title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
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Erythrocyte lipids in triose-phosphate isomerase deficiency. | Marked hypoalphalipoproteinemia was found together with relatively low serum cholesterol, triacylglycerol, and LDL levels in a triose-phosphate isomerase (TPI; D-glyceraldehyde-3-phosphate ketol-isomerase, EC 5.3.1.1)-deficient Hungarian family, especially in the two compound-heterozygote brothers. Apart from a slight ... | 10.1073/pnas.92.1.268 | 7,816,830 | D000328:Adult; D001053:Apolipoproteins; D002239:Carbohydrate Metabolism, Inborn Errors; D002648:Child; D002784:Cholesterol; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004795:Enzyme Stability; D004910:Erythrocyte Membrane; D004912:Erythrocytes; D005260:Female; D005454:Fluorescence Polarization; D006579:Heteroz... | Proceedings of the National Academy of Sciences of the United States of America | 1,995 | D001053:Apolipoproteins; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008051:Lipid Bilayers; D008055:Lipids; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol; D014305:Triose-Phosphate Isomerase |
Predictive value of 1H MRSI for outcome in temporal lobectomy. | OBJECTIVE
To investigate the predictive value of 1H MRSI for outcome in patients with mesial temporal lobe epilepsy (MTLE).
BACKGROUND
1H MRSI has been shown to be highly sensitive in the lateralization of temporal lob epilepsy.
METHODS
The authors analyzed the relationship between the 1H MRSI findings and surgical... | 10.1212/wnl.53.4.694 | 10,489,028 | D000293:Adolescent; D000328:Adult; D004833:Epilepsy, Temporal Lobe; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011237:Predictive Value of Tests; D011522:Protons; D013702:Temporal Lobe | Neurology | 1,999 | D011522:Protons |
Identifying Predictors of Recommendations for and Participation in Multimodal Nonpharmacological Treatments for Chronic Pain Using Patient-Reported Outcomes and Electronic Medical Records. | OBJECTIVE
High-quality chronic pain care emphasizes multimodal treatments that include medication and nonpharmacological treatments. But it is not clear which patients will participate in nonpharmacological treatments, such as physical therapy or mental health care, and previous research has shown conflicting evidence.... | 10.1093/pm/pnaa203 | 32,869,082 | D000701:Analgesics, Opioid; D059350:Chronic Pain; D003131:Combined Modality Therapy; D057286:Electronic Health Records; D005260:Female; D006801:Humans; D008297:Male; D000071066:Patient Reported Outcome Measures | Pain medicine (Malden, Mass.) | 2,020 | D000701:Analgesics, Opioid |
Investigation of obesity, eating behaviors and physical activity levels living in rural and urban areas during the covid-19 pandemic era: a study of Turkish adolescent. | BACKGROUND
The purpose of this study was to determine the eating behaviors, obesity and physical activity status of children of similar ages living in rural and urban areas and to examine these relationships during the coronavirus disease (COVID-19) pandemic process.
METHOD
The research was conducted using the scanni... | 10.1186/s12887-022-03473-1 | 35,820,871 | D000293:Adolescent; D000086382:COVID-19; D002648:Child; D003430:Cross-Sectional Studies; D015444:Exercise; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D058873:Pandemics; D063766:Pediatric Obesity; D015995:Prevalence; D014421:Turkey | BMC pediatrics | 2,022 | |
Eighteen microsatellite loci in Salix arbutifolia (Salicaceae) and cross-species amplification in Salix and Populus species. | Salix arbutifolia is a riparian dioecious tree species that is of conservation concern in Japan because of its highly restricted distribution. Eighteen polymorphic loci of dinucleotide microsatellites were isolated and characterized. Among these, estimates of the expected heterozygosity ranged from 0.350 to 0.879. Cros... | 10.1111/j.1755-0998.2009.02607.x | 21,564,876 | Molecular ecology resources | 2,009 | ||
Quantitative trait loci and candidate genes underlying genotype by environment interaction in the response of Arabidopsis thaliana to drought. | Drought stress was imposed on two sets of Arabidopsis thaliana genotypes grown in sand under short-day conditions and analysed for several shoot and root growth traits. The response to drought was assessed for quantitative trait locus (QTL) mapping in a genetically diverse set of Arabidopsis accessions using genome-wid... | 10.1111/pce.12418 | 25,074,022 | D017360:Arabidopsis; D002874:Chromosome Mapping; D055864:Droughts; D004777:Environment; D059647:Gene-Environment Interaction; D008040:Genetic Linkage; D014644:Genetic Variation; D055106:Genome-Wide Association Study; D005838:Genotype; D010641:Phenotype; D018517:Plant Roots; D018520:Plant Shoots; D020641:Polymorphism, S... | Plant, cell & environment | 2,015 | |
Effects of Arachidonic and Docosohexahenoic Acid Supplementation during Gestation in Rats. Implication of Placental Oxidative Stress. | Arachidonic and docosahexaenoic acids (ARA and DHA) are important during pregnancy. However, the effects of dietary supplementation on fetal growth and oxidative stress are inconclusive. We aimed to assess the effect of high ARA and DHA diet during rat gestation on: (1) ARA and DHA availability in plasma and placenta, ... | 10.3390/ijms19123863 | 30,518,038 | D000818:Animals; D016718:Arachidonic Acid; D004032:Diet; D019587:Dietary Supplements; D004281:Docosahexaenoic Acids; D005260:Female; D047109:Fetal Development; D020567:Fetal Weight; D005333:Fetus; D015227:Lipid Peroxidation; D008297:Male; D009929:Organ Size; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D01092... | International journal of molecular sciences | 2,018 | D004281:Docosahexaenoic Acids; D016718:Arachidonic Acid |
Information items to improve Integration Readiness Levels evaluation. | Systems integration is critical to the engineering of successful complex products and systems. The Technology Readiness Levels (TRL) scale assists in making decisions about the infusion of new technologies into complex systems. This scale presents challenges to represent the integration between technologies in a system... | 10.1590/0001-3765202020190685 | 33,295,483 | D001938:Brazil; D002681:China; D013672:Technology | Anais da Academia Brasileira de Ciencias | 2,020 | |
Destruction of intracerebrally applied red blood cells in cervical lymph nodes. Experimental investigations. | In rabbits, intracerebrally applied erythrocytes can move with the cerebrospinal fluid along connecting pathways between the subarachnoid space and the cervical lymph nodes. This study compares the time dependency for the degradation of intracerebrally injected erythrocytes in the brain as well as in the cervical lymph... | 10.1016/0379-0738(83)90089-0 | 6,826,120 | D000818:Animals; D001921:Brain; D004912:Erythrocytes; D006644:Histiocytes; D007267:Injections; D008198:Lymph Nodes; D008264:Macrophages; D009333:Neck; D010586:Phagocytes; D010587:Phagocytosis; D011817:Rabbits; D013355:Subdural Space | Forensic science international | 1,983 | |
Utilization of intravenously administered glycogen by young pigs. | Previous studies evaluated solutions of small oligosaccharides as potential sources of carbohydrate-derived energy for patients fed intravenously. Although results with these solutions were disappointing, the data suggested that very large oligosaccharides were potential sources of intravenous carbohydrate. To test thi... | 10.1093/jn/117.2.274 | 3,559,742 | D000818:Animals; D001786:Blood Glucose; D002241:Carbohydrates; D006003:Glycogen; D007262:Infusions, Intravenous; D008320:Maltose; D009844:Oligosaccharides; D013552:Swine | The Journal of nutrition | 1,987 | D001786:Blood Glucose; D002241:Carbohydrates; D009844:Oligosaccharides; D008320:Maltose; D006003:Glycogen; C009819:maltotetraose |
Dysmegakaryocytopoiesis in acute leukaemias: its predominance in myelomonocytic (M4) leukaemia and implication for poor response to chemotherapy. | Megakaryocytopoiesis was morphologically investigated in 129 adults with de novo acute leukaemia. Three types were identified: type I (84 cases), no detectable megakaryocytes; type II (32 cases), quantitatively preserved megakaryocytes with normal morphology; type III (13 cases); quantitatively preserved megakaryocytes... | 10.1111/j.1365-2141.1987.tb01328.x | 3,478,075 | D000208:Acute Disease; D000328:Adult; D001853:Bone Marrow; D005260:Female; D006410:Hematopoiesis; D006801:Humans; D007938:Leukemia; D015470:Leukemia, Myeloid, Acute; D008297:Male; D008533:Megakaryocytes; D008875:Middle Aged | British journal of haematology | 1,987 | |
Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1, and ATF2 control the formation of a broad range of volatile esters. | Volatile aroma-active esters are responsible for the fruity character of fermented alcoholic beverages such as beer and wine. Esters are produced by fermenting yeast cells in an enzyme-catalyzed intracellular reaction. In order to investigate and compare the roles of the known Saccharomyces cerevisiae alcohol acetyltra... | 10.1128/AEM.69.9.5228-5237.2003 | 12,957,907 | D000123:Acetyltransferases; D004952:Esters; D005285:Fermentation; D017353:Gene Deletion; D005800:Genes, Fungal; D007700:Kinetics; D010957:Plasmids; D011506:Proteins; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D013379:Substrate Specificity | Applied and environmental microbiology | 2,003 | D004952:Esters; D011506:Proteins; D029701:Saccharomyces cerevisiae Proteins; D000123:Acetyltransferases; C116217:ATF2 protein, S cerevisiae; C079238:alcohol O-acetyltransferase |
