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24330549 | Likely Introduction Date of Schmallenberg Virus into France According to Monthly Serological Surveys in Cattle. | To estimate the date of introduction of Schmallenberg virus (SBV) into France, the prevalence of antibodies against the virus was determined monthly in cattle from two northern departments from August 2011 to April 2012. Seropositive cattle were detected from October 2011 in both departments with a prevalence of 55.6% ... | [
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"Antibodies, Viral",
"Bunyaviridae Infections",
"Cattle",
"Cattle Diseases",
"Dairying",
"Female",
"France",
"Orthobunyavirus",
"Prevalence",
"Seasons",
"Seroepidemiologic Studies",
"Surveys and Questionnaires"
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6871017 | The Australian High and Low avoidance rat strains: differential effects of ethanol and alpha-methyl-p-tyrosine. | Two new lines of rats have been selectively bred for high or low active avoidance responding--the Australian High (AHA) and Low (ALA) Avoiders. Ethanol (1-1.5 g/kg body weight, i.p.) improved acquisition of active avoidance responding only in ALA, whereas alpha-methyl-p-tyrosine (AMPT; 80 mg/kg body weight, i.p.) seeme... | [
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"alpha-Methyltyrosine"
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19605892 | Rectal plasmacytoma with intracellular hemosiderin in a dog. | An 11-year-old female American Cocker Spaniel was presented with a rectal mass that protruded through the anus. Cytologically, the mass was composed of neoplastic round cells consistent with an extramedullary plasmacytoma. Histiocytic sarcoma, carcinoid tumor, and melanoma were also considered because of the presence o... | [
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"Dog Diseases",
"Dogs",
"Female",
"Hemosiderin",
"Plasmacytoma",
"Rectal Neoplasms"
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28256305 | The effects of KinesioTape on the treatment of lateral epicondylitis. | STUDY DESIGN: Randomized clinical trial.INTRODUCTION: KinesioTape (KT) is a noninvasive method to treat pain and muscular dysfunction.PURPOSE: To investigate the effect of KT with and without tension on pain intensity, pain pressure threshold, grip strength and disability in individuals with lateral epicondylitis, and ... | [
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"Pain Measurement",
"Tennis Elbow",
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30797136 | Tuberlatum coatsi gen. n., sp. n. (Alveolata, Perkinsozoa), a New Parasitoid with Short Germ Tubes Infecting Marine Dinoflagellates. | Perkinsozoa is an exclusively parasitic group within the alveolates and infections have been reported from various organisms, including marine shellfish, marine dinoflagellates, freshwater cryptophytes, and tadpoles. Despite its high abundance and great genetic diversity revealed by recent environmental rDNA sequencing... | [
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"Alveolata",
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"RNA, Algal",
"RNA, Protozoan",
"Republic of Korea",
"Sequence Analysis, RNA"
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17316383 | Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo. | The mammalian node, the functional equivalent of the frog dorsal blastoporal lip (Spemann's organizer), was originally described by Viktor Hensen in 1876 in the rabbit embryo as a mass of cells at the anterior end of the primitive streak. Today, the term "node" is commonly used to describe a bilaminar epithelial groove... | [
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12695292 | Preference toward a T-helper type 1 response in patients with coronary spastic angina. | BACKGROUND: Coronary artery spasm plays an important role in the pathogenesis of ischemic heart diseases such as unstable angina (UA) and acute myocardial infarction. Nitric oxide (NO) plays an important role in coronary artery spasm. We previously reported a deficiency in NO activity in the spasm arteries of patients ... | [
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29739582 | The critical micelle concentration of lecithin in bulk oils and medium chain triacylglycerol is influenced by moisture content and total polar materials. | Effects of different moisture contents and oxidised compounds on the critical micelle concentration (CMC) of lecithin were determined in bulk oils and in medium-chain triacylglycerols (MCT). CMC of lecithin in MCT was significantly higher than that in other vegetable oils including olive, soybean, corn, and rapeseed oi... | [
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30657055 | Fears and beliefs of people living with rheumatoid arthritis: a systematic literature review. | OBJECTIVE: To assess the main fears and beliefs of people with rheumatoid arthritis (RA) and their effect on treatment outcomes; METHODS: A systematic literature review was conducted in Pubmed/Medline; original articles published up to May 2017, reporting fears and/or beliefs of adult patients with RA were analyzed. Fe... | [
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"Arthritis, Rheumatoid",
"Fatigue",
"Fear",
"Female",
"Health Knowledge, Attitudes, Practice",
"Humans",
"Male",
"Middle Aged",
"Pain",
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"Quality of Life",
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11414087 | Effectiveness of endothelial cell seeding on patency of damaged vascular surfaces in a canine model. | The effects of endothelial cell seeding, which is assumed to be an effective technique to improve patency rates of denuded vascular surfaces, were investigated in an experimental model. In this study, after anesthetic induction, jugular veins of 16 dogs were harvested bilaterally. Endothelial cells were extracted enzym... | [
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"Female",
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"Vascular Patency"
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1107676 | Studies on the primary structure of 14 proteins from the large subunit of Escherichia coli ribosomes with an improved protein sequenator and with mass spectrometry. | Fourteen proteins from the large subunit of Escherichia coli ribosomes were analyzed in an improved sequenator. In addition to our previously described modifications of a Beckman sequenator, new valves which work free of a dead volume were constructed. By this and the previous improvements (e.g., a new vacuum system wi... | [
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"Bacterial Proteins",
"Chromatography, Gas",
"Chromatography, Thin Layer",
"Escherichia coli",
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20492370 | Maternal tamoxifen treatment alters oocyte differentiation in the neonatal mice: inhibition of oocyte development and decreased folliculogenesis. | AIM: Primary germ cells after migration to the developing ovary differentiate to oogonia and oocytes. The formation and number of primordial follicles in early fetal life are determining factors in the fertility state of adult life. Tamoxifen is used both to stimulate ovulation and as an anticancer drug. The aim of the... | [
