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0 | Adjuvant radiotherapy versus combined sequential chemotherapy followed by radiotherapy in the treatment of resected nonsmall cell lung carcinoma. A randomized trial of 267 patients. GETCB (Groupe d'Etude et de Traitement des Cancers Bronchiques) | Reconstruction After Skin Cancer | METHODSFrom October, 1982, to November, 1986, 267 patients with resected NSCLC were included in a randomized trial. The adjuvant allocated treatments were either postoperative radiotherapy, 60 Gy in 6 weeks (radiotherapy group = 129 patients), or three courses of postoperative COPAC (cyclophosphamide, doxorubicin, cisp... |
0 | Recent approaches to periodontal therapy | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Periodontal diseases encompass a variety of disease classifications, all involving inflammation of the supporting tissues of the teeth. When progressive, these diseases ultimately lead to the destruction of attachment apparatus including bone and periodontal ligament, culminating in eventual tooth loss. Inflammation ex... |
0 | Hereditary amyloidosis: evidence against early amyloid deposition | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Twelve members of the Indiana hereditary amyloidosis type II kindred were tested for the presence of amyloid deposits. All were young adults (age 26-37), with no evidence of disease and with 1 affected parent. Six were found to be carriers of the variant gene, by DNA testing and/or reduced serum retinol-binding protein... |
0 | Chemokine receptor CCR6 as a prognostic factor after hepatic resection for hepatocellular carcinoma | MSTS 2018 - Femur Mets and MM | BACKGROUND AND AIMS: Chemokines and their receptors have recently been shown to have major roles in cancer metastasis. The aim of this study was to determine whether the interaction between chemokine receptor 6 (CCR6) and its ligand, macrophage inflammatory protein-3 alpha (MIP-3alpha), correlates with metastasis of he... |
0 | Microbiology of the infected total joint arthroplasty | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Infection associated with arthroplasty is a relatively rare event, but when it does occur, it is of major consequence for the patient. Many organisms can cause these infections, but most are the results of gram-positive bacteria, with the genus Staphylococcus accounting for at least 50%. Streptococcus and aerobic gram-... |
0 | Open pelvic fracture: an injury for trauma centers | DoD LSA (Limb Salvage vs Amputation) | Twenty-seven blunt trauma patients with open pelvic fracture who were seen in a trauma center over a 10-year period were characterized for treatment and resource consumption. Age, injury severity score, mortality, mechanism of injury, associated injuries, blood requirement, length of stay (LOS), surgical procedures, an... |
0 | Subtrochanteric femoral fractures: A comparative study of the long proximal femoral nail and the long trochanteric fixation nail | Management of Hip Fractures in the Elderly | Subtrochanteric femoral fractures are expected to increase in the coming years. Despite the improvement of implants and surgical techniques, failures due to complications are still considerable. This article reports a retrospective review of patients who showed a subtrochanteric femoral fracture and who were treated co... |
1 | Modification of a Validated Risk Stratification Tool to Characterize Geriatric Hip Fracture Outcomes and Optimize Care in a Post COVID-19 World | Coronavirus Disease 2019 (COVID-19) | OBJECTIVES: 1. To demonstrate how a risk assessment tool modified to account for the COVID-19 virus during the current global pandemic is able to provide risk assessment for low-energy geriatric hip fracture patients. 2. To provide a treatment algorithm for care of COVID-19 positive/suspected hip fractures patients tha... |
0 | Oblique Lateral Closing-Wedge Osteotomy for Cubitus Varus in Skeletally Immature Patients | Pediatric Supracondylar Humerus Fracture 2020 Review | BACKGROUND: We perform an oblique lateral closing-wedge osteotomy of the distal end of the humerus to correct cubitus varus deformity in children. This deformity is often the consequence of undertreatment, malreduction, or malunion of supracondylar humeral fractures(1). Although standard arcs of motion may be altered, ... |
0 | Neuromuscular complications of acromegaly | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Seventeen consecutive acromegalic patients were evaluated for evidence of neuromuscular dysfunction and followed for 1 year after hypophysectomy. Before treatment, four patients had both a myopathy and the carpal tunnel syndrome, five had myopathy alone, four had carpal tunnel syndrome alone, and four had neither. The ... |
0 | New developments in post-transplant maintenance treatment of multiple myeloma | MSTS 2018 - Femur Mets and MM | Treatment of multiple myeloma (MM) has evolved significantly over the past two decades with high-dose chemotherapy and autologous stem cell transplant (ASCT), incorporating novel therapies such as proteasome inhibitors (PIs) and immunomodulatory drugs (IMiDs) during induction and post-transplant maintenance therapies. ... |
0 | The excess risk of major osteoporotic fractures in hypothyroidism is driven by cumulative hyperthyroid as opposed to hypothyroid time: An observational register-based time-resolved cohort analysis | AAHKS (2) Corticosteroids | The long-term relationship between hypothyroidism and fracture risk is challenging to dissect because of the modifying influence of subsequent thyroxine replacement with the potential for excessive replacement doses. We studied changes in serum thyrotropin concentration (TSH) over time and association with fracture ris... |