The medical and surgical treatment of drug-resistant tuberculosis. | Multi drug-resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB) are burgeoning global problems with high mortality which threaten to destabilise TB control programs in several parts of the world. Of alarming concern is the emergence, in large numbers, of patients with resistance beyond XDR-TB (tot... | 10.3978/j.issn.2072-1439.2013.11.11 | 24,624,282 | Journal of thoracic disease | 2,014 | ||
Are islands the end of the colonization road? | Ecologists have, up to now, widely regarded colonization of islands from continents as a one-way journey, mainly because of widely accepted assertions that less diverse island communities are easier to invade. However, continents present large targets and island species should be capable of making the reverse journey, ... | 10.1016/j.tree.2008.05.001 | 18,584,910 | D000818:Animals; D005843:Geography; D010802:Phylogeny; D011157:Population Dynamics; D014714:Vertebrates | Trends in ecology & evolution | 2,008 | |
A rare initial presentation of gastric cancer with multiple osteolytic lesions. | Gastric cancer is the 12th leading cause of cancer-related deaths in the United States and commonly metastasizes to the bones. However, the presentation of gastric cancer as bony metastases without preceding gastrointestinal symptoms is rare which has been infrequently reported in the literature. Moreover, leptomeninge... | 10.1155/2015/689431 | 25,984,375 | Case reports in oncological medicine | 2,015 | ||
Control of viscous fingering by nanoparticles. | A substantial viscosity increase by the addition of a low dose of nanoparticles to the base fluids can well influence the dynamics of viscous fingering. There is a lack of detailed theoretical studies that address the effect of the presence of nanoparticles on unstable miscible displacements. In this study, the impact ... | 10.1103/PhysRevE.96.063114 | 29,347,363 | Physical review. E | 2,017 | ||
Altered circadian patterns of salivary cortisol in individuals with schizophrenia: A critical literature review. | This article focuses on stress vulnerability in schizophrenia through an integrated clinical and biological approach. The objective of this article is to better understand the relationships between vulnerability, stress and schizophrenia. First, the concept of vulnerability is defined and several models of vulnerabilit... | 10.1016/j.jphysparis.2017.05.002 | 28,506,881 | D000818:Animals; D015415:Biomarkers; D002940:Circadian Rhythm; D006801:Humans; D006854:Hydrocortisone; D012463:Saliva; D012559:Schizophrenia; D013315:Stress, Psychological | Journal of physiology, Paris | 2,016 | D015415:Biomarkers; D006854:Hydrocortisone |
Association of mitochondrial variants A4336G of the tRNAGln gene and 8701G/A of the MT-ATP6 gene in Mexicans Mestizos with Parkinson disease. | INTRODUCTION
Sporadic Parkinson's disease (PD) is a neurodegenerative disorder of unknown etiology. In recent years, it has been established that a genetic component underlies different forms of the disease. For instance, mitochondrial genome variants have been implicated in the pathogenesis of the PD.
AIM OF THE STU... | 10.5114/fn.2019.89859 | 32,337,946 | D004272:DNA, Mitochondrial; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D008800:Mexico; D008928:Mitochondria; D025261:Mitochondrial Proton-Translocating ATPases; D010300:Parkinson Disease; D011110:Polymorphism, Genetic; D012351:RNA, Transfer, Gln | Folia neuropathologica | 2,019 | D004272:DNA, Mitochondrial; C501005:MT-ATP6 protein, human; D012351:RNA, Transfer, Gln; D025261:Mitochondrial Proton-Translocating ATPases |
Stingless bee (Apidae, Meliponini) guilds occurring in the immediate edges of forest fragments of the Baturité Massif, State of Ceará, Brazil. | This study investigated the occurrence of individuals of stingless bees attracted by the trophic resources existing in four edge areas of forest fragments located in the Baturité Massif, State of Ceará. In this sense, the study evaluated the species richness in the areas; the absolute abundance of species; the similari... | 10.1590/0001-3765202020181303 | 32,813,767 | D000818:Animals; D001516:Bees; D001938:Brazil; D065928:Forests | Anais da Academia Brasileira de Ciencias | 2,020 | |
Methodology development for simultaneous diffuse optical tomography and magnetic resonance imaging in functional human brain mapping. | We present an integrated methodology for human brain mapping by simultaneous BOLD fMRI and NIR imaging. This methodology consists of three innovative components: the construction of MRI-compatible optical probes that can be affixed to any part of the human head inside a standard MRI head-coil with minimal MR image dist... | 10.1117/12.593432 | 21,796,235 | Proceedings of SPIE--the International Society for Optical Engineering | 2,005 | ||
Renal phosphate handling in nephrotic syndrome during water immersion. | In 11 patients suffering from nephrotic syndrome, renal phosphate handling was studied in water immersion up to the neck. There was a rapid onset of phosphate diuresis which continued to increase throughout water immersion; and an increase in fractional excretion of phosphate (FEPO4) continuing throughout immersion and... | 10.1159/000182828 | 7,177,288 | D002712:Chlorides; D003404:Creatinine; D006801:Humans; D007101:Immersion; D007444:Inulin; D007668:Kidney; D009404:Nephrotic Syndrome; D010281:Parathyroid Hormone; D010710:Phosphates; D011188:Potassium; D012964:Sodium | Nephron | 1,982 | D002712:Chlorides; D010281:Parathyroid Hormone; D010710:Phosphates; D007444:Inulin; D012964:Sodium; D003404:Creatinine; D011188:Potassium |
Intraocular pressure rise after argon laser trabeculoplasty. | Eighty-four eyes received 107 argon laser trabeculoplasty treatments at Beth Israel Medical Center between 1982 and 1984 for advanced primary and secondary glaucoma. The prelaser mean pressure was 20.25 mmHg. Pressures taken 1 1/2 hours postoperatively varied widely: the pressure rose after 47 treatments and fell or re... | 10.1136/bjo.71.10.772 | 3,676,148 | D000368:Aged; D005260:Female; D005901:Glaucoma; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension; D014130:Trabeculectomy | The British journal of ophthalmology | 1,987 | |
Comparison of risk factors for colon and rectal cancer. | Predictors of colorectal cancer have been extensively studied with some evidence suggesting that risk factors vary by subsite. Using data from 2 prospective cohort studies, we examined established risk factors to determine whether they were differentially associated with colon and rectal cancer. Our study population in... | 10.1002/ijc.11540 | 14,648,711 | D000328:Adult; D015331:Cohort Studies; D003110:Colonic Neoplasms; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012004:Rectal Neoplasms; D012307:Risk Factors; D011795:Surveys and Questionnaires | International journal of cancer | 2,004 | |
Energy content of stools in normal healthy controls and patients with cystic fibrosis. | Stool energy losses and the sources of energy within the stool were determined in 20 healthy controls and 20 patients with cystic fibrosis while on their habitual pancreatic enzyme replacement treatment. Stool energy losses were equivalent to 3.5% of gross energy intake in healthy children (range 1.3-5.8%). Despite a c... | 10.1136/adc.66.4.495 | 2,031,608 | D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis; D004734:Energy Metabolism; D005243:Feces; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D009584:Nitrogen; D010194:Pancreatin | Archives of disease in childhood | 1,991 | D010194:Pancreatin; D009584:Nitrogen |
Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints. | Male F344/NCr rats were exposed to low dietary concentrations of Aroclor 1254 (0-33 ppm) for 7 days, following which the induction of selected hepatic drug metabolizing enzymes was monitored. CYP1A1, measured indirectly by assaying the O-dealkylation of ethoxyresorufin in 9000 g supernatants, was increased 1.5-, 3-, 8-... | 10.1016/s0013-9351(05)80048-9 | 1,281,448 | D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D001140:Aroclors; D001483:Base Sequence; D002273:Carcinogens; D020111:Chlorodiphenyl (54% Chlorine); D003577:Cytochrome P-450 Enzyme System; D004305:Dose-Response Relationship, Drug; D004790:Enzyme Induction; D015151:Immunoblotting; D008099:Liver; D008... | Environmental research | 1,992 | D001140:Aroclors; D002273:Carcinogens; D009838:Oligodeoxyribonucleotides; D020111:Chlorodiphenyl (54% Chlorine); D012313:RNA; D003577:Cytochrome P-450 Enzyme System; D015049:Zoxazolamine; D011078:Polychlorinated Biphenyls |
Attentional states and the degree of visual adaptation to gratings. | We studied top-down attentional effects on adaptation to two aspects of sinusoidal gratings: contrast (CTE: contrast threshold elevation for detection) and orientation (TAE: tilt aftereffect, bias in perceived orientation). Adaptation was examined under five different behavioral conditions designed to assess the effect... | 10.1016/j.neunet.2004.02.006 | 15,288,902 | D000064:Acclimatization; D000221:Adaptation, Ocular; D001288:Attention; D015350:Contrast Sensitivity; D006801:Humans; D008960:Models, Psychological; D009949:Orientation; D010364:Pattern Recognition, Visual; D010775:Photic Stimulation; D013997:Time Factors | Neural networks : the official journal of the International Neural Network Society | 2,004 | |
