title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
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Depression of high-threshold calcium currents by activation of human D2 (short) dopamine receptors expressed in differentiated NG108-15 cells. | 1. This study examined the regulation of calcium currents in differentiated NG108-15 cells that had been stably transfected with cDNA encoding the short isoform of the human D2 dopamine receptor. Whole cell calcium currents were recorded by nystatin-perforated patch clamp recording. 2. Transient low-threshold calcium c... | 10.1111/j.1476-5381.1994.tb14852.x | 8,032,591 | D000818:Animals; D002121:Calcium Channel Blockers; D015220:Calcium Channels; D005910:Glioma; D006822:Hybrid Cells; D051379:Mice; D009447:Neuroblastoma; D009638:Norepinephrine; D010455:Peptides; D051381:Rats; D017448:Receptors, Dopamine D2; D014162:Transfection; D014407:Tumor Cells, Cultured; D020866:omega-Conotoxin GVI... | British journal of pharmacology | 1,994 | D002121:Calcium Channel Blockers; D015220:Calcium Channels; D010455:Peptides; D017448:Receptors, Dopamine D2; D020866:omega-Conotoxin GVIA; D009638:Norepinephrine |
Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers. | The aim of this study was to characterize factor(s) in rat bronchoalveolar lavage fluid (BALF) that enhance(s) insulin transport across primary rat alveolar epithelial cell monolayers (RAECM) in primary culture. BALF was concentrated 7.5-fold using the Centricon device and the retentate was used to characterize the fac... | 10.1016/j.ejpb.2008.01.028 | 18,406,118 | D000042:Absorption; D000818:Animals; D001693:Biological Transport, Active; D001992:Bronchoalveolar Lavage Fluid; D018938:Caco-2 Cells; D002460:Cell Line; D002478:Cells, Cultured; D030541:Databases, Genetic; D003911:Dextrans; D004285:Dogs; D004705:Endocytosis; D004847:Epithelial Cells; D016650:Fluorescein-5-isothiocyana... | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V | 2,008 | D003911:Dextrans; D005456:Fluorescent Dyes; D007328:Insulin; D010455:Peptides; C015219:fluorescein isothiocyanate dextran; D014357:Trypsin; D016650:Fluorescein-5-isothiocyanate |
The City Doesn't Sleep: Community Perceptions of Sleep Deficits and Disparities. | While sleep research has focused primarily on aspects of the immediate physical environment and behavioral factors, a growing body of evidence suggests that broader social determinants may play an important role in sleep insufficiency. Yet public health education efforts for sleep largely address "sleep hygiene", with ... | 10.3390/ijerph16203976 | 31,635,232 | D055812:Community-Based Participatory Research; D005260:Female; D017144:Focus Groups; D006801:Humans; D008297:Male; D012893:Sleep Wake Disorders; D064890:Social Determinants of Health; D012931:Social Environment | International journal of environmental research and public health | 2,019 | |
Resistant Starches and Non-Communicable Disease: A Focus on Mediterranean Diet. | Resistant starch (RS) is the starch fraction that eludes digestion in the small intestine. RS is classified into five subtypes (RS1-RS5), some of which occur naturally in plant-derived foods, whereas the others may be produced by several processing conditions. The different RS subtypes are widely found in processed foo... | 10.3390/foods10092062 | 34,574,171 | Foods (Basel, Switzerland) | 2,021 | ||
Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation. | Caspase-1 (CASP1)-mediated classical pyroptosis plays a key role in cancer development and management, however, the role of CASP1 and its regulation has not yet been documented for acute promyelocytic leukemia (APL). Here, we found that CASP1/GSDMD had lower expression in patients with APL and most other subtypes of pr... | 10.1016/j.ejphar.2023.175614 | 36,822,457 | D006801:Humans; D015473:Leukemia, Promyelocytic, Acute; D000069292:Pyroptosis; D020170:Caspase 1; D014212:Tretinoin; D002454:Cell Differentiation | European journal of pharmacology | 2,023 | D020170:Caspase 1; D014212:Tretinoin |
Artificial engineering of secondary lymphoid organs. | Secondary lymphoid organs such as spleen and lymph nodes are highly organized immune structures essential for the initiation of immune responses. They display distinct B cell and T cell compartments associated with specific stromal follicular dendritic cells and fibroblastic reticular cells, respectively. Interweaved t... | 10.1016/S0065-2776(10)05005-4 | 20,510,732 | D000818:Animals; D005109:Extracellular Matrix; D020007:Implants, Experimental; D008198:Lymph Nodes; D008221:Lymphoid Tissue; D051379:Mice; D013154:Spleen; D023822:Tissue Engineering; D054457:Tissue Scaffolds | Advances in immunology | 2,010 | |
Dizziness and vertigo: an epidemiological survey and patient management in the emergency room. | Dizziness and vertigo are frequent causes of presentation at the emergency room, with an incidence in the Vimercate district, Italy, close to 3.5%. The basic management of the "dizzy" patients in the emergency room includes a detailed history and an accurate physical/neurological examination, with the aim to identify "... | 10.1007/s10072-004-0212-9 | 15,045,616 | D002985:Clinical Protocols; D003937:Diagnosis, Differential; D004244:Dizziness; D004636:Emergency Service, Hospital; D006801:Humans; D007558:Italy; D009460:Neurologic Examination; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D014717:Vertigo | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology | 2,004 | |
Glutathione-dependent defense in channel catfish (Ictalurus punctatus) and brown bullhead (Ameriurus nebulosus). | Glutathione-dependent defense against xenobiotic toxicity is a multifaceted phenomenon that has been well characterized in mammals. This study undertakes a comparison of two benthic fish species, the channel catfish and brown bullhead, in terms of characteristics of the glutathione system. The channel catfish, a specie... | 10.1006/eesa.1994.1036 | 7,523,070 | D000818:Animals; D005399:Fishes; D005978:Glutathione; D007059:Ictaluridae; D008099:Liver; D010088:Oxidoreductases; D010545:Peroxides; D013045:Species Specificity; D014812:Vitamin K; D020122:tert-Butylhydroperoxide | Ecotoxicology and environmental safety | 1,994 | D010545:Peroxides; D014812:Vitamin K; D020122:tert-Butylhydroperoxide; D010088:Oxidoreductases; D005978:Glutathione |
Illiteracy among Medicaid recipients and its relationship to health care costs. | Poor literacy is associated with poor health status, but whether illiteracy is also linked to higher medical care costs is unclear. We characterized the literacy skills of 402 randomly selected adult Medicaid enrollees to determine if there was an association between literacy skills and health care costs. Each subject'... | 10.1353/hpu.2010.0272 | 8,043,732 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001130:Arizona; D004522:Educational Status; D005260:Female; D017048:Health Care Costs; D006302:Health Services Research; D006304:Health Status; D006801:Humans; D008297:Male; D008484:Medicaid; D008875:Middle Aged; D011932:Reading; D014481:Unite... | Journal of health care for the poor and underserved | 1,994 | |
Isoindolinone ureas: a novel class of KDR kinase inhibitors. | A series of substituted isoindolinone ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 14c, are potent inhibitors of KDR both enzymatically (< 50 nM) and cellularly < or = 100 nM). A 3D KDR/CDK2/MAP kinase overlay model with several structu... | 10.1016/j.bmcl.2004.06.041 | 15,357,981 | D000818:Animals; D004791:Enzyme Inhibitors; D006801:Humans; D007211:Indoles; D051379:Mice; D041681:NIH 3T3 Cells; D014508:Urea; D040301:Vascular Endothelial Growth Factor Receptor-2 | Bioorganic & medicinal chemistry letters | 2,004 | D004791:Enzyme Inhibitors; D007211:Indoles; D014508:Urea; D040301:Vascular Endothelial Growth Factor Receptor-2 |
Relations among well-being, avoidant coping, and active coping in a large sample of Australian adolescents. | Coping by young people relates to both current and future well-being and is integral to the educational, clinical, and counselling arenas. This paper examined the relations between frequency of use and perceived efficacy of two coping styles (active and negative avoidant), and their relationship to well-being and distr... | 10.2466/PR0.104.3.745-758 | 19,708,401 | D000223:Adaptation, Psychological; D000293:Adolescent; D000294:Adolescent Behavior; D000367:Age Factors; D001294:Attitude to Health; D001315:Australia; D002648:Child; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D010555:Personality Inventory; D011594:Psychometrics; D012737:Sex Factors; D013315:S... | Psychological reports | 2,009 | |
Evidence to support the existence of efficient DNA double-strand break rejoining in a radiosensitive mutant of V79-4 following irradiation with 250 kVp X-rays or neutrons. | The repair of ionising-radiation-induced DNA double-strand break type damage was measured by Kohn neutral elution in an X-ray-sensitive mutant of V79-4, irs1. This was done in order to investigate further the likelihood that irs1 carries a defect which leads to error-prone repair of DNA damage, and not simply a reduced... | 10.1016/0921-8777(90)90056-b | 2,308,591 | D000818:Animals; D002460:Cell Line; D002470:Cell Survival; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA; D004260:DNA Repair; D009154:Mutation; D009502:Neutrons; D011836:Radiation Tolerance; D014965:X-Rays | Mutation research | 1,990 | D004247:DNA |
Prolonged QTc interval predicts poststroke paroxysmal atrial fibrillation. | BACKGROUND AND PURPOSE
Paroxysmal atrial fibrillation (PAF) is often difficult to detect in patients with acute ischemic stroke. We aimed to assess the predictive value of a prolonged QT interval corrected for heart rate (QTc) in PAF detection after acute ischemic stroke.
