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1 | Medical lessons learnt from the US and Canadian experience of treating combat casualties from Afghanistan and Iraq | DoD LSA (Limb Salvage vs Amputation) | The Winston Churchill Memorial Trust, established in 1965, funds Travelling Fellowships and both authors visited hospitals in Germany, Canada and the USA regarded as centres of excellence with expertise in the early care, reconstruction and rehabilitation of the combat casualties of our NATO Allies, as recipients of th... |
0 | Correction of Tibial Valgus Deformity | AMP (Acute Meniscal Pathology) | Valgus tibial malalignment may be the result of bony deformity, previous lateral meniscectomy, or lateral plateau fractures. The correction of such a problem is usually addressed through a tibial osteotomy, which affects the alignment both in flexion and extension. Two surgical options are available: medial closing wed... |
1 | Why paediatric knee surgery is not just knee surgery on small knees | AMP (Acute Meniscal Pathology) | Paediatric knee surgery is a developing subspecialty in the UK. The rise in early participation of children in organized competitive sports has led to an increase in knee injury presentations, and brings unique challenges. Children's knee surgery encompasses varied and complex pathologies, and combines expertise in sof... |
0 | Treatment of non-union of the humerus using the Orthofix external fixator | Glenohumeral Joint OA | An Orthofix monolateral axial external fixator was used to treat 31 patients with non-union of the humeral shaft, 30 of whom had been previously treated surgically. In seven cases the non-union was hypertrophic and one of these cases had been treated by simple fixation anol compression, the others by fixation, bone gra... |
0 | Accident or osteoporosis? Survey of community follow-up after low-trauma fracture | Pediatric Supracondylar Humerus Fracture 2020 Review | Objective: To describe the postfracture osteoporosis management of at-risk patients presenting with low-trauma fracture in a suburban community hospital setting. Design: Telephone survey. Setting: Hospital emergency department serving a retirement community in White Rock and South Surrey, BC. Participants Men and women... |
1 | The effect of electromagnetic navigation in total knee arthroplasty on knee kinematics during functional activities using flexible electrogoniometry | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Navigated total knee arthroplasty has been shown to increase accuracy in post operative implant alignment. By contrast navigated total knee arthroplasty has not shown significant functional improvements to date, when compared with conventional surgery using subjective clinical questionnaire scores. The aim ... |
1 | Interventions for treating bisphosphonate-related osteonecrosis of the jaw (BRONJ) | MSTS 2018 - Femur Mets and MM | Background: Bisphosphonate drugs can be used to prevent and treat osteoporosis and to reduce symptoms and complications of metastatic bone disease; however, they are associated with a rare but serious adverse event: osteonecrosis of the maxillary and mandibular bones. This condition is called bisphosphonate-related ost... |
0 | Micrornas are related to progression of osteoarthritis (OA) in the DMM ( destablization of medial meniscus) mouse model | Surgical Management of Osteoarthritis of the Knee CPG | MicroRNAs (miRNAs)have emerged as key regulators of normal cellular processes and metabolic pathways in the skeleton and are associated with disease. Studies of OA tissue have identified gain and loss of miRNAs that reflect loss of the articular surface, tissue degradation, pain and inflammation. Here we addressed the ... |
0 | Amelioration of osteoporosis and hypovitaminosis D by sunlight exposure in stroke patients | Management of Hip Fractures in the Elderly | BACKGROUND: The authors' previous investigations have disclosed low serum 25-hydroxyvitamin D (25-OHD) concentrations in 45 patients during long-term hospitalization following stroke (mean 5.9 ng/mL). This 25-OHD deficiency resulted from sunlight deprivation. OBJECTIVE: To evaluate the efficacy of sunlight exposure in ... |
1 | A comparative study of the therapeutic effect between long and short intramedullary nails in the treatment of intertrochanteric femur fractures in the elderly | Hip Fx in the Elderly 2019 | PURPOSE: To compare the clinical effects of long vs. short intramedullary nails in the treatment of intertrochanteric fractures in old patients more than 65 years old.
