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wikidoc
RAB11A
RAB11A Ras-related protein Rab-11A is a protein that in humans is encoded by the RAB11A gene. # Function The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Rab-11a cont...
RAB11A Ras-related protein Rab-11A is a protein that in humans is encoded by the RAB11A gene.[1][2] # Function The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.[3] Ra...
https://www.wikidoc.org/index.php/RAB11A
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wikidoc
RAB11B
RAB11B Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. Rab11b is reported as most abundantly expressed in brain, heart and testes. Rab (Ras-related in brain) proteins form the largest section of the Ras superfamily of small GTPases. The Rab family proteins regulate intracellular m...
RAB11B Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene.[1][2] Rab11b is reported as most abundantly expressed in brain, heart and testes. Rab (Ras-related in brain) proteins form the largest section of the Ras superfamily of small GTPases. The Rab family proteins regulate intracel...
https://www.wikidoc.org/index.php/RAB11B
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wikidoc
RABEPK
RABEPK Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene. Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network. # Interactions RABEPK has been show...
RABEPK Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.[1][2] Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.[1] # Interactions RABEPK has...
https://www.wikidoc.org/index.php/RABEPK
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wikidoc
RAD23B
RAD23B UV excision repair protein RAD23 homolog B is a protein that in humans is encoded by the RAD23B gene. # Function The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was found to be a component of th...
RAD23B UV excision repair protein RAD23 homolog B is a protein that in humans is encoded by the RAD23B gene.[1][2] # Function The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was found to be a componen...
https://www.wikidoc.org/index.php/RAD23B
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wikidoc
RAD51C
RAD51C RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. # Function The RAD51C protein is one of five paralogs of RAD51, including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence ident...
RAD51C RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene.[1][2] # Function The RAD51C protein is one of five paralogs of RAD51, including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequenc...
https://www.wikidoc.org/index.php/RAD51C
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wikidoc
RAD54B
RAD54B DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene. The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and rep...
RAD54B DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.[1][2][3] The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombinati...
https://www.wikidoc.org/index.php/RAD54B
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wikidoc
RANBP1
RANBP1 Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene. Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedl...
RANBP1 Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene.[1][2][3] Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but do...
https://www.wikidoc.org/index.php/RANBP1
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wikidoc
RANBP2
RANBP2 RAN binding protein 2 (RANBP2) is protein which in humans is encoded by the RANBP2 gene. It is also known as nucleoporin 358 (Nup358) since it is a member nucleoporin family that makes up the nuclear pore complex. RanBP2 has a mass of 358 kDa. # Function RAN is a small GTP-binding protein of the RAS superfamily...
RANBP2 RAN binding protein 2 (RANBP2) is protein which in humans is encoded by the RANBP2 gene.[1] It is also known as nucleoporin 358 (Nup358) since it is a member nucleoporin family that makes up the nuclear pore complex. RanBP2 has a mass of 358 kDa. # Function RAN is a small GTP-binding protein of the RAS superfa...
https://www.wikidoc.org/index.php/RANBP2
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wikidoc
RASSF1
RASSF1 Ras association domain-containing protein 1 is a protein that in humans is encoded by the RASSF1 gene. # Function This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor ...
RASSF1 Ras association domain-containing protein 1 is a protein that in humans is encoded by the RASSF1 gene. # Function This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor...
https://www.wikidoc.org/index.php/RASSF1
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wikidoc
RASSF5
RASSF5 Ras association domain-containing protein 5 is a protein that in humans is encoded by the RASSF5 or F5 gene. # Function This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and mic...
RASSF5 Ras association domain-containing protein 5 is a protein that in humans is encoded by the RASSF5 or F5 gene.[1][2][3] # Function This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosom...
https://www.wikidoc.org/index.php/RASSF5
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wikidoc
RASSF9
RASSF9 Ras association domain-containing protein 9 (RASSF9), also known as PAM COOH-terminal interactor protein 1 (PCIP1) or peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor (PAMCI) is a protein that in humans is encoded by the RASSF9 gene. # Function RASSF9 the N-terminal RASSF family member Ras...
RASSF9 Ras association domain-containing protein 9 (RASSF9), also known as PAM COOH-terminal interactor protein 1 (PCIP1) or peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor (PAMCI) is a protein that in humans is encoded by the RASSF9 gene.[1] # Function RASSF9 the N-terminal RASSF family member...
https://www.wikidoc.org/index.php/RASSF9
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wikidoc
RBFOX1
RBFOX1 Fox-1 homolog A, also known as ataxin 2-binding protein 1 (A2BP1) or hexaribonucleotide-binding protein 1 (HRNBP1) or RNA binding protein, fox-1 homolog (Rbfox1), is a protein that in humans is encoded by the RBFOX1 gene. # Function Rbfox1 has an RNA recognition motif that is highly conserved among RNA-binding...
RBFOX1 Fox-1 homolog A, also known as ataxin 2-binding protein 1 (A2BP1) or hexaribonucleotide-binding protein 1 (HRNBP1) or RNA binding protein, fox-1 homolog (Rbfox1), is a protein that in humans is encoded by the RBFOX1 gene.[1] # Function Rbfox1 has an RNA recognition motif that is highly conserved among RNA-bin...
https://www.wikidoc.org/index.php/RBFOX1
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wikidoc
RECQL4
RECQL4 ATP-dependent DNA helicase Q4 is an enzyme that in humans is encoded by the RECQL4 gene. Mutations in RECQL4 are associated with the autosomal recessive disease Rothmund-Thomson Syndrome, a disorder that has features of premature aging. In addition to the Rothmund-Thomson syndrome, RECQL4 mutations are also ass...
RECQL4 ATP-dependent DNA helicase Q4 is an enzyme that in humans is encoded by the RECQL4 gene.[1][2][3] Mutations in RECQL4 are associated with the autosomal recessive disease Rothmund-Thomson Syndrome, a disorder that has features of premature aging.[4][5] In addition to the Rothmund-Thomson syndrome, RECQL4 mutati...
https://www.wikidoc.org/index.php/RECQL4
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wikidoc
RHBDF2
RHBDF2 Rhomboid family member 2 is a protein that in humans is encoded by the RHBDF2 gene. The alternative name iRhom2 has been proposed, in order to clarify that it is a catalytically inactive member of the rhomboid family of intramembrane serine proteases. The RHBDF2 gene is located on the long arm of chromosome 17 (...
RHBDF2 Rhomboid family member 2 is a protein that in humans is encoded by the RHBDF2 gene.[1][2] The alternative name iRhom2 has been proposed, in order to clarify that it is a catalytically inactive member of the rhomboid family of intramembrane serine proteases.[3][4] The RHBDF2 gene is located on the long arm of ch...
https://www.wikidoc.org/index.php/RHBDF2
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wikidoc
RICTOR
RICTOR Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene. RICTOR and mTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. # Structure The gene RICTOR is located on ...