0 | Treatment of Colles' fracture. A prospective comparison of three different positions of immobilization | Distal Radius Fractures | The usual treatment of Colles' fracture, i.e. fracture of the distal radius with dorsal angulation of the distal fragment, is closed reduction and immobilization in a plaster cast. The position of the forearm in the cast varies, according to the reports of various authors. Forty-two extra-articular-fractures of the dis... |
0 | Imaging in early posttraumatic complex regional pain syndrome: a comparison of diagnostic methods | Distal Radius Fractures | OBJECTIVES: The complex regional pain syndrome type I (CRPS I) still is difficult to diagnose in posttraumatic patients. As CRPS I is a clinical diagnosis the characteristic symptoms have to be differentiated from normal posttraumatic states. Several diagnostic procedures are applied to facilitate an early diagnosis, a... |
1 | Second-Look Arthroscopic Evaluation of Cartilage Lesions After Mesenchymal Stem Cell Implantation in Osteoarthritic Knees | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Cartilage regenerative procedures have been receiving increased interest because of their potential to alter the progression of osteoarthritis (OA). The application of mesenchymal stem cells (MSCs) has been proposed as a new treatment option for OA based on the ability of these cells to differentiate into c... |
0 | Early perioperative complication rates and subsidence with the Tribute® short cementless, tapered stem in primary total hip arthroplasty | Hip Fx in the Elderly 2019 | This study examined early perioperative complications and subsidence following total hip arthroplasty (THA) with a short femoral stem. A retrospective review of 207 consecutive patients (247 hips) having undergone THA via the direct anterior approach produced only six perioperative complications: two intraoperative fra... |
0 | Managing bone loss in men with locally advanced prostate cancer receiving androgen deprivation therapy | MSTS 2018 - Femur Mets and MM | Purpose: We reviewed the pathogenesis, diagnosis, prevalence, prevention and treatment of bone loss in patients with nonmetastatic prostate cancer receiving androgen deprivation therapy. Materials and Methods: Using PubMed® we performed a comprehensive literature search to identify articles on bone mineral density los... |
0 | Wheels-in-line roller skating injuries | Distal Radius Fractures | Injuries sustained by patients using wheels-in-line roller skates were reviewed in a survey of 57 cases collected by the Roosevelt Hospital Hand Service and 444 cases compiled by the Consumer Product Safety Commission. Most patients were novice skaters in the second and third decades of life. Severe distal radius fract... |
0 | Upper cervical spine injuries: age-specific clinical features | Management of Hip Fractures in the Elderly | BACKGROUND: There are few reports on the age-specific clinical features of upper cervical spine injury. To identify these age-specific changes, we reviewed 103 patients with upper cervical spine injury. METHODS: We subdivided the patients into four groups according to age: 12 patients were classified as old elderly (> ... |
0 | Comparison of oral versus sublingual piroxicam during postoperative pain management after lower third molar extraction | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | In this study, 53 patients received piroxicam, administered orally or sublingually, after undergoing removal of symmetrically positioned lower third molars, during two separate appointments. This study used a randomized, blind, cross-over protocol. Objective and subjective parameters were recorded for comparison of pos... |
0 | Lymphedema and lipedema - an overview of conservative treatment | Panniculectomy & Abdominoplasty CPG | Lymphedema and lipedema are chronic progressive disorders for which no causal therapy exists so far. Many general practitioners will rarely see these disorders with the consequence that diagnosis is often delayed. The pathophysiological basis is edematization of the tissues. Lymphedema involves an impairment of lymph d... |
0 | Relationship between aerobic capacity, injury risk and tenure for new-hire delivery drivers | DoD PRF (Psychosocial RF) | Over a 2-year study period, aerobic capacity was measured at time of hire for 1419 delivery drivers. Injury experience and tenure were then monitored for these new-hires during that same period. Number of strain injuries, time to first strain and time to termination were regressed on aerobic capacity adjusting for tenu... |
0 | Is the prevalence of the medication-related osteonecrosis of the jaws underestimated, evaluation in oncological and non-oncological disease | MSTS 2018 - Femur Mets and MM | OBJECTIVES: The purpose of this study was to evaluate the prevalence of medication-related osteonecrosis of the jaw in Slovak population and compare the literature findings, whether the prevalence of MRONJ is underestimated.
BACKGROUND: Antiresorptive drugs significantly increase quality of life, although during therap... |
0 | Osteochondritis dissecans of the lateral femoral condyle following total resection of the discoid lateral meniscus | AMP (Acute Meniscal Pathology) | PURPOSE: The purpose of this study was to describe the clinical presentation of 6 athletically active children with symptomatic osteochondritis dissecans (OCD) of the lateral femoral condyle following total resection for a torn discoid lateral meniscus and to discuss its cause.
TYPE OF STUDY: Case series.