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"Oocytes",
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23722674 | Corneal endothelial safety following subconjunctival and intrastromal injection of bevacizumab for corneal neovascularization. | The purpose of this study is to determine the effect on endothelial cell density and morphology of combined subconjunctival and intracorneal injection of bevacizumab for the treatment of corneal neovascularization (NV). The charts and specular microscopy images of ten consecutive patients with corneal NV, who received ... | [
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26331807 | Drug-eluting beads versus conventional chemoembolization for the treatment of unresectable hepatocellular carcinoma. | BACKGROUND AND AIM: Solid demonstrations of superior efficacy of drug-eluting beads transarterial chemoembolization with respect to conventional chemoembolization in hepatocellular carcinoma patients are lacking. The aim of the study was to compare these two techniques in two large cohorts of unresectable hepatocellula... | [
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2160222 | Inactivation of human and simian rotaviruses by chlorine dioxide. | The inactivation of single-particle stocks of human (type 2, Wa) and simian (SA-11) rotaviruses by chlorine dioxide was investigated. Experiments were conducted at 4 degrees C in a standard phosphate-carbonate buffer. Both virus types were rapidly inactivated, within 20 s under alkaline conditions, when chlorine dioxid... | [
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25045788 | Clinical outcomes and patterns of failure in pineoblastoma: a 30-year, single-institution retrospective review. | OBJECTIVE: To update outcomes and assess prognostic factors in the modern, multimodality treatment of patients with pineoblastoma.METHODS: The medical records of patients with pineoblastoma evaluated at the M.D. Anderson Cancer Center between 1982 and 2012 were reviewed retrospectively.RESULTS: Thirty-one patients with... | [
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11008167 | Differential regulation of adult and embryonic glutamate decarboxylases in rat dentate granule cells after kainate-induced limbic seizures. | In adult brain, the inhibitory GABAergic neurons utilize two distinct molecular forms of the GABA-synthesizing enzyme glutamate decarboxylase (GAD), GAD65 and GAD67. During embryonic development, two truncated forms of GAD67 are also expressed (GAD25 and GAD44), which are translated from two embryonic-specific splice v... | [
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"RNA, Messenger",
"Rats",
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30304714 | Randomized Trial Comparing Proactive, High-Dose versus Reactive, Low-Dose Intravenous Iron Supplementation in Hemodialysis (PIVOTAL): Study Design and Baseline Data. | BACKGROUND: Intravenous (IV) iron supplementation is a standard maintenance treatment for hemodialysis (HD) patients, but the optimum dosing regimen is unknown.METHODS: PIVOTAL (Proactive IV irOn Therapy in hemodiALysis patients) is a multicenter, open-label, blinded endpoint, randomized controlled (PROBE) trial. Incid... | [
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29712788 | Mesocorticolimbic Connectivity and Volumetric Alterations in DCC | The axon guidance cue receptor DCC (deleted in colorectal cancer) plays a critical role in the organization of mesocorticolimbic pathways in rodents. To investigate whether this occurs in humans, we measured (1) anatomical connectivity between the substantia nigra/ventral tegmental area (SN/VTA) and forebrain targets, ... | [
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21814157 | IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis. | Mechanisms underlying the increased risk of recurrent wheeze after respiratory syncytial virus lower respiratory tract infection (RSV LRTI) are unclear. Specifically, information about genetic determinants of recurrent wheeze after RSV LRTI is limited. We performed a candidate gene association study to identify genetic... | [
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2286318 | [Prevention of vaginal prolapse in hysterectomy by suspension of the vaginal stump]. | For prophylaxis of enterocele and of prolapse of the vagina following hysterectomy, the vaginal stump is fixed in at-risk patients to the sacro-uterine ligaments (known as McCall's suture) or to the sacro-spinal ligament (Amreich-Richter method). We report on the indications and results obtained in 101 sacro-spinal fix... | [
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12431114 | Nitrosyliron(III) porphyrinates: porphyrin core conformation and FeNO geometry. Any correlation? | The synthesis, structural, and spectroscopic characterization of (nitrosyl)iron(III) porphyrinate complexes designed to have strongly nonplanar porphyrin core conformations is reported. The species have a nitrogen-donor axial ligand trans to the nitrosyl ligand and display planar as well as highly nonplanar porphyrin c... | [
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6374421 | A practical approach to diagnosis of swine diseases. | Blood samples from the vena cava or jugular vein should be chilled but not frozen, and serum chilled or frozen. Tissue specimens for bacteriologic or virologic examination should be chilled in individual plastic bags and frozen if not submitted immediately. Live pigs should be submitted for TGE studies. Tissue specimen... | [
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8879184 | Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor. | Transgenic mice expressing transforming growth factor alpha (TGF-alpha) in type II cells under control of the lung-specific surfactant protein-C (SP-C) promoter develop pulmonary fibrosis and marked airspace hypoplasia. To identify cellular signaling mechanisms involved in lesion formation, we generated transgenic mice... | [
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24723392 | Differential presentation of endogenous and exogenous hepatitis B surface antigens influences priming of CD8(+) T cells in an epitope-specific manner. | Little is known about whether presentation of endogenous and exogenous hepatitis B virus (HBV) surface antigens on APCs targeted by vaccination and/or virus-harboring hepatocytes influences de novo priming of CD8(+) T cells. We showed that surface antigen-expressing transfectants exclusively display a K(b) /S190 epitop... | [
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"Hepatitis B Surface Antigens",
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11040156 | Paraparesis, hypermanganesaemia, and polycythaemia: a novel presentation of cirrhosis. | Progressive myelopathy is a rare complication of chronic hepatic disease which has never been reported in the paediatric age group. We describe the 11 year course of an adolescent male with hepatic myelopathy caused by cryptogenic micronodular cirrhosis. His condition has been associated with persistent polycythaemia a... | [
