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23988419 | Outcomes of 447 SCORE® highly congruent mobile-bearing total knee arthroplasties after 5-10 years follow-up. | INTRODUCTION: The goal of mobile-bearing total knee arthroplasties (TKA) with an anatomical trochlea is to reduce polyethylene wear, the risk of loosening, and patellofemoral complications. Rotating mobile-bearing SCORE(®) TKA was designed according to these principles with standard instrumentation for component placem... | [
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"Aged",
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"Cohort Studies",
"Female",
"Follow-Up Studies",
"France",
"Humans",
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"Middle Aged",
"Pain Measurement",
"Patient Satisfaction",
"Prosthesis Design",
"Prosthesis Failure",
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12502367 | New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization. | A series of benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives were prepared and evaluated to determine the necessary requirements for high affinity on the 5-HT(4) receptors and high selectivity versus other receptors. The compounds were synthesized by substituting the chlorine atom of benzonaphthyridin... | [
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20019817 | Investigating the role of mitochondrial haplogroups in genetic predisposition to meningococcal disease. | BACKGROUND AND AIMS: Meningococcal disease remains one of the most important infectious causes of death in industrialized countries. The highly diverse clinical presentation and prognosis of Neisseria meningitidis infections are the result of complex host genetics and environmental interactions. We investigated whether... | [
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6291158 | [Management of pulmonary metastases from osteosarcomas]. | The management of pulmonary metastases from osteosarcomas rests at present on thoracic surgery combined with chemotherapy. Until the beginning of the seventies chemotherapy proved very disappointing. With adriamycin, methotrexate in high doses followed by folinic acid and, more recently, platinum cis-dichlorodiamine, r... | [
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3652074 | Structure of the serotype f polysaccharide antigen of Streptococcus mutans. | The structure of the serotype f polysaccharide antigen of Streptococcus mutans was determined by methylation analysis, periodate oxidation, and partial methanolysis, and the configuration of the anomeric linkages by 13C-n.m.r. spectroscopy, indicating the trisaccharide repeating unit----3)-alpha-L-Rhap-(1----2)-[alpha-... | [
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12832254 | Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. | OBJECTIVE: This study investigated whether the functional abnormalities in prefrontal systems observed in adult bipolar disorder are manifested in adolescents with this illness.METHOD: Ten adolescents with bipolar disorder and 10 healthy comparison subjects participated in a color-naming Stroop task during event-relate... | [
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27418618 | Description and Impact Evaluation of a Statewide Collaboration to Reduce Preventable Hospital Readmissions. | This article describes how a Medicare-funded Quality Improvement Organization collaborated with a hospital association and multiple cross-continuum partners on a statewide effort to reduce hospital readmissions. Interventions included statewide education on quality improvement strategies and community-specific technica... | [
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25289732 | Endoscopic, transoral, reduction of epiglottic entrapment via wire snare technique. | OBJECTIVE: To describe the use of a wire snare technique for epiglottic entrapment.STUDY DESIGN: Case series.ANIMALS: Eight adult horses.METHODS: Under general anesthesia, a modified mouth gag was placed in the oropharynx. An endoscope was passed through the gag until there was adequate visualization of the entrapped e... | [
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7446019 | Bone marrow cell content and osteoclasts in crista biopsies. | The bone marrow cell content was investigated by counting the percentage of cells in the areas between the trabeculae in crista biopsies. There was a decrease in the percentage of cells in bone marrow in osteoporotic women compared with our normal material. In patients undergoing haemodialysis there was a positive corr... | [
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2424450 | Acetylsalicylic acid antagonizes the bleeding-induced changes in hemoglobin proportions in normal adult rats. | Normal adult Sprague-Dawley rats were made anemic by repeated phlebotomy. Ion-exchange chromatography of anemic blood showed newborn like hemoglobin proportions, involving the same six hemoglobin components as is found when newborn and adult blood are compared. However, acetylsalicylic acid intake during anemia failed ... | [
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4092487 | Repetitive naming and the detection of word retrieval deficits in the beginning reader. | The claim has been advanced that children with severe reading disability are generally deficient in word retrieval compared with normal readers. Support for the claim is based largely on studies of rapid naming of repetitively presented pictured objects or other nameable stimuli, a task which is apparently more sensiti... | [
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18182846 | Overexpression of SOX15 inhibits proliferation of NT2/D1 cells derived from a testicular embryonal cell carcinoma. | SOX (Sry-related HMG box) family proteins, which have an evolutionarily conserved DNA binding domain, have crucial roles in cell differentiation. However, their target genes remain enigmatic. Some members of the SOX family may have roles in regulation of cell proliferation. We established stable NT2/D1 cell lines overe... | [
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"Male",
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16764265 | Texture characterization for joint compression and classification based on human perception in the wavelet domain. | Today's multimedia applications demand sophisticated compression and classification techniques in order to store, transmit, and retrieve audio-visual information efficiently. Over the last decade, perceptually based image compression methods have been gaining importance. These methods take into account the abilities (a... | [