METHODS
We enrolled 972 patients with acute i... | 10.1161/STROKEAHA.114.006612 | 25,414,174 | D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005260:Female; D006321:Heart; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D020521:Stroke; D013997:Time Factors | Stroke | 2,015 | |
[Assessment of thromboplastins according to the WHO guidelines and the results of external quality control]. | The study was undertaken to assess commercial thromboplastins for compliance to the WHO guidelines and to substantiate the validity of the results of a prothrombin test carried out using these thromboplastins. The test thromboplastins were shown to meet the WHO guidelines for assessment of thromboplastins. Over 5-8 yea... | 21,735,677 | D001778:Blood Coagulation Disorders; D019983:Guideline Adherence; D006801:Humans; D019934:International Normalized Ratio; D017410:Practice Guidelines as Topic; D011517:Prothrombin Time; D011785:Quality Assurance, Health Care; D011786:Quality Control; D015203:Reproducibility of Results; D012426:Russia; D013925:Thrombopl... | Klinicheskaia laboratornaia diagnostika | 2,011 | D013925:Thromboplastin | |
Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2. | During early obesity, pancreatic β cells compensate for increased metabolic demand through a transient phase of insulin hypersecretion that stabilizes blood glucose and forestalls diabetic progression. We find evidence that β cell O-GlcNAcylation, a nutrient-responsive post-translational protein modification regulated ... | 10.1016/j.celrep.2020.107609 | 32,375,037 | D000818:Animals; D001786:Blood Glucose; D003924:Diabetes Mellitus, Type 2; D004721:Endoplasmic Reticulum; D007328:Insulin; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells; D008055:Lipids; D051379:Mice; D009765:Obesity; D011499:Protein Processing, Post-Translational; D053498:Sarcoplasmic Reticulum Calcium-... | Cell reports | 2,020 | D001786:Blood Glucose; D007328:Insulin; D008055:Lipids; D053498:Sarcoplasmic Reticulum Calcium-Transporting ATPases; C506947:Atp2a2 protein, mouse |
Direct and indirect effects of PCV13 on nasopharyngeal carriage of PCV13 unique pneumococcal serotypes in Massachusetts' children. | BACKGROUND
The direct impact of 13-valent pneumococcal conjugate vaccine (PCV13) on colonization with unique PCV13 serotypes and the uptake of vaccine necessary to create indirect protection in nonimmunized children were assessed.
METHODS
Carriage surveillance among children <60 months began in July 2010 at a pediatr... | 10.1097/INF.0000000000000279 | 24,670,957 | D002353:Carrier State; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008404:Massachusetts; D009305:Nasopharynx; D011008:Pneumococcal Infections; D022242:Pneumococcal Vaccines; D015995:Prevalence; D011446:Prospective Studies; D012703:Serotyping; D013296... | The Pediatric infectious disease journal | 2,014 | C538862:13-valent pneumococcal vaccine; D022242:Pneumococcal Vaccines |
Diagnostics of care about environment: A systematic review through nursing taxonomies. | AIM
To analyse the representation of the environment in nursing diagnostic taxonomies.
DESIGN
Systematic scoping review through nursing taxonomies.
METHODS
The first phase identified nursing diagnostic taxonomies by systematic review. The diagnoses were associated with the environment by analysis of terms into the ... | 10.1002/nop2.829 | 33,634,596 | D009733:Nursing Diagnosis; D000072917:Standardized Nursing Terminology; D018875:Vocabulary, Controlled | Nursing open | 2,021 | |
Catabolism of homophthalic acid by a soil bacterium. | A microorganism capable of degrading homophthalic acid as a sole source of carbon was isolated from soil. The strain was tentatively identified as Pseudomonas sp. Oxygen uptake studies were carried out with possible intermediates. Assays for several different enzymes were performed. Homophthalic acid may be metabolized... | 10.1016/0378-1097(89)90058-x | 2,744,421 | D001673:Biodegradation, Environmental; D010101:Oxygen Consumption; D010795:Phthalic Acids; D011549:Pseudomonas; D012988:Soil Microbiology | FEMS microbiology letters | 1,989 | D010795:Phthalic Acids; C060218:homophthalic acid |
Site-directed spin labeling study of subunit interactions in the alpha-crystallin domain of small heat-shock proteins. Comparison of the oligomer symmetry in alphaA-crystallin, HSP 27, and HSP 16.3. | Site-directed spin labeling was used to investigate quaternary interactions along a conserved sequence in the alpha-crystallin domain of alphaA-crystallin, heat-shock protein 27 (HSP 27), and Mycobacterium tuberculosis heat-shock protein (HSP 16.3). In previous work, it was demonstrated that this sequence in alphaA-cry... | 10.1074/jbc.274.10.6305 | 10,037,719 | D000595:Amino Acid Sequence; D003459:Crystallins; D006360:Heat-Shock Proteins; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009169:Mycobacterium tuberculosis; D011960:Receptors, Estrogen; D013113:Spin Labels | The Journal of biological chemistry | 1,999 | D003459:Crystallins; D006360:Heat-Shock Proteins; D011960:Receptors, Estrogen; D013113:Spin Labels |
Femoral neuropathy from iliac muscle hematoma complicating anticoagulant therapy: a surgical emergency. Report of a case. | A case of femoral neuropathy from iliac muscle hematoma occurring during heparin administration, successfully treated by early surgical decompression is reported. Following the evaluation of anatomy, possible pathogenesis and CT scanning findings, the role of early diagnosis is emphasized in the assessment of prognosis... | 3,013,803 | D004630:Emergencies; D005267:Femoral Nerve; D006406:Hematoma; D006493:Heparin; D006801:Humans; D007085:Ilium; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases; D010523:Peripheral Nervous System Diseases; D011859:Radiography | The Italian journal of surgical sciences | 1,986 | D006493:Heparin | |
Radionuclide distribution in soil and undecayed vegetative litter samples in a riparian system at the Savannah River Site, SC. | The aim of this study is to comprehensively investigate radionuclide concentrations in surface soil and un-decayed vegetative litter along four stream systems (i.e. Fourmile Branch, Lower Three Runs, Pen Branch, and Steel Creek) at the Savannah River Site (SRS), Aiken, South Carolina. Soil and litter samples from syste... | 10.1016/j.jenvrad.2018.02.017 | 29,525,107 | D000576:Americium; D002588:Cesium Radioisotopes; D019015:Geologic Sediments; D011005:Plutonium; D011834:Radiation Monitoring; D045483:Rivers; D012990:Soil Pollutants, Radioactive; D013022:South Carolina; D013326:Strontium Radioisotopes; D014875:Water Pollutants, Radioactive | Journal of environmental radioactivity | 2,018 | D002588:Cesium Radioisotopes; D012990:Soil Pollutants, Radioactive; D013326:Strontium Radioisotopes; D014875:Water Pollutants, Radioactive; D011005:Plutonium; D000576:Americium |
New insights into BMP9 signaling in organ fibrosis. | Fibrosis is a common endpoint for chronic organic diseases. Many signaling pathways and cytokines are involved in the development of fibrosis. Recently, bone morphogenetic protein 9 (BMP9), a member of transforming growth factor-beta (TGF-β) superfamily, has been considered as a pivotal regulator in tissue fibrosis, an... | 10.1016/j.ejphar.2020.173291 | 32,574,673 | D000818:Animals; D005347:Fibroblasts; D005355:Fibrosis; D055427:Growth Differentiation Factor 2; D006801:Humans; D015398:Signal Transduction | European journal of pharmacology | 2,020 | D055427:Growth Differentiation Factor 2 |
Programmable Protein-DNA Cross-Linking for the Direct Capture and Quantification of 5-Formylcytosine. | 5-Formylcytosine (5fC) is an epigenetic nucleobase of mammalian genomes that occurs as intermediate of active DNA demethylation. 5fC uniquely interacts and reacts with key nuclear proteins, indicating functions in genome regulation. Transcription-activator-like effectors (TALEs) are repeat-based DNA binding proteins th... | 10.1021/jacs.9b01432 | 31,180,648 | D000818:Animals; D003432:Cross-Linking Reagents; D003596:Cytosine; D004247:DNA; D044127:Epigenesis, Genetic; D016678:Genome; D023281:Genomics; D006801:Humans; D008297:Male; D051379:Mice; D010649:Phenylalanine; D016133:Polymerase Chain Reaction; D000071336:Transcription Activator-Like Effectors | Journal of the American Chemical Society | 2,019 | C476995:3-(4-acetylphenyl)-2-aminopropanoic acid; C560973:5-formylcytosine; D003432:Cross-Linking Reagents; D000071336:Transcription Activator-Like Effectors; D010649:Phenylalanine; D003596:Cytosine; D004247:DNA |
Aortic endostent followed by extended pneumonectomy for T4 lung cancer. | Pulmonary and aortic en bloc resection may be performed with cardiopulmonary bypass support, but is associated with high surgical morbidity and mortality. A 59-year-old man with left lower lobe cancer invading the aorta was considered to be unsuitable for such an extended operation because of previous myocardial infarc... | 10.1016/j.athoracsur.2010.07.045 | 21,256,322 | D000230:Adenocarcinoma; D000077192:Adenocarcinoma of Lung; D001013:Aorta, Thoracic; D019917:Blood Vessel Prosthesis Implantation; D002315:Cardiopulmonary Bypass; D018572:Disease-Free Survival; D005932:Gloves, Surgical; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiven... | The Annals of thoracic surgery | 2,011 | |
Validation of a standardized MRI method for liver fat and T2* quantification. | PURPOSE
Several studies have demonstrated the accuracy, precision, and reproducibility of proton density fat fraction (PDFF) quantification using vendor-specific image acquisition protocols and PDFF estimation methods. The purpose of this work is to validate a confounder-corrected, cross-vendor, cross field-strength, i... | 10.1371/journal.pone.0204175 | 30,235,288 | D050154:Adiposity; D015331:Cohort Studies; D006801:Humans; D008099:Liver; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D011522:Protons; D012015:Reference Standards; D015203:Reproducibility of Results; D014015:Tissue Banks; D006113:United Kingdom | PloS one | 2,018 | D011522:Protons |
[Application of modified double tracks anastomosis in patients with Siewert II-III adenocarcinoma of the esophagogastric junction treated with radical gastrectomy]. | OBJECTIVE
To discuss the effect of modified double tracks anastomosis in patients with type Siewert II-III( adenocarcinoma of the esophagogastric junction(AEG) treated with radical gastrectomy.