[Epidemiological aspects of bilateral retinoblastoma]. | Retinoblastoma (RB) is the most frequent solid tumor in the Instituto Nacional de Pediatría, México (INP). The bilateral presentation occurs in 25% of all patients. We present some epidemiological data of this form of the disease, in learn these epidemiological variables in our series. We reviewed the clinical charts f... | 8,768,597 | D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D009918:Orbital Neoplasms; D015995:Prevalence; D012175:Retinoblastoma; D012737:Sex Factors | Gaceta medica de Mexico | 1,995 | ||
Human nasal mucosa contains antigen-presenting cells of strikingly different functional phenotypes. | Professional antigen-presenting cells (APCs) constitute a heterogeneous leukocyte population that controls T cell induction. Experimental animal studies have delineated the principal APCs of the airway mucosa as a network of intraepithelial dendritic cells (DCs). Whether the situation is comparable in the human airways... | 10.1165/rcmb.2002-0230OC | 12,829,449 | D000938:Antigen-Presenting Cells; D005455:Fluorescent Antibody Technique; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D009297:Nasal Mucosa | American journal of respiratory cell and molecular biology | 2,004 | |
Early reprogramming regulators identified by prospective isolation and mass cytometry. | In the context of most induced pluripotent stem (iPS) cell reprogramming methods, heterogeneous populations of non-productive and staggered productive intermediates arise at different reprogramming time points. Despite recent reports claiming substantially increased reprogramming efficiencies using genetically modified... | 10.1038/nature14274 | 25,830,878 | D015720:5'-Nucleotidase; D000818:Animals; D015703:Antigens, CD; D000951:Antigens, Neoplasm; D015415:Biomarkers; D015815:Cell Adhesion Molecules; D002469:Cell Separation; D065150:Cellular Reprogramming; D057137:DAX-1 Orphan Nuclear Receptor; D004268:DNA-Binding Proteins; D000071858:Epithelial Cell Adhesion Molecule; D00... | Nature | 2,015 | D015703:Antigens, CD; D000951:Antigens, Neoplasm; D015415:Biomarkers; D015815:Cell Adhesion Molecules; D057137:DAX-1 Orphan Nuclear Receptor; D004268:DNA-Binding Proteins; C519286:Dppa2 protein, mouse; D000071858:Epithelial Cell Adhesion Molecule; C513242:Etv5 protein, mouse; D018398:Homeodomain Proteins; D016256:Lewis... |
Validity and reliability of the Turkish version of the Maternal Antenatal Attachment Scale. | AIM
The objective of this study was to translate the Maternal Antenatal Attachment Scale (MAAS) into Turkish, to adapt it to Turkish cultural conditions, and to determine its validity and reliability.
METHODS
This study was conducted in a state hospital in the Central Anatolia Region, Sivas, Turkey. A total of 190 pr... | 10.1111/jjns.12052 | 24,962,076 | D000328:Adult; D005260:Female; D006783:Hospitals, State; D006801:Humans; D007231:Infant, Newborn; D009034:Mother-Child Relations; D011247:Pregnancy; D011795:Surveys and Questionnaires; D014421:Turkey; D055815:Young Adult | Japan journal of nursing science : JJNS | 2,015 | |
Homogeneous diet of contemporary Japanese inferred from stable isotope ratios of hair. | The globalization of food production and distribution has homogenized human dietary patterns irrespective of geography, but it is uncertain how far this homogenization has progressed. This study investigated the carbon and nitrogen isotope ratios in the scalp hair of 1305 contemporary Japanese and found values of -19.4... | 10.1038/srep33122 | 27,616,586 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D002247:Carbon Isotopes; D002648:Child; D002675:Child, Preschool; D004032:Diet; D005247:Feeding Behavior; D005260:Female; D006197:Hair; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007564:Japan; D008297:Male; ... | Scientific reports | 2,016 | D002247:Carbon Isotopes; D009587:Nitrogen Isotopes |
Survival Trends in Elderly Patients with Glioblastoma in the United States: a Population-based Study. | BACKGROUND/AIM
Concomitant and adjuvant temozolomide along with radiotherapy following surgery (the Stupp regimen) is the preferred therapy for young patients with glioblastoma as well as for elderly (>70 years) ones with favorable risk factors. This study investigated the survival trend since the introduction of the u... | 10.21873/anticanres.11052 | 27,630,344 | D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D003606:Dacarbazine; D005260:Female; D005909:Glioblastoma; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D016019:Survival Analysis; D000077204:Temozolomide | Anticancer research | 2,016 | D003606:Dacarbazine; D000077204:Temozolomide |
How ought we allocate unanticipated doses of COVID-19 vaccines? A proposal based on experience in the United States, 2020-2022. | With vaccination against COVID-19 well underway, providers in the United States (U.S.) found that vials of the Pfizer/BioNTech and Moderna vaccines contained more doses than listed. Because of limited vaccine shelf life, vaccine-providing institutions have thrown extra doses away or quickly distributed them using ad-ho... | 10.1057/s41271-022-00346-w | 35,379,920 | D000086382:COVID-19; D000086663:COVID-19 Vaccines; D006801:Humans; D014481:United States; D014611:Vaccination | Journal of public health policy | 2,022 | D000086663:COVID-19 Vaccines |
A Bias Toward Kindness Goals in Performance Feedback to Women (vs. Men). | While research has documented positivity biases in workplace feedback to women versus men, this phenomenon is not fully understood. We take a motivational perspective, theorizing that the gender stereotype of warmth shapes feedback givers' goals, amplifying the importance placed on kindness when giving critical feedbac... | 10.1177/01461672221088402 | 35,751,137 | D006801:Humans; D008297:Male; D005260:Female; D006040:Goals; D005246:Feedback; D063507:Sexism; D009042:Motivation; D013334:Students | Personality & social psychology bulletin | 2,023 | |
A novel piggyBac transposon inducible expression system identifies a role for AKT signalling in primordial germ cell migration. | In this work, we describe a single piggyBac transposon system containing both a tet-activator and a doxycycline-inducible expression cassette. We demonstrate that a gene product can be conditionally expressed from the integrated transposon and a second gene can be simultaneously targeted by a short hairpin RNA containe... | 10.1371/journal.pone.0077222 | 24,223,709 | D053687:Adult Stem Cells; D000818:Animals; D002460:Cell Line; D002465:Cell Movement; D002642:Chick Embryo; D002645:Chickens; D003001:Cloning, Molecular; D004251:DNA Transposable Elements; D053595:Embryonic Stem Cells; D005347:Fibroblasts; D015870:Gene Expression; D005818:Genetic Engineering; D005854:Germ Cells; D049452... | PloS one | 2,013 | D004251:DNA Transposable Elements; D049452:Green Fluorescent Proteins; D051057:Proto-Oncogene Proteins c-akt |
A study of symptom profile of depression following myocardial infarction. | Depression is common clinical manifestation following myocardial infarction (MI), the prevalence being 20.0-30.0% in different studies. Both biological factors and problems related to life threatening condition have been blamed as risk factors of depression following MI. Although the profile of symptomatology of depres... | 15,024,775 | D003863:Depression; D005500:Follow-Up Studies; D006801:Humans; D009203:Myocardial Infarction; D009390:Nepal; D011569:Psychiatric Status Rating Scales; D013997:Time Factors | Nepal Medical College journal : NMCJ | 2,003 | ||
Parental identification of rapists and pedophiles. | It is well documented that sex offenders experience a higher incidence of sexual abuse and are more likely to have been reared in dysfunctional families than are individuals in most comparison groups. It is unclear, however, whether growing up in an abusive or dysfunctional family affects the extent to which the potent... | 10.2466/pr0.1991.69.2.463 | 1,763,161 | D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D002650:Child Abuse, Sexual; D002675:Child, Preschool; D006801:Humans; D007062:Identification, Psychological; D007223:Infant; D008297:Male; D010287:Parent-Child Relations; D010290:Parents; D012742:Sex Offenses | Psychological reports | 1,991 | |
Movement-induced modulation of soleus H reflexes with altered length of biarticular muscles. | Passive pedaling movements of the leg results in the phasic modulation of the soleus H reflex of that leg. In contrast, the H reflex of the contralateral leg is attenuated tonically. The phasic modulation of the reflex ipsilaterally can be attributed to the afferent discharge associated with the cyclic lengthening of t... | 10.1016/s0006-8993(98)00246-7 | 9,622,587 | D000328:Adult; D004576:Electromyography; D006181:H-Reflex; D006621:Hip Joint; D006801:Humans; D007719:Knee Joint; D009068:Movement; D009119:Muscle Contraction; D018482:Muscle, Skeletal; D013979:Tibial Nerve | Brain research | 1,998 | |
Autoantibodies to type VII collagen have heterogeneous subclass and light chain compositions and their complement-activating capacities do not correlate with the inflammatory clinical phenotype. | Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus are blistering skin diseases characterized by IgG autoantibodies that predominantly target the noncollagenous domain 1 of type VII collagen, a skin basement membrane component. The basic immunologic events leading to the blistering processes in th... | 10.1023/a:1026451530967 | 11,202,231 | D001323:Autoantibodies; D003094:Collagen; D003171:Complement Pathway, Classical; D016107:Epidermolysis Bullosa Acquisita; D004848:Epithelium; D000939:Epitopes; D006801:Humans; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D008180:Lupus Erythematosus, Systemic; D010641:Phenotype; D017434:Protein Structu... | Journal of clinical immunology | 2,000 | D001323:Autoantibodies; D000939:Epitopes; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D011994:Recombinant Proteins; D003094:Collagen |