METHODS: A retrospective analysis of 178 cases of intertrochanteric fractures of the femur (AO type A1 and A2) in the elderly was conducted from January... |
0 | Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis | AMP (Acute Meniscal Pathology) | OBJECTIVE: To determine the concentrations of human stromelysin-1, collagenase, tissue inhibitor of metalloproteinases (TIMP), and proteoglycan fragments in knee synovial fluid in patients with injury to the meniscus or anterior cruciate ligament, posttraumatic osteoarthritis, primary osteoarthritis, or pyrophosphate a... |
0 | Laparoscopic versus open pyeloplasty for ureteropelvic junction obstruction in children: A systematic review and meta-analysis | Panniculectomy & Abdominoplasty CPG | Purpose: To comprehensively review the available evidences in the literature on the use of laparoscopic pyeloplasty (LP) vs open pyeloplasty (OP) for the repair of ureteropelvic junction (UPJ) obstruction in children. Materials and Methods: Published studies until the end of October 2010 were searched from Medline, Emb... |
0 | Predicting Pathologic Bone Lesions Using Scout Computed Tomography (CT) Imaging | MSTS 2022 - Metastatic Disease of the Humerus | The purpose of this study is to evaluate the benefit of reviewing scout CT images, obtained for routine oncologic surveillance, for the early identification of pathologic bony lesions. A retrospective review was conducted on patients who previously underwent surgical treatment by two orthopedic oncology surgeons at a t... |
1 | Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trial | MSTS 2018 - Femur Mets and MM | BACKGROUND: The authors previously reported the efficacy of a dose of 4 mg of zoledronic acid in reducing skeletal complications in patients with bone metastases secondary to lung carcinoma and other solid tumors (except carcinomas of the breast and prostate). In the current study, they update these results and report ... |
0 | History and evolution of the Sauvé-Kapandji procedure | Distal Radius Fractures | Arthrodesis of the distal radioulnar joint combined with the creation of a pseudarthrosis of the distal ulna is frequently referred to as the sauvé-kapandji procedure. This eponym is based on the 1936 report by Sauv and Kapandji, which is believed to be the first report of this innovative technique. There has been som... |
0 | Patient Satisfaction and Nipple-Areola Sensitivity After Bilateral Prophylactic Mastectomy and Immediate Implant Breast Reconstruction in a High Breast Cancer Risk Population: Nipple-Sparing Mastectomy Versus Skin-Sparing Mastectomy | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Prophylactic skin-sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM) both are associated with major risk reduction in women with high breast cancer risk. Skin-sparing mastectomy followed by nipple-areola complex (NAC) reconstruction is standard of care, but NSM is increasingly being performed. Pre... |
0 | Significance of C-reactive protein in osteoarthritis and total knee arthroplasty outcomes | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: The relationship between systemic inflammatory processes to total knee arthroplasty (TKA) outcomes remains unclear. This study investigates the relationship between serum high-sensitivity C-reactive protein (hs-CRP) and functional outcomes post-TKA. METHODS: A total of 31 patients with osteoarthritis (OA) w... |
0 | The use of the cemented Exeter Universal femoral stem in a District General Hospital: a minimum ten-year follow-up | Dental Implant Infection | We describe the survivorship of the Exeter femoral component in a District General Hospital. Between 1994 and 1996, 230 Exeter Universal cemented femoral components were implanted in 215 patients who were reviewed at a mean of 11.2 years (10 to 13). We used one acetabular implant, the Elite Ogee component, in 218 of th... |
0 | Interrater and Intrarater Reliability of Musculoskeletal Ultrasonographic Findings for the Common Extensor Tendon of the Elbow | PRPs for Lateral Epicondylitis/Elbow Tendinopathies | Objectives: This retrospective case study evaluated the interrater and intrarater reliability of seven common extensor tendon pathologic features on musculoskeletal ultrasonography (MSK-US). Materials and Methods: A cohort of 50 patients were imaged due to presenting with atraumatic nonradicular lateral elbow pain. Thr... |