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"Visual Perception"
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6894560 | Three years' experience of sexually transmitted diseases in Seville, Spain. | At present there are no reliable statistics on the relative prevalences of sexually transmitted diseases (STDs) in Spain. In a report of the first three years' experience in an STD diagnostic centre between 1977 and 1979 a total of 879 patients (534 men adn 345 women) were seen. They mainly consisted of university stud... | [
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2537760 | Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4. | Vascular endothelial cells and neutrophils synthesize and release potent vasodilatatory factors, i.e. endothelium-derived relaxing factors (EDRF) and neutrophil-derived relaxing factors (NDRF). One EDRF has been identified as nitric oxide (NO) derived from arginine. We studied the synthesis and release of NO from human... | [
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9278541 | Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. | The PDAPP transgenic mouse overexpresses human amyloid precursor protein V717F (PDAPP minigene) and develops age-related cerebral amyloid-beta protein (Abeta) deposits similar to senile plaques in Alzheimer's disease. We find age-related cortical and limbic Abeta deposition that begins at 8 months and progresses to cov... | [
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8242167 | Alternative barrier technique. | This article offers an alternative barrier technique that not only places the barrier in the dental treatment room, but also places it under the direct supervision and control of the dentist. A known hepatitis B carrier was selected for immediate denture treatment to illustrate and test this proposed barrier technique. | [
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1338047 | Interaction of diltiazem with single L-type calcium channels in guinea-pig ventricular myocytes. | The effects of diltiazem on cardiac L-type calcium channels were studied at the single channel level, using Ba2+ ions as the charge carrier. Patch clamp experiments were performed on enzymatically isolated guinea-pig ventricular myocytes. It was shown in cell-attached configuration on multichannel patches that diltiaze... | [
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23763619 | Characterization of nitrite uptake in Arabidopsis thaliana: evidence for a nitrite-specific transporter. | Nitrite-specific plasma membrane transporters have been described in bacteria, algae and fungi, but there is no evidence of a nitrite-specific plasma membrane transporter in higher plants. We have used 13NO2(-) to characterize nitrite influx into roots of Arabidopsis thaliana. Hydroponically grown Arabidopsis mutants, ... | [
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16928213 | Does co-infection with multiple viruses adversely influence the course and outcome of sporadic acute viral hepatitis in children? | BACKGROUND: This study looked at the frequency of co-infection with multiple hepatotropic viruses and the effect of such infection on the course and outcome of acute sporadic viral hepatitis (AVH) and fulminant hepatic failure (FHF) in children.METHODS: Consecutive children up to 15 years of age presenting with AVH or ... | [
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1583218 | Perceptual organization and schizotypy. | The preattentive visual information processing of hypothetically psychosis-prone college subjects was evaluated using three different paradigms, target detection (n = 57), visual suffix effect (n = 57), and configural superiority effect (n = 68). It was hypothesized that anhedonic subjects would show the same perceptua... | [
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31204287 | Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A. | ATP-driven bacterial AAA+ proteases have been recognized as drug targets. They possess an AAA+ protein (e.g., ClpC), which threads substrate proteins into an associated peptidase (e.g., ClpP). ATPase activity and substrate selection of AAA+ proteins are regulated by adapter proteins that bind to regulatory domains, suc... | [
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23275380 | Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury. | Yap1 is an important regulator of cardiomyocyte proliferation and embryonic heart development, yet the function of endogenous Yap1 in the adult heart remains unknown. We studied the role of Yap1 in maintaining basal cardiac function and in modulating injury after chronic myocardial infarction (MI). Cardiomyocyte-specif... | [
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3317256 | Decreased renal perfusion after correction of experimental coarctation. | Hemodynamical changes in coarctation were studied with an experimental model. Coarctation of the thoracic aorta was induced in seven puppies at the age of 8 wk. After a 7-month follow-up period a corrective operation with a venous patch was performed. Two dogs were lost a few hours after the correction operation. The r... | [
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26118861 | Ecotoxicity of sediments in rivers: Invertebrate community, toxicity bioassays and the toxic unit approach as complementary assessment tools. | The determination of the real toxicity of sediments in aquatic ecosystems is challenging and necessary for an appropriate risk assessment. Different approaches have been developed and applied over the last several decades. Currently, the joint implementation of chemical, ecological and toxicological tools is recommende... | [
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31090483 | Interleukin-37 Inhibits the Imbalance Between T Helper 17 Cells and Regulatory T Cells in Hand, Foot, and Mouth Disease. | The aim of this study was to explore the role of interleukin-37 (IL-37) in imbalance of T helper (Th)17/regulatory T cells (Tregs) in hand, foot, and mouth disease (HFMD). The proportions of CD4+ IL-17A+ Th17 cells and CD4+ CD25+Foxp3+ Tregs in peripheral blood or peripheral blood mononuclear cells (PBMCs) from HFMD pa... | [
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26548979 | Narcissistic vulnerability is a common cause for depression in patients with Gilles de la Tourette syndrome. | The aim of this study was to assess for the first time different dimensions of narcissistic self-regulation in a large cohort of adult patients with Gilles de la Tourette syndrome (GTS) (n=50). From preliminary studies it is suggested that narcissistic personality trait and disorder, respectively, are relatively uncomm... | [