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27198168 | Association of low back and knee pain with falls in Japanese community-dwelling older adults: A 3-year prospective cohort study. | AIM: To examine whether the chronicity and intensity of low back pain (LBP) or knee pain (KP) was associated with the occurrence of falls among a community-dwelling older population.METHODS: This was a community-based 3-year prospective cohort study. In 2009, baseline questionnaires were mailed to 3080 randomly selecte... | [
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11475021 | [Increased prevalence of overweight and obesity in Dutch children, and the detection of overweight and obesity using international criteria and new reference diagrams]. | OBJECTIVE: To determine the prevalence of overweight and obesity in Dutch children in 1980 and 1997 according to international criteria, and to design new reference diagrams for overweight and obesity in children.DESIGN: Descriptive.METHOD: The prevalence of overweight and obesity, based on height and weight data from ... | [
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84746 | Electroretinographic responses in Lafora disease. | In 3 patients with Lafora disease specific ERGs were observed resembling closely those seen in the Schubert-Bronschein type of night blindness. In contrast to essential hemeralopia, where the b-wave is completely lacking a gradual recovery of the b-wave was recorded in Lafora disease. The recovery occurred within about... | [
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617554 | Comparative neurohistological observations on the intrinsic innervation of pancreatic artery (blood vessel) in the representative of bird and mammal. | The present investigation was undertaken for the study of the comparative neurohistological observations of pancreatic-Artery (blood vessel) in Gallus domesticus (white leghorn) and Suncus murinus (Indian musk shrew) by cholinesterase technique. In Gallus, the innervation of arteries (blood vessel) was by a good number... | [
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17040961 | Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum. | BACKGROUND: Resistin is a newly identified adipocytokine which has demonstrated links between obesity and insulin resistance in rodents. In humans, proinflammatory properties of resistin are superior to its insulin resistance-inducing effects.OBJECTIVES: To assess resistin expression in synovial tissues, serum and syno... | [
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1818278 | [Neuromotor dyskinesia occurring during repeated injections of enkephalins into the rat striatum]. | The effect of 3-week daily injection of 5 or 15 mg enkephalin-like tetrapeptides (TP) into the rostral neostriatum was studied in chronic experiments on rats with implanted microcannulas. According to the type of TP, hyperkinesia or a pathological cataleptic status was registered in disorder of conditioned reflex behav... | [
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23073379 | [Hepatitis B prevention measures in chronic kidney disease patients]. | Hepatitis B virus infection is a major cause of morbidity and mortality among patients on dialysis, that are a target for vaccination. However, due to the poor immunogenicity of all types of vaccines in dialysis patients the collaboration between general practitioners, nephrologists and vaccination centers is essential... | [
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2980288 | Hydroxychloroquine in steroid dependent asthma. | A recent case report suggested that hydroxychloroquine had a steroid sparing effect in a patient with severe chronic asthma. We have studied the effect of hydroxychloroquine in a group of nine steroid dependent adult asthmatic patients using a randomised double blind crossover comparison of hydroxychloroquine and place... | [
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23070047 | Isolation of soluble and insoluble PrP oligomers in the normal human brain. | The central event in the pathogenesis of prion diseases involves a conversion of the host-encoded cellular prion protein PrP(C) into its pathogenic isoform PrP(Sc 1). PrP(C) is detergent-soluble and sensitive to proteinase K (PK)-digestion, whereas PrP(Sc) forms detergent-insoluble aggregates and is partially resistant... | [
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} |
23024276 | C/EBPâ is involved in the amplification of early granulocyte precursors during candidemia-induced "emergency" granulopoiesis. | Granulopoiesis is tightly regulated to meet host demands during both "steady-state" and "emergency" situations, such as infections. The transcription factor CCAAT/enhancer binding protein â (C/EBPâ) plays critical roles in emergency granulopoiesis, but the precise developmental stages in which C/EBPâ is required are un... | [
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24410681 | Comparing the removal of perchlorate when using single-walled carbon nanotubes (SWCNTs) or granular activated carbon: adsorption kinetics and thermodynamics. | This study aims to remove perchlorate using single-walled carbon nanotubes (SWCNTs) or granular activated carbon (GAC). Dynamic and equilibrium adsorption experiments were performed to evaluate the thermodynamic behavior of perchlorate on SWCNTs and GAC. Key parameters affecting the adsorption, such as pH, ionic streng... | [
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29438913 | Evaluation of caffeine effects on biochemical and genotoxic biomarkers in the neotropical freshwater teleost Prochilodus lineatus. | Caffeine is often found in aquatic environments, leading to concerns regarding its adverse consequences for aquatic biota. Biochemical and genotoxic biomarkers were analysed in juveniles of Prochilodus lineatus to evaluate the effects of caffeine. Fish were exposed to caffeine (0.3, 3 and 30 ìg L-1) for either 24 h or ... | [
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18975809 | [Fast detection of sugar content in fruit vinegar using NIR spectroscopy]. | For the fast and exact detection of sugar content of fruit vinegar, near infrared (NIR) spectroscopy technique combined with least squares support vector machines (LS-SVM) algorithm was used to build the prediction model of sugar content in the present research. NIR spectroscopy is a nondestructive, fast and accurate t... | [
4247,
87,
511,
2898,
2015,
1151,
5286,
131
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"Fruit",
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} |
23637024 | Highly ordered Pb(Zr₀.₅₂ Ti₀.₄₈)O₃ piezoelectric nanorod arrays. | One-dimensional (1D) piezoelectric nanostructures have attracted significant attention for a broad range of applications including optoelectronics, thermoelectrics, electrochemical and electromechanical converters. We demonstrate the synthesis of 1D nanostructures based upon Pb(Zr0.52Ti0.48)O3 (PZT) on conductive subst... | [
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4628,
3608,
2957,
9796,
573,
2388,
2389
