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TP63
TP63 Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 (also known as the p63) gene. The TP63 gene was discovered 20 years after the discovery of the p53 tumor suppressor gene and along with p73 constitutes the p53 gene f...
TP63 Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 (also known as the p63) gene.[1][2][3][4] The TP63 gene was discovered 20 years after the discovery of the p53 tumor suppressor gene and along with p73 constitutes t...
https://www.wikidoc.org/index.php/TP63
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TPBG
TPBG Trophoblast glycoprotein, also known as TPBG, 5T4, Wnt-Activated Inhibitory Factor 1 or WAIF1, is a human protein encoded by a TPBG gene. TPBG is an antagonist of Wnt/β-catenin signalling pathway. # Clinical significance 5T4 is an antigen expressed in a number of carcinomas. It is an N-glycosylated transmembrane ...
TPBG Trophoblast glycoprotein, also known as TPBG, 5T4, Wnt-Activated Inhibitory Factor 1 or WAIF1, is a human protein encoded by a TPBG gene.[1] TPBG is an antagonist of Wnt/β-catenin signalling pathway.[2] # Clinical significance 5T4 is an antigen expressed in a number of carcinomas.[3] It is an N-glycosylated tran...
https://www.wikidoc.org/index.php/TPBG
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wikidoc
TPH1
TPH1 Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. TPH1 was first discovered to synthesize serotonin in 1988 and was thought that there only was a single TPH gene until 2003, while a second form was found in the mouse (Tph2), rat and human brain (...
TPH1 Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene.[1] TPH1 was first discovered to synthesize serotonin in 1988[2] and was thought that there only was a single TPH gene until 2003, while a second form was found in the mouse (Tph2), rat and human ...
https://www.wikidoc.org/index.php/TPH1
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wikidoc
TPI1
TPI1 Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this ge...
TPI1 Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this g...
https://www.wikidoc.org/index.php/TPI1
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wikidoc
TPM1
TPM1 Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene. This gene is a member of the tropomyosin (Tm) family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. # Struc...
TPM1 Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene.[1] This gene is a member of the tropomyosin (Tm) family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. # S...
https://www.wikidoc.org/index.php/TPM1
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wikidoc
TPM2
TPM2 β-Tropomyosin, also known as tropomyosin beta chain is a protein that in humans is encoded by the TPM2 gene. β-tropomyosin is striated muscle-specific coiled coil dimer that functions to stabilize actin filaments and regulate muscle contraction. # Structure β-tropomyosin is roughly 32 kDa in molecular weight (284...
TPM2 β-Tropomyosin, also known as tropomyosin beta chain is a protein that in humans is encoded by the TPM2 gene.[1][2] β-tropomyosin is striated muscle-specific coiled coil dimer that functions to stabilize actin filaments and regulate muscle contraction. # Structure β-tropomyosin is roughly 32 kDa in molecular weig...
https://www.wikidoc.org/index.php/TPM2
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TPX2
TPX2 Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene. It is one of the many spindle assembly factors that play a key role in inducing microtubule assembly and growth during M phase. # Key domains of TPX2 TPX2 has been reported to have two NLS-containing domains that mediate its loc...
TPX2 Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene. [1][2][3] It is one of the many spindle assembly factors that play a key role in inducing microtubule assembly and growth during M phase. # Key domains of TPX2 TPX2 has been reported to have two NLS-containing domains that media...
https://www.wikidoc.org/index.php/TPX2
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TRIF
TRIF TIR-domain-containing adapter-inducing interferon-β (TRIF) is an adapter in responding to activation of toll-like receptors (TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter. Toll-like receptors (TLRs) recognize specific c...
TRIF TIR-domain-containing adapter-inducing interferon-β (TRIF) is an adapter in responding to activation of toll-like receptors (TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter.[1] Toll-like receptors (TLRs) recognize specif...
https://www.wikidoc.org/index.php/TRIF
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TSC2
TSC2 Tuberous Sclerosis Complex 2 (TSC2), also known as Tuberin, is a protein that in humans is encoded by the TSC2 gene. # Function Mutations in this gene lead to tuberous sclerosis. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. Hamartin coded by the gene TSC1 functi...
TSC2 Tuberous Sclerosis Complex 2 (TSC2), also known as Tuberin, is a protein that in humans is encoded by the TSC2 gene. # Function Mutations in this gene lead to tuberous sclerosis. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. Hamartin coded by the gene TSC1 funct...
https://www.wikidoc.org/index.php/TSC2
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wikidoc
TTC8
TTC8 Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene. # Function TTC8 is associated with gamma-tubulin, BBS4, and PCM1 in the centrosome. PCM1 in turn is involved in centriolar replication during ciliogenesis. TTC8 is located in th...
TTC8 Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene.[1] # Function TTC8 is associated with gamma-tubulin, BBS4, and PCM1 in the centrosome.[1] PCM1 in turn is involved in centriolar replication during ciliogenesis.[2] TTC8 is loc...
https://www.wikidoc.org/index.php/TTC8
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wikidoc
TWF1
TWF1 Twinfilin-1 is a protein that in humans is encoded by the TWF1 gene. This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich struc...
TWF1 Twinfilin-1 is a protein that in humans is encoded by the TWF1 gene.[1][2] This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-ric...
https://www.wikidoc.org/index.php/TWF1
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TXN2
TXN2 Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the re...
TXN2 Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22.[1][2][3] This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles...
https://www.wikidoc.org/index.php/TXN2
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Taho
Taho Tahô is a Philippine snack food made of fresh soft/silken tofu, arnibal (brown sugar syrup), and sago "pearls" (similar to tapioca pearls). This staple comfort food is a signature sweet and can be found all over the country. # History The history of taho is debatable, but early records suggest it may trace its or...
Taho Tahô is a Philippine snack food made of fresh soft/silken tofu, arnibal (brown sugar syrup), and sago "pearls" (similar to tapioca pearls).[1] This staple comfort food is a signature sweet and can be found all over the country. # History The history of taho is debatable, but early records suggest it may trace it...
https://www.wikidoc.org/index.php/Taho
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wikidoc
Watt
Watt The watt (symbol: W) is the SI derived unit of power, equal to one joule of energy per second. It measures a rate of energy use or production. A human climbing a flight of stairs is doing work at a rate of about 200 watts. A typical automobile engine produces mechanical energy at a rate of 25,000 watts (approxima...
