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Characteristics and outcomes of emergency patients with self-inflicted injuries: a report from ambulance records in Osaka City, Japan. | BACKGROUND
Few studies have evaluated the actual situations of emergency patients with self-inflicted injuries treated by emergency-medical-service (EMS) personnel.
METHODS
This study retrospectively reviewed population-based ambulance records in Osaka City, Japan, between January 2010 and December 2012, and enrolled... | 10.1186/s13049-016-0261-0 | 27,170,115 | D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000552:Ambulances; D002648:Child; D004632:Emergency Medical Services; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D012189:Retrospective Studies; D012... | Scandinavian journal of trauma, resuscitation and emergency medicine | 2,016 | |
Morphologically homogeneous, pH-responsive gold nanoparticles for non-invasive imaging of HeLa cancer. | Gold nanoparticles (AuNPs) have been widely used as nanocarriers in drug delivery to improve the efficiency of chemotherapy treatment and enhance early disease detection. The advantages of AuNPs include their excellent biocompatibility, easy modification and functionalization, facile synthesis, low toxicity, and contro... | 10.1016/j.nano.2021.102394 | 33,857,687 | D000818:Animals; D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin; D005260:Female; D006046:Gold; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles; D051379:Mice; D049268:Positron-Emission Tomography; D011869:Radioligand Assay; D002583:Uterine Cervical Neoplasms;... | Nanomedicine : nanotechnology, biology, and medicine | 2,021 | D000903:Antibiotics, Antineoplastic; D006046:Gold; D004317:Doxorubicin |
The methylation of mercuric chloride by human intestinal bacteria. | Most strains of staphylococci, streptococci, yeasts and E. coli isolated from human faeces, could synthesize methylmercury compounds. In contrast, few strains of obligate anaerobes could do so. Up to 6 ng methylmercury/ml were formed in 44 h from 2 mug mercuric chloride. | 10.1007/BF02326961 | 1,100,426 | D000191:Actinomycetaceae; D000818:Animals; D001419:Bacteria; D001439:Bacteroides; D002432:Cecum; D002712:Chlorides; D004926:Escherichia coli; D006801:Humans; D007422:Intestines; D007778:Lactobacillus; D008628:Mercury; D008767:Methylmercury Compounds; D051381:Rats; D013210:Staphylococcus; D013291:Streptococcus; D015003:... | Experientia | 1,975 | D002712:Chlorides; D008767:Methylmercury Compounds; D008628:Mercury |
Impact of dose distribution on rotational setup errors in radiotherapy for prostate cancer. | This study aimed to assess the impact of rotational setup errors on the target volume's dose distribution during radiotherapy for prostate cancer. A 6D robotic couch was used to describe the rotational setup error, and the dosage change in the target volume was analyzed using the planning evaluation factors. Treatment ... | 10.1016/j.meddos.2023.03.007 | 37,085,402 | Medical dosimetry : official journal of the American Association of Medical Dosimetrists | 2,023 | ||
Clusters, superclusters, and large-scale structure: a consistent picture. | Observations of the large-scale structure in the universe using different tracers and techniques, including the spatial distribution of galaxies, clusters of galaxies, narrow pencil-beam surveys, and quasars, appear to be yielding a consistent picture of the universal structure. A network of large-scale superclusters w... | 10.1073/pnas.90.11.4848 | 11,607,398 | Proceedings of the National Academy of Sciences of the United States of America | 1,993 | ||
Negative pressure ventilation in pediatric critical care setting. | Invasive ventilation is associated with both pulmonary and non-pulmonary complications. There has been a renewed interest in the use of negative pressure ventilation (NPV) for various medical conditions to minimise the complications associated with positive pressure ventilation. The routine use of NPV in an ICU setting... | 10.1007/s12098-007-0082-2 | 17,526,961 | D001988:Bronchiolitis; D002648:Child; D006801:Humans; D007362:Intensive Care Units; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency; D015300:Ventilator Weaning; D015919:Ventilators, Negative-Pressure | Indian journal of pediatrics | 2,007 | |
Bariatric surgery in patients with type 1 diabetes: special considerations are warranted. | OBJECTIVE
We examined short and long-term outcomes of bariatric surgery in patients with obesity and type 1 diabetes mellitus (T1DM).
METHODS
We reviewed the records of all adults insured by Maccabi Healthcare Services during 2010 -2015, with body mass index (BMI) ⩾30 kg/m2 and T1DM; and compared weight reduction and... | 10.1177/2042018818822207 | 30,728,940 | Therapeutic advances in endocrinology and metabolism | 2,019 | ||
Genome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm. | We announce here the complete genome sequence of Paracoccus contaminans LMG 29738T, which we recently isolated from a contaminated water microcosm. The genome consists of a 2.94-Mb chromosome and a 94-kb plasmid. To our knowledge, we provide the first DNA methylation analysis of a Paracoccus species. | 10.1128/genomeA.00487-17 | 28,596,405 | Genome announcements | 2,017 | ||
Grey water treatment in a series anaerobic--aerobic system for irrigation. | This study aims at treatment of grey water for irrigation, focusing on a treatment technology that is robust, simple to operate and with minimum energy consumption. The result is an optimized system consisting of an anaerobic unit operated in upflow mode, with a 1 day operational cycle, a constant effluent flow rate an... | 10.1016/j.biortech.2009.07.056 | 19,699,088 | D000383:Agriculture; D001420:Bacteria, Aerobic; D001421:Bacteria, Anaerobic; D019149:Bioreactors; D014867:Water; D014874:Water Pollutants, Chemical; D018508:Water Purification; D014881:Water Supply | Bioresource technology | 2,010 | D014874:Water Pollutants, Chemical; D014867:Water |
Preparation, characterization and antioxidant activity of astaxanthin esters with different molecular structures. | BACKGROUND
Astaxanthin (Asta) is widely used in the nutraceutical and food industry because of its strong antioxidant properties. However, natural Asta mainly exists in the esterified form with various fatty acid chains, making it difficult to understand the particular molecular structure of astaxanthin esters (Asta-Es... | 10.1002/jsfa.10887 | 33,063,347 | D000975:Antioxidants; D004952:Esters; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D053719:Tandem Mass Spectrometry; D024341:Xanthophylls | Journal of the science of food and agriculture | 2,021 | D000975:Antioxidants; D004952:Esters; D024341:Xanthophylls; C005948:astaxanthine |
Gross and histologic characteristics of laparoscopic injuries with four different energy sources. | OBJECTIVE
To compare the gross and histologic effects of bipolar and monopolar cautery, ultrasonic scalpel, and CO(2) laser on porcine ureter, bladder, and rectum.
DESIGN
Experimental prospective study.
SETTING
Cleveland Clinic Foundation Animal Research Laboratory, Cleveland, Ohio.
ANIMAL(S)
Nonpregnant adult fe... | 10.1016/s0015-0282(00)01785-4 | 11,287,039 | D000818:Animals; D002245:Carbon Dioxide; D005260:Female; D006358:Hot Temperature; D007413:Intestinal Mucosa; D010535:Laparoscopy; D007834:Lasers; D010529:Peritoneal Cavity; D012007:Rectum; D013552:Swine; D014465:Ultrasonics; D014513:Ureter; D001743:Urinary Bladder | Fertility and sterility | 2,001 | D002245:Carbon Dioxide |
[Selectivity of the reverse transcriptase inhibitors toward types 1 and 2 of human immunodeficiency virus (HIV)]. | Two novel series of acyclonucleosides active as nonnucleoside reverse transcriptase inhibitors (NNRTI) against the human immunodeficiency virus (HIV) have been synthesized. Structural modifications, inverting the selectivity of classical NNRTI, considerably more active against HIV-1 than HIV-2, are reported. In these s... | 12,378,149 | D002478:Cells, Cultured; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D009705:Nucleosides; D018894:Reverse Transcriptase Inhibitors; D013329:Structure-Activity Relationship | Annales pharmaceutiques francaises | 2,002 | D009705:Nucleosides; D018894:Reverse Transcriptase Inhibitors | |
cDNA cloning of the chicken branched-chain alpha-keto acid dehydrogenase complex. Chicken-specific residues of the acyltransferase affect the overall activity and the interaction with the dehydrogenase. | Branched-chain alpha-keto acid dehydrogenase complex is a macromolecule comprising three catalytic components: a dehydrogenase (E1) with alpha(2)beta(2) structure, an acyltransferase (E2) and a dihydrolipoamide dehydrogenase (E3). In the mammalian complex, the E2 component with 24 identical subunits forms a structural ... | 10.1046/j.1432-1327.2001.01925.x | 11,168,412 | D042942:3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); D000217:Acyltransferases; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002499:Centrifugation, Density Gradient; D002645:Chickens; D003001:Cloning, Molecular; D017124:Conserved Sequence; D018076:DNA, Complementary; D00805... | European journal of biochemistry | 2,001 | D018076:DNA, Complementary; D009097:Multienzyme Complexes; D015345:Oligonucleotide Probes; D010455:Peptides; D007658:Ketone Oxidoreductases; D042942:3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); D008058:Dihydrolipoamide Dehydrogenase; D000217:Acyltransferases |
Intra-abdominal abscess in the course of intragastric migration of an adjustable gastric band: a potentially life-threatening complication. | Intragastric band migration is a potential complication of adjustable gastric banding. A 39-year-old morbidly obese female underwent laparoscopic adjustable gastric banding. After uneventful postoperative follow-up of 4 years, she had slow, steady failure of the restrictive effect, associated with regain of weight. Int... | 10.1381/096089206775222041 | 16,417,767 | D018784:Abdominal Abscess; D000328:Adult; D020878:Device Removal; D013505:Digestive System Surgical Procedures; D005260:Female; D005548:Foreign-Body Migration; D015390:Gastric Bypass; D015391:Gastroplasty; D006801:Humans; D010535:Laparoscopy; D019919:Prosthesis Implantation; D016459:Prosthesis-Related Infections; D0120... | Obesity surgery | 2,006 | |
Trampoline-related injury in children. | OBJECTIVES
To quantify and describe trampoline-related injuries in children attending an urban pediatric emergency department.