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3285794 | Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats. | Previous studies demonstrated that a microsomal high-affinity N-nitrosodimethylamine demethylase activity and cytochrome P-450ac (an acetone/ethanol-inducible form) were induced by streptozotocin-induced diabetes in rats. In the present work, the induction was studied in detail in two chemically induced (by streptozoto... | [
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698,
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21695282 | Two evolutionary histories in the genome of rice: the roles of domestication genes. | Genealogical patterns in different genomic regions may be different due to the joint influence of gene flow and selection. The existence of two subspecies of cultivated rice provides a unique opportunity for analyzing these effects during domestication. We chose 66 accessions from the three rice taxa (about 22 each fro... | [
6086,
2476,
9956,
219,
6701,
5543
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"Evolution, Molecular",
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11198362 | Production of interleukin-12 is under the control of endogenous interleukin-10 in myocardial ischemia-reperfusion. | Interleukin (IL)-12 is a heterodimeric cytokine that is secreted mainly by antigen-presenting cells and plays a key role in determining the nature of immune response to exogenous or endogenous antigens. Negative regulators of IL-12 production include IL-10. With use of wild-type and IL-10-deficient mice, the aim of the... | [
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36,
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2872,
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"Myocardial Reperfusion Injury"
] | {
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} |
7218056 | Cost of hypertension control at the workplace. | A cost analysis of hypertension treatment at the workplace indicates that average patient cost in 1978 was $194.77. The distribution of cost is: clinical personnel, 26.7%; administrative personnel, 26.7%; drugs, 23.9%; laboratory, 3.4%; clinical supplies, 1.1%; general supplies and other operating expenses, 8.7%; equip... | [
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3,
1312,
16775
] | [
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] | {
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17419256 | Quantitative analysis of Doppler waveform of hepatic veins for assessment of hepatic functional reserve. | BACKGROUND/AIMS: The Doppler waveform of hepatic veins in healthy humans is a triphasic waveform (two negative waves and one positive). Recent studies emphasize the role of Doppler ultrasonography in the evaluation of liver cirrhosis. The analysis of the Doppler waveform of hepatic veins might be a useful and non-invas... | [
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6403478 | Where is the popular mandate? A reply to conventional wisdom. | Current federal policies include substantial cuts in government expenditures for health programs and for care of the poor, elderly, and handicapped, and the weakening of government regulations in health and medical care. These policies are presented by many political, academic, and medical leaders as responding to a po... | [
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22073313 | RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense. | RpkA (Receptor phosphatidylinositol kinase A) is an unusual seven-helix transmembrane protein of Dictyostelium discoideum with a G protein coupled receptor (GPCR) signature and a C-terminal lipid kinase domain (GPCR-PIPK) predicted as a phosphatidylinositol-4-phosphate 5-kinase. RpkA-homologs are present in all so far ... | [
6026,
1591,
3162
] | [
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"Phagocytosis",
"Receptors, G-Protein-Coupled"
] | {
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10331667 | CD36 mediates long-chain fatty acid transport in human myocardium: complete myocardial accumulation defect of radiolabeled long-chain fatty acid analog in subjects with CD36 deficiency. | Long-chain fatty acids (LCFA) are the major energy substrate for heart and their oxidation is important for achieving maximal cardiac work. However, the mechanism of uptake of LCFA by myocardium has not been clarified. We previously reported that bovine myocardial LCFA transporter has a sequence homology to human CD36.... | [
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666,
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"Fatty Acids",
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"Heart",
"Humans",
"Male",
"Middle Aged",
"Mutation",
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2567873 | Randomised, controlled trial of squatting in the second stage of labour. | A new obstetric aid, the 'Birth Cushion' allows the parturient to sink into a supported squatting posture for the second stage of labour and delivery; it fits onto conventional delivery beds. A prospective, controlled trial of 427 primiparae compared the outcome of labour in women randomly allocated to squatting (218) ... | [
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3426582 | Lamin A is not synthesized as a larger precursor polypeptide. | Isolation of rat liver nuclei in the presence of N-ethylmaleimide (NEM) led to the recovery in the final nuclear matrix of a higher molecular weight form of lamin A. The 2 kDa larger form was identified as lamin A by isoelectric point determination, recognition by an anti-lamin A and C monoclonal antibody and peptide m... | [
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15602362 | [Primary treatment of Parkinson's disease: the application of the March 2000 consensus rules in the Nord Pas-de-Calais area]. | INTRODUCTION: For Parkinson's disease, the choice of the initial treatment is essentially between L-Dopa and dopaminergic agonists. Selegilin, anticholinergic and amantadine can be used for subjects with moderate symptoms. The first French consensus conference, held in 2000, elaborated decision-making rules which take ... | [
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23222492 | Iatrogenic Exserohilum infection of the central nervous system: mycological identification and histopathological findings. | An outbreak of fungal infections has been identified in patients who received epidural injections of methylprednisolone acetate that was contaminated with environmental molds. In this report, we present the mycological and histopathological findings in an index case of Exserohilum meningitis and vasculitis in an immuno... | [
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19329142 | The Cu, Mn and Zn concentration of sheep wool: influence of washing procedures, age and colour of matrix. | No standard or wholly proven method to determine the trace metal status of human or animal 'hair' yet exists. It is well known that hair-metal concentrations are highly influenced by washing procedures applied before analysis. A novel method to determine the efficiency of washing procedures at removing exogenous contam... | [
