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Treatment of acute injuries of the triangular fibrocartilage complex associated with distal radioulnar joint instability
Distal Radius Fractures
One hundred thirty patients who had an injury of the triangular fibrocartilage complex (TFCC) with distal radioulnar joint (DRU) instability were treated operatively. The TFCC injury with DRUJ instability occurred as an isolated lesion in 20. After appropriate fracture stabilization, 86 patients were treated with close...
0
Management of chronic pain in whiplash injury
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
We investigated the response of chronic neck and shoulder pain to decompression of the carpal tunnel in 38 patients with whiplash injury. We also determined the plasma levels of substance P (SP) and calcitonin gene-related peptide (CGRP), which are inflammatory peptides that sensitise nociceptors. Compared with normal ...
0
Bone Mass and Strength and Fall-Related Fractures in Older Age
Distal Radius Fractures
Introduction: Low bone mineral density is a risk factor for fractures. The aim of this follow-up study was to assess the association of various bone properties with fall-related fractures., Materials and Methods: 187 healthy women aged 55 to 83 years at baseline who were either physically active or inactive were follow...
0
Endodontic failures--changing the approach
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The underlying reason for endodontic failures is almost invariably due to bacterial infection. The bacteria may be situated within a previously missed or uninstrumented portion of a root canal, infiltrate via a leaky coronal restoration and root filling, or cause contamination from an extra-radicular infection. Managem...
0
A decade of reversal: An analysis of 146 contradicted medical practices
AAHKS (2) Corticosteroids
Objective: To identify medical practices that offer no net benefits. Methods: We reviewed all original articles published in 10 years (2001-2010) in one high-impact journal. Articles were classified on the basis of whether they addressed a medical practice, whether they tested a new or existing therapy, and whether res...
0
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture
Management of Hip Fractures in the Elderly
The abundance of a preselection of transcripts involved in inflammation, immunosenescence and stress response was compared between PBMC of healthy aged donors and aged patients in acute phase of heart failure and at recovery. This study identified 22 transcripts differentially abundant in acute phase of heart failure v...
0
Total knee arthroplasty for rheumatoid arthritis patients with large tibial condyle defects
Surgical Management of Osteoarthritis of the Knee CPG
PURPOSE: To review clinical results of total knee arthroplasty (TKA) in rheumatoid arthritis (RA) patients with large bone defects of the tibial condyle. METHODS: Records of 33 knees in 27 women and 3 men aged 44 to 80 (mean, 63.6) years who underwent primary TKA for RA with large tibial bone defects were reviewed. 16 ...
1
Observation of single spinal anesthesia by 25G needle puncture through a lateral crypt for hip surgery in elderly patients
Hip Fx in the Elderly 2019
BACKGROUND: Lumbar spine hyperosteogeny and ligament calcification are common in the elderly and anesthesia puncture through the conventional approach is difficult in this age group, and repeated puncture can increase the risk of spinal hematoma and nerve injury. This study aimed to observe the feasibility and safety o...
0
Serum ACE for sarcoidosis is not such an ACE test
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Background A serum angiotensin-converting enzyme (ACE) level can be elevated in patients with active sarcoidosis. This association was first described Dr Lieberman in 1975 (1). He looked at serum ACE levels in 200 control patients and 200 patients with chronic lung disease. He found that 15 of 17 patients with active s...
0
Maternal Height and Infant Body Mass Index Are Possible Risk Factors for Developmental Dysplasia of the Hip in Female Infants
Developmental Dysplasia of the Hip 2020 Review
Developmental dysplasia of the hip (DDH) is a wide-spectrum disease with a multifactorial etiology and, despite its prevalence, no definitive etiology has yet been established. The aim of this study was to investigate new risk factors for DDH by evaluating newly defined potential risk factors. A total of 71 infants wer...
0
Ketamine-assisted intravenous sedation with midazolam: benefits and potential problems
Panniculectomy & Abdominoplasty CPG
A review of 134 cases of ketamine-induced intravenous sedation was undertaken. It was concluded that (1) whereas properly titrated midazolam with low-dose ketamine (0.5 mg/kg) can provide almost complete absence of behavioral problems and complete analgesia, transient oxygen desaturation may be seen, and (2) the induct...
1
Resilience, traumatic brain injury, depression, and posttraumatic stress among Iraq/Afghanistan war veterans
DoD PRF (Psychosocial RF)
OBJECTIVE: We examined the prospective influence of the resilient, undercontrolled, and overcontrolled personality prototypes on depression and posttraumatic stress disorder (PTSD) symptoms among Iraq/Afghanistan war veterans. After accounting for the possible influence of combat exposure, we expected that the resilien...
0
Risk factors for osteoporosis and fracture in patients attending rheumatology outpatient clinics
Management of Hip Fractures in the Elderly
Background: Bone mineral density (BMD) using dual energy X-ray absorptiometry (DXA) scanning is the best predictor of osteoporotic fracture but may not be cost effective for all patient groups. Risk factors (RF) other than BMD may be useful for fracture prediction. Aim: To assess the prevalence of RF for osteoporosis (...
