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Problems with administration of international prostate symptom score in a developing community. | BACKGROUND
The IPSS form has been found useful for assessing symptom severity, which assists in treatment choice and in monitoring patients on therapy. The form should be self-administered and requires some level of literacy. We assessed the problems associated with its administration in a developing community.
MATER... | 10.4103/1596-3519.117628 | 24,005,590 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003950:Diagnostic Techniques, Urological; D057220:Health Literacy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D011446:Prospective Studies; D011470:Prostatic Hyperplasia; D011788:Quality of Life; D012720:Severity of Illness Index; D012959:... | Annals of African medicine | 2,013 | |
Modulation of synaptic zinc in barrel cortex by whisker stimulation. | The cortical representation of the body surface is not fixed, but rather, is continuously modified by ongoing changes in sensory experience. Although the cellular and molecular mechanisms that subserve these changes are uncertain, increasing evidence suggests that synaptically-released zinc may play a role. Zinc is rel... | 10.1016/j.neuroscience.2005.05.011 | 16,019,150 | D000818:Animals; D002540:Cerebral Cortex; D051379:Mice; D010812:Physical Stimulation; D012867:Skin; D018038:Sodium Selenite; D013569:Synapses; D014738:Vibrissae; D015032:Zinc | Neuroscience | 2,005 | D018038:Sodium Selenite; D015032:Zinc |
Chemical composition and biological activities of Iranian Achillea wilhelmsii L. essential oil: a high effectiveness against Candida spp. and Escherichia strains. | In the case of Achillea wilhelmsii, 30 compounds were identified representing 94.48% of the total oil with a yield of 0.82% w/w. The major constituents of the oil were described as α-thujene (6.11%), α-pinene (5.11%), sabinene (5.23%), p-cymene (7%), 1,8-cineole (6%), linalool (10%), camphor (8.43%), thymol (18.98%) an... | 10.1080/14786419.2014.953949 | 25,209,950 | D031162:Achillea; D000890:Anti-Infective Agents; D000975:Antioxidants; D002176:Candida albicans; D004926:Escherichia coli; D007492:Iran; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile; D010938:Plant Oils | Natural product research | 2,015 | D000890:Anti-Infective Agents; D000975:Antioxidants; D009822:Oils, Volatile; D010938:Plant Oils |
Influence of stroke and bleeding risk on prescribing of oral anticoagulants in older inpatients; has the availability of direct oral anticoagulants changed prescribing? | BACKGROUND
Little is known about changes in prescribing practices in Australia since the introduction of the direct oral anticoagulants (DOACs). Our objective was to examine if the availability of DOACs has coincided with a change in prescribing of oral anticoagulants in older hospital inpatients with regard to risk fa... | 10.1177/2042098617747835 | 29,387,336 | Therapeutic advances in drug safety | 2,018 | ||
Comparative sensitivity to adenosine of paired-pulse inhibition and single field potentials in the rat hippocampus. | If excitatory terminals onto inhibitory interneurones were more sensitive to adenosine than excitatory terminals onto pyramidal cells in the hippocampus it might explain the effect of adenosine to decrease paired-pulse inhibition and account for reported excitatory effects of low concentrations of adenosine. We have co... | 10.1016/0304-3940(96)12605-7 | 8,734,912 | D000241:Adenosine; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D005071:Evoked Potentials; D006624:Hippocampus; D066298:In Vitro Techniques; D008297:Male; D008839:Microelectrodes; D017966:Pyramidal Cells; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors | Neuroscience letters | 1,996 | D000241:Adenosine |
Stereotypic behavioral response of rat fetuses to acute hypoxia is altered by maternal alcohol consumption. | Transient compression of the umbilical cord has been implicated as a potential cause of unexplained brain damage and/or fetal death. We induced acute fetal hypoxia by compressing the umbilical cord of the fetal rat with a microvascular clamp. Direct observation of fetal behavior immediately after cord compression ident... | 10.1016/s0002-9378(87)80100-x | 3,674,174 | D000208:Acute Disease; D000222:Adaptation, Physiological; D000428:Alcohol Drinking; D000818:Animals; D003250:Constriction; D005260:Female; D005311:Fetal Hypoxia; D005333:Fetus; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013239:Stereotyped Behavior; D013997:Time Factors; D014470:Umbilical Cord | American journal of obstetrics and gynecology | 1,987 | |
Pressure-sensitive adhesives for transdermal drug delivery systems. | Adhesives are a critical component in transdermal drug delivery (TDD) devices. In addition to the usual requirements of functional adhesive properties, adhesives for TDD applications must have good biocompatibility with the skin, chemical compatibility with the drug, various components of the formulation, and provide c... | 10.1016/s1461-5347(99)00119-4 | 10,234,208 | Pharmaceutical science & technology today | 1,999 | ||
Influence of climatic factors on dynamics of questing Ixodes ricinus ticks in Slovenia. | Ixodes ricinus is a vector of pathogens that cause many diseases in Europe and Slovenia: tick-borne encephalitis (TBE), anaplasmosis, borreliosis, babesiosis and others. The risk for contracting these diseases depends strongly on the density of the infected questing ticks and many studies have investigated tick populat... | 10.1016/j.vetpar.2009.06.001 | 19,560,275 | D000818:Animals; D002980:Climate; D005247:Feeding Behavior; D057232:Global Warming; D018884:Ixodes; D007814:Larva; D009758:Nymph; D012621:Seasons; D017524:Slovenia; D013997:Time Factors | Veterinary parasitology | 2,009 | |
Online brain attenuation correction in PET: towards a fully automated data handling in a clinical environment. | We have improved the calculation of the brain attenuation correction in positron emission tomography (PET) and set up a procedure which allows the clinician to get a fully corrected image in a single reconstruction step, without human intervention. By using a general object description scheme based on polygonal contour... | 10.1007/BF00631762 | 2,583,198 | D000328:Adult; D001921:Brain; D001330:Electronic Data Processing; D006801:Humans; D014055:Tomography, Emission-Computed | European journal of nuclear medicine | 1,989 | |
EST-derived microsatellites from Actinidia species and their potential for mapping. | To increase the speed and reduce the cost of constructing a genetic map of Actinidia species (kiwifruit), for use in both breeding and functional genomics programmes, we sampled microsatellites from expressed sequence tags (ESTs) to evaluate their frequency of occurrence and level of polymorphism. Perfect dinucleotide ... | 10.1007/s00122-003-1517-4 | 15,067,386 | D029042:Actinidia; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D017931:DNA Primers; D020224:Expressed Sequence Tags; D005843:Geography; D008126:Lod Score; D018895:Microsatellite Repeats | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik | 2,004 | D017931:DNA Primers |
The relationship between species richness and evenness: a meta-analysis of studies across aquatic ecosystems. | Biological diversity comprises both species richness, i.e., the number of species in a community, and evenness, measuring how similar species are in their abundances. The relationship between species richness and evenness (RRE) across communities remains, however, a controversial issue in ecology because no consistent ... | 10.1007/s00442-011-2236-1 | 22,210,185 | D059001:Aquatic Organisms; D044822:Biodiversity; D049628:Body Size; D020387:Food Chain; D005843:Geography | Oecologia | 2,012 | |
Designing a user interface and computer screens for instruction: some considerations. | Computer-assisted instruction and interactive videodisc are being used more often in allied health sciences education and medical training. Because computer graphics screens can enhance both legibility and readability, an effective computer interface for instruction is basic to the design and development of both. This ... | 1,624,476 | D003116:Color; D003196:Computer Graphics; D003194:Computer-Assisted Instruction; D003626:Data Display; D006801:Humans; D014584:User-Computer Interface; D014742:Videodisc Recording | The Journal of biocommunication | 1,992 | ||
Mechanical ventilation in patients with end-stage idiopathic pulmonary fibrosis. | BACKGROUND
Acute respiratory failure (ARF) occurring during idiopathic pulmonary fibrosis (IPF) is associated with a poor prognosis. In this subset of individuals, mechanical ventilation (MV) may be required.
