T
G
0.037182
0.031311
0.037182
0.02544
0.02544
0.041096
0
0.019569
0.039139
0.039139
0.056751
0.013699
0.02544
0.037182
0.027397
0.029354
0.060665
0.052838
0.080235
0.007828
0.003914
0.007828
0.019569
0.037182
0.039139
0.013699
0.037182
0.041096
0.035225
0.011742
0.029354
0.037182
1
5,330
C
C
T
T
T
C
A
T
A
A
A
C
A
G
C
C
C
A
G
G
T
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C
A
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C
G
A
C
T
T
A
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G
T
A
T
G
T
G
T
T
0.058708
0.023483
0.046967
0.039139
0.046967
0.02544
0.011742
0.029354
0.050881
0.043053
0.043053
0.017613
0.013699
0.031311
0.031311
0.029354
0.050881
0.031311
0.02544
0.005871
0.007828
0.013699
0.019569
0.046967
0.043053
0.021526
0.02544
0.027397
0.027397
0.039139
0.033268
0.039139
1
5,331
A
G
A
T
T
T
C
C
A
C
A
C
A
T
A
C
C
T
A
A
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A
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A
G
G
C
A
C
C
T
G
G
G
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T
G
T
T
T
G
0.058708
0.021526
0.04501
0.039139
0.048924
0.02544
0.011742
0.029354
0.052838
0.039139
0.043053
0.017613
0.013699
0.031311
0.029354
0.029354
0.052838
0.031311
0.02544
0.005871
0.007828
0.013699
0.019569
0.046967
0.043053
0.02544
0.023483
0.027397
0.027397
0.039139
0.033268
0.041096
1
5,332
C
T
G
C
A
C
A
G
T
C
G
C
A
A
T
C
A
C
A
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T
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T
G
T
C
T
T
C
A
T
A
G
A
A
A
G
T
A
A
T
C
A
0.054795
0.033268
0.043053
0.037182
0.054795
0.021526
0.011742
0.031311
0.04501
0.037182
0.043053
0.017613
0.013699
0.033268
0.035225
0.027397
0.062622
0.031311
0.02544
0.003914
0.007828
0.011742
0.013699
0.039139
0.050881
0.023483
0.023483
0.029354
0.027397
0.035225
0.027397
0.046967
1
5,333
A
C
C
C
C
A
A
T
G
A
G
A
C
C
A
C
A
C
C
C
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G
C
G
C
C
C
G
G
T
G
C
A
A
C
T
G
G
T
G
T
T
0.023483
0.021526
0.027397
0.007828
0.039139
0.050881
0.011742
0.027397
0.02544
0.037182
0.050881
0.001957
0.007828
0.033268
0.029354
0.068493
0.058708
0.080235
0.064579
0.017613
0.003914
0.017613
0.017613
0.039139
0.023483
0.035225
0.046967
0.046967
0.052838
0.003914
0.003914
0.023483
1
5,334
G
G
G
A
A
T
G
T
C
T
T
G
T
A
G
C
T
A
T
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A
G
A
A
A
G
A
G
G
C
T
C
T
T
G
A
G
G
A
C
T
0.056751
0.019569
0.039139
0.062622
0.04501
0.023483
0
0.02544
0.046967
0.023483
0.035225
0.052838
0.037182
0.07045
0.039139
0.017613
0.039139
0.021526
0.007828
0.001957
0.003914
0.001957
0.017613
0.035225
0.04501
0.021526
0.037182
0.011742
0.023483
0.035225
0.039139
0.062622
1
5,335
C
A
T
C
T
T
A
A
T
A
T
T
T
T
C
T
G
T
T
T
A
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G
G
T
T
T
T
T
C
A
C
C
T
T
T
C
C
G
A
T
A
0.097847
0.031311
0.039139
0.056751
0.043053
0.017613