0
Comparative study of skin closure in hip surgery
Management of Hip Fractures in the Elderly
A prospective, randomized controlled study was performed to compare skin staplers for closure of skin following hip surgery. Patients were randomized to have their skin closed with either continuous subcuticular non-absorbable polypropylene 'prolene' suture (33 patients) or metal skin staples (Autosuture 'Premium' or D...
0
Ultrasound-guided procedures to treat periarticular calcifications
Pediatric Supracondylar Humerus Fracture 2020 Review
Calcific tendinitis of the rotator cuff is one of the most common causes of shoulder pain, having an impact on patientsâ?? daily and professional activities. After failure of first-line treatments (analgesics/NSAIDs, physiotherapy, corticosteroid injection), a percutaneous procedure to remove the calcification under ul...
0
Animal model of implant capsular contracture: effects of chitosan
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: The mechanism(s) responsible for breast capsular contracture (CC) remain unknown, but inflammatory pathways play a role. Various molecules have been attached to implant shells in the hope of modifying or preventing CC. The intrinsic antibacterial and antifungal activities of chitosan and related oligochitos...
0
dGEMRIC as a tool for measuring changes in cartilage quality following high tibial osteotomy: a feasibility study
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: The high tibial osteotomy (HTO) is an effective strategy for treatment of painful medial compartment knee osteoarthritis. Effects on cartilage quality are largely unknown. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) enables non-invasive assessment of cartilage glycosaminogly...
0
Factors affecting long-term results after arthroscopic partial meniscectomy
AMP (Acute Meniscal Pathology)
The purpose of this study was to determine functional and radiographic changes on long-term followup of knees with isolated meniscal tears. Sixty-seven patients were evaluated retrospectively with an average of 12.2 years' followup using the scale of Tapper and Hoover. The criteria for the radiographic results were the...
0
Evaluation of arthroscopic articular cartilage biopsy for osteoarthritis of the knee
Surgical Management of Osteoarthritis of the Knee CPG
PURPOSE: Arthroscopic evaluation of the articular surface by visualization and palpation has proved to be unreliable; therefore, we investigated arthroscopically procured biopsy specimens and conventional sections by using the same histopathomorphologic techniques and compared the results for possible differences. METH...
0
A new approach in the miniminvasive treatment of fractures
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
The use of biological cement with provisory closed percutaneous Kirschner wire (K-wire) Wxation enabled the treatment of 12 patients with fractures. Within the period November 2010 - February 2011, we have treated at Saint Pantelimon Emergency Orthopaedics Clinic 12 patients using this specific method, namely: 8 humera...
0
Influence of Acetabular Shell Position and Component Design on Hip Dynamic Dislocation
Developmental Dysplasia of the Hip 2020 Review
BACKGROUND: Dislocation is a major complication following total hip arthroplasty, with risk factors such as surgical technique, implant positioning, and implant design. Literature has suggested the distance the femoral head must travel before dislocation to be a predictive factor of dislocation where smaller travel dis...
0
A new uncemented hydroxyapatite-coated femoral component for the treatment of femoral neck fractures: two-year radiostereometric and bone densitometric evaluation in 50 hips
Dental Implant Infection
Our aim in this pilot study was to evaluate the fixation of, the bone remodelling around, and the clinical outcome after surgery of a new, uncemented, fully hydroxyapatite-coated, collared and tapered femoral component, designed specifically for elderly patients with a fracture of the femoral neck. We enrolled 50 patie...
0
Internal fixation for displaced fractures of the femoral neck
Management of Hip Fractures in the Elderly
The results of meta-analysis show a revision rate of 33% for internal fixation of displaced fractures of the femoral neck, mostly because of nonunion. Osteopenia and osteoporosis are highly prevalent in elderly patients. Bone density has been shown to correlate with the intrinsic stability of the fixation of the fractu...
0
Early Morbidity but Not Mortality Increases With Surgery Delayed Greater Than 24 Hours in Patients With a Periprosthetic Fracture of the Hip
DoD SSI (Surgical Site Infections)
Background: Studies have identified a possible morbidity and mortality benefit with expedited time to surgery after a native hip fracture. This association after hip periprosthetic fractures (PPF) has been less clearly delineated. The purpose of this study is to assess the effect of time to surgery on rates of 30-day c...
0
A Comparison of Elliptical Mastectomy to Inverted-T Pattern Mastectomy in Two-Stage Prosthetic Breast Reconstruction
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: Patients with large or ptotic breasts undergoing mastectomy followed by tissue expander/implant-based reconstruction may benefit from a Wise (inverted-T) pattern reduction mammaplasty incision compared with the traditional horizontal elliptical incision. The authors compared these two groups of patients wit...
0
Culture and PCR analysis of joint fluid in the diagnosis of prosthetic joint infection
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
This prospective study compared PCR and culture techniques in the diagnosis of prosthetic joint infection (PJI). We obtained joint fluid samples (JFS; n=115) from patients who had failed total joint arthroplasty between January 2003 and June 2005; 49 were positive for PJI according to established strict criteria. JFS w...