OBJECTIVES
We analysed the characteristics of a group of IPF patients undergoing MV for ARF in order to give ... | 10.1159/000225932 | 19,546,508 | D000368:Aged; D003422:Critical Care; D005260:Female; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency; D012189:Retrospective Studies; D012384:Rome | Respiration; international review of thoracic diseases | 2,010 | |
Detection of Merkel cell polyomavirus in oral samples of renal transplant recipients without Merkel cell carcinoma. | Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine cancer, with approximately 80% of cases associated with Merkel cell polyomavirus (MCPyV). The lack of information concerning its occurrence in non-MCC immunosuppressed populations led to the investigation of MCPyV DNA in saliva and oral biopsies from 6... | 10.1002/jmv.23687 | 23,852,888 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003587:Cytomegalovirus; D005260:Female; D015654:Herpesvirus 6, Human; D016199:Herpesvirus 7, Human; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation; D008297:Male; D059965:Merkel cell polyomavirus;... | Journal of medical virology | 2,013 | |
Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH). | Platensimycin and platencin were successively discovered from the strain Streptomyces platensis through systematic screening. These natural products have been defined as promising agents for fighting multidrug resistance in bacteria by targeting type II fatty acid synthesis with slightly different mechanisms. Bioactivi... | 10.3390/molecules200916127 | 26,404,223 | D000218:Adamantane; D062365:Aminobenzoates; D000627:Aminophenols; D000813:Anilides; D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D024881:Drug Resistance, Bacterial; D054889:Fatty Acid Synthase, Type II; D015394:Molecular Structure; D011083:Polycyclic Compounds; D013302:Streptomyces | Molecules (Basel, Switzerland) | 2,015 | D062365:Aminobenzoates; D000627:Aminophenols; D000813:Anilides; D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D011083:Polycyclic Compounds; D054889:Fatty Acid Synthase, Type II; D000218:Adamantane; C510909:platensimycin; C520340:platencin |
Bilateral Dacryoadenitis and Central Nervous System Involvement in a Child With Kimura Disease. | Kimura's disease (KD) is a systemic inflammatory condition characterized by lymphadenopathy and subcutaneous nodules in the head and neck region. The lesions have a distinctive histopathological pattern formed by follicular hyperplasia, eosinophilic infiltrates, fibrosis, and vessel proliferation. The disease may occur... | 10.1097/IOP.0000000000002150 | 35,797,672 | D000796:Angiolymphoid Hyperplasia with Eosinophilia; D002490:Central Nervous System; D002648:Child; D003607:Dacryocystitis; D005260:Female; D006801:Humans; D000082242:Kimura Disease; D000072281:Lymphadenopathy; D008297:Male | Ophthalmic plastic and reconstructive surgery | 2,022 | |
Study protocol: brief intervention for medication overuse headache--a double-blinded cluster randomised parallel controlled trial in primary care. | BACKGROUND
Chronic headache (headache ≥ 15 days/month for at least 3 months) affects 2-5% of the general population. Medication overuse contributes to the problem. Medication-overuse headache (MOH) can be identified by using the Severity of Dependence Scale (SDS). A "brief intervention" scheme (BI) has previously been ... | 10.1186/1471-2377-12-70 | 22,883,540 | D000700:Analgesics; D016000:Cluster Analysis; D015897:Comorbidity; D004311:Double-Blind Method; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D051271:Headache Disorders, Secondary; D006801:Humans; D008297:Male; D009664:Norway; D015995:Prevalence; D011320:Primary Health Care; D016896:Treatment... | BMC neurology | 2,012 | D000700:Analgesics |
Characteristics and outcomes of chronic obstructive pulmonary disease in never smokers in Denmark: a prospective population study. | BACKGROUND
A substantial proportion of patients with chronic obstructive pulmonary disease (COPD) have never smoked. We tested the hypothesis that, in individuals with COPD, never smokers have different characteristics and less severe outcomes of the disease than smokers do.
METHODS
We included individuals from the C... | 24,461,615 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003718:Denmark; D004417:Dyspnea; D005541:Forced Expiratory Volume; D006760:Hospitalization; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive; D012307:Risk Factors; D012907:Smoking; D014797:Vital Capa... | The Lancet. Respiratory medicine | 2,013 | ||
Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance. | Acetylcholine (ACh) is a phylogenetically ancient molecule involved in cell-to-cell signaling in almost all life-forms on earth. Cholinergic components, including ACh, choline acetyltransferase, acetylcholinesterase, and muscarinic and nicotinic ACh receptors (mAChRs and nAChRs, respectively) have been identified in nu... | 10.1254/jphs.fm0070073 | 18,285,657 | D000109:Acetylcholine; D000650:Amnion; D000818:Animals; D002477:Cells; D005260:Female; D006801:Humans; D018482:Muscle, Skeletal; D010053:Ovary; D010920:Placenta; D013710:Tendons; D001743:Urinary Bladder | Journal of pharmacological sciences | 2,008 | D000109:Acetylcholine |
Insulin-like growth factor-I receptors in ovarian granulosa cells: effect of follicle size and hormones. | The objectives of the present studies were to determine if the numbers of IGF-I receptors in bovine granulosa cells differed with size of follicle and to determine if growth factors and hormones affected the number of IGF-I receptors in granulosa cells. Granulosa cells from small (1-5 mm) and large (> or = 8 mm) follic... | 10.1016/0303-7207(94)90099-x | 7,926,275 | D000818:Animals; D002417:Cattle; D002452:Cell Count; D002478:Cells, Cultured; D004815:Epidermal Growth Factor; D004958:Estradiol; D005260:Female; D016222:Fibroblast Growth Factor 2; D005640:Follicle Stimulating Hormone; D006107:Granulosa Cells; D006080:Ovarian Follicle; D011869:Radioligand Assay; D017526:Receptor, IGF ... | Molecular and cellular endocrinology | 1,994 | D016222:Fibroblast Growth Factor 2; D004958:Estradiol; D004815:Epidermal Growth Factor; D005640:Follicle Stimulating Hormone; D017526:Receptor, IGF Type 1 |
Trigeminal neuralgia due to Dandy-Walker syndrome. | Trigeminal neuralgia (TN) is a common pain in the orofacial region. Dandy-Walker syndrome (DWS) is a congenital malformation of the cerebellar and the fourth ventricle foramina atresia. Dandy-Walker syndrome is rarely found in patients with TN. This article presents a 36-year-old man with the symptoms of typical TN. Hi... | 10.1097/SCS.0b013e31828f2ef2 | 23,851,831 | D000328:Adult; D002531:Cerebellum; D002552:Cerebral Ventricles; D003616:Dandy-Walker Syndrome; D006801:Humans; D006849:Hydrocephalus; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D014277:Trigeminal Neuralgia | The Journal of craniofacial surgery | 2,013 | |
Putting the brakes on: abscisic acid as a central environmental regulator of stomatal development. | Stomata are produced by a controlled series of epidermal cell divisions. The molecular underpinnings of this process are becoming well understood, but mechanisms that determine plasticity of stomatal patterning to many exogenous and environmental cues remain less clear. Light quantity and quality, vapour pressure defic... | 10.1111/nph.12713 | 24,611,444 | D000040:Abscisic Acid; D002244:Carbon; D004777:Environment; D010788:Photosynthesis; D010937:Plant Growth Regulators; D054046:Plant Stomata; D018526:Plant Transpiration; D010944:Plants; D015398:Signal Transduction; D013312:Stress, Physiological | The New phytologist | 2,014 | D010937:Plant Growth Regulators; D000040:Abscisic Acid; D002244:Carbon |
Diagnostic nomogram for gallbladder wall thickening mimicking malignancy: using contrast-enhanced ultrasonography or multi-detector computed tomography? | OBJECTIVES
To establish a diagnostic nomogram using contrast-enhanced ultrasonography (CEUS) in gallbladder wall thickening mimicking malignancy and compare with multi-detector computed tomography (MDCT).
METHODS
Seventy-two patients with gallbladder wall thickening on B-mode ultrasonography (BUS) were examined by CE... | 10.1007/s00261-017-1162-z | 28,447,109 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D005705:Gallbladder Diseases; D005706:Gallbladder Neoplasms; D006801:Humans; D008297:Male; D008875:Middle Aged; D049451:Nomograms; D012189:Retrospective Studies; D014057:Tomography, X-Ray Com... | Abdominal radiology (New York) | 2,017 | D003287:Contrast Media |
The Feasibility of a Sensate Profunda Artery Perforator Flap in Autologous Breast Reconstruction: An Anatomic Study for Clinical Application. | BACKGROUND
The profunda artery perforator (PAP) flap has been demonstrated to be an effective method of autologous breast reconstruction, particularly when the abdominal donor site is contraindicated. However, there are no current reports regarding the use of a sensate PAP flap in this type of reconstruction. The objec... | 10.1097/SAP.0000000000002275 | 32,028,466 | D001158:Arteries; D005240:Feasibility Studies; D006801:Humans; D016462:Mammaplasty; D061525:Perforator Flap; D013848:Thigh | Annals of plastic surgery | 2,020 | |
Cross-sectional study estimating the psychosocial impact of genital warts and other anogenital diseases in South Korea. | OBJECTIVES
To estimate self-reported human papillomavirus (HPV) disease-related psychosocial impact among male and female patients in South Korea.