RICTOR Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene.[1][2] RICTOR and mTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.[2] # Structure The gene RICTOR is l...
https://www.wikidoc.org/index.php/RICTOR
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wikidoc
RIPOR2
RIPOR2 RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene. # Function The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative splici...
RIPOR2 RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene.[1] # Function The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative sp...
https://www.wikidoc.org/index.php/RIPOR2
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wikidoc
RMND5B
RMND5B Required for meiotic nuclear division 5 homolog B (S. cerevisiae), also known as RMND5B, is a protein which in humans is encoded by the RMND5B gene. It has a zinc finger domain and is highly conserved throughout many eukaryotic organisms. # Protein sequence This protein is rich in leucine (14.0%) and might bel...
RMND5B Required for meiotic nuclear division 5 homolog B (S. cerevisiae), also known as RMND5B, is a protein which in humans is encoded by the RMND5B gene.[1] It has a zinc finger domain and is highly conserved throughout many eukaryotic organisms. # Protein sequence This protein is rich in leucine (14.0%) and might...
https://www.wikidoc.org/index.php/RMND5B
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wikidoc
RNF111
RNF111 E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene. # Function The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been sho...
RNF111 E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene.[1][2] # Function The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has b...
https://www.wikidoc.org/index.php/RNF111
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wikidoc
RSPH4A
RSPH4A Radial spoke head protein 4 homolog A, also known as radial spoke head-like protein 3, is a protein that in humans is encoded by the RSPH4A gene. # Function TRadial spoke head protein 4 homolog A appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate ...
RSPH4A Radial spoke head protein 4 homolog A, also known as radial spoke head-like protein 3, is a protein that in humans is encoded by the RSPH4A gene.[1][2] # Function TRadial spoke head protein 4 homolog A appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflag...
https://www.wikidoc.org/index.php/RSPH4A
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wikidoc
RSPH6A
RSPH6A Radial spoke head protein 6 homolog A (RSPH6A) also known as radial spoke head-like protein 1 (RSHL1) is a protein that in humans is encoded by the RSPH6A gene. # Function Radial spoke head protein 6 homolog A is similar to a sea urchin radial spoke head protein. Radial spoke protein complexes form part of the ...
RSPH6A Radial spoke head protein 6 homolog A (RSPH6A) also known as radial spoke head-like protein 1 (RSHL1) is a protein that in humans is encoded by the RSPH6A gene.[1][2] # Function Radial spoke head protein 6 homolog A is similar to a sea urchin radial spoke head protein. Radial spoke protein complexes form part ...
https://www.wikidoc.org/index.php/RSPH6A
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wikidoc
RUVBL2
RUVBL2 RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins. # Function This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand br...
RUVBL2 RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins. # Function This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand b...
https://www.wikidoc.org/index.php/RUVBL2
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wikidoc
Radish
Radish The radish (Raphanus sativus) is an edible root vegetable of the Brassicaceae family that is grown and consumed throughout the world. # History Although the radish was a well-established crop in Hellenistic and Roman times, which leads to the assumption that it was brought into cultivation at an earlier time, Z...
Radish Template:Otheruses4 The radish (Raphanus sativus) is an edible root vegetable of the Brassicaceae family that is grown and consumed throughout the world. # History Template:Refimprovesect Although the radish was a well-established crop in Hellenistic and Roman times, which leads to the assumption that it was b...
https://www.wikidoc.org/index.php/Radish
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wikidoc
Ranula
Ranula # Overview A ranula is a type of mucocele found on the floor of the mouth. Ranulas present as a swelling of connective tissue consisting of collected mucin from a ruptured salivary gland duct, which is usually caused by local trauma. # Etymology The latin rana means frog, and a ranula is so named because its ...
Ranula Template:DiseaseDisorder infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Berna Zorkun DMD [2] # Overview A ranula is a type of mucocele found on the floor of the mouth. Ranulas present as a swelling of connective tissue consisting of collected mucin from a ruptured saliva...
https://www.wikidoc.org/index.php/Ranula
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wikidoc
RasMol
RasMol # Overview RasMol is a computer program written for molecular graphics visualization intended and used primarily for the depiction and exploration of biological macromolecule structures, such as those found in the Protein Data Bank. It was originally developed by Roger Sayle in the early 90s. Historically, it ...
RasMol # Overview RasMol is a computer program written for molecular graphics visualization intended and used primarily for the depiction and exploration of biological macromolecule structures, such as those found in the Protein Data Bank. It was originally developed by Roger Sayle in the early 90s. Historically, it ...
https://www.wikidoc.org/index.php/RasMol
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wikidoc
RecLOH
RecLOH RecLOH is a term in genetics that is an abbreviation for "Recombinational Loss of Heterozygosity". This is a type of mutation which occurs with DNA by recombination. From a pair of equivalent ("homologous"), but slightly different genes, a pair of identical genes results. In this case there is an unreciprocal ex...
RecLOH RecLOH is a term in genetics that is an abbreviation for "Recombinational Loss of Heterozygosity". This is a type of mutation which occurs with DNA by recombination. From a pair of equivalent ("homologous"), but slightly different genes, a pair of identical genes results. In this case there is an unreciprocal e...
https://www.wikidoc.org/index.php/RecLOH
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wikidoc
Rectal
Rectal # Overview The rectum (from the Latin rectum intestinum, meaning straight intestine) is the final straight portion of the large intestine in some mammals, and the gut in others, terminating in the anus. The human rectum is about 12 cm long. At its commencement its caliber is similar to that of the sigmoid colon...
Rectal # Overview Template:Infobox Anatomy The rectum (from the Latin rectum intestinum, meaning straight intestine) is the final straight portion of the large intestine in some mammals, and the gut in others, terminating in the anus. The human rectum is about 12 cm long. At its commencement its caliber is similar to ...
https://www.wikidoc.org/index.php/Rectal
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wikidoc
Red 2G
Red 2G Red 2G is a synthetic red azo dye. It is soluble in water and slightly soluble in ethanol. It usually comes as a disodium salt of 8-actamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulphonate. # Uses ## Food dye In the European Union, Red 2G is used as a food dye (E number E128). However, it is only permitted ...
Red 2G Template:Chembox new Red 2G is a synthetic red azo dye. It is soluble in water and slightly soluble in ethanol. It usually comes as a disodium salt of 8-actamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulphonate. # Uses ## Food dye In the European Union, Red 2G is used as a food dye (E number E128). However,...
https://www.wikidoc.org/index.php/Red_2G
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wikidoc
Reelin
Reelin Reelin (RELN) is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell-cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates synapt...
Reelin Reelin (RELN)[1] is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell-cell interactions. Besides this important role in early development, reelin continues to work in the adult brain.[2] It modulates...
https://www.wikidoc.org/index.php/Reelin
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wikidoc
Reflux
Reflux # Overview Reflux is a technique used in industrial and laboratory distillations. It is also used in chemistry to apply energy to reactions over a long time. # Reflux in industrial distillation The term reflux is very widely used in industries that utilize large-scale distillation columns and fractionators su...