0
Early recognition of chemical dependence
DoD PRF (Psychosocial RF)
Chemical dependence is a leading cause of morbidity and death in the United States. At least 20% of patients seen by primary care physicians in both the outpatient and inpatient setting are chemically dependent. Up to 90% of these patients go undiagnosed by their primary physicians. Chemical dependence is defined as a ...
0
Staining of demineralized cartilage. II. Quantitation of articular cartilage proteoglycan after fixation and rapid demineralization
Management of Hip Fractures in the Elderly
Safranin O in the orthochromatic form stains articular cartilage proteoglycan quantitatively in histological sections of demineralized cartilage. This was shown by scanning microdensitometry of stained sections of undemineralized and demineralized articular cartilage and by biochemical analysis of 35S labelled cartilag...
0
European Congress on Osteoporosis and Osteoarthritis, ECCEO11-IOF
SR for PM on OA of All Extremities
The proceedings contain 641 papers. The topics discussed include: the burden of fractures in France, Germany, Italy, Spain, Sweden, and the UK; bone microarchitecture assesment by high-resolution peripheral quantitative computed tomography(HR-PQCT) in healthy women; DAPS (denosumab adherence preference satisfaction): r...
1
The effect of partial lateral meniscectomy in patients > or = 60 years
AMP (Acute Meniscal Pathology)
To determine the benefit, if any, of meniscectomy in an older population, all patients > or = 60 years who underwent partial lateral meniscectomy were evaluated. Thirty-five patients (36 knees) were available for follow-up. The average patient age was 64.9 years. Patients were divided into two groups based on the degre...
1
High short-term return to sports rate despite an ongoing healing process after acute meniscus repair in young athletes
AMP (Acute Meniscal Pathology)
PURPOSE: Acute meniscus repair in young athletes is always a challenge due to the long rehabilitation process and time to return to sport (RTS). The purpose was to investigate signal alterations in short-term follow-up after acute meniscus repair on specific magnetic resonance imaging (MRI) scan sequences. It was hypot...
0
Building resistance, resilience, and recovery in the wake of school and workplace violence
DoD PRF (Psychosocial RF)
Incidents of school and workplace violence are rare but devastating events that can result in significant psychological consequences in communities. The majority of people in the United States will experience some type of traumatic event in their lifetime, but most of them will have no disruption or only transient disr...
0
Ultrasound measures of muscle thickness may be superior to strength testing in adults with knee osteoarthritis: a cross-sectional study
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Evaluation of muscle strength as performed routinely with a dynamometer may be limited by important factors such as pain during muscle contraction. Few studies have compared formal strength testing with ultrasound to measure muscle bulk in adults with knee osteoarthritis (OA). METHODS: We investigated the m...
0
Carpal tunnel syndrome in amyloidosis: Prevalence, risk factors and correlation with cardiac involvement in a large cohort of 435 consecutive patients
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Purpose: Carpal tunnel syndrome (CTS) is one of the most common clinical manifestations of TTR-related amyloidosis, both hereditary (ATTR), and wild type (senile systemic amyloidosis, SSA) and often precedes cardiac symptoms. The exact prevalence of CTS in amyloidosis however is not known. We therefore aimed to establi...
0
Lumbar facet joint osteoarthritis: a review
SR for PM on OA of All Extremities
OBJECTIVES: The facet joints (FJ) can be a potentially important source of symptoms because of the high level of mobility and load forces, especially in the lumbar area. We reviewed the anatomy, biomechanics, and possible sources of pain of the FJ, natural history, and risk factors of lumbar FJ osteoarthritis and brief...
0
Evaluation of Meniscal Regeneration in a Mini Pig Model Treated With a Novel Polyglycolic Acid Meniscal Scaffold
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Meniscal injury is a severe impediment to movement and results in accelerated deterioration of the knee joint. PURPOSE: To evaluate the effect of a novel meniscal scaffold prepared from polyglycolic acid coated with polylactic acid/caprolactone on the treatment of meniscal injury in a mini pig model. STUDY ...
0
Cementless total hip arthroplasty in renal transplant patients
AAHKS (2) Corticosteroids
Twenty-seven cementless total hip arthroplasties were performed in 17 steroid-dependent renal transplant patients. The average age at operation was 39 years, and the average daily dose of prednisone was 10.9 mg. At a mean of 48 months post-surgery, all patients had good to excellent hip ratings on clinical examination ...
1
Hospital management preparedness tools in biological events: A scoping review
Coronavirus Disease 2019 (COVID-19)
INTRODUCTION: The objective of the present study was to systematically review the current research knowledge on hospital preparedness tools used in biological events and factors affecting hospital preparedness in such incidents in using a scoping review methodology. MATERIALS AND METHODS: The review process was conduct...