DESIGN
In this multicentre cross-sectional study, psychosocial impacts were estimated using a one-time survey capturing HPV Impact Profile (HIP) results, CuestionarioEspec... | 10.1136/bmjopen-2018-025035 | 30,898,815 | D000328:Adult; D001007:Anxiety; D017281:Cost of Illness; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections; D017060:Patient Satisfaction; D011788:Quality of Life; D056910:Republic of Korea; D013315:Stress, Psychol... | BMJ open | 2,019 | |
Cutoff points of adiposity anthropometric indices for low muscle mass screening in middle-aged and older healthy women. | BACKGROUND
The reduction of female sex hormones causes changes in the contractile properties of muscles as well as infiltration of fat in the muscle tissue. This results in a consequent decline in muscle strength. These changes are related to higher levels of functional impairment and physical disability. In this sense... | 10.1186/s12891-021-04532-x | 34,416,881 | D050154:Adiposity; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D009132:Muscles; D009765:Obesity | BMC musculoskeletal disorders | 2,021 | |
Discovery of MAO-B inhibitors - present status and future directions part I: oxygen heterocycles and analogs. | Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The role of monoamine oxidase (MAO) inhibitors has expanded in the PD treatment. The present review will summarize the current structureactivity relationship information available on MAOs inhibitors of unrelated families of compounds of oxy... | 10.2174/138955712802762301 | 22,420,569 | D000818:Animals; D047188:Chalcones; D002867:Chromones; D003374:Coumarins; D006801:Humans; D008995:Monoamine Oxidase; D008996:Monoamine Oxidase Inhibitors; D010300:Parkinson Disease | Mini reviews in medicinal chemistry | 2,012 | D047188:Chalcones; D002867:Chromones; D003374:Coumarins; D008996:Monoamine Oxidase Inhibitors; D008995:Monoamine Oxidase |
Epigenetic analysis in placentas from sickle cell disease patients reveals a hypermethylation profile. | Pregnancy in Sickle Cell Disease (SCD) women is associated to increased risk of clinical and obstetrical complications. Placentas from SCD pregnancies can present increased abnormal findings, which may lead to placental insufficiency, favoring adverse perinatal outcome. These placental abnormalities are well known and ... | 10.1371/journal.pone.0274762 | 36,129,958 | D000755:Anemia, Sickle Cell; D044127:Epigenesis, Genetic; D005260:Female; D006450:Hemoglobin SC Disease; D006451:Hemoglobin, Sickle; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta; D011247:Pregnancy; D011509:Proteoglycans | PloS one | 2,022 | D006451:Hemoglobin, Sickle; D011509:Proteoglycans; C504369:SPOCK1 protein, human |
Incidence of HIV and HTLV-1 infection among sexually transmitted disease clinic attenders in Jamaica. | Of 970 sexually transmitted disease (STD) patients enrolled at the Comprehensive Health Centre, Kingston, Jamaica, between November 1990 and January 1991, 710 (73%, 333 men and 377 women) were reexamined between January 1992 and July 1993 to estimate the incidence of HIV and HTLV-I infection and to identify risk factor... | 10.1097/00042560-199707010-00007 | 9,257,658 | D000328:Adult; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006678:HIV; D015483:HIV Antibodies; D015658:HIV Infections; D015481:HTLV-I Antibodies; D015490:HTLV-I Infections; D015368:Human T-lymphotropic virus 1; D006801:Humans; D015994:Incidence; D007563:Jamaica; D008297:Male; ... | Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association | 1,997 | D015483:HIV Antibodies; D015481:HTLV-I Antibodies |
The Relationship between Cellphone Usage on the Physical and Mental Wellbeing of University Students: A Cross-Sectional Study. | (1) Background: The study aims to examine the use of cell phones on physical and mental health status and their impact on personality among university students. (2) Methods: A cross-sectional study was conducted using a semi-structured questionnaire. The association of physical and mental health variables with the demo... | 10.3390/ijerph19159352 | 35,954,709 | D000328:Adult; D040421:Cell Phone; D003430:Cross-Sectional Studies; D006801:Humans; D008603:Mental Health; D019547:Neck Pain; D013334:Students; D014495:Universities; D015430:Weight Gain; D055815:Young Adult | International journal of environmental research and public health | 2,022 | |
Chronic administration of ketamine mimics the perturbed sense of body ownership associated with schizophrenia. | RATIONALE
Subanaesthetic ketamine infusion in healthy volunteers induces experiences redolent of early psychosis, including changes in the experience of one's own body. It is not clear, however, whether repeated self-administration of ketamine has a sustained effect on body representation that is comparable to that fou... | 10.1007/s00213-014-3782-0 | 25,404,087 | D000328:Adult; D000778:Anesthetics, Dissociative; D001828:Body Image; D005260:Female; D006801:Humans; D007088:Illusions; D007649:Ketamine; D008297:Male; D011618:Psychotic Disorders; D012565:Schizophrenic Psychology; D012649:Self Concept; D055815:Young Adult | Psychopharmacology | 2,015 | D000778:Anesthetics, Dissociative; D007649:Ketamine |
Neural mechanisms underlying the higher levels of subjective well-being in extraverts: pleasant bias and unpleasant resistance. | The present study investigated the neural mechanisms that underlie the higher levels of subjective well-being in extraverts. The impact of extraversion on the human sensitivity to pleasant and unpleasant pictures of diverse emotional intensities was examined. We recorded event-related potentials (ERPs) for highly posit... | 10.3758/s13415-011-0064-8 | 21,987,094 | D000328:Adult; D015982:Bias; D001921:Brain; D001931:Brain Mapping; D004569:Electroencephalography; D004644:Emotions; D005074:Evoked Potentials, Visual; D005120:Extraversion, Psychological; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D011930:Reaction Time; ... | Cognitive, affective & behavioral neuroscience | 2,012 | |
Ile to Val polymorphism at codon 655 of HER-2 gene and breast cancer risk in Iranian women. | The earlier reports on the association between the Ile to Val polymorphism at codon 655 of HER-2 and susceptibility to breast cancer has not been found to hold true for all ethnic populations. Two hundred and four cases and 138 controls were collected to investigate the association of HER-2 Ile655Val polymorphism with ... | 10.1016/j.canlet.2004.04.007 | 15,374,636 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms; D044584:Carcinoma, Ductal; D016022:Case-Control Studies; D003062:Codon; D005260:Female; D005787:Gene Frequency; D018734:Genes, erbB-2; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007492:Iran; D008875:Midd... | Cancer letters | 2,004 | D003062:Codon |
[Developing the control criterion for continuous culture of microorganisms]. | A short survey and critical analysis of previously proposed criteria for growth control of populations of microorganisms in the chemostat are presented. Based on the analysis of a mathematical model of the steady-state of a microbial population in the chemostat, an adequate control criterion is suggested, along with a ... | 15,835,773 | D000465:Algorithms; D001419:Bacteria; D001431:Bacteriological Techniques; D018533:Biomass; D003470:Culture Media; D017753:Ecosystem; D008954:Models, Biological | Mikrobiologiia | 2,005 | D003470:Culture Media | |
A blueprint for real-time functional mapping via human intracranial recordings. | BACKGROUND
The surgical treatment of patients with intractable epilepsy is preceded by a pre-surgical evaluation period during which intracranial EEG recordings are performed to identify the epileptogenic network and provide a functional map of eloquent cerebral areas that need to be spared to minimize the risk of post... | 10.1371/journal.pone.0001094 | 17,971,857 | D001921:Brain; D001931:Brain Mapping; D002540:Cerebral Cortex; D004558:Electric Stimulation; D004569:Electroencephalography; D004827:Epilepsy; D005072:Evoked Potentials, Auditory; D006801:Humans; D007802:Language; D008954:Models, Biological; D009415:Nerve Net; D009991:Oscillometry; D012984:Software; D013702:Temporal Lo... | PloS one | 2,007 | |
Corticosteroid-binding globulin (CBG) production by hepatic and extra-hepatic sites in the ovine fetus; effects of CBG on glucocorticoid negative feedback on pituitary cells in vitro. | Plasma cortisol levels increase in fetal sheep during late gestation and this is associated with an increase in plasma corticosteroid-binding globulin (CBG) concentrations. However, the relative tissue sources of plasma CBG, the ontogeny of its biosynthesis and glycoform composition have not been established in the ovi... | 10.1677/joe.0.1460121 | 7,561,608 | D000324:Adrenocorticotropic Hormone; D000818:Animals; D002478:Cells, Cultured; D003346:Corticotropin-Releasing Hormone; D005246:Feedback; D005312:Fetal Blood; D006854:Hydrocortisone; D008099:Liver; D010902:Pituitary Gland; D012756:Sheep; D014156:Transcortin | The Journal of endocrinology | 1,995 | D000324:Adrenocorticotropic Hormone; D014156:Transcortin; D003346:Corticotropin-Releasing Hormone; D006854:Hydrocortisone |
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress. | Chronic pain is the predominant problem for rheumatoid arthritis patients, and negatively affects quality of life. Arthritis pain management remains largely inadequate, and developing new treatment strategies are urgently needed. Spinal inflammation and oxidative stress contribute to arthritis pain and represent ideal ... | 10.1177/17448069221146398 | 36,474,308 | D000818:Animals; D051379:Mice; D055372:AMP-Activated Protein Kinases; D001169:Arthritis, Experimental; D001172:Arthritis, Rheumatoid; D059350:Chronic Pain; D004642:Emodin; D007249:Inflammation; D051267:NF-E2-Related Factor 2; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D018384:Oxidative Stress; D013482:Su... | Molecular pain | 2,022 | D055372:AMP-Activated Protein Kinases; D004642:Emodin; D051267:NF-E2-Related Factor 2; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D013482:Superoxide Dismutase; D014409:Tumor Necrosis Factor-alpha |
Competing opinions and stubborness: Connecting models to data. | We introduce a general contagionlike model for competing opinions that includes dynamic resistance to alternative opinions. We show that this model can describe candidate vote distributions, spatial vote correlations, and a slow approach to opinion consensus with sensible parameter values. These empirical properties of... | 10.1103/PhysRevE.93.032305 | 27,078,364 | Physical review. E | 2,016 | ||
Recent advances in magnesium assessment: From single selective sensors to multisensory approach. | The development of efficient analytical procedures for the selective detection of magnesium is an important analytical task, since this element is one of the most abundant metals in cells and plays an essential role in a plenty of cellular processes. Magnesium misbalance has been related to several pathologies and dise... | 10.1016/j.talanta.2017.11.019 | 29,310,257 | Talanta | 2,018 | ||
Influence of hypothyroidism induced at prepuberty on epididymal lipids and the number and motility of spermatozoa in rats. | Fifteen prepubertal male rats (age 30 days) were divided into three groups of five each: Group 1, hypothyroid (Tx)--rats were thyroidectomized at day 30; Group 2, T4 (L-thyroxine) replacement therapy (Tx+T4)--rats were thyroidectomized at day 30 and treated daily i.m. with T4 (6 micrograms/100 g body weight/day) for 30... | 10.1111/j.1365-2605.1994.tb01252.x | 7,698,852 | D000818:Animals; D002908:Chronic Disease; D004822:Epididymis; D007037:Hypothyroidism; D050356:Lipid Metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012741:Sexual Maturation; D013076:Sperm Count; D013081:Sperm Motility; D013739:Testosterone; D013974:Thyroxine; D014284:Triiodothyronine | International journal of andrology | 1,994 | D014284:Triiodothyronine; D013739:Testosterone; D013974:Thyroxine |
Vimentin-crossreactive antibodies induce cell death in primary cultures of embryonic spinal cord. | Sera from guinea pigs inoculated with spinal cord gray matter were cytotoxic for embryonic day 14 (ED14) primary spinal cord cell cultures. All cell types including astroglia and neurons were affected. Immunoglobulin (IgG) from inoculated animals and biologically active complement proteins were both identified as neces... | 10.1016/0165-5728(93)90207-f | 8,423,205 | D000327:Adsorption; D000818:Animals; D000906:Antibodies; D001253:Astrocytes; D001327:Autoimmune Diseases; D001927:Brain Diseases; D016923:Cell Death; D002470:Cell Survival; D002478:Cells, Cultured; D002795:Choline O-Acetyltransferase; D003165:Complement System Proteins; D003429:Cross Reactions; D003598:Cytoskeletal Pro... | Journal of neuroimmunology | 1,993 | D000906:Antibodies; D003598:Cytoskeletal Proteins; D005904:Glial Fibrillary Acidic Protein; D007136:Immunoglobulins; D014746:Vimentin; D003165:Complement System Proteins; D002795:Choline O-Acetyltransferase |
A randomized trial with steroids and antithymocyte globulins comparing cyclosporine/azathioprine versus tacrolimus/mycophenolate mofetil (CATM2) in renal transplantation. | BACKGROUND
The best immunosuppressive regimen in benefit-risk ratio in renal transplantation is debated. Nowadays, tacrolimus (Tac) and mycophenolate mofetil (MMF) are considered more efficient than cyclosporine A (CsA) and MMF, but recent studies have challenged this assumption.