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31317032 | Potential Protective Effect of Achillea fragrantissima | Adriamycin (Adr) is a cytotoxic anthracycline agent that is utilized to manage many types of tumors, but its clinical use is undesirable due to severe cardiotoxicity. The present study aimed to investigate the cardioprotective effect of Achillea fragrantissima (A. fragrantissima) against Adr-induced cardiotoxicity thro... | [
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25095442 | [Study on SPAD visualization of pumpkin leaves based on hyperspectral imaging technology]. | Visible/near-infrared (380 approximately 1 030 nm) hyperspectral imaging technique was used to realize SPAD visualization of pumpkin leaves in the present study. Downy mildew could be diagnosed rapidly according to significant positive correlation between downy mildew epidemic and chlorophyll content. Leaves uninfected... | [
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8955,
834,
3669,
2730,
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"Least-Squares Analysis",
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"Plant Diseases",
"Plant Leaves",
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4019997 | Prevalence and significance of cardiovascular disease and hypertension in elderly patients with dementia and depression. | The prevalence and significance of clinical heart disease and hypertension were compared in three groups of elderly patients. One group was diagnosed as dementia of an Alzheimer's type (AD), another as multiinfarct dementia (MID), and the third as major depression. Clinical heart disease and hypertension were uncommon ... | [
133,
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1312,
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6424
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15650785 | [Immunoreactivity studies on synthetic peptides deriving from immunodominant region of hepatitis C virus NS5a gene]. | OBJECTIVE: To identify the location of major immunodominant antigenic region and study the relationship between the gene heterogeneity and immunoreactivity via detecting antigenic reactivity of synthetic peptides deriving from immunodominant region in different genotypes of hepatitis C virus (HCV) NS5a gene.METHODS: In... | [
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2256212 | [Drugs, narcotics--knowledge and habits in schools]. | During the school session 1988/1989, the school doctors in the County of Roskilde carried out a questionnaire investigation among 4,004 pupils in the seventh and ninth classes about their knowledge, habits and attitudes to euphorising drugs. The questionnaire investigation was voluntary and anonymous and this probably ... | [
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22016525 | á7-Containing and non-á7-containing nicotinic receptors respond differently to spillover of acetylcholine. | We explored whether nicotinic acetylcholine receptors (nAChRs) might participate in paracrine transmission by asking if they respond to spillover of ACh at a model synapse in the chick ciliary ganglion, where ACh activates diffusely distributed á7- and á3-containing nAChRs (á7-nAChRs and á3*-nAChRs). Elevating quantal ... | [
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10686795 | [Clinical case of the month. Mental confusion due to the administration of tramadol in a patient treated with MOAI]. | However currently less used, MAOI (monoamine-oxidase inhibitor) antidepressants have specific indications like refractory or atypical depressions. The main difficulties related to MAOI therapy consist in their potentially very dangerous interactions with certain foods on the one side, many medications on the other side... | [
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"Phenelzine",
"Tramadol"
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16404795 | High-performance liquid chromatography-mass spectrometry in the clinical laboratory. | The development of HPLC-atmospheric pressure ionization-mass spectrometry (HPLC-MS) has presented clinical laboratories with a powerful analytic tool. The aim of this paper is to provide an overview of the current status of HPLC-MS in the clinical laboratory; to discuss the challenges to mass spectrometry in this setti... | [
626,
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1930
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"Clinical Laboratory Techniques",
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6325345 | Receptor blockade as a mechanism of deactivation of human neutrophils by pepstatin and formyl-Met-Leu-Phe. | The pentapeptide pepstatin was shown to be chemotactic for human neutrophils by two techniques: ED50 for chemotaxis was found to be 3 microM by the agarose method and 0.2 microM by the Boyden chamber technique. Pepstatin also induced superoxide radical generation, release of lysosomal enzymes, and a transient increase ... | [
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18398420 | Effects of the 'live high-train low' method on prooxidant/antioxidant balance on elite athletes. | BACKGROUND/OBJECTIVES: We previously demonstrated that acute exposure to hypoxia (3 h at 3000 m) increased oxidative stress markers. Thus, by using the 'living high-training low' (LHTL) method, we further hypothesized that intermittent hypoxia associated with endurance training alters the prooxidant/antioxidant balance... | [
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22874087 | Convergent validity of the international physical activity questionnaire (IPAQ): meta-analysis. | OBJECTIVE: The purpose of the present study was to use a meta-analytic approach to examine the convergent validity of the international physical activity questionnaire (IPAQ).DESIGN: Systematic review by meta-analysis.SETTING: The relevant studies were surveyed from five electronic databases. Primary outcomes of intere... | [
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25213795 | KITLG is a novel target of miR-34c that is associated with the inhibition of growth and invasion in colorectal cancer cells. | MiR-34c is considered a potent tumour suppressor because of its negative regulation of multiple target mRNAs that are critically associated with tumorigenesis and metastasis. In the present study, we demonstrated a novel target of miR-34c, KITLG, which has been implicated in colorectal cancer (CRC). First, we found a s... | [
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25113250 | Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway. | Cervical cancer (CC) is a malignant neoplasm arising from cells originating in the cervix uteri, among the top causes of death from cancer in women. In a gene expression profiling study of metabolic response to treatment, PI3K/Akt signaling pathway are associated with the development of CC. A common mechanism of Akt ac... | [
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1741630 | Exercise as a health-promoting lifestyle choice. | The primary purpose of this exploratory study was to examine differences between exercisers and nonexercisers in self-esteem, perceived benefits of exercise, and perceived barriers to exercise. Second, we investigated how much variation in group membership as an exerciser or nonexerciser could be explained by the relat... | [