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9117440 | Bacterial lipopolysaccharide binds to CD14 in low-density domains of the monocyte-macrophage plasma membrane. | We report that gram-negative bacterial lipopolysaccharide (LPS) binds to CD14 on lipid-enriched, low-density domains of the human monocyte-macrophage (THP-1 cell) plasma membrane. After brief incubation with [3H]LPS under conditions that prevent its internalization, THP-1 cells were disrupted using a detergent-free met... | [
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24848257 | Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. | Suppression of the host's immune system plays a major role in cancer progression. Tumor signaling of programmed death 1 (PD1) on T cells and expansion of myeloid-derived suppressor cells (MDSCs) are major mechanisms of tumor immune escape. We sought to target these pathways in rhabdomyosarcoma (RMS), the most common so... | [
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7455669 | Mycoplasma pneumonia: failure of erythromycin therapy. | Two cases of mycoplasma pneumonia are described which failed to respond to prolonged treatment with erythromycin. The substitution of oxytetracycline therapy resulted in rapid clinical and radiological resolution. | [
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2506162 | Treatment of idiopathic hepatic lipidosis in cats: 11 cases (1986-1987). | Idiopathic hepatic lipidosis was diagnosed in 11 cats. Cats were treated by delivery of balanced nutrients supplemented with L-carnitine via a surgically placed gastrostomy tube. Feeding through the gastrostomy tube was initiated in the hospital and was continued at home in all cats. The mean duration of gastrostomy tu... | [
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22674657 | Tramadol enhances urethral continence function through µ-opioid receptors in rats. | AIMS: (±)-Tramadol hydrochloride (tramadol) is a widely used analgesic that stimulates the µ-opioid receptor and inhibits the reuptake of serotonin and noradrenalin. Although tramadol is also known to inhibit the micturition reflex in rats, its effects on urethral continence function have not been reported. We therefor... | [
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28295611 | Variation in Networks and Forms of Support for Care-Seeking Across the HIV Care Continuum in the Rural Southeastern United States. | PURPOSE: In spite of progress in understanding the importance of social support for health outcomes in Persons Living with HIV (PLWH), more remains to be known about mechanisms of support most beneficial at each stage of HIV treatment. In this study, we use a qualitative analytic approach to investigate the forms and s... | [
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3919460 | Effect of bacterial products on human ciliary function in vitro. | Ciliary activity protects the respiratory tract against inhaled particles, including bacteria, by transporting them trapped in mucus towards the pharynx. We have studied the effect of bacteria (Haemophilus influenzae, Staphylococcus aureus, and Pseudomonas aeruginosa) on human nasal cilia, measuring their in vitro cili... | [
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17373823 | Flux balance analysis of a genome-scale yeast model constrained by exometabolomic data allows metabolic system identification of genetically different strains. | A systems approach to biology requires a principled approach to pathway identification. In this study, the two nuclear petite yeast mutants K1Deltapet191a and K1Deltapet191ab and their parental industrial strain K1 were cultured in glucose-containing microaerobic chemostats. Exometabolomic profiles were used to infer t... | [
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25494779 | Accurate small and wide angle x-ray scattering profiles from atomic models of proteins and nucleic acids. | A new method is introduced to compute X-ray solution scattering profiles from atomic models of macromolecules. The three-dimensional version of the Reference Interaction Site Model (RISM) from liquid-state statistical mechanics is employed to compute the solvent distribution around the solute, including both water and ... | [
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2820999 | Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. | Biochemical studies in vertebrate olfactory tissue indicate that certain odorants stimulate adenylyl cyclase in a GTP-dependent manner. Additionally, immunochemical and toxin-labeling studies demonstrate the presence of several GTP-binding protein (G-protein) species in vertebrate olfactory epithelium. To identify the ... | [
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22472933 | Association of systemic-onset juvenile idiopathic arthritis and celiac disease - a case report. | INTRODUCTION: In a 28-year period, 5508 patients were followed at our Paediatric Rheumatology Division and 712 (13%) patients had juvenile idiopathic arthritis (JIA) (ILAR criteria). One (0.14%) of them had association with celiac disease (CD), with predominance of gastrointestinal manifestations and this case was desc... | [
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28160852 | Antidiarrhoeal activity of eriosematin E isolated from the roots of Eriosema chinense Vogel. | BACKGROUND: Roots of the plant Eriosema chinense Vogel (Fabaceae) is distributed mainly over the Eastern Himalayan region of India and China. The roots of the plant are used as a vegetable by the people of Northern Australia, China and North East India and are used traditionally by the tribal people of Meghalaya (India... | [
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15668 | Structural changes and fluctuations of proteins. II. Analysis of the denaturation of globular proteins. | The statistical thermodynamic model of protein structure proposed in paper I is developed with special attention to the hydrophobic interaction. Calorimetric measurements of the thermal denaturation of five globular proteins, ribonuclease A, lysozyme, alpha-chymotrypsin, cytochrome c, and myoglobin, are quantitatively ... | [
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23587389 | Revised digestive parameter estimates for the Molly cow model. | The Molly cow model represents nutrient digestion and metabolism based on a mechanistic representation of the key biological elements. Digestive parameters were derived ad hoc from literature observations or were assumed. Preliminary work determined that several of these parameters did not represent the true relationsh... | [