Watt The watt (symbol: W) is the SI derived unit of power, equal to one joule of energy per second. It measures a rate of energy use or production. A human climbing a flight of stairs is doing work at a rate of about 200 watts. A typical automobile engine produces mechanical energy at a rate of 25,000 watts (approxim...
https://www.wikidoc.org/index.php/Terawatt
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wikidoc
Test
Test # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pag...
Test Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare d...
https://www.wikidoc.org/index.php/Test
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wikidoc
Tick
Tick Tick is the common name for the small arachnids that, along with other mites, constitute the order Acarina. Ticks are ectoparasites (external parasites), living by hematophagy on the blood of mammals, birds, and occasionally reptiles and amphibians. Ticks are important vectors of a number of diseases, including L...
Tick Template:Wikispecies Tick is the common name for the small arachnids that, along with other mites, constitute the order Acarina. Ticks are ectoparasites (external parasites), living by hematophagy on the blood of mammals, birds, and occasionally reptiles and amphibians. Ticks are important vectors of a number of...
https://www.wikidoc.org/index.php/Tick
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wikidoc
Tsix
Tsix Tsix is a non-coding RNA gene that is antisense to the Xist RNA. Tsix binds Xist during X chromosome inactivation. The name Tsix comes from the reverse of Xist, which stands for X-inactive specific transcript. # Background Female mammals have two X chromosomes and males have one X and one Y chromosome. The X chro...
Tsix Tsix is a non-coding RNA gene that is antisense to the Xist RNA. Tsix binds Xist during X chromosome inactivation. The name Tsix comes from the reverse of Xist, which stands for X-inactive specific transcript.[1] # Background Female mammals have two X chromosomes and males have one X and one Y chromosome. The X ...
https://www.wikidoc.org/index.php/Tsix
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wikidoc
UBA1
UBA1 Ubiquitin-like modifier activating enzyme 1 (UBA1) is an enzyme which in humans is encoded by the UBA1 gene. UBA1 participates in ubiquitination and the NEDD8 pathway for protein folding and degradation, among many other biological processes. This protein has been linked to X-linked spinal muscular atrophy type 2,...
UBA1 Ubiquitin-like modifier activating enzyme 1 (UBA1) is an enzyme which in humans is encoded by the UBA1 gene.[1][2] UBA1 participates in ubiquitination and the NEDD8 pathway for protein folding and degradation, among many other biological processes.[1][3] This protein has been linked to X-linked spinal muscular at...
https://www.wikidoc.org/index.php/UBA1
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wikidoc
UBA2
UBA2 Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene. Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellu...
UBA2 Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene.[1] Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intrac...
https://www.wikidoc.org/index.php/UBA2
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wikidoc
UBL5
UBL5 Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene. It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans. Ubiquitin-like protein...
UBL5 Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.[1] It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.[2] Ubiquitin-like ...
https://www.wikidoc.org/index.php/UBL5
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wikidoc
UCK2
UCK2 Uridine-cytidine kinase 2 (UCK2) is an enzyme that in humans is encoded by the UCK2 gene. The protein encoded by this gene catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. This is the first step in the production of the pyrimidine ...
UCK2 Uridine-cytidine kinase 2 (UCK2) is an enzyme that in humans is encoded by the UCK2 gene.[1] The protein encoded by this gene catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. This is the first step in the production of the pyrimid...
https://www.wikidoc.org/index.php/UCK2
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wikidoc
UCP3
UCP3 Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. UCP3 is a mitochondrial uncoupling protein 3, which is encoded by UCP3. The gene is located in chromosome (11q13.4) with an exon count of 7 (HGNC et al., 2016). Uncoupling protein being a supreme family of mitochondrial ani...
UCP3 Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene.[1][2] UCP3 is a mitochondrial uncoupling protein 3, which is encoded by UCP3. The gene is located in chromosome (11q13.4) with an exon count of 7 (HGNC et al., 2016). Uncoupling protein being a supreme family of mitochondr...
https://www.wikidoc.org/index.php/UCP3
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wikidoc
UFM1
UFM1 Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene. UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1) and E2-like conjugating enzyme UFC1 (see UBE2M). # Function UFM1 shares several common propert...
UFM1 Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene.[1][2] UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1) and E2-like conjugating enzyme UFC1 (see UBE2M).[2] # Function UFM1 shares several comm...
https://www.wikidoc.org/index.php/UFM1
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wikidoc
UGCG
UGCG Ceramide glucosyltransferase is an enzyme that in humans is encoded by the UGCG gene. Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular process...
UGCG Ceramide glucosyltransferase is an enzyme that in humans is encoded by the UGCG gene.[1][2][3] Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellul...
https://www.wikidoc.org/index.php/UGCG
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wikidoc
UGGT
UGGT UGGT, or UDP-glucose:glycoprotein glucosyltransferase, is a soluble enzyme resident in the lumen of the endoplasmic reticulum (ER). The main function of UGGT is to recognize misfolded glycoproteins and transfer a glucose (Glc) monomer (monoglucosylate) to the terminal mannose of the A-branch of the glycan on the g...
UGGT UGGT, or UDP-glucose:glycoprotein glucosyltransferase, is a soluble enzyme resident in the lumen of the endoplasmic reticulum (ER).[1] The main function of UGGT is to recognize misfolded glycoproteins and transfer a glucose (Glc) monomer (monoglucosylate) to the terminal mannose of the A-branch of the glycan on t...
https://www.wikidoc.org/index.php/UGGT
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ULK1
ULK1 ULK1 is an enzyme that in humans is encoded by the ULK1 gene. Unc-51 like autophagy activating kinase (ULK1/2) are two similar isoforms of an enzyme that in humans are encoded by the ULK1/2 genes. It is specifically a kinase that is involved with autophagy, particularly in response to amino acid withdrawal. Not ma...
ULK1 ULK1 is an enzyme that in humans is encoded by the ULK1 gene.[1][2] Unc-51 like autophagy activating kinase (ULK1/2) are two similar isoforms of an enzyme that in humans are encoded by the ULK1/2 genes.[5][6] It is specifically a kinase that is involved with autophagy, particularly in response to amino acid withd...
https://www.wikidoc.org/index.php/ULK1
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wikidoc
UPB1
UPB1 Beta-ureidopropionase is an enzyme that in humans is encoded by the UPB1 gene. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of...
