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wikidoc
PARD6A
PARD6A Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene. # Function This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in ...
PARD6A Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene.[1][2][3] # Function This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is in...
https://www.wikidoc.org/index.php/PARD6A
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wikidoc
PCDH15
PCDH15 Protocadherin-15 is a protein that in humans is encoded by the PCDH15 gene. # Function This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. The protein product of this gene consists of a signal peptide, 11 extracel...
PCDH15 Protocadherin-15 is a protein that in humans is encoded by the PCDH15 gene.[1][2][3] # Function This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. The protein product of this gene consists of a signal peptide, 1...
https://www.wikidoc.org/index.php/PCDH15
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wikidoc
PCDHA9
PCDHA9 Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome 5 that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene cl...
PCDHA9 Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene.[1][2] This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome 5 that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor ...
https://www.wikidoc.org/index.php/PCDHA9
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wikidoc
PDCD10
PDCD10 Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. # Function This gene encodes a protein, originally identified in a premyeloid cell line, with similarity to proteins that participate in apoptosis. Three alternative transcripts encoding the same protein, differing only ...
PDCD10 Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene.[1][2] # Function This gene encodes a protein, originally identified in a premyeloid cell line, with similarity to proteins that participate in apoptosis. Three alternative transcripts encoding the same protein, differin...
https://www.wikidoc.org/index.php/PDCD10
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wikidoc
PDE10A
PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene. Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing ...
PDE10A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene.[1][2] Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydro...
https://www.wikidoc.org/index.php/PDE10A
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wikidoc
PDGFRB
PDGFRB Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene. # Gene The PDGFRB gene is located on human chromosome 5 at position q32 (designated as 5q32) and contains 25 exons. The gene is flanked by the genes for granulocyte-macrophage colony-stimulating factor a...
PDGFRB Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene. # Gene The PDGFRB gene is located on human chromosome 5 at position q32 (designated as 5q32) and contains 25 exons. The gene is flanked by the genes for granulocyte-macrophage colony-stimulating factor ...
https://www.wikidoc.org/index.php/PDGFRB
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wikidoc
PDLIM3
PDLIM3 Actin-associated LIM protein (ALP), also known as PDZ and LIM domain protein 3 is a protein that in humans is encoded by the PDLIM3 gene. ALP is highly expressed in cardiac and skeletal muscle, where it localizes to Z-discs and intercalated discs. ALP functions to enhance the crosslinking of actin by alpha actin...
PDLIM3 Actin-associated LIM protein (ALP), also known as PDZ and LIM domain protein 3 is a protein that in humans is encoded by the PDLIM3 gene.[1][2][3] ALP is highly expressed in cardiac and skeletal muscle, where it localizes to Z-discs and intercalated discs. ALP functions to enhance the crosslinking of actin by a...
https://www.wikidoc.org/index.php/PDLIM3
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wikidoc
PEComa
PEComa - Synonyms and keywords:Perivascular epithelioid cell tumor # Overview The World Health Organization defines perivascular epithelioid cell tumors (PEComas) as mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells (PECs). PEComas were first discovered ...
PEComa Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[3] - Synonyms and keywords:Perivascular epithelioid cell tumor # Overview The World Health Organization defines perivascular epithelioid cell tumors (PEComas) as mesenchymal tumors composed o...
https://www.wikidoc.org/index.php/PEComa
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wikidoc
PELP-1
PELP-1 Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) also known as modulator of non-genomic activity of estrogen receptor (MNAR) and transcription factor HMX3 is a protein that in humans is encoded by the PELP1 gene. is a transcriptional corepressor for nuclear receptors such as glucocorticoid receptors a...
PELP-1 Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) also known as modulator of non-genomic activity of estrogen receptor (MNAR) and transcription factor HMX3 is a protein that in humans is encoded by the PELP1 gene.[1] is a transcriptional corepressor for nuclear receptors such as glucocorticoid recepto...
https://www.wikidoc.org/index.php/PELP-1
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wikidoc
PET100
PET100 PET100 homolog is a protein that in humans is encoded by the PET100 gene. Mitochondrial complex IV, or cytochrome c oxidase, is a large transmembrane protein complex that is part of the respiratory electron transport chain of mitochondria. The small protein encoded by the PET100 gene plays a role in the biogenes...
PET100 PET100 homolog is a protein that in humans is encoded by the PET100 gene. Mitochondrial complex IV, or cytochrome c oxidase, is a large transmembrane protein complex that is part of the respiratory electron transport chain of mitochondria. The small protein encoded by the PET100 gene plays a role in the biogene...
https://www.wikidoc.org/index.php/PET100
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wikidoc
PET117
PET117 PET117 homolog is a protein that in humans is encoded by the PET117 gene. Localized to mitochondria, this protein is a chaperone protein involved in the assembly of mitochondrial Complex IV, or Cytochrome C Oxidase. Mutations in this gene can cause Complex IV deficiency with symptoms including medulla oblongata...
PET117 PET117 homolog is a protein that in humans is encoded by the PET117 gene.[1] Localized to mitochondria, this protein is a chaperone protein involved in the assembly of mitochondrial Complex IV, or Cytochrome C Oxidase.[2][3] Mutations in this gene can cause Complex IV deficiency with symptoms including medulla...
https://www.wikidoc.org/index.php/PET117
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wikidoc
PFKFB3
PFKFB3 PFKFB3 is a gene that encodes the 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 enzyme in humans. It is one of 4 tissue-specific PFKFB isoenzymes identified currently (PFKFB1-4). # Gene The PFKFB3 gene is mapped to single locus on chromosome 10 (10p15-p14). It spans a region of 32.5kb with an open readi...