METHODS
We conducted a monocentric, p... | 10.1097/TP.0b013e31824215b7 | 22,228,415 | D000328:Adult; D000961:Antilymphocyte Serum; D001379:Azathioprine; D002318:Cardiovascular Diseases; D015331:Cohort Studies; D016572:Cyclosporine; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006084:Graft Rejection; D006085:Graft Survival; D006801:Hum... | Transplantation | 2,012 | D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents; D013256:Steroids; D016572:Cyclosporine; D009173:Mycophenolic Acid; D001379:Azathioprine; D011241:Prednisone; D016559:Tacrolimus |
One-item susceptibility measure predicts waterpipe and little cigar/cigarillo uptake in a national sample of adolescents and young adults in the United States. | INTRODUCTION
Adolescents and young adults in the United States (US) are increasingly using non-cigarette tobacco products such as waterpipe (WP) and little cigars/cigarillos (LCC). One way to predict which non-user adolescents and young adults are most likely to use these products is through measuring their susceptibil... | 10.18332/tpc/108554 | 32,411,881 | Tobacco prevention & cessation | 2,019 | ||
Inhibition of Autograft Bone Resorption by Antibone Resorptive Agents After Spinal Reconstruction Surgery for Extensive Cervical Chondrosarcoma: A Case Report with a 10-Year Follow-Up. | BACKGROUND
For the surgical treatment of spinal malignant tumor, spinal reconstruction with bone graft and instrumentation is necessary after tumor resection, but postoperative complications, including grafted bone resorption, may arise.
CASE DESCRIPTION
A 42-year-old Asian woman presented with neck pain, tumorous ma... | 10.1016/j.wneu.2020.07.012 | 32,659,359 | D000328:Adult; D064592:Autografts; D001862:Bone Resorption; D016025:Bone Transplantation; D002574:Cervical Vertebrae; D002813:Chondrosarcoma; D004164:Diphosphonates; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007093:Imidazoles; D019651:Plastic Surgery Procedures; D013125:Spinal Neoplasms; D013997:Time ... | World neurosurgery | 2,020 | D004164:Diphosphonates; D007093:Imidazoles; C087958:YM 529 |
Occupational exposure to lead and lung cancer: results from two case-control studies in Montreal, Canada. | OBJECTIVES
We investigated the association between workplace lead exposure and lung cancer risk, separately for organic lead and for inorganic lead, from either engine emissions or from other sources.
METHODS
Two population-based case-control studies were carried out in Montreal (1979-1986 and 1996-2002) to investiga... | 10.1136/oemed-2012-100931 | 23,322,922 | D000368:Aged; D000395:Air Pollutants, Occupational; D002170:Canada; D016022:Case-Control Studies; D006801:Humans; D007407:Interviews as Topic; D007854:Lead; D007855:Lead Poisoning; D016015:Logistic Models; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D016273:Occupational Exp... | Occupational and environmental medicine | 2,013 | D000395:Air Pollutants, Occupational; D001335:Vehicle Emissions; D007854:Lead |
ERp29 inhibits tumorigenicity by suppressing epithelial mesenchymal transition in gastric cancer. | ERp29 is a novel endoplasmic reticulum (ER) protein that plays an important role in protein unfolding and secretion. Recently, it has been reported to be widely implicated in control of tumorigenesis in some tumors. However, the potential function of ERp29 in gastric cancer remains poorly understood. In this study, we ... | 10.18632/oncotarget.20225 | 29,108,263 | Oncotarget | 2,017 | ||
The diameter of single bundle, hamstring autograft does not significantly influence revision rate or clinical outcomes after anterior cruciate ligament reconstruction. | BACKGROUND
Anterior cruciate ligament (ACL) graft failure is a complication of ACL reconstruction (ALCR). Smaller autograft diameter may be a contributing factor. Our aim was to determine if hamstring autograft diameter influences graft rupture and patient-reported outcome scores.
METHODS
This study included 786 cons... | 10.1016/j.knee.2017.05.011 | 28,797,872 | D000293:Adolescent; D000328:Adult; D016118:Anterior Cruciate Ligament; D000070598:Anterior Cruciate Ligament Injuries; D059549:Anterior Cruciate Ligament Reconstruction; D064592:Autografts; D002648:Child; D005260:Female; D000070632:Hamstring Tendons; D006801:Humans; D008297:Male; D000071066:Patient Reported Outcome Mea... | The Knee | 2,017 | |
The role of scission in the perception of color and opacity. | Recent work has shown that the decomposition of textures into a layered representation can induce striking percepts of inhomogeneous transparency and modulate the perceived lightness of achromatic textures (B. L. Anderson & J. Winawer, 2005, 2008). It was argued that two photo-geometric principles of perceptual organiz... | 20,616,125 | D003118:Color Perception; D055253:Color Vision; D006801:Humans; D008029:Lighting; D010364:Pattern Recognition, Visual; D010470:Perceptual Masking | Journal of vision | 2,010 | ||
The Value of Circulating Tumor Cells in the Prognosis and Treatment of Pancreatic Cancer. | In the past few decades, tumor diagnosis and treatment theory have developed in a variety of directions. The number of people dying from pancreatic cancer increases while the mortality rate of other common tumors decreases. Traditional imaging methods show the boundaries of pancreatic tumor, but they are not sufficient... | 10.3389/fonc.2022.933645 | 35,860,591 | Frontiers in oncology | 2,022 | ||
Harmonic Noise-Tolerant ZNN for Dynamic Matrix Pseudoinversion and Its Application to Robot Manipulator. | As we know, harmonic noises widely exist in industrial fields and have a crucial impact on the computational accuracy of the zeroing neural network (ZNN) model. For tackling this issue, by combining the dynamics of harmonic signals, two harmonic noise-tolerant ZNN (HNTZNN) models are designed for the dynamic matrix pse... | 10.3389/fnbot.2022.928636 | 35,770,275 | Frontiers in neurorobotics | 2,022 | ||
Mesoporous Carbon Supported Rh Nanoparticle Catalysts for the Production of C2+ Alcohol from Syngas. | Uniform rhodium nanoparticles (NP) with three different particle sizes (1.9, 2.4, and 3.6 nm) were prepared via a polyol method with rhodium (III) acetylacetonate, poly(vinylpyrrolidone) with different concentrations of sodium citrate. The prepared Rh nanoparticles were impregnated into the ordered mesoporous carbon su... | 10.1166/jnn.2016.11990 | 27,433,718 | D000438:Alcohols; D002244:Carbon; D002384:Catalysis; D016062:Porosity; D012238:Rhodium | Journal of nanoscience and nanotechnology | 2,016 | D000438:Alcohols; D002244:Carbon; D012238:Rhodium |
Roles of distinct glutamate receptors in induction of anti-Hebbian long-term potentiation. | Many glutamatergic synapses on interneurons involved in feedback inhibition in the CA1 region of the hippocampus exhibit an unusual form of long-term potentiation (LTP) that is induced only if presynaptic glutamate release occurs when the postsynaptic membrane potential is relatively hyperpolarized. We have named this ... | 10.1113/jphysiol.2007.148064 | 18,187,472 | D000818:Animals; D020013:Calcium Signaling; D005246:Feedback; D006624:Hippocampus; D017774:Long-Term Potentiation; D008959:Models, Neurological; D009433:Neural Inhibition; D009474:Neurons; D017470:Receptors, Glutamate; D009435:Synaptic Transmission | The Journal of physiology | 2,008 | D017470:Receptors, Glutamate |
Troglitazone has a scavenging effect on reactive oxygen species. | Troglitazone (CS-045), a newly developed antidiabetic thiazolidinedione that enhances insulin sensitivity, is similar in structure to several antioxidants, including alpha-tocopherol and probucol. The in vitro antioxidant activity of troglitazone has been demonstrated in alloxan-induced hyperlipoperoxidemic and hyperli... | 10.1006/bbrc.1997.6512 | 9,196,046 | D000975:Antioxidants; D002839:Chromans; D003574:Cytochrome c Group; D004121:Dimethyl Sulfoxide; D004578:Electron Spin Resonance Spectroscopy; D016166:Free Radical Scavengers; D006801:Humans; D006861:Hydrogen Peroxide; D007501:Iron; D015394:Molecular Structure; D009504:Neutrophils; D000077205:Pioglitazone; D017382:React... | Biochemical and biophysical research communications | 1,997 | D000975:Antioxidants; D002839:Chromans; D003574:Cytochrome c Group; C045076:Fenton's reagent; D016166:Free Radical Scavengers; D017382:Reactive Oxygen Species; D013113:Spin Labels; D013844:Thiazoles; D045162:Thiazolidinediones; D014970:Xanthines; D014810:Vitamin E; D019820:Xanthine; D006861:Hydrogen Peroxide; D007501:I... |
Partial androgen insensitivity as a cause of genital maldevelopment. | A newborn with ambiguous genitalia appeared to have male pseudohermaphroditism caused by partial insensitivity to androgens associated with a subnormal level of androgen receptors in cultured genital skin fibroblasts. This hitherto infrequently diagnosed condition has genetical and prognostic implications regarding fer... | 6,544,308 | D000728:Androgens; D002478:Cells, Cultured; D012734:Disorders of Sex Development; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D011944:Receptors, Androgen; D012611:Scrotum; D012867:Skin | Helvetica paediatrica acta | 1,984 | D000728:Androgens; D011944:Receptors, Androgen | |
Crystal structure of flufenoxuron: a benzoyl-urea pesticide. | The title compound, C21H11ClF6N2O3 (systematic name: 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-(2,6-di-fluoro-benzo-yl)urea), is a benzoyl-urea pesticide. The dihedral angles between the central fluoro-benzene ring and the terminal di-fluoro-phenyl ring and chloro-phenyl ring system are 62.15 (5) and... | 10.1107/S1600536814020649 | 25,484,700 | Acta crystallographica. Section E, Structure reports online | 2,014 | ||