Morphometry of bladder carcinoma: I. The automatic delineation of urothelial nuclei in tissue sections using an IBAS II image array processor. | Semi-automatic methods of morphometry require the boundaries of the objects under study to be drawn by hand. This is slow, tedious and does not guarantee accuracy. Complete automation, with recognition, detection and verification by computer is not yet feasible. Automatic detection of nuclear boundaries with observer v... | 10.1002/path.1711530314 | 3,430,233 | D002467:Cell Nucleus; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D001743:Urinary Bladder; D001749:Urinary Bladder Neoplasms | The Journal of pathology | 1,987 | |
PlantExp: a platform for exploration of gene expression and alternative splicing based on public plant RNA-seq samples. | Over the last decade, RNA-seq has produced a massive amount of plant transcriptomic sequencing data deposited in public databases. Reanalysis of these public datasets can generate additional novel hypotheses not included in original studies. However, the large data volume and the requirement for specialized computation... | 10.1093/nar/gkac917 | 36,271,793 | D017398:Alternative Splicing; D018749:RNA, Plant; D000081246:RNA-Seq; D017423:Sequence Analysis, RNA; D012984:Software; D059467:Transcriptome; D010944:Plants | Nucleic acids research | 2,023 | D018749:RNA, Plant |
C1-esterase inhibitor blocks T lymphocyte proliferation and cytotoxic T lymphocyte generation in vitro. | We have previously shown that activated C1s complement and activated T cells cleave beta2-microglobulin (beta2m) in vitro leading to the formation of desLys58 beta2m. This process can specifically be inhibited by C1-esterase inhibitor (C1-inh). Furthermore we showed that exogenously added desLys58 beta2m in nanomolar a... | 10.1093/intimm/10.2.167 | 9,533,444 | D000818:Animals; D002478:Cells, Cultured; D003174:Complement C1 Inactivator Proteins; D003173:Complement C1s; D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D011480:Protease Inhibitors; D013602:T-Lymphocytes, ... | International immunology | 1,998 | D003174:Complement C1 Inactivator Proteins; D011480:Protease Inhibitors; D003173:Complement C1s |
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease. | Parkinson's disease is a neurodegenerative disorder with uncertain aetiology and ill-defined pathophysiology. Activated microglial cells in the substantia nigra (SN) are found in all animal models of Parkinson's disease and patients with the illness. Microglia may, however, have detrimental and protective functions in ... | 10.1093/brain/awn101 | 18,504,291 | D000818:Animals; D002478:Cells, Cultured; D003907:Dexamethasone; D004195:Disease Models, Animal; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005938:Glucocorticoids; D007375:Interleukin-1; D008070:Lipopolysaccharides; D008297:Male; D017628:Microglia; D009410:Nerve Degeneration; D009569:Nitri... | Brain : a journal of neurology | 2,008 | D005938:Glucocorticoids; D007375:Interleukin-1; D008070:Lipopolysaccharides; D009569:Nitric Oxide; D003907:Dexamethasone; D016627:Oxidopamine |
Vanilloid Receptor 1 Agonists, Capsaicin and Resiniferatoxin, Enhance MHC Class I-restricted Viral Antigen Presentation in Virus-infected Dendritic Cells. | DCs, like the sensory neurons, express vanilloid receptor 1 (VR1). Here we demonstrate that the VR1 agonists, capsaicin (CP) and resiniferatoxin (RTX), enhance antiviral CTL responses by increasing MHC class I-restricted viral antigen presentation in dendritic cells (DCs). Bone marrow-derived DCs (BM-DCs) were infected... | 10.4110/in.2016.16.4.233 | 27,574,502 | Immune network | 2,016 | ||
Pooling-analysis on hMLH1 polymorphisms and cancer risk: evidence based on 31,484 cancer cases and 45,494 cancer-free controls. | To elucidate the veritable relationship between three hMLH1 polymorphisms (rs1800734, rs1799977, rs63750447) and cancer risk, we performed this meta-analysis based on overall published data up to May 2017, from PubMed, Web of knowledge, VIP, WanFang and CNKI database, and the references of the original studies or revie... | 10.18632/oncotarget.21810 | 29,190,978 | Oncotarget | 2,017 | ||
The Association Between Multiple Abortions Within 1 Year and Previous Postabortal Desired Contraception at an Urban, Public Hospital. | To determine the proportion of women undergoing multiple abortions within 1 year at an urban, public hospital and the association with desired contraception after the index abortion. We conducted a retrospective analysis of all women undergoing abortion up to 13 weeks and 6 days gestation at Stroger Hospital from June... | 10.1089/jwh.2018.6944 | 30,394,817 | D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections; D003267:Contraception; D005260:Female; D006069:Gonorrhea; D006779:Hospitals, Public; D006801:Humans; D007434:Intrauterine Devices; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult | Journal of women's health (2002) | 2,019 | |
A comparison between health centre deliveries and deliveries born before arrival in the Aitape district. | In this survey the obstetric and neonatal data of the admissions to the Obstetric Ward in Raihu Health Centre during 1990, 1991 and the first half of 1992 were analyzed. The emphasis of the survey was on the difference between deliveries born before arrival (BBA) (24%) and health centre (HC) deliveries (76%). The surve... | 7,668,055 | D001724:Birth Weight; D036861:Delivery, Obstetric; D005260:Female; D005313:Fetal Death; D006268:Health Facilities; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008297:Male; D007744:Obstetric Labor Complications; D010219:Papua New Guinea; D006473:Postpartum Hemorrhage; D011247:Pregnancy | Papua and New Guinea medical journal | 1,994 | ||
Lifestyle factors associated with blood pressure control among those taking antihypertensive medication. | The purpose of this study was to explore the relations between lifestyle factors and blood pressure (BP) control among patients with hypertension who were regularly taking antihypertensive medication as prescribed. From the 2005 Korean National Health and Nutrition Examination Survey data, the 690 individuals diagnosed... | 10.1177/1010539509347941 | 19,825,840 | D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D006973:Hypertension; D008019:Life Style; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea; D055815:Young Adult | Asia-Pacific journal of public health | 2,011 | D000959:Antihypertensive Agents |
Comparative Genomics of the Major Histocompatibility Complex (MHC) of Felids. | This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered species. As such, the Felidae have the potential to be an informative m... | 10.3389/fgene.2022.829891 | 35,309,138 | Frontiers in genetics | 2,022 | ||
A parascalene technique of brachial plexus anesthesia. | A technique for brachial plexus anesthesia is described consisting of the injection of 20 ml of local anesthetic solution into the lower part of the posterior triangle of the neck at a point 1.5 to 2 cm above the clavicle at the lateral border of the anterior scalene muscle. The technique is simple, safe, and produced ... | 572,172 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000765:Anesthesia, Conduction; D001917:Brachial Plexus; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D009132:Muscles; D009333:Neck; D009407:Nerve Block | Anesthesia and analgesia | 1,979 | D008012:Lidocaine | |
Gastric asthma: a pathophysiological entity? | BACKGROUND
Gastro-oesophageal reflux disease (GORD) is manifested by typical reflux symptoms and atypical extra-oesophageal symptoms. Important in this respect are respiratory conditions. Gastric asthma is a prominent example of these extra-oesophageal manifestations of GORD. There is, however, much debate about its pr... | 10.1080/003655298750027164 | 9,515,747 | D018927:Anti-Asthmatic Agents; D001249:Asthma; D005764:Gastroesophageal Reflux; D006801:Humans | Scandinavian journal of gastroenterology. Supplement | 1,998 | D018927:Anti-Asthmatic Agents |
Altered levels of plasma chemokines in breast cancer and their association with clinical and pathological characteristics. | Chemokines are a family of small, structurally related cytokines with chemoattractant and activation properties. In breast cancer, both epithelial cancer cells and cells within the microenvironment secrete chemokines with either tumor-promoting or anti-malignant potential. The equilibrium between these two chemokine ac... | 10.4149/neo_2016_017 | 26,639,244 | D014408:Biomarkers, Tumor; D001943:Breast Neoplasms; D016022:Case-Control Studies; D018925:Chemokines; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009362:Neoplasm Metastasis; D011379:Prognosis; D015854:Up-Regulation | Neoplasma | 2,016 | D014408:Biomarkers, Tumor; D018925:Chemokines |
Impacts of the 2003 and 2015 summer heatwaves on permafrost-affected rock-walls in the Mont Blanc massif. | Rockfall is one of the main geomorphological processes that affects the evolution and stability of rock-walls. At high elevations, rockfall is largely climate-driven, very probably because of the warming of rock-wall permafrost. So with the ongoing global warming that drives the degradation of permafrost, the related h... | 10.1016/j.scitotenv.2017.07.055 | 28,735,090 | The Science of the total environment | 2,017 | ||
Purification and Characterization of Thermostable α-Amylase from Soil Bacterium Bacillus sp. | BACKGROUND
Amylases are used in several industrial and biotechnological sectors, including those producing textiles, detergents, paper and bakery products.