METHODS: Six ... |
0 | Compartment syndrome after pressurized infusion | DOD - Acute Comp Syndrome CPG | We report two cases of compartment syndrome caused by extravasation of infused fluids and suggest a rationale for management and treatment based upon slit catheter monitoring of pressure in the compromised compartments. |
0 | Mid-term results of large diameter heads on cross-linked polyethylene liners in total hip replacement | PJI DX Updated Search | BACKGROUND: Highly cross-linked polyethylene liners in total hip replacement (THR) have allowed the use of larger diameter femoral heads. Larger heads allow for increased range of motion, decreased implant impingement, and protection against dislocation. The purpose of this study is to assess the clinical and radiograp... |
1 | Clinical Management in Early OA | PRP (Platelet-Rich Plasma) | Knee osteoarthritis affects an important percentage of the population throughout their life. Several factors seem to be related to the development of knee osteoarthritis including genetic predisposition, gender, age, meniscal deficiency, lower limb malalignments, joint instability, cartilage defects, and increasing spo... |
0 | Could the bone mineral density (T-score) be correlated with the Raman spectral features of keratin from women's nails and be used to predict osteoporosis? | Hip Fx in the Elderly 2019 | Osteoporosis is a disease with great importance in current public health due to the associated risk of fracture; therefore, a rapid and accurate diagnosis becomes increasingly important. Recent literature has described a possible relationship between the changes in the organic phase of bone and the changes in nail kera... |
1 | Comparison of the Clinical Effectiveness of Single Versus Multiple Injections of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis | PRP (Platelet-Rich Plasma) | Background: Reports have concluded that platelet-rich plasma (PRP) is an effective and safe biological approach in the treatment of knee osteoarthritis (OA). However, no consensus has been established regarding the number of injections required to observe a therapeutic effect.
Purpose: To compare the clinical effective... |
0 | Complications related to sedation and anesthesia for interventional pain therapies | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Aim. The use of sedation with invasive pain management procedures is increasingly prevalent. This paper discusses the inherent risks associated with sedation that is too deep as well as general anesthesia for these procedures. Methods. This article provides numerous illustrations of the risks associated with sedation f... |
0 | Implementation of locking compression plate together with intramedullary fibular graft in atrophic type humeral nonunions | DoD SSI (Surgical Site Infections) | Objective: This study aims to report the results of locking compression plate along with intramedullary fibular graft that was implemented in patients with the diagnosis of nonunion of humerus diaphysis. Materials and methods: Five patients, operated between 2000 and 2009 for atrophic type nonunion of humeral diaphysis... |
1 | Time to peak torque and acceleration time are altered in male patients following traumatic shoulder instability | Trial Systematic Review Project | Background: Numerous authors have evaluated the strength of the rotator cuff muscles in patients with shoulder instability. However, only limited data are available with regard to neuromuscular control in patients with traumatic anterior shoulder instability, in particular at 90° of abduction. This study was designed t... |
0 | Knee Joint Distraction Compared with High Tibial Osteotomy and Total Knee Arthroplasty: Two-Year Clinical, Radiographic, and Biochemical Marker Outcomes of Two Randomized Controlled Trials | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Both, knee joint distraction (KJD) and high tibial osteotomy (HTO) are joint-preserving surgeries that postpone total knee arthroplasty (TKA) in younger osteoarthritis (OA) patients. Here we evaluate the 2-year follow-up of KJD versus TKA and KJD versus HTO in 2 noninferiority studies.
DESIGN: Knee OA patien... |
0 | Case report of bone mastocytosis: Total hip arthroplasty for osteoarthritis and open reduction for condylar fracture of the knee | Surgical Management of Osteoarthritis of the Knee CPG | A 72-year-old woman was admitted in 1984 for painful protrusive osteoarthritis of the left hip diagnosed as systemic mastocytosis with bone lesions and clinical features of intestinal malabsorption but no clinical skin lesion. The total hip replacement, refused in a first step because of the bone pathology, was carried... |
0 | Patellofemoral arthroplasty: the third compartment | Surgical Management of Osteoarthritis of the Knee CPG | Isolated arthritis on the patellofemoral articulation has received minimal attention in the past. It is now recognized to be relatively common, especially in women. Treatment alternatives such as patellectomy, unloading osteotomies, debridement, and cartilage transplant have not offered long-term sustainable benefits. ... |
0 | Intentional nonadherence due to adverse symptoms associated with antiretroviral therapy | Reduction Mammoplasty for Female Breast Hypertrophy | Objective: To estimate the frequency and possible predictors of patient-mediated intentional alterations in antiretroviral medication regimens in direct response to symptoms associated with antiretroviral therapy use. Design: Cross-sectional survey of a population-based dynamic cohort of antiretroviral recipients in a ... |
0 | Heparin-induced thrombocytopenia: a complication of thromboprophylaxis | Management of Hip Fractures in the Elderly | Heparin is a drug widely used for thromboprophylaxis or treatment in many clinical situations. However, it can cause serious adverse effects, including thrombocytopenia, which is a potentially life-threatening condition. Unfortunately, heparin-induced thrombocytopenia is generally under-recognised and under-diagnosed. ... |