Reflux # Overview Reflux is a technique used in industrial and laboratory distillations. It is also used in chemistry to apply energy to reactions over a long time. # Reflux in industrial distillation The term reflux [1][2] is very widely used in industries that utilize large-scale distillation columns and fractionat...
https://www.wikidoc.org/index.php/Reflux
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wikidoc
Remedy
Remedy Def. "a medicine, application, or treatment that relieves or cures a disease" is called a remedy. # Cures Def. a "method, device or medication that restores good health" or an act "of healing or state of being healed; restoration to health after a disease, or to soundness after injury" is called a cure. # Medi...
Remedy Associate Editor(s)-in-Chief: Henry A. Hoff Def. "a medicine, application, or treatment that relieves or cures a disease"[1] is called a remedy. # Cures Def. a "method, device or medication that restores good health"[2] or an act "of healing or state of being healed; restoration to health after a disease, or ...
https://www.wikidoc.org/index.php/Remedy
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wikidoc
Rennet
Rennet Rennet (Template:PronEng) is a natural complex of enzymes produced in any mammalian stomach to digest the mother's milk. Rennet contains a proteolytic enzyme (protease) that coagulates the milk, causing it to separate into solids (curds) and liquid (whey). The active enzyme in rennet is called rennin or chymosi...
Rennet Rennet (Template:PronEng) is a natural complex of enzymes produced in any mammalian stomach to digest the mother's milk. Rennet contains a proteolytic enzyme (protease) that coagulates the milk, causing it to separate into solids (curds) and liquid (whey). The active enzyme in rennet is called rennin or chymos...
https://www.wikidoc.org/index.php/Rennet
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wikidoc
Result
Result A result is the final consequence of a sequence of actions or events (broadly incidents and accidents) expressed qualitatively or quantitatively, being a loss, injury, disadvantage, advantage, gain, victory or simply a value. There may be a range of possible outcomes associated with an event possibly depending o...
Result Click here for the drug result. A result is the final consequence of a sequence of actions or events (broadly incidents and accidents) expressed qualitatively or quantitatively, being a loss, injury, disadvantage, advantage, gain, victory or simply a value. There may be a range of possible outcomes associated w...
https://www.wikidoc.org/index.php/Result
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wikidoc
RhoBTB
RhoBTB The RhoBTB family is a subgroup of the Rho family of small GTPases. They are a highly divergent class and are all characterized by an N-terminal Rho-related domain followed by at least one C-terminal BTB domain. # Discovery The RhoBTB family of molecules was unknowingly discovered in 1993 by analyzing the Dict...
RhoBTB The RhoBTB family is a subgroup of the Rho family of small GTPases. They are a highly divergent class and are all characterized by an N-terminal Rho-related domain followed by at least one C-terminal BTB domain. # Discovery The RhoBTB family of molecules was unknowingly discovered in 1993 by analyzing the Dic...
https://www.wikidoc.org/index.php/RhoBTB
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wikidoc
Ribose
Ribose Ribose (ɹˈaɪbəʊs, ɹˈaɪbəɹʊs), primarily seen as D-ribose, is an aldopentose — a monosaccharide containing five carbon atoms, and including an aldehyde functional group in its linear form. It has the chemical formula Template:Carbon5Template:Hydrogen10Template:Oxygen5, and was discovered in 1905 by Phoebus Leve...
Ribose Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ribose (ɹˈaɪbəʊs[1], ɹˈaɪbəɹʊs[2]), primarily seen as D-ribose, is an aldopentose — a monosaccharide containing five carbon atoms, and including an aldehyde functional group in its linear form. It has the chemical formula Template:Carbon5...
https://www.wikidoc.org/index.php/Ribose
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wikidoc
Ricola
Ricola Ricola AG is a well known manufacturer of cough drops and breath mints in Switzerland. The company focuses primarily on using herbal ingredients. # History The company was founded by Emil Wilhelm Richterich in 1930. Today 2007, it is managed by Felix Richterich. The company's name is an abbreviation of the word...
Ricola Template:Expand Ricola AG is a well known manufacturer of cough drops and breath mints in Switzerland. The company focuses primarily on using herbal ingredients. ### History The company was founded by Emil Wilhelm Richterich in 1930. Today 2007, it is managed by Felix Richterich. The company's name is an abbre...
https://www.wikidoc.org/index.php/Ricola
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wikidoc
Rodent
Rodent Rodentia is an order of mammals also known as rodents, characterised by two continuously-growing incisors in the upper and lower jaws which must be kept short by gnawing. Forty percent of mammal species are rodents, and they are found in vast numbers on all continents other than Antarctica. Common rodents inclu...
Rodent Rodentia is an order of mammals also known as rodents, characterised by two continuously-growing incisors in the upper and lower jaws which must be kept short by gnawing.[1][2] Forty percent of mammal species are rodents, and they are found in vast numbers on all continents other than Antarctica. Common rodent...
https://www.wikidoc.org/index.php/Rodent
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wikidoc
S100A1
S100A1 S100A1, also known as S100 calcium-binding protein A1 is a protein which in humans is encoded by the S100A1 gene. S100A1 is highly expressed in cardiac and skeletal muscle, and localizes to Z-discs and sarcoplasmic reticulum. S100A1 has shown promise as an effective candidate for gene therapy to treat post-myoc...
S100A1 S100A1, also known as S100 calcium-binding protein A1 is a protein which in humans is encoded by the S100A1 gene.[1][2] S100A1 is highly expressed in cardiac and skeletal muscle, and localizes to Z-discs and sarcoplasmic reticulum. S100A1 has shown promise as an effective candidate for gene therapy to treat po...
https://www.wikidoc.org/index.php/S100A1
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wikidoc
S100A4
S100A4 S100 calcium-binding protein A4 (S100A4) is a protein that in humans is encoded by the S100A4 gene. # Function The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of c...
S100A4 S100 calcium-binding protein A4 (S100A4) is a protein that in humans is encoded by the S100A4 gene.[1] # Function The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range ...
https://www.wikidoc.org/index.php/S100A4
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wikidoc
S100A6
S100A6 S100 calcium-binding protein A6 (S100A6) is a protein that in humans is encoded by the S100A6 gene. # Function The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of c...
S100A6 S100 calcium-binding protein A6 (S100A6) is a protein that in humans is encoded by the S100A6 gene.[1] # Function The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range ...
https://www.wikidoc.org/index.php/S100A6
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wikidoc
S100A7
S100A7 S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. # Function S100A7 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of c...
S100A7 S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene.[1] # Function S100A7 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range ...
https://www.wikidoc.org/index.php/S100A7
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wikidoc
S100A9
S100A9 S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene. The proteins S100A8 and S100A9 form a heterodimer called calprotectin. # Function S100-A9 is a member of the S100 family of pr...