METHODS
Clinical data of 763 patients with type Siewert II-III AEG undergoing radical operation in our department from Janua... | 26,013,859 | D000230:Adenocarcinoma; D000713:Anastomosis, Roux-en-Y; D004938:Esophageal Neoplasms; D004943:Esophagogastric Junction; D005743:Gastrectomy; D018530:Gastric Stump; D006801:Humans; D011183:Postoperative Complications; D011788:Quality of Life; D012189:Retrospective Studies; D013274:Stomach Neoplasms; D015996:Survival Rat... | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery | 2,015 | ||
Chronic pain-related disability and use of analgesia and health services in a Sydney community. | OBJECTIVES
To describe the clinical features, antecedents and impact of chronic pain.
DESIGN
Telephone survey of randomly selected household respondents.
SETTING
Northern Sydney Health Area, metropolitan Sydney, July to September 1998.
PARTICIPANTS
2092 English-speaking residents aged 18 years or over.
MAIN OUT... | 10.5694/j.1326-5377.2003.tb05441.x | 12,864,718 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000698:Analgesia; D002908:Chronic Disease; D003695:Delivery of Health Care; D006233:Disabled Persons; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009517:New South Wales; D010146:Pain; D059408:Pain Management; D010147:Pain ... | The Medical journal of Australia | 2,003 | |
Emphysematous pyelonephritis. | OBJECTIVE
The mortality rate among patients with emphysematous pyelonephritis (EPN) is high and the best therapy has long been debated.
MATERIAL AND METHODS
Between January 1993 and December 2004, 26 patients diagnosed with EPN were treated at our hospital. Historical, demographic and laboratory data were obtained fr... | 10.1080/00365590601017451 | 17,469,032 | D000368:Aged; D000900:Anti-Bacterial Agents; D001424:Bacterial Infections; D001786:Blood Glucose; D004322:Drainage; D004646:Emphysema; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007668:Kidney; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011704:Pyelonephritis; D012189:Retrospective Studies; D0140... | Scandinavian journal of urology and nephrology | 2,007 | D000900:Anti-Bacterial Agents; D001786:Blood Glucose |
Point of care transthoracic echocardiography for the prediction of post - spinal anesthesia hypotension in elderly patients with cardiac diseases and left ventricular dysfunction : Inferior vena cava and post-spinal anesthesia hypotension in elderly patients. | In elderly patients with cardiac diseases, changes in cardiovascular physiology diminish cardiovascular reserve and predispose to hemodynamic instability after spinal anesthesia; hence, such patients could be at risk of postoperative complications. Additionally, transthoracic echocardiography (TTE) is used in clinical ... | 10.1007/s10877-023-00981-y | 36,805,418 | D006801:Humans; D000368:Aged; D000775:Anesthesia, Spinal; D013318:Stroke Volume; D014682:Vena Cava, Inferior; D019095:Point-of-Care Systems; D011446:Prospective Studies; D016277:Ventricular Function, Left; D004452:Echocardiography; D007022:Hypotension; D018487:Ventricular Dysfunction, Left; D006331:Heart Diseases | Journal of clinical monitoring and computing | 2,023 | |
Antithrombin III Trento. A 'new' congenital AT III abnormality with a peculiar crossed-immunoelectrophoretic pattern in the absence of heparin. | A family with a new congenital abnormality of antithrombin III (AT III) is presented. 5 members, all females, were affected. The proposita has had several thrombotic manifestations. The other patients, so far, are asymptomatic. Antithrombin activities were all decreased regardless of the method used (chromogenic or clo... | 10.1159/000206364 | 6,208,738 | D000328:Adult; D000906:Antibodies; D058833:Antithrombin Proteins; D000991:Antithrombins; D001760:Bleeding Time; D002648:Child; D005170:Factor X; D015951:Factor Xa; D005260:Female; D006493:Heparin; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D010375:Pedigree; D013924:Thrombophlebitis; D... | Acta haematologica | 1,984 | D000906:Antibodies; D058833:Antithrombin Proteins; D000991:Antithrombins; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; C039801:antithrombin III Trento; D005170:Factor X; D006493:Heparin; D015951:Factor Xa |
Phosphoric acid catalyzed diastereo- and enantioselective synthesis of substituted 1,3-diaminotetralins. | The reaction of anilines and phenylacetaldehydes in the presence of chiral phosphoric acid afforded optically active 1,2-trans, 2,3-cis 1,3-diaminotetralins in high yields with excellent diastereo- and enantioselectivities. The trans/cis product was readily isomerized to a trans/trans stereoisomer with no significant l... | 10.1021/ol500946w | 24,762,190 | D000079:Acetaldehyde; D002384:Catalysis; D015394:Molecular Structure; D009570:Nitriles; D010756:Phosphoric Acids; D013237:Stereoisomerism; D013764:Tetrahydronaphthalenes | Organic letters | 2,014 | D009570:Nitriles; D010756:Phosphoric Acids; D013764:Tetrahydronaphthalenes; C030242:phosphoric acid; D000079:Acetaldehyde; C013192:phenylacetaldehyde |
Field methods for rapidly characterizing paint waste during bridge rehabilitation. | For Department of Transportation (DOT) agencies, bridge rehabilitation involving paint removal results in waste that is often managed as hazardous. Hence, an approach that provides field characterization of the waste classification would be beneficial. In this study, an analysis of variables critical to the leaching pr... | 25,550,111 | D004784:Environmental Monitoring; D019216:Metals, Heavy; D008962:Models, Theoretical; D010150:Paint; D013052:Spectrometry, X-Ray Emission | Chemosphere | 2,015 | D019216:Metals, Heavy | |
Ocular Neural Heterotopia in a Moroccan Uromastyx (Uromastyx acanthinurus nigriventris). | A juvenile female Moroccan uromastyx (Uromastyx acanthinurus nigriventris) that died unexpectedly was necropsied. Necropsy examination revealed minimal intracoelomic fat, small numbers of intestinal nematodes and intraocular masses within the vitreous chamber of both eyes. One of the intraocular masses was focally cont... | 10.1016/j.jcpa.2019.09.006 | 31,690,407 | D000818:Animals; D002828:Choristoma; D005123:Eye; D005260:Female; D008116:Lizards; D009421:Nervous System Malformations; D054258:Neural Plate; D009900:Optic Nerve | Journal of comparative pathology | 2,019 | |
Winter cropping in Ficus tinctoria: an alternative strategy. | The many species of figs (Ficus, Moraceae) have evolved a variety of reproductive phenologies that ensure the survival of both the fig plants and their short-lived, species-specific, pollinating wasps. A phenological study of 28 male and 23 female plants of a dioecious hemiepiphytic fig, Ficus tinctoria, was conducted ... | 10.1038/srep16496 | 26,560,072 | D000818:Animals; D002681:China; D030681:Ficus; D054817:Pollination; D012098:Reproduction; D014863:Wasps | Scientific reports | 2,015 | |
Gastroschisis: early enteral feeds may improve outcome. | OBJECTIVE
Population-based retrospective review of gastroschisis from 1986 to 1996.
METHODS
This was a retrospective review of gastroschisis. Seventy cases were identified from the Birth Defects Registry of Western Australia (WA). Hospital medical records of live-born cases were reviewed.