0
Arthroplasty hip infection: The physician point of view
AAHKS (2) Corticosteroids
Total hip replacement is one of the most common orthopaedic surgeries, and its most frequent indication is osteoarthritis. Prosthetic Hip infection (PHI) can occur in 1 to 1.5 percent of cases. Some risk factors have been identified (modifiable or not), such as obesity, diabetes, corticosteroids, malnutrition, anemia, ...
0
Accuracy of implant alignment and early results after minimally invasive vs conventional OrthoPilot-navigated Columbus TKA
Surgical Management of Osteoarthritis of the Knee CPG
The goal of this study was to evaluate potential risks and benefits of minimally invasive vs conventional approaches in navigated total knee arthroplasty (TKA) in 50 patients. Preoperatively, no statistically significant differences between the two groups were found for deformity, range of motion (ROM), clinical scores...
0
The efficacy and safety of Calidron tablets for management of osteoporosis in Jordanian women: a randomised clinical trial
Management of Hip Fractures in the Elderly
The aim of this study was to evaluate the efficacy and safety of daily alendronate (Calidron) 5 and 10 mg for treatment and prevention of osteoporosis in postmenopausal Jordanian women. Subjects were randomly assigned to receive oral treatment with alendronate in the form of Calidron 5mg or 10 mg; or identically appear...
0
Service provision for patients with chronic pain after knee replacement: An evaluation of current practice in high volume orthopaedic centres
Surgical Management of Osteoarthritis of the Knee CPG
Background: Total knee replacement is one of the most commonly performed elective surgical procedures. The operation is usually conducted to relieve pain and improve function, but recent studies indicate that up to 20% of patients experience chronic post-surgical pain (CPSP) after total knee replacement; this equates t...
0
Vague Posterior Knee Discomfort in a Soccer Player: A Clinical Vignette
Pediatric Supracondylar Humerus Fracture 2020 Review
A 24-yr-old male soccer player presented with a 7-yr history of left posterior knee "looseness." Evaluation 7 yrs ago, at the time of initial injury, revealed atraumatic anterior and posterior cruciate ligament sprains. On representation, the patient described the pain as a constant, dull ache, 3/10, but his biggest co...
0
Colour Doppler ultrasonography to detect pannus in knee joint synovitis
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: To determine if colour Doppler ultrasonography can characterise the nature of intraarticular echogenic structures and synovial villi more precisely than conventional ultrasonography. METHODS: This is a prospective study on 20 patients--10 with rheumatoid arthritis and 10 with osteoarthritis. Colour Doppler u...
0
Transtemporal midface lifting to blend the lower eyelid-cheek junction
Upper Eyelid and Brow Surgery
When examining the results of this technique, improvement is noticed in the infraorbital hollowing, midface tissue ptosis, depth of nasolabial folds, and degree of jowling. The greatest overall improvement is the extent of midface ptosis and infraorbital hollowing at the lower eyelid-cheek junction followed by improvem...
0
Conversion from temporary external fixation to definitive fixation: shaft fractures
DoD SSI (Surgical Site Infections)
Temporary external fixation is the most common method of initial stabilization of diaphyseal fractures in forward surgical hospitals. Once the patient arrives at a stable environment, usually the United States, the fracture is managed with intramedullary nailing, small-pin external fixation, or a modified external fixa...
0
Tendinopathy
PRPs for Lateral Epicondylitis/Elbow Tendinopathies
Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by pain, decline in function and reduced exercise tolerance. The most common overuse tendinopathies involve the rotator cuff tendon, medial and lateral elbow epicondyles, patellar tendon, gluteal tendons and the Achilles tendon. The pr...
1
Aseptic versus Sterile Acellular Dermal Matrices in Breast Reconstruction: An Updated Review
Acellular Dermal Matrix
BACKGROUND: As the use of acellular dermal matrices in breast reconstruction has become more commonplace and efforts are made to improve on postoperative outcomes, the method of acellular dermal matrix (ADM) processing (aseptic versus sterile) has become a subject of interest. This article provides an updated overview ...
0
Depression following hip fracture is associated with increased physical frailty in older adults: the role of the cortisol: dehydroepiandrosterone sulphate ratio
Hip Fx in the Elderly 2019
BACKGROUND: Hip fracture in older adults is associated with depression and frailty. This study examined the synergistic effects of depression and hip fracture on physical frailty, and the mediating role of the cortisol:dehydroepiandrosterone sulphate (DHEAS) ratio. METHODS: This was an observational longitudinal study ...
0
Expert consensus from the Italian Society for Colposcopy and Cervico-Vaginal Pathology (SICPCV) for colposcopy and outpatient surgery of the lower genital tract during the COVID-19 pandemic
Coronavirus Disease 2019 (COVID-19)
In the context of the COVID-19 pandemic, patients need to be evaluated within 2-4 weeks in the following cases: cytology result of "squamous cell carcinoma," "atypical glandular cells, favor neoplastic," "endocervical adenocarcinoma in situ," or "adenocarcinoma"; histopathological diagnosis of suspected invasion from c...
0
Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions
OAK 3 - Non-arthroplasty tx of OAK
Cartilage degeneration in the course of osteoarthritis (OA) is associated with an alteration in chondrocyte metabolism. In order to identify molecules representing putative key regulators for diagnosis and therapeutic intervention, we analyzed gene expression and microRNA (miR) levels in OA and normal knee cartilage us...