S100A9 S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene.[1] The proteins S100A8 and S100A9 form a heterodimer called calprotectin. # Function S100-A9 is a member of the S100 family o...
https://www.wikidoc.org/index.php/S100A9
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wikidoc
SADDAN
SADDAN # Overview SADDAN (severe achondroplasia with developmental delay and acanthosis nigricans) is a rare inherited disorder of bone growth characterized by skeletal, brain, and skin abnormalities. All people with this condition are extremely short with particularly short arms and legs. Other signs and symptoms inc...
SADDAN # Overview SADDAN (severe achondroplasia with developmental delay and acanthosis nigricans) is a rare inherited disorder of bone growth characterized by skeletal, brain, and skin abnormalities. All people with this condition are extremely short with particularly short arms and legs. Other signs and symptoms inc...
https://www.wikidoc.org/index.php/SADDAN
bd2c408be09b401bebe085fdddc91aa895c779f4
wikidoc
SAMHD1
SAMHD1 SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. SAMHD1 is a cellular enzyme, responsible for blocking replication of HIV in dendritic cells, macrophages and monocytes. It is an enzyme that exhibits phosphohydrolase activity, converting deoxynucleoside trip...
SAMHD1 SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. SAMHD1 is a cellular enzyme, responsible for blocking replication of HIV in dendritic cells,[1] macrophages[2] and monocytes.[3] It is an enzyme that exhibits phosphohydrolase activity,[4][5] converting deox...
https://www.wikidoc.org/index.php/SAMHD1
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wikidoc
SAP130
SAP130 Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene. # Function SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003). # Interactions SAP130 has been shown to interact wit...
SAP130 Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.[1][2][3] # Function SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003).[supplied by OMIM][3] # Interactions SAP130...
https://www.wikidoc.org/index.php/SAP130
4dbf6e712fd400452cf84e18e8e47909dbfbd390
wikidoc
SCARB1
SCARB1 Scavenger receptor class B type 1 (SRB1) also known as SR-BI is a protein that in humans is encoded by the SCARB1 gene. SR-BI functions as a receptor for high-density lipoprotein. # Function Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, includin...
SCARB1 Scavenger receptor class B type 1 (SRB1) also known as SR-BI is a protein that in humans is encoded by the SCARB1 gene.[1] SR-BI functions as a receptor for high-density lipoprotein.[2] # Function Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, i...
https://www.wikidoc.org/index.php/SCARB1
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wikidoc
SCARB2
SCARB2 Lysosome membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene. LIMP-2 is expressed in brain, heart, liver, lung and kidney, mainly in the membrane of lysosome organelles; however, in cardiac muscle, LIMP-2 is also expressed at intercalated discs. LIMP-2 in a membrane protein in l...
SCARB2 Lysosome membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene.[1] LIMP-2 is expressed in brain, heart, liver, lung and kidney, mainly in the membrane of lysosome organelles; however, in cardiac muscle, LIMP-2 is also expressed at intercalated discs. LIMP-2 in a membrane protein ...
https://www.wikidoc.org/index.php/SCARB2
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wikidoc
SCENAR
SCENAR The Scenar device, is the latest incarnation of an electronic instrument developed by scientists working in the Russian aerospace industry, in the town of Taganrog, Russia. The name is an acronym derived from "Self Controlled Energo-Neuro-adaptive Regulation". It has, in earlier incarnations been known as the "...
SCENAR Template:Infobox Organization The Scenar device, is the latest incarnation of an electronic instrument developed by scientists working in the Russian aerospace industry, in the town of Taganrog, Russia. The name is an acronym derived from "Self Controlled Energo-Neuro-adaptive Regulation". It has, in earlier in...
https://www.wikidoc.org/index.php/SCENAR
56f4fd11ba3f8214e0d65094330ba5850d1c8eb3
wikidoc
SCNN1A
SCNN1A The SCNN1A gene encodes for the α subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1B, SCNN1G, and SCNN1D. ENaC is expressed in epithelial cells and is dif...
SCNN1A The SCNN1A gene encodes for the α subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ.[1] The other ENAC subunits are encoded by SCNN1B, SCNN1G, and SCNN1D. ENaC is expressed in epithelial cells[1] and...
https://www.wikidoc.org/index.php/SCNN1A
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wikidoc
SCNN1B
SCNN1B The SCNN1B gene encodes for the β subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1G, and SCNN1D. ENaC is expressed in epithelial cells and is dif...
SCNN1B The SCNN1B gene encodes for the β subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1G, and SCNN1D.[1] ENaC is expressed in epithelial cells[1] and...
https://www.wikidoc.org/index.php/SCNN1B
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wikidoc
SCNN1D
SCNN1D The SCNN1D gene encodes for the δ (delta) subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1B, and SCNN1G. ENaC is expressed in epithelial cells an...
SCNN1D The SCNN1D gene encodes for the δ (delta) subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ.[1] The other ENAC subunits are encoded by SCNN1A, SCNN1B, and SCNN1G. ENaC is expressed in epithelial cell...
https://www.wikidoc.org/index.php/SCNN1D
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wikidoc
SCNN1G
SCNN1G The SCNN1G gene encodes for the γ subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1B, and SCNN1D. ENaC is expressed in epithelial cells and is dif...
SCNN1G The SCNN1G gene encodes for the γ subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1B, and SCNN1D.[1] ENaC is expressed in epithelial cells and is...
https://www.wikidoc.org/index.php/SCNN1G
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wikidoc
SDHAF1
SDHAF1 Succinate dehydrogenase complex assembly factor 1 (SDHAF1), also known as LYR motif-containing protein 8 (LYRM8), is a protein that in humans is encoded by the SDHAF1, or LYRM8, gene. SDHAF1 is a chaperone protein involved in the assembly of the succinate dehydrogenase (SDH) complex (complex II). Mutations in th...
SDHAF1 Succinate dehydrogenase complex assembly factor 1 (SDHAF1), also known as LYR motif-containing protein 8 (LYRM8), is a protein that in humans is encoded by the SDHAF1, or LYRM8, gene. SDHAF1 is a chaperone protein involved in the assembly of the succinate dehydrogenase (SDH) complex (complex II). Mutations in t...
https://www.wikidoc.org/index.php/SDHAF1
6a31c34532b2e3c12753ee6287499425be84ee62
wikidoc
SDHAF2
SDHAF2 Succinate dehydrogenase complex assembly factor 2, formerly known as SDH5 and also known as SDH assembly factor 2 or SDHAF2 is a protein that in humans is encoded by the SDHAF2 gene. This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for act...