PFKFB3 PFKFB3 is a gene that encodes the 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 enzyme in humans.[1][2][3] It is one of 4 tissue-specific PFKFB isoenzymes identified currently (PFKFB1-4).[4] # Gene The PFKFB3 gene is mapped to single locus on chromosome 10 (10p15-p14).[1][2] It spans a region of 32.5kb...
https://www.wikidoc.org/index.php/PFKFB3
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wikidoc
PFKFB4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 also known as PFKFB4 is an enzyme which in humans is encoded by the PFKFB4 gene. # Function The bifunctional 6-phosphofructo-2-kinase (EC 2.7.1.105)/fructose-2,6-bisphosphatase (EC 3.1.3.46) (PFKFB) regulates the steady-state concentration of fructose 2,6-bi...
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 also known as PFKFB4 is an enzyme which in humans is encoded by the PFKFB4 gene.[1][2] # Function The bifunctional 6-phosphofructo-2-kinase (EC 2.7.1.105)/fructose-2,6-bisphosphatase (EC 3.1.3.46) (PFKFB) regulates the steady-state concentration of fructose...
https://www.wikidoc.org/index.php/PFKFB4
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wikidoc
PGRMC1
PGRMC1 Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as a protein that binds the PGRMC1 protein. The sole ...
PGRMC1 Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary.[1][2] In humans, the PGRMC1 protein is encoded by the PGRMC1 gene.[3] The Sigma-2 receptor was recently identified as a protein that binds the PGRMC1 protein....
https://www.wikidoc.org/index.php/PGRMC1
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wikidoc
PHLDA1
PHLDA1 Pleckstrin homology-like domain family A member 1 (PHLDA1) is a protein that in humans is encoded by the PHLDA1 gene. This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1....
PHLDA1 Pleckstrin homology-like domain family A member 1 (PHLDA1) is a protein that in humans is encoded by the PHLDA1 gene.[1][2][3] This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth...
https://www.wikidoc.org/index.php/PHLDA1
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wikidoc
PHOX2B
PHOX2B Paired-like homeobox 2b (PHOX2B), also known as neuroblastoma Phox (NBPhox), is a protein that in humans is encoded by the PHOX2B gene located on chromosome 4. It codes for a homeodomain transcription factor. It is expressed exclusively in the nervous system, in most neurons that control the viscera (cardiovascu...
PHOX2B Paired-like homeobox 2b (PHOX2B), also known as neuroblastoma Phox (NBPhox), is a protein that in humans is encoded by the PHOX2B gene located on chromosome 4.[1] It codes for a homeodomain transcription factor. It is expressed exclusively in the nervous system, in most neurons that control the viscera (cardiov...
https://www.wikidoc.org/index.php/PHOX2B
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wikidoc
PHYLIP
PHYLIP PHYLIP is a free Computational phylogenetics package of programs for inferring evolutionary trees (phylogenies). The name is an acronym for PHYLogeny Inference Package. It consists of 35 portable programs, i.e. The source code is written in C and precompiled executables are available for Windows (95/98/NT/2000/m...
PHYLIP PHYLIP is a free Computational phylogenetics package of programs for inferring evolutionary trees (phylogenies). The name is an acronym for PHYLogeny Inference Package. It consists of 35 portable programs, i.e. The source code is written in C and precompiled executables are available for Windows (95/98/NT/2000/...
https://www.wikidoc.org/index.php/PHYLIP
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wikidoc
PI4K2A
PI4K2A Phosphatidylinositol 4-kinase 2-alpha is an enzyme that in humans is encoded by the PI4K2A gene. # Classification This gene encodes a phosphatidylinositol 4-kinase which catalyzes phosphorylation of phosphatidylinositol at the D-4 position, yielding phosphatidylinositol 4-phosphate (PI4P). Besides the fact, tha...
PI4K2A Phosphatidylinositol 4-kinase 2-alpha is an enzyme that in humans is encoded by the PI4K2A gene.[1][2][3] # Classification This gene encodes a phosphatidylinositol 4-kinase which catalyzes phosphorylation of phosphatidylinositol at the D-4 position, yielding phosphatidylinositol 4-phosphate (PI4P). Besides the...
https://www.wikidoc.org/index.php/PI4K2A
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wikidoc
PIEZO1
PIEZO1 Piezo1 is a mechanosensitive ion channel protein that in humans is encoded by the gene PIEZO1. Piezo1 and its close homolog piezo2 were cloned in 2010, using an siRNA-based screen for mechanosensitive ion channels. # Structure and function PIEZO1 (this gene) and PIEZO2 share 47% identity with each other and th...
PIEZO1 Piezo1 is a mechanosensitive ion channel protein that in humans is encoded by the gene PIEZO1. Piezo1 and its close homolog piezo2 were cloned in 2010, using an siRNA-based screen for mechanosensitive ion channels.[1] # Structure and function PIEZO1 (this gene) and PIEZO2 share 47% identity with each other an...
https://www.wikidoc.org/index.php/PIEZO1
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wikidoc
PIEZO2
PIEZO2 Piezo-type mechanosensitive ion channel component 2 is a protein that in humans is encoded by the PIEZO2 gene. # Function Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure...
PIEZO2 Piezo-type mechanosensitive ion channel component 2 is a protein that in humans is encoded by the PIEZO2 gene.[1] # Function Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pres...
https://www.wikidoc.org/index.php/PIEZO2
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wikidoc
PIK3R1
PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. # Function Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of...
PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene.[1] # Function Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subuni...
https://www.wikidoc.org/index.php/PIK3R1
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wikidoc
PITRM1
PITRM1 Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene. It is also sometimes called metalloprotease 1 (MP1).PreP facilitates proteostasis by utilizing an ~13300-A(3) catalytic chamber to degrad...