0
Bisphosphonate guidelines for treatment and prevention of myeloma bone disease
MSTS 2018 - Femur Mets and MM
Multiple myeloma (MM) is a haematological malignancy characterised by the clonal proliferation of plasma cells in the bone marrow. More than 80% of patients with MM display evidence of myeloma bone disease (MBD), characterised by the formation of osteolytic lesions throughout the axial and appendicular skeleton. MBD si...
0
Novel therapies in the treatment of multiple myeloma
MSTS 2018 - Femur Mets and MM
Multiple myeloma (MM) is a clonal B-cell malignancy characterized by aberrant expansion of plasma cells within bone marrow and extramedullary sites. In 2009, 20,580 new cases of MM and 10,580 deaths from the disease occurred in the United States. Treatment traditionally consists of systemic chemotherapy, with adjunctiv...
0
Combined internal and external fixation of distal radius fractures
Distal Radius Fractures
Combined internal and external fixation of distal radius fractures is used most commonly to treat injuries with joint surface or metaphyseal comminution. External fixation aids reduction intraoperatively and facilitates arthroscopic, per-cutaneous, or open manipulation of the fracture. Internal fixation maintains preci...
1
Bacteria isolated from late prosthetic joint infections: dental treatment and chemoprophylaxis
Dental Implant Infection
The recommended administration of prophylactic antibiotics, before and during dental procedures, to persons with total joint prostheses is not without controversy. Hospital and dental charts of 2,693 patients in whom total prosthetic joints were placed at the Veterans Administration Hospitals of Ann Arbor and Allen Par...
0
Quality of life after joint replacement for osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
The increasing prevalence of osteoarthritis and the consequent demand for joint arthroplasty is reflected by the increasing use of health resources and quantification of the effectiveness of clinical and surgical interventions. Health-related quality-of-life instruments are valid in quantifying outcomes after joint art...
0
Assessing recovery and establishing prognosis following total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND PURPOSE: Information about expected rate of change after arthroplasty is critical for making prognostic decisions related to rehabilitation. The goals of this study were: (1) to describe the pattern of change in lower-extremity functional status of patients over a 1-year period after total knee arthropla...
1
The prevalence of articular cartilage changes in the knee joint in patients undergoing arthroscopy for meniscal pathology
AMP (Acute Meniscal Pathology)
PURPOSE: The purposes of this study were to evaluate the prevalence of articular cartilage changes in the knee joint and to analyze predictive factors for these changes in patients undergoing arthroscopy for meniscal pathology. METHODS: Between March 2005 and June 2009, 1,010 patients underwent arthroscopic meniscectom...
0
A Prospective Randomized Controlled Trial Comparing the Efficacy of Fascia Iliaca Compartment Block Versus Local Anesthetic Infiltration After Hip Arthroscopic Surgery
AAHKS (8) Anesthetic Infiltration
Purpose To compare the efficacy of fascia iliaca compartment block (FICB) with local anesthetic infiltration (LAI) of the arthroscopy portals for pain control after hip arthroscopy. Methods A prospective single-blinded randomized controlled trial that involved patients who underwent hip arthroscopy was performed. Parti...
0
Median nerve excursion in response to wrist movement after endoscopic and open carpal tunnel release
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
PURPOSE: To compare the perioperative kinematic effects of endoscopic versus open carpal tunnel release on longitudinal excursion (gliding) and volar displacement (bowstringing) of the median nerve at the wrist region in patients with idiopathic primary carpal tunnel syndrome. METHODS: Sixteen hands of 13 patients were...
0
Optimization of prosthetic foot stiffness to reduce metabolic cost and intact knee loading during below-knee amputee walking: a theoretical study
OAK 3 - Non-arthroplasty tx of OAK
Unilateral below-knee amputees develop abnormal gait characteristics that include bilateral asymmetries and an elevated metabolic cost relative to non-amputees. In addition, long-term prosthesis use has been linked to an increased prevalence of joint pain and osteoarthritis in the intact leg knee. To improve amputee mo...
0
The Role of Distal Third Radius Dual Energy X-ray Absorptiometry (DXA) and Central DXA in Evaluating for Osteopenia and Osteoporosis in Men Receiving Androgen Deprivation Therapy for Prostate Cancer
Management of Hip Fractures in the Elderly
The authors assessed the use of distal third radius dual energy X-ray absorptiometry (DXA) concomitantly with central (hip and lumbar spine) DXA to identify men with osteopenia or osteoporosis receiving androgen deprivation therapy (ADT) for prostate cancer. Initial classification with central DXA demonstrated 60 (17%)...
0
Aripiprazole once-monthly 400 mg: Comparison of pharmacokinetics, tolerability, and safety of deltoid versus gluteal administration
AMP (Acute Meniscal Pathology)
Background: Two open-label, randomized, parallel-arm studies compared pharmacokinetics, safety, and tolerability of aripiprazole once-monthly 400 mg following deltoid vs gluteal injection in patients with schizophrenia. Methods: In the single-dose study, 1 injection of aripiprazole once-monthly 400 mg in the deltoid (n...