RESULTS
The live-born inci... | 10.1046/j.1440-1754.2000.00552.x | 11,036,804 | D000328:Adult; D001315:Australia; D002391:Catchment Area, Health; D004750:Enteral Nutrition; D005260:Female; D020139:Gastroschisis; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D008423:Maternal Age; D011159:Population Surveillance; D012042:Re... | Journal of paediatrics and child health | 2,000 | |
Computed tomography angiography in the planning of transcatheter aortic valve replacement: a step-by-step approach. | Aortic valve stenosis is the most common acquired valvular heart disease. Transcatheter aortic valve implantation, also known as transcatheter aortic valve replacement (TAVR), is an important treatment option for symptomatic aortic stenosis in patients at any level of surgical risk. The role of computed tomography angi... | 10.1590/0100-3984.2021.0156 | 36,514,677 | Radiologia brasileira | 2,022 | ||
Temporal memory and content memory for actions: adult age differences in acquisition and retention. | Young adult and elderly adult subjects were tested under incidental memory conditions for recognition memory of content and temporal memory for the order of a series of actions performed in the laboratory. The tests were conducted both shortly after completion of the series and 24 hours later, with different sets of ac... | 10.1080/07340669008251542 | 2,090,466 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005260:Female; D006801:Humans; D007858:Learning; D008297:Male; D008568:Memory; D008875:Middle Aged; D009483:Neuropsychological Tests; D012153:Retention, Psychology; D013997:Time Factors | Experimental aging research | 1,990 | |
Purification of the active C5a receptor from human polymorphonuclear leukocytes as a receptor-Gi complex. | We have isolated, in an active state, the C5a receptor from human polymorphonuclear leukocytes. The purification was achieved in a single step using a C5a affinity column in which the C5a molecule was coupled to the resin through its N terminus. The purified receptor, like the crude solubilized molecule, exhibited a si... | 10.1073/pnas.88.3.971 | 1,899,485 | D002462:Cell Membrane; D002846:Chromatography, Affinity; D015936:Complement C5a; D019204:GTP-Binding Proteins; D016244:Guanosine 5'-O-(3-Thiotriphosphate); D006801:Humans; D007700:Kinetics; D008970:Molecular Weight; D009243:NAD; D009504:Neutrophils; D037342:Pertussis Toxin; D044087:Receptor, Anaphylatoxin C5a; D011951:... | Proceedings of the National Academy of Sciences of the United States of America | 1,991 | D044087:Receptor, Anaphylatoxin C5a; D011951:Receptors, Complement; D010566:Virulence Factors, Bordetella; D009243:NAD; D016244:Guanosine 5'-O-(3-Thiotriphosphate); D015936:Complement C5a; D037342:Pertussis Toxin; D019204:GTP-Binding Proteins |
Familial streptomycin ototoxicity in a South African family: a mitochondrial disorder. | The vestibular and ototoxic effects of the aminoglycoside antibiotics (streptomycin, gentamycin, kanamycin, tobramycin, neomycin) are well known; streptomycin, in particular, has been found to cause irreversible, profound, high frequency sensorineural deafness in hypersensitive persons. Aminoglycoside ototoxicity occur... | 10.1136/jmg.34.11.904 | 9,391,883 | D000900:Anti-Bacterial Agents; D003638:Deafness; D005260:Female; D006801:Humans; D008297:Male; D008928:Mitochondria; D010375:Pedigree; D013019:South Africa; D013307:Streptomycin | Journal of medical genetics | 1,997 | D000900:Anti-Bacterial Agents; D013307:Streptomycin |
Preemptive inotuzumab ozogamicin eradicated measurable residual disease in Ph-negative acute lymphoblastic leukemia relapsed post CD19 CART therapy. | There are no reports of application of inotuzumab ozogamicin (InO) for the treatment of MRD in r/r B-ALL. We firstly report the efficacy of InO for a patient experienced morphological relapse after HSCT and molecular relapse after CART therapy. | 10.1002/ccr3.8289 | 38,084,356 | Clinical case reports | 2,023 | ||
Protective role of NF-kappaB1 (p50) in experimental pneumococcal meningitis. | Nuclear factor-kappaB (NF-kappaB) is a critical regulator of many genes involved in the pathogenesis of bacterial meningitis. Recently, activation of NF-kappaB was shown to be a key event in the inflammatory host response and the development of intracranial complications during experimental pneumococcal meningitis. Sin... | 10.1016/j.ejphar.2004.07.081 | 15,364,010 | D000818:Animals; D001921:Brain; D002531:Cerebellum; D004195:Disease Models, Animal; D007375:Interleukin-1; D007958:Leukocyte Count; D008586:Meningitis, Pneumococcal; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D016328:NF-kappa B; D013296:Streptococcus pneumoniae; D051996:Transcription Factor RelA | European journal of pharmacology | 2,004 | D007375:Interleukin-1; D016328:NF-kappa B; D051996:Transcription Factor RelA |
Chest Computed Tomography Radiation Dose Optimization: Comparison of Automatic Exposure Control Strength Curves. | PURPOSE
The aim of the study was to compare radiation dose and image quality between the "average" and the "very strong" automatic exposure control (AEC) strength curves.
MATERIALS AND METHODS
Images reconstructed with filtered back-projection techniques and radiation dose data of unenhanced helical chest computed to... | 10.1097/RTI.0000000000000177 | 26,447,870 | D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed | Journal of thoracic imaging | 2,016 | |
Infertility caused by antispermatozoal antibodies in the male experience from an intermittent high dose cortisone regimen. | Seventeen infertile male patients with antispermatozoal antibodies in seminal plasma and/or serum were treated with methylprednisolone, 48-96 mg daily for one week every other month in synchrony with the partner's menstrual cycles. Three to six treatment courses were given. One patient with draw from further treatment ... | 10.1111/j.1439-0272.1988.tb01064.x | 3,177,902 | D000328:Adult; D001323:Autoantibodies; D003348:Cortisone; D006801:Humans; D007248:Infertility, Male; D008297:Male; D013094:Spermatozoa | Andrologia | 1,988 | D001323:Autoantibodies; D003348:Cortisone |
Dopaminergic activity in depressed smokers: a positron emission tomography study. | Tobacco dependence is highly prevalent in depressed patients. We assessed changes in [(11)C]-raclopride binding potential (BP) using positron emission tomography (PET) before and after the oral administration of d-amphetamine in healthy controls and unmedicated patients with current depression with and without current ... | 10.1002/syn.20646 | 19,360,907 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000661:Amphetamine; D001667:Binding, Competitive; D003863:Depression; D004298:Dopamine; D018492:Dopamine Antagonists; D018765:Dopamine Uptake Inhibitors; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875... | Synapse (New York, N.Y.) | 2,009 | D018492:Dopamine Antagonists; D018765:Dopamine Uptake Inhibitors; D020891:Raclopride; D000661:Amphetamine; D004298:Dopamine |
Patterns of Venous Thromboembolism Prophylaxis During Treatment of Acute Leukemia: Results of a North American Web-Based Survey. | BACKGROUND
Venous thromboembolism (VTE) occurs in 2% to 12% of patients with acute leukemia (AL) despite disease- and therapy-associated thrombocytopenia, and it can be associated with significant morbidity and mortality. Because of the few high-quality studies, there are no evidence-based guidelines for VTE prophylaxi... | 26,363,982 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002170:Canada; D005260:Female; D005343:Fibrinolytic Agents; D019538:Health Care Surveys; D006801:Humans; D015470:Leukemia, Myeloid, Acute; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians'; D054198:Precursor Cell Lymphoblastic Leukemia-Lym... | Clinical lymphoma, myeloma & leukemia | 2,015 | D005343:Fibrinolytic Agents | |
Reduction of venous complications of intravenous diazepam. | Nonsteroidal anti-inflammatory agents (NSAIAs), administered preoperatively and for three days postoperatively, were evaluated for reduction in the occurrence of venous complications following conscious sedation with intravenous diazepam. Patients receiving NSAIAs had significant reduction in overall incidence of posto... | 3,868,308 | D000766:Anesthesia, Dental; D000771:Anesthesia, Intravenous; D000893:Anti-Inflammatory Agents; D003975:Diazepam; D006801:Humans; D010689:Phlebitis; D011229:Preanesthetic Medication; D013924:Thrombophlebitis; D013927:Thrombosis | Anesthesia progress | 1,985 | D000893:Anti-Inflammatory Agents; D003975:Diazepam | |
Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF-10: applications for cancer gene therapy. | Oncolytic HSV-1 has been developed as a novel anticancer agent. According to the properties and functions of HSV-1 encoded proteins, several genes have been targeted for engineering of oncolytic HSV-1. As a result, a variety of strategies have been applied to the engineering of oncolytic HSV-1. Success in cancer therap... | 10.2174/156652308784746422 | 18,537,595 | D000818:Animals; D002986:Clinical Trials as Topic; D005260:Female; D017781:Genes, Immediate-Early; D005818:Genetic Engineering; D015316:Genetic Therapy; D018259:Herpesvirus 1, Human; D006801:Humans; D008297:Male; D051379:Mice; D009154:Mutation; D009369:Neoplasms; D050130:Oncolytic Virotherapy; D014760:Viral Fusion Prot... | Current gene therapy | 2,008 | D014760:Viral Fusion Proteins |