METHODS
Retrospective cohort study of consecutive patients attending a children's emergency department with trampoline-related injuries over a 3-month period (May-July 2005).
RESULTS
One hu... | 10.1097/01.pec.0000221339.26873.14 | 16,983,249 | D000293:Adolescent; D001265:Athletic Injuries; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006173:Gymnastics; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies | Pediatric emergency care | 2,006 | |
Indications for intrastromal corneal ring segments in ectasia after laser in situ keratomileusis. | PURPOSE
To evaluate clinical results of intrastromal corneal ring segments (ICRS) in a large series of post-laser in situ keratomileusis (LASIK) ectasia and determine which clinical parameters were related to the success of this technique.
SETTINGS
Vissum Corporation and Clínica Baviera Group, Alicante, Spain.
DESI... | 23,073,479 | D000328:Adult; D000368:Aged; D003316:Corneal Diseases; D003319:Corneal Stroma; D004108:Dilatation, Pathologic; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D012189:Retr... | Journal of cataract and refractive surgery | 2,012 | ||
Isolation and in silico functional analysis of MtATP6, a 6-kDa subunit of mitochondrial F₁F0-ATP synthase, in response to abiotic stress. | Mitochondrial F(1)F(0)-ATP synthase is a key enzymatic complex of energy metabolism that provides ATP for the cell. Subunits of this enzyme over-express under stress conditions. Little is known about the structure and regulatory mechanism of the F(0) portion of this enzyme. We isolated the full-length coding sequen... | 10.4238/2012.October.4.3 | 23,096,681 | D017360:Arabidopsis; D001483:Base Sequence; D019295:Computational Biology; D018076:DNA, Complementary; D004579:Electron Transport; D004587:Electrophoresis, Agar Gel; D005091:Exons; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D007438:Introns; D007492:Iran; D008928:Mitochondria; D025261:Mitochondrial... | Genetics and molecular research : GMR | 2,012 | D018076:DNA, Complementary; D021122:Protein Subunits; D014157:Transcription Factors; C474451:F1F0-ATP synthase; D025261:Mitochondrial Proton-Translocating ATPases |
Financial Attributes, Environmental Performance, and Environmental Disclosure in China. | Contest between the international or national enterprises stimulates the formation of innovative or improved products or of well-organized processes. Nevertheless, reliance on carbon-based materials and energy emission sources has been highlighted as a primary problem of the 21st century. The current study examines the... | 10.3390/ijerph17238796 | 33,256,162 | D002244:Carbon; D002681:China; D003247:Conservation of Natural Resources; D030881:Disclosure; D004736:Energy-Generating Resources | International journal of environmental research and public health | 2,020 | D002244:Carbon |
GABAergic neurons differentiated from BDNF- and Dlx2-modified neural stem cells restore disrupted neural circuits in brainstem stroke. | BACKGROUND
Brainstem stroke causes severe and persistent neurological impairment. Due to the limited spontaneous recovery and regeneration of the disrupted neural circuits, transplantation of exogenous neural stem cells (NSCs) was an alternative, while there were limitations for primitive NSCs.
METHODS
We established... | 10.1186/s13287-023-03378-5 | 37,365,654 | D051379:Mice; D000818:Animals; D019208:Brain-Derived Neurotrophic Factor; D058953:Neural Stem Cells; D002454:Cell Differentiation; D004195:Disease Models, Animal; D059330:GABAergic Neurons; D020521:Stroke | Stem cell research & therapy | 2,023 | D019208:Brain-Derived Neurotrophic Factor |
Losartan improves recovery of contraction and inhibits transient inward current in a cellular model of cardiac ischemia and reperfusion. | Losartan, a selective angiotensin II (AII) type I receptor antagonist, may protect against myocardial stunning and arrhythmia in ischemia and reperfusion. To examine the cellular basis for these protective actions, we studied effects of losartan and AII on contractile and electrical activity of ventricular myocytes exp... | 11,046,108 | D000804:Angiotensin II; D057911:Angiotensin Receptor Antagonists; D000818:Animals; D000889:Anti-Arrhythmia Agents; D002121:Calcium Channel Blockers; D020746:Calcium Channels, L-Type; D020747:Calcium Channels, T-Type; D006168:Guinea Pigs; D006352:Heart Ventricles; D019808:Losartan; D008297:Male; D009200:Myocardial Contr... | The Journal of pharmacology and experimental therapeutics | 2,000 | D057911:Angiotensin Receptor Antagonists; D000889:Anti-Arrhythmia Agents; D002121:Calcium Channel Blockers; D020746:Calcium Channels, L-Type; D020747:Calcium Channels, T-Type; D044140:Receptor, Angiotensin, Type 1; D044139:Receptor, Angiotensin, Type 2; D000804:Angiotensin II; D019808:Losartan | |
Exposure to benzo[a]pyrene triggers distinct patterns of microRNA transcriptional profiles in aquatic firefly Aquatica wuhana (Coleoptera: Lampyridae). | Larval aquatic fireflies in fresh water are adversely affected by water pollutants such as benzo(a)pyrene (BaP). However, their response to BaP stress at the microRNA (miRNA)-regulatory level remains unknown. Here, transcriptomes containing 31,872 genes and six miRNA transcriptional profiles were obtained for Aquatica ... | 10.1016/j.jhazmat.2020.123409 | 32,763,701 | D000818:Animals; D001564:Benzo(a)pyrene; D001517:Coleoptera; D048888:Fireflies; D035683:MicroRNAs; D059467:Transcriptome; D014874:Water Pollutants, Chemical | Journal of hazardous materials | 2,021 | D035683:MicroRNAs; D014874:Water Pollutants, Chemical; D001564:Benzo(a)pyrene |
[Mammalian DNA methylation and its roles during the induced re-programming of somatic cells]. | The technology of induced pluripotent stem cell (iPS) provides the possibility to reverse the terminal differentiated cells to pluripotent stem cells, and is therefore of great importance in both the theoretical research of stem cells and regenerative medicine. However, the efficiency of current induced reprogramming m... | 24,846,992 | D000818:Animals; D065150:Cellular Reprogramming; D019175:DNA Methylation; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D008322:Mammals; D053652:Nuclear Transfer Techniques | Yi chuan = Hereditas | 2,014 | ||
The complete structure and pro-inflammatory activity of the lipooligosaccharide of the highly epidemic and virulent gram-negative bacterium Burkholderia cenocepacia ET-12 (strain J2315). | Members of genus Burkholderia include opportunistic Gram-negative bacteria that are responsible for serious infections in immunocompromised and cystic fibrosis (CF) patients. The Burkholderia cepacia complex is a group of microorganisms composed of at least nine closely related genomovars. Among these, B. cenocepacia i... | 10.1002/chem.200601406 | 17,219,455 | D019121:Burkholderia Infections; D016956:Burkholderia cepacia; D003550:Cystic Fibrosis; D004196:Disease Outbreaks; D006801:Humans; D007249:Inflammation; D008070:Lipopolysaccharides; D009682:Magnetic Resonance Spectroscopy; D020298:U937 Cells; D014774:Virulence | Chemistry (Weinheim an der Bergstrasse, Germany) | 2,007 | D008070:Lipopolysaccharides |
Medical residents' and teachers' perceptions of the digital format of nation-wide didactic courses for psychiatry residents in Sweden: a survey-based observational study. | BACKGROUND
This study aimed to explore residents' and teachers' perceptions of the digital format of Metis (a national education network in Sweden) didactic courses for psychiatry residents in Sweden to guide post-pandemic curriculum development.
METHODS
An online attitude survey was developed and sent out to 725 res... | 10.1186/s12909-022-03989-1 | 36,604,728 | D006801:Humans; D007396:Internship and Residency; D013548:Sweden; D011795:Surveys and Questionnaires; D003479:Curriculum; D011570:Psychiatry | BMC medical education | 2,023 | |
[Relationship between group G chromosomes, especially chromosome 21, and the sensitivity of human cells to Coxsackie B viruses]. | The R-method of differential chromosome staining by length was applied to comparative karyological studies on the culture of J 96 human cells susceptible to enteroviruses, and on the J 41 cell line derived from this culture and possessing high specific resistance to Coxsackie B viruses. Karyotype of the J 41 cell line ... | 214,186 | D002460:Cell Line; D002874:Chromosome Mapping; D002904:Chromosomes, Human, 21-22 and Y; D029822:Enterovirus B, Human; D005802:Genes, MHC Class II; D006801:Humans | Biulleten' eksperimental'noi biologii i meditsiny | 1,978 | ||
The craniofacial morphology of the parents of children with orofacial clefting: a systematic review of cephalometric studies. | OBJECTIVE
To systematically review the cephalometric studies investigating the craniofacial morphology of the parents of children with orofacial clefting (OFC).