PITRM1 Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene.[1][2][3] It is also sometimes called metalloprotease 1 (MP1).PreP facilitates proteostasis by utilizing an ~13300-A(3) catalytic chamber...
https://www.wikidoc.org/index.php/PITRM1
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wikidoc
PLA2G6
PLA2G6 85 kDa calcium-independent phospholipase A2, also known as 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, or Patatin-like phospholipase domain-containing protein 9 is an enzyme that in humans is encoded by th...
PLA2G6 85 kDa calcium-independent phospholipase A2, also known as 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, or Patatin-like phospholipase domain-containing protein 9 is an enzyme that in humans is encoded by t...
https://www.wikidoc.org/index.php/PLA2G6
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wikidoc
PLAGL2
PLAGL2 Zinc finger protein PLAGL2 is a protein that in humans is encoded by the PLAGL2 gene. Zinc finger protein PLAGL2 is a zinc finger protein that recognizes DNA and/or RNA. The gene has seen in gliomas to suppress cellular differentiation and thus encourage cells to become more stem cell like. Such plasticity is se...
PLAGL2 Zinc finger protein PLAGL2 is a protein that in humans is encoded by the PLAGL2 gene.[1][2][3] Zinc finger protein PLAGL2 is a zinc finger protein that recognizes DNA and/or RNA.[3] The gene has seen in gliomas to suppress cellular differentiation and thus encourage cells to become more stem cell like. Such pla...
https://www.wikidoc.org/index.php/PLAGL2
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wikidoc
PLSCR3
PLSCR3 Phospholipid scramblase 3 is an enzyme that in humans is encoded by the PLSCR3 gene (abbreviated to PLS3 in this section). Like the other phospholipid scramblase family members (PLS1, PLS2, PLS4), PLS3 is a type II plasma membrane protein that is rich in proline and integral in apoptosis, or programmed cell dea...
PLSCR3 Phospholipid scramblase 3 is an enzyme that in humans is encoded by the PLSCR3 gene [1][2] (abbreviated to PLS3 in this section). Like the other phospholipid scramblase family members (PLS1, PLS2, PLS4), PLS3 is a type II plasma membrane protein that is rich in proline and integral in apoptosis, or programmed c...
https://www.wikidoc.org/index.php/PLSCR3
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wikidoc
PLXNA2
PLXNA2 Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of ...
PLXNA2 Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene.[1][2] This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A sub...
https://www.wikidoc.org/index.php/PLXNA2
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wikidoc
PLXNB1
PLXNB1 Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene. # Function Within neural tissues, the plexin family serves as transmembrane receptors for Semaphorins. Outside of neural tissues, Plexin B1 is implicated in the control of cell migration. # Interactions PLXNB1 has been sh...
PLXNB1 Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene.[1][2][3] # Function Within neural tissues, the plexin family serves as transmembrane receptors for Semaphorins.[4] Outside of neural tissues, Plexin B1 is implicated in the control of cell migration.[5] # Interactions PL...
https://www.wikidoc.org/index.php/PLXNB1
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wikidoc
PNPLA3
PNPLA3 Patatin-like phospholipase domain-containing protein 3 (PNPLA3) also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene. # Function Adiponutrin is a triacylglycerol lipase that med...
PNPLA3 Patatin-like phospholipase domain-containing protein 3 (PNPLA3) also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene.[1][2][3] # Function Adiponutrin is a triacylglycerol lipas...
https://www.wikidoc.org/index.php/PNPLA3
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wikidoc
POLR1E
POLR1E DNA-directed RNA polymerase I subunit RPA49 is an enzyme that in humans is encoded by the POLR1E gene. # Model organisms Model organisms have been used in the study of POLR1E function. A conditional knockout mouse line, called Polr1etm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consor...
POLR1E DNA-directed RNA polymerase I subunit RPA49 is an enzyme that in humans is encoded by the POLR1E gene.[1][2] # Model organisms Model organisms have been used in the study of POLR1E function. A conditional knockout mouse line, called Polr1etm1a(KOMP)Wtsi[7][8] was generated as part of the International Knockout...
https://www.wikidoc.org/index.php/POLR1E
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wikidoc
POLR2B
POLR2B DNA-directed RNA polymerase II subunit RPB2 is an enzyme that in humans is encoded by the POLR2B gene. This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subuni...
POLR2B DNA-directed RNA polymerase II subunit RPB2 is an enzyme that in humans is encoded by the POLR2B gene.[1][2] This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase...
https://www.wikidoc.org/index.php/POLR2B
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wikidoc
POLR2E
POLR2E DNA-directed RNA polymerases I, II, and III subunit RPABC1 is a protein that in humans is encoded by the POLR2E gene. This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA...
POLR2E DNA-directed RNA polymerases I, II, and III subunit RPABC1 is a protein that in humans is encoded by the POLR2E gene.[1] This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed...
https://www.wikidoc.org/index.php/POLR2E
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wikidoc
POLR2G
POLR2G DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene. This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, the association of this subunit with the polymerase under s...
POLR2G DNA-directed RNA polymerase II subunit RPB7 is an enzyme that in humans is encoded by the POLR2G gene.[1][2] This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, the association of this subunit with the polymerase ...
https://www.wikidoc.org/index.php/POLR2G
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wikidoc
POLR2H
POLR2H DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene. This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. # Interactions POLR2H has been shown to i...
POLR2H DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene. This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.[1] # Interactions POLR2H has been shown ...
https://www.wikidoc.org/index.php/POLR2H
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wikidoc
POLR2L
POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene. # Function This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines c...
POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene.[1] # Function This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cystein...
https://www.wikidoc.org/index.php/POLR2L
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wikidoc
POLR3E
POLR3E DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene. # Interactions POLR3E has been shown to interact with POLR3D. # Notes and references - ↑ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified hu...
