pmid stringlengths 2 8 | title stringlengths 0 326 | abstract stringlengths 57 5.86k | label_ids listlengths 1 46 | label_names listlengths 1 46 | mesh_roots dict |
|---|---|---|---|---|---|
17054753 | Prevalence of multiresistant Gram-negative organisms in a surgical hospital in Ho Chi Minh City, Vietnam. | OBJECTIVE: To determine resistance patterns of multiresistant Gram-negative organisms at a surgical hospital in Ho Chi Minh City, Vietnam, in order to guide appropriate antibiotic prescribing and improve infection control procedures.METHOD: All samples sent in for microbiological analysis over a 3-month period were inc... | [
192,
17720,
2831,
2886,
1130,
6704,
11205,
2,
5490,
5180,
4563,
3,
35,
160,
86,
1175
] | [
"Anti-Bacterial Agents",
"Cephalosporin Resistance",
"Ciprofloxacin",
"Cross Infection",
"Drug Resistance, Multiple, Bacterial",
"Enterobacteriaceae",
"Enterobacteriaceae Infections",
"Female",
"Gentamicins",
"Gram-Negative Bacteria",
"Gram-Negative Bacterial Infections",
"Humans",
"Male",
... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 1
} |
27470074 | Evidence of iteroparity in the widely distributed diadromous fish inanga Galaxias maculatus and potential implications for reproductive output. | Gaps in understanding variability among populations of inanga Galaxias maculatus in the timing of reproduction were addressed in southern New Zealand (NZ), where G. maculatus constitutes a declining fishery. Reproductive activity was delayed by 1 month on the west coast compared with the east coast and the west coast s... | [
30,
1719,
670,
4010,
18108,
4034,
23
] | [
"Animals",
"Ecosystem",
"Fertility",
"New Zealand",
"Osmeriformes",
"Reproduction",
"Seasons"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 1
} |
7932773 | Regional and age variations in growing tendon. | Gastrocnemius tendons of 10 White Leghorn chickens at 6, 8, and 12 weeks of age were divided into proximal, middle, and distal portions to assess regional variability in composition and growth. Body weight increases approximately 150% during the period examined, whereas the lateral gastrocnemius muscle and tendon incre... | [
437,
17065,
30,
862,
5511,
2904,
3689,
1226,
9340,
35,
3391,
6817
] | [
"Aging",
"Amino Sugars",
"Animals",
"Body Weight",
"Cell Count",
"Chickens",
"Collagen",
"DNA",
"Hydroxyproline",
"Male",
"Spectrophotometry",
"Tendons"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8345461 | Culture of rabbit zygotes into blastocysts in protein-free medium with one to twenty per cent oxygen. | Embryos were collected from superovulated Dutch rabbits 19 h after injection of LH and insemination. The embryos were at the one-cell stage at that time and those judged to be normal by the absence of granular cytoplasm and regular shape were distributed randomly within donors into culture dishes containing 500 microli... | [
30,
2186,
51,
3067,
6110,
2,
1180,
772,
4200
] | [
"Animals",
"Blastocyst",
"Cells, Cultured",
"Culture Media",
"Embryonic and Fetal Development",
"Female",
"Oxygen",
"Rabbits",
"Zygote"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
18184329 | Adeno-associated viral vector transduction of green fluorescent protein in kidney: effect of unilateral ureteric obstruction. | OBJECTIVE: To evaluate adeno-associated virus (AAV) mediated renal gene transfer, by examining the localization and time course of gene expression in the kidneys of mice with unilateral ureteric obstruction (UUO) and controls. AAV is a replication-defective virus that has the potential to deliver genes into the kidney ... | [
30,
10835,
1465,
2,
441,
2419,
2420,
663,
3400,
36,
5948
] | [
"Animals",
"Dependovirus",
"Feasibility Studies",
"Female",
"Gene Expression",
"Genetic Therapy",
"Genetic Vectors",
"Green Fluorescent Proteins",
"Kidney Diseases",
"Mice",
"Ureteral Obstruction"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
9146665 | Vascular endothelial growth factor (VEGF) expression in human prostate cancer: in situ and in vitro expression of VEGF by human prostate cancer cells. | PURPOSE: A growing body of literature supports the role of angiogenesis in the development and spread of a variety of human cancers including prostate cancer (Pca). Angiogenesis is controlled by chemical signals known as angiogenic factors (AF) however, little is known about angiogenesis factors in prostate cancer. We ... | [
51,
5415,
3,
4,
5038,
35,
1832,
2566,
5420
] | [
"Cells, Cultured",
"Endothelial Growth Factors",
"Humans",
"Immunohistochemistry",
"Lymphokines",
"Male",
"Prostatic Neoplasms",
"Vascular Endothelial Growth Factor A",
"Vascular Endothelial Growth Factors"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8397061 | Brain metastasis as the site of relapse in germ cell tumor of testis. | BACKGROUND: Brain metastases occur in approximately 8-15% of patients with testicular germ cell tumors and invariably are associated with relapse at other sites, most commonly the lungs, or as a terminal event.METHODS: The authors, from the Institute Rotary Cancer Hospital, a regional cancer center in northern India, d... | [
9,
133,
2406,
18760,
3,
35,
924,
1237,
708
] | [
"Adult",
"Aged",
"Brain Neoplasms",
"Dysgerminoma",
"Humans",
"Male",
"Neoplasms, Germ Cell and Embryonal",
"Recurrence",
"Testicular Neoplasms"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
25733527 | Retinal angiography with real-time speckle variance optical coherence tomography. | This report describes a novel, non-invasive and label-free optical imaging technique, speckle variance optical coherence tomography (svOCT), for visualising blood flow within human retinal capillary networks. This imaging system uses a custom-built swept source OCT system operating at a line rate of 100 kHz. Real-time ... | [
2658,
3690,
5378,
3,
1016,
97,
17174,
5307,
3695,
131,
6447
] | [
"Diabetic Retinopathy",
"Fluorescein Angiography",
"Fundus Oculi",
"Humans",
"Regional Blood Flow",
"Reproducibility of Results",
"Retinal Artery Occlusion",
"Retinal Vein Occlusion",
"Retinal Vessels",
"Time Factors",
"Tomography, Optical Coherence"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
9033892 | [Strabismus in Cameroon]. | PURPOSE: We undertook a study on strabismus in order to determine the characteristics of this disease in Cameroon.MATERIAL AND METHODS: A prospective study was carried out in the ophthalmological unit of the Douala General Hospital from November 1991 to October 1995. All patients were examined and followed regularly by... | [
204,
12109,
7741,
104,
105,
11193,
17149,
2,
3,
14,
35,
10973,
111,
7238
] | [
"Adolescent",
"Amblyopia",
"Cameroon",
"Child",
"Child, Preschool",
"Esotropia",
"Exotropia",
"Female",
"Humans",
"Infant",
"Male",
"Nystagmus, Pathologic",
"Prospective Studies",
"Strabismus"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
28526568 | Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100°. | OBJECTIVE: The aim of this study was to evaluate the complications, efficacy and safety of posterior vertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100°.METHODS: The medical records of 17 patients (mean age 17.9 (range, 9-27) years) with SAK who underwent PVCR, were reviewed. Mean follo... | [
204,
9,
104,
2,
3,
414,
5839,
2351,
35,
2355,
695,
189,
598,
141,
144,
3184,
27
] | [
"Adolescent",
"Adult",
"Child",
"Female",
"Humans",
"Incidence",
"Kyphosis",
"Lumbar Vertebrae",
"Male",
"Orthopedic Procedures",
"Postoperative Complications",
"Radiography",
"Retrospective Studies",
"Severity of Illness Index",
"Treatment Outcome",
"Turkey",
"Young Adult"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
8461112 | Age differences in hostility among middle-aged and older adults. | Multiple measures of hostility were administered to middle-aged and older volunteers. There was a positive association between age and self-report measures reflecting hostile beliefs about others, including cynicism and suspiciousness. There was a weak inverse relationship between age and self-report measures of the ov... | [
9,
133,
437,
7048,
2,
3857,
9853,
3,
496,
9854,
35,
160,
1699
] | [
"Adult",
"Aged",
"Aging",
"Anger",
"Female",
"Gender Identity",
"Hostility",
"Humans",
"Interpersonal Relations",
"Irritable Mood",
"Male",
"Middle Aged",
"Personality Assessment"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 0,
"F": 1,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
10547368 | The majority of clathrin coated vesicles from lactating rabbit mammary gland arises from the secretory pathway. | Clathrin coated vesicles were isolated from lactating rabbit mammary gland by differential centrifugation, centrifugation on (2)H2O-sucrose cushions and Sephacryl S-1000 chromatography. Mammary epithelial cells contain an unexpectedly high quantity of clathrin coated vesicles which appear heterogeneous in size, with a ... | [
21114,
9885,
30,
1261,
206,
424,
10696,
21115,
1615,
4643,
777,
1498,
2,
4,
2484,
16,
2736,
285,
3988,
772,
10586,
4757
] | [
"Adaptor Protein Complex alpha Subunits",
"Adaptor Proteins, Vesicular Transport",
"Animals",
"Biological Transport",
"Brain",
"Cattle",
"Clathrin",
"Coated Vesicles",
"Cytoplasmic Granules",
"Electrophoresis, Agar Gel",
"Electrophoresis, Polyacrylamide Gel",
"Epithelial Cells",
"Female",
... | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
26154928 | Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury. | In patients with severe acute kidney injury (AKI) but no urgent indication for renal replacement therapy (RRT), the optimal time to initiate RRT remains controversial. While starting RRT preemptively may have benefits, this may expose patients to unnecessary RRT. To study this, we conducted a 12-center open-label pilot... | [
1407,
133,
3143,
4761,
1465,
2,
3446,
3,
989,
594,
35,
160,
2580,
15831,
177,
141,
131,
7808,
144,
17427
] | [
"Acute Kidney Injury",
"Aged",
"Canada",
"Critical Illness",
"Feasibility Studies",
"Female",