SDHAF2 Succinate dehydrogenase complex assembly factor 2, formerly known as SDH5 and also known as SDH assembly factor 2 or SDHAF2 is a protein that in humans is encoded by the SDHAF2 gene. This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for ac...
https://www.wikidoc.org/index.php/SDHAF2
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wikidoc
SEC16B
SEC16B Protein transport protein Sec16B also known as regucalcin gene promoter region-related protein p117 (RGPR-p117) and leucine zipper transcription regulator 2 (LZTR2) is a protein that in humans is encoded by the SEC16B gene. # Discovery RGPR-p117/SEC16B, which was named as a regucalcin gene promoter region-relat...
SEC16B Protein transport protein Sec16B also known as regucalcin gene promoter region-related protein p117 (RGPR-p117) and leucine zipper transcription regulator 2 (LZTR2) is a protein that in humans is encoded by the SEC16B gene.[1][2][3] # Discovery RGPR-p117/SEC16B, which was named as a regucalcin gene promoter re...
https://www.wikidoc.org/index.php/SEC16B
d1c6ed54554f5d9ac0568ebf704759556ccb21bc
wikidoc
SEC23A
SEC23A Sec23 homolog A (S. cerevisiae), also known as SEC23A, is a protein which in humans is encoded by the SEC23A gene. # Function The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It contains a gelsolin domain. It is part of a protein complex and found in the ribosome-fr...
SEC23A Sec23 homolog A (S. cerevisiae), also known as SEC23A, is a protein which in humans is encoded by the SEC23A gene.[1] # Function The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It contains a gelsolin domain.[2] It is part of a protein complex and found in the ribo...
https://www.wikidoc.org/index.php/SEC23A
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wikidoc
SEC23B
SEC23B Protein transport protein Sec23B is a protein that in humans is encoded by the SEC23B gene. The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the ...
SEC23B Protein transport protein Sec23B is a protein that in humans is encoded by the SEC23B gene.[1][2][3] The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COP...
https://www.wikidoc.org/index.php/SEC23B
271e39344ddc702aaded6dff528f75eaeac0bfc7
wikidoc
SEC24A
SEC24A SEC24 family, member A (S. cerevisiae) is a protein that in humans is encoded by the SEC24A gene. The protein belongs to a protein family that are homologous to yeast Sec24. It is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. # Model organi...
SEC24A SEC24 family, member A (S. cerevisiae) is a protein that in humans is encoded by the SEC24A gene.[1] The protein belongs to a protein family that are homologous to yeast Sec24.[2] It is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum.[1] # Mo...
https://www.wikidoc.org/index.php/SEC24A
511c27da588b1259898ab08d615b7aeff5f235a1
wikidoc
SEMA3A
SEMA3A Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. # Function The SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted Sema3A protein can function as either a chemorepulsiv...
SEMA3A Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene.[1][2][3] # Function The SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted Sema3A protein can function as either a che...
https://www.wikidoc.org/index.php/SEMA3A
d85d18b1c8c02a0c93443dbc2d2a8fc543a3bcbd
wikidoc
SEMA4A
SEMA4A Semaphorin-4A is a protein that in humans is encoded by the SEMA4A gene. # Function SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses. # Clinical significance A germline...
SEMA4A Semaphorin-4A is a protein that in humans is encoded by the SEMA4A gene.[1][2] # Function SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.[supplied by OMIM][2] # Clin...
https://www.wikidoc.org/index.php/SEMA4A
801e2795f3e137080cea357778a12ca7422bc2db
wikidoc
SEMA4D
SEMA4D Semaphorin-4D (SEMA4D) also known as Cluster of Differentiation 100 (CD100), is a protein of the semaphorin family that in humans is encoded by the SEMA4D gene. # Function Semaphorin 4D (Sema 4D) is an axon guidance molecule which is secreted by oligodendrocytes and induces growth cone collapse in the central n...
SEMA4D Semaphorin-4D (SEMA4D) also known as Cluster of Differentiation 100 (CD100), is a protein of the semaphorin family that in humans is encoded by the SEMA4D gene.[1] # Function Semaphorin 4D (Sema 4D) is an axon guidance molecule which is secreted by oligodendrocytes and induces growth cone collapse in the centr...
https://www.wikidoc.org/index.php/SEMA4D
b66f9a62320aa4f9cd8dbbd94d0a5c4d3bb3365d
wikidoc
SEMA5A
SEMA5A Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene. Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996). Semaphorine 5A also plays a role in autism, reducing the ability of neurons to form connections with o...
SEMA5A Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene.[1][2][3] Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996).[supplied by OMIM][3] Semaphorine 5A also plays a role in autism, reducing the ability of neu...
https://www.wikidoc.org/index.php/SEMA5A
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wikidoc
SERAC1
SERAC1 Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded...
SERAC1 Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene.[1][2][3] The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. T...
https://www.wikidoc.org/index.php/SERAC1
4d89b6954d66cee2938044be2bd1fd06ab24b3eb
wikidoc
SETBP1
SETBP1 SET binding protein 1 is a protein that in humans is encoded by the SETBP1 gene. # Gene The gene is located on Chromosome 18, specifically on the long (q) arm of the chromosome at position 12.3. This is also written as 18q12.3. # Function The SETBP1 gene provides instructions for making a protein known as the ...
SETBP1 SET binding protein 1 is a protein that in humans is encoded by the SETBP1 gene.[1] # Gene The gene is located on Chromosome 18, specifically on the long (q) arm of the chromosome at position 12.3. This is also written as 18q12.3. # Function The SETBP1 gene provides instructions for making a protein known as ...
https://www.wikidoc.org/index.php/SETBP1
644d598b1b18944a0dc7f055e939b8d92bc80962
wikidoc
SETDB1
SETDB1 Histone-lysine N-methyltransferase SETDB1 is an enzyme that in humans is encoded by the SETDB1 gene.SETDB1 is also known as KMT1E or H3K9 methyltransferase ESET. # Function The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was origin...
SETDB1 Histone-lysine N-methyltransferase SETDB1 is an enzyme that in humans is encoded by the SETDB1 gene.[1][2]SETDB1 is also known as KMT1E or H3K9 methyltransferase ESET. # Function The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was...
https://www.wikidoc.org/index.php/SETDB1
2448e638abf1ca82d95c759b40245bd8b7bbfb4f
wikidoc
SETMAR
SETMAR Histone-lysine N-methyltransferase SETMAR is an enzyme that in humans is encoded by the SETMAR gene. # Model organisms Model organisms have been used in the study of SETMAR function. A conditional knockout mouse line, called Setmartm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consor...
SETMAR Histone-lysine N-methyltransferase SETMAR is an enzyme that in humans is encoded by the SETMAR gene.[1][2] # Model organisms Model organisms have been used in the study of SETMAR function. A conditional knockout mouse line, called Setmartm1a(EUCOMM)Wtsi[9][10] was generated as part of the International Knockou...
https://www.wikidoc.org/index.php/SETMAR
46e3901f7bf5202d8309d2f7e4b970c2622105bb
wikidoc
SH2D3C
SH2D3C SH2 domain containing 3C, also known as SH2D3C, is a protein that in humans is encoded by the SH2D3C gene. # Function Sh2d3c is a gene on human chromosome 9 that encodes an SH2 domain containing protein known as NSP3. The mouse homologue is found on chromosome 2. The NSP (Novel SH2-containing Protein) family ...