OBJECTIVE
This study aimed to purify an industrially important α-amylase from Bacillus sp. For this purpose, a single and rapid α-amylase purification was perform... | 10.2174/0929866528666211027113113 | 34,711,150 | D001407:Bacillus; D001426:Bacterial Proteins; D004795:Enzyme Stability; D006358:Hot Temperature; D012988:Soil Microbiology; D000516:alpha-Amylases | Protein and peptide letters | 2,021 | D001426:Bacterial Proteins; D000516:alpha-Amylases |
Three-dimensional carbon nanotube-textile anode for high-performance microbial fuel cells. | Microbial fuel cells (MFCs) harness the metabolism of microorganisms, converting chemical energy into electrical energy. Anode performance is an important factor limiting the power density of MFCs for practical application. Improving the anode design is thus important for enhancing the MFC performance, but only a littl... | 10.1021/nl103905t | 21,158,405 | D001672:Biocompatible Materials; D001674:Bioelectric Energy Sources; D004566:Electrodes; D004579:Electron Transport; D037742:Nanotubes, Carbon; D016062:Porosity; D013784:Textiles | Nano letters | 2,011 | D001672:Biocompatible Materials; D037742:Nanotubes, Carbon |
Factors associated with the likelihood of Giardia spp. and Cryptosporidium spp. in soil from dairy farms. | A study was conducted to identify factors associated with the likelihood of detecting Giardia spp. and Cryptosporidium spp. in the soil of dairy farms in a watershed area. A total of 37 farms were visited, and 782 soil samples were collected from targeted areas on these farms. The samples were analyzed for the presence... | 10.3168/jds.S0022-0302(03)73660-1 | 12,703,614 | D000383:Agriculture; D000818:Animals; D003458:Cryptosporidium; D003612:Dairying; D005872:Giardia; D006863:Hydrogen-Ion Concentration; D016015:Logistic Models; D012987:Soil | Journal of dairy science | 2,003 | D012987:Soil |
Persistent antibody and T cell responses induced by HIV-1 DNA vaccine delivered by electroporation. | Intramuscular needle injection of HIV-1 DNA vaccines typically elicits weak immune responses in immunized individuals. To improve such responses, the immunogenicity of a vaccine consisting of electroporated DNA followed by intramuscular protein boost was evaluated in rabbits and macaques. In macaques, electroporation o... | 10.1016/j.bbrc.2007.11.052 | 18,036,339 | D016915:AIDS Vaccines; D000818:Animals; D000906:Antibodies; D018274:Electroporation; D015497:HIV-1; D008252:Macaca fascicularis; D011817:Rabbits; D013601:T-Lymphocytes; D014162:Transfection; D019444:Vaccines, DNA | Biochemical and biophysical research communications | 2,008 | D016915:AIDS Vaccines; D000906:Antibodies; D019444:Vaccines, DNA |
[Stress-responsive systems in the rat pancreas upon long-term gastric hypochlorhydria and administration of multiprobiotic "Symbiter"]. | The intensity of free-radical processes upon long-term omeprazole-induced hypoacidity in the rat pancreas was investigated. Significant violation of oxidative-antioxidative balance in pancreatic tissue upon gastric hypochlorhydria was established: overproduction of superoxide anion, quantitative changes of lipid functi... | 23,808,312 | D000126:Achlorhydria; D000818:Animals; D000975:Antioxidants; D008054:Lipid Peroxides; D008297:Male; D009853:Omeprazole; D018384:Oxidative Stress; D010179:Pancreas; D019936:Probiotics; D051381:Rats; D013481:Superoxides | Ukrains'kyi biokhimichnyi zhurnal (1999 ) | 2,013 | D000975:Antioxidants; D008054:Lipid Peroxides; D013481:Superoxides; D009853:Omeprazole | |
Quasifree Neutron Knockout from ^{54}Ca Corroborates Arising N=34 Neutron Magic Number. | Exclusive cross sections and momentum distributions have been measured for quasifree one-neutron knockout reactions from a ^{54}Ca beam striking on a liquid hydrogen target at ∼200 MeV/u. A significantly larger cross section to the p_{3/2} state compared to the f_{5/2} state observed in the excitation of ^{53}Ca provi... | 10.1103/PhysRevLett.123.142501 | 31,702,209 | Physical review letters | 2,019 | ||
Disease-Associated SNPs in Inflammation-Related lncRNAs. | Immune-mediated diseases, such as celiac disease, type 1 diabetes or multiple sclerosis, are a clinically heterogeneous group of diseases that share many key genetic triggers. Although the pathogenic mechanisms responsible for the development of immune mediated disorders is not totally understood, high-throughput genom... | 10.3389/fimmu.2019.00420 | 30,906,297 | D005786:Gene Expression Regulation; D055106:Genome-Wide Association Study; D006801:Humans; D007154:Immune System Diseases; D007249:Inflammation; D020641:Polymorphism, Single Nucleotide; D062085:RNA, Long Noncoding | Frontiers in immunology | 2,019 | D062085:RNA, Long Noncoding |
Auditory-Motor Rhythms and Speech Processing in French and German Listeners. | Moving to a speech rhythm can enhance verbal processing in the listener by increasing temporal expectancies (Falk and Dalla Bella, 2016). Here we tested whether this hypothesis holds for prosodically diverse languages such as German (a lexical stress-language) and French (a non-stress language). Moreover, we examined t... | 10.3389/fpsyg.2017.00395 | 28,443,036 | Frontiers in psychology | 2,017 | ||
The International Diet-Health Index: a novel tool to evaluate diet quality for cardiometabolic health across countries. | INTRODUCTION
Diet is a major modifiable risk factor for cardiometabolic disease; however, interpretable measures capturing impacts of overall diet on health that can be easily used by policymakers at the global/national levels are not readily available.
METHODS
We developed the International Diet-Health Index (IDHI) ... | 10.1136/bmjgh-2019-002120 | 32,694,217 | D000328:Adult; D002318:Cardiovascular Diseases; D004032:Diet; D005260:Female; D014943:Global Health; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors | BMJ global health | 2,020 | |
A longitudinal study of marijuana effects. | One hundred regular marijuana users volunteered to be extensively interviewed in 1968-1970, and 97 were located and reinterviewed 6 to 8 years later. As part of each interview the subjects filled out a checklist review of 105 effects of marijuana. This report focuses on the differential patterns of effects found at the... | 10.3109/10826088509044290 | 4,044,081 | D000293:Adolescent; D000328:Adult; D000339:Affect; D002188:Cannabis; D003071:Cognition; D005260:Female; D006212:Hallucinations; D006801:Humans; D008297:Male; D009422:Nervous System Diseases; D011597:Psychomotor Performance; D012677:Sensation; D012725:Sexual Behavior; D012890:Sleep | The International journal of the addictions | 1,985 | |
Central corneal epitheliopathy in a long-term, overnight orthokeratology lens wearer: a case report. | PURPOSE
The purpose of this study is to report an unusual case of central corneal epitheliopathy (CCE) in a long-term orthokeratology lens wearer.
CASE REPORT
A single observational case report of a 12-year-old Chinese female myope with 3(1/2) years' experience in wearing orthokeratology lenses overnight was diagnose... | 10.1097/01.opx.0000236813.39603.49 | 17,041,315 | D002648:Child; D003261:Contact Lenses; D003316:Corneal Diseases; D019781:Corneal Topography; D019573:Epithelium, Corneal; D005260:Female; D006801:Humans; D009216:Myopia; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity | Optometry and vision science : official publication of the American Academy of Optometry | 2,006 | |
Energy conservation by Rhodothermus marinus respiratory complex I. | A sodium ion efflux, together with a proton influx and an inside-positive DeltaPsi, was observed during NADH-respiration by Rhodothermus marinus membrane vesicles. Proton translocation was monitored by fluorescence spectroscopy and sodium ion transport by (23)Na-NMR spectroscopy. Specific inhibitors of complex I (roten... | 10.1016/j.bbabio.2010.01.020 | 20,100,453 | D001426:Bacterial Proteins; D002462:Cell Membrane; D042967:Electron Transport Complex I; D004735:Energy Transfer; D017136:Ion Transport; D009682:Magnetic Resonance Spectroscopy; D009243:NAD; D010088:Oxidoreductases; D010100:Oxygen; D010101:Oxygen Consumption; D011190:Potassium Cyanide; D018892:Proton-Motive Force; D011... | Biochimica et biophysica acta | 2,010 | D001426:Bacterial Proteins; D011522:Protons; D012402:Rotenone; D009243:NAD; D012964:Sodium; D010088:Oxidoreductases; D042967:Electron Transport Complex I; D011190:Potassium Cyanide; D010100:Oxygen |
Remodelling of the normal incus. | Thirty normal incudes were examined using scanning electron microscopy (SEM) to assess the pattern and degree of bony remodelling. The body and short process appeared stable throughout life. By contrast, the lenticular and long processes demonstrated marked osteoclastic activity with a tendency to undergo progressive e... | 10.1111/j.1365-2273.1993.tb00820.x | 8,364,999 | D000293:Adolescent; D000328:Adult; D000368:Aged; D016723:Bone Remodeling; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007188:Incus; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged | Clinical otolaryngology and allied sciences | 1,993 | |
The results of B-scan ultrasonography in different positions after vitrectomy and gas tamponade. | PURPOSE
To determine the proper time frame in which to assess retinal attachment status and to evaluate the superior retinal attachment status by performing B-scan ultrasonography in different positions on patients who have undergone pars plana vitrectomy and gas tamoponade.