Transformation of mammalian cells with an amplifiable dominant-acting gene. | We have transferred a mutant hamster gene coding for an altered dihydrofolate reductase to wild-type cultured mouse cells by using total genomic DNA from methotrexate-resistant Chinese hamster ovary A29 cells as donor. By demonstrating the presence of hamster gene sequences in transformants we have provided direct evid... | 10.1073/pnas.77.6.3567 | 6,251,468 | D000818:Animals; D002460:Cell Line; D002999:Clone Cells; D006224:Cricetinae; D003412:Cricetulus; D004926:Escherichia coli; D005347:Fibroblasts; D005799:Genes, Dominant; D005822:Genetic Vectors; D051379:Mice; D021141:Nucleic Acid Amplification Techniques; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D013762:Tet... | Proceedings of the National Academy of Sciences of the United States of America | 1,980 | D013762:Tetrahydrofolate Dehydrogenase |
Elucidation of a carboxylate O-methyltransferase NcmP in nocamycin biosynthetic pathway. | Nocamycins belong to the tetramic acid family natural products and show potent antimicrobial activity. Recently, the biosynthetic gene cluster of nocamycin was identified from the rare actinomycete Saccharothrix syringae and an S-adenosylmethionine (SAM) dependent methyltransferase gene NcmP was found to be located wit... | 10.1016/j.bmcl.2017.08.010 | 28,818,448 | D000192:Actinomycetales; D000900:Anti-Bacterial Agents; D001407:Bacillus; D004305:Dose-Response Relationship, Drug; D013293:Enterococcus faecalis; D008780:Methyltransferases; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus; D015394:Molecular Structure; D009930:Organic Chemicals; D061065:Polyketides; D01... | Bioorganic & medicinal chemistry letters | 2,017 | D000900:Anti-Bacterial Agents; D009930:Organic Chemicals; D061065:Polyketides; C015397:nocamycin; D008780:Methyltransferases |
Feasibility, acceptability, and effectiveness of an electronic sensor bed/chair alarm in reducing falls in patients with cognitive impairment in a subacute ward. | Falls from bed are common in subacute hospital settings, particularly for patients with cognitive impairment. This repeated measures, single cohort study in 1 subacute ward evaluated effectiveness of an electronic sensor alarm in reducing falls in patients (n = 34) with cognitive impairment. Nursing staff feedback (foc... | 10.1097/NCQ.0000000000000054 | 24,487,696 | D000058:Accidental Falls; D001513:Beds; D003072:Cognition Disorders; D015331:Cohort Studies; D004582:Electronics, Medical; D005240:Feasibility Studies; D005260:Female; D017144:Focus Groups; D006761:Hospitals; D006801:Humans; D007374:Interior Design and Furnishings; D008297:Male; D009740:Nursing Staff | Journal of nursing care quality | 2,014 | |
Books on Prescription - community-based health initiative to increase access to mental health treatment: an evaluation. | OBJECTIVE
To evaluate the implementation of a regional Books on Prescription (BoP) programme.
METHODS
Seven data collection pathways were used to provide indicators of program implementation, utilisation, acceptability and reach.
RESULTS
BoP is seen by prescribers, librarians and consumers as a valuable mental heal... | 10.1111/1753-6405.12507 | 27,027,774 | D000293:Adolescent; D000328:Adult; D001291:Attitude of Health Personnel; D001638:Bibliotherapy; D001877:Books; D005260:Female; D057220:Health Literacy; D006297:Health Services Accessibility; D006801:Humans; D008297:Male; D001523:Mental Disorders; D008603:Mental Health; D009520:New Zealand; D017060:Patient Satisfaction;... | Australian and New Zealand journal of public health | 2,016 | |
Adipsin Serum Concentrations and Adipose Tissue Expression in People with Obesity and Type 2 Diabetes. | (1) Adipsin is an adipokine that may link increased fat mass and adipose tissue dysfunction to obesity-related cardiometabolic diseases. Here, we investigated whether adipsin serum concentrations and adipose tissue (AT) adipsin mRNA expression are related to parameters of AT function, obesity and type 2 diabetes (T2D).... | 10.3390/ijms23042222 | 35,216,336 | D000273:Adipose Tissue; D000368:Aged; D001786:Blood Glucose; D015992:Body Mass Index; D011416:Complement Factor D; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D007328:Insulin; D050152:Intra-Abdominal Fat; D008297:Male; D008875:Middle Aged; D009765:Obesity; D055105:Waist Circumference | International journal of molecular sciences | 2,022 | D001786:Blood Glucose; D007328:Insulin; C493488:CFD protein, human; D011416:Complement Factor D |
A non-self-consistent tight-binding electronic structure potential in a polarized double-ζ basis set for all spd-block elements up to Z = 86. | Existing semiempirical molecular orbital methods suffer from the usually minimal atomic-orbital (AO) basis set used to simplify the calculations. Here, a completely new and consistently parameterized tight-binding electronic structure Hamiltonian evaluated in a deeply contracted, properly polarized valence double-zeta ... | 10.1063/5.0137838 | 37,003,744 | The Journal of chemical physics | 2,023 | ||
Semi-automated quantification of filopodial dynamics. | Cellular motility underlies critical physiological processes including embryogenesis, metastasis and wound healing. Nerve cells undergo cellular migration during development and also extend neuronal processes for long distances through a complex microenvironment to appropriately wire the nervous system. The growth cone... | 10.1016/j.jneumeth.2008.02.009 | 18,394,712 | D000465:Algorithms; D000818:Animals; D002465:Cell Movement; D002642:Chick Embryo; D003952:Diagnostic Imaging; D001330:Electronic Data Processing; D005727:Ganglia, Spinal; D009474:Neurons; D017711:Nonlinear Dynamics; D009924:Organ Culture Techniques; D011554:Pseudopodia; D013997:Time Factors | Journal of neuroscience methods | 2,008 | |
cCPE Fusion Proteins as Molecular Probes to Detect Claudins and Tight Junction Dysregulation in Gastrointestinal Cell Lines, Tissue Explants and Patient-Derived Organoids. | Claudins regulate paracellular permeability, contribute to epithelial polarization and are dysregulated during inflammation and carcinogenesis. Variants of the claudin-binding domain of Clostridium perfringens enterotoxin (cCPE) are highly sensitive protein ligands for generic detection of a broad spectrum of claudins.... | 10.3390/pharmaceutics15071980 | 37,514,167 | Pharmaceutics | 2,023 | ||
Immunologic methods for the detection of benzo[a]pyrene metabolites in urine. | Two monoclonal antibodies (10C10 and 4D5) have been developed from the spleen cells of Balb/c mice immunized with 6-aminobenzo[a]pyrene covalently coupled to bovine serum albumin. These antibodies have been used in an immunoassay for the detection of benzo[a]pyrene and its metabolites in mouse urine. The antibodies wer... | 10.1021/tx00016a006 | 2,133,077 | D000818:Animals; D000911:Antibodies, Monoclonal; D001564:Benzo(a)pyrene; D002845:Chromatography; D004247:DNA; D004797:Enzyme-Linked Immunosorbent Assay; D051379:Mice; D008807:Mice, Inbred BALB C | Chemical research in toxicology | 1,990 | D000911:Antibodies, Monoclonal; D001564:Benzo(a)pyrene; D004247:DNA |
Mitochondrial phylogeny of the Eurasian/African reed warbler complex (Acrocephalus, Aves). Disagreement between morphological and molecular evidence and cryptic divergence: A case for resurrecting Calamoherpe ambigua Brehm 1857. | A tree based on the mitochondrial cyt b gene for 278 samples from throughout the range of the Eurasian Reed Warbler Acrocephalus scirpaceus - African Reed Warbler A. baeticatus complex shows well-supported geographically structured divergence for eight distinct lineages. The phylogenetic structuring together with the c... | 27,233,439 | D000349:Africa; D000818:Animals; D001208:Asia; D045303:Cytochromes b; D004272:DNA, Mitochondrial; D003710:Demography; D005060:Europe; D050259:Genes, Mitochondrial; D014644:Genetic Variation; D005843:Geography; D015999:Multivariate Analysis; D010802:Phylogeny; D025341:Principal Component Analysis; D020308:Songbirds | Molecular phylogenetics and evolution | 2,016 | D004272:DNA, Mitochondrial; D045303:Cytochromes b | |
[Current events in fetal magnetic resonance]. | The challenge of fetal imaging is crucial in France because of the law allowing termination of pregnancy (TOP) until the end of pregnancy. Fetal MRI is an imaging tool always used after ultrasonography (US). Its indications are pertinent only in relation with a prenatal center. Fetal MRI raises parental anxiety to take... | 10.1016/j.arcped.2010.07.017 | 20,829,001 | D001921:Brain; D002552:Cerebral Ventricles; D003388:Cranial Fossa, Posterior; D005260:Female; D005333:Fetus; D006801:Humans; D007415:Intestinal Obstruction; D008279:Magnetic Resonance Imaging; D009369:Neoplasms; D011237:Predictive Value of Tests; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011704:Pyelonephritis; D0... | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie | 2,010 | |
Tumefactive demyelination and glioblastoma: a rare collision lesion. | OBJECTIVE
Inflammatory demyelination occasionally forms a solitary mass lesion clinically and radiographically indistinguishable from glioma, replete with enhancement and mass effect. Termed "tumefactive demyelination" it often prompts a brain biopsy.