UPB1 Beta-ureidopropionase is an enzyme that in humans is encoded by the UPB1 gene.[1][2] This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive ac...
https://www.wikidoc.org/index.php/UPB1
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wikidoc
UPF2
UPF2 Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene. # Function This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs ...
UPF2 Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.[1][2][3] # Function This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects expor...
https://www.wikidoc.org/index.php/UPF2
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wikidoc
UPP1
UPP1 Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene. # Interactions UPP1 has been shown to interact with Vimentin. # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles. - ↑ The interactive pathway map can be edited at WikiPathways: "F...
UPP1 Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene.[1][2][3] # Interactions UPP1 has been shown to interact with Vimentin.[4] # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles.[§ 1] - ↑ The interactive pathway map can be edited a...
https://www.wikidoc.org/index.php/UPP1
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URI1
URI1 Unconventional prefoldin RPB5 interactor, also called URI1, is a protein that in humans is encoded by the URI1 gene. # Function The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibit...
URI1 Unconventional prefoldin RPB5 interactor, also called URI1, is a protein that in humans is encoded by the URI1 gene.[1][2][3] # Function The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to ha...
https://www.wikidoc.org/index.php/URI1
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wikidoc
USF1
USF1 Upstream stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene. # Function This gene encodes a member of the basic helix-loop-helix leucine zipper family and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (In...
USF1 Upstream stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene.[1][2] # Function This gene encodes a member of the basic helix-loop-helix leucine zipper family and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initia...
https://www.wikidoc.org/index.php/USF1
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wikidoc
USF2
USF2 Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene. # Function This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through Pyridine-rich initiator (Inr...
USF2 Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene.[1][2] # Function This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through Pyridine-rich initiat...
https://www.wikidoc.org/index.php/USF2
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wikidoc
USP7
USP7 Ubiquitin-specific-processing protease 7 (USP7), also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP), is an enzyme that in humans is encoded by the USP7 gene. # Function ## Regulation of the p53 tumor suppressor USP7 or HAUSP is a ubiquitin specific...
USP7 Ubiquitin-specific-processing protease 7 (USP7), also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP), is an enzyme that in humans is encoded by the USP7 gene.[1][2][3][4] # Function ## Regulation of the p53 tumor suppressor USP7 or HAUSP is a ubiqu...
https://www.wikidoc.org/index.php/USP7
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wikidoc
UTF1
UTF1 Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is loca...
UTF1 Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. [1] UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells.[2] Its expression is rapidly reduced upon differentiation. UTF1 protein ...
https://www.wikidoc.org/index.php/UTF1
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Ulna
Ulna # Overview The ulna (elbow bone) is a long bone, prismatic in form, placed at the medial side of the forearm, parallel with the radius. # Articulations The ulna articulates with: - the humerus, at the right side elbow as a hinge joint. - the radius, near the elbow as a pivot joint, this allows the radius to cros...
Ulna Template:Infobox Bone # Overview The ulna (elbow bone) is a long bone, prismatic in form, placed at the medial side of the forearm, parallel with the radius. # Articulations The ulna articulates with: - the humerus, at the right side elbow as a hinge joint. - the radius, near the elbow as a pivot joint, this al...
https://www.wikidoc.org/index.php/Ulna
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VAPA
VAPA VAMP-Associated Protein A ( or Vesicle-Associated Membrane Protein-Associated Protein A) is a protein that in humans is encoded by the VAPA gene. Together with VAPB and VAPC it forms the VAP protein family. They are integral endoplasmic reticulum membrane proteins of the type II and are ubiquitous among eukaryotes...
VAPA VAMP-Associated Protein A ( or Vesicle-Associated Membrane Protein-Associated Protein A) is a protein that in humans is encoded by the VAPA gene.[1][2][3] Together with VAPB and VAPC it forms the VAP protein family. They are integral endoplasmic reticulum membrane proteins of the type II and are ubiquitous among ...
https://www.wikidoc.org/index.php/VAPA
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wikidoc
VAPB
VAPB Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. The VAPB gene is found on the 20th human chromosome. Together with VAPA, it forms the VAP protein family. # Function The protein encoded by this gene is a type IV membrane protein found in plasma a...
VAPB Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene.[1][2] The VAPB gene is found on the 20th human chromosome. Together with VAPA, it forms the VAP protein family. # Function The protein encoded by this gene is a type IV membrane protein found in p...
https://www.wikidoc.org/index.php/VAPB
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wikidoc
VAT1
VAT1 Synaptic vesicle membrane protein VAT-1 homolog is a protein that in humans is encoded by the VAT1 gene. Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic syna...
VAT1 Synaptic vesicle membrane protein VAT-1 homolog is a protein that in humans is encoded by the VAT1 gene.[1][2][3] Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholin...
https://www.wikidoc.org/index.php/VAT1
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wikidoc
VAX1
VAX1 Ventral anterior homeobox 1 is a protein that in humans is encoded by the VAX1 gene. # Function This gene appears to influence the development in humans of the forebrain. It is also present in mice and xenopus frogs, which suggests a long evolutionary history, and in those organisms its expression is confined to ...
VAX1 Ventral anterior homeobox 1 is a protein that in humans is encoded by the VAX1 gene.[1][2][3] # Function This gene appears to influence the development in humans of the forebrain. It is also present in mice and xenopus frogs, which suggests a long evolutionary history, and in those organisms its expression is co...
https://www.wikidoc.org/index.php/VAX1
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wikidoc
VWA2
VWA2 von Willebrand factor A domain-containing protein 2, also known as A domain-containing protein similar to matrilin and collagen (AMACO) is a protein that in humans is encoded by the VWA2 gene. AMACO is a member of the von Willebrand factor A-like (VWA) domain containing protein superfamily and consists of three VW...
VWA2 von Willebrand factor A domain-containing protein 2, also known as A domain-containing protein similar to matrilin and collagen (AMACO) is a protein that in humans is encoded by the VWA2 gene.[1][2] AMACO is a member of the von Willebrand factor A-like (VWA) domain containing protein superfamily and consists of t...
https://www.wikidoc.org/index.php/VWA2
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wikidoc
Volt
Volt The volt (symbol: V) is the SI derived unit of electric potential difference or electromotive force. It is named in honor of the Lombard physicist Alessandro Volta (1745–1827), who invented the voltaic pile, the first modern chemical battery. # Definition The volt is defined as the potential difference across a ...