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23342170 | Glycogen synthase kinase 3â promotes osteogenic differentiation of murine adipose-derived stromal cells. | Although the role of glycogen synthase kinase 3â (GSK3â) in osteogenic differentiation of bone marrow-derived mesenchymal stromal cells (BMSCs) is well-characterized as a negative regulator of â-catenin, its effect on osteogenesis of adipose-derived stromal cells (ADSCs) is poorly understood. Here, we show that GSK3â p... | [
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16242858 | Effects of maternal separation, early handling, and standard facility rearing on orienting and impulsive behavior of adolescent rats. | Effects of maternal separation in rats have been extensively investigated, but no studies have examined its effects in rat adolescence. We examined the effects of neonatal infant-mother separation (MS) for 6h/day and early handling (EH) for 10 days during the first 2 weeks of life by comparing MS and EH groups to stand... | [
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1262389 | Action of dichlorobenzimidazole riboside on RNA synthesis in L-929 and HeLa cells. | 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) inhibits RNA synthesis in L-929 cells (mouse fibroblast line) and HeLa cells (human epitheloid carcinoma line) within 2 min of addition of the compound to the medium. By removing DRB from the medium, the inhibition is promptly and completely reversed after treatmen... | [
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30776144 | Possible association of HMOX1 and NQO1 polymorphisms with anti-tuberculosis drug-induced liver injury: A matched case-control study. | WHAT IS KNOWN AND OBJECTIVE: Reactive metabolites from anti-tuberculosis (anti-TB) drugs can result in abnormal accumulation of reactive oxygen species (ROS), which plays an important role in anti-TB drug-induced liver injury (ATLI). Liver cells could keep the production of ROS in balance by antioxidant activities. The... | [
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26114551 | The Role of MDR-Acinetobacter baumannii in Orthopedic Surgical Site Infections. | BACKGROUND: Gram-positive microorganisms were the main causative organisms of orthopedic surgical site infections (SSI); however the rising incidence of multiple drug resistant Acinetobacter baumannii (MDR-AB) infections in orthopedic operations causes a great concern because of their limited array of therapeutic optio... | [
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19546282 | Sepsis: a need for prehospital intervention? | Prehospital staff have made a significant contribution in recent years to improving care for patients with acute coronary syndrome, multiple trauma and stroke. There is, however, another group of patients that is not currently being targeted, with a similar time-critical condition. This group of patients is those with ... | [
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"Communication",
"Critical Illness",
"Emergency Medical Services",
"Emergency Treatment",
"Fluid Therapy",
"Humans",
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"Oxygen",
"Sepsis"
] | {
"A": 0,
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"C": 1,
"D": 1,
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"N": 1,
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} |
29140639 | Determining the Effectiveness of Mirrors and Camera Systems in Monitoring the Rearward Visibility of Self-Propelled Agricultural Machinery. | This study concerned the ability of operators of tractors and other self-propelled agricultural machinery to visually recognize objects and/or hazards within close proximity to the rear of those machines and/or any implements in tow, especially when backing up. It was hypothesized that the data collected would identify... | [
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88,
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641,
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2828
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"Equipment Design",
"Humans",
"Male",
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"Visual Perception"
] | {
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"N": 1,
"Z": 0
} |
24589746 | A mortality study of workers exposed to insoluble forms of beryllium. | This study investigated lung cancer and other diseases related to insoluble beryllium compounds. A cohort of 4950 workers from four US insoluble beryllium manufacturing facilities were followed through 2009. Expected deaths were calculated using local and national rates. On the basis of local rates, all-cause mortality... | [
17858,
10164,
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1812,
4041,
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3,
35,
92,
2765,
132,
4947
] | [
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"Beryllium",
"Cause of Death",
"Cohort Studies",
"Employment",
"Female",
"Humans",
"Male",
"Occupational Exposure",
"Respiratory Tract Diseases",
"United States",
"Uterine Neoplasms"
] | {
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} |
22120715 | Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion. | Our understanding of key epigenetic regulators involved in specific biological processes and cancers is still incomplete, despite great progress in genome-wide studies of the epigenome. Here, we carried out a systematic, genome-wide analysis of the functional significance of 615 epigenetic proteins in prostate cancer (... | [
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18444019 | Associations between psychological demands, decision latitude, and job strain with smoking in female hotel room cleaners in Las Vegas. | BACKGROUND: Little is known of the impact of the work environment on smoking among women holding low-paid jobs in the service sector.PURPOSE: To study the associations between the components of the demand-control model with smoking in hotel room cleaners.METHODS: We conducted a survey on work and health among 776 femal... | [
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"... | {
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7069833 | Preliminary observations on the results of combined 125iodine seed implantation and external irradiation for carcinoma of the prostate. | Fifty-seven patients with localized carcinoma of the prostate were treated with pelvic lymphadenectomy and a reduced 125iodine implant dosage, supplemented by a moderate dose of external beam radiotherapy to the whole pelvis delivered 4 to 6 weeks later. The incidence of pelvic nodal metastases was 28 per cent and the ... | [