SEARCH STRATEGY
The search strategy was based on the keywords 'parent', cephalometry', and 'cleft', identifying 17 studies, of which 15 'case/control' studie... | 10.1093/ortho/29.1.23 | 11,907,306 | D000328:Adult; D000704:Analysis of Variance; D002508:Cephalometry; D002648:Child; D002972:Cleft Palate; D016000:Cluster Analysis; D016002:Discriminant Analysis; D005145:Face; D019066:Facies; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents | Journal of orthodontics | 2,002 | |
Modeling cell elongation during germ band retraction: cell autonomy versus applied anisotropic stress. | The morphogenetic process of germ band retraction in Drosophila embryos involves coordinated movements of two epithelial tissues - germ band and amnioserosa. The germ band shortens along its rostral-caudal or head-to-tail axis, widens along its perpendicular dorsal-ventral axis, and uncurls from an initial 'U' shape. T... | 10.1088/1367-2630/16/5/055003 | 24,839,394 | New journal of physics | 2,014 | ||
Photoferrotrophs thrive in an Archean Ocean analogue. | Considerable discussion surrounds the potential role of anoxygenic phototrophic Fe(II)-oxidizing bacteria in both the genesis of Banded Iron Formations (BIFs) and early marine productivity. However, anoxygenic phototrophs have yet to be identified in modern environments with comparable chemistry and physical structure ... | 10.1073/pnas.0805313105 | 18,838,679 | D000693:Anaerobiosis; D001105:Archaea; D019414:Chlorobi; D004777:Environment; D007214:Indonesia; D007501:Iron; D008027:Light; D008386:Marine Biology; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D013440:Sulfides; D013472:Sunlight; D014871:Water Microbiology | Proceedings of the National Academy of Sciences of the United States of America | 2,008 | D013440:Sulfides; D007501:Iron |
[Phagocytic activity of granulocytes after UV-irradiation]. | The effect of UV-irradiation on three functions of human isolated granulocytes (viability, phagocyte activity and capacity to reduce nitrotetrazolium blue) was investigated. The phagocytosis appeared to be the most sensitive function. The number of phagocytic cells was decreased under UV-doses as low as 0.63 kJ.m-2. Ce... | 2,631,954 | D006098:Granulocytes; D006801:Humans; D066298:In Vitro Techniques; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis; D014466:Ultraviolet Rays | Biofizika | 1,989 | D009580:Nitroblue Tetrazolium | |
Chemical composition of Brazilian chia seeds grown in different places. | This study investigated and compared the occurrence and concentration of macronutrients, moisture, ash, dietary fiber, fatty acids, minerals, carotenoids, vitamins, flavonoids, phenolic compounds, antioxidant activity, phytate and tannin in Brazilian chia seeds grown in the states of Mato Grosso (MT) and Rio Grande do ... | 10.1016/j.foodchem.2016.10.115 | 27,979,151 | D001938:Brazil; D002338:Carotenoids; D005227:Fatty Acids; D010084:Oxidation-Reduction; D010636:Phenols; D027544:Salvia; D012639:Seeds; D013634:Tannins; D014810:Vitamin E | Food chemistry | 2,017 | D005227:Fatty Acids; D010636:Phenols; D013634:Tannins; D014810:Vitamin E; D002338:Carotenoids |
Interaction between fosamprenavir, with and without ritonavir, and nevirapine in human immunodeficiency virus-infected subjects. | Fosamprenavir (FPV) with and without ritonavir (RTV) was added to the antiretroviral regimens of human immunodeficiency virus-infected subjects receiving nevirapine (NVP) to evaluate this drug interaction. Significant reductions in plasma amprenavir exposure (25 to 35%) were observed following coadministration of 1,400... | 10.1128/AAC.00093-06 | 16,940,117 | D000328:Adult; D019380:Anti-HIV Agents; D002219:Carbamates; D004347:Drug Interactions; D005260:Female; D005663:Furans; D006678:HIV; D015658:HIV Infections; D017320:HIV Protease Inhibitors; D006801:Humans; D008297:Male; D019829:Nevirapine; D010755:Organophosphates; D018894:Reverse Transcriptase Inhibitors; D019438:Riton... | Antimicrobial agents and chemotherapy | 2,006 | D019380:Anti-HIV Agents; D002219:Carbamates; D005663:Furans; D017320:HIV Protease Inhibitors; D010755:Organophosphates; D018894:Reverse Transcriptase Inhibitors; D013449:Sulfonamides; D019829:Nevirapine; D019438:Ritonavir; C426859:fosamprenavir |
Teachers' experiences supporting children after traumatic exposure. | Teachers can be instrumental in supporting children's recovery after trauma, but some work suggests that elementary school teachers are uncertain about their role and about what to do to assist children effectively after their students have been exposed to traumatic stressors. This study examined the extent to which te... | 10.1002/jts.20709 | 22,354,512 | D000293:Adolescent; D000328:Adult; D002648:Child; D005178:Faculty; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D012944:Social Support; D011795:Surveys and Questionnaires; D014947:Wounds and Injuries; D055815:Young Adult | Journal of traumatic stress | 2,012 | |
[Adenocarcinoma of the ampulla of Vater revealed by prurigo]. | Chronic prurigo may reveal several internal diseases. Its association with a solid neoplasia is rare. We report an exceptional case of chronic prurigo revealing surgically curable adenocarcinoma of the ampulla of Vater. Our study involved a 70-year old patient, with no particular previous history, who was hospitalized ... | 10.11604/pamj.2017.28.154.13846 | 29,564,035 | D000230:Adenocarcinoma; D000368:Aged; D014670:Ampulla of Vater; D002908:Chronic Disease; D003138:Common Bile Duct Neoplasms; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011536:Prurigo; D014057:Tomography, X-Ray Computed | The Pan African medical journal | 2,017 | |
Soft tissue management for primary closure in guided bone regeneration: surgical technique and case report. | A surgical technique with the objective of obtaining and maintaining soft tissue closure over membranes used for guided bone regeneration is described. This procedure achieves primary closure in extraction sockets or in association with immediate implants without creating mucogingival problems around adjacent teeth. | 9,048,459 | D000539:Alveolar Process; D001861:Bone Regeneration; D005881:Gingiva; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008567:Membranes, Artificial; D013524:Surgical Flaps; D014081:Tooth Extraction | The International journal of oral & maxillofacial implants | 1,997 | D008567:Membranes, Artificial | |
Comparing the effect of clozapine and risperidone on cue reactivity in male patients with schizophrenia and a cannabis use disorder: A randomized fMRI study. | OBJECTIVE
Cannabis use disorders (CUDs) are highly comorbid in patients with schizophrenia and associated with poor outcome. Clozapine has been put forward as the first choice antipsychotic in this patient group. However, little is known about the mechanisms underlying the assumed superiority of clozapine.