SH2D3C SH2 domain containing 3C, also known as SH2D3C, is a protein that in humans is encoded by the SH2D3C gene.[1] # Function Sh2d3c is a gene on human chromosome 9 that encodes an SH2 domain containing protein known as NSP3. The mouse homologue is found on chromosome 2. The NSP (Novel SH2-containing Protein) fam...
https://www.wikidoc.org/index.php/SH2D3C
b22dd03dcb4a9f6b26187eb7b2c288c546f29064
wikidoc
SH3D21
SH3D21 SH3D21 is a nuclear protein that is encoded by the SH3D21 gene. In humans, this gene is located on chromosome 1 p34.3. The human mRNA transcript is 2527 base pairs and the final protein product is 756 amino acids. While the exact function of this protein remains unknown, due to the presence of three SH3 domain...
SH3D21 SH3D21 is a nuclear protein that is encoded by the SH3D21 gene. In humans, this gene is located on chromosome 1 p34.3.[1] The human mRNA transcript is 2527 base pairs and the final protein product is 756 amino acids.[2] While the exact function of this protein remains unknown, due to the presence of three SH3...
https://www.wikidoc.org/index.php/SH3D21
323ce9279a65593e2d61eb62b31738dd94ee9139
wikidoc
SH3TC2
SH3TC2 SH3 domain and tetratricopeptide repeats-containing protein 2 is a protein that in humans is encoded by the SH3TC2 gene. It is believed to be expressed in the Schwann cells that wrap the myelin sheath around nerves. # Function This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 t...
SH3TC2 SH3 domain and tetratricopeptide repeats-containing protein 2 is a protein that in humans is encoded by the SH3TC2 gene.[1][2] It is believed to be expressed in the Schwann cells that wrap the myelin sheath around nerves. # Function This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains a...
https://www.wikidoc.org/index.php/SH3TC2
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wikidoc
SHANK2
SHANK2 SH3 and multiple ankyrin repeat domains protein 2 is a protein that in humans is encoded by the SHANK2 gene. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. # Function This gene encodes a protein th...
SHANK2 SH3 and multiple ankyrin repeat domains protein 2 is a protein that in humans is encoded by the SHANK2 gene.[1][2] Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined.[2] # Function This gene encodes a ...
https://www.wikidoc.org/index.php/SHANK2
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wikidoc
SHANK3
SHANK3 SH3 and multiple ankyrin repeat domains 3 (Shank3), also known as proline-rich synapse-associated protein 2 (ProSAP2), is a protein that in humans is encoded by the SHANK3 gene on chromosome 22. Additional isoforms have been described for this gene but they have not yet been experimentally verified. # Function...
SHANK3 SH3 and multiple ankyrin repeat domains 3 (Shank3), also known as proline-rich synapse-associated protein 2 (ProSAP2), is a protein that in humans is encoded by the SHANK3 gene on chromosome 22.[1] Additional isoforms have been described for this gene but they have not yet been experimentally verified. # Func...
https://www.wikidoc.org/index.php/SHANK3
465e85605395ac59cf1d1b88b402247a692a0d3f
wikidoc
SKIV2L
SKIV2L Helicase SKI2W is an enzyme that in humans is encoded by the SKIV2L gene. This enzyme is a human homologue of yeast SKI2, which may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. The SKIV2L gene is located in the class III region of the major histocompatibility complex. DEA...
SKIV2L Helicase SKI2W is an enzyme that in humans is encoded by the SKIV2L gene.[1][2][3] This enzyme is a human homologue of yeast SKI2, which may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. The SKIV2L gene is located in the class III region of the major histocompatibility co...
https://www.wikidoc.org/index.php/SKIV2L
a452604291fa68519b294177b1e1c5add4cb619b
wikidoc
SLAMF1
SLAMF1 Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. Recently SLAMF1 has also been designated CD150 (cluster of differentiation 150). SLAMF1 belongs to the signaling lymphocytic activation molecule family. The interaction of SLAMF1 promoter and enhancers with the...
SLAMF1 Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene.[1][2] Recently SLAMF1 has also been designated CD150 (cluster of differentiation 150). SLAMF1 belongs to the signaling lymphocytic activation molecule family. The interaction of SLAMF1 promoter and enhancers w...
https://www.wikidoc.org/index.php/SLAMF1
293c7cb2b6676b59720cfad7c9132785e73e0b36
wikidoc
SLC1A2
SLC1A2 Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the SLC1A2 gene. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known....
SLC1A2 Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the SLC1A2 gene.[1][2] Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not...
https://www.wikidoc.org/index.php/SLC1A2
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wikidoc
SLC2A9
SLC2A9 Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene. This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may...
SLC2A9 Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene.[1][2][3] This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded p...
https://www.wikidoc.org/index.php/SLC2A9
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wikidoc
SLC3A2
SLC3A2 4F2 cell-surface antigen heavy chain is a protein that in humans is encoded by the SLC3A2 (solute carrier family 3 member 2) gene. SLC3A2 comprises the heavy subunit of the large neutral amino acid transporter (LAT1) that is also known as CD98 (cluster of differentiation 98). # Function SLC3A2 is a member of t...
SLC3A2 4F2 cell-surface antigen heavy chain is a protein that in humans is encoded by the SLC3A2 (solute carrier family 3 member 2) gene.[1][2] SLC3A2 comprises the heavy subunit of the large neutral amino acid transporter (LAT1) that is also known as CD98 (cluster of differentiation 98).[3][4] # Function SLC3A2 is ...
https://www.wikidoc.org/index.php/SLC3A2
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wikidoc
SLC4A2
SLC4A2 Anion exchange protein 2 (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene. AE2 is functionally similar to the Band 3 Cl−/HCO3− exchange protein. Mice have been used to explore the function of AE2. AE2 contributes to basolateral membrane HCO3− transport in the gastrointestinal tr...
SLC4A2 Anion exchange protein 2 (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene.[1][2] AE2 is functionally similar to the Band 3 Cl−/HCO3− exchange protein. Mice have been used to explore the function of AE2. AE2 contributes to basolateral membrane HCO3− transport in the gastrointest...
https://www.wikidoc.org/index.php/SLC4A2
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wikidoc
SLC4A4
SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 is a membrane transport protein that in humans is encoded by the SLC4A4 gene. # Function Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process ...
SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 is a membrane transport protein that in humans is encoded by the SLC4A4 gene.[1][2][3] # Function Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogeni...
https://www.wikidoc.org/index.php/SLC4A4
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wikidoc
SLC4A5
SLC4A5 Electrogenic sodium bicarbonate cotransporter 4 is a protein that in humans is encoded by the SLC4A5 gene. # Function This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular ...