"Hospital Mortality",
"Humans",
"Kidney",
"Length of Stay",
"Male",
"Middle Aged",
"Pilot Projects",
"Renal Replacement Therapy",
"Risk Factors",
"Severity of Illness Index",
"Time Factors",... | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
11341368 | The evaluation of novel mixed metal hydroxy-carbonates as phosphate binders: an in-vivo study in the rat. | A number of novel phosphate binders based on mixed metal hydroxide structures incorporating Fe and Ca, or Fe and Mg (classified as CT, Crosfield test compounds), were compared with the established phosphate binders Mg(OH)2, Al(OH)3, CaCO3 and a commercial hydrotalcite (Al- and Mg-based) using a rat model. The changes i... | [
30,
15740,
13668,
2654,
919,
473,
43,
69
] | [
"Animals",
"Carbonates",
"Hydroxides",
"Iron",
"Metals",
"Phosphates",
"Rats",
"Rats, Sprague-Dawley"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
25010770 | Tocilizumab, a proposed therapy for the cachexia of Interleukin6-expressing lung cancer. | BACKGROUND: We previously reported the role of IL-6 in a murine model of cancer cachexia and currently documented a patient in whom tocilizumab, anti-IL-6 receptor antibody, dramatically improved cachexia induced by IL-6 over-expressing lung cancer. Despite this potential to alleviate cancer cachexia, tocilizumab has n... | [
133,
310,
30,
3321,
155,
7186,
14903,
1963,
2,
1285,
3,
1837,
5282,
35,
36,
160,
6402
] | [
"Aged",
"Aged, 80 and over",
"Animals",
"Antibodies, Monoclonal, Humanized",
"Biomarkers, Tumor",
"Cachexia",
"Carcinoma, Lewis Lung",
"Carcinoma, Non-Small-Cell Lung",
"Female",
"Gene Expression Regulation, Neoplastic",
"Humans",
"Interleukin-6",
"Kaplan-Meier Estimate",
"Male",
"Mice",... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
10912845 | Does quantitative ultrasound imaging enhance precision and discrimination? | The aim of this study was to compare quantitative ultrasound (QUS) measurements obtained using a new calcaneal QUS imaging device with a conventional non-imaging device using fixed transducers. The study group consisted of 340 healthy women with no risk factors associated with osteoporosis (176 premenopausal and 164 po... | [
223,
9,
133,
437,
863,
186,
2,
3,
322,
160,
2061,
6895,
5974,
6735,
1932,
3934,
131,
1100
] | [
"Absorptiometry, Photon",
"Adult",
"Aged",
"Aging",
"Bone Density",
"Calcaneus",
"Female",
"Humans",
"Linear Models",
"Middle Aged",
"Multivariate Analysis",
"Osteoporosis, Postmenopausal",
"Postmenopause",
"Premenopause",
"Quality Control",
"Spinal Fractures",
"Time Factors",
"Ult... | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
2175039 | [Magnetic resonance tomography in hepatocellular carcinoma and idiopathic hemochromatosis]. | A case of hepatocellular carcinoma in idiopathic hemochromatosis is discussed to illustrate the possible advantages of MR imaging. Since hepatic iron overload provides a natural source of paramagnetic contrast enhancement MRI should performed in preference to other investigative procedures to detect small and curative ... | [
2374,
14543,
3,
2375,
188,
35,
160
] | [
"Carcinoma, Hepatocellular",
"Hemochromatosis",
"Humans",
"Liver Neoplasms",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
12483296 | Mitochondrial DNA polymorphisms associated with longevity in a Finnish population. | Sequence variation in mitochondrial DNA (mtDNA) may cause slight differences both in the functioning of the respiratory chain and in free radical production, and an association between certain mtDNA haplogroups and longevity has been suggested. In order to determine further the role of mtDNA in longevity, we studied th... | [
204,
9,
133,
310,
437,
895,
2,
1576,
1323,
898,
11548,
3,
14,
3248,
35,
160,
1035,
1444,
1865,
1588
] | [
"Adolescent",
"Adult",
"Aged",
"Aged, 80 and over",
"Aging",
"DNA, Mitochondrial",
"Female",
"Finland",
"Gene Frequency",
"Haplotypes",
"Hospital Records",
"Humans",
"Infant",
"Longevity",
"Male",
"Middle Aged",
"Phylogeny",
"Polymorphism, Genetic",
"Polymorphism, Restriction Fra... | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 1,
"N": 1,
"Z": 1
} |
32597130 | A cross sectional study of salt content in bakery bread in Zagreb, Croatia. | Reducing salt content in bread is the essential part of a national strategy for salt reduction with the goal of long-term national general health improvement. In this study we have analysed salt content in three types of bread available in 25 small and five national industrial bakeries in Zagreb, Croatia. Samples of wh... | [
7120,
1891,
12,
8749
] | [
"Bread",
"Croatia",
"Cross-Sectional Studies",
"Sodium Chloride, Dietary"
] | {
"A": 0,
"B": 0,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 0,
"N": 1,
"Z": 1
} |
2995373 | Purification and characterization of a smooth muscle myosin phosphatase from turkey gizzards. | A phosphoprotein phosphatase that dephosphorylates smooth muscle myosin has been purified to apparent homogeneity from turkey gizzards. Smooth muscle phosphatase (SMP) IV has a molecular weight of 150,000 as determined by gel filtration on a Sephadex G-200 column and is composed of two subunits (Mr = 58,000 and 40,000)... | [
30,
551,
4833,
305,
119,
39,
21440,
2232,
758,
10081
] | [
"Animals",
"Calcium",
"Gizzard, Avian",
"Kinetics",
"Magnesium",
"Muscle, Smooth",
"Myosin-Light-Chain Phosphatase",
"Phosphoprotein Phosphatases",
"Substrate Specificity",
"Turkeys"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
31981231 | CXCR2-modified CAR-T cells have enhanced trafficking ability that improves treatment of hepatocellular carcinoma. | Unlike hematological malignancies, solid tumors have proved to be less susceptible to chimeric antigen receptor (CAR)-T cell therapy, which is partially caused by reduced accumulation of therapeutic T cells in tumor site. Since efficient trafficking is the precondition and pivotal step for infused CAR-T cells to exhibi... | [
30,
2374,
389,
546,
5372,
21476,
6080,
441,
3,
13638,
5126,
2375,
36,
6278,
15154,
3629,
5640,
5109,
1291
] | [
"Animals",
"Carcinoma, Hepatocellular",
"Cell Line, Tumor",
"Cell Movement",
"Chemokine CCL2",
"Chemokine CXCL5",
"Cytotoxicity, Immunologic",
"Gene Expression",
"Humans",
"Immunotherapy, Adoptive",
"Interleukin-8",
"Liver Neoplasms",
"Mice",
"Receptors, Chimeric Antigen",
"Receptors, In... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
6129035 | Radioautographic investigation of monoaminergic neurons: an evaluation. | This review outlines the most relevant contributions currently available on the detection and ultrastructural characterization of monoaminergic neurons by radioautography after administration of radiolabeled monoamines. It includes methodological considerations and then a critical analysis of the diagnostic value of th... | [
16950,
30,
2363,
1640,
206,
1601,
1489,
1924,
7077,
1144,
5794,
1753,
43,
222
] | [
"Adrenergic Fibers",
"Animals",
"Autoradiography",
"Axons",
"Brain",
"Brain Mapping",
"Cats",
"Dopamine",
"Nerve Fibers",
"Neurons",
"Neurotransmitter Agents",
"Norepinephrine",
"Rats",
"Serotonin"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
6546564 | Luteinizing hormone secretion after withdrawal of exogenous progestogen in heifers fed three levels of dietary energy. | As experiment was conducted with 15 Angus X Hereford heifers that were 16 mo of age at the time the experiment was initiated. The heifers were assigned randomly in equal numbers to be fed low (L), maintenance (M) or high (H) energy diets for 191 d. Overall average weight for heifers at the time the experiment was initi... | [
30,
862,
424,
2011,
3836,
12288,
2368,
765,
3318,
2,
707,
20,
4280,
675
] | [
"Animals",
"Body Weight",
"Cattle",
"Diet",
"Drug Combinations",
"Drug Implants",
"Energy Metabolism",
"Estradiol",
"Estrus",
"Female",
"Luteinizing Hormone",
"Pregnancy",
"Pregnenediones",
"Progesterone"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
23007965 | De novo correction of mass measurement error in low resolution tandem MS spectra for shotgun proteomics. | We report an algorithm designed for the calibration of low resolution peptide mass spectra. Our algorithm is implemented in a program called FineTune, which corrects systematic mass measurement error in 1 min, with no input required besides the mass spectra themselves. The mass measurement accuracy for a set of spectra... | [
87,
1997,
716,
717,
8111,
3990,
4537,
98,
355
] | [
"Algorithms",
"Calibration",
"Models, Molecular",
"Peptide Fragments",
"Peptide Mapping",
"Proteomics",
"Saccharomyces cerevisiae Proteins",
"Sensitivity and Specificity",
"Tandem Mass Spectrometry"
] | {
"A": 0,
"B": 0,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 1,
"Z": 0
} |
19735863 | Radiation therapy for esophageal cancer in Japan: results of the Patterns of Care Study 1999-2001. | PURPOSE: To describe patient characteristics and the process of radiotherapy (RT) for patients with esophageal cancer treated between 1999 and 2001 in Japan.METHODS AND MATERIALS: The Japanese Patterns of Care Study (PCS) Working Group conducted a third nationwide survey of 76 institutions. Detailed information was acc... | [
1315,
133,
16237,
721,
1829,
1318,
2,
3590,
3,
2022,
35,
160,
1187,
925
] | [
"Adenocarcinoma",
"Aged",
"Carcinoma, Adenosquamous",
"Carcinoma, Squamous Cell",
"Combined Modality Therapy",
"Esophageal Neoplasms",
"Female",
"Health Care Surveys",
"Humans",
"Japan",
"Male",
"Middle Aged",
"Neoplasm Staging",
"Radiotherapy"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
6121730 | 17 alpha-hydroxylase deficiency in a genetic male and female sibling pair. | The diagnosis of congenital adrenal hyperplasia due to a deficiency of the enzyme 17 alpha-hydroxylase was made in a genetic male and female sibling pair born of parents who were first cousins. The genetic male was a phenotypic female who presented with primary amenorrhea and mild hypertension. The genetic female exhib... | [