0 | Acute Compartment Syndrome: Update on Diagnosis and Treatment | DOD - Acute Comp Syndrome CPG | Acute compartment syndrome can have disastrous consequences. Because unusual pain may be the only symptom of an impending problem, a high index of suspicion, accurate evaluation, and prophylactic treatment will allow the physician to intervene in a timely manner and prevent irreversible damage. Muscles tolerate 4 hours... |
0 | Glenohumeral relationships: subchondral mineralization patterns, thickness of cartilage, and radii of curvature | Glenohumeral Joint OA | Subchondral mineralization represents the loading history of a joint and can be measured in vivo using computed tomography osteoabsorptiometry. Different mineralization patterns in the glenohumeral joint have been explained by the principle of physiologic incongruence. We sought to support this explanation by measureme... |
0 | Pattern noise (PANO): a new automated functional glaucoma test | Upper Eyelid and Brow Surgery | PURPOSE: To present a newly developed visual field device (pattern noise: PANO) designed to be sensitive to glaucoma defects, cost-effective, material-practical and easy to repair and therefore particularly suited for low-income countries, where glaucoma can be highly prevalent (e.g. sub-Saharan Africa). METHODS: This ... |
1 | The salvage of open grade IIIB ankle and talus fractures | DoD LSA (Limb Salvage vs Amputation) | Between 1983 and 1989, 11 open grade IIIB ankle or talus fractures were treated according to protocol including debridement, temporary placement of antibiotic beads, soft tissue coverage (including seven free vascular tissue transfers), intravenous antibiotics and fusion using an anterior plate, and bone graft. All pat... |
0 | Compressive neuropathy in the upper limb | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Entrampment neuropathy or compression neuropathy is a fairly common problem in the upper limb. Carpal tunnel syndrome is the commonest, followed by Cubital tunnel compression or Ulnar Neuropathy at Elbow. There are rarer entities like supinator syndrome and pronator syndrome affecting the Radial and Median nerves respe... |
0 | Cost analysis of dental services needed before hematopoietic cell transplantation | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | OBJECTIVE: Streptococcal bacteremia occurs during hematopoietic cell transplantation (HCT), and treatment of active oral disease may reduce this risk. The objective of this study was to determine the type, number, and costs of pre-transplantation dental procedures in this population. STUDY DESIGN: Data were collected r... |
0 | Wrist position in closed reduction of fractured carpal scaphoid. An experimental observation | Distal Radius Fractures | Experimental observation on the relation between the apposition of scaphoid fracture surfaces and wrist position showed that fracture reduction could be achieved when the wrist was placed in a position from 15 degrees radial deviation to 15 degrees ulnar deviation provided that the wrist assumed certain amount of exten... |
0 | Results of open reduction internal fixation versus percutaneous iliosacral screw fixation for unstable pelvic ring injuries: retrospective study of 36 patients | DoD SSI (Surgical Site Infections) | Introduction: Surgical stabilization of posterior pelvic ring fractures can be achieved by closed reduction and percutaneous fixation (CRPF) or by open reduction and internal fixation (ORIF). The aim of the present study is to compare the clinical results of both methods. Material and methods: Medical records of 36 pat... |
0 | Are continuous femoral nerve catheters beneficial for pain management after operative fixation of tibial plateau fractures? A randomized trial | AAHKS (9/10) Regional Nerve Blocks | Purpose: Continuous femoral and sciatic nerve blocks diminish pain and narcotic requirements after total knee arthroplasty. While sciatic block is contraindicated after plateau fractures in order to allow clinical evaluation of compartment syndrome, femoral nerve blocks may help in pain management as this block affects... |
0 | Antibiotic prophylaxis of infective endocarditis in dentistry: clinical approach and controversies | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | PURPOSE: Infective endocarditis (IE) in high-risk patients is a potentially severe complication which justifies the administration of antibiotics before invasive dental treatment. This literature review presents the current guidelines for antibiotic prophylaxis and discusses the controversial aspects related to the ant... |
0 | Epidermal growth factor receptor is associated with the onset of skeletal related events in non-small cell lung cancer | DoD PRF (Psychosocial RF) | Background: Bone metastasis and skeletal related events (SREs) are common in non-small cell lung cancer (NSCLC). Patients with mutant epidermal growth factor receptor (EGFR) could benefit from tyrosine kinase inhibitors (TKIs). However, it is unclear whether SRE is influenced by EGFR status. We aimed to evaluate the co... |
0 | Falls in the elderly | Management of Hip Fractures in the Elderly | Most falls in older people can be prevented or reduced in frequency if clinicians first begin to view the fall as symptomatic of an underlying problem and, second, perform comprehensive assessments to uncover a multitude of medical, psychological, and environmental factors that may cause falling |
0 | Variability in the disposition of ibuprofen enantiomers in osteoarthritis patients | Management of Hip Fractures in the Elderly | The pharmacokinetics of the enantiomers of ibuprofen have been investigated following oral administration of 300 or 600 mg of racemic ibuprofen four times daily to 45 patients with osteoarthritis. Fifteen of these patients also received single doses of 300 or 600 mg of racemic ibuprofen. Serum concentrations of R- and ... |
0 | Correlates of psychological distress following armed robbery | DoD PRF (Psychosocial RF) | Although mental health professionals have long been aware of the impact of traumatic events, it was not until 1980 that the term posttraumatic stress disorder (PTSD) was introduced into the DSM-III. Since then, one major goal of research has been to identify factors associated with distress following trauma; as yet, fe... |