POLR3E DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene.[1][2][3] # Interactions POLR3E has been shown to interact with POLR3D.[4] # Notes and references - ↑ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of un...
https://www.wikidoc.org/index.php/POLR3E
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wikidoc
POLR3F
POLR3F DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the POLR3F gene. # Function The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been s...
POLR3F DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the POLR3F gene.[1][2] # Function The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has...
https://www.wikidoc.org/index.php/POLR3F
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wikidoc
POM121
POM121 Nuclear envelope pore membrane protein POM 121 is a protein that in humans is encoded by the POM121 gene. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. # Function The nuclear envelope creates distinct nuclear...
POM121 Nuclear envelope pore membrane protein POM 121 is a protein that in humans is encoded by the POM121 gene.[1][2][3] Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.[4] # Function The nuclear envelope creates dis...
https://www.wikidoc.org/index.php/POM121
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wikidoc
POPDC2
POPDC2 Popeye domain-containing protein 2 is a protein that in humans is encoded by the POPDC2 gene. # Structure This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle. The P...
POPDC2 Popeye domain-containing protein 2 is a protein that in humans is encoded by the POPDC2 gene.[1][2] # Structure This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle...
https://www.wikidoc.org/index.php/POPDC2
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wikidoc
POU3F2
POU3F2 POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene. # Function N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as th...
POU3F2 POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene.[1][2] # Function N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred t...
https://www.wikidoc.org/index.php/POU3F2
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wikidoc
POU3F4
POU3F4 POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome. POU3F4 is involved in the patterning of the neural tube and both the paraventricular and supraoptic nuclei of the hypothalamus in the developing embryo. During development, POU3F4 is a...
POU3F4 POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome.[1][2][3] POU3F4 is involved in the patterning of the neural tube and both the paraventricular and supraoptic nuclei of the hypothalamus in the developing embryo.[4] During development...
https://www.wikidoc.org/index.php/POU3F4
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wikidoc
POU4F1
POU4F1 POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed...
POU4F1 POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene.[1][2] BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly ex...
https://www.wikidoc.org/index.php/POU4F1
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wikidoc
PPAP2B
PPAP2B Lipid phosphate phosphohydrolase 3 (LPP3), also known as phospholipid phosphatase 3 (PLPP3) and phosphatidic acid phosphatase type 2B (PAP-2b or PPAP2B), is an enzyme that in humans is encoded by the PPAP2B gene on chromosome 1. It is ubiquitously expressed in many tissues and cell types. LPP3 is a cell-surface ...
PPAP2B Lipid phosphate phosphohydrolase 3 (LPP3), also known as phospholipid phosphatase 3 (PLPP3) and phosphatidic acid phosphatase type 2B (PAP-2b or PPAP2B), is an enzyme that in humans is encoded by the PPAP2B gene on chromosome 1.[1][2][3] It is ubiquitously expressed in many tissues and cell types.[4] LPP3 is a ...
https://www.wikidoc.org/index.php/PPAP2B
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wikidoc
PPP1CA
PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene. # Function The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involv...
PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene. # Function The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be invol...
https://www.wikidoc.org/index.php/PPP1CA
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wikidoc
PPP1CB
PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit is an enzyme that in humans is encoded by the PPP1CB gene. The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the reg...
PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit is an enzyme that in humans is encoded by the PPP1CB gene.[1] The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the...
https://www.wikidoc.org/index.php/PPP1CB
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wikidoc
PPP1R8
PPP1R8 Nuclear inhibitor of protein phosphatase 1 is an enzyme that in humans is encoded by the PPP1R8 gene. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind bu...
PPP1R8 Nuclear inhibitor of protein phosphatase 1 is an enzyme that in humans is encoded by the PPP1R8 gene.[1][2][3] This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and c...
https://www.wikidoc.org/index.php/PPP1R8
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wikidoc
PPP2CB
PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform is an enzyme that in humans is encoded by the PPP2CB gene. # Function This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control ...
PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform is an enzyme that in humans is encoded by the PPP2CB gene.[1] # Function This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative cont...
https://www.wikidoc.org/index.php/PPP2CB
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wikidoc
PPP2R4
PPP2R4 Serine/threonine-protein phosphatase 2A regulatory subunit B' is an enzyme that in humans is encoded by the PPP2R4 gene. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeri...
PPP2R4 Serine/threonine-protein phosphatase 2A regulatory subunit B' is an enzyme that in humans is encoded by the PPP2R4 gene.[1][2] Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are hetero...
https://www.wikidoc.org/index.php/PPP2R4
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wikidoc
PRDM12
PRDM12 PR domain zinc finger protein 12 is a protein that in humans is encoded by the PRDM12 gene. This gene is normally switched on during the development of pain-sensing nerve cells. People with homozygous mutations of the PRDM12 gene experience congenital insensitivity to pain (CIP). PRMD12 is a part of a larger do...
PRDM12 PR domain zinc finger protein 12 is a protein that in humans is encoded by the PRDM12 gene. This gene is normally switched on during the development of pain-sensing nerve cells. People with homozygous mutations of the PRDM12 gene experience congenital insensitivity to pain (CIP).[1][2] PRMD12 is a part of a la...
https://www.wikidoc.org/index.php/PRDM12
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wikidoc
PRDM16
PRDM16 PR domain containing 16, also known as PRDM16, is a protein which in humans is encoded by the PRDM16 gene. PRDM16 acts as a transcription coregulator that controls the development of brown adipocytes in brown adipose tissue. Previously, this coregulator was believed to be present only in brown adipose tissue, ...