METHODS
In this prospective study, 23 pati... | 10.3341/kjo.2007.21.2.100 | 17,592,241 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000388:Air; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D012160:Retina; D012164:Retinal Diseases; D013997:Time Factors; D016896:Treatm... | Korean journal of ophthalmology : KJO | 2,007 | |
Access to preventive health care: is method of payment a barrier for immigrant Hispanic women? | This study describes the payment category of 397 low-income Hispanic women and the relationship to compliance with family planning visits the first year postbirth. Only one-fourth of the women returned for the one-year family planning visit, when they would have received well-woman care. Pay category was not a factor i... | 10.1016/s1049-3867(02)00130-5 | 12,015,185 | D000293:Adolescent; D000328:Adult; D003466:Cultural Characteristics; D004641:Emigration and Immigration; D005193:Family Planning Services; D018588:Fee-for-Service Plans; D005260:Female; D005382:Financing, Personal; D006297:Health Services Accessibility; D006779:Hospitals, Public; D006784:Hospitals, Teaching; D006801:Hu... | Women's health issues : official publication of the Jacobs Institute of Women's Health | 2,002 | |
Epidemiology and control of bovine herpesvirus 1 infection in Europe. | Bovine herpesvirus 1 (BHV-1) causes infectious bovine rhinotracheitis (IBR), infectious pustular vulvovaginitis, abortion and balanoposthitis, as well as neurological and systemic disease in cattle. The virus is endemic in cattle populations worldwide although in Europe six countries and several regions in other countr... | 24,954,868 | D000818:Animals; D002417:Cattle; D062665:Epidemiological Monitoring; D005060:Europe; D006566:Herpesviridae Infections; D007242:Herpesvirus 1, Bovine; D007241:Infectious Bovine Rhinotracheitis; D015995:Prevalence; D012307:Risk Factors | Veterinary journal (London, England : 1997) | 2,014 | ||
Recurrent Episodes of Some Mosquito-Borne Viral Diseases in Nigeria: A Systematic Review and Meta-Analysis. | Different ecological zones favor the breeding of Aedes species. The molecular epidemiology of dengue virus (DENV), yellow fever virus (YFV), and Chikungunya virus (CHIKV) was determined from outbreaks and surveillance activities in Nigeria. Twenty-eight DENV, twenty-five YFV, and two CHIKV sequences from Nigeria were r... | 10.3390/pathogens11101162 | 36,297,219 | Pathogens (Basel, Switzerland) | 2,022 | ||
Influence of curing protocol on selected properties of light-curing polymers: degree of conversion, volume contraction, elastic modulus, and glass transition temperature. | OBJECTIVES
The purpose of this study was to investigate the effect of light-curing protocol on degree of conversion (DC), volume contraction (C), elastic modulus (E), and glass transition temperature (T(g)) as measured on a model polymer. It was a further aim to correlate the measured values with each other.
METHODS
... | 10.1016/j.dental.2009.08.001 | 19,747,719 | D010129:4-Aminobenzoic Acid; D017438:Bisphenol A-Glycidyl Methacrylate; D002152:Calorimetry, Differential Scanning; D003188:Composite Resins; D055117:Curing Lights, Dental; D003764:Dental Materials; D055119:Elastic Modulus; D005898:Glass; D006801:Humans; D008027:Light; D008422:Materials Testing; D055595:Mechanical Phen... | Dental materials : official publication of the Academy of Dental Materials | 2,009 | D003188:Composite Resins; D003764:Dental Materials; D011108:Polymers; D011109:Polymethacrylic Acids; D013729:Terpenes; D062366:para-Aminobenzoates; C020946:triethylene glycol dimethacrylate; D011092:Polyethylene Glycols; D017438:Bisphenol A-Glycidyl Methacrylate; C048339:camphoroquinone; C030747:ethyl 4-dimethylaminobe... |
Selective estrogen-induced apoptosis in breast cancer. | Antihormone therapy remains the gold standard of care in the treatment of estrogen receptor (ER) positive breast cancer. However, development of acquired long term antihormone resistance exposes a vulnerability to estrogen that induces apoptosis. Laboratory and clinical studies indicate that successful therapy with est... | 24,929,046 | D017209:Apoptosis; D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D004958:Estradiol; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D061986:MCF-7 Cells; D011960:Receptors, Estrogen | Steroids | 2,014 | D011960:Receptors, Estrogen; D004958:Estradiol | |
The gas-phase ozonolysis of beta-caryophyllene (C(15)H(24)). Part I: an experimental study. | The gas phase reaction of ozone with beta-caryophyllene was investigated in a static glass reactor at 750 Torr and 296 K under various experimental conditions. The reactants and gas phase products were monitored by FTIR-spectroscopy and proton-transfer-reaction mass spectrometry (PTR-MS). Aerosol formation was monitore... | 10.1039/b817824k | 19,458,818 | D002245:Carbon Dioxide; D002248:Carbon Monoxide; D003510:Cyclohexanes; D005557:Formaldehyde; D016166:Free Radical Scavengers; D006861:Hydrogen Peroxide; D017665:Hydroxyl Radical; D013058:Mass Spectrometry; D010126:Ozone; D000081223:Polycyclic Sesquiterpenes; D011522:Protons; D012717:Sesquiterpenes; D017550:Spectroscopy... | Physical chemistry chemical physics : PCCP | 2,009 | D003510:Cyclohexanes; D016166:Free Radical Scavengers; D000081223:Polycyclic Sesquiterpenes; D011522:Protons; D012717:Sesquiterpenes; D002245:Carbon Dioxide; D005557:Formaldehyde; D017665:Hydroxyl Radical; C506365:Cyclohexane; D010126:Ozone; D002248:Carbon Monoxide; D006861:Hydrogen Peroxide; C024714:caryophyllene |
High Spatial Resolution Thermal Mapping of Volatile Switching in NbO-Based Memristor Using In Situ Scanning Thermal Microscopy. | Temperature mapping by in situ thermoreflectance thermal imaging (TRTI) or midwave infrared spectroscopy has played an important role in understanding the origins of threshold switching and the effect of insulator-metal transitions in oxide-based memrsitive devices. In this study, we use scanning thermal microscopy (ST... | 10.1021/acsami.2c06870 | 35,700,145 | ACS applied materials & interfaces | 2,022 | ||
Risk factors associated with COVID-19 in systemic lupus erythematosus: Results from a longitudinal prospective cohort. | INTRODUCTION
Patients with SLE (systemic lupus erythematosus) have a higher risk of infection due to dysregulated immune system as well as long-term use of immunosuppressants (IS). This could influence the risk of COVID-19 and its outcome.