0 | BIS and Entropy in the elderly | Management of Hip Fractures in the Elderly | The interaction of many poorly defined, physiological, pharmacological, and pathological factors make titration of general anaesthesia in the elderly difficult. There may be a potential clinical benefit using the processed electroencephalogram (EEG) to monitor hypnotic level in this population. We prospectively studied... |
1 | A comparison of sartorius versus quadriceps stimulation for femoral nerve block: a prospective randomized double-blind controlled trial | AAHKS (9/10) Regional Nerve Blocks | BACKGROUND: Femoral nerve block is widely used for regional anesthesia and analgesia in many lower limb operations. Peripheral nerve stimulation of the femoral nerve may elicit 1 of 2 responses: contraction of the sartorius muscle through stimulation of its muscular branch or contraction of the quadriceps muscle throug... |
1 | The Effect of Drains and Compressive Garments Versus Progressive Tensioning Sutures on Seroma Formation in Abdominoplasty | Panniculectomy & Abdominoplasty CPG | Seroma is a common problem following abdominoplasty surgery. Both compressive garments with drains and progressive tension sutures have their advocates to minimise seroma formation. This is a retrospective study in which patients underwent an identical surgical procedure, except for use of drains and garments in compar... |
0 | Solvent-free fabrication of micro-porous polyurethane amide and polyurethane-urea scaffolds for repair and replacement of the knee-joint meniscus | AMP (Acute Meniscal Pathology) | New porous polyurethane urea and polyurethane amide scaffolds for meniscal reconstruction have been developed in a solvent-free process. As soft segments, copolymers of 50/50 L-lactide/epsilon-caprolactone have been used. After terminating the soft segment with diisocyanates, chain extension was performed with adipic a... |
1 | Comparison between eyelid indices of ptotic eye and normal fellow eye in patients with unilateral congenital ptosis | Upper Eyelid and Brow Surgery | PURPOSE: To evaluate the relationship between levator muscle function (LMF) and other eyelid parameters in the normal and affected eyes of patients with unilateral congenital ptosis. METHODS: This study includes subjects with unilateral congenital upper lid ptosis who were referred for operation over a 2-year period. P... |
0 | Effects of 8-bromoadenosine 3':5'-cyclic monophosphate on proteolytic enzymes, adhesiveness and lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells | MSTS 2018 - Femur Mets and MM | Treatment of cloned low-metastatic Lewis lung carcinoma cells (P-29) with dimethylsulfoxide or butyric acid resulted in enhancement of their lung-colonizing ability. This was accompanied with increases in cathepsin B activity, the production of plasminogen activator, and adhesiveness, mainly heterotypic adhesion (adhes... |
0 | Thumb reconstruction by micro-vascular techniques | DoD LSA (Limb Salvage vs Amputation) | Sixty-three patients with thumb reconstruction by total or partial toe transfer have been reviewed. Mean age was 25 years. Males (84%) and manual workers (76%) dominated the series. The rate of failure was 3%. Second toe transfer gave a functionally acceptable thumb with 10 mm two point discrimination, 59% of strength ... |
1 | Effects of a diabetes-specific care model for hip fractured older patients with diabetes: A randomized controlled trial | Hip Fx in the Elderly 2019 | OBJECTIVES: To examine the effects of a diabetes-specific care model for hip fractured elderly with diabetes mellitus (DM).
METHODS: A randomized controlled trial was implemented in a 3000-bed medical center in northern Taiwan. Older adults (age>=60) with DM who had hip-fracture surgery (N=176) were recruited and rando... |
1 | The role of blood cultures in the acute evaluation of postoperative fever in arthroplasty patients | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | The use of blood cultures to work up fever in postarthroplasty patients was studied retrospectively. Four hundred fifty-three patients done consecutively with a diagnosis-related group 209 discharge diagnosis were studied. One hundred patients (22%) had blood cultures drawn for fever greater than 101 degrees F. Specifi... |
0 | Acellular Dermal Matrix Reduces Myofibroblast Presence in the Breast Capsule | Acellular Dermal Matrix | BACKGROUND: Capsular contracture remains a common complication after implant-based breast reconstruction. Previous work has suggested that the use of acellular dermal matrix (ADM) reduces the rate of capsular contracture, though little is understood about the underlying mechanism. As myofibroblasts are believed to be t... |
0 | Family, socioeconomic status and health services: Clues to health care in diabetic patients with lower limb amputations in Andalusia. A qualitative study | DoD LSA (Limb Salvage vs Amputation) | Aim: To examine the experience of diabetic care in patients undergoing lower limb amputation. Design: A qualitative study using the phenomenological approach. Setting: Cadiz Health District. Participants: A total of 16 patients (11 men and 5 women) diagnosed with diabetes mellitus type 2 and with non-traumatic lower li... |
0 | Association of low birth weight and preterm birth with the incidence of knee and hip arthroplasty for osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | Objectives: Low birth weight (LBW) and preterm birth have been associated with adverse adult outcomes including hypertension, insulin resistance, cardiovascular disease and reduced bone mass. It is unknown whether LBW and preterm birth affect the risk of osteoarthritis (OA). This study aims to examine whether LBW and p... |
0 | Metabolomic and Lipidomic Profiling of Preoperative CSF in Elderly Hip Fracture Patients With Postoperative Delirium | Hip Fx in the Elderly 2019 | Objective: To investigate dysregulated molecules in preoperative cerebrospinal fluid (CSF) of elderly hip fracture patients with postoperative delirium (POD), in order to identify potential pathological mechanisms and biomarkers for pre-stage POD.