0.007828
0.017613
0.041096
0.009785
0.027397
0.039139
0.041096
0.07045
0.037182
0.027397
0.02544
0.052838
0.02544
0.003914
0.005871
0.001957
0.015656
0.015656
0.041096
0.013699
0.02544
0.041096
0.02544
0.013699
0.048924
0.039139
1
5,336
T
T
C
A
G
G
A
C
T
C
T
G
A
T
C
T
C
A
T
T
G
C
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A
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C
C
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C
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C
A
G
C
T
C
C
C
A
T
A
C
A
G
A
G
T
G
A
T
G
0.064579
0.019569
0.052838
0.043053
0.037182
0.02544
0.007828
0.027397
0.046967
0.021526
0.033268
0.039139
0.037182
0.052838
0.033268
0.029354
0.041096
0.058708
0.02544
0.001957
0.007828
0.001957
0.015656
0.019569
0.043053
0.031311
0.021526
0.029354
0.037182
0.015656
0.039139
0.039139
1
5,337
A
A
G
G
A
G
A
A
C
C
T
G
G
A
G
A
A
G
G
T
G
C
C
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C
C
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C
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C
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C
A
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C
A
G
T
G
T
G
G
G
A
T
T
G
G
A
G
A
C
T
T
A
C
T
0.02544
0.023483
0.052838
0.029354
0.033268
0.04501
0.003914
0.031311
0.039139
0.029354
0.056751
0.029354
0.029354
0.033268
0.033268
0.031311
0.039139
0.046967
0.029354
0.017613
0.005871
0.003914
0.031311
0.033268
0.046967
0.023483
0.019569
0.027397
0.048924
0.035225
0.02544
0.039139
1
5,338
G
A
C
C
T
G
C
T
T
G
C
T
G
C
C
G
C
A
T
T
C
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G
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C
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G
C
C
T
T
G
C
A
C
C
A
C
C
C
A
G
C
G
C
T
T
0.013699
0.013699
0.037182
0.013699
0.04501
0.037182
0.021526
0.035225
0.027397
0.048924
0.037182
0.013699
0.019569
0.031311
0.029354
0.064579
0.048924
0.050881
0.041096
0.02544
0.009785
0.021526
0.023483
0.037182
0.021526
0.037182
0.041096
0.037182
0.041096
0.023483
0.013699
0.037182
1
5,339
G
C
T
G
G
C
T
C
A
A
G
T
C
A
T
C
A
A
A
G
A
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A
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C
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C
A
A
G
G
C
A
C
G
T
G
T
C
T
T
T
G
C
C
G
T
0.013699
0.011742
0.033268
0.013699
0.04501
0.031311
0.021526
0.031311
0.02544
0.048924
0.035225
0.007828
0.021526
0.031311
0.033268
0.062622
0.052838
0.054795
0.058708
0.031311
0.009785
0.019569
0.017613
0.035225
0.015656
0.035225
0.04501
0.054795
0.037182
0.019569
0.009785
0.035225
1
5,340
A
T
G
T
C
A
A
G
T
T
A
C
C
C
G
T
G
G
T
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C
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T
G
A
G
T
C
C
C
G
C
T
C
G
G
G
C
A
A
T
C
0.015656
0.015656
0.029354
0.013699
0.041096
0.029354
0.02544
0.023483
0.029354
0.046967