204,
8219,
104,
1584,
5365,
207,
705,
2,
5593,
6579,
3,
35,
2717,
5775
] | [
"Adolescent",
"Adrenal Hyperplasia, Congenital",
"Child",
"Chromosome Aberrations",
"Chromosome Disorders",
"Diagnosis, Differential",
"Disorders of Sex Development",
"Female",
"Genes, Recessive",
"Gonadal Steroid Hormones",
"Humans",
"Male",
"Prednisone",
"Steroid Hydroxylases"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
31712332 | Association of the frequency of spicy food intake and the risk of abdominal obesity in rural Chinese adults: a cross-sectional study. | OBJECTIVES: Recent data relating to the association between spicy food intake frequency and abdominal obesity are limited, especially in low-income areas. Therefore, the study explored the relationship between spicy food intake frequency and abdominal obesity, and assessed the role of energy intake as a mediator of the... | [
9,
133,
591,
1440,
1812,
12,
2011,
2,
13849,
7329,
3,
1270,
35,
160,
4121,
1274,
1889,
177,
1383,
11850,
3163
] | [
"Adult",
"Aged",
"Body Mass Index",
"China",
"Cohort Studies",
"Cross-Sectional Studies",
"Diet",
"Female",
"Flavoring Agents",
"Food Preferences",
"Humans",
"Logistic Models",
"Male",
"Middle Aged",
"Obesity, Abdominal",
"Prevalence",
"Risk Assessment",
"Risk Factors",
"Rural He... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 1,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
26639652 | Effect of temporal and spatial variability on the classification of the Ecological Quality Status using the CARLIT Index. | Methodologies developed by European Member States to assess the environmental quality of their coastal waters under the EU Water Framework Directive (WFD, 2000/60/EC) may have an associated source of uncertainty. Here we identify and quantify the level of uncertainty in the CARLIT (Cartography of littoral and upper-sub... | [
6623,
1719,
319,
247,
1420,
97,
9194,
1631
] | [
"Ecology",
"Ecosystem",
"Environment",
"Environmental Monitoring",
"European Union",
"Reproducibility of Results",
"Uncertainty",
"Water Quality"
] | {
"A": 0,
"B": 0,
"C": 0,
"D": 0,
"E": 1,
"F": 1,
"G": 1,
"H": 1,
"I": 1,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
24552056 | Absolute dominance of hydrogenotrophic methanogens in full-scale anaerobic sewage sludge digesters. | Anaerobic digestion (AD) is gaining increasing attention due to the ability to covert organic pollutants into energy-rich biogas and, accordingly, growing interest is paid to the microbial ecology of AD systems. Despite extensive efforts, AD microbial ecology is still limitedly understood, especially due to the lack of... | [
2810,
2572,
14001,
1035,
4035
] | [
"Anaerobiosis",
"Bioreactors",
"Euryarchaeota",
"Phylogeny",
"Sewage"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
15572593 | Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor. | Glucocorticoids are among the most effective agents used in the treatment of childhood acute lymphoblastic leukemia (ALL), and patient response to treatment is an important determinant of long-term outcome. Despite its clinical significance, the molecular basis of glucocorticoid resistance in lymphoid malignancies is s... | [
10518,
204,
30,
1808,
193,
3245,
7352,
8603,
1331,
104,
105,
3224,
391,
2,
7208,
3,
1027,
35,
285,
36,
6277,
8730,
2112,
7594,
1302,
5094,
588,
6783
] | [
"Active Transport, Cell Nucleus",
"Adolescent",
"Animals",
"Antineoplastic Agents, Hormonal",
"Apoptosis",
"Apoptosis Regulatory Proteins",
"Bcl-2-Like Protein 11",
"Burkitt Lymphoma",
"Cell Nucleus",
"Child",
"Child, Preschool",
"Dexamethasone",
"Drug Resistance, Neoplasm",
"Female",
"G... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
11101274 | Matrix metalloproteinases and their endogenous inhibitors during the implantation period in the rat uterus. | Rats were studied to determine if matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) were detectable in developing embryonic and uterine tissues during the implantation period; that is, Days 6-8 of pregnancy. Tissue extracts were studied by zymography, reverse zymography and Western blotting. Immuno... | [
30,
611,
10439,
9311,
3056,
2447,
208,
2,
4,
9831,
8513,
5779,
3838,
3839,
20,
7105,
43,
245,
131,
5780,
8514,
20898,
12726,
686
] | [
"Animals",
"Blotting, Western",
"Decidua",
"Doxycycline",
"Electrophoresis",
"Embryo Implantation",
"Enzyme Inhibitors",
"Female",
"Immunohistochemistry",
"Matrix Metalloproteinase 1",
"Matrix Metalloproteinase 2",
"Matrix Metalloproteinase 9",
"Matrix Metalloproteinase Inhibitors",
"Matri... | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
26582830 | Usefulness of High-Quality Core Genome Single-Nucleotide Variant Analysis for Subtyping the Highly Clonal and the Most Prevalent Salmonella enterica Serovar Heidelberg Clone in the Context of Outbreak Investigations. | Salmonella enterica serovar Heidelberg is the second most frequently occurring serovar in Quebec and the third-most prevalent in Canada. Given that conventional pulsed-field gel electrophoresis (PFGE) subtyping for common Salmonella serovars, such as S. Heidelberg, yields identical subtypes for the majority of isolates... | [
2216,
3057,
1132,
1133,
220,
2054,
3,
5467,
634,
4460,
7495,
11458
] | [
"Disease Outbreaks",
"Electrophoresis, Gel, Pulsed-Field",
"Genome, Bacterial",
"Genomics",
"Genotype",
"High-Throughput Nucleotide Sequencing",
"Humans",
"Molecular Typing",
"Polymorphism, Single Nucleotide",
"Quebec",
"Salmonella Infections",
"Salmonella enterica"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 1
} |
9146356 | Mitral homograft replacement of the tricuspid valve for endocarditis. | An infected tricuspid valve was successfully replaced with a fresh mitral homograft. This operation is preferable to valvectomy alone or the use of a stented prosthesis in terms of hemodynamics and resistance to infection. | [
3444,
2,
3,
160,
3447,
436,
6297,
5157
] | [
"Endocarditis",
"Female",
"Humans",
"Middle Aged",
"Mitral Valve",
"Transplantation, Homologous",
"Tricuspid Valve",
"Tricuspid Valve Insufficiency"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
21745270 | Matrix metalloproteinase 2 genotype is associated with nonanastomotic biliary strictures after orthotopic liver transplantation. | BACKGROUND: Nonanastomotic biliary strictures (NAS) are a serious complication after orthotopic liver transplantation (OLT). Matrix metalloproteinases (MMPs) are involved in connective tissue remodelling in chronic liver disease and complications after OLT.AIM: To evaluate the relationship between MMP-2 and MMP-9 gene ... | [
204,
9,
133,
529,
12241,
457,
231,
2,
1323,
1880,
3,
5282,
2276,
1270,
35,
8513,
5779,
160,
946,
1444,
1428,
1814,
189,
1889,
177,
131,
144,
27
] | [
"Adolescent",
"Adult",
"Aged",
"Chi-Square Distribution",
"Cholangitis, Sclerosing",
"Cholestasis",
"Constriction, Pathologic",
"Female",
"Gene Frequency",
"Genetic Predisposition to Disease",
"Humans",
"Kaplan-Meier Estimate",
"Liver Transplantation",
"Logistic Models",
"Male",
"Matri... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
785889 | [Comparative study of group A streptococcal antigens. II. Comparative characteristics of several physico-chemical and immunochemical properties of partially purified M-protein and cytoplasmic protective antigen]. | The authors carried out a comparative physico-chemical and immunochemical study of antigen obtained from the fraction of streptococcus cytoplasm by precipitation with ammonium sulfate, and partially purified M-protein. They proved to be heterogeneous by molecular-weight characteristics when tested by the methods of sed... | [
5088,
7416,
5274,
768,
1532,
4257,
3391,
6675
] | [
"Antigens, Bacterial",
"Cell Wall",
"Electrophoresis, Disc",
"Immunoelectrophoresis",
"Molecular Weight",
"Precipitin Tests",
"Spectrophotometry",
"Streptococcus pyogenes"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8351100 | Orbital retractors for posterior segment surgery. | Successful retinal detachment surgery is greatly aided by proper visualization of and access to the intended surgical field. Two retractors, one having a single blade and the other a double blade, have been developed to aid retinal detachment surgery. | [
3,
9531,
8464,
3262,
13964
] | [
"Humans",
"Ophthalmology",
"Orbit",
"Retinal Detachment",
"Scleral Buckling"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
28828215 | Cortical thickness and subcortical structure volume abnormalities in patients with major depression with and without anxious symptoms. | BACKGROUND: Anxious depression is one of the common subtypes of major depressive disorder (MDD). Clinically, patients with anxious depression exhibit more severe depressive symptoms than patients with nonanxious depression. The aim of the present study was to explore the common and differing cortical and subcortical st... | [
9,
637,
3615,
2365,
638,
1197,
7781,
2,
241,
3,
188,
35,
160,
870,
5334
] | [
"Adult",
"Anxiety",
"Caudate Nucleus",
"Cerebral Cortex",
"Depression",
"Depressive Disorder, Major",
"Diagnostic and Statistical Manual of Mental Disorders",
"Female",
"Hippocampus",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Organ Size",
"Statistics as Topic"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 0,
"E": 1,
"F": 1,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 1,
"M": 1,
"N": 1,
"Z": 0
} |
17002878 | Expression and characterization of RNA-dependent RNA polymerase of Dendrolimus punctatus tetravirus. | Dendrolimus punctatus tetravirus (DpTV) has been identified as a new member of the genus Omegatetravirus of the family Tetraviridae that may be related serologically to Nudaurelia capensis virus (NomegaV). To establish the function of DpTV RNA genome and to better understand the mechanism of viral replication, the puta... | [
28,
439,
1686,
611,
2475,
1034,
13381,
37,
666,
1036,
1037,
16399,
506,
635,
2155,
1040
] | [
"Amino Acid Sequence",