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30038097 | Efficacy of the visual evoked potential monitoring in endoscopic transnasal transsphenoidal surgery as a real-time visual function. | Background: Visual evoked potential (VEP) is used as a means of intraoperative visual function monitoring. It remains unclear, however, whether intraoperative VEP monitoring is a means of real-time visual function monitoring that has satisfactory effectiveness and sensitivity. To evaluate this, the relationships betwee... | [
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} |
2924785 | Aneurysm of the left anterior descending coronary artery after chest trauma. | A 28-year old man developed transmural anterior wall myocardial infarction after a car accident despite the absence of external signs of chest trauma. Coronary angiography one month after the accident demonstrated an aneurysm of the left anterior descending artery. Angiography five and eleven months afterwards showed a... | [
9,
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] | [
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} |
17121025 | [Clinical features and epidemiological survey of perianal warts in 72 males]. | OBJECTIVE: To investigate the clinical features and epidemiological data of 72 cases of male perianal warts.METHODS: Seventy-two cases of perianal warts in our clinic dated from June, 2004 to April, 2006 were enrolled in the study, whose clinical information and epidemiological data were collected and analyzed.RESULTS:... | [
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"Adult",
"Anus Diseases",
"Condylomata Acuminata",
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} |
29859591 | Fatal choking in infants and children treated in a pediatric intensive care unit: A 7- year experience. | INTRODUCTION: Foreign bodies aspiration can lead to significant morbidity, few have examined in detail the deaths resulting from foreign bodies aspiration.METHODS: We conducted a review of children who presented to the pediatric intensive care unit of a university hospital due to fatal foreign bodies aspiration during ... | [
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105,
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5369,
7292,
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"Airway Obstruction",
"Asphyxia",
"Child",
"Child, Preschool",
"Female",
"Food",
"Foreign Bodies",
"Humans",
"Infant",
"Intensive Care Units, Pediatric",
"Male",
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] | {
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} |
30352989 | A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the Gallbladder. | BACKGROUND Granulocytic sarcoma, or 'chloroma,' due to extramedullary acute myeloid leukemia (AML) or due to acute myelomonocytic leukemia (AML M5), is rare and is associated with a poor prognosis. This report is of a case of granulocytic sarcoma of the gallbladder and describes the approach to diagnosis and treatment.... | [
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17267,
15004
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"Aged",
"Diagnosis, Differential",
"Female",
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"Leukemia, Myelomonocytic, Acute",
"Sarcoma, Myeloid"
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} |
18459087 | Anti-CD40L monoclonal antibody treatment induces long-term, tissue-specific, immunologic hyporesponsiveness to peripheral nerve allografts. | The CD40/CD40L costimulatory pathway plays a crucial role in allograft rejection. The purpose of this study was to determine the effectiveness of anti-CD40L monoclonal antibody (mAb) treatment as a method to induce long-term, tissue-specific, immunologic hyporesponsiveness to peripheral nerve allografts. Sciatic nerve ... | [
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"Antibodies, Monoclonal",
"CD40 Ligand",
"Cytokines",
"Graft Rejection",
"Graft Survival",
"Immunoglobulin G",
"Immunoglobulin M",
"Injections, Intraperitoneal",
"Mice",
"Mice, Inbred BALB C",
"Mice, Inbred C57BL",
"Sciatic Nerve",
"Transplantation, Homologous"
] | {
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32325594 | Removal of cyanobacteria and control of algal organic matter by simultaneous oxidation and coagulation - comparing the H2 | Cyanobacterial blooms in drinking water are worldwide concern. It is known that pre-oxidation enhanced coagulation can be more efficient at removing algae than traditional coagulation. However, its application is hindered by high oxidant/coagulant consumption and the resultant potential health risk, in the form of alga... | [
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953,
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] | [
"Cyanobacteria",
"Ferric Compounds",
"Ferrous Compounds",
"Hydrogen Peroxide",
"Microcystis",
"Oxidation-Reduction",
"Water Purification"
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} |
9529997 | Microbial hazard of salted OM El-Kholoul (wedge shell Donax trunculus). | Sixty samples of salted OM El-Kholoul were collected from different localities in Giza, Alexandria and Ismailia. The samples were examined organoleptically and bacteriological examination of samples were performed for enumeration of aerobic, Enterobacteriaceae, Staph. aureus, Enterococci counts as well as isolation and... | [
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"Citrus",
"Enterobacteriaceae",
"Mollusca",
"Shellfish",
"Sodium Chloride, Dietary",
"Vibrio parahaemolyticus"
] | {
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} |
1360516 | Microsomal formation of N-benzyl-4-hydroxymethylaniline from N-benzyl-4-methylaniline. | The in-vitro metabolism of N-benzyl-4-methylaniline was re-examined using male hamster and rabbit hepatic microsomes; both species generated N-benzyl-4-hydroxymethylaniline, confirmed by TLC and HPLC, comparison with authentic compound. Further confirmation of the formation of this metabolite was achieved by use of a r... | [
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} |
8555116 | Distress and symptoms of posttraumatic stress disorder in abused women. | Emotional distress and symptoms of posttraumatic stress disorder (PTSD) were examined among women in psychologically abusive relationships. Women (N = 93) were divided into three groups (none, moderate, severe) according to scores on the violence subscale of the Severity of Violence Against Women Scales (Marshall, 1992... | [