0
Prediction of total knee replacement in a 6-month multicentre clinical trila with chondroitin sulfate in knee osteoarthritis: Results from a 4-year observation
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: To identify predictive factors for the incidence of total knee replacement (TKR) during long-term follow-up of knee OA patients who formerly received treatment with chondroitin sulfate (CS) or placebo in a multicentre trial using clinical and quantitative magnetic resonance imaging (qMRI) data. Methods: Knee O...
0
Generalised peripheral nerve dysfunction in acromegaly: a study by conventional and novel neurophysiological techniques
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Twenty four patients with clinical, radiological and biochemical evidence of acromegaly were investigated by a number of independent neurophysiological tests. Two-thirds of the patients showed evidence of generalised peripheral nerve dysfunction. A significant correlation was found between total exchangeable body sodiu...
0
Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC
MSTS 2018 - Femur Mets and MM
BACKGROUND: Ionizing radiation (IR) is one of the major clinical therapies of cancer, although it increases the epithelial-mesenchymal transition (EMT) of non-small cell lung cancer (NSCLC), unexpectedly. The cellular and molecular mechanisms underlying this role are not completely understood. METHODS: We used NSCLC ce...
0
Patients' perceptions of the potential complications of bilateral reduction mammaplasty
Reduction Mammoplasty for Female Breast Hypertrophy
Reduction mammaplasty aims to reduce breast mass whilst improving aesthetic appearance. Post-operative complications may include scar and nipple-related problems, haematoma, infection and glandular necrosis. In our unit, patients undergoing surgical procedures are counselled by a nurse practitioner in addition to initi...
0
Safety and efficacy of intravesical bacillus Calmette-Guerin plus interferon alpha-2b therapy for nonmuscle invasive bladder cancer in patients with prosthetic devices
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
PURPOSE: Patients with bladder cancer who have prosthetic devices, such as a cardiac pacemaker, artificial heart valve or orthopedic hardware, and who undergo intravesical bacillus Calmette-Guerin therapy are theoretically at higher risk for complications, including bacterial seeding of pacemaker wires or orthopedic ha...
0
A PC-based software test for measuring alcohol and drug effects in human subjects
Upper Eyelid and Brow Surgery
A new software-based visual search and divided-attention test of cognitive performance was developed and evaluated in an alcohol dose-response study with 24 human subjects aged 21-62 years. The test used language-free, color, graphic displays to represent the visuospatial demands of driving. Cognitive demands were incr...
1
Cost-effectiveness analysis of coblation technology VS. Mechanical debridement with a shaver in the treatment of knee cartilage lesions-a Spanish payer perspective
AMP (Acute Meniscal Pathology)
Objectives: To conduct a cost-effectiveness analysis between Coblation technology and mechanical debridement with a shaver (MD) in a patient population presenting with chronic pain due to a medial meniscus tear and an International Cartilage Research Society (ICRS) grade III focal chondral lesion. Methods: A decisionan...
0
LIMPING IN CHILDREN
Osteochondritis Dissecans 2020 Review
Limping in children is a common complaint at pediatric, pediatric orthopaedic offices and in emergency rooms. There are several causes for this condition, and identifying them is a challenge. The older the patient, the better the anamnesis and more detailed the physical examination will be, enabling an easier medical a...
0
Knee joint loads and surrounding muscle forces during stair ascent in patients with total knee replacement
OAK 3 - Non-arthroplasty tx of OAK
Total knee replacement (TKR) is commonly used to correct end-stage knee osteoarthritis. Unfortunately, difficulty with stair climbing often persists and prolongs the challenges of TKR patents. Complete understanding of loading at the knee is of great interest in order to aid patient populations, implant manufacturers, ...
0
Relationship between medial meniscal extrusion and cartilage loss in specific femorotibial subregions: Data from the osteoarthritis initiative
OAK 3 - Non-arthroplasty tx of OAK
Objective Medial meniscal extrusion is known to be related to structural progression of knee osteoarthritis. However, it is unclear whether medial meniscal extrusion is more strongly associated with cartilage loss in certain medial femorotibial subregions than in others. Methods Segmentation of the medial tibial and fe...
0
A new consideration in athletic injuries. The classical ballet dancer
AMP (Acute Meniscal Pathology)
The professional ballet dancer presents all of the problems of any vigorous athlete. The problems include osteochondral fractures, sprains, chronic ligamentous instability of the knee, meniscal tears, impingement syndrome, degenerative arthritis of multiple joints and low back pain. Attention to minor problems with sou...
0
Alternatives for the treatment of local advanced disease: electrochemotherapy, limb perfusion, limb infusion, intralesional IL2. What is the role?
Reconstruction After Skin Cancer
Nowadays, melanoma is one of the most common fatal malignancy of young adults. Incidence is increasing, but mortality rates from melanoma have remained stable. In-transit metastases from extremity or trunk melanoma are subcutaneous or cutaneous deposits of melanoma distant from the primary site, but not reaching the dr...