METHODS
We conducted a longitudinal prospective study across 15 rheumatology c... | 10.1177/09612033231155837 | 36,731,873 | D006801:Humans; D008297:Male; D008180:Lupus Erythematosus, Systemic; D011446:Prospective Studies; D000086382:COVID-19; D008137:Longitudinal Studies; D007166:Immunosuppressive Agents; D012307:Risk Factors | Lupus | 2,023 | D007166:Immunosuppressive Agents |
VGLL3 expression is associated with macrophage infiltration and predicts poor prognosis in epithelial ovarian cancer. | Background/objective
High-grade serous ovarian carcinoma (HGSOC) is the most common histologic type of epithelial ovarian cancer (EOC). Due to its poor survival outcomes, it is essential to identify novel biomarkers and therapeutic targets. The hippo pathway is crucial in various cancers, including gynaecological cance... | 10.3389/fonc.2023.1152991 | 37,342,190 | Frontiers in oncology | 2,023 | ||
[Improved analysis of left ventricular function using three-dimensional echocardiography]. | Left ventricular geometry and function are important pathophysiologic and prognostic parameters. However, especially in patients with cardiac pathologies left ventricular geometry can be complex. Quantification of left ventricular volumes using conventional two-dimensional echocardiography is only possible when simplif... | 10.1007/s00392-005-1409-5 | 16,416,061 | D002306:Cardiac Volume; D003287:Contrast Media; D019560:Echocardiography, Three-Dimensional; D017548:Echocardiography, Transesophageal; D004699:Endocardium; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D018487:Ventric... | Zeitschrift fur Kardiologie | 2,005 | D003287:Contrast Media |
EGFR inhibitors, MHC expression and immune responses : Can EGFR inhibitors be used as immune response modifiers? | A recent study from our laboratory demonstrated that epidermal growth factor receptor (EGFR) inhibitors (EGFRIs) augment the expression of class I and class II MHC molecules. This finding provides an additional mechanism through which EGFRIs may exert anti-tumor effects and supports the notion that EGFRIs may influence... | 10.4161/onci.1.1.18073 | 22,720,215 | Oncoimmunology | 2,012 | ||
Xenoreactive CD4+ memory T cells resist inhibition by anti-CD44 mAb and reject islet grafts via a Th2-dependent pathway. | BACKGROUND
Memory T cells are a significant barrier to the induction of transplant tolerance. Our previous study demonstrated that multiple applications of anti-CD44 monoclonal antibody (mAb) could significantly inhibit CD4(+) memory T cells from mediating rejection of cardiac allografts. Now, we sought to explore the ... | 10.1111/j.1399-3089.2011.00646.x | 21,848,543 | D000818:Animals; D000911:Antibodies, Monoclonal; D015704:CD4 Antigens; D015496:CD4-Positive T-Lymphocytes; D049109:Cell Proliferation; D003921:Diabetes Mellitus, Experimental; D005260:Female; D006085:Graft Survival; D018960:Hyaluronan Receptors; D016381:Islets of Langerhans Transplantation; D051379:Mice; D008807:Mice, ... | Xenotransplantation | 2,011 | D000911:Antibodies, Monoclonal; D015704:CD4 Antigens; D018960:Hyaluronan Receptors |
Unilateral duplex horseshoe kidney with ectopic ureterocele. | We have reported a case of horseshoe kidney, a common renal fusion anomaly. Because of the 25% incidence of associated genitourinary anomalies, we believe that the diagnosis of horseshoe kidney in pediatric patients should initiate a thorough urologic evaluation, including intravenous urography and real-time sonography... | 10.1097/00007611-198502000-00021 | 3,883,510 | D002675:Child, Preschool; D006801:Humans; D007668:Kidney; D008297:Male; D011859:Radiography; D014463:Ultrasonography; D014518:Ureterocele; D014521:Urethra; D001743:Urinary Bladder | Southern medical journal | 1,985 | |
Embedded, engaged, evolving: a consortium of nurse researchers and clinicians. | This article describes the journey of an innovative partnership among nurse researchers and nurse clinicians. The Chronic Illness Consortium (CIC) is an academic-service partnership between a university and its neighbors in a region without an academic medical center. It began with a small group of nurse researchers se... | 10.1016/j.outlook.2007.01.001 | 17,386,311 | D002908:Chronic Disease; D002983:Clinical Competence; D003142:Communication; D003299:Cooperative Behavior; D004059:Diffusion of Innovation; D006801:Humans; D007373:Interinstitutional Relations; D007400:Interprofessional Relations; D019359:Knowledge; D008404:Massachusetts; D016294:Models, Nursing; D017146:Models, Organi... | Nursing outlook | 2,007 | |
Quantitative in vivo microscopy: the return from the 'omics'. | The confluence of recent advances in microscopy instrumentation and image analysis, coupled with the widespread use of GFP-like proteins as reporters of gene expression, has opened the door to high-throughput in vivo studies that can provide the morphological and temporal context to the biochemical pathways regulating ... | 10.1016/j.copbio.2006.07.005 | 16,899,361 | D000818:Animals; D001695:Biology; D049452:Green Fluorescent Proteins; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D053858:Metabolic Networks and Pathways; D008856:Microscopy, Fluorescence | Current opinion in biotechnology | 2,006 | D049452:Green Fluorescent Proteins |
Thiazolidine based fluorescent chemosensors for aluminum ions and their applications in biological imaging. | Utilization of fluorescent techniques in detection of various metal ions actively pursued allow ultrasensitive and selective detections of metal ions and prevent the adverse effect of cations such as aluminum (III) ions. In this study, two novel fluorescent chemosensors containing thiazole derivatives, ((E)-2-(4-hydrox... | 10.1016/j.saa.2020.118431 | 32,413,718 | D000535:Aluminum; D002460:Cell Line; D005456:Fluorescent Dyes; D006801:Humans; D008856:Microscopy, Fluorescence; D008958:Models, Molecular; D061848:Optical Imaging; D053778:Thiazolidines | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | 2,020 | D005456:Fluorescent Dyes; D053778:Thiazolidines; D000535:Aluminum |
Automated refinement and inference of analytical models for metabolic networks. | The reverse engineering of metabolic networks from experimental data is traditionally a labor-intensive task requiring a priori systems knowledge. Using a proven model as a test system, we demonstrate an automated method to simplify this process by modifying an existing or related model--suggesting nonlinear terms and ... | 10.1088/1478-3975/8/5/055011 | 21,832,805 | D000465:Algorithms; D019295:Computational Biology; D006019:Glycolysis; D007700:Kinetics; D053858:Metabolic Networks and Pathways; D008954:Models, Biological; D017711:Nonlinear Dynamics; D015003:Yeasts | Physical biology | 2,011 | |
The Prevalence and Spectrum of α-Thalassemia in Guizhou Province of South China. | α-Thalassemia (α-thal) is one of the most prevalent genetic diseases in the world and is especially frequent in tropical and subtropical regions, including South China. The aim of this study was to investigate the prevalence and spectrum of α-thal in Guizhou Province as this information was unknown. A total of 40 α-tha... | 10.3109/03630269.2015.1041037 | 26,193,976 | D000483:Alleles; D002681:China; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D005843:Geography; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D015995:Prevalence; D055542:alpha-Globins; D017085:alpha-Thalassemia | Hemoglobin | 2,015 | D055542:alpha-Globins |
Immunolocalization and expression of kinin B1R and B2R receptors in human inflammatory bowel disease. | Bradykinin is a mediator of inflammation, responsible for pain, vasodilation, and capillary permeability. Bradykinin receptor 1 (B(1)R) and bradykinin receptor 2 (B(2)R) are G protein-coupled receptors that mediate kinin effects. The latter is constitutive and rapidly desensitized; the former is induced by inflammatory... | 10.1152/ajpgi.00369.2004 | 15,805,101 | D000328:Adult; D000906:Antibodies; D003093:Colitis, Ulcerative; D003424:Crohn Disease; D005260:Female; D015870:Gene Expression; D006801:Humans; D007150:Immunohistochemistry; D007422:Intestines; D008297:Male; D008875:Middle Aged; D012333:RNA, Messenger; D043783:Receptor, Bradykinin B1; D043782:Receptor, Bradykinin B2 | American journal of physiology. Gastrointestinal and liver physiology | 2,005 | D000906:Antibodies; D012333:RNA, Messenger; D043783:Receptor, Bradykinin B1; D043782:Receptor, Bradykinin B2 |
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. | An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused functional ... | 10.1016/j.chom.2020.02.001 | 32,035,028 | D019943:Amino Acid Substitution; D000073640:Betacoronavirus; D000086382:COVID-19; D002681:China; D018352:Coronavirus Infections; D016679:Genome, Viral; D065207:Middle East Respiratory Syndrome Coronavirus; D058873:Pandemics; D010802:Phylogeny; D011024:Pneumonia, Viral; D045473:Severe acute respiratory syndrome-related ... | Cell host & microbe | 2,020 | |
The use of different measurements and definitions of periodontal disease in the study of the association between periodontal disease and risk of myocardial infarction. | BACKGROUND
The role of periodontal disease as an independent risk factor for cardiovascular disease (CVD) has been under debate because of the inconsistency of findings across studies. One of the major issues is the method used to assess or define periodontal disease. The present study assesses if the observed associat... | 10.1902/jop.2006.050276 | 16,734,583 | D000328:Adult; D000368:Aged; D000539:Alveolar Process; D003327:Coronary Disease; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D017622:Periodontal Attachment Loss; D010510:Periodontal Diseases; D012307:Risk Factors; D016388:Tooth Loss | Journal of periodontology | 2,006 | |