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18756269 | Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs. | The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and survival. The Sec6/8 complex, or exocyst, has emerged as a principal direct effector complex for Ral GTPase... | [
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20306,
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6847868 | Thyroid-stimulating hormone and thyroglobulin levels decrease with chronological age in children and adolescents. | TSH, thyroglobulin (Tg), and the free T4 index were determined and related to chronological age in 24 normal boys (aged 7.6-17.6 yr; mean, 12.6 +/- 1.5 yr) and 20 normal girls (aged 7.8-17.0 yr; mean, 12.2 +/- 1.4 yr). There was no significant (P greater than 0.1) difference in mean serum TSH (3.06 +/- 2.07 vs. 2.97 +/... | [
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3,
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9291,
2329,
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30032584 | [Preliminary research on Zhang Song's Jiu yuan fang | Written by Zhang Song, a physician in the Southern Song Dynasty, Jiu yuan fang (Formulary of Exploring Cause) was a lost clinical experienced formulary book. Totally 124 items of its original texts were quoted and remained in some other ancient Chinese medical books, such as Fu zai wan an fang (Formulary for Absolute S... | [
12536,
6960,
3,
3356,
3591
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"Books",
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"Humans",
"Medicine, Chinese Traditional",
"Physicians"
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29587832 | Community analysis of the abundance and diversity of biting midge species (Diptera: Ceratopogonidae) in three European countries at different latitudes. | BACKGROUND: The outbreaks of bluetongue and Schmallenberg disease in Europe have increased efforts to understand the ecology of Culicoides biting midges and their role in pathogen transmission. However, most studies have focused on a specific habitat, region, or country. To facilitate wider comparisons, and to obtain a... | [
30,
4017,
13396,
1719,
9310,
2,
3216,
1454,
4879,
946,
348
] | [
"Animals",
"Biodiversity",
"Ceratopogonidae",
"Ecosystem",
"Entomology",
"Female",
"Insect Vectors",
"Italy",
"Microscopy",
"Netherlands",
"Sweden"
] | {
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} |
26277521 | [Bilateral ultrasound-guided supraclavicular brachial plexus block in shoulder joint release surgery for shoulder periarthritis]. | OBJECTIVE: To observe the anesthetic efficacy and safety of bilateral ultrasound-guided supraclavicular brachial plexus block in patients undergoing arthrolysis for shoulder periarthritis.METHODS: Twenty-seven patients (ASA class I-II) undergoing bilateral shoulder joint release surgery and 24 ml received bilateral ult... | [
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242,
2355,
42,
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] | [
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"Brachial Plexus Block",
"Diaphragm",
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"Lidocaine",
"Orthopedic Procedures",
"Pain Measurement",
"Periarthritis",
"Ropivacaine",
"Shoulder Joint",
"Ultrasonography"
] | {
"A": 1,
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9246053 | Effect of endoscopic sphincterotomy on gallbladder motility. | In experimental animals, sphincterotomy facilitates passage of solids from the gallbladder and inhibits gallstone formation apparently by improvement in gallbladder emptying. In humans, however, gallbladder emptying has not been studied following endoscopic sphincterotomy (ES) in patients with gallstones. We therefore ... | [
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16697,
8072,
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"Case-Control Studies",
"Ceruletide",
"Cholelithiasis",
"Female",
"Gallbladder",
"Gallbladder Emptying",
"Gallstones",
"Gastrointestinal Agents",
"Humans",
"Male",
"Middle Aged",
"Prospective Studies",
"Sphincterotomy, Endoscopic",
"Ultrasonography"
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29787682 | Maternal Perception of Adequacy of Mother's Milk Among Mothers Giving Birth at a Teaching Hospital in Sri Lanka. | BACKGROUND:: Sri Lanka boasts high rates of early and exclusive breastfeeding. Perceived inadequacy of milk, a global problem, is the main cause for early cessation of breastfeeding.RESEARCH AIMS:: The aims of this study are to (a) determine the prevalence, (b) identify the risk factors, and (c) ascertain the associati... | [
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"Adult",
"Breast Feeding",
"Cross-Sectional Studies",
"Female",
"Hospitals, Teaching",
"Humans",
"Lactation",
"Milk, Human",
"Mothers",
"Perception",
"Pregnancy",
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"Sri Lanka",
"Surveys and Questionnaires",
"Young Adult"
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9737451 | Continued expansion of aortic necks after endovascular repair of abdominal aortic aneurysms. EVT Investigators. EndoVascular Technologies, Inc. | BACKGROUND: Longitudinal studies have revealed that the aortic segment proximal to an infrarenal abdominal aortic aneurysm (AAA) is at risk for continued enlargement after a standard aneurysm repair. Similarly, preliminary reports have shown expansion of one or both aortic necks after endovascular repair. Although some... | [
133,
5624,
1569,
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7677,
3,
35,
160,
695,
2608,
1099
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"Aged",
"Aorta, Abdominal",
"Aortic Aneurysm, Abdominal",
"Blood Vessel Prosthesis Implantation",
"Dilatation, Pathologic",
"Humans",
"Male",
"Middle Aged",
"Postoperative Complications",
"Reoperation",
"Tomography, X-Ray Computed"
] | {
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15561971 | Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. | The role of monocytes/macrophages in the pathogenesis of ischemia-reperfusion injury (IRI) is unknown. We sought to determine whether activation of macrophage adenosine 2A (A(2A)) receptors (A(2A)Rs) mediates tissue protection. We subjected C57Bl/6 mice infused with clodronate [dichloromethylene bisphosphonate (Cl(2)MB... | [
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"Animals",
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"Cell Line",
"Clodronic Acid",
"Cyclohexanecarboxylic Acids",
"Cytokines",
"Humans",
"Kidney",
"Liposomes",
"Macrophages",
"Mice",
"Mice, Inbred C57BL",
"Purines",
"RNA, Messenger",
"Receptor, Aden... | {
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25515279 | Shorter Mandibular Length is Associated with a Greater Fall in AHI with Weight Loss. | RATIONALE: Obesity is a major risk factor towards the development of obstructive sleep apnea, while significant weight loss (both conservatively managed and surgically assisted) has a variable effect upon its severity. Differences in the effect of weight loss on obstructive sleep apnea may be due to underlying craniofa... | [
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"Male",
"Mandible",
"Middle Aged",
"Obesity",