Materials and Methods: This nested case control study used untargeted me... |
0 | Computed tomography of knee injuries | AMP (Acute Meniscal Pathology) | The knee is the largest and most complex joint in the body and a wide variety of bone and soft tissue injuries are seen in the knee. Trauma to the knee can result in injury to the bone, articular cartilage, meniscus and ligaments. Fractures of the proximal tibia, particularly those that extend into the knee joint, are ... |
0 | Medial epicondyle fractures of the humerus: how to evaluate and when to operate | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | The fundamental principles of fracture care apply to medial epicondyle fractures in that the goals of treatment are to obtain fracture healing and to promote a return of appropriate motion, strength, and stability. Recent studies have revealed limitations of some classically described evaluation methods and have reveal... |
0 | Associations of cardiovascular risk factors, carotid intima-media thickness and manifest atherosclerotic vascular disease with carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND: The role of atherosclerosis in carpal tunnel syndrome (CTS) has not previously been addressed in population studies. The aim of this study was to investigate the associations of cardiovascular risk factors, carotid artery intima-media thickness (IMT), and clinical atherosclerotic diseases with CTS. METHODS:... |
0 | Treatment of recurrent compressive neuropathy of peripheral nerves in the upper extremity with an autologous vein insulator | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | The treatment of entrapment neuropathy in the upper extremity with surgical decompression has generally provided good results. Recurrence of symptoms, however, is not uncommon and its management is both challenging and difficult. Nineteen patients with recurrent carpal tunnel and cubital tunnel syndrome were treated wi... |
1 | Double contrast arthrography of the knee | AMP (Acute Meniscal Pathology) | The author's experience with 280 double contrast knee arthrograms is presented. The accuracy of the procedure in 101 operated cases was 100 percent for normal menisci and 88 percent for abnormal. It is suggested that arthrography can be regarded as an integral part of the investigation of any knee in which a serious me... |
0 | Midfoot crush injuries | DOD - Acute Comp Syndrome CPG | Treatment of midfoot injuries is surgical or nonsurgical, depending on the injury, the location, and the extent of the injury. Minor injuries usually heal with casting or bracing, whereas more unstable injuries typically need surgery for stability. Whether the injury is in a weight-bearing portion of the foot is also a... |
0 | Integrity of the first metatarsophalangeal joint: A biomechanical analysis | DoD LSA (Limb Salvage vs Amputation) | Five fresh-frozen cadaver feet obtained from traumatic amputations were tested during hyperdorsiflexion stress of the first metatarsophalangeal joint. Three different types of injury were observed: (1) rupture of the capsule proximal to the sesamoids, (2) rupture of the plantar plate distal to the sesamoids, and (3) ru... |
0 | Analysis of Bony and Internal Organ Injuries Associated With 26,357 Adult Femoral Shaft Fractures and Their Impact on Mortality | Pediatric Diaphyseal Femur Fractures 2020 Review | The spectrum of injuries associated with femoral shaft fractures and those injuries' association with mortality have not been well delineated previously. Patients in the National Trauma Data Bank who presented with femoral shaft fractures from 2011 to 2012 were analyzed in 3 age groups (18-39, 40-64, and 65+ years). Fo... |
0 | Does Chronic Corticosteroid Use Increase Risks of Readmission, Thromboembolism, and Revision After THA? | AAHKS (2) Corticosteroids | BACKGROUND: Systemic corticosteroids are commonly used to treat autoimmune and inflammatory diseases, but they can be associated with various musculoskeletal problems and disorders. There currently is a limited amount of data describing the postoperative complications of THA associated specifically with chronic cortico... |
1 | Animation Deformity in Postmastectomy Implant-Based Reconstruction | Acellular Dermal Matrix | Despite increasing interest in prepectoral implant-based reconstruction to avoid animation deformity (AD), the prevalence of this deformity and patient attitudes toward it have not been extensively studied. The purpose of this study was to report on AD in the breast reconstruction population and identify those at highe... |
0 | Long-term followup of the bone-ingrowth Ortholoc knee system without a metal-backed patella | Surgical Management of Osteoarthritis of the Knee CPG | Between June 1981 and January 1984, 265 Ortholoc-I femoral and tibial components were implanted using bone-ingrowth technique in 202 patients. Five knees (five patients) were lost to followup and 66 knees were excluded because the patients died, leaving 184 knees (165 patients) with 15 to 18 years followup. One knee lo... |
1 | Usefulness of prophylactic antibiotics in preventing infection after internal fixation of closed hand fractures | DoD SSI (Surgical Site Infections) | Prophylactic antibiotics (PA) have been shown to be ineffective in reducing the incidence of surgical site infection (SSI) in clean wounds associated with elective surgery of the hand. Routine administration of PA for internal fixation of hand fractures is a subject that has been scarcely studied. We hypothesized that ... |