PRDM16 PR domain containing 16, also known as PRDM16, is a protein which in humans is encoded by the PRDM16 gene.[1][2] PRDM16 acts as a transcription coregulator that controls the development of brown adipocytes in brown adipose tissue.[3] Previously, this coregulator was believed to be present only in brown adipos...
https://www.wikidoc.org/index.php/PRDM16
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wikidoc
PRIMA1
PRIMA1 Proline-rich membrane anchor 1, also known as PRiMA, is a protein that in humans is encoded by the PRIMA1 gene. # Function PRiMA functions to organize acetylcholinesterase (AChE) into tetramers, and to anchor AChE at neural cell membranes. This is accomplished by the proline rich anchor domain (PRAD) of PRIMA1 ...
PRIMA1 Proline-rich membrane anchor 1, also known as PRiMA, is a protein that in humans is encoded by the PRIMA1 gene.[1][2] # Function PRiMA functions to organize acetylcholinesterase (AChE) into tetramers, and to anchor AChE at neural cell membranes.[1] This is accomplished by the proline rich anchor domain (PRAD) ...
https://www.wikidoc.org/index.php/PRIMA1
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wikidoc
PRKAB1
PRKAB1 5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits...
PRKAB1 5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene.[1][2] The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma s...
https://www.wikidoc.org/index.php/PRKAB1
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wikidoc
PRKAB2
PRKAB2 5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits...
PRKAB2 5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene.[1][2] The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma s...
https://www.wikidoc.org/index.php/PRKAB2
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wikidoc
PRKACA
PRKACA The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene. This enzyme is responsible for phosphorylating other proteins and substrates, changing their activity. Protein kinase A catalytic subunit (PKA Cα) is a member of the AGC kinase family (protein kin...
PRKACA The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene.[1] This enzyme is responsible for phosphorylating other proteins and substrates, changing their activity. Protein kinase A catalytic subunit (PKA Cα) is a member of the AGC kinase family (protein...
https://www.wikidoc.org/index.php/PRKACA
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wikidoc
PRKACB
PRKACB cAMP-dependent protein kinase catalytic subunit beta is an enzyme that in humans is encoded by the PRKACB gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the protein kinase A (PKA), which transduces the signal through phosphorylation of diff...
PRKACB cAMP-dependent protein kinase catalytic subunit beta is an enzyme that in humans is encoded by the PRKACB gene.[1] cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the protein kinase A (PKA), which transduces the signal through phosphorylation of ...
https://www.wikidoc.org/index.php/PRKACB
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wikidoc
PRKCB1
PRKCB1 Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and ar...
PRKCB1 Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene.[1] Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets an...
https://www.wikidoc.org/index.php/PRKCB1
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wikidoc
PRPF31
PRPF31 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. # Function PRPF31 is the gene coding for the splicing factor hPRP31. It is essential for the formation of the spliceosome hPRP31 is associated with the U4/U6 di-snRNP an...
PRPF31 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene.[1] # Function PRPF31 is the gene coding for the splicing factor hPRP31. It is essential for the formation of the spliceosome hPRP31 is associated with the U4/U6 di-snRN...
https://www.wikidoc.org/index.php/PRPF31
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wikidoc
PRSS56
PRSS56 Putative serine protease 56 (PRSS56) is a serine protease that has been implicated in human eye development. # Genomics The gene is located on long arm of chromosome 2 (2q37.1). The encoded protein is 603 amino acid residues in length with a predicted molecular weight of 64 597 Daltons. The protein contains a p...
PRSS56 Putative serine protease 56 (PRSS56) is a serine protease that has been implicated in human eye development. # Genomics The gene is located on long arm of chromosome 2 (2q37.1). The encoded protein is 603 amino acid residues in length with a predicted molecular weight of 64 597 Daltons. The protein contains a ...
https://www.wikidoc.org/index.php/PRSS56
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wikidoc
PSMB10
PSMB10 Proteasome subunit beta type-10 as known as 20S proteasome subunit beta-2i is a protein that in humans is encoded by the PSMB10 gene. This protein has a major role in the immune system as part of an immunoproteasome that is primarily induced upon infection and formed by replacing constitutive beta subunits with ...
PSMB10 Proteasome subunit beta type-10 as known as 20S proteasome subunit beta-2i is a protein that in humans is encoded by the PSMB10 gene.[1] This protein has a major role in the immune system as part of an immunoproteasome that is primarily induced upon infection and formed by replacing constitutive beta subunits w...
https://www.wikidoc.org/index.php/PSMB10
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wikidoc
PSMD10
PSMD10 26S proteasome non-ATPase regulatory subunit 10 or gankyrin is an enzyme that in humans is encoded by the PSMD10 gene. Gankyrin is an oncoprotein that is a component of the 19S regulatory cap of the proteasome. Structurally, it contains a 33-amino acid ankyrin repeat that forms a series of alpha helices. It play...
PSMD10 26S proteasome non-ATPase regulatory subunit 10 or gankyrin is an enzyme that in humans is encoded by the PSMD10 gene.[1] Gankyrin is an oncoprotein that is a component of the 19S regulatory cap of the proteasome. Structurally, it contains a 33-amino acid ankyrin repeat that forms a series of alpha helices.[2] ...
https://www.wikidoc.org/index.php/PSMD10
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wikidoc
PSMD11
PSMD11 26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-i...
PSMD11 26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene.[1][2][3] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings o...
https://www.wikidoc.org/index.php/PSMD11
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wikidoc
PSMD12
PSMD12 26S proteasome non-ATPase regulatory subunit 12 is an enzyme that in humans is encoded by the PSMD12 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-i...
PSMD12 26S proteasome non-ATPase regulatory subunit 12 is an enzyme that in humans is encoded by the PSMD12 gene.[1] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 n...
https://www.wikidoc.org/index.php/PSMD12
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wikidoc
PSMD13
PSMD13 26S proteasome non-ATPase regulatory subunit 13 is an enzyme that in humans is encoded by the PSMD13 gene. # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-i...