0.041096
0.015656
0.02544
0.033268
0.039139
0.052838
0.062622
0.056751
0.054795
0.023483
0.005871
0.015656
0.019569
0.031311
0.011742
0.035225
0.054795
0.058708
0.033268
0.015656
0.007828
0.035225
1
5,341
T
G
C
T
C
T
C
T
G
C
G
T
C
C
T
G
G
A
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C
C
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C
C
C
A
G
C
G
T
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G
A
G
A
C
A
C
C
A
C
G
T
0.013699
0.011742
0.027397
0.007828
0.039139
0.031311
0.015656
0.023483
0.039139
0.056751
0.052838
0.011742
0.019569
0.027397
0.031311
0.048924
0.074364
0.058708
0.052838
0.013699
0.013699
0.011742
0.009785
0.060665
0.011742
0.039139
0.048924
0.054795
0.041096
0.009785
0.003914
0.037182
1
5,342
A
C
A
T
G
G
G
G
T
C
A
C
T
C
A
G
G
T
C
C
G
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T
G
C
T
A
A
T
C
T
C
A
A
T
C
T
T
G
T
T
T
G
0.052838
0.039139
0.043053
0.02544
0.04501
0.021526
0.001957
0.037182
0.048924
0.029354
0.033268
0.041096
0.023483
0.054795
0.041096
0.035225
0.039139
0.04501
0.019569
0.007828
0.003914
0.005871
0.029354
0.037182
0.041096
0.027397
0.033268
0.033268
0.029354
0.003914
0.023483
0.046967
1
5,343
T
T
G
A
G
T
C
T
G
G
G
C
A
T
T
G
T
T
T
T
C
C
A
G
G
T
A
C
A
A
C
A
T
G
T
T
A
G
C
T
G
T
A
A
G
A
T
T
G
A
T
C
A
A
T
G
C
T
G
C
T
G
T
C
C
C
0.099804
0.029354
0.041096
0.054795
0.037182
0.027397
0.003914
0.027397
0.060665
0.015656
0.037182
0.035225
0.029354
0.033268
0.039139
0.015656
0.027397
0.037182
0.02544
0.007828
0.003914
0.003914
0.023483
0.048924
0.033268
0.015656
0.019569
0.011742
0.043053
0.035225
0.054795
0.021526
1
5,344
C
C
T
T
A
C
C
T
C
A
C
T
A
A
A
T
T
G
A
G
T
C
T
G
G
G
C
A
T
T
G
T
T
T
T
C
C
A
G
G
T
A
C
A
A
C
A
T
G
T
T
A
G
C
T
G
T
A
A
G
A
T
T
G
A
G
0.105675
0.029354
0.043053
0.054795
0.037182
0.029354
0.003914
0.02544
0.064579
0.015656
0.035225
0.035225
0.031311
0.031311
0.037182
0.015656
0.029354
0.033268
0.027397
0.007828
0.003914
0.003914
0.023483
0.04501
0.035225
0.015656
0.019569
0.011742
0.035225
0.035225
0.054795
0.023483
1
5,345
A
C
T
G
C
T
G
G
A
A
G
G
A
C
A
C
G
T
C
G
A
A
A
C
T
G
T
G
C
G
G
G
C
C
T
G
G
G
T
A
G
T
C
G
G
T
G
T
T
G
G
A
G
G
G
G
A
T
G
G
C
G
G
G
T
A
0.035225
0.02544
0.02544
0.02544
0.027397
0.037182
0.027397
0.02544
0.031311
0.039139
0.033268
0.015656
0.017613
0.023483
0.023483
0.04501
0.054795
0.068493
0.054795
0.021526
0.023483
0.029354
0.013699
0.035225
0.041096
0.033268
0.029354
0.035225
0.050881
0.013699
0.015656
0.021526
1
5,346
C
T
T
C
A
C
C
A
C
C
T
C
C
G
T
G
A
C
G
T
G
C
T
C
A
G
C
T
T
T
T
T
T
G
T
A
G
A
C
A
G
G
C
A
T
G
G
C
G
C
G
G
A
T
A
A
C
A
G
C
T
C
C
C
T
C
0.086106
0.029354
0.031311
0.041096
0.029354
0.027397
0.009785
0.031311
0.050881
0.031311
0.033268
0.019569
0.033268
0.031311
0.037182
0.029354
0.056751
0.039139
0.023483
0.009785
0.003914
0.007828
0.021526
0.037182
0.043053
0.021526
0.035225
0.027397
0.027397
0.019569
0.021526
0.052838
1