"Severity of Illness Index",
"Sleep Apnea, Obstructive",
"Weight Loss"
] | {
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22943633 | Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. | AIM: The present study evaluated the possibility of drug interactions involving blueberry juice (BBJ) and substrate drugs whose clearance is dependent on cytochromes P4503A (CYP3A) and P4502C9 (CYP2C9).METHODS: A 50:50 mixture of lowbush and highbush BBJ was evaluated in vitro as an inhibitor of CYP3A activity (hydroxy... | [
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"Aryl Hydrocarbon Hydroxylases",
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"Blueberry Plants",
"Buspirone",
"Citrus paradisi",
"Cytochrome P-450 CYP2C9",
"Cytochrome P-450 CYP3A",
"Cytochrome P-450 CYP3A Inhibitors",
"Drug Interactions",
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"Fluconazole",
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1109736 | Anemia in adolescence. 2. Hemoglobinopathies and other causes. | Many complex forces are at work during adolescence which can contribute to the occurrence of anemia. Careful consideration of the entire patient should enable a physician to identify the unusual as well as the more common causes of anemia in this age group. Anemia in teenage girls is primarily due to menstrual iron los... | [
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"Anemia, Hypochromic",
"Blood Transfusion",
"Contraceptives, Oral",
"Diet",
"Folic Acid Deficiency",
"Glucosephosphate Dehydrogenase Deficiency",
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"Infectious Mononucleosis",
"Iron",
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9474825 | Predictors of the provision of intrapartum care by general practitioners: five-year cohort study. | BACKGROUND: There is little published evidence that any aspect of vocational training for general practice improves the quality of care provided by general practitioners (GPs).AIM: To investigate whether aspects of education and vocational training predict whether GPs provide intrapartum care.METHOD: A five-year prospe... | [
1812,
3281,
5425,
477,
2,
912,
3,
8980,
20,
1406
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"Obstetrics",
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] | {
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16218683 | Identification of metallic-smelling 1-octen-3-one and 1-nonen-3-one from solutions of ferrous sulfate. | Taste threshold tests of ferrous sulfate (FeSO4) solutions have been confounded by the presence of putative odorants. To detect the presence of odorants released from these solutions solid-phase microextraction (SPME) was used to collect volatiles in the headspace above FeSO4 solutions. Gas chromatography-olfactometry ... | [
1398,
9822,
3,
4602,
4174,
4696,
720
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} |
9886297 | The crystal structure of a complex of p11 with the annexin II N-terminal peptide. | The aggregation and membrane fusion properties of annexin II are modulated by the association with a regulatory light chain called p11.p11 is a member of the S100 EF-hand protein family, which is unique in having lost its calcium-binding properties. We report the first structure of a complex between p11 and its cognate... | [
30,
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551,
1277,
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37,
372,
957,
8325
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"Annexin A2",
"Binding Sites",
"Calcium",
"Crystallography, X-Ray",
"Humans",
"Molecular Sequence Data",
"Protein Binding",
"Protein Conformation",
"S100 Proteins"
] | {
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} |
31568867 | Operator Experience and Outcomes of Transcatheter Mitral Valve Repair in the United States. | BACKGROUND: Transcatheter mitral valve repair (TMVr) for the treatment of mitral regurgitation (MR) is a complex procedure that requires development of a unique skillset.OBJECTIVES: The purpose of this study was to examine the relationship between operator experience and procedural results of TMVr.METHODS: TMVr device ... | [
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3,
5426,
35,
3447,
5356,
2433,
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132
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"Aged, 80 and over",
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"Endovascular Procedures",
"Female",
"Humans",
"Learning Curve",
"Male",
"Mitral Valve",
"Mitral Valve Insufficiency",
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6106063 | Synthesis of 8-aryltetrahydroisoquinolines as dopamine antagonists and evaluation for potential neuroleptic activity. | The synthesis of 8-(methoxyphenyl)-1,2,3,4-tetrahydroisoquinolines using aryloxazolines as key intermediates is described. Nucleophilic displacement on an o-methoxyphenyloxazoline by an aryl Grignard reagent, followed by electrophilic substitution at the other ortho position, provided a specific route to the properly s... | [
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15963676 | Development of a rapid and sensitive LC-ESI/MS/MS assay for the quantification of propofol using a simple off-line dansyl chloride derivatization reaction to enhance signal intensity. | A rapid, selective and sensitive method was developed for the determination of propofol concentration using an off-line dansyl chloride derivatization step to enhance signal intensity. The method consisted of a protein precipitation extraction followed by derivatization with dansyl chloride and analysis by liquid chrom... | [
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2702349 | Delayed cerebrospinal-fluid shunt infection in children. | Twelve patients with shunt infection occurring more than 6 months following shunt implantation or revision were identified and their charts reviewed. These cases were accumulated over a 9-year period, and delays from shunt surgery to detection were as long as 11 years. For 5 patients, no antecedent infection or surgery... | [
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486452 | Glycodeoxycholate transport in brush border membrane vesicles isolated from rat jejunum and ileum. | The transport of the bile salt, glycodeoxycholate, was studied in vesicles derived from rat jejunal and ileal brush border membranes using a rapid filtration technique. The uptake was osmotically sensitive, linearly related to membrane protein and resembled D-glucose transport. In ileal, but not jejunal, vesicles glyco... | [
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3895941 | Diagnosis of congenital syphilis by immunofluorescence following fetal death in utero. | The etiology of fetal death may be difficult to identify, particularly with the presence of marked fetal maceration and autolysis. Immunofluorescence with human antitreponemal antibody was used in this case to establish a diagnosis of congenital syphilis. | [
9,
2,
10980,
2065,
3,
427,
20,
20249
] | [
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"Fetal Death",
"Fluorescent Antibody Technique",
"Humans",
"Liver",
"Pregnancy",
"Syphilis, Congenital"
] | {
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} |