[Gene RAD31 is identical to gene MEC1 of yeast Saccharomyces cerevisiae]. | The earlier identified gene RAD31 was mapped on the right arm of chromosome II in the region of gene MEC1 localization. Epistatic analysis demonstrated that the rad31 mutation is an allele of the MEC1 gene, which allows further designation of the rad31 mutation as mec1-212. Mutation mec1-212, similar to deletion allele... | 21,786,666 | D000483:Alleles; D002172:Canavanine; D002874:Chromosome Mapping; D004843:Epistasis, Genetic; D018816:Genes, cdc; D006918:Hydroxyurea; D047908:Intracellular Signaling Peptides and Proteins; D016296:Mutagenesis; D017346:Protein Serine-Threonine Kinases; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae P... | Genetika | 2,011 | D047908:Intracellular Signaling Peptides and Proteins; D029701:Saccharomyces cerevisiae Proteins; D002172:Canavanine; C088937:MEC1 protein, S cerevisiae; D017346:Protein Serine-Threonine Kinases; D006918:Hydroxyurea | |
Training counterparts in cleft palate speech therapy in the less developed world: an extended report. | This paper describes the training of five counterparts in cleft palate speech therapy which took place in Sri Lanka. The context in which this training occurred is described. The original aims of the training, and criteria drawn up for the selection of the counterparts, are contrasted with the modifications required to... | 10.3109/13682829009011983 | 2,095,840 | D000488:Allied Health Personnel; D002972:Cleft Palate; D003906:Developing Countries; D006801:Humans; D013070:Speech Therapy; D013188:Sri Lanka; D013663:Teaching | The British journal of disorders of communication | 1,990 | |
The use of miniscrew implants for temporary skeletal anchorage in orthodontics: a comprehensive review. | Though not a novel therapeutic concept, the use of miniscrew implants to obtain absolute anchorage has recently become very popular in clinical orthodontic approaches. The mode of anchorage facilitated by these implant systems has a unique characteristic owing to their temporary use, which results in a transient, albei... | 10.1016/j.tripleo.2006.11.022 | 17,317,235 | D001863:Bone Screws; D003758:Dental Implantation, Endosseous; D020878:Device Removal; D004868:Equipment Failure; D006801:Humans; D008904:Miniaturization; D052280:Orthodontic Anchorage Procedures; D016382:Orthodontic Appliance Design | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics | 2,007 | |
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling. | Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR)-2 and VEGFR-3 have been implicated in angiogenic sprouting. Surprisingly, we found that endothelia... | 10.1038/ncb2331 | 21,909,098 | D000818:Animals; D000906:Antibodies; D045744:Cell Line, Tumor; D042783:Endothelial Cells; D051858:Forkhead Transcription Factors; D005786:Gene Expression Regulation; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D008264:Macrophages; D051379:Mice; D018345:Mice, Knockout; D009389:Neovascularization, Pat... | Nature cell biology | 2,011 | D000906:Antibodies; D051858:Forkhead Transcription Factors; D047428:Protein Kinase Inhibitors; D051880:Receptors, Notch; C467484:VEGFA protein, human; C467485:VEGFB protein, human; D042461:Vascular Endothelial Growth Factor A; D042561:Vascular Endothelial Growth Factor B; D042582:Vascular Endothelial Growth Factor C; D... |
[Personal experience with Osgood-Schlatter disease]. | The authors present a group of 49 patients treated over the period of ten years for the Osgood-Schlatter disease. Conservative treatment was employed in 5 patients and 44 patients were treated surgically by the excision of the loose fragment of apophysis. On the basis of the evaluation of the data the authors state tha... | 2,336,902 | D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010007:Osteochondritis | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca | 1,990 | ||
Assessment of light touch sensation in the hands of systemic sclerosis patients. | INTRODUCTION
Systemic sclerosis is a relatively rare connective tissue disorder characterized by severe and progressive fibrosis of the skin. Due to the current lack of available information on this subject, the aim of the present study was to assess light touch sensations in the hands of patients with systemic scleros... | 25,318,088 | D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006225:Hand; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012595:Scleroderma, Systemic; D012867:Skin; D020886:Somatosensory Disorders; D018709:Statistics, Nonparametric; D055698:Touch Percepti... | Clinics (Sao Paulo, Brazil) | 2,014 | ||
Evaluation of antimicrobial effects of commercial mouthwashes utilized in South Korea. | Streptococcus mutans is frequently associated with dental caries. Bacterial fermentation of food debris generates an acidic environment on the tooth surface, ultimately resulting in tooth deterioration. Therefore, various mouthwashes have been used to reduce and prevent Streptococcus mutans. The aim of this study was t... | 10.5483/bmbrep.2015.48.1.090 | 24,856,826 | D000890:Anti-Infective Agents; D018441:Biofilms; D008826:Microbial Sensitivity Tests; D009067:Mouthwashes; D056910:Republic of Korea; D013295:Streptococcus mutans | BMB reports | 2,015 | D000890:Anti-Infective Agents; D009067:Mouthwashes |
Phoenix dactylifera Protects against Doxorubicin-Induced Cardiotoxicity and Nephrotoxicity. | Doxorubicin (DOX) is an important anticancer drug used widely in the treatment of leukemia and lymphoma. The suitability of DOX is enhanced by its high therapeutic index, but its potential to cause cardiotoxicity and nephrotoxicity remains a prime concern in anticancer therapeutics. This study is designed to determine ... | 10.1155/2019/7395239 | 31,929,900 | Cardiology research and practice | 2,019 | ||
Perpetual role of brachytherapy in organ-sparing treatment for bladder cancer: a historical review. | Brachytherapy-based radiotherapy has been applied for decades in the curative treatment for solitary, ≤ 5 cm bladder tumors. This review provides a historical perspective of this organ sparing approach. A systematic search of the published literature between 1900 and 2019 was performed on the subject of bladder brachyt... | 10.5114/jcb.2020.101697 | 33,437,312 | Journal of contemporary brachytherapy | 2,020 | ||
Allele-specific RNA interference for neurological disease. | Suppressing the expression of toxic genes through RNAi holds great promise for the treatment of human disease. Allele-specific approaches have now been used to silence dominant toxic genes implicated in several neurological disorders. Here, we review strategies used to achieve allele-specific silencing in light of rece... | 10.1038/sj.gt.3302702 | 16,355,113 | D000483:Alleles; D000818:Animals; D005544:Forecasting; D005799:Genes, Dominant; D015316:Genetic Therapy; D006801:Humans; D035683:MicroRNAs; D009422:Nervous System Diseases; D034622:RNA Interference; D034741:RNA, Small Interfering | Gene therapy | 2,006 | D035683:MicroRNAs; D034741:RNA, Small Interfering |
Challenges and options for animal and public health services in the next two decades. | Trade in livestock and livestock products makes up approximately one sixth of global agriculture trade. This trade is demand driven, primarily by growing human populations, changing economies, and consumer preferences in developing countries. Different rates of population growth, economic growth, urbanisation, environm... | 16,796,064 | D000822:Animal Husbandry; D000827:Animal Welfare; D000818:Animals; D003132:Commerce; D004190:Disasters; D005544:Forecasting; D006801:Humans; D011157:Population Dynamics; D011158:Population Growth; D011203:Poverty; D011634:Public Health | Revue scientifique et technique (International Office of Epizootics) | 2,006 | ||
Comparing the reliability of responses to telephone-administered versus self-administered Web-based surveys in a case-control study of adult malignant brain cancer. | INTRODUCTION
To determine whether a Web-based survey was an acceptable method of data collection for a clinic-based case-control study of adult brain cancer, the authors compared the reliability of paired responses to a main and resurvey for participants completing surveys by telephone (n=74) or self-administered on th... | 10.1158/1055-9965.EPI-08-0304 | 18,843,005 | D000328:Adult; D001932:Brain Neoplasms; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D020407:Internet; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013689:Telepho... | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology | 2,008 | |
Study on biomethonization of waste water from jam industries. | Anaerobic digestion of wastewater from jam industries was studied in a continuous reactor with different organic loading rates (OLR) and the optimum organic loading rate was 6.5 kg COD/m(3)/day when it was operated with three days HRT. The biodegradability of wastewater in batch experiments was about 90%. The removal e... | 10.1016/j.biortech.2006.11.044 | 17,275,291 | D001421:Bacteria, Anaerobic; D001673:Biodegradation, Environmental; D019149:Bioreactors; D005232:Fatty Acids, Volatile; D005285:Fermentation; D005525:Food-Processing Industry; D006863:Hydrogen-Ion Concentration; D007220:Industrial Waste; D008697:Methane; D009584:Nitrogen; D010100:Oxygen; D013997:Time Factors; D014865:W... | Bioresource technology | 2,008 | D005232:Fatty Acids, Volatile; D007220:Industrial Waste; D014874:Water Pollutants, Chemical; D009584:Nitrogen; D008697:Methane; D010100:Oxygen |
Social and medical care of preschool children with epilepsy in Croatia: population-based survey. | BACKGROUND
Early detection of mental retardation and other epilepsy-associated impairments is essential for successful medical and social care of children with epilepsy; the corresponding information for children in Croatia has not yet been known.