0
Association between the severity of femoral condylar cartilage erosion related to knee osteoarthritis by ultrasonographic evaluation and the clinical symptoms and functions
OAK 3 - Non-arthroplasty tx of OAK
Abstract Objective To determine the association between the severity of femoral condylar cartilage erosion resulting from knee osteoarthritis (OA) by an ultrasonographic grading system and the clinical symptoms and functions. Design Cross-sectional study. Setting A tertiary center. Participants Participants (N=101) wit...
0
Systematic review of rehabilitation versus operative stabilization for the treatment of first-time anterior shoulder dislocations
SR for PM on OA of All Extremities
CONTEXT: Primary anterior shoulder dislocation is a frequent injury in young active patients. Traditionally, conservative nonoperative primary treatment has been advocated for a majority of first-time dislocators, whereas operative stabilization has been reserved for recurrent dislocators or those involved in strenuous...
0
Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty
AAHKS (9/10) Regional Nerve Blocks
The study is a prospective, randomized controlled clinical trial comparing two methods of postoperative analgesia following primary TKA. Eligible primary TKA patients must be ASA I � III and require less than 20 mg oxycodone daily (or its equivalent). Exclusion criteria are: allergy to anesthetics, contraindication t...
0
A comparison of stability and clinical outcomes in single-radius versus multi-radius femoral design for total knee arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
We compared the intraoperative varus-valgus stability from 0° to 90° of flexion and postoperative clinical outcomes in patients receiving TKA via either a single-radius femoral design (50 TKA, SR group) or multi-radius femoral design (50 TKA, MR group). We measured stabilities at 0°, 30°, 60° and 90° of flexion u...
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Myeloma bone disease
MSTS 2018 - Femur Mets and MM
Bone destruction is a hallmark of myeloma, with 70% to 80% of patients manifesting bone involvement. Destruction is mediated through normal osteoclasts (OCLs), which respond to local osteoclast-activating factors (OAFs) produced by myeloma cells or by other cells in the local microenvironment. OAFs implicated in myelom...
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Failed joint unloading implant system in the treatment of medial knee osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
In the setting of end-stage osteoarthritis of the knee, total knee arthroplasty is the gold-standard treatment. Recently, a minimally invasive, joint preserving treatment option in the treatment of medial osteoarthritis of the knee has been developed. It is called the KineSpring((R)) (Moximed((R)) International GmbH, Z...
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Antimicrobial photodynamic therapy: photodynamic antimicrobial effects of malachite green on Staphylococcus, enterobacteriaceae, and Candida
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
OBJECTIVE: This study investigated in vitro the photodynamic antimicrobial effects of the photosensitizer malachite green on clinical strains of Staphylococcus, Enterobacteriaceae, and Candida. MATERIALS AND METHODS: Thirty-six microbial strains isolated from the oral cavity of patients undergoing prolonged antibiotic ...
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Reconstruction of massive midfoot bone and soft tissue loss as a result of blast injury
DoD SSI (Surgical Site Infections)
Lower extremity blast injuries represent a unique challenge to surgeons and often involve complex, limb-threatening wounds with extensive soft tissue and bone loss. Surgical treatment of these injuries can be difficult because of limited autogenous resources for reconstruction of the defect. In this article, we describ...
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Comparison of patellar resurfacing and nonresurfacing in total knee arthroplasty: A prospective randomized study
Surgical Management of Osteoarthritis of the Knee CPG
This study was conducted to evaluate the advantages and disadvantages of patellar resurfacing in total knee arthroplasty. One hundred consecutive total knee arthroplasties were performed by the authors. The knees were randomized into two groups of 50 knees, pre-operatively. Five patients (knees) dropped out during foll...
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Blood transfusion and cytokines' changes in total knee replacement
OAK 3 - Non-arthroplasty tx of OAK
INTRODUCTION: The aim of this prospective comparative study was to evaluate the serum levels of different cytokines and the frequency of adverse reactions and wound infections in patients who underwent total knee replacement (TKR) and were not transfused or received either allogeneic blood transfusion or postoperative ...
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The effect of femoral notching during total knee arthroplasty on the prevalence of postoperative femoral fractures and on clinical outcome
Surgical Management of Osteoarthritis of the Knee CPG
Background: The treatment of a supracondylar femoral fracture following total knee arthroplasty is complicated by the presence of the prosthetic components. Anterior femoral notching during arthroplasty has been implicated as a contributing risk factor for femoral fracture. We retrospectively reviewed the effect of ant...
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Circular external fixator-assisted ankle arthrodesis following failed total ankle arthroplasty
PJI DX Updated Search
BACKGROUND: Failed total ankle arthroplasty (TAA) often results in significant bone loss and requires salvage arthrodesis. This study quantified the bone loss following failed TAA and reports the outcome of seven arthrodesis reconstructions using the Ilizarov method. METHODS: A retrospective review of ankle fusions was...