Beneficial effects of pioglitazone on left ventricular hypertrophy in genetically hypertensive rats. | Beneficial effects of thiazolidinediones, peroxisome proliferator-activated receptor gamma (PPARgamma) agonists, on cardiovascular injuries have been reported. However, the effects of these agonists on left ventricular (LV) hypertrophy have not been clarified. To investigate whether pioglitazone improves LV hypertrophy... | 10.1291/hypres.30.863 | 18,037,780 | D000818:Animals; D001786:Blood Glucose; D001794:Blood Pressure; D024042:Collagen Type I; D024061:Collagen Type III; D055513:Connective Tissue Growth Factor; D004452:Echocardiography; D006973:Hypertension; D017379:Hypertrophy, Left Ventricular; D007004:Hypoglycemic Agents; D017874:Immediate-Early Proteins; D007328:Insul... | Hypertension research : official journal of the Japanese Society of Hypertension | 2,007 | D001786:Blood Glucose; C526316:CCN2 protein, rat; D024042:Collagen Type I; D024061:Collagen Type III; D007004:Hypoglycemic Agents; D017874:Immediate-Early Proteins; D007328:Insulin; D036341:Intercellular Signaling Peptides and Proteins; D047495:PPAR gamma; D012333:RNA, Messenger; D017382:Reactive Oxygen Species; D04516... |
Effects of leptin and leukemia inhibitory factor on preimplantation development and STAT3 signaling of mouse embryos in vitro. | Preimplantation mouse embryos simultaneously express receptors for leptin and leukemia inhibitory factor (LIF), both of which trigger activation of STAT3 (Signal Transducer and Activator of Transcription) protein. To examine the joint effects of leptin and LIF on embryonic development, we studied preimplantation develo... | 10.1095/biolreprod.103.019034 | 12,826,573 | D016475:3T3 Cells; D000818:Animals; D017209:Apoptosis; D001755:Blastocyst; D053938:DNA Fragmentation; D004268:DNA-Binding Proteins; D004789:Enzyme Activation; D005260:Female; D005455:Fluorescent Antibody Technique; D015850:Interleukin-6; D020738:Leptin; D053605:Leukemia Inhibitory Factor; D053680:Leukemia Inhibitory Fa... | Biology of reproduction | 2,003 | D004268:DNA-Binding Proteins; D015850:Interleukin-6; D020738:Leptin; D053605:Leukemia Inhibitory Factor; D053680:Leukemia Inhibitory Factor Receptor alpha Subunit; C507838:Lif protein, mouse; C507841:Lifr protein, mouse; D011956:Receptors, Cell Surface; D018121:Receptors, Cytokine; D054411:Receptors, Leptin; D053606:Re... |
Clinical and blood rheologic stability in erythropoietin-treated predialysis patients. | We assessed human recombinant erythropoietin (rHuEPO) as treatment for anemia in azotemic patients who did not require dialytic therapy. The study group consisted of 5 azotemic men and 5 women (mean serum creatinine concentration 5.2 +/- 3.2 mg/dl) whose mean hematocrit was 27.4 + 3.0%. Of these, 5 subjects had diabeti... | 10.1159/000168214 | 2,260,615 | D000328:Adult; D000368:Aged; D000740:Anemia; D001809:Blood Viscosity; D003928:Diabetic Nephropathies; D004921:Erythropoietin; D005260:Female; D006400:Hematocrit; D006801:Humans; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D006435:Renal Dialysis; D014511:Uremia | American journal of nephrology | 1,990 | D011994:Recombinant Proteins; D004921:Erythropoietin |
Comparison between fixed-angle and customised corneal-polarisation compensation methods in scanning laser polarimetric measurement of the retinal nerve fibre layer in glaucoma. | PURPOSE
To investigate the differences between the results of scanning laser polarimetric (SLP) measurements of the retinal nerve fibre layer thickness (RNFLT) made using two different corneal-polarisation techniques; customised (SLP-C), and fixed-angle (SLP-F) compensations.
METHODS
Both SLP-C and SLP-F were perform... | 10.1038/sj.eye.6701429 | 15,184,959 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea; D003430:Cross-Sectional Studies; D003941:Diagnostic Techniques, Ophthalmological; D005902:Glaucoma, Open-Angle; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007834:Lasers; D008875:Middle Aged; D009412:Nerve Fibers; D012165:Retinal ... | Eye (London, England) | 2,005 | |
Real-space visualization of sequential debromination of polybrominated benzenes on Ag(111). | By a combination of scanning tunneling microscopy imaging and density functional theory calculations, dehalogenation processes of symmetric polyhalogenated benzenes were explored on Ag(111), and a series of intermediate states were captured and visualized in real space. These results reveal a sequential dehalogenation ... | 10.1039/d2cc05876f | 36,537,623 | Chemical communications (Cambridge, England) | 2,023 | ||
[On the chemistry of etofenamate, a novel anti-inflammatory agent from the series of N-arylanthranilic acid derivatives (author's transl)]. | Etofenamate is 2-(2-hydroxyethoxy)ethyl-N-(a,a,a,-trifluorom-tolyl)anthranilate and has been selected as an antiphlogistic agent for percutaneous therapy. Its characteristic alcohol-ether-ester structure brings about an increase in lipophilia and in its ability to penetrate through the intact skin. Furthermore, its oil... | 579,118 | D000284:Administration, Oral; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005439:Flufenamic Acid; D007202:Indicators and Reagents; D051381:Rats; D012869:Skin Absorption | Arzneimittel-Forschung | 1,977 | D007202:Indicators and Reagents; D005439:Flufenamic Acid | |
Markov State Model of Ion Assembling Process. | We study the process of ion assembling in aqueous solution by means of molecular dynamics. In this article, we present a method to study many-particle assembly using the Markov state model formalism. We observed that at NaCl concentration higher than 1.49 mol/kg, the system tends to form a big ionic cluster composed of... | 10.1021/acs.jpca.5b11650 | 27,101,432 | The journal of physical chemistry. A | 2,016 | ||
Somato-sympathetic response with the extremely high latency in unanesthetized decerebrate frog. | Excitation of the sciatic nerve A-afferents in the immobilized unanesthetized decerebrated frog was found to evoke two responses in the postganglionic sympathetic efferent nerves as well as in the preganglionic ones. The first response with a latency not more than 150 ms consists of an excitatory and an inhibitory comp... | 10.1016/0165-1838(86)90053-6 | 3,486,203 | D000818:Animals; D003243:Consciousness; D003655:Decerebrate State; D008297:Male; D011896:Rana temporaria; D011930:Reaction Time; D012018:Reflex; D013564:Sympathetic Nervous System | Journal of the autonomic nervous system | 1,986 | |
Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. | The SSN3 and SSN8 genes of Saccharomyces cerevisiae were identified by mutations that suppress a defect in SNF1, a protein kinase required for release from glucose repression. Mutations in SSN3 and SSN8 also act synergistically with a mutation of the MIG1 repressor protein to relieve glucose repression. We have cloned ... | 10.1073/pnas.92.9.4006 | 7,732,022 | D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D056850:Cyclin-Dependent Kinase 8; D018844:Cyclin-Dependent Kinases; D016213:Cyclins; D017931:DNA Primers; D004268:DNA-Binding Proteins; D004330:Drosophila; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal;... | Proceedings of the National Academy of Sciences of the United States of America | 1,995 | D016213:Cyclins; D017931:DNA Primers; D004268:DNA-Binding Proteins; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; C093345:SSN8 protein, S cerevisiae; D017346:Protein Serine-Threonine Kinases; D056850:Cyclin-Dependent Kinase 8; D018844:Cyclin-Dependent Kinases; C498309:SSN3 protein, S cerevis... |
Adrenal ganglioneuroma in a patient presenting with severe hypertension and diarrhea. | Ganglioneuromas (GNs) are neural crest cell-derived tumors and rarely occur in the adrenal gland. There are presently no markers that can reliably distinguish benign and malignant neuroendocrine tumors. Here we describe a 63-year-old woman who developed sudden chest pain and hypertension combined with increased stool f... | 10.1677/erc.0.0100099 | 12,653,673 | D000310:Adrenal Gland Neoplasms; D002878:Chromosomes, Human, Pair 1; D002886:Chromosomes, Human, Pair 17; D003967:Diarrhea; D005260:Female; D005729:Ganglioneuroma; D006801:Humans; D006973:Hypertension; D007124:Immunoenzyme Techniques; D019656:Loss of Heterozygosity; D008279:Magnetic Resonance Imaging; D008875:Middle Ag... | Endocrine-related cancer | 2,003 | D014660:Vasoactive Intestinal Peptide |
Strategic placement of bedside ventriculostomies using ultrasound image guidance: report of three cases. | BACKGROUND
The blind free-hand technique for external ventricular drain (EVD) placement sometimes requires multiple attempts, and catheter location is often less than ideal. Our institution has adapted an intraoperative ultrasound-guided ventriculostomy technique for the placement of EVDs at the bedside. Our experience... | 10.1007/s12028-011-9571-2 | 21,691,896 | D000368:Aged; D002404:Catheterization; D002543:Cerebral Hemorrhage; D004322:Drainage; D004453:Echoencephalography; D005260:Female; D006801:Humans; D006849:Hydrocephalus; D008297:Male; D008875:Middle Aged; D014696:Ventriculostomy | Neurocritical care | 2,012 | |
Complete Genome Sequence of "Candidatus Liberibacter africanus," a Bacterium Associated with Citrus Huanglongbing. | We report here the complete genome sequence of "Candidatus Liberibacter africanus" strain PTSAPSY. The 1,192,232-bp genome with 34.5% G+C content comprises 1,017 open reading frames, 44 tRNAs, and three complete rRNAs in a circular chromosome. | 26,184,931 | Genome announcements | 2,015 |
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