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} |
15916762 | Cortical neurogenesis enhanced by chronic perinatal hypoxia. | Most regions of the mature mammalian brain, including the cerebral cortex, appear to be unable to support the genesis of new neurons. Here, we report that a low level of neurogenesis occurs in the cerebral cortex of the infant mouse brain and is enhanced by chronic perinatal hypoxia. When mice were reared in a low-oxyg... | [
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27799156 | Ataxia telangiectasia: presentation and diagnostic delay. | BACKGROUND AND AIMS: Ataxia telangiectasia (A-T) is a rare progressive, multisystem genetic disease. Families of children with ultra-rare diseases often experience significant diagnostic delays. We reviewed the diagnostic process for A-T in order to identify causes of delay in an attempt to facilitate earlier identific... | [
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} |
1059653 | Short-term stress-relaxation behavior of nonmetallic restoratives. | The rheological behavior of five nonmetallic dental materials was studied. Short-term stress relaxation was found to be strongly dependent on time and temperature. Relaxation behavior of the test materials conformed well to simple mathematical models. | [
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9818,
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} |
12857054 | Idiopathic myelofibrosis with refractory massive ascites. | A 55-year-old woman presented with massive refractory ascites in the course of idiopathic myelofibrosis. The ascites was exudative, and a cytological examination revealed granulocytes of varying maturity, erythroblasts, and megakaryocytes with trisomy 8. The ascites was assumed to have developed from peritoneal extrame... | [
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14505920 | Identification of mimotopes by screening of a bacterially displayed random peptide library and its use in eliciting an immune response to native HBV-preS. | Bacterially-displayed peptide libraries have been widely used as an alternative to phage-displayed peptide libraries in screening epitopes or mimotopes of antibodies. Using a protective monoclonal antibody (mAb) 3B9 against hepatitis B virus (HBV) preS protein as target, mimotopes were successfully screened from a FliT... | [
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1374244 | Heterogeneity of 3'untranslated region of bovine acidic FGF transcripts. | A bovine aFGF genomic clone (14.2 Kb) has been isolated and characterized. This clone contains exons 2 and 3 interrupted by 6.7 Kb long intron. Exon 3 contains part of the coding region and the 3' untranslated region (3'UTR). Two overlapping cDNA clones specific for this 3'UTR have been isolated from bovine retina cDNA... | [
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22586267 | The AMPK â2 subunit is required for energy homeostasis during metabolic stress. | AMP activated protein kinase (AMPK) plays a key role in the regulatory network responsible for maintaining systemic energy homeostasis during exercise or nutrient deprivation. To understand the function of the regulatory â2 subunit of AMPK in systemic energy metabolism, we characterized â2 subunit-deficient mice. Using... | [
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21214291 | High energy shock waves and 5-aminolevulinic for sonodynamic therapy: effects in a syngeneic model of colon cancer. | The cytotoxic effect of the natural porphyrin precursor 5-aminolevulinic acid (ALA) exposed to high energy shock waves (HESW) was investigated in vitro on DHD/K12/TRb rat colon cancer cells and in vivo on a syngeneic colon cancer model. In vitro, viable cell growth was determined by trypan blue exclusion assay and cell... | [
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"High-Energy Shock Waves",
"In Situ Nick-End Labeling",
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8221493 | Suicides on Ontario farms. | PURPOSE: To describe the epidemiology of suicides on Ontario farms from 1980-1989, and the ecological relationship between economic strain and farm suicide risk.METHOD: Farm suicides were identified using a computer-assisted search of vital records. Distributions of farm suicides were examined by several demographic va... | [
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21477879 | Texture analysis of poly-adenylated mRNA staining following global brain ischemia and reperfusion. | Texture analysis provides a means to quantify complex changes in microscope images. We previously showed that cytoplasmic poly-adenylated mRNAs form mRNA granules in post-ischemic neurons and that these granules correlated with protein synthesis inhibition and hence cell death. Here we utilized the texture analysis sof... | [
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16151826 | Black thyroid: report of an autopsy case. | A distinctive but very rare side effect of exposure to minocycline is black pigmentation of the thyroid gland. Until 2002, not more than 30 cases of black thyroid had been reported in the English literature. We report on a 24-year-old woman with known antemortem ingestion of minocycline. The woman suffered from a depre... | [
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11533048 | Human glutathione transferase P1-1 and nitric oxide carriers; a new role for an old enzyme. | S-Nitrosoglutathione and the dinitrosyl-diglutathionyl iron complex are involved in the storage and transport of NO in biological systems. Their interactions with the human glutathione transferase P1-1 may reveal an additional physiological role for this enzyme. In the absence of GSH, S-nitrosoglutathione causes rapid ... | [
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21189315 | The effect of acculturation on frailty among older Mexican Americans. | OBJECTIVE: To determine the effect of acculturation on becoming frail and prefrail over a 10-year period among older Mexican Americans.METHOD: A nationally representative sample of 2,049 Mexican Americans aged 67 to 108 was analyzed. Adjusted for sociodemographics and health, longitudinal multinomial mixed models exami... | [
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11313496 | astray, a zebrafish roundabout homolog required for retinal axon guidance. | As growing retinotectal axons navigate from the eye to the tectum, they sense guidance molecules distributed along the optic pathway. Mutations in the zebrafish astray gene severely disrupt retinal axon guidance, causing anterior-posterior pathfinding defects, excessive midline crossing, and defasciculation of the reti... | [