METHODS
A ... | 10.1016/j.schres.2017.03.030 | 28,351,544 | D014150:Antipsychotic Agents; D001921:Brain; D001931:Brain Mapping; D003024:Clozapine; D015897:Comorbidity; D066249:Craving; D003463:Cues; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D002189:Marijuana Abuse; D055118:Medication Adherence; D018967:Risperidone; D012559:Schizophrenia; D016896:Treatmen... | Schizophrenia research | 2,018 | D014150:Antipsychotic Agents; D003024:Clozapine; D018967:Risperidone |
Differentiating true versus pseudo left ventricular aneurysm: a case report and review of diagnostic strategies. | The differentiation of left ventricular pseudoaneurysm from true aneurysm is sometimes difficult. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is clinically impor... | 10.1097/01.crd.0000233756.66532.45 | 17,053,370 | D017541:Aneurysm, False; D017023:Coronary Angiography; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006322:Heart Aneurysm; D006352:Heart Ventricles; D006801:Humans; D008875:Middle Aged; D011859:Radiography | Cardiology in review | 2,006 | |
Trust in vaccines and medicines in Uganda. | Trust underlies numerous decisions in health care, affecting vaccine uptake as well as care seeking rates, treatment adherence, and health outcomes. Although trust in the doctor-patient relationship has garnered much attention, trust in health care commodities such as vaccines and medicines has rarely been examined. We... | 10.1016/j.vaccine.2019.07.022 | 31,447,127 | D000328:Adult; D003142:Communication; D003430:Cross-Sectional Studies; D003657:Decision Making; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D010342:Patient Acceptance of Health Care; D010817:Physician-Patient Relations; D035502:Trust; D014454:Uganda; D014611:Vaccination;... | Vaccine | 2,019 | D014612:Vaccines |
The detergent-insoluble microdomains, rafts, can be used as an effective immunogen. | Detergent-insoluble microdomains, or rafts, act as a platform to transduce signals from the extracellular space into the cytoplasm. In the process of developing monoclonal antibodies against raft molecules for the purpose of studying the molecular mechanism of raft-mediated signaling, we observed the uniqueness and cer... | 10.1007/s10719-007-9083-7 | 18,074,225 | D000818:Animals; D000906:Antibodies; D000941:Antigens; D045744:Cell Line, Tumor; D002855:Chromatography, Thin Layer; D003902:Detergents; D004797:Enzyme-Linked Immunosorbent Assay; D005434:Flow Cytometry; D006017:Glycolipids; D006801:Humans; D021962:Membrane Microdomains; D051379:Mice; D051381:Rats; D012995:Solubility | Glycoconjugate journal | 2,008 | D000906:Antibodies; D000941:Antigens; D003902:Detergents; D006017:Glycolipids |
Self-healing of hierarchical materials. | We present a theoretical and numerical analysis of the mechanical behavior of self-healing materials using an analytical model and numerical calculations both based on a Hierarchical Fiber Bundle Model, and applying them to graphene- or carbon-nanotube-based materials. The self-healing process can be described essentia... | 10.1021/la403497z | 24,364,755 | D040761:Biomimetic Materials; D003198:Computer Simulation; D006108:Graphite; D008956:Models, Chemical; D037742:Nanotubes, Carbon; D013314:Stress, Mechanical | Langmuir : the ACS journal of surfaces and colloids | 2,014 | D037742:Nanotubes, Carbon; D006108:Graphite |
Classification models for identifying substances exhibiting acute contact toxicity in honeybees (Apis mellifera)$. | Nowadays, environmental and biological endpoints can be predicted with in silico approaches if sufficient experimental data of good quality are available. Since the experimental evaluation of acute contact toxicity towards honeybees (Apis mellifera) is a complex and expensive assay, the computational models that follow... | 10.1080/1062936X.2018.1513953 | 30,220,217 | D000818:Animals; D001516:Bees; D008958:Models, Molecular; D016571:Neural Networks, Computer; D010575:Pesticides; D021281:Quantitative Structure-Activity Relationship | SAR and QSAR in environmental research | 2,018 | D010575:Pesticides |
The Use of Telephone Consultation in Primary Health Care During COVID-19 Pandemic, Oman: Perceptions from Physicians. | INTRODUCTION
To enforce physical distancing measures during COVID-19, Telephone Consultation (TC), a form of telemedicine, was initiated as an alternative technology to face to face consultation in primary health care (PHC) in Muscat, Oman. This study aims to explore the perceptions of physicians about the use of TC wi... | 10.1177/2150132720976480 | 33,307,943 | D000328:Adult; D001291:Attitude of Health Personnel; D000086382:COVID-19; D003219:Confidentiality; D005260:Female; D006801:Humans; D007318:Inservice Training; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009850:Oman; D058873:Pandemics; D010819:Physician's Role; D010817:Physician-Patient Relations; D... | Journal of primary care & community health | 2,020 | |
Extraction chromatography of 225Ac and lanthanides on N,N-dioctyldiglycolamic acid /1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide solvent impregnated resin. | The alpha-emitter 225Ac (t1/2 = 9.92 d) is currently under development for targeted alpha-particle therapy of cancer, and accelerator production of 225Ac via proton irradiation of thorium targets requires robust separations of 225Ac from chemically similar fission product lanthanides. Additionally, the lanthanide eleme... | 10.1016/j.chroma.2020.461219 | 32,540,068 | D000186:Actinium; D002852:Chromatography, Ion Exchange; D006016:Glycolates; D007093:Imidazoles; D052578:Ionic Liquids; D028581:Lanthanoid Series Elements; D016062:Porosity; D012997:Solvents; D013054:Spectrophotometry, Atomic | Journal of chromatography. A | 2,020 | C525963:1-butyl-3-methylimidazolium; C000615155:Actinium-225; D006016:Glycolates; D007093:Imidazoles; D052578:Ionic Liquids; D028581:Lanthanoid Series Elements; C581676:N,N-dioctyldiglycol amic acid; D012997:Solvents; D000186:Actinium |
The Risk of Mycobacterium tuberculosis Transmission from Pediatric Index Cases to School Pupils. | This study is the largest report on Mycobacterium tuberculosis transmission rate (TR) from children with pulmonary tuberculosis to school pupils. Higher TR (around 21.6%) was observed in contacts of smear-positive children. TR from pediatric smear-negative index cases was around 0. If our data are confirmed, school con... | 10.1097/INF.0000000000001492 | 28,403,060 | D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009169:Mycobacterium tuberculosis; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012307:Risk Factors; D012574:Schools; D013183:Sputum... | The Pediatric infectious disease journal | 2,017 | |
Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-like Mechanism of Action. | RNA therapeutics are poised to revolutionize medicine. To unlock the full potential of RNA drugs, safe and efficient (nano)formulations to deliver them inside target cells are required. Endosomal sequestration of nanocarriers represents a major bottleneck in nucleic acid delivery. Gaining more detailed information on t... | 10.1021/acsnano.0c04489 | 33,724,778 | D000818:Animals; D002289:Carcinoma, Non-Small-Cell Lung; D045744:Cell Line, Tumor; D008175:Lung Neoplasms; D037701:Pulmonary Surfactant-Associated Protein B; D034741:RNA, Small Interfering | ACS nano | 2,021 | D037701:Pulmonary Surfactant-Associated Protein B; D034741:RNA, Small Interfering |
Lessons Learned From Neuroimaging Studies of Copy Number Variants: A Systematic Review. | Pathogenic copy number variants (CNVs) and aneuploidies alter gene dosage and are associated with neurodevelopmental psychiatric disorders such as autism spectrum disorder and schizophrenia. Brain mechanisms mediating genetic risk for neurodevelopmental psychiatric disorders remain largely unknown, but there is a rapid... | 10.1016/j.biopsych.2021.05.028 | 34,509,290 | D000067877:Autism Spectrum Disorder; D056915:DNA Copy Number Variations; D006801:Humans; D008279:Magnetic Resonance Imaging; D059906:Neuroimaging; D012559:Schizophrenia | Biological psychiatry | 2,021 | |
Paraffin section immunohistochemistry as an adjunct to morphologic analysis in the diagnosis of cutaneous lymphoid infiltrates. | In the skin, separation of selected lymphomas from lymphoid hyperplasia can be challenging. The authors examined 45 cutaneous lymphomas, excluding mycosis fungoides (26 small lymphocytic or mixed tumors; 19 large cell lymphomas), 10 "atypical" lesions, and 40 lesions of presumed lymphoid hyperplasia, comparing morpholo... | 10.1111/j.1600-0560.1994.tb00717.x | 7,699,114 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015703:Antigens, CD; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008214:Lymphocytes; D008223:Lymphoma; D008875:Middle Aged; D016612:Paraffin Embedding; D018... | Journal of cutaneous pathology | 1,994 | D015703:Antigens, CD; D018809:Proliferating Cell Nuclear Antigen |
Large-system acute care transformation. | All organizations are steeped in making delivery model changes to address the changing health care landscape specific to the expectations of health care reform. Too often, these changes focus solely on improving processes rather than developing creative and innovative work processes that decrease waste and increase qua... | 10.1097/NAQ.0000000000000007 | 24,317,032 | D018166:Health Care Reform; D006296:Health Services; D006801:Humans; D009936:Organizational Innovation; D010043:Outcome and Process Assessment, Health Care; D010358:Patient Participation; D058991:Patient Protection and Affordable Care Act | Nursing administration quarterly | 2,014 | |
Effects of percutaneous transluminal coronary angioplasty on segmental left ventricular function in patients with acute myocardial infarction. | In order to investigate the usefulness of percutaneous transluminal coronary angioplasty (PTCA) on subsequent left ventricular (LV) function in patients with acute myocardial infarction (AMI), regional ejection fraction (REF) was calculated from the left ventriculogram and compared in the acute and chronic phases (4 we... | 10.1536/ihj.28.467 | 2,960,837 | D000800:Angioplasty, Balloon; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction; D013318:Stroke Volume; D013997:Time Factors; D014568:Urokinase-Type Plasminogen Activator | Japanese heart journal | 1,987 | D014568:Urokinase-Type Plasminogen Activator |
Anion-induced disproportionation of Th(III) complexes to form Th(II) and Th(IV) products. | A new synthesis of Th(II) complexes has been identified involving addition of simple MX salts (M = Li, Na, K; X = H, Cl, Me, N3) to Cp''3ThIII [Cp'' = [C5H3(SiMe3)2] in the presence of 18-crown-6 or 2.2.2-cryptand, forming [M(chelate)][Cp''3ThII] and Cp''3ThIVX. Cptet3ThIII (Cptet = C5Me4H) reacts with KH to form Cptet... | 10.1039/d2cc01272c | 35,403,646 | Chemical communications (Cambridge, England) | 2,022 | ||
Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse. | Transgenic Tg.AC (v-Ha-ras ) mice develop skin tumors in response to specific carcinogens and tumor promoters. The Tg.AC mouse carries the coding sequence of v-Ha ras, linked to a zeta-globin promoter and an SV40 polyadenylation signal sequence. The transgene confers on these mice the property of genetically initiated ... | 10.1093/carcin/22.4.651 | 11,285,202 | D000367:Age Factors; D000375:Aging; D000818:Animals; D002273:Carcinogens; D002499:Centrifugation, Density Gradient; D005260:Female; D005434:Flow Cytometry; D011905:Genes, ras; D005914:Globins; D019012:Integrin beta1; D015603:Keratinocytes; D051379:Mice; D008822:Mice, Transgenic; D009381:Neoplasms, Radiation-Induced; D0... | Carcinogenesis | 2,001 | D002273:Carcinogens; D019012:Integrin beta1; D005914:Globins; D013755:Tetradecanoylphorbol Acetate |