DESIGN
We undertook neuroimaging and morphologic analysis of a uni... | 10.5414/np300201 | 21,726,504 | D001253:Astrocytes; D001706:Biopsy; D001932:Brain Neoplasms; D015897:Comorbidity; D003711:Demyelinating Diseases; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma; D006644:Histiocytes; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged | Clinical neuropathology | 2,011 | |
Tapping into the interplay of lexical and number knowledge using fast mapping: A longitudinal eye-tracking study with two-year-olds. | Language skills and mathematical competencies are argued to influence each other during development. While a relation between the development of vocabulary size and mathematical skills is already documented in the literature, this study further examines how children's ability to map a novel word to an unknown object as... | 10.1016/j.infbeh.2021.101573 | 34,058,633 | D002648:Child; D000084542:Eye-Tracking Technology; D006801:Humans; D019359:Knowledge; D007804:Language Development; D008137:Longitudinal Studies; D012660:Semantics; D014706:Verbal Learning; D014825:Vocabulary | Infant behavior & development | 2,021 | |
Influence of mutations of Val226 on the catalytic rate of haloalkane dehalogenase. | Haloalkane dehalogenase converts haloalkanes to their corresponding alcohols. The 3D structure, reaction mechanism and kinetic mechanism have been studied. The steady state k(cat) with 1,2-dichloroethane and 1,2-dibromoethane is limited mainly by the rate of release of the halide ion from the buried active-site cavity.... | 10.1093/protein/10.1.53 | 9,051,734 | D002384:Catalysis; D015946:Ethylene Dibromide; D005025:Ethylene Dichlorides; D006867:Hydrolases; D007700:Kinetics; D016297:Mutagenesis, Site-Directed; D015202:Protein Engineering; D013329:Structure-Activity Relationship | Protein engineering | 1,997 | D005025:Ethylene Dichlorides; D015946:Ethylene Dibromide; C024565:ethylene dichloride; D006867:Hydrolases; C046137:haloalkane dehalogenase |
Role of calcium-activated chloride current in regulating pulmonary vasomotor tone. | Many agonists induce vasoconstriction by releasing intracellularly stored Ca2+ and promoting Ca2+ influx. Activation of Ca(2+)-activated Cl- (ClCa) channels may be a critical mechanism by which a rise in intracellular free Ca2+ concentration ([Ca2+]i) causes membrane depolarization that serves to sustain the elevated [... | 10.1152/ajplung.1997.272.5.L959 | 9,176,262 | D000818:Animals; D002118:Calcium; D018118:Chloride Channels; D004553:Electric Conductivity; D004594:Electrophysiology; D007425:Intracellular Membranes; D009544:Niflumic Acid; D009994:Osmolar Concentration; D010656:Phenylephrine; D011651:Pulmonary Artery; D051381:Rats; D012701:Serotonin; D014661:Vasoconstriction; D01466... | The American journal of physiology | 1,997 | D018118:Chloride Channels; D014662:Vasoconstrictor Agents; D010656:Phenylephrine; D012701:Serotonin; D009544:Niflumic Acid; D002118:Calcium |
[Comparison and clinical application of two methods for determination of plasma chitotriosidase activity]. | OBJECTIVE
Chitotriosidase (CT) is a plasma biomarker for Gaucher disease (GD), the enzyme activity is usually markedly elevated in plasma of Gaucher patients, and it was reported that levels of plasma chitotriosidase activity was mildly-moderately increased in patients with Niemann-Pick disease (NPD). The aim of this s... | 23,302,614 | D000293:Adolescent; D000328:Adult; D001774:Blood Chemical Analysis; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005776:Gaucher Disease; D005838:Genotype; D006579:Heterozygote; D006596:Hexosaminidases; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009154:... | Zhonghua er ke za zhi = Chinese journal of pediatrics | 2,012 | D006596:Hexosaminidases; C086400:chitotriosidase | |
[Pre and post-operative autotransfusion. A comparative study of hematology, biochemistry and red cell metabolism in pre-donated blood and blood from post-operative surgical drainage]. | PURPOSE
The widespread use of aggressive surgical procedures, along with the increasing incidence of traffic accidents, has raised the necessity of homologous blood beyond the supplies of blood banks. This fact, plus the risks of homologous transfusion and the costs of blood bank maintenance, has prompted the advance o... | 10,822,758 | D019794:2,3-Diphosphoglycerate; D000063:Accidents, Traffic; D000255:Adenosine Triphosphate; D000328:Adult; D001804:Blood Transfusion, Autologous; D006348:Cardiac Surgical Procedures; D004322:Drainage; D004912:Erythrocytes; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins; D006801:Humans; D008297:Male; D008875:Mi... | Sangre | 1,999 | D006454:Hemoglobins; D019794:2,3-Diphosphoglycerate; D000255:Adenosine Triphosphate | |
Overuse of helicopter transport in the minimally injured: A health care system problem that should be corrected. | BACKGROUND
Mortality benefit has been demonstrated for trauma patients transported via helicopter but at great cost. This study identified patients who did not benefit from helicopter transport to our facility and demonstrates potential cost savings when transported instead by ground.