"Base Sequence",
"Blotting, Northern",
"Blotting, Western",
"DNA, Complementary",
"Genome, Viral",
"Insect Viruses",
"Molecular Sequence Data",
"Mutation",
"RNA Viruses",
"RNA, Viral",
"RNA-Dependent RNA Polymerase",
"Recombinant Proteins",
"Reverse Transcriptase Pol... | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
20815792 | Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections. | PURPOSE: The efficacy of aerosolization of ciprofloxacin (CPFX) incorporated into PEGylated liposomes (PEGylated CPFX-liposomes) for the treatment of respiratory infections was evaluated.METHOD: PEGylated CPFX-liposomes with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-n-[methoxy(polyethylene glycol)-2000] (particle... | [
3939,
30,
2331,
729,
2831,
1914,
2846,
2068,
1415,
814,
35,
1918,
43,
69,
1538
] | [
"Aerosols",
"Animals",
"Anti-Infective Agents",
"Area Under Curve",
"Ciprofloxacin",
"Drug Delivery Systems",
"Epithelium",
"L-Lactate Dehydrogenase",
"Liposomes",
"Lung",
"Male",
"Polyethylene Glycols",
"Rats",
"Rats, Sprague-Dawley",
"Respiratory Tract Infections"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
16362901 | Evaluating distance functions for clustering tandem repeats. | Tandem repeats are an important class of DNA repeats and much research has focused on their efficient identification, their use in DNA typing and fingerprinting, and their causative role in trinucleotide repeat diseases such as Huntington Disease, myotonic dystrophy, and Fragile-X mental retardation. We are interested ... | [
87,
439,
2672,
2133,
3005,
31,
7548,
3,
97,
2916,
4327
] | [
"Algorithms",
"Base Sequence",
"Chromosome Mapping",
"Cluster Analysis",
"Computational Biology",
"Consensus Sequence",
"Entropy",
"Humans",
"Reproducibility of Results",
"Sequence Homology, Nucleic Acid",
"Tandem Repeat Sequences"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 1,
"Z": 0
} |
712956 | Undetected tuberculosis in prison. Source of infection for community at large. | Discovery of two cases of infectious tuberculosis in a state prison in 1976 prompted a careful study of the entire population of 1,500. Eight more cases were found, giving a morbidity of 670/100,000 (arkansas rate, 21.1). The epidemic was aborted by the use of isoniazid and the establishment of a program for screening ... | [
20307,
3,
7424,
6070,
482,
1439,
132
] | [
"Arkansas",
"Humans",
"Isoniazid",
"Prisoners",
"Quality of Health Care",
"Tuberculosis, Pulmonary",
"United States"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
20148327 | Epidemiology and imaging of the subchondral bone in articular cartilage repair. | Articular cartilage and the subchondral bone act as a functional unit. Following trauma, osteochondritis dissecans, osteonecrosis or osteoarthritis, this intimate connection may become disrupted. Osteochondral defects-the type of defects that extend into the subchondral bone-account for about 5% of all articular cartil... | [
403,
185,
696,
2560,
7515,
3,
188,
2355,
4666,
10983,
9076,
1236,
1099
] | [
"Arthroscopy",
"Bone Transplantation",
"Bone and Bones",
"Cartilage, Articular",
"Chondrocytes",
"Humans",
"Magnetic Resonance Imaging",
"Orthopedic Procedures",
"Osteoarthritis",
"Osteochondritis Dissecans",
"Osteonecrosis",
"Radionuclide Imaging",
"Tomography, X-Ray Computed"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
26849100 | Estrous cycle synchronization in the Persian onager (Equus hemionus onager). | The endangered Persian onager (Equus hemionus onager) has experienced significant population declines over the past century due to poaching, habitat destruction, and resource competition. Remaining animals in zoos and the wild are regionally isolated. Artificial insemination (AI) may be particularly useful as a means o... | [
30,
9814,
6784,
16500,
669,
2,
672,
1100
] | [
"Animals",
"Animals, Zoo",
"Endangered Species",
"Equidae",
"Estrus Synchronization",
"Female",
"Insemination, Artificial",
"Ultrasonography"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
7263134 | The poorly coping COPD patient: a psychotherapeutic perspective. | An etiology of maladaptive coping in Chronic Obstructive Pulmonary Disease is proposed and a model for psychotherapeutic intervention with poorly coping COPD patients is presented. Failure in mourning, manifested by a lack of shift in patient's expectations and goals leads to: 1) difficulty in accepting illness related... | [
475,
2093,
5114,
7492,
3,
7689,
1202
] | [
"Adaptation, Psychological",
"Behavior Therapy",
"Family Therapy",
"Grief",
"Humans",
"Lung Diseases, Obstructive",
"Psychotherapy"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 0,
"F": 1,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
28283188 | Targeted cytoplasmic irradiation and autophagy. | The effect of ionizing irradiation on cytoplasmic organelles is often underestimated because the general dogma considers direct DNA damage in the nuclei to be the primary cause of radiation induced toxicity. Using a precision microbeam irradiator, we examined the changes in mitochondrial dynamics and functions triggere... | [
15213,
193,
3246,
51,
1641,
1498,
3,
21145,
364,
3536,
400
] | [
"Alpha Particles",
"Apoptosis",
"Autophagy",
"Cells, Cultured",
"Cytoplasm",
"Epithelial Cells",
"Humans",
"Mitochondrial Dynamics",
"Reactive Oxygen Species",
"Respiratory System",
"TOR Serine-Threonine Kinases"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
31839083 | Comparison of the Effects of Ultrasound-guided Erector Spinae Plane Block and Wound Infiltration on Perioperative Opioid Consumption and Postoperative Pain in Thoracotomy. | OBJECTIVE: To compare the effects of preoperative ultrasound-guided erector spinae plane block (ESPB) and preoperative wound infiltration on perioperative opioid consumption and postoperative pain in thoracotomy.STUDY DESIGN: Randomised controlled trial.PLACE AND DURATION OF STUDY: Department of Anesthesiology, Cancer ... | [
13974,
29,
2,
3,
35,
160,
60,
6379,
42,
110,
7052,
1941,
3265,
2558,
1100
] | [
"Analgesia, Patient-Controlled",
"Analgesics, Opioid",
"Female",
"Humans",
"Male",
"Middle Aged",
"Muscle, Skeletal",
"Nerve Block",
"Pain Measurement",
"Pain, Postoperative",
"Perioperative Period",
"Therapy, Computer-Assisted",
"Thoracic Vertebrae",
"Thoracotomy",
"Ultrasonography"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 1,
"N": 1,
"Z": 0
} |
18204905 | Quantitative measurement of protease ligand conformation. | The tendency for protease ligands to bind in an extended conformation has been suggested as an important factor for the identification of compounds of medicinal importance. Here we present a novel graph-theoretical method giving a quantitative measure of ligand conformation, and through application of this method to a ... | [
1027,
716,
1399,
370
] | [
"Ligands",
"Models, Molecular",
"Molecular Conformation",
"Peptide Hydrolases"
] | {
"A": 0,
"B": 0,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
24050534 | 3C protein of feline coronavirus inhibits viral replication independently of the autophagy pathway. | Feline coronavirus (FCoV) can cause either asymptomatic enteric infection or fatal peritonitis in cats. Although the mutation of FCoV accessory gene 3c has been suggested to be related to the occurrence of feline infectious peritonitis (FIP), how the 3C protein is involved in this phenomenon remains unknown. To investi... | [
30,
3246,
1489,
51,
10676,
10677,
850,
10678,
2,
35,
2050,
1040
] | [
"Animals",
"Autophagy",
"Cats",
"Cells, Cultured",
"Coronavirus 3C Proteases",
"Coronavirus, Feline",
"Cysteine Endopeptidases",
"Feline Infectious Peritonitis",
"Female",
"Male",
"Virulence",
"Virus Replication"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
25416685 | Reconceptualizing successful aging among black women and the relevance of the strong black woman archetype. | Although there are multiple pathways to successful aging, little is known of what it means to age successfully among black women. There is a growing body of literature suggesting that black women experience a number of social challenges (sexism and racism) that may present as barriers to aging successfully. Applying as... | [
475,
9,
1196,
5912,
437,
2,
9849,
984,
3,
1605,
2889,
483,
10186
] | [
"Adaptation, Psychological",
"Adult",
"African Americans",
"African Continental Ancestry Group",
"Aging",
"Female",
"Geriatrics",
"Health Status",
"Humans",
"Mental Disorders",
"Mental Health",
"Quality of Life",
"Resilience, Psychological"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 0,
"F": 1,
"G": 1,
"H": 1,
"I": 1,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
1938098 | Central glucocorticoid regulation of parasympathetic drive to pancreatic B-cells in the obese fa/fa rat. | The effects of glucocorticoids on the insulin secretory response to an intravenous glucose load have been studied in lean (Fa/?) and obese fa/fa Zucker rats. The role of parasympathetic drive to the pancreatic B-cells was assessed as that component of the insulin secretory response that was blocked by pretreatment of t... | [
10364,
30,
736,
206,
4390,
698,
1520,
741,
35,
596,
5517,
43,
7021,
5094,
6780
] | [
"Adrenalectomy",
"Animals",
"Blood Glucose",
"Brain",
"Glucocorticoids",
"Insulin",
"Insulin Resistance",
"Islets of Langerhans",
"Male",
"Obesity",
"Parasympathetic Nervous System",
"Rats",
"Rats, Zucker",
"Receptors, Glucocorticoid",
"Vagus Nerve"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
9029027 | Hypereosinophilic syndrome in a child mosaic for a congenital triplication of the short arm of chromosome 8. | An 11-year-old boy with mental retardation, malformations, and the mosaic karyotype 47,XY,+i(8p)/46,XY presented with fever, headache and petechiae. Peripheral blood WBC was 190 x 10(9)/l; and contained > 90% mature eosinophils. Cytogenetic analysis of the eosinophils revealed no aberrations except the constitutional k... | [