The activated keratinocyte: up regulation of cell adhesion and migration during wound healing. | Keratinocytes play different roles in normal and wounded skin. In normal skin, these cells are specialized for differentiation. In wounded skin, they are specialized for migration. This article discusses the idea that migratory-competent keratinocytes are "activated." Changes that characterize the activation process in... | 2,254,973 | D002448:Cell Adhesion; D002465:Cell Movement; D002478:Cells, Cultured; D003094:Collagen; D006801:Humans; D015603:Keratinocytes; D016029:Receptors, Very Late Antigen; D012867:Skin; D015854:Up-Regulation; D014945:Wound Healing | The Journal of trauma | 1,990 | D016029:Receptors, Very Late Antigen; D003094:Collagen | |
Nonparametric Regression With Missing Outcomes Using Weighted Kernel Estimating Equations. | We consider nonparametric regression of a scalar outcome on a covariate when the outcome is missing at random (MAR) given the covariate and other observed auxiliary variables. We propose a class of augmented inverse probability weighted (AIPW) kernel estimating equations for nonparametric regression under MAR. We show ... | 10.1198/jasa.2010.tm08463 | 23,144,520 | Journal of the American Statistical Association | 2,010 | ||
Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review. | Gene therapy can be defined as the transfer of genetic material into a cell for therapeutic purposes. Cytosine deaminase (CD) transferred into tumor cells by an adenoviral vector (Ad.CD), can convert the antifungal drug fluorocytosine (5-FC) to the antimetabolite 5-fluorouracil (5-FU), which kills not only the transfec... | 10.1038/cgt.2012.36 | 22,744,209 | D000256:Adenoviridae; D000368:Aged; D000740:Anemia; D000818:Animals; D000964:Antimetabolites, Antineoplastic; D024201:Bystander Effect; D002289:Carcinoma, Non-Small-Cell Lung; D043525:Cytosine Deaminase; D005437:Flucytosine; D005472:Fluorouracil; D041722:Genes, Transgenic, Suicide; D015316:Genetic Therapy; D006801:Huma... | Cancer gene therapy | 2,012 | D000964:Antimetabolites, Antineoplastic; D011355:Prodrugs; D005437:Flucytosine; D043525:Cytosine Deaminase; D005472:Fluorouracil |
Spontaneous Remission and Concomitant Progression in a Patient with DLBCL. | Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma. Although DLBCL can be cured in more than half of all patients, up to 50% of patients become refractory to initial treatment or relapse after complete remission. We present a case of complete spontaneous remission of some tumors and concomitant n... | 10.3390/diagnostics10110950 | 33,202,678 | Diagnostics (Basel, Switzerland) | 2,020 | ||
Transferase Activity of Lactobacillal and Bifidobacterial β-Galactosidases with Various Sugars as Galactosyl Acceptors. | The β-galactosidases from Lactobacillus reuteri L103 (Lreuβgal), Lactobacillus delbrueckii subsp. bulgaricus DSM 20081 (Lbulβgal), and Bifidobacterium breve DSM 20281 (Bbreβgal-I and Bbreβgal-II) were investigated in detail with respect to their propensity to transfer galactosyl moieties onto lactose, its hydrolysis pr... | 10.1021/acs.jafc.5b06009 | 26,975,338 | D000116:Acetylgalactosamine; D000117:Acetylglucosamine; D001644:Bifidobacterium; D005688:Galactosamine; D005690:Galactose; D005944:Glucosamine; D005947:Glucose; D007778:Lactobacillus; D052200:Limosilactobacillus reuteri; D007785:Lactose; D009844:Oligosaccharides; D013379:Substrate Specificity; D014166:Transferases; D00... | Journal of agricultural and food chemistry | 2,016 | D009844:Oligosaccharides; D005688:Galactosamine; D014166:Transferases; D001616:beta-Galactosidase; D005947:Glucose; D007785:Lactose; D000116:Acetylgalactosamine; D005944:Glucosamine; D000117:Acetylglucosamine; D005690:Galactose |
Using anti-PD-L1 antibody conjugated gold nanoshelled poly (Lactic-co-glycolic acid) nanocapsules loaded with doxorubicin: A theranostic agent for ultrasound imaging and photothermal/chemo combination therapy of triple negative breast cancer. | Triple negative breast cancer (TNBC) has the worst prognosis of all breast cancers, and it is difficult to progress through traditional chemotherapy. Therefore, the treatment of TNBC urgently requires agents with effective diagnostic and therapeutic capabilities. In this study, we obtained programmed death-ligand 1 (PD... | 10.1002/jbm.a.37638 | 37,941,485 | Journal of biomedical materials research. Part A | 2,023 | ||
Intravascular lymphomatosis of the skin as a manifestation of recurrent B-cell lymphoma. | Intravascular lymphomatosis (IVL) is a rare type of lymphoma with a poor prognosis. Its distinctive clinical and histopathologic features are generated by the proliferation of neoplastic mononuclear cells within blood vessels. We describe a patient with IVL of the skin as a manifestation of a recurrent diffuse large B-... | 10.1067/mjd.2003.112 | 12,582,370 | D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D017809:Fatal Outcome; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D016393:Lymphoma, B-Cell; D008562:Membrane Glycoproteins; D016609:Neoplasms, Second Primary; D012008:Recurrence; D012878:Skin Neoplasms; D014516:Ureteral Neoplasms; D... | Journal of the American Academy of Dermatology | 2,003 | D008562:Membrane Glycoproteins |
Nano-Cu-Mediated Multi-Site Approach to Ultrafine MoO2 Nanoparticles on Poly(diallyldimethylammonium chloride)-Decorated Reduced Graphene Oxide for Hydrogen Evolution Electrocatalysis. | Catalysts with high atom utilization efficiency accompanied by improved reactivity and durability are highly desired. Metallic MoO2 with its small size easily agglomerates, making it difficult to use in water splitting to obtain hydrogen by electrolysis. Here, the nano-Cu-mediated multi-site method is proposed to prepa... | 10.1002/cssc.201802491 | 30,460,758 | ChemSusChem | 2,019 | ||
Crocetin, dimethylcrocetin, and safranal bind human serum albumin: stability and antioxidative properties. | Crocetin (CRT) and dimethylcrocetin (DMCRT) are derived from crocins which are found in the stigmas of saffron (Crocus sativus L.), while safranal is the main component of saffron's essential oil. The aim of the present study was to examine their interaction with human serum albumin in aqueous solution at physiological... | 10.1021/jf062638l | 17,263,501 | D000975:Antioxidants; D002338:Carotenoids; D053138:Cyclohexenes; D004355:Drug Stability; D006801:Humans; D006860:Hydrogen Bonding; D011485:Protein Binding; D012709:Serum Albumin; D013053:Spectrophotometry; D017550:Spectroscopy, Fourier Transform Infrared; D013729:Terpenes; D014801:Vitamin A | Journal of agricultural and food chemistry | 2,007 | D000975:Antioxidants; D053138:Cyclohexenes; D012709:Serum Albumin; D013729:Terpenes; C487773:trans-sodium crocetinate; D014801:Vitamin A; D002338:Carotenoids; C087963:safranal; C519269:dimethylcrocetin |
Heterogeneous expression of multiple putative patterning genes by single cells from the chick hindbrain. | The metameric organization of the vertebrate hindbrain into rhombomeres appears to result from the patterned expression of several transcription factors and putative signaling molecules. We have applied a refined single-cell reverse transcription-polymerase chain reaction strategy to examine the molecular logic propose... | 10.1006/dbio.1997.8717 | 9,398,439 | D000818:Animals; D019521:Body Patterning; D002454:Cell Differentiation; D002642:Chick Embryo; D017931:DNA Primers; D004268:DNA-Binding Proteins; D051767:Early Growth Response Protein 2; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D018398:Homeodomain Proteins; D017403:In Situ Hybridizatio... | Developmental biology | 1,997 | D017931:DNA Primers; D004268:DNA-Binding Proteins; D051767:Early Growth Response Protein 2; D018398:Homeodomain Proteins; C490111:Hoxb2 protein, mouse; C513262:Hoxb4 protein, mouse; D012333:RNA, Messenger; D014157:Transcription Factors; D011494:Protein Kinases; D048670:MAP Kinase Kinase 4; C482559:MAP2K4 protein, human... |
A comparative study of the protein pattern in serum and synovial fluid. | A routine program for evaluation of the protein pattern in serum and synovial fluid has been tested on 25 patients in a consecutive study. The program comprised agar gel electrophoresis, total protein and albumin determination, and immunochemical determination of antitrypsin, orosomucoid, haptoglobin, IgR, and IgA. Lin... | 10.3109/03009747509165262 | 1,198,078 | D000418:Albumins; D001168:Arthritis; D001172:Arthritis, Rheumatoid; D001798:Blood Proteins; D006242:Haptoglobins; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D009961:Orosomucoid; D010003:Osteoarthritis; D011506:Proteins; D012709:Serum Albumin; D013582:Synovial Fluid; D014361:Trypsin Inhibitors | Scandinavian journal of rheumatology | 1,975 | D000418:Albumins; D001798:Blood Proteins; D006242:Haptoglobins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D009961:Orosomucoid; D011506:Proteins; D012709:Serum Albumin; D014361:Trypsin Inhibitors |
Laboratory animal models for human scrub typhus. | A wide variety of animals have been utilized in an attempt to provide the information necessary to bring scrub typhus to the point where it is no longer a threat to man. The laboratory mouse is usually the animal of choice for the study of this disease. The discovery that certain strains of inbred mice are genetically ... | 3,534,444 | D000818:Animals; D000830:Animals, Laboratory; D002520:Cercopithecidae; D006224:Cricetinae; D004195:Disease Models, Animal; D004285:Dogs; D005849:Gerbillinae; D006168:Guinea Pigs; D006801:Humans; D051379:Mice; D011817:Rabbits; D051381:Rats; D012612:Scrub Typhus | Laboratory animal science | 1,986 | ||
A novel thermostable neutral proteinase from Saccharomonospora canescens. | A novel thermostable neutral proteinase, called NPS, was purified to electrophoretic homogeneity from the culture broth of Saccharomonospora canescens sp. novus, strain 5. The molecular mass was determined by SDS-polyacrylamide gel electrophoresis to be 35,000 Da. The enzyme exhibits a sharp pH optimum of proteolytic a... | 10.1016/s0167-4838(97)00143-x | 9,540,792 | D000192:Actinomycetales; D000595:Amino Acid Sequence; D000626:Aminopeptidases; D002118:Calcium; D002614:Chelating Agents; D010450:Endopeptidases; D004791:Enzyme Inhibitors; D004795:Enzyme Stability; D004950:Esterases; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008666:Metalloendopeptida... | Biochimica et biophysica acta | 1,998 | D002614:Chelating Agents; D004791:Enzyme Inhibitors; D004950:Esterases; D010450:Endopeptidases; D000626:Aminopeptidases; D008666:Metalloendopeptidases; D015032:Zinc; D002118:Calcium |
Meniscal root tears: diagnosis and treatment. | Meniscal tears within the body of the meniscus or at the meniscocapsular junction represent a well-understood and manageable condition encountered in clinical practice. In comparison, however, meniscal root tears (MRTs) often go unnoticed and represent a unique injury pattern with unique biomechanical consequences. Tho... | 10.1016/j.arthro.2009.03.015 | 19,732,642 | D000293:Adolescent; D001696:Biomechanical Phenomena; D005269:Femur; D006801:Humans; D007718:Knee Injuries; D008279:Magnetic Resonance Imaging; D008592:Menisci, Tibial; D016119:Posterior Cruciate Ligament; D019651:Plastic Surgery Procedures; D000070599:Shoulder Injuries; D012785:Shoulder Joint; D000070600:Tibial Meniscu... | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association | 2,009 | |
Drink wise, age well; reducing alcohol related harm among people over 50: a study protocol. | BACKGROUND
Evidence suggests that the use of alcohol among older adults (defined as those aged 50+) has increased in recent years, with people aged 55-64 now more likely to exceed the recommended weekly guidelines than any other age group.