1 | Is the umbilicus truly midline? Clinical and medicolegal implications | Panniculectomy & Abdominoplasty CPG | A common misconception is that the umbilicus is a midline structure. To date, an anatomical survey examining whether the umbilicus is located at the midline has not been reported. This study measured the position of the umbilicus among 136 subjects, in two separate experiments. The results demonstrated that the umbilic... |
0 | Pharmaceutical approval update | OAK Recommendation 9 Articles | Droxidopa (Northera) for neurogenic orthostatic hypotension, elosulfase alfa (Vimizim) for Morquio A syndrome, and sodium hyaluronate in phosphate-buffered saline (Monovisc) to address knee osteoarthritis |
0 | Reverse shoulder arthroplasty for proximal humerus fracture: a more complex episode of care than for cuff tear arthropathy | DoD SSI (Surgical Site Infections) | Background: The purpose of this investigation is to identify the in-hospital and 30-day postoperative complications for reverse total shoulder arthroplasty (RTSA) performed because of proximal humerus fracture (PHFx) vs. cuff tear arthropathy (CTA), and determine whether acute fracture is associated with differences in... |
0 | A Randomized, Double-Blind, Parallel Group, Vehicle-Controlled Study to Evaluate the Safety and Efficacy of OMS103HP-S Administered in Joint Irrigation Solution to Subjects Undergoing Arthroscopic Meniscectomy | OAK 3 - Non-arthroplasty tx of OAK | INTERVENTION: Product Name: OMS103HPâ?S Product Code: OMS103HPâ?S Pharmaceutical Form: Irrigation solution INN or Proposed INN: KETOPROFEN CAS Number: 22071â?15â?4 Concentration unit: mg/ml milligram(s)/millilitre Concentration type: equal Concentration number: 0.687 â? INN or Proposed INN: AMITRIPTYLINE HYDROCHLO... |
0 | Bone mineral density and osteoporosis risk in older patients with schizophrenia | Management of Hip Fractures in the Elderly | OBJECTIVE: People with schizophrenia are at a higher risk for osteoporosis. The authors investigated the prevalence of low bone density and its risk factors in older Korean patients with schizophrenia. METHOD: In cross-sectional study, 327 inpatients with schizophrenia were screened. Among them, 229 patients older than... |
0 | An eclectic history of peripheral nerve surgery | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | It is hard to decide where history stops and contemporary development of peripheral nerve surgery begins. This article provides an eclectic view of the history of peripheral nerve surgery. In trying to keep the story moving, the publications of many authors have been omitted. For this, we are sorry. We have also stoppe... |
0 | Exacerbation of rheumatoid arthritis after removal of adrenal adenoma in Cushing's syndrome | Surgical Management of Osteoarthritis of the Knee CPG | A 46-year-old woman with rheumatoid arthritis had been on non-steroidal antiinflammatory agents for eighteen years until she developed cushingoid features and hypertension resistant to antihypertensive drugs. She had high plasma cortisol and 24 h urinary 17-hydroxycorticosteroids (17HCS) which were not suppressed by 8 ... |
0 | Arthroscopic debridement of the degenerative knee - Is there still a role? | OAK 3 - Non-arthroplasty tx of OAK | Objectives: The role of arthroscopic debridement in the painful degenerative knee is controversial. Studies have shown that arthroscopic surgery for knee osteoarthritis provides no additional benefit to optimized physical and medical therapy. There are however, limited studies on the management of the subgroup of signi... |
0 | Intra-abdominal hypertension after life-threatening penetrating abdominal trauma: prophylaxis, incidence, and clinical relevance to gastric mucosal pH and abdominal compartment syndrome | DOD - Acute Comp Syndrome CPG | OBJECTIVE: To define the incidence, prophylaxis, and treatment of intra-abdominal hypertension (IAH) and its relevance to gut mucosal pH (pHi), multiorgan dysfunction syndrome, and the abdominal compartment syndrome (ACS).