SLC4A5 Electrogenic sodium bicarbonate cotransporter 4 is a protein that in humans is encoded by the SLC4A5 gene.[1][2][3] # Function This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intr...
https://www.wikidoc.org/index.php/SLC4A5
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wikidoc
SLC5A1
SLC5A1 Sodium/glucose cotransporter 1 also known as solute carrier family 5 member 1 is a protein that in humans is encoded by the SLC5A1 gene. # Function Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes. The role of...
SLC5A1 Sodium/glucose cotransporter 1 also known as solute carrier family 5 member 1 is a protein that in humans is encoded by the SLC5A1 gene.[1][2] # Function Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes. The ...
https://www.wikidoc.org/index.php/SLC5A1
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wikidoc
SLC7A9
SLC7A9 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 also known as SLC7A9 is a protein which in humans is encoded by the SLC7A9 gene. # Function This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affi...
SLC7A9 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 also known as SLC7A9 is a protein which in humans is encoded by the SLC7A9 gene.[1] # Function This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-...
https://www.wikidoc.org/index.php/SLC7A9
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wikidoc
SLC9A8
SLC9A8 Sodium/hydrogen exchanger 8 is a protein that in humans is encoded by the SLC9A8 gene. # Model organisms Model organisms have been used in the study of SLC9A8 function. A conditional knockout mouse line, called Slc9a8tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a...
SLC9A8 Sodium/hydrogen exchanger 8 is a protein that in humans is encoded by the SLC9A8 gene.[1][2] # Model organisms Model organisms have been used in the study of SLC9A8 function. A conditional knockout mouse line, called Slc9a8tm1a(KOMP)Wtsi[6][7] was generated as part of the International Knockout Mouse Consortiu...
https://www.wikidoc.org/index.php/SLC9A8
51ccff2bbbe08d83676e60e82cbc0b67d8386920
wikidoc
SLURP1
SLURP1 Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene. It exerts anti-inflammatory effects and acts as a tumor suppressor and antagonist of nicotine. # Function The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence....
SLURP1 Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene.[1][2][3] It exerts anti-inflammatory effects and acts as a tumor suppressor and antagonist of nicotine[4]. # Function The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring sig...
https://www.wikidoc.org/index.php/SLURP1
bf967133b2daf48e916fdb6678bb76f2a12bde7d
wikidoc
SNAP23
SNAP23 Synaptosomal-associated protein 23 is a protein that in humans is encoded by the SNAP23 gene. Two alternative transcript variants encoding different protein isoforms have been described for this gene. # Function Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated...
SNAP23 Synaptosomal-associated protein 23 is a protein that in humans is encoded by the SNAP23 gene.[1][2] Two alternative transcript variants encoding different protein isoforms have been described for this gene. # Function Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-ass...
https://www.wikidoc.org/index.php/SNAP23
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wikidoc
SNAP25
SNAP25 Synaptosomal nerve-associated protein 25 (SNAP-25) is a t-SNARE protein that is encoded by the SNAP25 gene in humans. SNAP-25 is a component of the trans-SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the sy...
SNAP25 Synaptosomal nerve-associated protein 25 (SNAP-25) is a t-SNARE protein that is encoded by the SNAP25 gene in humans.[1] SNAP-25 is a component of the trans-SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings th...
https://www.wikidoc.org/index.php/SNAP25
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wikidoc
SNAP29
SNAP29 Synaptosomal-associated protein 29 is a protein that in humans is encoded by the SNAP29 gene. # Function This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxi...
SNAP29 Synaptosomal-associated protein 29 is a protein that in humans is encoded by the SNAP29 gene.[1][2][3] # Function This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind...
https://www.wikidoc.org/index.php/SNAP29
a55f0836a38fcb2ddad863e7d6c582986ea011ae
wikidoc
SNAPAP
SNAPAP SNARE-associated protein Snapin is a protein that in humans is encoded by the SNAPIN gene. # Function SNAPAP is a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion. SNAPAP is also a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC...
SNAPAP SNARE-associated protein Snapin is a protein that in humans is encoded by the SNAPIN gene.[1][2][3] # Function SNAPAP is a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion.[1] SNAPAP is also a component of the ubiquitously expressed BLOC1 multisubunit protein ...
https://www.wikidoc.org/index.php/SNAPAP
b02b47540a131337f1c89fc502ef97172b01e569
wikidoc
SNAPC4
SNAPC4 snRNA-activating protein complex subunit 4 is a protein that in humans is encoded by the SNAPC4 gene. # Model organisms Model organisms have been used in the study of SNAPC4 function. A conditional knockout mouse line, called Snapc4tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consort...
SNAPC4 snRNA-activating protein complex subunit 4 is a protein that in humans is encoded by the SNAPC4 gene.[1][2] # Model organisms Model organisms have been used in the study of SNAPC4 function. A conditional knockout mouse line, called Snapc4tm1a(KOMP)Wtsi[7][8] was generated as part of the International Knockout ...
https://www.wikidoc.org/index.php/SNAPC4
385cb6cbcd407a871a1cd71de245d7c18173a33d
wikidoc
SNC-80
SNC-80 SNC-80 is an opioid analgesic drug used in scientific research. It was invented in 1994. SNC-80 was the first non-peptide drug developed that is a highly selective agonist for the δ-opioid receptor. It has been shown to produce useful analgesic, antidepressant and anxiolytic effects in animal studies, but its us...
SNC-80 SNC-80 is an opioid analgesic drug used in scientific research.[1] It was invented in 1994.[2] SNC-80 was the first non-peptide drug developed that is a highly selective agonist for the δ-opioid receptor.[3][4] It has been shown to produce useful analgesic,[5] antidepressant[6] and anxiolytic effects in animal ...
https://www.wikidoc.org/index.php/SNC-80
d6ad7d5e8e4eecfaffe4e5c43dc56c5155f85702
wikidoc
SNCAIP
SNCAIP Synphilin-1 is a protein that in humans is encoded by the SNCAIP gene. SNCAIP stands for "synuclein, alpha interacting protein" and can be signified by SNCAP_HUMAN, synphilin 1, synuclein, alpha interacting protein (synphilin), and SYPH1. # Function This gene encodes a protein containing several protein-protein...
SNCAIP Synphilin-1 is a protein that in humans is encoded by the SNCAIP gene.[1][2] SNCAIP stands for "synuclein, alpha interacting protein" and can be signified by SNCAP_HUMAN, synphilin 1, synuclein, alpha interacting protein (synphilin), and SYPH1. # Function This gene encodes a protein containing several protein-...
https://www.wikidoc.org/index.php/SNCAIP
82f4c4ff9bfe61d5ef19be738ef8907216a5b861
wikidoc
SORBS1
SORBS1 CAP/Ponsin protein, also known as Sorbin and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SORBS1 gene. CAP/Ponsin is part of a small family of adaptor proteins that regulate cell adhesion, growth factor signaling and cytoskeletal formation. CAP/Ponsin is mainly expressed in heart...