METHODS/ DESIGN
This is a quasi-experimental study with a before-after design.... | 10.1186/s12889-019-6525-7 | 30,819,125 | D000428:Alcohol Drinking; D005260:Female; D000073656:Healthy Aging; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires | BMC public health | 2,019 | |
Radiation therapy of testicular non-seminomas. | The prognosis of 121 patients with a non-seminoma testicular tumor MTI or MTU was assessed. The clinical lymph node involvement and the T-category of the primary had a significant bearing on prognosis, which is completely determined by pulmonary relapse. The low-risk group (9% pulmonary relapse, all curable) is charact... | 10.1016/0360-3016(82)90510-7 | 6,177,670 | D006063:Chorionic Gonadotropin; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D011379:Prognosis; D013724:Teratoma; D013736:Testicular Neoplasms; D000509:alpha-Fetoproteins | International journal of radiation oncology, biology, physics | 1,982 | D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins |
Atrial natriuretic peptide and arginine vasopressin in pregnancy and pregnancy-induced hypertension. | Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-i... | 10.1159/000185040 | 2,967,920 | D000328:Adult; D001127:Arginine Vasopressin; D009320:Atrial Natriuretic Factor; D003404:Creatinine; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia; D011247:Pregnancy; D011507:Proteinuria; D014527:Uric Acid | Nephron | 1,988 | D001127:Arginine Vasopressin; D014527:Uric Acid; D009320:Atrial Natriuretic Factor; D003404:Creatinine |
Regulation of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens by the ClpP protease. | Cyclic lipopeptides produced by Pseudomonas species exhibit potent surfactant and broad-spectrum antibiotic properties. Their biosynthesis is governed by large multimodular nonribosomal peptide synthetases, but little is known about the genetic regulatory network. This study provides, for the first time, evidence that ... | 10.1128/JB.01558-08 | 19,114,474 | D001426:Bacterial Proteins; D018441:Biofilms; D049071:Endopeptidase Clp; D015964:Gene Expression Regulation, Bacterial; D055666:Lipopeptides; D008969:Molecular Sequence Data; D011551:Pseudomonas fluorescens; D012097:Repressor Proteins; D015534:Trans-Activators; D014158:Transcription, Genetic | Journal of bacteriology | 2,009 | D001426:Bacterial Proteins; D055666:Lipopeptides; D012097:Repressor Proteins; D015534:Trans-Activators; C064778:LuxR autoinducer binding proteins; D049071:Endopeptidase Clp |
Overt and covert contrast in L2 phonology. | This paper reports results on the acquisition of the English /p/ - /b/ contrast by native speakers of Arabic. This contrast does not exist in the participants' native language (NL). The central finding of this study is that some of the research participants exhibited a covert contrast between these segments in their in... | 10.1075/jslp.1.2.06eck | 28,090,439 | Journal of second language pronunciation | 2,015 | ||
Carbon Nanodot-Sensitized Modulation of Alzheimer's β-Amyloid Self-Assembly, Disassembly, and Toxicity. | The self-assembly of amyloidogenic peptides into β-sheet-rich aggregates is a general feature of many neurodegenerative diseases, including Alzheimer's disease, which signifies the need for the effective attenuation of amyloid aggregation toward alleviating amyloid-associated neurotoxicity. This study reports that phot... | 10.1002/smll.201700983 | 28,714,246 | D000544:Alzheimer Disease; D016229:Amyloid beta-Peptides; D002244:Carbon; D002470:Cell Survival; D006801:Humans; D010446:Peptide Fragments | Small (Weinheim an der Bergstrasse, Germany) | 2,017 | D016229:Amyloid beta-Peptides; D010446:Peptide Fragments; D002244:Carbon |
A novel synthetic compound, (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-iminothiazolidin-4-one (MHY773) inhibits mushroom tyrosinase. | As part of continued efforts for the development of new tyrosinase inhibitors, (Z)-5-(substituted benzylidene)-2-iminothiazolidin-4-one derivatives (1a - 1l) were rationally synthesized and evaluated for their inhibitory potential in vitro. These compounds were designed and synthesized based on the structural attribute... | 10.1080/09168451.2018.1445518 | 29,521,165 | Bioscience, biotechnology, and biochemistry | 2,018 | ||
Dipropylacetate and hyperglycinemia. | Hyperglycinemia was induced by dipropylacetate (DPA) (dose 14-41 mg/kg per day) in 10 Finnish epileptic patients with neurologically disabling diseases of various kinds. When comparing the levels of glycine in plasma, cerebrospinal fluid and urine from the patients with 10 otherwise comparable patients, and normal valu... | 10.1055/s-0028-1085322 | 386,163 | D000293:Adolescent; D002648:Child; D004827:Epilepsy; D005998:Glycine; D006801:Humans; D014635:Valproic Acid | Neuropadiatrie | 1,979 | D014635:Valproic Acid; D005998:Glycine |
The APpendicitis PEdiatric (APPE) score: a new diagnostic tool in suspected pediatric acute appendicitis. | Our aim was to develop an APpendictis-PEdiatric score (APPE score) in quantifying risk of acute appendicitis based on combination of clinical and laboratory markers. 1025 patients were classified in: acute appendicitis (AA) and non-appendicitis. Demographic/clinical features, and laboratory were collected. They were co... | 10.4081/pmc.2019.209 | 30,961,344 | D000293:Adolescent; D001064:Appendicitis; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007249:Inflammation; D008297:Male; D012372:ROC Curve; D012189:Retrospective Studies; D012306:Risk; D012680:Sensitivity and Specificity | La Pediatria medica e chirurgica : Medical and surgical pediatrics | 2,019 | |
Descriptive study of the histopathological subtypes and programmed death-ligand 1 in metaplastic breast carcinoma. | Metaplastic Breast Carcinoma (MBC) is a rare heterogeneous group of tumors, the incidence of which is less than 1% of breast tumors. These are a unique set of tumors with varying subtypes, poor prognosis, and an increased chance of distant metastasis. We aimed to study the clinical, histomorphological, and immunohistoc... | 10.1111/tbj.14056 | 32,959,535 | D000368:Aged; D060890:B7-H1 Antigen; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D007194:India; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D018719:Receptor, ErbB-2; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone | The breast journal | 2,020 | D060890:B7-H1 Antigen; D014408:Biomarkers, Tumor; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D018719:Receptor, ErbB-2 |
Comparisons of dynamic retinoscopy measurements with a print card, a video display terminal, and a PRIO System Tester as test targets. | BACKGROUND
Dynamic retinoscopy is a common clinical test for assessment of visual function in patients with symptoms related to computer use. It has been suggested that performing dynamic retinoscopy with a fixation target resembling a computer screen may be valuable in the examination of computer users. However, such ... | 10.1016/s1529-1839(04)70050-0 | 15,117,056 | D000065:Accommodation, Ocular; D000328:Adult; D016288:Computer Terminals; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D008297:Male; D012029:Refraction, Ocular; D015203:Reproducibility of Results; D042262:Retinoscopy; D014786:Vision Disorders; D014787:Vision Tests; D014792:Visual Acuity | Optometry (St. Louis, Mo.) | 2,004 | |
Differential survival in horses requiring end-to-end jejunojejunal anastomosis compared to those requiring side-to-side jejunocaecal anastomosis. | REASONS FOR PERFORMING STUDY
Horses requiring different methods of intestinal anastomosis during equine colic surgery may have differences in mortality and morbidity.