104,
2674,
12847,
1616,
2002,
3,
11889,
334,
35,
286,
7804,
337
] | [
"Child",
"Chromosomes, Human, Pair 8",
"Coronary Thrombosis",
"Eosinophils",
"Fatal Outcome",
"Humans",
"Hypereosinophilic Syndrome",
"Karyotyping",
"Male",
"Microscopy, Electron",
"Mosaicism",
"Trisomy"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
18065545 | Phage response to CRISPR-encoded resistance in Streptococcus thermophilus. | Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated genes are linked to a mechanism of acquired resistance against bacteriophages. Bacteria can integrate short stretches of phage-derived sequences (spacers) within CRISPR loci to become phage resistant. In this study, we further chara... | [
439,
1071,
3212,
1,
1132,
1034,
369,
1624,
37,
5143,
2916,
21374,
9991
] | [
"Base Sequence",
"DNA, Bacterial",
"DNA, Intergenic",
"DNA, Viral",
"Genome, Bacterial",
"Genome, Viral",
"Host-Pathogen Interactions",
"Models, Genetic",
"Molecular Sequence Data",
"Repetitive Sequences, Nucleic Acid",
"Sequence Homology, Nucleic Acid",
"Streptococcus Phages",
"Streptococcu... | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
29633941 | Transcatheter treatment of tricuspid regurgitation using edge-to-edge repair: procedural results, clinical implications and predictors of success. | AIMS: The aim of this study was to analyse the feasibility, safety and effectiveness of tricuspid valve (TV) repair using the MitraClip system in patients at high surgical risk.METHODS AND RESULTS: Forty-two elderly high-risk patients (76.8±7.3 years, EuroSCORE II 8.1±5.7) with isolated TR or combined TR and mitral reg... | [
133,
310,
5156,
3,
3447,
144,
5157
] | [
"Aged",
"Aged, 80 and over",
"Heart Valve Prosthesis Implantation",
"Humans",
"Mitral Valve",
"Treatment Outcome",
"Tricuspid Valve Insufficiency"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
26564517 | [Application of Reporter Gene Labeling in Stem Cell Therapy for Acute Myocardial Infarction]. | Stem cell therapy for acute myocardial infarction is drawing great attention. However,the biological behavior and function mechanism of implanted stem cells remain controversial, as well as their clinical benefits. With the development of imaging probes and devices, molecular imaging enables noninvasive, dynamic tracki... | [
3354,
2419,
3,
1404,
3227
] | [
"Genes, Reporter",
"Genetic Therapy",
"Humans",
"Myocardial Infarction",
"Stem Cell Transplantation"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
16905066 | Search and selection methodology of systematic reviews in orthodontics (2000-2004). | INTRODUCTION: More systematic reviews related to orthodontic topics are published each year, although little has been done to evaluate their search and selection methodologies.METHODS: Systematic reviews related to orthodontics published between January 1, 2000, and December 31, 2004, were searched for their use of mul... | [
11356,
15421,
3,
2134,
8475,
6156,
8085
] | [
"Databases, Bibliographic",
"Dental Informatics",
"Humans",
"Information Storage and Retrieval",
"Meta-Analysis as Topic",
"Orthodontics",
"Review Literature as Topic"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 1,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 1,
"Z": 0
} |
9868651 | An EORTC international multicenter randomized trial (EORTC number 19923) comparing two dosages of liposomal amphotericin B for treatment of invasive aspergillosis. | This is the first completed prospective randomized clinical efficacy trial of antifungals in the treatment of invasive aspergillosis (IA) and the first to compare the clinical efficacy of two dosages of liposomal amphotericin B (L-AmB) for IA in neutropenic patients with cancer or those undergoing bone marrow transplan... | [
9,
133,
1413,
728,
1414,
77,
2,
3,
1415,
35,
160,
111,
542,
144
] | [
"Adult",
"Aged",
"Amphotericin B",
"Antifungal Agents",
"Aspergillosis",
"Drug Carriers",
"Female",
"Humans",
"Liposomes",
"Male",
"Middle Aged",
"Prospective Studies",
"Survival Analysis",
"Treatment Outcome"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
17880150 | Slow recrystallization of tripalmitoylglycerol from MCT oil observed by 2H NMR. | The crystallization and recrystallization of fats have a significant impact on the properties and quality of many food products. While crystallization has been the subject of a number of studies using pure triacylglycerols (TAG), recrystallization in similarly pure systems is rarely studied. In this work, perdeuterated... | [
1243,
712,
854,
713,
2948,
720,
1088
] | [
"Crystallization",
"Deuterium",
"Hot Temperature",
"Magnetic Resonance Spectroscopy",
"Oils",
"Solutions",
"Triglycerides"
] | {
"A": 0,
"B": 0,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
3066888 | Evaluation of four modalities of periodontal therapy. Mean probing depth, probing attachment level and recession changes. | Eighty-two periodontally involved patients were treated in a split mouth design such that one quadrant received coronal scaling (CS), root planing (RP), modified Widman surgery (MW), and flap with osseous resection surgery (FO). The therapy was performed in three phases: Phase I: the teeth previously designated to rece... | [
9,
15633,
14705,
1205,
2,
2206,
7828,
3,
379,
35,
1381,
14853,
7207,
14706,
1188,
4434,
12522
] | [
"Adult",
"Dental Scaling",
"Epithelial Attachment",
"Evaluation Studies as Topic",
"Female",
"Gingival Diseases",
"Gingival Recession",
"Humans",
"Longitudinal Studies",
"Male",
"Periodontal Diseases",
"Periodontal Pocket",
"Periodontitis",
"Periodontium",
"Random Allocation",
"Surgica... | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
9190969 | Epidermal growth factor receptor in vulvar malignancies and its relationship to metastasis and patient survival. | OBJECTIVE: To evaluate the level of epidermal growth factor receptor (EGF-R) expression in vulvar malignancies and to determine if a correlation exists between EGF-R levels and metastasis or patient survival.METHODS: All patients with a diagnosis of invasive squamous cell carcinoma of the vulva who were treated at our ... | [
721,
2407,
3352,
2,
3,
1850,
143,
8332
] | [
"Carcinoma, Squamous Cell",
"Disease-Free Survival",
"ErbB Receptors",
"Female",
"Humans",
"Lymphatic Metastasis",
"Survival Rate",
"Vulvar Neoplasms"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
11959849 | Proteasome inhibitors reduce luciferase and beta-galactosidase activity in tissue culture cells. | Reporter enzymes are commonly used in cell biology to study transcriptional activity of genes. Recently, reporter enzymes in combination with compounds that inhibit proteasome function have been used to study the effect of blocking transcription factor degradation on gene activation. While investigating the effect of p... | [
850,
3542,
3354,
2385,
2147,
1644,
635,
1284,
5733
] | [
"Cysteine Endopeptidases",
"Cysteine Proteinase Inhibitors",
"Genes, Reporter",
"Luciferases",
"Multienzyme Complexes",
"Proteasome Endopeptidase Complex",
"Reverse Transcriptase Polymerase Chain Reaction",
"Tumor Cells, Cultured",
"beta-Galactosidase"
] | {
"A": 1,
"B": 0,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
3312077 | Growth of retinal capillary endothelia using pericyte conditioned medium. | Long-term cultures of bovine retinal capillary endothelial cells (BRCEC) have been established using bovine retinal pericyte conditioned medium (PCM). PCM had greater mitogenic activity on BRCEC than unconditioned medium (P less than 0.01). The mitogenic activity of PCM was not cell specific since bovine Tenon's fibrob... | [
30,
3231,
424,
51,
3067,
6522,
2846,
3695
] | [
"Animals",
"Capillaries",
"Cattle",
"Cells, Cultured",
"Culture Media",
"Cytological Techniques",
"Epithelium",
"Retinal Vessels"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
15796893 | Involvement of lipid peroxidation in the degradation of a non-phenolic lignin model compound by manganese peroxidase of the litter-decomposing fungus Stropharia coronilla. | Culture liquids of the litter-decomposing basidiomycete Stropharia coronilla showed pro-oxidant activity promoting the peroxidation of linoleic acid. This activity depended on the presence of manganese peroxidase (MnP) in the fungal culture. Pro-oxidant activity maxima coincided with maximum MnP activities during the s... | [
648,
3067,
1660,
2299,
378,
5062,
364
] | [
"Basidiomycota",
"Culture Media",
"Hydrolysis",
"Lignin",
"Lipid Peroxidation",
"Peroxidases",
"Reactive Oxygen Species"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8291295 | [Extraction of a ruptured PTCA balloon catheter]. | While attempting angioplasty of a very tight and long circumflex lesion with a metal-shafted monorail catheter, the flexible part of the balloon catheter shaft broke off within the guiding catheter. The lost piece of catheter was then retrieved from the coronary artery by using an on-the-wire balloon catheter that was ... | [
3469,
1232,
1233,
88,
3273,
2,
7292,
3,
160
] | [
"Angioplasty, Balloon, Coronary",
"Coronary Disease",
"Coronary Vessels",
"Equipment Design",
"Equipment Failure",
"Female",
"Foreign Bodies",
"Humans",
"Middle Aged"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
28635908 | [Idiopatic pulmonary fibrosis: A new paradigm]. | Idiopathic pulmonary fibrosis ((IPF) is the most common disease from a group of interstitial lung diseases, which occurs mainly in middle-aged and elderly people. Over the past decade, there have been considerable changes in approaches to diagnosing and treating IPF. The paper presents an update on the epidemiology of ... | [
133,
3,
1803,
5012,
160,
948
] | [
"Aged",
"Humans",
"Idiopathic Pulmonary Fibrosis",
"Lung Diseases, Interstitial",
"Middle Aged",
"Pulmonary Fibrosis"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