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11050131 | Parallel instabilities of long-term potentiation, place cells, and learning caused by decreased protein kinase A activity. | To further elucidate the links among synaptic plasticity, hippocampal place cells, and spatial memory, place cells were recorded from wild-type mice and transgenic "R(AB)" mice with reduced forebrain protein kinase A (PKA) activity after introduction into a novel environment. Place cells in both strains were similar du... | [
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27483972 | HEALTHCARE FORECASTING IN THE UNITED ARAB EMIRATES (UAE). | This study has been designed to address the issue of the forecasting of the healthcare needs of the United Arab Emirate (UAE) from 1974 to 2011. This includes predicting the health system's need for hospitals and hospital beds, as well as the public health manpower (example, physicians, nurses) requirements. The analys... | [
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1880365 | Tendon excursion and dehiscence during early controlled mobilization after flexor tendon repair in zone II: an x-ray stereophotogrammetric analysis. | The effect of different methods on early controlled mobilization of the flexor profundus tendon regarding tendon excursion and dehiscence was examined during treatment of 20 tendons in 18 patients. An application of radiographic stereophotogrammetric analysis on movements of tendon tissue was developed and the tendons ... | [
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6258364 | Energy metabolism of the peritoneal membrane in silica-induced peritonitis. A biochemical and enzyme histochemical study. | Oxygen and glucose consumption and lactate production of the peritoneal membrane and intra-abdominal adhesions were measured in rats after a single intra-peritoneal colloidal silica injection. Enzyme histochemical studies were made of lactate dehydrogenase, succinate dehydrogenase, NADH2-diaphorase, NADPH2-diaphorase, ... | [
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6183418 | Role of parainfluenza virus-specific IgE in pathogenesis of croup and wheezing subsequent to infection. | In order to determine the role of parainfluenza virus-specific IgE antibody production and release of histamine in the pathogenesis of lower respiratory disease caused by parainfluenza virus infection, we studied 84 infants and children at the time of parainfluenza virus infection. Parainfluenza virus-IgE antibody was ... | [
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24013259 | Choroidal thickness measurement in children using optical coherence tomography. | PURPOSE: To measure choroidal thickness (CT) in children of various ages by using spectral optical coherence tomography with enhanced depth imaging and to investigate the association between subfoveal CT and ocular axial length, age, gender, weight, and height in children.METHODS: Healthy children were prospectively in... | [
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14632796 | Guidelines for the management of pemphigus vulgaris. | These guidelines for management of pemphigus vulgaris have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief over... | [
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12622,
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10389461 | [Feminization of the medical profession]. | Although we can observe a real change in the participation of women in the medical profession, we must ask ourselves what feminisation means. Does it refer to the number of women, or to an eventual change in the content of the profession due to the fact that women are more oriented toward caring, empathy, relationships... | [
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24777807 | Curcumin prevents cerebral ischemia reperfusion injury via increase of mitochondrial biogenesis. | Curcumin is known to have neuroprotective properties in cerebral ischemia reperfusion (I/R) injury. However, the underlying molecular mechanisms remain largely unknown. Recently, emerging evidences suggested that increased mitochondrial biogenesis enabled preventing I/R injury. Here, we sought to determinate whether cu... | [
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14570604 | Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma. | OBJECTIVE: To investigate the antitumor effects of intrasplenically transplanted interleukin-18 (IL-18) gene-modified hepatocytes on murine implanted liver carcinoma.METHODS: Embryonic murine hepatocyte cell line (BNL-CL2) was transfected with a recombinant adenovirus encoding IL-18 and used as delivery cells for IL-18... | [
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23925550 | Real-time monitoring of electrochemical controlled protein adsorption by a plasmonic nanowire based sensor. | A plasmonic sensor composed of a vertically aligned gold nanowire array was fabricated and employed for the optical detection of protein adsorption induced by an electric field. | [
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23824967 | Overriding parents' medical decisions for their children: a systematic review of normative literature. | This paper reviews the ethical literature on conflicts between health professionals and parents about medical decision-making for children. We present the results of a systematic review which addressed the question 'when health professionals and parents disagree about the appropriate course of medical treatment for a c... | [
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3801344 | The prevalence and perceived aetiology of male sexual problems in a non-clinical sample. | One hundred and nine men (38 per cent single, 48 per cent married) participated in a survey of the prevalence of erectile and ejaculatory difficulty in a non-clinical sample. Perceived aetiology of erectile difficulty was also investigated. Twenty-three per cent of the sample were currently experiencing sexual problems... | [
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12638805 | Upper gastrointestinal findings in diabetic outpatients at Kenyatta National Hospital, Nairobi. | OBJECTIVE: To determine the prevalence of H. pylori and the associated upper gastrointestinal endoscopic lesions in diabetic outpatients with dyspepsia.DESIGN: Cross-sectional study.SETTING: Kenyatta National Hospital (KNH), Nairobi, Kenya.SUBJECTS: Adult diabetic outpatients with dyspepsia attending the KNH diabetic c... | [