PSMD13 26S proteasome non-ATPase regulatory subunit 13 is an enzyme that in humans is encoded by the PSMD13 gene.[1][2] # Function The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 2...
https://www.wikidoc.org/index.php/PSMD13
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wikidoc
PSMD14
PSMD14 26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene. This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex. Nine subunits Rpn3, Rpn5, Rpn6, Rpn7, Rpn8, Rpn9, Rpn...
PSMD14 26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene.[1][2] This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex.[3] Nine subunits Rpn3, Rpn5, Rpn6, Rpn7, Rpn8,...
https://www.wikidoc.org/index.php/PSMD14
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wikidoc
PTPN11
PTPN11 Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), SHP-2, or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase (PTP) Shp2. PTPN11 is a member of the protein t...
PTPN11 Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), SHP-2, or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase (PTP) Shp2.[1][2] PTPN11 is a member of the pr...
https://www.wikidoc.org/index.php/PTPN11
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wikidoc
PTPN12
PTPN12 Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,...
PTPN12 Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.[1][2] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell ...
https://www.wikidoc.org/index.php/PTPN12
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wikidoc
PTPN22
PTPN22 Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the PTPN22 gene. This gene can be expressed in different forms. PTPN22 affects the responsiveness of T and B cell receptors, and mutations are associated with increases or decreases in r...
PTPN22 Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the PTPN22 gene.[1][2][3] This gene can be expressed in different forms. PTPN22 affects the responsiveness of T and B cell receptors, and mutations are associated with increases or decr...
https://www.wikidoc.org/index.php/PTPN22
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wikidoc
PTPRN2
PTPRN2 Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) also known as islet cell autoantigen-related protein (ICAAR) and phogrin is an enzyme that in humans is encoded by the PTPRN2 gene. PTPRN and PTPRN2 (this gene) are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. #...
PTPRN2 Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) also known as islet cell autoantigen-related protein (ICAAR) and phogrin is an enzyme that in humans is encoded by the PTPRN2 gene.[1][2][3] PTPRN and PTPRN2 (this gene) are both found to be major autoantigens associated with insulin-dependent diabetes me...
https://www.wikidoc.org/index.php/PTPRN2
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wikidoc
PTPRZ1
PTPRZ1 Receptor-type tyrosine-protein phosphatase zeta also known as phosphacan is an enzyme that in humans is encoded by the PTPRZ1 gene. # Function This gene is a member of the receptor tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein phosphatase dom...
PTPRZ1 Receptor-type tyrosine-protein phosphatase zeta also known as phosphacan is an enzyme that in humans is encoded by the PTPRZ1 gene.[1][2][3] # Function This gene is a member of the receptor tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein phosp...
https://www.wikidoc.org/index.php/PTPRZ1
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wikidoc
PYCARD
PYCARD PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene. It is localized mainly in the nucleus of monocytes and macrophages. In case of pathogen infection, however, it relocalizes rapidly to the cytoplasm, perinuclear...
PYCARD PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene.[1] It is localized mainly in the nucleus of monocytes and macrophages. In case of pathogen infection, however, it relocalizes rapidly to the cytoplasm, perinuc...
https://www.wikidoc.org/index.php/PYCARD
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wikidoc
Palate
Palate # Overview The palate (Template:IPAEng) is the roof of the mouth in humans and vertebrate animals. It separates the oral cavity from the nasal cavity. The palate is divided into two parts, the anterior bony hard palate, and the posterior fleshy soft palate or velum. The maxillary nerve branch of the trigeminal ...
Palate Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The palate (Template:IPAEng) is the roof of the mouth in humans and vertebrate animals. It separates the oral cavity from the nasal cavity. The palate is divided into two parts, the anterior bony hard palate, and the posteri...
https://www.wikidoc.org/index.php/Palate
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wikidoc
Pannus
Pannus Pannus is a medical term for a hanging flap of tissue. When involving the stomach, it is called a Panniculus and consists of skin, fat, and sometimes contents of the internal abdomen as part of a hernia. A pannus can be the result of loose hanging tissues after pregnancy or weight loss. It can also be the defor...
Pannus Pannus is a medical term for a hanging flap of tissue. When involving the stomach, it is called a Panniculus and consists of skin, fat, and sometimes contents of the internal abdomen as part of a hernia. A pannus can be the result of loose hanging tissues after pregnancy or weight loss. It can also be the defo...
https://www.wikidoc.org/index.php/Pannus
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wikidoc
Papain
Papain Papain is a cysteine protease (EC 3.4.22.2) hydrolase enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). # Structure It consists of 212 amino acids stabilised by 3 disulfide bridges. Its 3D structure consists of 2 distinct structural domains with a cleft between them. ...
Papain Papain is a cysteine protease (EC 3.4.22.2) hydrolase enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). # Structure It consists of 212[1] amino acids stabilised by 3 disulfide bridges. Its 3D structure consists of 2 distinct structural domains with a cleft between th...
https://www.wikidoc.org/index.php/Papain
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wikidoc
Papaya
Papaya The papaya (from Carib via Spanish), is the fruit of the tree Carica papaya, in the genus Carica. It is native to the tropics of the Americas, and was cultivated in Mexico several centuries before the emergence of the Mesoamerican classic cultures. Nowadays, the papaya is also known as fruta bomba (Cuba), lecho...
Papaya The papaya (from Carib via Spanish), is the fruit of the tree Carica papaya, in the genus Carica. It is native to the tropics of the Americas, and was cultivated in Mexico several centuries before the emergence of the Mesoamerican classic cultures. Nowadays, the papaya is also known as fruta bomba (Cuba), lech...
https://www.wikidoc.org/index.php/Papaya
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wikidoc
Papule
Papule A papule is a small, solid and usually conical elevation of the skin. Papules do not contain pus, which distinguishes them from pustules. Papules often occur in clusters and can accompany rashes. A condition that causes a papule is called a "Papulosis". Examples of papuloses include: - Lymphomatoid papulosis - B...