AIMS OF THE STUDY
To obtain the basic information of epilepsy-associat... | 10.1016/j.ejpn.2008.12.003 | 19,196,528 | D000927:Anticonvulsants; D002648:Child; D002675:Child, Preschool; D018672:Community Health Planning; D017523:Croatia; D003695:Delivery of Health Care; D002658:Developmental Disabilities; D004827:Epilepsy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012944:Social Support | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society | 2,010 | D000927:Anticonvulsants |
Influence of substrate on corneal epithelial cell viability within ocular surface models. | Corneal tissue engineering has improved dramatically over recent years. It is now possible to apply these technological advancements to the development of superior in vitro ocular surface models to reduce animal testing. We aim to show the effect different substrates can have on the viability of expanded corneal epithe... | 10.1016/j.exer.2012.05.005 | 22,683,913 | D002452:Cell Count; D002460:Cell Line; D002470:Cell Survival; D003094:Collagen; D019573:Epithelium, Corneal; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D039663:Integrin beta4; D008565:Membrane Proteins; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D010750:Phosphoproteins; D... | Experimental eye research | 2,012 | D039663:Integrin beta4; D008565:Membrane Proteins; D010750:Phosphoproteins; D011076:Polycarboxylate Cement; C569042:TJP1 protein, human; D062826:Zonula Occludens-1 Protein; C005506:polycarbonate; D012967:Sodium Dodecyl Sulfate; D003094:Collagen |
Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts. | AIM
The objective of the present study was to determine the in vivo antitumor activity of elacytarabine, the 5'-elaidic acid ester of arabinofuranosyl cytidine, alone and in combination with bevacizumab, cetuximab and trastuzumab in Vascular endothelial growth factor (VEGF), Epidermal growth factor receptor (EGFR)- and... | 24,023,287 | D000818:Animals; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols; D000068258:Bevacizumab; D002289:Carcinoma, Non-Small-Cell Lung; D000068818:Cetuximab; D003561:Cytarabine; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D051379:Mice; D008807:Mice, ... | Anticancer research | 2,013 | D061067:Antibodies, Monoclonal, Humanized; D003561:Cytarabine; C047645:5'-oleoyl cytarabine; D000068258:Bevacizumab; D000068878:Trastuzumab; D000068818:Cetuximab | |
Surface area in the insula was associated with 28-month functional outcome in first-episode psychosis. | Many studies have tested the relationship between demographic, clinical, and psychobiological measurements and clinical outcomes in ultra-high risk for psychosis (UHR) and first-episode psychosis (FEP). However, no study has investigated the relationship between multi-modal measurements and long-term outcomes for >2 ye... | 10.1038/s41537-021-00186-9 | 34,845,247 | NPJ schizophrenia | 2,021 | ||
Putative Riemerella anatipestifer Outer Membrane Protein H Affects Virulence. | Riemerella anatipestifer causes serious contagious disease in ducks, geese, and other fowl. However, as a harmful pathogen causing significant economic losses in the poultry industry, R. anatipestifer is still poorly understood for its pathogenesis mechanisms. In a previous study, we developed an indirect ELISA method ... | 10.3389/fmicb.2021.708225 | 34,616,377 | Frontiers in microbiology | 2,021 | ||
Effects of early post-hatch feeding on the growth performance, hormone secretion, intestinal morphology, and intestinal microbiota structure in broilers. | This study aimed to investigate the effects of time access to post-hatch feeding on the growth performance, hormone secretion, intestinal morphology, and intestinal microbiota structure of broilers. A total of 900 broilers were randomly allocated to 3 treatment groups, with 6 replicates of 50 broilers each. The 3 treat... | 10.1016/j.psj.2022.102133 | 36,174,266 | D000818:Animals; D002645:Chickens; D000069196:Gastrointestinal Microbiome; D007419:Intestinal Secretions; D007422:Intestines; D006728:Hormones; D000821:Animal Feed; D004032:Diet | Poultry science | 2,022 | D006728:Hormones |
Improving diversity, inclusion, and representation in radiology and radiation oncology part 1: why these matter. | The ACR Commission for Women and General Diversity is committed to identifying barriers to a diverse physician workforce in radiology and radiation oncology (RRO), and to offering policy recommendations to overcome these barriers. In Part 1 of a 2-part position article from the commission, diversity as a concept and it... | 24,993,534 | D018864:Cultural Diversity; D008913:Minority Groups; D010820:Physicians; D011287:Prejudice; D018787:Radiation Oncology; D014481:United States; D000078329:Workforce | Journal of the American College of Radiology : JACR | 2,014 | ||
Characterization of an ATP diphosphohydrolase (EC 3.6.1.5) in synaptosomes from cerebral cortex of adult rats. | Data from the literature have demonstrated that synaptosomal preparations from various sources can hydrolyze externally added ATP. Various authors characterized this activity as an ecto-ATPase. In the present report, we demonstrate that synaptosomal preparations obtained from the cerebral cortex of rats show ATPase act... | 10.1007/BF00966661 | 1,838,406 | D000244:Adenosine Diphosphate; D000251:Adenosine Triphosphatases; D000255:Adenosine Triphosphate; D000818:Animals; D001081:Apyrase; D002540:Cerebral Cortex; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013379:Substrate Specificity; ... | Neurochemical research | 1,991 | D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D001081:Apyrase |
[School counselors: from the prevention of drug abuse to a larger role]. | Since 1977, a programme has been launched in the Canton of Vaud (pop. 530,000), Switzerland, for the training and use of teachers as mediators in the school setting at various levels, to help tackling problems related to the use of drugs and other risk situations. They follow and in service training (14 afternoons) and... | 10.1007/BF02083163 | 4,036,349 | D000293:Adolescent; D000328:Adult; D002648:Child; D003376:Counseling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012574:Schools; D019966:Substance-Related Disorders; D013557:Switzerland | Sozial- und Praventivmedizin | 1,985 | |
Elevated levels of nitrate in rheumatoid arthritis. | Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate ... | 10.1007/s002960100105 | 11,411,960 | D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid; D015415:Biomarkers; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide; D011336:Probability; D011379:Prognosis; D012016:Reference Values; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index | Rheumatology international | 2,001 | D015415:Biomarkers; D009569:Nitric Oxide |
Simultaneous Determination of 2- and 3-MCPD Esters in Infant Formula Milk Powder by Solid-Phase Extraction and GC-MS Analysis. | The objective of this study was to establish a method for detecting fatty acid esters of chloropropanols [including 2-monochloropropane-1,3-diol (2-MCPD) ester and 3-monochloropropane-1,2-diol (3-MCPD) ester] in infant milk powder using isotope dilution and GC-MS. The fat fraction in infant milk powder samples was extr... | 10.5740/jaoacint.15-0310 | 27,076,396 | Journal of AOAC International | 2,016 | ||
Endovascular procedures under near-real-time magnetic resonance imaging guidance: an experimental feasibility study. | PURPOSE
The purpose of this study was to assess the feasibility of insertion of endovascular stents and the precision of an open-field interventional magnetic resonance imaging (iMRI) system in an in vivo model.
METHODS
A feasibility study was undertaken at a university-affiliated hospital. Three male piglets with an... | 10.1067/mva.2000.109208 | 11,054,233 | D000818:Animals; D002406:Catheterization, Peripheral; D005240:Feasibility Studies; D007083:Iliac Artery; D018810:Magnetic Resonance Angiography; D008297:Male; D023421:Models, Animal; D012680:Sensitivity and Specificity; D015607:Stents; D013552:Swine | Journal of vascular surgery | 2,000 | |
Antifertility effect of chronically administered Malviscus conzattii flower extract on fertility of male rats. | Quantitative evaluation of different varieties of germ cells at stage VII of the cycle, namely type A spermatogonia, pre-leptotene spermatocytes, mid-pachytene spermatocytes, step 7 and step 19 spermatids, along with radio-immunoassay of serum gonadotrophins (LH and FSH), testosterone and testicular testosterone were p... | 10.1016/0010-7824(91)90146-7 | 1,903,686 | D000818:Animals; D002453:Cell Cycle; D005298:Fertility; D005640:Follicle Stimulating Hormone; D007986:Luteinizing Hormone; D008297:Male; D010936:Plant Extracts; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D012671:Seminiferous Tubules; D013076:Sperm Count; D013081:Sperm Motility; D013087:Sperma... | Contraception | 1,991 | D010936:Plant Extracts; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone |
Chinese Sign Language Recognition Based on an Optimized Tree-Structure Framework. | Chinese Sign Language (CSL) subword recognition based on surface electromyography (sEMG), accelerometer (ACC), and gyroscope (GYRO) sensors was explored in this paper. In order to fuse effectively the information of these three kinds of sensors, the classification abilities of sEMG, ACC, GYRO, and their combinations in... | 10.1109/JBHI.2016.2560907 | 27,164,613 | D061725:Accelerometry; D000328:Adult; D000465:Algorithms; D002681:China; D004576:Electromyography; D004867:Equipment Design; D005868:Gestures; D006801:Humans; D008297:Male; D009068:Movement; D010363:Pattern Recognition, Automated; D012813:Sign Language; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult | IEEE journal of biomedical and health informatics | 2,017 | |
[Imaging methods]. | A number of abnormalities of the shoulder joint can cause pain or dysfunction. Imaging of this complex joint is demanding. Standard radiographs are considered to represent the basis of all imaging. For more detailed diagnoses, especially concerning soft tissue, more advanced imaging methods are required. Standard arthr... | 9,562,818 | D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006801:Humans; D007592:Joint Diseases; D012680:Sensitivity and Specificity; D012782:Shoulder; D000070599:Shoulder Injuries; D012785:Shoulder Joint | Therapeutische Umschau. Revue therapeutique | 1,998 | ||
[Young suicide patients and emotional climate in family]. | The examination deals with the emotional climate in the family and looks into the reasons for disturbances thereof, with special emphasis on the significant role of alcoholism and the relations between the parents. Reference is made to the frequency of disturbed familial relations in suicide attempts among young people... | 847,044 | D000293:Adolescent; D000437:Alcoholism; D002648:Child; D005191:Family Characteristics; D006801:Humans; D010287:Parent-Child Relations; D013406:Suicide, Attempted | Psychiatrie, Neurologie, und medizinische Psychologie | 1,977 | ||