METHODS: Seventy patients in the SICU at a Level I trauma center (1992-1996) with life threatenin... |
1 | Prevalence of pain in patients 1 year after major trauma | DoD PRF (Psychosocial RF) | OBJECTIVES: To describe the prevalence of pain in a large cohort of trauma patients 1 year after injury and to examine personal, injury, and treatment factors that predict the presence of chronic pain in these patients. SETTING: Sixty-nine hospitals in 14 states in the United States. PATIENTS: There were 3047 patients ... |
0 | Multidisciplinary team approach in the management of popliteal artery injury | DoD LSA (Limb Salvage vs Amputation) | Popliteal artery injuries (PAIs) remain a challenging entity and carry the greatest risk of limb loss among traumatic lower extremity vascular injuries. Operative management of traumatic popliteal vascular injuries continues to evolve. Improved diagnostic imaging and the introduction of endovascular techniques offered ... |
0 | The clinical features and outcome of crush patients with acute kidney injury after the Wenchuan earthquake: Differences between elderly and younger adults | DoD SSI (Surgical Site Infections) | Background: On May 12, 2008, a devastating earthquake hit Wenchuan county of China's Sichuan province. Acute kidney injury (AKI) is one of the most lethal but reversible complications of crush syndrome after an earthquake. However, little is known about the epidemiological features of elderly crush patients with AKI. T... |
0 | Recovery of elbow motion following pediatric lateral condylar fractures of the humerus | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | BACKGROUND: Temporary elbow stiffness is often seen after a lateral condylar fracture of the distal end of the humerus in children. There are scant scientific data available to assess the expected time frame for return of elbow motion after these injuries. The purpose of this study is to provide a prospective, longitud... |
0 | Knotless Suture Anchor Fixation of a Traumatic Osteochondral Lesion of the Lateral Femoral Condyle | Osteochondritis Dissecans 2020 Review | Osteochondral injuries commonly occur after lateral patellar instability events. Recognition and early intervention of displaced fragments is key to maintaining the viability of the fragment and congruency of the articular surface. Multiple fixation techniques exist for achieving stable fixation of displaced osteochond... |
0 | Soft tissue knee injuries | AMP (Acute Meniscal Pathology) | Soft tissue knee injuries represent a large spectrum of pathology from the minor sprain to devastating knee dislocations. Taking a clear, focussed history and listening to the minutiae that the patient divulges give clues to the mechanism and thus the suspected patterns of injury. A thorough knee examination will allow... |
0 | Poor trabecular microarchitecture at the distal radius in older men with increased concentration of high-sensitivity C-reactive protein--the STRAMBO study | Distal Radius Fractures | Low-grade inflammation, assessed by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with higher fracture risk irrespective of areal bone mineral density (aBMD). We assessed the association of hsCRP with bone microarchitecture (measured by high-resolution pQCT) at the distal radius and tib... |
0 | Femoral nerve block using 0.25% versus 0.5% bupivacaine for analgesia after arthroscopic anterior cruciate ligament reconstruction | Surgical Management of Osteoarthritis of the Knee CPG | Purpose/Objective: Femoral nerve block (FNB) with varying concentrations of bupivacaine is often used for postoperative analgesia after anterior cruciate ligament (ACL) reconstruction. This study investigated whether 0.5% or 0.25% bupivacaine provided better analgesia with less effect on quadriceps strengths. Materials... |
0 | Extraction of a well fixed but fractured ceramic acetabular liner | PJI DX Updated Search | Ceramic fractures have been reported to occur in hip replacements, but the techniques used to extract a well fixed but fractured component are not commonly described. We present a case of ceramic liner fracture and validate a modification of a previously reported extraction technique that allowed us to save the acetabu... |
0 | Complications of Biliary Drainage in Patients with Malignant Biliary Obstruction | MSTS 2022 - Metastatic Disease of the Humerus | Purpose: Biliary tract obstruction in cancer patients is usually associated with a poor prognosis. The obstruction may cause distressing symptoms, such as pruritus. As this situation occurs mostly in advanced cancer, the primary objective of the treatment is in many cases symptom control and not prolonging life. Howeve... |
0 | Fracture Risk After Initiation of Use of Canagliflozin: A Cohort Study | Hip Fx in the Elderly 2019 | Background: Sodium-glucose cotransporter-2 inhibitors promote glycosuria, resulting in possible effects on calcium, phosphate, and vitamin D homeostasis. Canagliflozin is associated with decreased bone mineral density and a potential increased risk for fracture.