3897571 | Differences in cell-to-cell spread of pathogenic and apathogenic rabies virus in vivo and in vitro. | Pathogenic parental rabies virus and apathogenic variant virus were shown to differ in their ability to infect neurons in vivo and neuroblastoma cells in vitro. After intracerebral inoculation, the distribution of infected neurons in the brain was similar for both viruses, but the rate of spread throughout the brain, t... | [
30,
51,
4364,
1051,
922,
36,
1144,
3889,
9236,
376,
1040
] | [
"Animals",
"Cells, Cultured",
"Cerebellum",
"Cricetinae",
"Immunoenzyme Techniques",
"Mice",
"Neurons",
"Rabies virus",
"Receptors, Virus",
"Viral Proteins",
"Virus Replication"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
21384343 | Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. | Tumor angiogenesis is necessary for solid tumor progression and metastasis. Cyclooxygenase (COX)-2 is known to play an important role in cancer growth and invasion, and it activates the signaling pathways controlling cell proliferation, migration, apoptosis, and angiogenesis. COX-2 is reported to be expressed in many c... | [
30,
611,
546,
72,
51,
2310,
5275,
3234,
2,
3,
1826,
36,
448,
2122,
3691,
3713,
452,
620,
549,
2630
] | [
"Animals",
"Blotting, Western",
"Cell Movement",
"Cell Proliferation",
"Cells, Cultured",
"Cyclooxygenase 2",
"Cyclooxygenase 2 Inhibitors",
"Endothelium, Vascular",
"Female",
"Humans",
"Melanoma",
"Mice",
"Mice, Nude",
"Mouth Neoplasms",
"Neovascularization, Pathologic",
"Nitrobenzene... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
20334664 | Combined analysis of endometrial thickness and pattern in predicting outcome of in vitro fertilization and embryo transfer: a retrospective cohort study. | OBJECTIVE: To evaluate the combined effect of endometrial thickness and pattern on clinical outcome in patients undergoing in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET).METHODS: Cycles of IVF/ICSI-ET conducted between January 2003 and December 2008 at a university-based repro... | [
9,
6050,
1812,
1451,
2448,
5991,
2,
2431,
3,
2449,
4727,
870,
20,
2450,
397,
598,
144,
1100,
27
] | [
"Adult",
"Chorionic Gonadotropin",
"Cohort Studies",
"Drug Administration Schedule",
"Embryo Transfer",
"Endometrium",
"Female",
"Fertilization in Vitro",
"Humans",
"Infertility, Female",
"Menstrual Cycle",
"Organ Size",
"Pregnancy",
"Pregnancy Rate",
"Prognosis",
"Retrospective Studie... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
24225653 | The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates. | Vacuolar-type H(+) ATPases (V-ATPases) are multimeric protein complexes that play a universal role in the acidification of intracellular compartments in eukaryotic cells. We have isolated the recessive medaka mutation tintachina (tch), which carries an inactivating modification of the conserved glycine residue (G75R) o... | [
30,
2132,
37,
666,
8624,
956,
6812,
13419,
13203
] | [
"Animals",
"Biological Evolution",
"Molecular Sequence Data",
"Mutation",
"Oryzias",
"Phenotype",
"Protein Subunits",
"Vacuolar Proton-Translocating ATPases",
"Vertebrates"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
29895576 | Central nervous system blast crisis of chronic myeloid leukaemia misdiagnosed as tubercular meningitis. | Chronic Myeloid Leukaemia (CML) presenting with isolated Central Nervous System (CNS) blast crisis is an uncommon entity. A 22-year-old man, diagnosed with chronic phase CML in 2011 and was in haematological and cytogenetic remission until July 2016, had acute onset headache and vomiting with meningeal signs and was ad... | [
9,
4437,
12011,
781,
2341,
14299,
2213,
15576,
5482,
3,
3476,
8226,
35,
12207,
144,
4440
] | [
"Adult",
"Antitubercular Agents",
"Blast Crisis",
"Central Nervous System",
"Diagnostic Errors",
"Drug Therapy",
"Fever",
"Granulocyte Precursor Cells",
"Headache",
"Humans",
"Injections, Spinal",
"Leukemia, Myelogenous, Chronic, BCR-ABL Positive",
"Male",
"Rare Diseases",
"Treatment Out... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
29643477 | Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA. | Whilst 5-methylcytosine (5mC) is a major epigenetic mark in the nuclear DNA in mammals, whether or not mitochondrial DNA (mtDNA) receives 5mC modification remains controversial. Herein, we exhaustively analysed mouse mtDNA using three methods that are based upon different principles for detecting 5mC. Next-generation b... | [
8953,
30,
1105,
8954,
895,
3167,
427,
36,
6474
] | [
"5-Methylcytosine",
"Animals",
"Brain Chemistry",
"Chemistry Techniques, Analytical",
"DNA, Mitochondrial",
"Embryonic Stem Cells",
"Liver",
"Mice",
"Molecular Biology"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
10966718 | Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: clinical importance. | PURPOSE: To assess the outcome of papillary lesions, radial scars, or lobular carcinoma in situ (LCIS) diagnosed at stereotactic core-needle biopsy (SCNB).MATERIALS AND METHODS: Retrospective review of 1,236 lesions sampled with SCNB yielded 22 papillary lesions, nine radial scars, and five LCIS lesions. Diffuse lesion... | [
9,
133,
1786,
5079,
9346,
388,
1809,
7961,
8431,
207,
2,
3,
3625,
160,
4394,
598
] | [
"Adult",
"Aged",
"Biopsy, Needle",
"Breast",
"Breast Diseases",
"Breast Neoplasms",
"Carcinoma in Situ",
"Carcinoma, Lobular",
"Cicatrix",
"Diagnosis, Differential",
"Female",
"Humans",
"Mammography",
"Middle Aged",
"Papilloma",
"Retrospective Studies"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
11349453 | Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 2). Testicular toxicity in rats treated orally with ethinylestradiol for 2 weeks. | Parameters of ethinylestradiol-induced testicular toxicity were evaluated with organ weight determination, histopathological examination and quantitative morphometry. Male Sprague-Dawley rats were administered ethinylestradiol orally at 3 or 10 mg/kg/day for 2 weeks and 3 mg/kg/day for 4 weeks. Final body weights in al... | [
461,
30,
193,
862,
1226,
7481,
6045,
922,
2636,
35,
870,
6128,
2391,
43,
69,
12289,
709,
2042
] | [
"Administration, Oral",
"Animals",
"Apoptosis",
"Body Weight",
"DNA",
"Estradiol Congeners",
"Ethinyl Estradiol",
"Immunoenzyme Techniques",
"In Situ Nick-End Labeling",
"Male",
"Organ Size",
"Proliferating Cell Nuclear Antigen",
"Prostate",
"Rats",
"Rats, Sprague-Dawley",
"Seminal Ves... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8685209 | Ovarian, peritoneal, and endometrial serous carcinoma: clonal origin of multifocal disease. | The clonality of disseminated serous carcinoma involving the ovary, peritoneum, and, occasionally, the endometrium is controversial. Histopathologic examination alone cannot unequivocally distinguish between a monoclonal origin and a multicentric origin. Two patients with peritoneal serous carcinoma with minimal ovaria... | [
133,
11159,
1892,
2,
3,
160,
666,
1286,
5799,
1345
] | [
"Aged",
"Cystadenocarcinoma, Serous",
"Endometrial Neoplasms",
"Female",
"Humans",
"Middle Aged",
"Mutation",
"Ovarian Neoplasms",
"Peritoneal Neoplasms",
"Polymorphism, Single-Stranded Conformational"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
16905577 | Differential effect of methotrexate on the increased CCR2 density on circulating CD4 T lymphocytes and monocytes in active chronic rheumatoid arthritis, with a down regulation only on monocytes in responders. | OBJECTIVES: To evaluate the effect of orally administered methotrexate (MTX) on the density of CC chemokine receptor 2 (CCR2) and CXC chemokine receptor 3 (CXCR3) on circulating monocytes, and the coexpression of CXCR3 and CCR2 on CD4 T lymphocytes in patients with active chronic rheumatoid arthritis.METHODS: All 34 pa... | [
9,
133,
3798,
1552,
1655,
761,
1959,
1451,
2,
197,
163,
3,
2748,
2735,
35,
213,
160,
2084,
12459,
19357,
5675,
541
] | [
"Adult",
"Aged",
"Antirheumatic Agents",
"Arthritis, Rheumatoid",
"CD4-Positive T-Lymphocytes",
"Case-Control Studies",
"Chronic Disease",
"Drug Administration Schedule",
"Female",
"Flow Cytometry",
"Follow-Up Studies",
"Humans",
"Immunophenotyping",
"Lipopolysaccharide Receptors",
"Male... | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
27396242 | Effects of thrombin on insulin signalling and glucose uptake in cultured human myotubes. | BACKGROUND: Hyper-coagulability (elevated thrombin) is a feature of type 2 diabetes and contributes to an increased risk of thrombotic and vascular events. Skeletal muscle is the key peripheral tissue site of insulin resistance in type 2 diabetes. Cultured human skeletal muscle cells were used to explore the effects of... | [
13608,
51,
1778,
2369,
3,
698,
501,
2629,
4217,
588,
4345
] | [
"Adenylate Kinase",
"Cells, Cultured",
"Diabetes Mellitus, Type 2",
"Glucose",
"Humans",
"Insulin",
"Muscle Fibers, Skeletal",
"Protein Kinase C",
"Proto-Oncogene Proteins c-akt",
"Signal Transduction",
"Thrombin"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
15568700 | Developmental validation of a single-tube amplification of the 13 CODIS STR loci, D2S1338, D19S433, and amelogenin: the AmpFlSTR Identifiler PCR Amplification Kit. | Analysis of length polymorphism at short tandem repeat (STR) loci utilizing the polymerase chain reaction (PCR) process has proven to be an ideal assay for human identification purposes. The short length of STR loci coupled with the amplification of target sequence through PCR allows for a robust, sensitive, and specif... | [
30,
154,
1489,
424,
2904,
10412,
440,
11821,
146,
220,
1519,
3,
1114,
3094,
36,
449,
1444,
1860,
1336,
1722,
572,
4327,
653,
9410
] | [
"Animals",
"Bacteria",
"Cats",
"Cattle",
"Chickens",
"DNA Fingerprinting",
"DNA Primers",
"Deoxyribonucleotides",
"Dogs",
"Genotype",
"Horses",
"Humans",
"Indicators and Reagents",
"Magnesium Chloride",
"Mice",
"Polymerase Chain Reaction",
"Polymorphism, Genetic",
"Potassium Chlori... | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 1,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 0
} |