Catalytic Self-Assembly of Quantum-Dot-Based MicroRNA Nanosensor Directed by Toehold-Mediated Strand Displacement Cascade. | Semiconductor quantum dots (QDs) are highly attractive nanomaterials with wide biomedical applications owing to their unique photophysical properties. However, the adaptation of the nonenzymatic QD nanosensor assembly to sense low-abundance targets remains a great challenge. Herein, taking advantage of the dynamic DNA ... | 10.1021/acs.nanolett.9b02544 | 31,460,766 | D045744:Cell Line, Tumor; D000074166:Circulating MicroRNA; D031541:Fluorescence Resonance Energy Transfer; D006801:Humans; D008856:Microscopy, Fluorescence; D045663:Quantum Dots | Nano letters | 2,019 | D000074166:Circulating MicroRNA |
Isolation, cloning and expression of CCA1 gene in transgenic progeny plants of Japonica rice exhibiting altered morphological traits. | Circadian clock genes holds tremendous potential for breeding crops better adapted to environmental fluctuations inherent to climate change. Endogenous TOC1 promoter and CCA1 gene from rice were isolated, cloned and mobilized into pCAMBIA1300 vectors and RNAi constructs A, B and C. Embryogenic calli of varying ages der... | 10.1371/journal.pone.0220140 | 31,381,594 | D060054:Agrobacterium; D003001:Cloning, Molecular; D018506:Gene Expression Regulation, Plant; D012275:Oryza; D010940:Plant Proteins; D030821:Plants, Genetically Modified; D011401:Promoter Regions, Genetic; D014157:Transcription Factors; D014170:Transformation, Genetic | PloS one | 2,019 | D010940:Plant Proteins; D014157:Transcription Factors |
Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities. | Stilbenes and benzofuran neolignans are important groups of plant phenolics therefore they play a significant role in plants and human health. The objective of this study was to investigate the structure-activity relationships of naturally occurring stilbene and benzofuran neolignan derivatives as acetylcholinesterase ... | 10.1016/j.bmcl.2019.07.026 | 31,350,127 | D000110:Acetylcholinesterase; D000818:Animals; D000893:Anti-Inflammatory Agents; D001572:Benzofurans; D002470:Cell Survival; D002800:Cholinesterase Inhibitors; D007371:Interferon-gamma; D007536:Isomerism; D017705:Lignans; D008070:Lipopolysaccharides; D008264:Macrophages; D051379:Mice; D018696:Neuroprotective Agents; D0... | Bioorganic & medicinal chemistry letters | 2,019 | D000893:Anti-Inflammatory Agents; D001572:Benzofurans; D002800:Cholinesterase Inhibitors; D017705:Lignans; D008070:Lipopolysaccharides; D018696:Neuroprotective Agents; D013267:Stilbenes; D009569:Nitric Oxide; D007371:Interferon-gamma; D000110:Acetylcholinesterase |
Subclinical effects of adapalene-benzoyl peroxide: a prospective in vivo imaging study on acne micromorphology and transfollicular delivery. | BACKGROUND
Adapalene-benzoyl peroxide (A-BPO) is a first-line topical treatment for acne vulgaris. In vivo reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) detect micromorphological changes over time and visualize transfollicular delivery.
OBJECTIVES
To visualize temporal, subclinical effe... | 10.1111/jdv.17140 | 33,508,886 | D000152:Acne Vulgaris; D000068816:Adapalene; D001585:Benzoyl Peroxide; D003879:Dermatologic Agents; D004338:Drug Combinations; D005782:Gels; D006801:Humans; D011446:Prospective Studies; D016896:Treatment Outcome | Journal of the European Academy of Dermatology and Venereology : JEADV | 2,021 | D003879:Dermatologic Agents; D004338:Drug Combinations; D005782:Gels; D000068816:Adapalene; D001585:Benzoyl Peroxide |
Acute thrombosis of the inferior vena cava and hepatic veins in patients with Budd-Chiari syndrome: CT demonstration. | We reviewed the CT findings in 17 patients with angiographically proved Budd-Chiari syndrome to determine the ability of CT to show acute thrombosis of the inferior vena cava (IVC) and hepatic veins. In eight patients with membranes (web or band) in the IVC, no thrombus was detected with CT or angiography. In the other... | 10.2214/ajr.153.5.987 | 2,801,448 | D000208:Acute Disease; D000328:Adult; D000368:Aged; D006502:Budd-Chiari Syndrome; D005069:Evaluation Studies as Topic; D005260:Female; D006503:Hepatic Veins; D006801:Humans; D008297:Male; D008875:Middle Aged; D013927:Thrombosis; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior | AJR. American journal of roentgenology | 1,989 | |
A novel system for correcting large-scale chromosomal aberrations: ring chromosome correction via reprogramming into induced pluripotent stem cell (iPSC). | Approximately 1 in 500 newborns are born with chromosomal abnormalities that include trisomies, translocations, large deletions, and duplications. There is currently no therapeutic approach for correcting such chromosomal aberrations in vivo or in vitro. When we attempted to produce induced pluripotent stem cell (iPSC)... | 10.1007/s00412-016-0621-6 | 27,882,407 | D002478:Cells, Cultured; D065150:Cellular Reprogramming; D005347:Fibroblasts; D015316:Genetic Therapy; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D012303:Ring Chromosomes; D024182:Uniparental Disomy | Chromosoma | 2,017 | |
Hematopoietic features and apoptosis in the bone marrow of severe Plasmodium falciparum-infected patients: preliminary study. | The mechanism of anemia in severe falciparum malaria is still not completely understood. The purpose of this study was to determine whether apoptosis in the erythroid lineage causes anemia in falciparum malaria. Bone marrow aspirated from 8 severe falciparum malaria patients, 3 normal volunteers and 5 retrospective nor... | 16,124,415 | D000740:Anemia; D000818:Animals; D017209:Apoptosis; D001854:Bone Marrow Cells; D016022:Case-Control Studies; D053938:DNA Fragmentation; D004587:Electrophoresis, Agar Gel; D041905:Erythroid Cells; D006410:Hematopoiesis; D006801:Humans; D016778:Malaria, Falciparum; D023461:Myeloid Progenitor Cells; D010718:Phosphatidylse... | The Southeast Asian journal of tropical medicine and public health | 2,005 | D010718:Phosphatidylserines | |
Regulation of expression of type I signal peptidases in Listeria monocytogenes. | The role of type I signal peptidases (SPases I) is to remove the signal peptides of preproteins exported by the general secretory pathway. The genome of Listeria monocytogenes contains a locus encoding three contiguous SPases I (denoted SipX, SipY and SipZ). The authors recently showed that SipX and SipZ perform distin... | 10.1099/mic.0.28066-0 | 16,272,398 | D001426:Bacterial Proteins; D018938:Caco-2 Cells; D003470:Culture Media; D049071:Endopeptidase Clp; D005260:Female; D015964:Gene Expression Regulation, Bacterial; D006360:Heat-Shock Proteins; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008089:Listeria monocytogenes; D008565:Membrane Proteins; D010454:Peptide T... | Microbiology (Reading, England) | 2,005 | D001426:Bacterial Proteins; C087481:ClpC protein, Bacteria; D003470:Culture Media; D006360:Heat-Shock Proteins; D008565:Membrane Proteins; D010454:Peptide Termination Factors; D012697:Serine Endopeptidases; C026515:type I signal peptidase; D049071:Endopeptidase Clp |
In vivo and in vitro invasiveness of human lung carcinoma cell lines. | Eight cell lines derived from human non-small cell lung carcinomas were used to compare their in vivo invasiveness, in vitro chemoinvasive abilities and type IV collagenase activity. For the evaluation of the in vivo invasive potential, the tumor cells were seeded into deepithelialized rat tracheas and transplanted sub... | 1,655,672 | D000818:Animals; D002289:Carcinoma, Non-Small-Cell Lung; D002460:Cell Line; D002633:Chemotaxis; D004792:Enzyme Precursors; D006801:Humans; D008175:Lung Neoplasms; D020780:Matrix Metalloproteinase 9; D051379:Mice; D008807:Mice, Inbred BALB C; D003012:Microbial Collagenase; D009361:Neoplasm Invasiveness; D009368:Neoplasm... | Invasion & metastasis | 1,991 | D004792:Enzyme Precursors; D003012:Microbial Collagenase; D020780:Matrix Metalloproteinase 9 | |
Carolina rinse attenuates postischemic microvascular injury in rat small bowel isografts. | BACKGROUND
Apart from rejection-related events, the manifestation of ischemia/reperfusion (I/R) injury remains a major problem, hampering success in human small bowel transplantation (SBTx). Therefore the aim of this study was to determine the potential of Carolina rinse (CR) to attenuate microvascular reperfusion inju... | 9,481,404 | D000818:Animals; D001808:Blood Vessels; D002450:Cell Communication; D004730:Endothelium, Vascular; D006439:Hemodynamics; D007413:Intestinal Mucosa; D007421:Intestine, Small; D007511:Ischemia; D007962:Leukocytes; D008297:Male; D008833:Microcirculation; D009130:Muscle, Smooth; D051381:Rats; D011917:Rats, Inbred Lew; D012... | Surgery | 1,998 | C070887:Carolina rinse solution; D012996:Solutions | |
Anthropometric fractionation of body mass: Matiegka revisited. | In a group of 699 Belgian nursing professionals, we estimated body composition using the four-component anthropometric model, relying on the equations originally formulated by Matiegka in 1921 and later revised by Drinkwater and colleagues. We estimated muscle mass using the more recent formula proposed by Martin and c... | 10.1080/026404102320219428 | 12,200,923 | D000328:Adult; D000886:Anthropometry; D001530:Belgium; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity | Journal of sports sciences | 2,002 | |
Melatonin attenuates antipsychotic metabolic effects: an eight-week randomized, double-blind, parallel-group, placebo-controlled clinical trial. | OBJECTIVE
Second-generation antipsychotics (SGAs) are among the first-line treatments for bipolar disorder and schizophrenia, but have a tendency to generate metabolic disturbances. These features resemble a metabolic syndrome for which a central autonomic imbalance has been proposed that may originate from the hypotha... | 10.1111/bdi.12196 | 24,636,483 | D000328:Adult; D000704:Analysis of Variance; D000886:Anthropometry; D000975:Antioxidants; D001714:Bipolar Disorder; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008550:Melatonin; D001523:Mental Disorders; D008659:Metabolic Diseases; D012189:Retrospective Studies... | Bipolar disorders | 2,014 | D000975:Antioxidants; D008550:Melatonin |
Comparison of apical extrusion of intracanal bacteria by various glide-path establishing systems: an in vitro study. | OBJECTIVES
This study compared the amount of apically extruded bacteria during the glide-path preparation by using multi-file and single-file glide-path establishing nickel-titanium (NiTi) rotary systems.