Papule A papule is a small, solid and usually conical elevation of the skin. Papules do not contain pus, which distinguishes them from pustules. Papules often occur in clusters and can accompany rashes. A condition that causes a papule is called a "Papulosis". Examples of papuloses include: - Lymphomatoid papulosis - ...
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Patent
Patent A patent is a set of exclusive rights granted by a state to an inventor or his assignee for a fixed period of time in exchange for a disclosure of an invention. The procedure for granting patents, the requirements placed on the patentee and the extent of the exclusive rights vary widely between countries accordi...
Patent A patent is a set of exclusive rights granted by a state to an inventor or his assignee for a fixed period of time in exchange for a disclosure of an invention. The procedure for granting patents, the requirements placed on the patentee and the extent of the exclusive rights vary widely between countries accord...
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Pawpaw
Pawpaw # Overview Pawpaw (Asimina) is a genus of eight or nine species of small trees with large leaves and fruit, native to eastern North America. The genus includes the largest edible fruit indigenous to the continent. They are understory trees found in deep fertile bottomland and hilly upland habitat. Pawpaw is in ...
Pawpaw # Overview Pawpaw (Asimina) is a genus of eight or nine species of small trees with large leaves and fruit, native to eastern North America. The genus includes the largest edible fruit indigenous to the continent. They are understory trees found in deep fertile bottomland and hilly upland habitat. Pawpaw is in ...
https://www.wikidoc.org/index.php/Pawpaw
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Pectin
Pectin # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug p...
Pectin Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an ed...
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Pedant
Pedant A pedant, or pædant, is a person who is overly concerned with formalism and precision, or who makes a show of learning. The corresponding (obsolete) female noun is pedantess. The term comes from the French pédant (1566 in Darme & Hatzfeldster's Dictionnaire général de la langue française) or its source Italian p...
Pedant A pedant, or pædant, is a person who is overly concerned with formalism and precision, or who makes a show of learning. The corresponding (obsolete) female noun is pedantess. The term comes from the French pédant (1566 in Darme & Hatzfeldster's Dictionnaire général de la langue française) or its source Italian ...
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Pepsin
Pepsin Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease). It is produced in the stomach and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin has a three-dimensional structure,...
Pepsin Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease). It is produced in the stomach and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin has a three-dimensional structure...
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Peptic
Peptic # Overview Peptic is an adjective that refers to any part of the body that normally has an acidic lumen. 'Peptic' is medical and veterinary terminology, most often used in the context of humans. # Peptic anatomy The peptic areas of the human body under normal circumstances are the stomach and duodenum. A perso...
Peptic # Overview Peptic is an adjective that refers to any part of the body that normally has an acidic lumen. 'Peptic' is medical and veterinary terminology, most often used in the context of humans. # Peptic anatomy The peptic areas of the human body under normal circumstances are the stomach and duodenum. A perso...
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Rectum
Rectum # Overview The rectum (from the Latin rectum intestinum, meaning straight intestine) is the final straight portion of the large intestine in some mammals, and the gut in others, terminating in the anus. The human rectum is about 12 cm long. At its commencement its caliber is similar to that of the sigmoid colon...
Rectum Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Template:Infobox Anatomy The rectum (from the Latin rectum intestinum, meaning straight intestine) is the final straight portion of the large intestine in some mammals, and the gut in others, terminating in the anus. The human rectum is about 12 cm ...
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Persin
Persin Persin is a fungicidal toxin present in the avocado, isolated only recently. It is generally harmless to humans, but when consumed by domestic animals in large quantities it is dangerous. It has been suggested as a treatment for breast cancer. The chemistry of persin is not yet understood, but it is similar to a...
Persin Persin is a fungicidal toxin present in the avocado, isolated only recently.[1] It is generally harmless to humans, but when consumed by domestic animals in large quantities it is dangerous. It has been suggested as a treatment for breast cancer.[2] The chemistry of persin is not yet understood, but it is simil...
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Person
Person The classical definition of a person is "a human being regarded as an individual." In modern usage, the term "person" is subject to dispute and re-interpretation based on alternate definitions. This is especially so for uses that are not necessarily synonymous with the classical definition of human or human bei...
Person The classical definition of a person is "a human being regarded as an individual."[1] In modern usage, the term "person" is subject to dispute and re-interpretation based on alternate definitions. This is especially so for uses that are not necessarily synonymous with the classical definition of human or human...
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Peyote
Peyote Lophophora williamsii, (lō-fof′ŏ-ră wil-yăm′sē-ī), better known by its common name Peyote, but also sometimes called Mescal Button or the Divine Cactus, is a small, spineless cactus whose native region extends from the southwestern United States, specifically in the southwestern part of Texas, through central Me...
Peyote Template:ConvertIPA Lophophora williamsii, (lō-fof′ŏ-ră wil-yăm′sē-ī), better known by its common name Peyote, but also sometimes called Mescal Button or the Divine Cactus, is a small, spineless cactus whose native region extends from the southwestern United States, specifically in the southwestern part of Texa...
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Phlegm
Phlegm Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic...
Phlegm Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire t...
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Piedra
Piedra Piedra is a hair disease caused by a fungus. Types include: - White piedra - Black piedra # Gallery - Under a relatively-low magnification of 100X, this photomicrograph reveals some of the pathologic morphology displayed by a primate hair shaft indicative of the disease known as, “black piedra”, also known as “...