8952327 | [A population survey on bone mineral density in a fishing village in Wakayama Prefecture (Part 2); The analysis of the risk factors affecting the bone mineral density]. | The purpose of this study was to detect factors affecting lumbar bone mineral density (BMD) of general inhabitants in a rural community. A cohort consisting of 2261 inhabitants aged 40-79 years was set up based on the resident registration in Taiji town, Wakayama Prefecture in 1992. Fifty men and 50 women in each of fo... | [
204,
9,
133,
225,
863,
1812,
1309,
1177,
2,
14320,
3,
2022,
35,
160,
1272,
20,
177,
643
] | [
"Adolescent",
"Adult",
"Aged",
"Body Composition",
"Bone Density",
"Cohort Studies",
"Diabetes Mellitus",
"Exercise",
"Female",
"Fisheries",
"Humans",
"Japan",
"Male",
"Middle Aged",
"Population Surveillance",
"Pregnancy",
"Risk Factors",
"Rural Population"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 1,
"J": 1,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
1580296 | Compliance with zidovudine therapy in patients infected with human immunodeficiency virus, type 1: a cross-sectional study in a municipal hospital clinic. | PURPOSE: To determine the extent of and clinical variables associated with zidovudine compliance.PATIENTS AND METHODS: A survey of 83 patients infected with human immunodeficiency virus (HIV) followed in a municipal hospital clinic was performed. Compliance histories were validated by serum and urine zidovudine levels.... | [
15832,
3911,
9,
961,
8023,
12,
2,
3314,
13755,
3,
35,
160,
10712,
3487,
9141,
6916
] | [
"AIDS-Related Complex",
"Acquired Immunodeficiency Syndrome",
"Adult",
"Attitude to Health",
"Boston",
"Cross-Sectional Studies",
"Female",
"HIV-1",
"Hospitals, Municipal",
"Humans",
"Male",
"Middle Aged",
"Outpatient Clinics, Hospital",
"Patient Compliance",
"Substance Abuse, Intravenou... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 1,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 1
} |
9409779 | Alternative splicing of a Caenorhabditis elegans gene produces two novel inhibitory amino acid receptor subunits with identical ligand binding domains but different ion channels. | Two full-length cDNAs, gbr-2A and gbr-2B, encoding inhibitory amino acid receptor subunits have been amplified and cloned from Caenorhabditis elegans mRNA. The 5' 732 bp of the two cDNAs, encoding 237 amino acids, are identical. The 3' 758 bp of the gbr-2B cDNA are present within the 3' untranslated region of the gbr-2... | [
1638,
2586,
28,
30,
439,
1703,
3174,
12631,
1225,
6768,
8740,
12397,
1527,
1027,
37,
451,
452,
15435
] | [
"Adaptor Proteins, Signal Transducing",
"Alternative Splicing",
"Amino Acid Sequence",
"Animals",
"Base Sequence",
"Binding Sites",
"Caenorhabditis elegans",
"Chloride Channels",
"Cloning, Molecular",
"DNA, Helminth",
"GRB2 Adaptor Protein",
"Genes, Helminth",
"Ion Channels",
"Ligands",
... | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
1319624 | A new bluetongue virus serotype isolated in Kenya. | An apparently new strain of bluetongue virus was first isolated in Kenya in 1965 and since, has been obtained on 7 further occasions from diseased sheep during clinical outbreaks of disease. It proved to be serologically different from the 16 bluetongue virus strains then held at this laboratory. The virus was modified... | [
30,
1224,
7106,
7107,
2216,
2065,
766,
7108,
1046,
2218,
1566,
7109,
7110
] | [
"Animals",
"Antibodies, Viral",
"Bluetongue",
"Bluetongue virus",
"Disease Outbreaks",
"Fluorescent Antibody Technique",
"Immune Sera",
"Kenya",
"Neutralization Tests",
"Serotyping",
"Sheep",
"Vaccines, Attenuated",
"Viral Vaccines"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 1,
"Z": 1
} |
1443636 | Spectrofluorimetric determination of tetracycline and anhydrotetracycline in serum and urine. | A spectrofluorimetric method, involving alkaline degradation and formation of a magnesium complex, is described for the determination of tetracycline (TC) and anhydrotetracycline (ATC) in their mixed solution. Tetracycline is degraded and determined in alkaline solution. This treatment of ATC produces almost no fluores... | [
3,
1873,
4576,
7534
] | [
"Humans",
"Spectrometry, Fluorescence",
"Tetracycline",
"Tetracyclines"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
8545382 | [Treatment of rheumatoid psoriasis with bromocriptine]. | Non-steroid anti-inflammatory drugs and/or gold salts were unsuccessful alone in providing symptom relief in three men with rheumatoid psoriasis. All three were treated with bromocriptine (5 mg/d in 2 doses) after verification of normal baseline and protirelin-stimulation prolactin levels. There was a beneficial effect... | [
9,
6327,
14400,
1675,
3,
35,
160,
483
] | [
"Adult",
"Arthritis, Psoriatic",
"Bromocriptine",
"Hormone Antagonists",
"Humans",
"Male",
"Middle Aged",
"Quality of Life"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 1,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
15815210 | Endobiliary stents for palliation in patients with malignant obstructive jaundice. | BACKGROUND: Endobiliary drainage for malignant obstructive jaundice presents a viable palliative alternative. Its role and efficacy depend on factors related to the stent, procedure, and patient.GOALS: To review the evidence in the literature in which settings plastic or metal stents are cost-effective, and whether adj... | [
5383,
918,
2,
163,
3,
6855,
35,
920,
10025,
598,
8085,
177,
417,
233,
143,
144
] | [
"Bile Ducts",
"Cost-Benefit Analysis",
"Female",
"Follow-Up Studies",
"Humans",
"Jaundice, Obstructive",
"Male",
"Palliative Care",
"Prosthesis Implantation",
"Retrospective Studies",
"Review Literature as Topic",
"Risk Factors",
"Sex Factors",
"Stents",
"Survival Rate",
"Treatment Out... | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 1,
"Z": 0
} |
27687231 | Molecular epidemiology of norovirus in asymptomatic food handlers in Busan, Korea, and emergence of genotype GII.17. | The molecular epidemiology of norovirus infections was studied in food handlers without any symptoms from January to December 2015 in Busan city, Korea. A total of 2,174 fecal specimens from asymptomatic food handlers were analyzed, and 2.3% (49/2,174) were norovirus-positive. Fourteen of 335 samples (4.2%) were positi... | [
17295,
10084,
2216,
157,
2,
6494,
6290,
220,
3,
35,
10085,
1035,
1037,
597,
1336
] | [
"Asymptomatic Infections",
"Caliciviridae Infections",
"Disease Outbreaks",
"Feces",
"Female",
"Food Handling",
"Gastroenteritis",
"Genotype",
"Humans",
"Male",
"Norovirus",
"Phylogeny",
"RNA, Viral",
"Republic of Korea",
"Sequence Analysis, DNA"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 1,
"M": 0,
"N": 1,
"Z": 1
} |
30734450 | Pollination ecology of the Neotropical gesneriad Gloxinia perennis: chemical composition and temporal fluctuation of floral perfume. | Although common among orchids, pollination by perfume-gathering male euglossine bees is quite rare in other Neotropical families. In Gesneriaceae, for example, it is reported in two genera only, Drymonia and Gloxinia. Flowers of G. perennis are known to emit perfume, thereby attracting male euglossine bees as pollinato... | [
30,
4467,
6623,
7295,
14760,
7144,
3175,
6791,
131
] | [
"Animals",
"Bees",
"Ecology",
"Flowers",
"Lamiales",
"Peru",
"Pheromones",
"Pollination",
"Time Factors"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 1,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 1
} |
2846779 | Antigenic variation in alkaline deoxyribonuclease induced by three different strains of Epstein-Barr virus. | To determine whether biological and/or biochemical variants exist between strains of Epstein-Barr virus (EBV), we superinfected Raji cells with the nontransforming lytic strain of EBV (HR-1), and two isolates that both transform B-lymphocytes and superinfect Raji cells, B95-8, and NPC-EBV. The superinfected cells were ... | [
8964,
1062,
657,
11866,
777,
2788,
3,
1046
] | [
"Antigenic Variation",
"Antigens, Viral",
"Cell Line",
"Deoxyribonucleases",
"Electrophoresis, Polyacrylamide Gel",
"Herpesvirus 4, Human",
"Humans",
"Neutralization Tests"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
2266226 | Social problem-solving in depressed, conduct-disordered, and normal adolescents. | Although past theory and research implicate social problem-solving deficits in both depression and aggressive disorders, research examining carefully diagnosed groups of adolescent depressed and conduct-disordered groups had not previously been conducted. In the current study three groups of adolescents (major depressi... | [
204,
4808,
2026,
2,
3,
35,
1700,
1167,
1604,
1582
] | [
"Adolescent",
"Aggression",
"Depressive Disorder",
"Female",
"Humans",
"Male",
"Personality Development",
"Personality Inventory",
"Problem Solving",
"Social Behavior"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 0,
"F": 1,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
17581682 | Effect of 5-HT1B receptor agonists injected into the prefrontal cortex on maternal aggression in rats. | Serotonin (5-HT1B) receptors play an essential role in the inhibition of aggressive behavior in rodents. CP-94,253, a 5-HT1B receptor agonist, can reduce aggression in male mice when administered directly into the ventro-orbitofrontal (VO) prefrontal cortex (PFC). The objective of the current study was to assess the ef... | [
4808,
30,
1104,
2,
35,
5145,
4197,
1603,
139,
4650,
43,
245,
14848,
6941
] | [
"Aggression",
"Animals",
"Behavior, Animal",
"Female",
"Male",
"Maternal Behavior",
"Microinjections",
"Prefrontal Cortex",
"Pyridines",
"Pyrroles",
"Rats",
"Rats, Wistar",
"Receptor, Serotonin, 5-HT1B",
"Serotonin Receptor Agonists"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 1,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