METHODS
We performed a 6-year (2... | 10.1097/TA.0000000000000553 | 25,710,420 | D000328:Adult; D017732:Air Ambulances; D000401:Aircraft; D000552:Ambulances; D001130:Arizona; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D057216:Propensity Score; D012042:Registries; D012189:Retrospective Studies | The journal of trauma and acute care surgery | 2,015 | |
Disruption of protein synthesis as antifungal mode of action by chitosan. | The antimicrobial activity of chitosan has been acknowledged for more than 30 years and yet its mode-of-action remains ambiguous. We analyzed chemical-genetic interactions of low-molecular weight chitosan using a collection of ≈ 4600 S. cerevisiae deletion mutants and found that 31% of the 107 mutants most sensitive to... | 23,624,539 | D000935:Antifungal Agents; D002462:Cell Membrane; D048271:Chitosan; D004789:Enzyme Activation; D008826:Microbial Sensitivity Tests; D014176:Protein Biosynthesis; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D017384:Sequence Deletion; D001616:beta-Galactosidase | International journal of food microbiology | 2,013 | D000935:Antifungal Agents; D029701:Saccharomyces cerevisiae Proteins; D048271:Chitosan; D001616:beta-Galactosidase | |
The use of a xenogeneic collagen matrix at the time of implant placement to increase the volume of buccal soft tissue. | The purpose of this study was to evaluate the efficacy of Mucograft (MG; a porcine-derived purified collagen membrane) to increase the thickness and height of the buccal soft tissue when placed at the time of implant placement in patients with thin or deficient keratinized tissue (KT). The primary endpoint of the study... | 10.11607/prd.2226 | 25,738,338 | D002610:Cheek; D003094:Collagen; D015921:Dental Implants; D006801:Humans; D010514:Periodontal Pocket | The International journal of periodontics & restorative dentistry | 2,015 | D015921:Dental Implants; D003094:Collagen |
Topology description for data distributions using a topology graph with divide-and-combine learning strategy. | The topologies of data distributions are very important for data description. Usually, it is not easy to find a description that can give us an intuitional understanding of the topologies for general distributions. In this paper, a novel concept, a topology graph, is proposed as a description for the principal topology... | 10.1109/tsmcb.2006.875863 | 17,186,806 | IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics : a publication of the IEEE Systems, Man, and Cybernetics Society | 2,006 | ||
Self-assembled HCV core virus-like particles targeted and inhibited tumor cell migration and invasion. | We used a baculovirus expression system to express fusion proteins of HCV core, RGD (Arg-Gly-Asp) peptide, and IFN-α2a fragments in Sf9 cells. Western blotting and electron microscopy demonstrate that HCV core, peptides RGD, and IFN-α2a fusion proteins assemble into 30 to 40 nm nano-particles (virus-like particles, VLP... | 10.1186/1556-276X-8-401 | 24,074,276 | Nanoscale research letters | 2,013 | ||
Deciphering the role of UBA-like domains in intraflagellar distribution and functions of myosin XXI in Leishmania. | Myosin XXI (Myo21) is a novel class of myosin present in all kinetoplastid parasites, such as Trypanosoma and Leishmania. This protein in Leishmania promastigotes is predominantly localized to the proximal region of the flagellum, and is involved in the flagellum assembly, cell motility and intracellular vesicle transp... | 10.1371/journal.pone.0232116 | 32,343,719 | D000199:Actins; D002453:Cell Cycle; D005407:Flagella; D049452:Green Fluorescent Proteins; D007893:Leishmania donovani; D009218:Myosins; D000072417:Protein Domains; D015800:Protozoan Proteins; D011994:Recombinant Proteins; D017384:Sequence Deletion; D022161:Transport Vesicles; D025801:Ubiquitin | PloS one | 2,020 | D000199:Actins; D015800:Protozoan Proteins; D011994:Recombinant Proteins; D025801:Ubiquitin; D049452:Green Fluorescent Proteins; D009218:Myosins |
Polyphenols and avenanthramides extracted from oat (Avena sativa L.) grains and sprouts modulate genes involved in glucose and lipid metabolisms in 3T3 L1 adipocytes. | This study aimed to evaluate the effect of polyphenol (PE) and avenanthramide (AE) extracts from oat grains (OG) and sprouts (OS) on genes related to glucose and lipid metabolisms in 3T3 L1 adipocytes. The AE-OS exerted the greatest effect on genes involved in glucose metabolism, increasing Glut4, Irs1, and Pi3k expres... | 10.1111/jfbc.13738 | 33,899,247 | D041721:3T3-L1 Cells; D017667:Adipocytes; D000818:Animals; D018554:Avena; D002851:Chromatography, High Pressure Liquid; D005947:Glucose; D050356:Lipid Metabolism; D051379:Mice; D059808:Polyphenols; D062367:ortho-Aminobenzoates | Journal of food biochemistry | 2,021 | D059808:Polyphenols; D062367:ortho-Aminobenzoates; C514463:avenanthramide-2C; D005947:Glucose |
Is Survival for Patients with Resectable Lung Metastatic Colorectal Cancer Comparable to Those with Resectable Liver Disease? Results from the South Australian Metastatic Colorectal Registry. | BACKGROUND
Hepatic resection for colorectal (CRC) metastasis is considered a standard of care. Resection of metastasis isolated to lung also is considered potentially curable, although there is still some variation in recommendations. We explore outcomes for patients undergoing lung resection for mCRC, with the liver r... | 10.1245/s10434-016-5290-4 | 27,251,133 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008113:Liver Neoplasms; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Ther... | Annals of surgical oncology | 2,016 | D000970:Antineoplastic Agents |
Minimal Cardiac Perforation by Lead Pacemaker Complicated with Pericardial Effusion and Impending Tamponade: Optimal Management with No Pericardiocentesis Driven by Echocardiography. | We report the case of a 51-year-old patient who underwent the implantation of a bi-ventricular implantable cardioverter defibrillator (ICD) complicated by a sub-acute right ventricular minimal perforation with pericardial effusion and echocardiographic signs of tamponade. A new echocardiographic plane orientation allow... | 10.3390/diagnostics10040191 | 32,235,447 | Diagnostics (Basel, Switzerland) | 2,020 | ||
Distinct facial processing related negative cognitive bias in first-episode and recurrent major depression: evidence from the N170 ERP component. | BACKGROUND
States of depression are associated with increased sensitivity to negative events. For this novel study, we have assessed the relationship between the number of depressive episodes and the dysfunctional processing of emotional facial expressions.
METHODOLOGY/PRINCIPAL FINDINGS
We used a visual emotional od... | 10.1371/journal.pone.0109176 | 25,314,024 | D000293:Adolescent; D000328:Adult; D000368:Aged; D003710:Demography; D003865:Depressive Disorder, Major; D004569:Electroencephalography; D004644:Emotions; D005071:Evoked Potentials; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012044:Regression Analy... | PloS one | 2,014 | |
miR-15/16 clusters restrict effector Treg cell differentiation and function. | Effector regulatory T cells (eTregs) exhibit distinct homeostatic properties and superior suppressor capacities pivotal for controlling immune responses mediated by their conventional T cell counterpart. While the role of microRNAs (miRNAs) in Tregs has been well-established, how miRNAs regulate eTregs remains poorly u... | 10.1084/jem.20230321 | 37,516,921 | D000818:Animals; D051379:Mice; D050378:T-Lymphocytes, Regulatory; D008213:Lymphocyte Activation; D002454:Cell Differentiation; D006706:Homeostasis; D035683:MicroRNAs | The Journal of experimental medicine | 2,023 | D035683:MicroRNAs |
Detector arrangement and sampling characteristics in rotary positron-emission computed tomography. | A rotary positron-emission computed tomography system has been proposed in which detectors are mounted unequally spaced on a ring, so as to provide fine and uniform linear sampling during a 360 degree rotation of the ring around its centre. The usefulness of a simple iterative method for searching for a suitable arrang... | 10.1088/0031-9155/26/3/011 | 6,972,540 | D013679:Technology, Radiologic; D014055:Tomography, Emission-Computed | Physics in medicine and biology | 1,981 | |
Pathogenesis of alcoholic liver disease with particular emphasis on oxidative stress. | Oxidative stress is well recognized to be a key step in the pathogenesis of ethanol-associated liver injury. Ethanol administration induces an increase in lipid peroxidation either by enhancing the production of oxygen reactive species and/or by decreasing the level of endogenous antioxidants. Numerous experimental stu... | 10.1111/j.1440-1746.1997.tb00510.x | 9,407,347 | D000079:Acetaldehyde; D000818:Animals; D000431:Ethanol; D006801:Humans; D008099:Liver; D008108:Liver Diseases, Alcoholic; D018384:Oxidative Stress; D010088:Oxidoreductases; D017382:Reactive Oxygen Species | Journal of gastroenterology and hepatology | 1,997 | D017382:Reactive Oxygen Species; D000431:Ethanol; D010088:Oxidoreductases; D000079:Acetaldehyde |
Histamine H1 receptor binding capacities in the amygdalas of the amygdaloid kindled rat. | The histamine H1 receptor binding capacity of the amygdalas of amygdaloid kindled rats was studied. In the kindled nonstimulated amygdala, significant decreases in K(D) and B(max) values compared with those of control amygdala were found 1 week after the last kindled seizure. One month after the last kindled seizure, t... | 10.1046/j.1471-4159.1999.0722177.x | 10,217,300 | D000679:Amygdala; D000818:Animals; D004198:Disease Susceptibility; D004292:Dominance, Cerebral; D006634:Histamine H1 Antagonists; D007696:Kindling, Neurologic; D008297:Male; D011738:Pyrilamine; D051381:Rats; D017207:Rats, Sprague-Dawley; D011969:Receptors, Histamine H1; D012640:Seizures | Journal of neurochemistry | 1,999 | D006634:Histamine H1 Antagonists; D011969:Receptors, Histamine H1; D011738:Pyrilamine |
Abdominal ultrasound with scintigraphic and clinical correlates in infants with sickle cell anemia: baseline data from the BABY HUG trial. | OBJECTIVE