0 | The development of risk assessment models for carpal tunnel syndrome: a case-referent study | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | The present study developed risk assessment models for carpal tunnel syndrome (CTS) which can provide information of the likelihood of developing CTS for an individual having certain personal characteristics and occupational risks. A case-referent study was conducted consisting of two case groups and one referent group... |
0 | Vascular access for hemodialysis: Current practice in Vietnam | Panniculectomy & Abdominoplasty CPG | A well-functioning vascular access is a mainstay to perform an efficient hemodialysis procedure, which directly affects the quality of life in hemodialysis patients. We use three main types of access: native arteriovenous fistula, arteriovenous graft, and central venous catheter. Arteriovenous fistula remains the first... |
0 | Translation and validation of the Oxford-12 Item Knee Score for use in Sweden | Surgical Management of Osteoarthritis of the Knee CPG | The Oxford-12 Item Knee Score is a recently developed and validated patient-completed outcome measure designed specifically for use with knee arthroplasty in the United Kingdom. We have translated this questionnaire into Swedish and tested the validity and reliability of the translated version in a cross-sectional stud... |
0 | Penicillin compared with other advanced broad spectrum antibiotics regarding antibacterial activity against oral pathogens isolated from odontogenic abscesses | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Objectives: We examined the spectrum of oral pathogens found in odontogenic abscesses and their susceptibility to penicillin as well as to amoxicillin with clavulanic acid, doxycycline, clindamycin and moxifloxacin. The in vitro results were compared with clinical observations. Patients and methods: One hundred and eig... |
0 | Update on the treatment of granulomatosis with polyangiitis (Wegener's) | Reconstruction After Skin Cancer | Granulomatosis with polyangiitis (Wegener's) (GPA), formerly known as Wegener's granulomatosis, is a systemic vasculitis characterized by involvement of the upper airways, lungs, and kidneys. GPA shares many features with microscopic polyangiitis (MPA), so much so that recent trials have included both vasculitides. Thi... |
0 | The critical role of the bone microenvironment in cancer metastases | MSTS 2018 - Femur Mets and MM | Bone metastatic disease is a late-stage event of many common cancers, such as those of prostate and breast. It is incurable and causes severe morbidity. Tumor and bone interact in a vicious cycle, where tumor-secreted factors stimulate bone cells, which in turn release growth factors and cytokines that act back on the ... |
0 | Differences in risk factors for neurophysiologically confirmed carpal tunnel syndrome and illness with similar symptoms but normal median nerve function | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Objectives To explore whether neurophysiologically confirmed carpal tunnel syndrome (CTS) has different risk factors from sensory symptoms in the hand that occur in the absence of impaired median nerve conduction. Methods We compared 475 patients with neurophysiologically confirmed (NP+ve) CTS, 409 patients investigate... |
0 | C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study | Surgical Management of Osteoarthritis of the Knee CPG | OBJECTIVE: To explore the relationships between C-reactive protein (CRP), metabolic syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective study. METHODS: A population-based cohort (n=5171, mean age 57.5+/-5.9 years) was examined between 1991 and 1994. Data was collected on lifestyle h... |
0 | Medial mini-open versus percutaneous pin fixation for type III supracondylar fractures in children | DoD SSI (Surgical Site Infections) | BACKGROUND: The present objective was to compare medial mini-open and percutaneous treatment of pediatric supracondylar fractures according to fluoroscopy time, duration of surgery, and iatrogenic ulnar nerve injury. METHODS: A total of 104 Gartland type III supracondylar humerus fractures were prospectively evaluated ... |
0 | Health care professionals' readiness for an interprofessional orthogeriatric unit: A cross-sectional survey | Hip Fx in the Elderly 2019 | An assessment of readiness for change can set the stage for the implementation by providing information regarding staff members' beliefs and attitudes prior to an organizational change. We conducted a cross-sectional survey to assess readiness for change (N = 113 employees) in a hospital on the verge of implementing an... |
0 | Multiple myeloma and chronic lymphocytic leukemia | MSTS 2018 - Femur Mets and MM | Much progress has been made in delineating the pathogenesis of multiple myeloma and chronic lymphocytic leukemia. The cell of origin in both diseases has been better defined, which has led to important clinical treatments. For myeloma, reduction of tumor burden in autografts has been accomplished and been associated wi... |
0 | Bacterial infections associated with allogenic bone transplantation | DoD SSI (Surgical Site Infections) | Background/Aim. Bone allografts are frequently used in or-thopedic reconstructive procedures carrying a high risk for re-cipients. To assess the nature and frequency of allograft con-tamination and associated surgical infection the case records from our institutional bone bank were reviewed. Methods. We retrospectively... |