Piedra Piedra is a hair disease caused by a fungus.[1] Types include: - White piedra - Black piedra # Gallery - Under a relatively-low magnification of 100X, this photomicrograph reveals some of the pathologic morphology displayed by a primate hair shaft indicative of the disease known as, “black piedra”, also known ...
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Pilosa
Pilosa Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic...
Pilosa Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire t...
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Piping
Piping Within industry, piping is a system of pipes used to convey fluids and gases, from one location to another. The engineering discipline of piping design studies the best and most efficient manner of transporting fluid to where it is needed. Industrial process piping (and accompanying in-line components) can be ma...
Piping Within industry, piping is a system of pipes used to convey fluids and gases, from one location to another. The engineering discipline of piping design studies the best and most efficient manner of transporting fluid to where it is needed.[1][2] Industrial process piping (and accompanying in-line components) ca...
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Plexus
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Plexus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in s...
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Potash
Potash Potash (or carbonate of potash) is an impure form of potassium carbonate (K2CO3). Potash has been used since antiquity in the manufacture of glass and soap and as a fertilizer. The name comes from the English words pot and ash, referring to its discovery in the water-soluble fraction of wood ash. The term has b...
Potash Potash (or carbonate of potash) is an impure form of potassium carbonate (K2CO3). Potash has been used since antiquity in the manufacture of glass and soap and as a fertilizer. The name comes from the English words pot and ash, referring to its discovery in the water-soluble fraction of wood ash. The term has ...
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Potato
Potato The potato is the term which applies either to the starchy tuberous crop from the perennial plant Solanum tuberosum of the Solanaceae, or nightshade, family, or to the plant itself. They are the world's most widely grown tuber crop, and the fourth largest food crop in terms of fresh produce — after rice, wheat, ...
Potato The potato is the term which applies either to the starchy tuberous crop from the perennial plant Solanum tuberosum of the Solanaceae, or nightshade, family, or to the plant itself. They are the world's most widely grown tuber crop, and the fourth largest food crop in terms of fresh produce — after rice, wheat,...
https://www.wikidoc.org/index.php/Potato
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Probit
Probit In probability theory and statistics, the probit function is the inverse cumulative distribution function (CDF), or quantile function associated with the standard normal distribution. It has applications in exploratory statistical graphics and specialized regression modeling of binary response variables. For th...
Probit In probability theory and statistics, the probit function is the inverse cumulative distribution function (CDF), or quantile function associated with the standard normal distribution. It has applications in exploratory statistical graphics and specialized regression modeling of binary response variables. For t...
https://www.wikidoc.org/index.php/Probit
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Proton
Proton Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic...
Proton Template:Infobox Particle Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Edito...
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Pulsus
Pulsus Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic...
Pulsus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in s...
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Purell
Purell Purell is an instant hand sanitizer which claims to kill "99.99% of most common germs that may cause illness in as little as 15 seconds." Its active ingredient is ethyl alcohol (62%). It is used by wetting one's hands thoroughly with the product, then briskly rubbing one's hands together until dry. Purell is th...
Purell Purell is an instant hand sanitizer which claims to kill "99.99% of most common germs that may cause illness in as little as 15 seconds." Its active ingredient is ethyl alcohol (62%). It is used by wetting one's hands thoroughly with the product, then briskly rubbing one's hands together until dry. Purell is t...
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Pyemia
Pyemia Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entire topic...
Pyemia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in s...
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QRICH1
QRICH1 QRICH1, also known as Glutamine-rich protein 1, is a protein that in humans is encoded by the QRICH1 gene. One notable feature of this protein is that it contains a Caspase Activation Recruitment Domain, also known as a CARD domain. As a result of having this domain, QRICH1 is believed to be involved in apoptoti...
QRICH1 QRICH1, also known as Glutamine-rich protein 1, is a protein that in humans is encoded by the QRICH1 gene.[1] One notable feature of this protein is that it contains a Caspase Activation Recruitment Domain, also known as a CARD domain.[2] As a result of having this domain, QRICH1 is believed to be involved in a...
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QRICH2
QRICH2 Glutamine-rich protein 2 is a protein that in humans is edcoded by the QRICH2 gene on human chromosome 17. The function of QRICH2 protein is mostly unknown, but it has been shown that QRICH2 gene contains a high molecular weight Glutenin domain and an ATPase involved domain. QRICH2 gene is highly expressed in te...
QRICH2 Glutamine-rich protein 2 is a protein that in humans is edcoded by the QRICH2 gene on human chromosome 17.[1][2] The function of QRICH2 protein is mostly unknown, but it has been shown that QRICH2 gene contains a high molecular weight Glutenin domain and an ATPase involved domain.[2] QRICH2 gene is highly expre...
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Quartz
Quartz Quartz (from German Template:Audio) is the most abundant mineral in the Earth's continental crust (although feldspar is more common in the world as a whole). It is made up of a lattice of silica (Template:SiliconTemplate:Oxygen) tetrahedra. Quartz has a hardness of 7 on the Mohs scale and a density of 2.65 g/cm...
Quartz Template:Infobox mineral Quartz (from German Template:Audio[1]) is the most abundant mineral in the Earth's continental crust (although feldspar is more common in the world as a whole). It is made up of a lattice of silica (Template:SiliconTemplate:Oxygen) tetrahedra. Quartz has a hardness of 7 on the Mohs sca...
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Quench
Quench # Overview A quench refers to a rapid cooling. In polymer chemistry and materials science, quenching is used to prevent low-temperature processes such as phase transformations from occurring by only providing a narrow window of time in which the reaction is both thermodynamically favorable and kinetically acces...
Quench # Overview A quench refers to a rapid cooling. In polymer chemistry and materials science, quenching is used to prevent low-temperature processes such as phase transformations from occurring by only providing a narrow window of time in which the reaction is both thermodynamically favorable and kinetically acces...
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