The purpose of this study is to perform and evaluate baseline abdominal ultrasound in infants with sickle cell anemia who participated in the BABY HUG multiinstitutional randomized placebo-controlled trial of hydroxyurea therapy and to examine the potential relationships among ultrasound results and clinical,... | 10.2214/AJR.10.4664 | 21,606,305 | D000005:Abdomen; D000410:Alanine Transaminase; D000704:Analysis of Variance; D000755:Anemia, Sickle Cell; D000986:Antisickling Agents; D001663:Bilirubin; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006918:Hydroxyurea; D007223:Infant; D007668:Kidney; D008297:Male; D010919:Placebos; D011877:Radio... | AJR. American journal of roentgenology | 2,011 | D000986:Antisickling Agents; D010919:Placebos; D013671:Technetium Tc 99m Sulfur Colloid; D000410:Alanine Transaminase; D001663:Bilirubin; D006918:Hydroxyurea |
Dramatic Drop in U.S. Childhood Poverty. | Safety net programs are credited, along with employment opportunities for parents. | 10.1097/01.NAJ.0000904040.19174.9d | 36,384,781 | D002648:Child; D006801:Humans; D000091486:Child Poverty; D011203:Poverty; D010290:Parents | The American journal of nursing | 2,022 | |
Graph-based rotational nonuniformity correction for localized compliance measurement in the human nasopharynx. | Recent advancements in the high-speed long-range optical coherence tomography (OCT) endoscopy allow characterization of tissue compliance in the upper airway, an indicator of collapsibility. However, the resolution and accuracy of localized tissue compliance measurement are currently limited by the lack of a reliable n... | 10.1364/BOE.419997 | 33,996,244 | Biomedical optics express | 2,021 | ||
A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection. | Antigen-specific CD4 and CD8 T cells are important components of the immune response to Mycobacterium tuberculosis, yet little information is currently known regarding how the breadth, specificity, phenotype, and function of M. tuberculosis-specific T cells correlate with M. tuberculosis infection outcome in humans. To... | 10.4049/jimmunol.1701737 | 29,540,577 | D003430:Cross-Sectional Studies; D006403:Hematologic Tests; D057166:High-Throughput Screening Assays; D006801:Humans; D007158:Immunologic Techniques; D008137:Longitudinal Studies; D015203:Reproducibility of Results; D013601:T-Lymphocytes; D014376:Tuberculosis | Journal of immunology (Baltimore, Md. : 1950) | 2,018 | |
Vitamin E-coated polysulfone membrane improved red blood cell antioxidant status in hemodialysis patients. | BACKGROUND
Oxidative stress has emerged as a strong pathogenic cofactor implicated in the development of long-term complications in hemodialysis (HD) patients, such as anemia, and as a major component of the malnutrition inflammation complex syndrome. This prospective multicenter study aimed at evaluating the short-ter... | 10.5301/jn.5000195 | 22,956,433 | D000740:Anemia; D000975:Antioxidants; D020099:Coated Materials, Biocompatible; D004912:Erythrocytes; D004921:Erythropoietin; D005260:Female; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D018384:Oxidative Stress; D011108:Polymers; D011446:Prospective Studies; D006435:Renal Dialysis; ... | Journal of nephrology | 2,013 | D000975:Antioxidants; D020099:Coated Materials, Biocompatible; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; D004921:Erythropoietin; D014810:Vitamin E; C017662:polysulfone P 1700 |
A Cys-less variant of the bacterial ATP binding cassette protein MalK is functional in maltose transport and regulation. | The cysteine residues of the ABC protein MalK from Salmonella typhimurium maltose transport system (C40, C350, C360) were consecutively replaced by serines. Cys-less MalK was fully functional in maltose transport in vivo. Moreover, the activity of MalK as a repressor of other maltose-regulated genes was also retained. ... | 10.1016/s0014-5793(99)00356-7 | 10,217,425 | D018528:ATP-Binding Cassette Transporters; D000251:Adenosine Triphosphatases; D000255:Adenosine Triphosphate; D001426:Bacterial Proteins; D001692:Biological Transport; D003545:Cysteine; D004791:Enzyme Inhibitors; D005033:Ethylmaleimide; D008320:Maltose; D016297:Mutagenesis, Site-Directed; D012486:Salmonella typhimurium... | FEBS letters | 1,999 | D018528:ATP-Binding Cassette Transporters; D001426:Bacterial Proteins; D004791:Enzyme Inhibitors; C068021:MalK protein, Bacteria; C489399:MalK protein, Salmonella typhimurium; D012694:Serine; D008320:Maltose; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D003545:Cysteine; D005033:Ethylmaleimide |
Improved WO3 photocatalytic efficiency using ZrO2 and Ru for the degradation of carbofuran and ampicillin. | The photocatalytic degradation of carbofuran (pesticide) and ampicillin (pharmaceutical) using synthesized WO3/ZrO2 nanoparticles under simulated solar light was investigated. Transmission electron microscopy (TEM), X-ray diffraction (XRD), and Raman spectra analyses were used to characterize the prepared catalysts. Th... | 10.1016/j.jhazmat.2015.10.002 | 26,476,309 | D000667:Ampicillin; D002235:Carbofuran; D053758:Nanoparticles; D010087:Oxides; D010782:Photolysis; D012428:Ruthenium; D014414:Tungsten; D014874:Water Pollutants, Chemical; D015040:Zirconium | Journal of hazardous materials | 2,016 | D010087:Oxides; D014874:Water Pollutants, Chemical; D000667:Ampicillin; D012428:Ruthenium; C511604:tungsten oxide; D015040:Zirconium; C028541:zirconium oxide; D002235:Carbofuran; D014414:Tungsten |
Tarsal bone disintegration in leprosy. | Tarsal bone disintegration is characterised by fragmentation and progressive collapse of one or more tarsal bones. It occurs in 10% of leprosy patients, and is responsible for many severe foot deformities associated with this disease. The main cause is micro-traumata, but sensory impairment, sepsis and osteoporosis are... | 10.1016/s0009-9260(79)80092-6 | 455,906 | D000293:Adolescent; D000328:Adult; D001847:Bone Diseases; D005260:Female; D006801:Humans; D007918:Leprosy; D008297:Male; D011859:Radiography; D012598:Sclerosis; D013639:Tarsal Bones; D013997:Time Factors | Clinical radiology | 1,979 | |
Risk factors for high myopia: a 22-year follow-up study from childhood to adulthood. | PURPOSE
To determine the effect of the definition of high myopia on its prevalence and risk factors for high myopia.
METHODS
A total of 240 myopic schoolchildren (119 boys and 121 girls) at the mean age of 10.9 years (range 8.8-12.8 years) were recruited to a randomized clinical trial of myopia treatment among childr... | 10.1111/aos.13964 | 30,460,746 | D000293:Adolescent; D000328:Adult; D002648:Child; D018450:Disease Progression; D005139:Eyeglasses; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D008297:Male; D009216:Myopia; D015995:Prevalence; D012029:Refraction, Ocular; D012189:Retrospective Studies; D012307:Risk Fa... | Acta ophthalmologica | 2,019 | |
[Carpal tunnel syndrome- etiology and treatment]. | The paper presents the etiology, diagnostics,
management, treatment and
prognosis of carpal tunnel syndrome.
The mechanism of the median nerve
compression as well as the predisposing
factors that cause the syndrome
are discussed, as well as the sequence
of specific symptoms and the classification
of the level of severi... | 29,677,425 | D002349:Carpal Tunnel Syndrome; D006801:Humans | Przeglad lekarski | 2,016 | ||
Development of primary visual projections occurs entirely postnatally in the fat-tailed dunnart, a marsupial mouse, Sminthopsis crassicaudata. | We have examined the development of retinal projections in a diminutive polyprotodont marsupial, the fat-tailed dunnart, Sminthopsis crassicaudata. Here, we document the most immature mammalian visual system at birth described to date. At postnatal day (P) 0, the retinal ganglion cell layer has yet to form, and axons h... | 9,214,538 | D000367:Age Factors; D000818:Animals; D002232:Carbocyanines; D004622:Embryo, Mammalian; D005123:Eye; D005260:Female; D005456:Fluorescent Dyes; D005829:Geniculate Bodies; D008297:Male; D008394:Marsupialia; D008854:Microscopy, Electron; D009475:Neurons, Afferent; D009900:Optic Nerve; D012160:Retina; D013477:Superior Coll... | The Journal of comparative neurology | 1,997 | C101089:CM-DiI; D002232:Carbocyanines; D005456:Fluorescent Dyes | |
Bite force and handgrip force in patients with molecular diagnosis of myotonic dystrophy. | Myotonic dystrophy is a multisystemic disease with varying symptomatology. The aim of this study was to compare the maximal bite force and handgrip force in patients with molecular diagnosis of myotonic dystrophy with those in a group of healthy individuals. It was hypothesized that these forces were reduced in the pat... | 10.1111/j.1365-2842.2006.01665.x | 17,302,947 | D000293:Adolescent; D000328:Adult; D001732:Bite Force; D002648:Child; D005192:Family Health; D005260:Female; D007839:Functional Laterality; D018737:Hand Strength; D006801:Humans; D008297:Male; D008410:Masticatory Muscles; D008875:Middle Aged; D053581:Muscle Strength Dynamometer; D009223:Myotonic Dystrophy; D012737:Sex ... | Journal of oral rehabilitation | 2,007 | |
Active transport and exchange diffusion of Cl across the isolated skin of Rana pipiens. | Transepithelial Cl influx and efflux were measured in pairs of frog skin (Rana pipiens) matched according to short-circuit current, tissue conductance, and transepithelial potential (TEP). The skins were bathed symmetrically in NaCl Ringer and voltage clamped at TEP values ranging from -60 to +60 mV. At 0 TEP, Cl influ... | 10.1152/ajprenal.1985.249.3.F424 | 3,876,034 | D000818:Animals; D001692:Biological Transport; D001693:Biological Transport, Active; D002712:Chlorides; D004058:Diffusion; D004848:Epithelium; D005260:Female; D007700:Kinetics; D008297:Male; D008564:Membrane Potentials; D011894:Rana pipiens; D012867:Skin; D012879:Skin Physiological Phenomena; D012964:Sodium | The American journal of physiology | 1,985 | D002712:Chlorides; D012964:Sodium |
New ambuic acid derivatives from the solid culture of Pestalotiopsis neglecta and their nitric oxide inhibitory activity. | Four new ambuic acid derivatives (1-4), and four known derivatives (5-8), were isolated from the solid culture of a plant pathogenic fungus Pestalotiopsis neglecta. Their structures were elucidated by extensive NMR experiments. The absolute configuration of the C-16 secondary alcohol in 1 was deduced via the CD data of... | 10.1038/srep09958 | 25,989,228 | D001203:Ascomycota; D003512:Cyclohexanones; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D009569:Nitric Oxide | Scientific reports | 2,015 | D003512:Cyclohexanones; C429363:ambuic acid; D009569:Nitric Oxide |
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