0 | Nerve entrapments associated with postmastectomy lymphedema | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Ninety females underwent mastectomy for breast cancer and were thereafter investigated to determine whether nerve entrapments were responsible for some of the disabling symptoms in their arms. The majority of these patients suffered from fullness (edema), numbness, paraesthesia, weakness and pain of the arm on the mast... |
0 | Effects of chlorhexidine-fluoride mouthrinses on viability, acidogenic potential, and glycolytic profile of established dental plaque | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Inhibition of dental plaque acidogenicity by chlorhexidine (CHX) mouthrinses has been ascribed to a long-lasting bacteriostatic effect due to binding of CHX to oral surface structures combined with a slow release rate from the binding sites. The present aims were to study the effects of CHX-containing mouthrinses on th... |
0 | Technical protocol for infiltration of the humeral joint in a rat animal model | Glenohumeral Joint OA | Studies exist which confirm that the rat is the most appropriate model for assessing the glenohumeral (shoulder) joint and its pathologies, such as osteoarthritis and disease of the tendons of the rotator muscles in the joint. However there are no recorded studies of osteoarthritis induced in the Glenohumeral Joint (GJ... |
0 | Trabecular bone modeling and subcapital femoral fracture | Management of Hip Fractures in the Elderly | Fragility fractures, including neck of femur fractures, result from reductions in the amount, quality and architecture of bone. The aim of this study was to compare the cancellous bone structure, and static indices of bone turnover, in female patients who had sustained fragility fracture at the femoral neck, with age-m... |
0 | Increased incidence of hip fractures in dialysis patients with low serum parathyroid hormone | Management of Hip Fractures in the Elderly | To study the complications of renal osteodystrophy in patients with end-stage renal disease, we reviewed the incidence of hip fractures in our outpatient dialysis population from 1988 to 1998. One thousand two hundred seventy-two patients were treated for a total of 4,039 patient-years; 56 hip fractures were documented... |
0 | Hip protectors for preventing hip fractures in older people | Management of Hip Fractures in the Elderly | BACKGROUND: Hip fracture in older people usually results from a fall on the hip. Hip protectors have been advocated as a means to reduce the risk of sustaining a hip fracture. OBJECTIVES: To determine if external hip protectors reduce the incidence of hip fractures in older people following a fall. SEARCH STRATEGY: We ... |
0 | Emergency physician-performed ultrasound-guided nerve blocks in proximal femoral fractures provide safe and effective pain relief: a prospective observational study in The Netherlands | Hip Fx in the Elderly 2019 | Background: The treatment of acute pain in the emergency department is not always optimal. Peripheral nerve blocks using â??blindâ? or nerve stimulator techniques have substantial disadvantages. Ultrasound-guided regional anesthesia may provide quick, safe, and effective pain relief in patients with proximal femoral f... |
0 | Recent advances in the surgical management of necrotizing pancreatitis | DoD - ACS - Interrater Reliability | PURPOSE OF REVIEW: To summarize advances and new concepts in the surgical management of necrotizing pancreatitis published within the past year with emphasis on the evolving importance of the recognition of abdominal compartment syndrome as a significant contributor to early development of organ failure.
RECENT FINDING... |
1 | Acellular dermal matrices in breast surgery: tips and pearls | Acellular Dermal Matrix | Acellular dermal matrices (ADMs) have been used for postmastectomy breast reconstruction, primary and secondary breast augmentation, and reduction mammaplasty. In postmastectomy breast reconstruction, ADMs can be used to either create an implant pocket in single-stage reconstruction or to create the inferolateral porti... |
0 | Salter-harris type III fracture-dislocation of the proximal humerus | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Salter-Harris type III fractures of the proximal humerus are rare injuries. We report a Salter-Harris type III anterior fracture-dislocation of the proximal humerus in a 10-year-old boy that was open reduced and internally stabilized. A hone scan performed during the initial hospitalization and at 2-year follow-up reve... |
1 | Limited diagnostic accuracy of magnetic resonance imaging and clinical tests for detecting partial-thickness tears of the rotator cuff | Trial Systematic Review Project | INTRODUCTION: The reliable diagnosis of partial-thickness tears of the rotator cuff is still elusive in clinical practise. Therefore, the purpose of the study was to determine the diagnostic accuracy of MR imaging and clinical tests for detecting partial-thickness tears of the rotator cuff as well as the combination of... |
0 | NF-KB activity is reduced by inosderived no in human chondrocytes: Contribution to sustained low grade inflammation in osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | NF-kB mediates important chondrocyte inflammatory and catabolic responses that ultimately lead to cartilage destruction, the hallmark of osteoarthritis (OA). This work aimed at identifying the role of the neuronal and inducible Nitric Oxide Synthases (nNOS and iNOS, respectively) as sources of NO in normal and OA human... |
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