1764014 | Techniques to enhance safety in acceleration research and fighter aircrew training. | Acceleration (+Gz) research and aircrew training using human centrifuges involves considerable stress that can alter normal cardiovascular and neurologic function even in completely healthy individuals. It is clear that electrocardiographic rate, rhythm, and conduction disturbances are frequently associated with +Gz ex... | [
7873,
4619,
2860,
4363,
731,
4630,
13813,
3,
4646,
177,
13814
] | [
"Aerospace Medicine",
"Arrhythmias, Cardiac",
"Cardiovascular Diseases",
"Central Nervous System Diseases",
"Electrocardiography",
"Gravitation",
"Gravity Suits",
"Humans",
"Military Personnel",
"Risk Factors",
"Unconsciousness"
] | {
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} |
26071424 | Treatment of feline giardiasis during an outbreak of diarrhoea in a cattery: potential effects on faecal Escherichia coli resistance patterns. | OBJECTIVES: An outbreak of diarrhoea involving 16 cats at a cattery in Norway was investigated. Treatment and control of the outbreak were the primary objectives, but the effects of treatment on the antimicrobial resistance profiles of Escherichia coli isolated from faeces were also investigated.METHODS: Faecal samples... | [
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2833365 | Cell phenotype instability in preneoplastic foci of rat liver. | Carcinogenesis is a multi-step process in which genetic--phenotypic instability and sequential selection of preneoplastic cells for increased growth capacity and other neoplastic characteristics are essential phenomena. During chemical carcinogenesis in rat liver, the development of enzyme-deficient foci, their clonal ... | [
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655,
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19527563 | Random-effects meta-analysis of correlations: Monte Carlo evaluation of mean estimators. | Several authors have cautioned against using Fisher's z-transformation in random-effects meta-analysis of correlations, which seems to perform poorly in some situations, especially with substantial inter-study heterogeneity. Attributing this performance largely to the direct z-to-r transformation (DZRT) of Fisher z res... | [
87,
1541,
7003,
8475,
2614,
3863
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} |
31511589 | New crosstalk between probiotics Lactobacillus plantarum and Bacillus subtilis. | It was reported that oral administration of Bacillus favored the growth of Lactobacillus in the intestinal tract. Here, this phenomenon was confirmed by co-cultivation of Bacillus subtilis 168 and Lactobacillus plantarum SDMCC050204-pL157 in vitro. To explain the possible molecular mechanisms, B. subtilis 168 cells wer... | [
6629,
4781,
3502,
855,
3765,
13556,
4564,
1664,
364
] | [
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"Heme",
"Hydrogen Peroxide",
"Intestines",
"Lactobacillus plantarum",
"Microbial Interactions",
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"Reactive Oxygen Species"
] | {
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} |
18492490 | Small dense low-density lipoprotein cholesterol concentration and carotid atherosclerosis. | Low-density lipoprotein cholesterol (LDL-C) and the small dense LDL (SdLDL) phenotype are both predictors for ischemic heart disease. We examined whether cholesterol of SdLDL (SdLDL-C) is more closely associated with carotid artery intima-media thickness (CA-IMT), a surrogate measure of atherosclerosis, than LDL-C and ... | [
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61,
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4545,
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1100
] | [
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"Lipoproteins, LDL",
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] | {
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8308607 | Heterotopic ossification after femoral intramedullary rodding. | Heterotopic ossification (HO) after femoral intramedullary rodding is a significant complication of the procedure. One hundred eighteen cases of femoral roddings performed on 113 patients were available for review. The data were computerized and evaluated using univariate analysis and multivariate regression analysis. ... | [
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6203090 | Psychiatric aspects of learning difficulties. | This article describes the process of clinical assessment that may lead to differential treatment of psychiatric-related learning difficulties. The authors review differences in information processing among individuals with attention, affective, and primary thought disorders. | [
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23735742 | Design, synthesis and antibacterial evaluation of novel AHL analogues. | Two series of novel AHL analogues were designed, synthesized and evaluated for antibacterial activity under cell membrane conditions in vitro. Analogues 4a-c and 4g-m presented potent activity against Gram-positive bacteria. Especially the analogue 4l exerted the most potent inhibition against Bacillus subtilis with MI... | [
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192,
10528,
1460,
5180,
5181,
1172,
8534
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"4-Butyrolactone",
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2640040 | [Local anesthetics (LA). Adverse reactions from the use of LA (IV)]. | Most common and significant adverse reactions directly attributable to the administration of local anesthetics which occur in dental practice are discussed. Both most severe systemic reactions--uncommonly found--and local reactions--of lesser importance--are reviewed. Tolerance, subtoxic doses and general toxicity of t... | [
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134,
10753,
3,
996
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"Anesthetics, Local",
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17873166 | Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes: ACCP evidenced-based clinical practice guidelines (2nd edition). | BACKGROUND: This chapter of the guidelines is intended to provide an evidence-based assessment of the initial evaluation of patients recognized as having lung cancer and the recognition of paraneoplastic syndromes.METHODS: The current medical literature that is applicable to this issue was identified by a computerized ... | [
12039,
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3140,
12040
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2132699 | Regulation of biotechnology in the United States and Canada. | The regulation of biotechnology in the United States and Canada is based on principles that reflect respect for the new technology, yet also recognize that most traditional approaches to regulation, employing sound science and common sense, still apply. Four specific principles form the framework on which regulatory sc... | [
30,
6016,
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4195,
132,
15865,
3325
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"Biotechnology",
"Canada",
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