Volt Template:Otheruses4 The volt (symbol: V) is the SI derived unit of electric potential difference or electromotive force.[1][2] It is named in honor of the Lombard physicist Alessandro Volta (1745–1827), who invented the voltaic pile, the first modern chemical battery. # Definition The volt is defined as the pot...
https://www.wikidoc.org/index.php/Volt
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wikidoc
WBP2
WBP2 WW domain-binding protein 2 is a protein that in humans is encoded by the WBP2 gene. The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interac...
WBP2 WW domain-binding protein 2 is a protein that in humans is encoded by the WBP2 gene.[1][2] The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein ...
https://www.wikidoc.org/index.php/WBP2
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wikidoc
WDR3
WDR3 WD repeat-containing protein 3 is a protein that in humans is encoded by the WDR3 gene. This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belo...
WDR3 WD repeat-containing protein 3 is a protein that in humans is encoded by the WDR3 gene.[1][2] This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Protei...
https://www.wikidoc.org/index.php/WDR3
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wikidoc
WDR5
WDR5 WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of hetero...
WDR5 WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.[1][2] This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of...
https://www.wikidoc.org/index.php/WDR5
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wikidoc
WFS1
WFS1 Wolframin is a protein that in humans is encoded by the WFS1 gene. # Function Wolframin is a transmembrane protein. Wolframin appears to function as a cation-selective ion channel. # Clinical significance Mutations in this gene are associated with an autosomal recessive syndrome characterized by insulin-dependen...
WFS1 Wolframin is a protein that in humans is encoded by the WFS1 gene.[1][2][3] # Function Wolframin is a transmembrane protein.[3] Wolframin appears to function as a cation-selective ion channel.[4] # Clinical significance Mutations in this gene are associated with an autosomal recessive syndrome characterized by ...
https://www.wikidoc.org/index.php/WFS1
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wikidoc
WNK1
WNK1 WNK (lysine deficient protein kinase 1), also known as WNK1, is an enzyme that is encoded by the WNK1 gene. WNK1 is serine-threonine kinase and part of the "with no lysine/K" kinase WNK family. The predominant role of WNK1 is the regulation of cation-Cl− cotransporters (CCCs) such as the sodium chloride cotranspor...
WNK1 WNK (lysine deficient protein kinase 1), also known as WNK1, is an enzyme that is encoded by the WNK1 gene.[1][2][3][4][5] WNK1 is serine-threonine kinase and part of the "with no lysine/K" kinase WNK family.[1][2][3][5] The predominant role of WNK1 is the regulation of cation-Cl− cotransporters (CCCs) such as th...
https://www.wikidoc.org/index.php/WNK1
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wikidoc
WNK4
WNK4 Serine/threonine-protein kinase WNK4 also known as WNK lysine deficient protein kinase 4 or WNK4, is an enzyme that in humans is encoded by the WNK4 gene.. Missense mutations cause a genetic form of pseudohypoaldosteronism type 2, also called Gordon syndrome. # Function The WNK4 gene encodes a serine-threonine ki...
WNK4 Serine/threonine-protein kinase WNK4 also known as WNK lysine deficient protein kinase 4 or WNK4, is an enzyme that in humans is encoded by the WNK4 gene.[1]. Missense mutations cause a genetic form of pseudohypoaldosteronism type 2, also called Gordon syndrome. # Function The WNK4 gene encodes a serine-threonin...
https://www.wikidoc.org/index.php/WNK4
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wikidoc
WNT4
WNT4 WNT4 is a secreted protein that in humans is encoded by the Wnt4 gene, found on chromosome 1. It promotes female sex development and represses male sex development. Loss of function can have serious consequences, such as female to male sex reversal. # Function The WNT gene family consists of structurally related...
WNT4 WNT4 is a secreted protein that in humans is encoded by the Wnt4 gene, found on chromosome 1.[1][2] It promotes female sex development and represses male sex development. Loss of function can have serious consequences, such as female to male sex reversal. # Function The WNT gene family consists of structurally ...
https://www.wikidoc.org/index.php/WNT4
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wikidoc
WNT6
WNT6 Wingless-type MMTV integration site family, member 6, also known as WNT6, is a human gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate...
WNT6 Wingless-type MMTV integration site family, member 6, also known as WNT6, is a human gene.[1][2] The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of ce...
https://www.wikidoc.org/index.php/WNT6
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wikidoc
WWC1
WWC1 Protein KIBRA also known as kidney and brain expressed protein (KIBRA) or WW domain-containing protein 1 (WWC1) is a protein that in humans is encoded by the WWC1 gene. # Research on human memory A single nucleotide polymorphism (rs17070145) in the gene has been associated with human memory performance in one 2...
WWC1 Protein KIBRA also known as kidney and brain expressed protein (KIBRA) or WW domain-containing protein 1 (WWC1) is a protein that in humans is encoded by the WWC1 gene.[1][2][3] # Research on human memory A single nucleotide polymorphism (rs17070145) [4] in the gene has been associated with human memory perform...
https://www.wikidoc.org/index.php/WWC1
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wikidoc
WWC2
WWC2 WW and C2 domain containing 2 (WWC2) is a protein that in humans is encoded by the WWC2 gene (4q35.1). Though function of WWC2 remains unknown, it has been predicted that WWC2 may play a role in cancer. # Gene Locus The human gene WWC2 is found on chromosome 4 at band 4q35.1. The gene is found on the plus strand ...
WWC2 WW and C2 domain containing 2 (WWC2) is a protein that in humans is encoded by the WWC2 gene (4q35.1). Though function of WWC2 remains unknown, it has been predicted that WWC2 may play a role in cancer. # Gene Locus The human gene WWC2 is found on chromosome 4 at band 4q35.1. The gene is found on the plus strand...
https://www.wikidoc.org/index.php/WWC2
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wikidoc
WWOX
WWOX WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. # Function WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This ...
WWOX WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene.[1][2][3][4] # Function WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA sp...
https://www.wikidoc.org/index.php/WWOX
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wikidoc
WWP2
WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 also known as atrophin-1-interacting protein 2 (AIP2) or WW domain-containing protein 2 (WWP2) is an enzyme that in humans is encoded by the WWP2 gene. # Function This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubi...
WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 also known as atrophin-1-interacting protein 2 (AIP2) or WW domain-containing protein 2 (WWP2) is an enzyme that in humans is encoded by the WWP2 gene.[1][2][3] # Function This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to p...
https://www.wikidoc.org/index.php/WWP2
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wikidoc
Wee1
Wee1 Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). Wee1 has a molecular mass of 96 kDa and it is a key regulator of cell cycle progression. It influences cell size by inhibiting the entry into mitosis, through inhibiting Cdk1. It...
Wee1 Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). Wee1 has a molecular mass of 96 kDa and it is a key regulator of cell cycle progression. It influences cell size by inhibiting the entry into mitosis, through inhibiting Cdk1. I...
https://www.wikidoc.org/index.php/Wee1
1e4ac83ed35b287fc10a0cf85f91db52c1615638
wikidoc
Wiki
Wiki # Overview A wiki is a collection of web pages designed to enable anyone who accesses it to contribute or modify content, using a simplified markup language. Wikis are often used to create collaborative websites and to power community websites. For example, the collaborative encyclopedia Wikipedia is one of the b...
Wiki Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A wiki is a collection of web pages designed to enable anyone who accesses it to contribute or modify content, using a simplified markup language[1][2]. Wikis are often used to create collaborative websites and to power community websites. For example...
https://www.wikidoc.org/index.php/Wiki
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wikidoc
Wood
Wood Wood is hard, fibrous, lignified structural tissue produced as secondary xylem in the stems of woody plants, notably trees but also shrubs. This tissue conducts water to the leaves and other growing tissues and has a support function, enabling plants to reach large sizes. Wood may also refer to other plant materia...
Wood Wood is hard, fibrous, lignified structural tissue produced as secondary xylem in the stems of woody plants, notably trees but also shrubs. This tissue conducts water to the leaves and other growing tissues and has a support function, enabling plants to reach large sizes. Wood may also refer to other plant materi...
https://www.wikidoc.org/index.php/Wood
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wikidoc
XBP1
XBP1 X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located on chromosome 22 while a closely related pseudogene has been identified and localized to chromosome 5. The XBP1 protein is a transcription factor that regulates the expression of genes i...
XBP1 X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene.[1][2] The XBP1 gene is located on chromosome 22 while a closely related pseudogene has been identified and localized to chromosome 5.[3] The XBP1 protein is a transcription factor that regulates the expression ...
https://www.wikidoc.org/index.php/XBP1
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wikidoc
XCL1
XCL1 Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the C chemokine family that is also known as lymphotactin. Chemokines are known for their function in inflammatory and immunological responses. This family C chemokines differs in structure and function from most chemokines. There are only two che...
XCL1 Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the C chemokine family that is also known as lymphotactin. Chemokines are known for their function in inflammatory and immunological responses. This family C chemokines differs in structure and function from most chemokines.[1][2] There are only ...
https://www.wikidoc.org/index.php/XCL1
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wikidoc
XCR1
XCR1 The "C" sub-family of chemokine receptors contains only one member: XCR1, the receptor for XCL1 and XCL2 (or lymphotactin-1 and -2). XCR1 is also known as GPR5. # Function The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are chara...
XCR1 The "C" sub-family of chemokine receptors contains only one member: XCR1, the receptor for XCL1 and XCL2 (or lymphotactin-1 and -2). XCR1 is also known as GPR5. # Function The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are char...
https://www.wikidoc.org/index.php/XCR1
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wikidoc
XIAP
XIAP X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of the Inhibitor of apoptosis family of proteins (IAP). IAPs were initially identified in baculoviruses, but XIAP is one of the homologous proteins found in mammals. It is so called because it was first discovered by a 273 base pair site on the X chromosom...
XIAP X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of the Inhibitor of apoptosis family of proteins (IAP). IAPs were initially identified in baculoviruses, but XIAP is one of the homologous proteins found in mammals.[1] It is so called because it was first discovered by a 273 base pair site on the X chrom...
https://www.wikidoc.org/index.php/XIAP
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wikidoc
XIST
XIST Xist (X-inactive specific transcript) is an RNA gene on the X chromosome of the placental mammals that acts as a major effector of the X inactivation process. It is a component of the Xic – X-chromosome inactivation centre – along with two other RNA genes (Jpx and Ftx) and two protein genes (Tsx and Cnbp2). The Xi...
XIST Xist (X-inactive specific transcript) is an RNA gene on the X chromosome of the placental mammals that acts as a major effector of the X inactivation process.[1] It is a component of the Xic – X-chromosome inactivation centre[2] – along with two other RNA genes (Jpx and Ftx) and two protein genes (Tsx and Cnbp2)....
https://www.wikidoc.org/index.php/XIST
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wikidoc
XPO1
XPO1 Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA. # History XPO1 (CRM1) originally was identified in the fission yeast Schizosaccharomyces pombe in a genetic screen, and investigators determined th...
XPO1 Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.[1][2][3][4] # History XPO1 (CRM1) originally was identified in the fission yeast Schizosaccharomyces pombe in a genetic screen, and investigators ...
https://www.wikidoc.org/index.php/XPO1
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wikidoc
XPO5
XPO5 Exportin-5 (XPO5) is a protein that, in humans, is encoded by the XPO5 gene. In eukaryotic cells, the primary purpose of XPO5 is to export pre-microRNA (also known as pre-miRNA) out of the nucleus and into the cytoplasm, for further processing by the Dicer enzyme. Once in the cytoplasm, the microRNA (also known as...
XPO5 Exportin-5 (XPO5) is a protein that, in humans, is encoded by the XPO5 gene.[1][2][3] In eukaryotic cells, the primary purpose of XPO5 is to export pre-microRNA (also known as pre-miRNA) out of the nucleus and into the cytoplasm, for further processing by the Dicer enzyme.[4][5][6][7] Once in the cytoplasm, the m...
https://www.wikidoc.org/index.php/XPO5
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wikidoc
Xist
Xist # Overview Xist is an RNA gene on the X chromosome of the placental mammals that acts as major effector of the X inactivation process. The Xist RNA, a large (18 kb) transcript, is expressed on the inactive chromosome and not on the active one. It is processed similarly to mRNAs, through splicing and polyadenylati...