Objective: To estimate risk for nonvertebral fracture amo... |
0 | Comparative study of clinical and Electromyographic aspects of Chronic inflammatory demyelinating polyradiculoneuropathy idiopathic between diabetics and non diabetics | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Background The Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) is common in diabetic patients 18.9%. But a few surveys have compared the IPDC between diabetic and non- diabetic. Objective To study the IPDC between diabetic and non- diabetic. Methodology This descriptive survey examined 47 patients incl... |
1 | Augmentation Techniques for Meniscus Repair | AMP (Acute Meniscal Pathology) | Menisci display exquisitely complex structure and play an essential weight-bearing role in the knee joint. A torn meniscus is one of the most common knee injuries which can result in pain and mechanical abnormalities. Tear location is one aspect which determines the endogenous healing response; tears that occur in the ... |
0 | Perioperative and Modifiable Risk Factors for Periprosthetic Joint Infections (PJI) and Recommended Guidelines | Dental Implant Infection | PURPOSE OF REVIEW: Periprosthetic joint infection (PJI) remains a complication that is associated with high morbidity as well as high healthcare expenses. The purpose of this review is to examine patient and perioperative modifiable risk factors that can be altered to help improve rates of PJI., RECENT FINDINGS: Eviden... |
1 | Utility of intraoperative frozen section in the diagnosis of periprosthetic joint infection | PJI DX Updated Search | PURPOSE: Intraoperative frozen section (FS) is an effective diagnostic test for periprosthetic joint infection (PJI). We evaluated the diagnostic characteristics of single- and multiplex-site intraoperative FS, and evaluated the results of single-site FS combined with those of C-reactive protein (CRP) level and erythro... |
0 | Suction lipectomy | Panniculectomy & Abdominoplasty CPG | Suction lipectomy is a very effective and safe method, if performed by an experienced plastic surgeon. The authors demonstrate using a group of 284 patients operated on at the University Clinic of Plastic Surgery in Prague between 1994-1998, indications, the method and complications. |
0 | The golf ball sign: arthroscopic localization of an osteochondritis dissecans lesion of the knee | Osteochondritis Dissecans 2020 Review | We report on the arthroscopic treatment of a 12-year-old boy diagnosed with an osteochondral defect of the medial femoral condyle. He underwent arthroscopic fixation of the defect, and during the surgery, a blunt trocar was used to localize the lesion. The trocar created a transient dimpling effect on the cartilage ove... |
0 | Correlation of Meniscal Tear with Timing of Anterior Cruciate Ligament Reconstruction in Patients without Initially Concurrent Meniscal Tear | AMP (Acute Meniscal Pathology) | The incidence of meniscal tear was reported to increase with the delay of anterior cruciate ligament reconstruction (ACLR). The tear may occur concurrently with the ACL injury or after the ACL injury. Few studies had focused on the patients whose meniscus is intact during ACL injury. We determined the correlation betwe... |
0 | Perioperative hyperglycemia and postoperative infection after lower limb arthroplasty | PJI DX Updated Search | BACKGROUND: One of the most serious complications after major orthopedic surgery is deep wound or periprosthetic joint infection. Various risk factors for infection after hip and knee replacement surgery have been reported, including patients' comorbidities and surgical technique factors. We investigated whether hyperg... |
0 | Clinical outcomes of conversion surgery from an external fixator to an iodine-supported titanium alloy plate | DoD SSI (Surgical Site Infections) | Background: External fixators brought a revolution in orthopaedic surgical treatment after the invention of distraction osteogenesis, which enabled treatment of various difficult diseases. However, they had some drawbacks, such as pin-site infections, psychological pain, and refracture after removal. To overcome these ... |
1 | Hip Fracture Surgery and Survival in Centenarians | Hip Fx in the Elderly 2019 | BACKGROUND: Hip fracture (HF) is increasingly frequent with advancing age. Studies describing the HF incidence rate and survival after surgery in centenarians are scanty. To fill this gap, we performed a large population-based investigation on Lombardy centenarians (Italy).