HYPOTHESES
Horses requiring side-to-side jejunocaecal anastomosis have a higher mortality and morbidity rate than those requiring end-to-end jejunojeju... | 10.2746/042516407x171354 | 17,378,448 | D000714:Anastomosis, Surgical; D000818:Animals; D002432:Cecum; D003085:Colic; D005260:Female; D006734:Horse Diseases; D006736:Horses; D007583:Jejunum; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D016019:Survival Analysis; D013537:Sutures; D016896:Treatment Outcome | Equine veterinary journal | 2,007 | |
[p53 expression and cancer cell invasion in the distal bowel wall of patients with rectal carcinoma]. | OBJECTIVE
To determine an adequate distal bowel length to be excised for safe surgical removal of rectal carcinoma.
METHODS
p53 expression and patterns of cancer cell invasion into the bowel wall distal to the tumors were studied in 68 surgically removed rectal carcinoma specimens with immunohistochemical and routine... | 12,390,734 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012004:Rectal Neoplasms; D016159:Tumor Suppressor Protein p53 | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA | 2,002 | D016159:Tumor Suppressor Protein p53 | |
Somatostatin release from isolated ganglia of the myenteric plexus. | Somatostatin neurons of the myenteric plexus project caudad exclusively within the plexus synapsing with neurons in the same or other ganglia. Isolated ganglia offer a unique opportunity to examine peptide transmitter release from these interneurons. Ganglia were isolated from the myenteric plexus by sequential enzymat... | 10.1152/ajpgi.1989.257.2.G313 | 2,569,833 | D000818:Animals; D004246:Dimethylphenylpiperazinium Iodide; D005725:Ganglia, Autonomic; D006168:Guinea Pigs; D018738:Hexamethonium; D006584:Hexamethonium Compounds; D066298:In Vitro Techniques; D007395:Interneurons; D007422:Intestines; D008297:Male; D009130:Muscle, Smooth; D009197:Myenteric Plexus; D010477:Perfusion; D... | The American journal of physiology | 1,989 | D006584:Hexamethonium Compounds; D014660:Vasoactive Intestinal Peptide; D018738:Hexamethonium; D013004:Somatostatin; D004246:Dimethylphenylpiperazinium Iodide |
Alteration of early vascular development after ablation of cranial neural crest. | A previous study has shown that, subsequent to ablation of cranial neural crest, heart morphology and pharyngeal arch vessels (aortic arches) are altered before septation of the outflow tract normally occurs. In the present study, we concentrated on very early development of the aortic arch apparatus in the chick (incu... | 10.1002/ar.1092250306 | 2,817,439 | D000818:Animals; D001013:Aorta, Thoracic; D002319:Cardiovascular System; D002642:Chick Embryo; D006321:Heart; D008648:Mesoderm; D008855:Microscopy, Electron, Scanning; D009432:Neural Crest | The Anatomical record | 1,989 | |
Identification of a potential effector function for IgE autoantibodies in the organ-specific autoimmune disease bullous pemphigoid. | Bullous pemphigoid (BP) is an autoimmune skin disease characterized by autoantibodies against the hemidesmosomal protein BP180. In addition to IgG autoantibodies, IgE class autoantibodies have been reported in BP patients. Because animal models utilizing only IgG antibodies do not totally replicate human BP, we examine... | 10.1046/j.1523-1747.2003.12146.x | 12,713,582 | D001323:Autoantibodies; D001324:Autoantigens; D001491:Basophils; D002352:Carrier Proteins; D003094:Collagen; D003598:Cytoskeletal Proteins; D000071821:Dystonin; D006632:Histamine; D006801:Humans; D015151:Immunoblotting; D007073:Immunoglobulin E; D008856:Microscopy, Fluorescence; D009419:Nerve Tissue Proteins; D024041:N... | The Journal of investigative dermatology | 2,003 | D001323:Autoantibodies; D001324:Autoantigens; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; C486268:DST protein, human; D000071821:Dystonin; D009419:Nerve Tissue Proteins; D024041:Non-Fibrillar Collagens; D011993:Recombinant Fusion Proteins; D007073:Immunoglobulin E; D006632:Histamine; D003094:Collagen |
[Comparisons of three simple nutritional assessments applied to patients with oral and maxillofacial malignancies]. | Combined subjective and objective nutritional assessment (SNA), concise nutritional assessment (CNA), general nutritional status score (GNS), and subjective global assessment of nutritional status (SGA) were applied to assess the nutritional status of 127 patients with oral and maxillofacial malignancies. On this base ... | 9,592,299 | D005153:Facial Neoplasms; D006801:Humans; D008441:Maxillary Neoplasms; D009062:Mouth Neoplasms; D015596:Nutrition Assessment; D012015:Reference Standards | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 1,996 | ||
Targeting epidermal growth factor receptor variant III: a novel strategy for the therapy of malignant glioma. | Immunotherapy represents an exciting approach for the treatment of glioblastoma multiforme. The success of this approach depends on the identification of tumor-specific antigens that can then be exploited to target the tumor. One such antigen, the epidermal growth factor receptor variant III (EGFRvIII) is found in up t... | 10.1586/14737140.7.12s.S45 | 18,076,318 | D000818:Animals; D001932:Brain Neoplasms; D019496:Cancer Vaccines; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D016503:Drug Delivery Systems; D066246:ErbB Receptors; D005260:Female; D005910:Glioma; D006801:Humans; D007167:Immunotherapy; D008297:Male; D011379:Prognosis; D018570:Risk Assessment; D01... | Expert review of anticancer therapy | 2,007 | D019496:Cancer Vaccines; D066246:ErbB Receptors |
Leg vasoconstriction during head-up tilt in patients with autonomic failure is not abolished. | Maintaining blood pressure during orthostatic challenges is primarily achieved by baroreceptor-mediated activation of the sympathetic nervous system, which can be divided into preganglionic and postganglionic parts. Despite their preganglionic autonomic failure, spinal cord-injured individuals demonstrate a preserved p... | 10.1152/japplphysiol.01098.2010 | 21,127,209 | D000328:Adult; D000368:Aged; D001341:Autonomic Nervous System; D001342:Autonomic Nervous System Diseases; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D054971:Orthostatic Intolerance; D018667:Tilt-Table Test; D014661:Vasoconstriction | Journal of applied physiology (Bethesda, Md. : 1985) | 2,011 | |
Environmental Geometry Aligns the Hippocampal Map during Spatial Reorientation. | When a navigator's internal sense of direction is disrupted, she must rely on external cues to regain her bearings, a process termed spatial reorientation. Extensive research has demonstrated that the geometric shape of the environment exerts powerful control over reorientation behavior, but the neural and cognitive me... | 10.1016/j.cub.2016.11.046 | 28,089,516 | D000818:Animals; D001522:Behavior, Animal; D056547:CA1 Region, Hippocampal; D003463:Cues; D004192:Discrimination, Psychological; D004777:Environment; D011939:Mental Recall; D051379:Mice; D009949:Orientation; D013028:Space Perception | Current biology : CB | 2,017 | |
Obesity as potential breast cancer risk factor for postmenopausal women. | Breast cancer is the second highest prevalent cancer globally after lung cancer with 2.09 million cases during 2018. Adults about 1.9 billion were overweight and over 650 million out of these were obese during 2016. There is a significant relationship between breast cancer risk and obesity. Premature menopause and prem... | 10.1016/j.gendis.2019.09.006 | 33,997,158 | Genes & diseases | 2,021 | ||
Quantification of sonochemical and sonophysical effects in a 20 kHz probe-type sonoreactor: Enhancing sonophysical effects in heterogeneous systems with milli-sized particles. | Even though acoustic cavitation has been widely investigated, only few researchers focused on the relationship between sonochemical and sonophysical activities and on the enhancement of sonophysical activity. In this study, sonochemical and sonophysical activities were investigated in a heterogeneous system to understa... | 10.1016/j.ultsonch.2021.105888 | 34,953,385 | Ultrasonics sonochemistry | 2,022 | ||
Autism spectrum disorder research: knowledge mapping of progress and focus between 2011 and 2022. | Background
In recent years, a large number of studies have focused on autism spectrum disorder (ASD). The present study used bibliometric analysis to describe the state of ASD research over the past decade and identify its trends and research fronts.