Xist # Overview Xist is an RNA gene on the X chromosome of the placental mammals that acts as major effector of the X inactivation process. The Xist RNA, a large (18 kb) transcript, is expressed on the inactive chromosome and not on the active one. It is processed similarly to mRNAs, through splicing and polyadenylati...
https://www.wikidoc.org/index.php/Xist
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wikidoc
Xq28
Xq28 Xq28 is a chromosome band and genetic marker situated at the tip of the X chromosome which has been studied since at least 1980. The band contains three distinct regions, totaling about 8 Mbp of genetic information. The marker came to the public eye in 1993 when studies by Dean Hamer and others indicated a link be...
Xq28 Xq28 is a chromosome band and genetic marker situated at the tip of the X chromosome which has been studied since at least 1980.[1] The band contains three distinct regions, totaling about 8 Mbp of genetic information.[2] The marker came to the public eye in 1993 when studies by Dean Hamer and others indicated a ...
https://www.wikidoc.org/index.php/Xq28
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wikidoc
YAP1
YAP1 YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcriptional regulator by activating the transcription of genes involved in cell proliferation and suppressing apoptotic genes. YAP1 is inhibited in the Hippo signaling pathway which allows the cellular control of organ siz...
YAP1 YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcriptional regulator by activating the transcription of genes involved in cell proliferation and suppressing apoptotic genes. YAP1 is inhibited in the Hippo signaling pathway which allows the cellular control of organ si...
https://www.wikidoc.org/index.php/YAP1
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wikidoc
YARS
YARS Tyrosyl-tRNA synthetase, cytoplasmic, also known as Tyrosine-tRNA ligase, is an enzyme that in humans is encoded by the YARS gene. Living cells translate DNA sequences into RNA sequences and then into protein sequences. Proteins are chains of amino acids, such as tyrosine. As the protein grows, each amino acid is ...
YARS Tyrosyl-tRNA synthetase, cytoplasmic, also known as Tyrosine-tRNA ligase, is an enzyme that in humans is encoded by the YARS gene.[1][2][3] Living cells translate DNA sequences into RNA sequences and then into protein sequences. Proteins are chains of amino acids, such as tyrosine. As the protein grows, each amin...
https://www.wikidoc.org/index.php/YARS
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wikidoc
YES1
YES1 Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate...
YES1 Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene.[1][2] This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thym...
https://www.wikidoc.org/index.php/YES1
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wikidoc
Yawn
Yawn A yawn (synonyms chasma, pandiculation, oscitation from the Latin verb oscitare, to open the mouth wide ) is a reflex of deep inhalation and exhalation associated with tiredness, stress, over-work, lack of stimulation, or boredom. Pandiculation is the term for the act of stretching and yawning. Yawning is a powerf...
Yawn A yawn (synonyms chasma, pandiculation[1], oscitation from the Latin verb oscitare, to open the mouth wide [2] ) is a reflex of deep inhalation and exhalation associated with tiredness, stress, over-work, lack of stimulation, or boredom. Pandiculation is the term for the act of stretching and yawning.[1] Yawning ...
https://www.wikidoc.org/index.php/Yawn
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wikidoc
Yoga
Yoga Yoga (Sanskrit: योग Yoga, Template:IPA2) is a group of ancient spiritual practices originating in India. According to Gavin Flood, Academic Director of the Oxford Centre for Hindu Studies it has been defined as referring to "technologies or disciplines of asceticism and meditation which are thought to lead to spir...
Yoga Yoga (Sanskrit: योग Yoga, Template:IPA2) is a group of ancient spiritual practices originating in India. According to Gavin Flood, Academic Director of the Oxford Centre for Hindu Studies[1] it has been defined as referring to "technologies or disciplines of asceticism and meditation which are thought to lead to ...
https://www.wikidoc.org/index.php/Yoga
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wikidoc
ZBP1
ZBP1 Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the ZBP1 gene. ZBP1 is also an abbreviation for chicken or rat β-actin zipcode-binding protein 1, a homolog of the human insulin-like growth factor 2 mRNA-binding prot...
ZBP1 Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the ZBP1 gene.[1][2] ZBP1 is also an abbreviation for chicken or rat β-actin zipcode-binding protein 1, a homolog of the human insulin-like growth factor 2 mRNA-bindi...
https://www.wikidoc.org/index.php/ZBP1
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wikidoc
ZEB1
ZEB1 Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene. ZEB1 (previously known as TCF8) encodes a zinc finger and homeodomain transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the...
ZEB1 Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene.[1][2][3] ZEB1 (previously known as TCF8) encodes a zinc finger and homeodomain transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-pr...
https://www.wikidoc.org/index.php/ZEB1
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wikidoc
ZEB2
ZEB2 Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 protein is a transcription factor that plays a role in the transforming growth factor β (TGFβ) signaling pathways that are essential during early fetal development. # Function ZEB2 (previously also known as SMAD...
ZEB2 Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene.[1] The ZEB2 protein is a transcription factor that plays a role in the transforming growth factor β (TGFβ) signaling pathways that are essential during early fetal development.[2] # Function ZEB2 (previously also known ...
https://www.wikidoc.org/index.php/ZEB2
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wikidoc
ZIC2
ZIC2 Zinc finger protein ZIC2 is a protein that in humans is encoded by the ZIC2 gene. ZIC2 is a member of the Zinc finger of the cerebellum (ZIC) protein family. # Function ZIC2 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA and protein...
ZIC2 Zinc finger protein ZIC2 is a protein that in humans is encoded by the ZIC2 gene.[1][2] ZIC2 is a member of the Zinc finger of the cerebellum (ZIC) protein family.[3] # Function ZIC2 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA a...
https://www.wikidoc.org/index.php/ZIC2
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wikidoc
ZIC3
ZIC3 ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family. ZIC3 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA and proteins. Correct function of this protein family in critical for early development, and as such muta...
ZIC3 ZIC3 is a member of the Zinc finger of the cerebellum (ZIC) protein family.[1][2] ZIC3 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact with DNA and proteins. Correct function of this protein family in critical for early development, and as su...
https://www.wikidoc.org/index.php/ZIC3
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wikidoc
ZIP9
ZIP9 Zinc transporter ZIP9 also known as Zrt- and Irt-like protein 9 (ZIP9) and solute carrier family 39 member 9 (SLC39A9) is a protein that in humans is encoded by the SLC39A9 gene. This protein is the 9th member out of 14 ZIP family proteins, which is a membrane androgen receptor (mAR) coupled to G proteins, and als...