METHODS: Retrospective observational cohort s... |
1 | Epidemiology of Operative Procedures in an NCAA Division I Football Team Over 10 Seasons | AMP (Acute Meniscal Pathology) | BACKGROUND: Injury rates are high for collegiate football players. Few studies have evaluated the epidemiology of surgical procedures in National Collegiate Athletic Association (NCAA) Division I collegiate football players.
PURPOSE: To determine the most common surgical procedures performed in collegiate football play... |
0 | The nasomaxillary complex, the mandible, and sleep-disordered breathing | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Purpose: This study aims to use clinical scales in a standardized fashion in evaluating the frequency of a high and narrow hard palate and/or small and retroplaced mandible in children with polysomnographically demonstrated sleep-disordered breathing (SDB). Methods: This is a retrospective review of clinical and polyso... |
0 | Outcomes of reduction more than 7 days after injury in supracondylar humeral fractures in children | Pediatric Supracondylar Humerus Fracture 2020 Review | BACKGROUND: Some slightly extended type II fractures initially treated with closed reduction and casting can displace during the first 2 weeks of follow-up. Although closed reduction and percutaneous pinning are desirable for displaced supracondylar humeral fractures treated acutely, there is little or no available inf... |
0 | New and emerging antiresorptive treatments in osteoporosis | MSTS 2018 - Femur Mets and MM | Bisphosphonates have for many years been the mainstay of antiresorptive treatment, acting predominantly by inducing apoptosis of mature osteoclasts. During recent years, an advanced understanding of the genetic and biological mechanism involved in bone resorption has revealed new therapeutic targets for antiresorptive ... |
0 | The Emergency Evaluation and Management of Pediatric Extremity Fractures | Distal Radius Fractures | Approximately one-third of children sustain a fracture before the age of 16 years; however, their unique anatomy and healing properties often result in a good outcome. This article focuses on the diagnosis and management of pediatric extremity injuries. The article describes the anatomic features and healing principles... |
0 | Correlation between macroscopic changes of arthrosis and the posterior cruciate ligament histology in the osteoarthritic knee | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: There is ongoing debate about the role of the posterior cruciate ligament (PCL) in total knee arthroplasty. Advocates of PCL retention cite better soft tissue balance and improved proprioception, whereas opponents report late flexion instability. The results of knee replacement are similar whether the PCL i... |
0 | Aesthetic Nonexcisional Arm Contouring | Panniculectomy & Abdominoplasty CPG | BACKGROUND: Surgical excision remains the gold-standard therapy for arm skin laxity. However, many patients refuse surgical treatment for fear of the prominent long scars associated with brachioplasty. OBJECTIVES: The objective of the study was to compare the aesthetic outcome of 2 energy-assisted liposuction arm-conto... |
0 | Preoperative decolonization effective at reducing staphylococcal colonization in total joint arthroplasty patients | PJI DX Updated Search | Staphylococcus decolonization prior to surgery is used to prevent surgical site infections (SSIs) after total joint arthroplasty (TJA). To determine if current treatment protocols result in successful decolonization of methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA), 106 consecutive pa... |
0 | Anti-inflammatory activity of silymarin in patients with knee osteoarthritis. A comparative study with piroxicam and meloxicam | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: To evaluate the antiâ?inflammatory effect of Silymarin in patients with knee osteoarthritis (OA) in comparison with piroxicam and meloxicam. METHODS: A doubleâ?blind clinical trial was performed at the Department of Rheumatology, Baghdad Teaching Hospital, Baghdad, Iraq during the period from October 2004 ... |
0 | Final results of a phase Iâ??II trial using ex vivo expanded autologous Mesenchymal Stromal Cells for the treatment of osteoarthritis of the knee confirming safety and suggesting cartilage regeneration | OAK 3 - Non-arthroplasty tx of OAK | Background Cellular therapies have shown encouraging results in the treatment of chronic osteoarthritis (OA). Herein, we present the final results of a phase Iâ??II clinical trial assessing the feasibility, safety and efficacy of ex vivo expanded autologous bone marrow Mesenchymal Stromal Cells (MSC, XCEL-M-ALPHA), inf... |