MATERIALS AND METHODS
Sixty mandibular first molar teeth were used to prepare the test apparatus. They were decor... | 10.5395/rde.2017.42.4.316 | 29,142,880 | Restorative dentistry & endodontics | 2,017 | ||
Post-Discharge Events Occurring after Dental Treatment under Deep Sedation in Pediatric Patients. | PURPOSE
Deep sedation is often required in dentistry for treating children with uncooperative behavior. We assessed immediate post-sedation events during the first 24 hours after dental treatment under deep sedation in children, and examined correlations to a number of variables.
STUDY DESIGN
Information was collecte... | 10.17796/1053-4628-41.3.232 | 28,422,597 | D000293:Adolescent; D000766:Anesthesia, Dental; D002648:Child; D002675:Child, Preschool; D054810:Deep Sedation; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007223:Infant; D008297:Male; D012494:Sampling Studies | The Journal of clinical pediatric dentistry | 2,017 | D006993:Hypnotics and Sedatives |
The role of microencapsulation in maintaining biological activity of royal jelly: comparison with biological activity and bioaccessibility of microencapsulated, fresh and lyophilized forms during storage. | BACKGROUND
Royal jelly (RJ) is a unique beehive product and has been recommended for human health since ancient times because of its antioxidant, antimicrobial, antiproliferative, neuroprotective, anti-lipidemic and anti-aging features. However, the biggest obstacle in the use of RJ is the need for cold storage and the... | 10.1002/jsfa.11905 | 35,355,271 | D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000975:Antioxidants; D005227:Fatty Acids; D006801:Humans | Journal of the science of food and agriculture | 2,022 | D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000975:Antioxidants; D005227:Fatty Acids; C058787:royal jelly |
Effects of urinary bladder distension on activity of T3-T4 spinal neurons receiving cardiac and somatic noxious inputs in rats. | The aims of this study were to examine effects of urinary bladder distension (UBD) on T(3)-T(4) spinal neurons receiving cardiac and somatic noxious inputs and to determine the pathway involved in transmitting urinary bladder inputs to thoracic spinal segments. Extracellular potentials of single T(3)-T(4) neurons were ... | 10.1016/s0006-8993(03)02362-x | 12,706,237 | D000200:Action Potentials; D000241:Adenosine; D000344:Afferent Pathways; D000818:Animals; D001920:Bradykinin; D015232:Dinoprostone; D004338:Drug Combinations; D004594:Electrophysiology; D006632:Histamine; D008297:Male; D009433:Neural Inhibition; D009475:Neurons, Afferent; D010120:Oxytocics; D010812:Physical Stimulation... | Brain research | 2,003 | D004338:Drug Combinations; D010120:Oxytocics; D012701:Serotonin; D006632:Histamine; D000241:Adenosine; D015232:Dinoprostone; D001920:Bradykinin |
Natural history of early, localized prostate cancer. | CONTEXT
Among men with early prostate cancer, the natural history without initial therapy determines the potential for survival benefit following radical local treatment. However, little is known about disease progression and mortality beyond 10 to 15 years of watchful waiting.
OBJECTIVE
To examine the long-term natu... | 10.1001/jama.291.22.2713 | 15,187,052 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010641:Phenotype; D016012:Poisson Distribution; D011471:Prostatic Neoplasms; D016019:Survival Analysis | JAMA | 2,004 | |
Linking denitrification and infiltration rates during managed groundwater recharge. | We quantify relations between rates of in situ denitrification and saturated infiltration through shallow, sandy soils during managed groundwater recharge. We used thermal methods to determine time series of point-specific flow rates, and chemical and isotopic methods to assess denitrification progress. Zero order deni... | 10.1021/es2023626 | 21,992,590 | D058440:Denitrification; D005374:Filtration; D060587:Groundwater; D009566:Nitrates; D012987:Soil | Environmental science & technology | 2,011 | D009566:Nitrates; D012987:Soil |
Comparative evaluation of acute respiratory distress syndrome in patients with and without H1N1 infection at a tertiary care referral center. | H1N1 subtype of influenza A virus has clinical presentation ranging from mild flu like illness to severe lung injury and acute respiratory distress syndrome (ARDS). The aim of our study was to compare the demographic characteristics, clinical presentation, and mortality of critically ill patients with (H1N1+) and witho... | 10.4103/0019-5049.76602 | 21,431,053 | Indian journal of anaesthesia | 2,011 | ||
Sleep Complaints Among Adults With Major Depressive Episode Are Associated With Increased Risk of Incident Psychiatric Disorders: Results From a Population-Based 3-Year Prospective Study. | Sleep alterations have been suggested as a cause and consequence of psychiatric disorders. In this context, we evaluated the incidence of psychiatric disorders following sleep complaints in adults with major depressive episode (MDE).
In a large, nationally representative 3-year prospective survey, the National Epide... | 36,541,815 | D006801:Humans; D000328:Adult; D003865:Depressive Disorder, Major; D011446:Prospective Studies; D002189:Marijuana Abuse; D019966:Substance-Related Disorders; D006970:Disorders of Excessive Somnolence; D007319:Sleep Initiation and Maintenance Disorders; D014029:Tobacco Use Disorder; D012890:Sleep; D015897:Comorbidity | The Journal of clinical psychiatry | 2,022 | ||
Acute optic neuritis: What are the clues to the aetiological diagnosis in real life? | BACKGROUND
Previous cross-sectional studies have reported distinct clinical and radiological features among the different acute optic neuritis (ON) aetiologies. Nevertheless, these reports often included the same number of patients in each group, not taking into account the disparity in frequencies of ON aetiologies in... | 10.1016/j.msard.2023.104764 | 37,270,881 | D006801:Humans; D011446:Prospective Studies; D009902:Optic Neuritis; D009900:Optic Nerve; D063308:Myelin-Oligodendrocyte Glycoprotein; D009103:Multiple Sclerosis; D041623:Tomography, Optical Coherence; D014786:Vision Disorders | Multiple sclerosis and related disorders | 2,023 | D063308:Myelin-Oligodendrocyte Glycoprotein |
The yeast YKL741 gene situated on the left arm of chromosome XI codes for a homologue of the human ALD protein. | The yeast gene YKL741 is situated on the left arm of chromosome XI, 12 kb closer to the centromere with respect to the previously localized PAS1 gene. The new yeast gene codes for a homologue of the human ALD protein (ALD: adrenoleukodystrophy). The similarity between the YKL741 protein and the ALD protein is very high... | 10.1002/yea.320100512 | 7,941,751 | D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters; D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal; D016681:Genome, Fungal; D006801:Humans; D008565:Membrane Proteins; D008969:Molecular Sequence Data; ... | Yeast (Chichester, England) | 1,994 | C115572:ABCD1 protein, human; D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters; D008565:Membrane Proteins |
[Guying denture systems. Part 1. Tooth splinting]. | One of the elements of gyuing dentures suggested by the author is described in detail. It serves for redistribution of masticatory loading between natural teeth and can be used alone (for tooth splinting) and in combination with other elements of the proposed denture system (for orthodontic treatment of partial defects... | 12,772,559 | D003779:Denture Design; D003829:Denture, Partial; D006801:Humans; D010510:Periodontal Diseases; D010516:Periodontal Splints; D015203:Reproducibility of Results | Stomatologiia | 2,003 | ||
Traumatic hip dislocation in athletes. | Sports injuries are increasingly prevalent. Dislocations of the hip are rare; however, they are seen in high-velocity sports such as football and rugby. The injuries may be described as anterior or posterior, and classified according to severity of injury. It is critical to the sports medicine practitioner to promptly ... | 10.1249/00149619-200212000-00007 | 12,831,682 | D001265:Athletic Injuries; D003952:Diagnostic Imaging; D004638:Emergency Treatment; D006617:Hip Dislocation; D006621:Hip Joint; D006801:Humans; D010146:Pain; D059408:Pain Management | Current sports medicine reports | 2,002 |
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