ZIP9 Zinc transporter ZIP9 also known as Zrt- and Irt-like protein 9 (ZIP9) and solute carrier family 39 member 9 (SLC39A9) is a protein that in humans is encoded by the SLC39A9 gene.[1] This protein is the 9th member out of 14 ZIP family proteins, which is a membrane androgen receptor (mAR) coupled to G proteins, and...
https://www.wikidoc.org/index.php/ZIP9
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wikidoc
ZW10
ZW10 Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and earl...
ZW10 Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene.[1][2] This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, a...
https://www.wikidoc.org/index.php/ZW10
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wikidoc
ZZZ3
ZZZ3 ZZ-type zinc finger-containing protein 3 is a protein that in humans is encoded by the ZZZ3 gene. # Model organisms Model organisms have been used in the study of ZZZ3 function. A conditional knockout mouse line, called Zzz3tm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium prog...
ZZZ3 ZZ-type zinc finger-containing protein 3 is a protein that in humans is encoded by the ZZZ3 gene.[1] # Model organisms Model organisms have been used in the study of ZZZ3 function. A conditional knockout mouse line, called Zzz3tm1a(EUCOMM)Wtsi[5][6] was generated as part of the International Knockout Mouse Conso...
https://www.wikidoc.org/index.php/ZZZ3
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wikidoc
Ziac
Ziac Synonyms / Brand Names: Bisoprolol Fumarate, Bisoprolol fumerate, Bisoprolol Hemifumarate, Cardicor, Concor, Condyline, Detensiel, Emconcor, Emcor, Euradal, Isoten, Monocor, Soloc, Soprol, Zebeta # Dosing and Administration Bisoprolol is an effective treatment of hypertension in once-daily doses of 2.5 to 40 mg, ...
Ziac Synonyms / Brand Names: Bisoprolol Fumarate, Bisoprolol fumerate, Bisoprolol Hemifumarate, Cardicor, Concor, Condyline, Detensiel, Emconcor, Emcor, Euradal, Isoten, Monocor, Soloc, Soprol, Zebeta Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Dosing and Administration Bisoprolol is an effective treatment o...
https://www.wikidoc.org/index.php/Ziac
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wikidoc
Élan
Élan Élan Corporation plc (Template:Nyse, Template:Lse) is a major drugs firm based in Athlone, County Westmeath, Ireland which has major interests in the United States. In the late 1990's its value on the Irish Stock Exchange reached over €20bn. It has secondary listings on the London Stock Exchange and the New York S...
Élan Élan Corporation plc (Template:Nyse, Template:Lse) is a major drugs firm based in Athlone, County Westmeath, Ireland which has major interests in the United States. In the late 1990's its value on the Irish Stock Exchange reached over €20bn. It has secondary listings on the London Stock Exchange and the New York ...
https://www.wikidoc.org/index.php/%C3%89lan
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wikidoc
PMA
PMA # Overview PMA (paramethoxyamphetamine, p-methoxyamphetamine or 4-methoxyamphetamine) is a synthetic phenethylamine drug, psychostimulant and hallucinogen. It is commonly sold as "Ecstasy" and both dealers and users are likely to be unaware that a particular batch of pills contains PMA rather than MDMA. Notable ba...
PMA Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] # Overview PMA (paramethoxyamphetamine, p-methoxyamphetamine or 4-methoxyamphetamine) is a synthetic phenethylamine drug, psychostimulant and hallucinogen. It is commonly sold as "Ecstasy" and both dealers and users are likely to be unaware that a particular batc...
https://www.wikidoc.org/index.php/4-MA
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wikidoc
68W
68W # Overview 68W (often pronounced as 6 8 Whiskey using the phonetic alphabet) is the Military Occupational Specialty (MOS) for the United States Army's healthcare specialist, also known as the combat medic. # Description The main role of the 68W in the United States Army is to provide medical treatment to wounded ...
68W # Overview 68W (often pronounced as 6 8 Whiskey using the phonetic alphabet) is the Military Occupational Specialty (MOS) for the United States Army's healthcare specialist, also known as the combat medic. # Description The main role of the 68W in the United States Army is to provide medical treatment to wounded ...
https://www.wikidoc.org/index.php/68W
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wikidoc
AK2
AK2 Adenylate kinase 2 is an enzyme that is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion. # Function Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups amo...
AK2 Adenylate kinase 2 is an enzyme that is encoded in humans by the AK2 gene.[1][2][3] The AK2 protein is found in the intermembrane space of the mitochondrion.[4][5] # Function Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phos...
https://www.wikidoc.org/index.php/AK2
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wikidoc
AKT
AKT # Overview Akt1, also known as "Akt" or protein kinase B (PKB) is an important molecule in mammalian cellular signaling. # AKT family: AKT1, AKT2, AKT3 In humans, there are three genes in the "Akt family": Akt1, Akt2, and Akt3. These enzymes are members of the serine/threonine-specific protein kinase family (EC ...
AKT # Overview Akt1, also known as "Akt" or protein kinase B (PKB) is an important molecule in mammalian cellular signaling. # AKT family: AKT1, AKT2, AKT3 In humans, there are three genes in the "Akt family": Akt1, Akt2, and Akt3. These enzymes are members of the serine/threonine-specific protein kinase family (EC ...
https://www.wikidoc.org/index.php/AKT
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wikidoc
APC
APC Apc may refer to: - Apc, Hungary, a village in the Heves county of Hungary APC may also refer to: - APC (gene), a human gene that is classified as a tumor suppressor gene - Activated protein C, a protein involved in blood coagulation - Allophycocyanin, a protein from the light-harvesting phycobiliprotein family - A...
APC Template:TOCright Apc may refer to: - Apc, Hungary, a village in the Heves county of Hungary APC may also refer to: - APC (gene), a human gene that is classified as a tumor suppressor gene - Activated protein C, a protein involved in blood coagulation - Allophycocyanin, a protein from the light-harvesting phycobil...
https://www.wikidoc.org/index.php/APC
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wikidoc
Abc
Abc Synonyms and keywords: # Special consideration when adding information from observational studies # Overview # Historical Perspective was first discovered by , a , in /during/following . The association between and was made in/during . In , was the first to discover the association between and the developme...