SORBS1 CAP/Ponsin protein, also known as Sorbin and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SORBS1 gene.[1][2][3] CAP/Ponsin is part of a small family of adaptor proteins that regulate cell adhesion, growth factor signaling and cytoskeletal formation. CAP/Ponsin is mainly expresse...
https://www.wikidoc.org/index.php/SORBS1
cb7d4f745e230541cb334673a36fd4bb1d8afbda
wikidoc
SORBS2
SORBS2 ArgBP2 protein, also referred to as Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the SORBS2 gene. ArgBP2 belongs to the a small family of adaptor proteins having sorbin homology (SOHO) domains. ArgBP2 is highly abundant in cardiac muscle cells at sarcomeric Z-disc structur...
SORBS2 ArgBP2 protein, also referred to as Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the SORBS2 gene.[1][2] ArgBP2 belongs to the a small family of adaptor proteins having sorbin homology (SOHO) domains. ArgBP2 is highly abundant in cardiac muscle cells at sarcomeric Z-disc s...
https://www.wikidoc.org/index.php/SORBS2
e984f2786c3337f8d9eeb48972ed57c5a5883d2d
wikidoc
SPATS1
SPATS1 Spermatogenesis associated serine rich 1 (SPATS1) is a protein which in humans is encoded by the SPATS1 gene. It is also known by the aliases Dishevelled-DEP domain interacting protein (DDIP), Spermatogenesis Associated 8 (SPATA8), and serin-rich spermatogenic protein 1 (SRSP1). A general idea of its chemical st...
SPATS1 Spermatogenesis associated serine rich 1 (SPATS1) is a protein which in humans is encoded by the SPATS1 gene. It is also known by the aliases Dishevelled-DEP domain interacting protein (DDIP), Spermatogenesis Associated 8 (SPATA8), and serin-rich spermatogenic protein 1 (SRSP1).[1] A general idea of its chemica...
https://www.wikidoc.org/index.php/SPATS1
353d81d7843a2bb5ffabb7e5064417ed8cf41d9c
wikidoc
SPRED1
SPRED1 Sprouty-related, EVH1 domain-containing protein 1 (Spread-1) is a protein that in humans is encoded by the SPRED1 gene located on chromosome 15q13.2 and has seven coding exons. # Function Spread-1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growt...
SPRED1 Sprouty-related, EVH1 domain-containing protein 1 (Spread-1) is a protein that in humans is encoded by the SPRED1 gene located on chromosome 15q13.2 and has seven coding exons.[1] # Function Spread-1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several g...
https://www.wikidoc.org/index.php/SPRED1
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wikidoc
SPTAN1
SPTAN1 Alpha II-spectrin, also known as Spectrin alpha chain, brain is a protein that in humans is encoded by the SPTAN1 gene. Alpha II-spectrin is expressed in a variety of tissues, and is highly expressed in cardiac muscle at Z-disc structures, costameres and at the sarcolemma membrane. Mutations in alpha II-spectrin...
SPTAN1 Alpha II-spectrin, also known as Spectrin alpha chain, brain is a protein that in humans is encoded by the SPTAN1 gene.[1][2][3] Alpha II-spectrin is expressed in a variety of tissues, and is highly expressed in cardiac muscle at Z-disc structures, costameres and at the sarcolemma membrane. Mutations in alpha I...
https://www.wikidoc.org/index.php/SPTAN1
b47d9fb3371aaa8ee15055edc591dacba1afab50
wikidoc
SPTBN1
SPTBN1 Spectrin beta chain, brain 1 is a protein that in humans is encoded by the SPTBN1 gene. # Function Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, a...
SPTBN1 Spectrin beta chain, brain 1 is a protein that in humans is encoded by the SPTBN1 gene.[1] # Function Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane protein...
https://www.wikidoc.org/index.php/SPTBN1
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wikidoc
SRD5A1
SRD5A1 3-oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene. It is one of three forms of 5α-reductase. Steroid 5α-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). There are 3 isoforms of the enzyme: SRD5A1,...
SRD5A1 3-oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene.[1] It is one of three forms of 5α-reductase. Steroid 5α-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). There are 3 isoforms of the enzyme: SRD...
https://www.wikidoc.org/index.php/SRD5A1
f24f5be85e85b94d14833c64beddb6cc30cb49c0
wikidoc
SRD5A2
SRD5A2 3-oxo-5α-steroid 4-dehydrogenase 2 is an enzyme that in humans is encoded by the SRD5A2 gene. It is one of three forms of 5α-reductase. Steroid 5α-reductase catalyzes the conversion of the male sex hormone testosterone into the more potent androgen, dihydrotestosterone. This gene encodes a microsomal protein exp...
SRD5A2 3-oxo-5α-steroid 4-dehydrogenase 2 is an enzyme that in humans is encoded by the SRD5A2 gene.[1][2] It is one of three forms of 5α-reductase. Steroid 5α-reductase catalyzes the conversion of the male sex hormone testosterone into the more potent androgen, dihydrotestosterone. This gene encodes a microsomal prot...
https://www.wikidoc.org/index.php/SRD5A2
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wikidoc
SRGAP2
SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) also known as formin-binding protein 2 (FNBP2) is a protein that in humans is encoded by the SRGAP2 gene. SRGAP2 is involved in neuronal migration and neuronal differentiation. SRGAP2 also plays a critical role in synaptic development, brain mass and the number ...
SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) also known as formin-binding protein 2 (FNBP2) is a protein that in humans is encoded by the SRGAP2 gene.[1][2] SRGAP2 is involved in neuronal migration and neuronal differentiation.[3] SRGAP2 also plays a critical role in synaptic development,[4] brain mass an...
https://www.wikidoc.org/index.php/SRGAP2
844e0dad53abe8d2c0f32e4906928e61b48e1447
wikidoc
SS18L1
SS18L1 SS18-like protein 1 is a protein that in humans is encoded by the SS18L1 gene. # Function Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gen...
SS18L1 SS18-like protein 1 is a protein that in humans is encoded by the SS18L1 gene.[1] # Function Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18...
https://www.wikidoc.org/index.php/SS18L1
32fe5a4a77bd9a2288e77fba336c67f3dcd52224
wikidoc
SSMEM1
SSMEM1 Serine-rich single pass membrane protein 1 is a protein that in humans is encoded by the SSMEM1 gene. # Gene The gene and intron-exon structure were first predicted through analysis of the complete sequence of human chromosome 7, its initial designation being C7orf45. Human mRNA transcripts were identified thr...
SSMEM1 Serine-rich single pass membrane protein 1 is a protein that in humans is encoded by the SSMEM1 gene.[1] # Gene The gene and intron-exon structure were first predicted through analysis of the complete sequence of human chromosome 7, its initial designation being C7orf45.[2][3] Human mRNA transcripts were iden...
https://www.wikidoc.org/index.php/SSMEM1