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27597979 | Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration. | To determine the effectiveness of hemoglobin A1c (HbA1c) ? 6.5% in diagnosing diabetes compared to fasting plasma glucose (FPG) ? 126 mg/dL and 2-hour plasma glucose (2hPG) ? 200 mg/dL in a previously undiagnosed diabetic cohort, we included 5,764 adult subjects without established diabetes for whom HbA1c, FPG, 2hPG, a... | [
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17569719 | Unilateral syphilitic perioptic neuritis in a patient coinfected with human immunodeficiency virus type 1. | Perioptic neuritis caused by secondary syphilis is a rare ophthalmic manifestation in the HIV-infected host. Early diagnosis and treatment of this condition is required to prevent further visual damage. We report a case of unilateral syphilitic perioptic neuritis in a patient coinfected with HIV-1. | [
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8114248 | Acute myeloid leukemia-FAB classification and its correlation with clinico-haematological features. | The French-American and British (FAB) classification of 62 consecutive cases of acute myeloid leukemia was undertaken. AML-M2 was the commonest FAB type (32.26%), followed by M1 and M4 (22.58% each), M5 (8.6%) and M6 and M7 (1.61% each), respectively. One of the patients was diagnosed as AML-MO (not a FAB type). The me... | [
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"Humans",
"Infant",
"Leukemia, Myeloid",
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"United Kingdom",
"United States"
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17009248 | Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis. | OBJECTIVE: : Rheumatoid arthritis (RA) is characterized by hyperplasia of the synovial lining, inflammation, and destruction of cartilage and bone. Since there are only a few detectable cells undergoing apoptosis in the joint, it is possible that a defect in apoptosis may contribute to synovial hyperplasia. This study ... | [
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"Apoptosis Regulatory Proteins",
"Arthritis, Rheumatoid",
"Bcl-2-Like Protein 11",
"Disease Models, Animal",
"Gene Expression Regulation",
"Interleukin-1beta",
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"Myeloid Cell Leukemia Sequence 1 Protein",
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8550466 | Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species. | The surface-exposed lipids of Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium kansasii, Mycobacterium gastri, Mycobacterium smegmatis, and Mycobacterium aurum were isolated by gentle mechanical treatment of cells with glass beads. Analysis of the exposed lipids demonstrated a selective location of classe... | [
6594,
1970,
6288,
1597,
1722
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"Bacterial Capsules",
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"Mycobacterium tuberculosis",
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1761127 | Strategies for developing a family support group. | Various interventions may be used by nurses to provide social support to critical care families. Nurses may support family members in one-to-one relationships, or by facilitating the development of supportive relationships in the group setting. The steps described here are fundamental in developing a support group for ... | [
637,
4629,
1256,
6972,
16976,
3,
7490,
14052,
5690,
498
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"Anxiety",
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"Humans",
"Nursing Diagnosis",
"Self-Help Groups",
"Social Isolation",
"Social Support"
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} |
23688950 | The effect of cocaine on rotarod performance in male C57BL/6J mice. | There is surprisingly little research examining the effect of cocaine on motor learning. Given that changes in motor activity can confound behavioral assays of learning and memory a direct assessment of cocaine on motor learning seems warranted. The present study was conducted to examine the effect of cocaine on motor ... | [
468,
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1575,
1023,
134,
2931,
35,
36,
447,
2370,
3188,
5406,
1110
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"Animals",
"Central Nervous System Stimulants",
"Cocaine",
"Dose-Response Relationship, Drug",
"Learning",
"Male",
"Mice",
"Mice, Inbred C57BL",
"Motor Activity",
"Postural Balance",
"Psychomotor Performance",
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] | {
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} |
663187 | Computed tomographic evaluation of traumatic spinal injuries. | A full radiological evaluation of patients who sustained traumatic injuries to the spine may be difficult to obtain due to the danger associated with manipulation. Computed tomography offers a new modality for simple and accurate evaluation; valuable information may be gained without the use of invasive methods. | [
3,
13383,
1099
] | [
"Humans",
"Spinal Injuries",
"Tomography, X-Ray Computed"
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} |
29488706 | BCN Checkpoint: same-day confirmation of reactive HIV rapid test with Point Of Care HIV-RNA accelerates linkage to care and reduces anxiety. | BACKGROUND: The introduction in 2006 of the rapid HIV test by BCN Checkpoint in a non-clinical setting has been a successful step forwards in the uptake of testing. Nevertheless, HIV serostatus should be reported as HIV positive only when a reactive result has been tested again using a different assay (WHO guidelines 2... | [
637,
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2700,
420,
3,
3114,
13097,
1998,
131
] | [
"Anxiety",
"Diagnostic Services",
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"Molecular Diagnostic Techniques",
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} |
8304033 | Antithrombin III in fetuses and newborn children. | Antithrombin III (AT III) was measured in plasma of healthy fetuses between 20-29 weeks of gestation, in plasma of suspected growth retarded or malformed fetuses between 30-39 weeks of gestation, in healthy newborn infants after delivery, and in healthy infants during the first year of life. Measurements were performed... | [
7550,
5080,
2,
288,
2410,
2102,
3,
229,
35,
20,
2104
] | [
"Antithrombin III",
"Congenital Abnormalities",
"Female",
"Fetal Blood",
"Fetal Growth Retardation",
"Gestational Age",
"Humans",
"Infant, Newborn",
"Male",
"Pregnancy",
"Pregnancy Trimester, Third"
] | {
"A": 1,
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} |
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