Abc Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Synonyms and keywords: # Special consideration when adding information from observational studies # Overview # Historical Perspective [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [ye...
https://www.wikidoc.org/index.php/Abc
8a3813c8f9084e6149fc0f9198e9030a6a8911bb
wikidoc
Ion
Ion An ion is an atom or molecule which has lost or gained one or more valence electrons, giving it a positive or negative electrical charge. A negatively charged ion, which has more electrons in its electron shells than it has protons in its nuclei, is known as an anion (Template:PronEng; an-eye-on). Conversely, a pos...
Ion Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] An ion is an atom or molecule which has lost or gained one or more valence electrons, giving it a positive or negative electrical charge. A negatively charged ion, which has more electrons in its electron shells than it has protons in its nuclei, is known as an an...
https://www.wikidoc.org/index.php/Anion
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wikidoc
Arm
Arm # Overview In anatomy, an arm is one of the upper limbs of an animal. The term arm can also be used for analogous structures, such as one of the paired upper limbs of a four-legged animal, or the arms of an octopus. Anatomically, the term arm refers specifically to the segment between the shoulder and the elbow. T...
Arm Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview In anatomy, an arm is one of the upper limbs of an animal. The term arm can also be used for analogous structures, such as one of the paired upper limbs of a four-legged animal, or the arms of an octopus. Anatomically, the term arm refers specifically ...
https://www.wikidoc.org/index.php/Arm
81c20f0a04e961e6423e2e3768ae5417843d30e9
wikidoc
BSc
BSc A Bachelor of Science (B.S., B.Sc. or less commonly, S.B. or Sc.B. from the Latin Scientiæ Baccalaureus) is an undergraduate academic degree awarded for completed courses that generally last three to five years (see below). In the United States, a Bachelor of Science degree may be a more specialized version of B.A....
BSc A Bachelor of Science (B.S., B.Sc. or less commonly, S.B. or Sc.B. from the Latin Scientiæ Baccalaureus) is an undergraduate academic degree awarded for completed courses that generally last three to five years (see below). In the United States, a Bachelor of Science degree may be a more specialized version of B.A...
https://www.wikidoc.org/index.php/BSc
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wikidoc
Bee
Bee Bees are flying insects closely related to wasps and ants. Bees are a monophyletic lineage within the superfamily Apoidea, presently classified by the unranked taxon name Anthophila. There are slightly fewer than 20,000 known species of bee, in 9 recognized families, though many are undescribed and the actual numbe...
Bee Template:Otheruses6 Template:For2 Bees are flying insects closely related to wasps and ants. Bees are a monophyletic lineage within the superfamily Apoidea, presently classified by the unranked taxon name Anthophila. There are slightly fewer than 20,000 known species of bee, in 9 recognized families,[1] though man...
https://www.wikidoc.org/index.php/Bee
fbd648696fdcd7aa73be55dd44da45aa2cfead6a
wikidoc
HBB
HBB Beta globin (also referred to as HBB, β-globin, haemoglobin beta, hemoglobin beta, or preferably haemoglobin subunit beta) is a globin protein, which along with alpha globin (HBA), makes up the most common form of haemoglobin in adult humans, the HbA. It is 146 amino acids long and has a molecular weight of 15,867 ...
HBB Associate Editor(s)-in-Chief: Henry A. Hoff Beta globin (also referred to as HBB, β-globin, haemoglobin beta, hemoglobin beta, or preferably haemoglobin subunit beta) is a globin protein, which along with alpha globin (HBA), makes up the most common form of haemoglobin in adult humans, the HbA.[1] It is 146 amino...
https://www.wikidoc.org/index.php/Beta-globin
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wikidoc
Myc
Myc Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc, l-myc, and n-myc. c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc. In cance...
Myc Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc, l-myc, and n-myc. c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc. In canc...
https://www.wikidoc.org/index.php/C-myc
3d0a8e7a952ac1a50f8fcabd6de31fd53d2f7482
wikidoc
C3b
C3b C3b is a one of the elements formed by the cleavage of complement component 3. C3b may bind to microbial cell surfaces within an organism's body. This can lead to the production of surface-bound C3 convertase and thus more C3b components. Also known as C3bBb, this convertase is similar to soluble C3-convertase exce...
C3b Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] C3b is a one of the elements formed by the cleavage of complement component 3. C3b may bind to microbial cell surfaces within an organism's body. This can lead to the production of surface-bound C3 convertase and thus more C3b components. Also known as C3bBb, this...
https://www.wikidoc.org/index.php/C3b
23f50ed6dee9c6894fd30f0b90db6a4d8f8aeb9f
wikidoc
CD1
CD1 CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. However their precise function is unknown. # Types CD1 glycoproteins...
CD1 CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. However their precise function is unknown.[1] # Types CD1 glycoprot...
https://www.wikidoc.org/index.php/CD1
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wikidoc
CD2
CD2 CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. # Function It interacts with other adhesion molecules, such as ...
CD2 CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2,[1] LFA-3 receptor, erythrocyte receptor and rosette receptor.[2] # Function It interacts with other adhesion molecules, s...
https://www.wikidoc.org/index.php/CD2
70b2f2334cf80927c6d76404433ed6c8da7ae66a
wikidoc
CD4
CD4 In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) ...
CD4 In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it)...
https://www.wikidoc.org/index.php/CD4
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wikidoc
CD6
CD6 CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. # Function This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activat...
CD6 CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene.[1][2] # Function This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an ...
https://www.wikidoc.org/index.php/CD6
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wikidoc
CD8
CD8 CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encode...
CD8 CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein.[2] There are two isoforms of the protein, alpha and beta, each en...
https://www.wikidoc.org/index.php/CD8
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wikidoc
CD9
CD9 CD9 antigen is a protein that in humans is encoded by the CD9 gene. # Function The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. T...
CD9 CD9 antigen is a protein that in humans is encoded by the CD9 gene.[1] # Function The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domain...
https://www.wikidoc.org/index.php/CD9
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wikidoc
CLS
CLS CLS may refer to: # Education and society ## Academic fields - Critical legal studies, a contentious school of legal philosophy, that emerged from Harvard Law School in the 1980s. - Critical language studies - the study of language that evolved into critical discourse analysis ## Educational institutions - City ...
CLS CLS may refer to: # Education and society ## Academic fields - Critical legal studies, a contentious school of legal philosophy, that emerged from Harvard Law School in the 1980s. - Critical language studies - the study of language that evolved into critical discourse analysis ## Educational institutions - City...
https://www.wikidoc.org/index.php/CLS