21902658 | The effect of chronic co-administration of morphine and verapamil on isoproterenol-induced heart injury. | OBJECTIVE: Long-term co-administration of morphine and calcium channel antagonists (CCAs) is likely in some clinical conditions. Reciprocal interactions during chronic concomitant use of these agents are confirmed in central nervous system studies. However, there is little information regarding their chronic combinatio... | [
30,
2503,
300,
3418,
1234,
15205,
3360,
35,
2162,
1980,
5502,
43,
245,
7571,
5941
] | [
"Animals",
"Calcium Channel Blockers",
"Cardiotonic Agents",
"Drug Synergism",
"Heart",
"Heart Injuries",
"Isoproterenol",
"Male",
"Morphine",
"Myocardium",
"Narcotics",
"Rats",
"Rats, Wistar",
"Troponin I",
"Verapamil"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
21863011 | Anatomically modern Carboniferous harvestmen demonstrate early cladogenesis and stasis in Opiliones. | Harvestmen, the third most-diverse arachnid order, are an ancient group found on all continental landmasses, except Antarctica. However, a terrestrial mode of life and leathery, poorly mineralized exoskeleton makes preservation unlikely, and their fossil record is limited. The few Palaeozoic species discovered to date ... | [
30,
13003,
2132,
4719,
4915,
1035
] | [
"Animals",
"Arachnida",
"Biological Evolution",
"Fossils",
"Genetic Speciation",
"Phylogeny"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 0,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 1,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
2827827 | Inhibition by quinine of endothelium-dependent relaxation of rabbit aortic strips. | 1 The effects of quinine sulphate, tetramethylammonium chloride (TMA) and tetraethylammonium chloride (TEA) (all blockers of the Ca2+-activated K+ channels) on the relaxations induced by acetylcholine (ACh), calcium ionophore A23187 and sodium nitrite were studied in helical strips of rabbit aorta. 2 The strips were co... | [
17610,
7351,
30,
3439,
3088,
3089,
1739,
3090,
3234,
2,
34,
35,
5868,
2665,
67,
4409,
772,
13905,
15974
] | [
"4-Aminopyridine",
"Aminopyridines",
"Animals",
"Aorta, Thoracic",
"Barium",
"Barium Compounds",
"Calcimycin",
"Chlorides",
"Endothelium, Vascular",
"Female",
"In Vitro Techniques",
"Male",
"Muscle Relaxation",
"Muscle, Smooth, Vascular",
"Quaternary Ammonium Compounds",
"Quinine",
"... | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
25308571 | Shared decision making for hydroxyurea treatment initiation in children with sickle cell anemia. | Clinical trials have demonstrated hydroxyurea's efficacy in improving health outcomes for children with sickle cell anemia (SCA) who have medical complications. New NHLBI clinical guidelines will recommend offering hydroxyurea to young patients regardless of clinical severity. Shared decision making may be an effective... | [
6318,
6319,
104,
6320,
879,
3,
5047,
4446,
3626
] | [
"Anemia, Sickle Cell",
"Antisickling Agents",
"Child",
"Clinical Decision-Making",
"Decision Making",
"Humans",
"Hydroxyurea",
"Parents",
"Physician-Patient Relations"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 1,
"G": 0,
"H": 0,
"I": 1,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
2741259 | [Long-term experiences following extracorporeal shockwave lithotripsy in patients with urinary calculi]. | A report is given on the experience we have had over a period of up to 7 years following ESWL treatment in urinary stone patients. 131I-hippuran clearance studies were conducted on 19 patients prior to and 6.6 years subsequent to ESWL. There was no evidence of any degree of deterioration in total renal function or of a... | [
9,
2,
163,
3,
19601,
6407,
21821,
3703,
35,
160,
1237,
10682,
2982
] | [
"Adult",
"Female",
"Follow-Up Studies",
"Humans",
"Iodohippuric Acid",
"Kidney Calculi",
"Kidney Calices",
"Lithotripsy",
"Male",
"Middle Aged",
"Recurrence",
"Ureteral Calculi",
"Urodynamics"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
10853218 | Target-controlled intravenous anaesthesia with bispectral index monitoring for thoracotomy in a patient with severely impaired left ventricular function. | The anaesthetic management of an elderly patient with severely impaired left ventricular function undergoing thoracotomy and lobectomy is described. Total intravenous anaesthesia (TIVA) with remifentanil and target-controlled infusion of propofol titrated according to the bispectral index (BIS) was used, with thoracic ... | [
133,
12884,
12885,
792,
793,
721,
11497,
487,
523,
3,
138,
3677,
159,
35,
2647,
363,
6585,
801,
12886,
4854,
2558,
12887,
8410
] | [
"Aged",
"Analgesia, Epidural",
"Anesthesia Recovery Period",
"Anesthesia, Intravenous",
"Anesthetics, Intravenous",
"Carcinoma, Squamous Cell",
"Cardiomyopathy, Dilated",
"Electroencephalography",
"Hemodynamics",
"Humans",
"Infusions, Intravenous",
"Intubation, Intratracheal",
"Lung Neoplasm... | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 1,
"N": 1,
"Z": 0
} |
18486477 | The lumbar roots and pedicles: a morphometric analysis and anatomical features. | The objective of this study was to conduct a morphometric analysis of the lumbar nerve roots and surrounding structures. In this investigation, the lumbar roots were studied in 14 cadavers (70 lumbar vertebrae). Lumbar pedicle heights and widths were measured at every level of the lumbar vertebrae. The largest mean roo... | [
204,
9,
133,
1471,
2,
3,
2351,
35,
160,
8169
] | [
"Adolescent",
"Adult",
"Aged",
"Cadaver",
"Female",
"Humans",
"Lumbar Vertebrae",
"Male",
"Middle Aged",
"Spinal Nerve Roots"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 0,
"F": 0,
"G": 0,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 0,
"Z": 0
} |
15249581 | Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. | The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the central spindle in mitosis. Here, we describe Borealin, a novel member of the complex. Approximately half of Aurora B in mitotic cells is complexed with INCENP, Borealin, and Survivin; and Bo... | [
28,
30,
1703,
1296,
1503,
4565,
8999,
3,
2442,
1531,
3249,
666,
2452,
584,
505,
2155,
9573,
2443
] | [
"Amino Acid Sequence",
"Animals",
"Binding Sites",
"Cell Cycle Proteins",
"Cell Division",
"Chromosomal Proteins, Non-Histone",
"Chromosomes",
"Humans",
"Inhibitor of Apoptosis Proteins",
"Macromolecular Substances",
"Microtubule-Associated Proteins",
"Mutation",
"Neoplasm Proteins",
"Nucl... | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 1,
"M": 0,
"N": 0,
"Z": 0
} |
12870812 | EI-1941-1 and -2, novel interleukin-1beta converting enzyme inhibitors produced by Farrowia sp. E-1941. I. Biochemical characterization of EI-1941-1 and -2. | EI-1941-1 and -2 isolated from the culture broths of Farrowia sp. selectively inhibited the human recombinant ICE activity with IC50 values of 0.086 and 0.006 microM, respectively, without inhibiting elastase and cathepsin B. EI-1941-1 and -2 also inhibited mature interleukin-1beta secretion from THP-1 cells induced by... | [
10349,
1705,
4151,
134,
1969,
8911,
1109,
3,
4389,
4543,
376
] | [
"Cyclohexanones",
"Cysteine",
"Dithiothreitol",
"Dose-Response Relationship, Drug",
"Drug Stability",
"Epoxy Compounds",
"Glutathione",
"Humans",
"Interleukin-1",
"Serpins",
"Viral Proteins"
] | {
"A": 0,
"B": 1,
"C": 0,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
30612202 | Exercise-induced improvements in glucose effectiveness are blunted by a high glycemic diet in adults with prediabetes. | AIMS: Glucose effectiveness (GE) refers to the ability of glucose to influence its own metabolism through insulin-independent mechanisms. Diminished GE is a predictor of progression to type 2 diabetes. Exercise training improves GE, however, little is known about how dietary interventions, such as manipulating the glyc... | [
133,
1778,
3776,
983,
2,
2369,
3422,
12975,
3,
1520,
35,
160,
596,
11705,
144
] | [
"Aged",
"Diabetes Mellitus, Type 2",
"Diet Therapy",
"Exercise Therapy",
"Female",
"Glucose",
"Glucose Tolerance Test",
"Glycemic Index",
"Humans",
"Insulin Resistance",
"Male",
"Middle Aged",
"Obesity",
"Prediabetic State",
"Treatment Outcome"
] | {
"A": 0,
"B": 1,
"C": 1,
"D": 1,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 1,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
7276044 | Surface replacement of the hip with the Tharies system. Two to five-year results. | The two to five-year clinical results of 200 Tharies surface replacements were comparable to those of conventional total hip replacement. The incidence of systemic complications, dislocations, and sepsis was low. There were ten cases of aseptic and one case of septic loosening. Nine minor secondary procedures were requ... | [
204,
9,
133,
2,
163,
3950,
3301,
12945,
3,
3781,
35,
160,
492,
695,
189
] | [
"Adolescent",
"Adult",
"Aged",
"Female",
"Follow-Up Studies",
"Gait",
"Hip Joint",
"Hip Prosthesis",
"Humans",
"Joint Diseases",
"Male",
"Middle Aged",
"Movement",
"Postoperative Complications",
"Radiography"
] | {
"A": 1,
"B": 1,
"C": 1,
"D": 0,
"E": 1,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 1,
"N": 1,
"Z": 0
} |
25369806 | Differentiation of Schwann‑like cells from human umbilical cord blood mesenchymal stem cells in vitro. | The use of artificial nerves for the repair of peripheral nerve defects is restricted by the limited sources of Schwann cells (SCs). Human mesenchymal stem cell (MSC)‑derived Schwann‑like cells are considered an alternative and desirable cell source. The aim of the present study was to establish a method of inducing di... | [
4997,
612,
51,
288,
3076,
3,
618,
10108,
1951,
14678,
8168
] | [
"Adipocytes",
"Cell Differentiation",
"Cells, Cultured",
"Fetal Blood",
"Glial Fibrillary Acidic Protein",
"Humans",
"Mesenchymal Stem Cells",
"Osteocytes",
"Osteogenesis",
"S100 Calcium Binding Protein beta Subunit",
"Schwann Cells"
] | {
"A": 1,
"B": 1,
"C": 0,
"D": 1,
"E": 0,
"F": 0,
"G": 1,
"H": 0,
"I": 0,
"J": 0,
"L": 0,
"M": 0,
"N": 0,
"Z": 0
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.