Methods
Studies on ASD published from 2011 to 2022 were obtained fr... | 10.3389/fpsyt.2023.1096769 | 37,181,872 | Frontiers in psychiatry | 2,023 | ||
[First-line vesico-psoas hitch ureteroneocystostomy for primary obstructive megaureter]. | Between 1989 and 1997, 23 children with primary obstructive megaureter underwent surgical repair, routinely using a vesico-psoas hitch ureteroneocystostomy. Ten of them had a antenatal diagnosis. Mean postoperative follow-up was 3 years. No postoperative obstruction and no vesicoureteric reflux occurred. Assessment of ... | 9,791,548 | D002675:Child, Preschool; D003559:Cystostomy; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D016658:Psoas Muscles; D011859:Radiography; D014513:Ureter; D014517:Ureteral Obstruction; D014519:Ureterostomy | Annales d'urologie | 1,998 | ||
Utilization of intracardiac echocardiography to access the coronary sinus for left ventricular lead placement. | This is a presentation of a case series of 10 consecutive patients undergoing implantation of cardiac resynchronization therapy defibrillator (CRT-D). Intracardiac echocardiography (ICE) is utilized to gain access to the coronary sinus. The method used is detailed with a brief discussion of observations gained from thi... | 10.1111/j.1540-8159.2005.50046.x | 15,955,180 | D000368:Aged; D000369:Aged, 80 and over; D003331:Coronary Vessels; D017147:Defibrillators, Implantable; D004452:Echocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged | Pacing and clinical electrophysiology : PACE | 2,005 | |
Binocular rivalry in autistic and socially anxious adults. | Background
Social anxiousness is a pervasive symptom in both social anxiety disorder and autism spectrum conditions. Binocular rivalry, which occurs when different images are presented to each eye, has been used to explore how visual and cognitive processing differs across various clinical diagnoses. Previous studies h... | 10.3389/fpsyt.2023.1181797 | 37,547,197 | Frontiers in psychiatry | 2,023 | ||
Study of p53 gene alteration as a biomarker to evaluate the malignant risk of Lugol-unstained lesion with non-dysplasia in the oesophagus. | Mutations of the p53 gene are detected frequently in oesophageal dysplasia and cancer. It is unclear whether Lugol-unstained lesions (LULs) with non-dysplastic epithelium (NDE) are precursors of oesophageal squamous cell carcinoma (ESCC). To study the genetic alterations of NDE in the multistep process of oesophageal c... | 10.1038/sj.bjc.6603582 | 17,285,122 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers; D004938:Esophageal Neoplasms; D004947:Esophagus; D005260:Female; D016158:Genes, p53; D006801:Humans; D007454:Iodides; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011230:Precancerous Conditions; D011446:Prospective Studies; D013194:Sta... | British journal of cancer | 2,007 | D015415:Biomarkers; D007454:Iodides; C010389:Lugol's solution |
Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. | Although large-scale approaches have identified numerous mitochondrial phosphoproteins, little is known about the mitochondrial kinases and phosphatases that regulate these phosphoproteins. Here, we identify two members of the atypical dual specificity phosphatases (DSP), DSP18 and DSP21, that are localized in mitochon... | 10.1074/jbc.M709547200 | 18,385,140 | D000818:Animals; D017209:Apoptosis; D019556:COS Cells; D002522:Chlorocebus aethiops; D045304:Cytochromes c; D003600:Cytosol; D054637:Dual-Specificity Phosphatases; D004791:Enzyme Inhibitors; D015971:Gene Expression Regulation, Enzymologic; D008297:Male; D008565:Membrane Proteins; D051379:Mice; D051336:Mitochondrial Mem... | The Journal of biological chemistry | 2,008 | D004791:Enzyme Inhibitors; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D045304:Cytochromes c; D054637:Dual-Specificity Phosphatases; D019311:Staurosporine |
Do media portrayals of obesity influence support for weight-related medical policy? | OBJECTIVE
The purpose of this research was to examine the impact of nonstigmatizing visual portrayals of obesity on support for a discriminatory weight-based medical policy.
METHOD
Participants read an online news story about a policy to deny fertility treatment to obese women that was accompanied by a nonstigmatizin... | 10.1037/a0032592 | 23,668,850 | D000328:Adult; D000368:Aged; D015992:Body Mass Index; D001835:Body Weight; D005260:Female; D006291:Health Policy; D006801:Humans; D007247:Infertility, Female; D008297:Male; D008402:Mass Media; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity; D013240:Stereotyping; D016312:Treatment Refusal; D014481:U... | Health psychology : official journal of the Division of Health Psychology, American Psychological Association | 2,014 | |
Hepatic Artery Anatomic Variations and Reconstruction in Liver Grafts Procured in Greece: The Effect on Hepatic Artery Thrombosis. | AIMS
Variations of the anatomy of donor hepatic arteries increase the number of arterial anastomoses during liver transplantation and, possibly, the incidence of hepatic artery thrombosis (HAT). In this study, we describe the arterial anatomic variations in liver grafts procured and transplanted by a single center in G... | 10.1016/j.transproceed.2019.01.078 | 30,879,555 | D000328:Adult; D000714:Anastomosis, Surgical; D063405:Anatomic Variation; D005260:Female; D006115:Greece; D006499:Hepatic Artery; D006801:Humans; D015994:Incidence; D008107:Liver Diseases; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D013927:Thrombosis; D014656:Vascular Surgical Procedures | Transplantation proceedings | 2,019 | |
[Testicular injuries: report of 31 cases]. | OBJECTIVE
To report 31 cases and 32 testicles of testicular injuries and summarize the experience of treatment.
METHODS
Thirty-one patients suffered from testicular injuries which included 26 cases of closed injuries and 5 cases of open injuries. Nine cases were treated with expectant treatment (surgical treatment we... | 16,398,370 | D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013737:Testis; D014947:Wounds and Injuries | Zhonghua nan ke xue = National journal of andrology | 2,005 | ||
Liver or Kidney Transplantation After SARS-CoV-2 Infection: Prevalence, Short-term Outcome, and Kinetics of Serum IgG Antibodies. | BACKGROUND
There is a paucity of data on the prevalence, adequate timing, and outcome of solid organ transplantation after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and the kinetics of immunoglobulin G (IgG) antibodies in these patients.
METHODS
SARS-CoV-2 antinucleocapsid (N) IgG and pol... | 10.1097/TP.0000000000003955 | 34,534,192 | D000914:Antibodies, Viral; D000086382:COVID-19; D006801:Humans; D007074:Immunoglobulin G; D016030:Kidney Transplantation; D007700:Kinetics; D008099:Liver; D015995:Prevalence; D000086402:SARS-CoV-2 | Transplantation | 2,022 | D000914:Antibodies, Viral; D007074:Immunoglobulin G |
Trigger factor assisted soluble expression of recombinant spike protein of porcine epidemic diarrhea virus in Escherichia coli. | BACKGROUND
Porcine epidemic diarrhea virus (PEDV) is a highly contagious enteric pathogen of swine. The spike glycoprotein (S) of PEDV is the major immunogenic determinant that plays a pivotal role in the induction of neutralizing antibodies against PEDV, which therefore is an ideal target for the development of subuni... | 10.1186/s12896-016-0268-7 | 27,142,206 | D000818:Animals; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D005260:Female; D015964:Gene Expression Regulation, Bacterial; D051379:Mice; D008807:Mice, Inbred BALB C; D019696:Peptidylprolyl Isomerase; D053485:Porcine epidemic diarrhea virus; D015202:Protein Engineering; D011994:Recombinant Proteins; D0... | BMC biotechnology | 2,016 | D029968:Escherichia coli Proteins; D011994:Recombinant Proteins; D014764:Viral Proteins; C403324:trigger factor, E coli; D019696:Peptidylprolyl Isomerase |
Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated. | Opioid-related fatalities involving synthetic opioids have reached unprecedented levels. This study evaluated the respiratory depressant effects of seven fentanyl analogs that have either emerged in the illicit drug supply or been identified in toxicological analyses following fatal or non-fatal intoxications. Adult ma... | 10.1016/j.bcp.2021.114805 | 34,673,011 | D000818:Animals; D005283:Fentanyl; D007040:Hypoventilation; D008297:Male; D051379:Mice; D015394:Molecular Structure; D009270:Naloxone; D009292:Narcotic Antagonists; D010991:Plethysmography; D017450:Receptors, Opioid, mu; D015656:Respiratory Mechanics | Biochemical pharmacology | 2,022 | D009292:Narcotic Antagonists; D017450:Receptors, Opioid, mu; D009270:Naloxone; D005283:Fentanyl |
SRY negative 64,XX intersex phenotype in an American saddlebred horse. | A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tiss... | 10.1016/j.tvjl.2005.11.008 | 16,386,440 | D000818:Animals; D012734:Disorders of Sex Development; D005260:Female; D005835:Genitalia; D006734:Horse Diseases; D006736:Horses; D007621:Karyotyping; D010641:Phenotype; D012733:Sex Differentiation; D051876:Sex-Determining Region Y Protein | Veterinary journal (London, England : 1997) | 2,007 | D051876:Sex-Determining Region Y Protein |
US-align: universal structure alignments of proteins, nucleic acids, and macromolecular complexes. | Structure comparison and alignment are of fundamental importance in structural biology studies. We developed the first universal platform, US-align, to uniformly align monomer and complex structures of different macromolecules-proteins, RNAs and DNAs. The pipeline is built on a uniform TM-score objective function coupl... | 10.1038/s41592-022-01585-1 | 36,038,728 | D000465:Algorithms; D046911:Macromolecular Substances; D009696:Nucleic Acids; D011506:Proteins; D012313:RNA; D016415:Sequence Alignment; D012984:Software | Nature methods | 2,022 | D046911:Macromolecular Substances; D009696:Nucleic Acids; D011506:Proteins; D012313:RNA |
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