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A Review of State Guidelines for Elective Orthopaedic Procedures During the COVID-19 Outbreak
Coronavirus Disease 2019 (COVID-19)
BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic has resulted in widespread cancellation of elective orthopaedic procedures. The guidance coming from multiple sources frequently has been difficult to assimilate as well as dynamic, with constantly changing standards. We seek to communicate the current guidelines published...
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Spinal narcotics for postoperative analgesia in total joint arthroplasty. A prospective study
Management of Hip Fractures in the Elderly
Sixty patients who were scheduled to have an elective total hip or knee arthroplasty were randomly assigned to one of three groups of twenty patients each before operation with spinal anesthesia. A double-blind technique was used throughout the study. The patients in Group I (control group) received hyperbaric 1 per ce...
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Phase II study of zoledronic acid combined with docetaxel for non-small-cell lung cancer: West Japan Oncology Group
MSTS 2018 - Femur Mets and MM
The aim of this open-label, multicenter, randomized phase II trial was to evaluate the efficacy and safety of zoledronic acid in combination with docetaxel in previously treated patients with non-small-cell lung cancer (NSCLC) and bone metastases. In this study, patients randomly received docetaxel (60 mg/m2) with (gro...
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Device-associated infections: A macroproblem that starts with microadherence
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Medical devices are responsible for a large portion of nosocomial infections, particularly in critically ill patients. Device-associated infections can cause major medical and economic sequelae. Bacterial colonization of the indwelling device can be a prelude to both infection and malfunction of the device. The pathoge...
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Kirschner wire pin tract infection rates: a randomized controlled trial between percutaneous and buried wires
Distal Radius Fractures
This prospective, randomized trial compares the infection rates of Kirschner wires left percutaneously and those buried deep to the skin in a group of patients with isolated distal radial fractures. Percutaneous wires had a significantly greater infection rate than wires which were buried deep to the skin.
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[The manipulation and effects of continuous femoral nerve block after performing a combined spinal and epidural anesthesia]
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: To evaluate the manipulation and effects of continuous femoral nerve block after performing a combined spinal and epidural anesthesia. METHODS: 60 patients, ASAI-II, scheduled for elective total knee arthroplasty were randomized to PRE group or POST group (n = 30 for the each). CFNB was implemented before CS...
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Distribution of aromatase P450 transcripts and adipose fibroblasts in the human breast
Reduction Mammoplasty for Female Breast Hypertrophy
The fibroblast component of adipose tissue is the primary extraglandular site of aromatase P450 (P450arom) expression, which is responsible for the conversion of C19 steroids to estrogens. Previously, we have shown positive correlations between the level of P450arom transcripts and the ratio of fibroblasts to mature ad...
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Lateral patellofemoral ligament reconstruction using a free gracilis autograft
Surgical Management of Osteoarthritis of the Knee CPG
Medial patellofemoral instability is a rare, disabling condition that is often associated with the wrong indication for lateral retinacular release or overcorrection with medializing tibial tubercle osteotomy. It is an even less common complication after total knee arthroplasty (TKA). The lateral patellofemoral ligamen...
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The partial AlloDerm sling: reducing allograft costs associated with breast reconstruction
Acellular Dermal Matrix
BACKGROUND: Many surgeons now incorporate Acellular Dermal Matrix (ADM) into expander-based breast reconstruction. ADM is safe, provides full expander coverage, eliminates the need for additional muscular dissection and has improved aesthetic outcomes. However, its use increases surgical costs. Whether this cost is off...
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Minimally invasive periprosthetic plate osteosynthesis using the locking attachment plate
PJI DX Updated Search
OBJECTIVE: Stable fixation of periprosthetic or periimplant fractures with an angular stable plate and early weight bearing as tolerated. INDICATIONS: Periprosthetic femur fractures around the hip, Vancouver type B1 or C. Periprosthetic femur and tibia fractures around the knee. Periprosthetic fractures of the humerus....
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The role of sarcopenia with and without fracture
Hip Fx in the Elderly 2019
INTRODUCTION: Bone and muscle tissues are in a close relationship. They are linked from a biological and functional point of view and both are related to an increased fracture risk in the elderly. The aging process is involved in the loss of functionality of both bones and muscles. In particular, aging-induced decline ...
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Postoperative analgesia in patients older than 75 years undergoing intervention for per-trochanteric hip fracture: a single centre retrospective cohort study
Hip Fx in the Elderly 2019
The aim of this study was to compare the efficacy of four analgesia techniques on postoperative pain after per-trochanteric femur fracture. A retrospective cohort study was conducted on 131 consecutive patients older than 75 years enrolled in an 18-month period and who underwent per-trochanteric fracture repair under s...
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Management of soft-tissue injuries in distal radius fractures
DOD - Acute Comp Syndrome CPG
Distal radius fractures account for approximately 15% of all fractures in adults, and are the most common fractures seen in the emergency department. Soft-tissue injuries associated with distal radius fractures may influence strategies for the acute management of the fracture, but also may be a source of persisting pai...