0 | Implanted vascular access device related deep vein thrombosis in oncology patients: A prospective cohort study | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND: Implanted vascular access devices (IVADs) have significantly improved the management of cancer patients. These patients are at an increased risk of venous thromboembolism and IVADs are a known risk factor. We sought to assess the incidence of IVAD-related upper extremity deep vein thrombosis (IVAD-related U... |
0 | Outcomes of Newer Generation Cementless Total Knee Arthroplasty: Beaded Periapatite-Coated vs Highly Porous Titanium-Coated Implants | OAK 3 - Non-arthroplasty tx of OAK | Background Newer generation cementless total knee arthroplasty (TKA) designs are available and have novel implant coatings. We evaluated and compared beaded periapatite (PA)-coated vs highly porous titanium-coated cementless TKAs. Specifically, we compared: (1) survivorship, (2) Knee Society Scores (KSSs) and range of ... |
0 | Emergency department evaluation and treatment of acute hip and thigh pain | Developmental Dysplasia of the Hip 2020 Review | Although the incidence of hip fractures is decreasing, the overall prevalence continues to increase because of an aging population. People older than 65 suffer fractures at a rate of 0.6% per year--2% per year for persons older than 85. One in 5 patients suffering a hip fracture will die within a year. Additionally, th... |
0 | Do we underestimate the predictive value of the ulnar styloid affection in Colles fractures? | Distal Radius Fractures | Various radiographic factors have been suggested as predictively important when dealing with an unstable distal radius fracture. Accordingly, many classification systems have been established in order to give an accurate description of a fracture and to grade the seriousness of the injury. In this paper, we use the cla... |
0 | Adjuvant therapy and prognosis in uterine carcinosarcoma | MSTS 2022 - Metastatic Disease of the Humerus | Purpose: To investigate the prognostic factors and impact of adjuvant treatment on uterine carcinosarcoma (UCS). Methods: A retrospective review of UCS patients treated between 2005 and 2019 was conducted. International Federation of Gynecology and Obstetrics (FIGO) 2009 staging system was used. Multivariate stepwise C... |
0 | Clinical benefits and considerations of bisphosphonate treatment in metastatic bone disease | MSTS 2018 - Femur Mets and MM | Patients with metastatic bone disease are at risk for developing skeletal-related events that can negatively influence quality of life, contributing to loss of autonomy and functional capabilities. Bisphosphonates have become an important component in the treatment of patients with bone metastases as they delay the ons... |
0 | Proteinases and sialyltransferase in human breast tumors | MSTS 2018 - Femur Mets and MM | Proteolytic and sialyltransferase activities were determined in extracts of 65 human primary breast tumors, 6 lymph node metastases, 6 fibroadenomas and 27 normal tissues. Using proteins and synthetic selective substrates, we observed the presence of collagen-peptidases, plasminogen activator, cathepsin-B and cathepsin... |
1 | The acute compartment syndrome following fractures of the lower leg in children | DOD - Acute Comp Syndrome CPG | INTRODUCTION: The acute compartment syndrome (ACS) of the lower leg is a rare but serious complication following either fractures or soft tissue injuries. An acute intervention consisting of fasciotomy is indicated as ACS may cause muscle and nerve damage. The aim of the present study was to evaluate the cause, the inc... |
1 | Responder analysis and correlation of outcome measures: pooled results from two identical studies comparing etoricoxib, celecoxib, and placebo in osteoarthritis | Non-Arthroplasty Treatment of Osteoarthritis of the Knee AUC | OBJECTIVES: To determine the proportion of responders in two identical osteoarthritis (OA) trials using Outcome Measures in Arthritis Clinical Trials-Osteoarthritis Research Society International (OMERACT-OARSI) criteria and to assess the comparability and correlation of individual component measurements. METHODS: Data... |
1 | Intraoperative Infiltration of Liposomal Bupivacaine vs Bupivacaine Hydrochloride for Pain Management in Primary Total Hip Arthroplasty: A Prospective Randomized Trial | AAHKS (8) Anesthetic Infiltration | BACKGROUND: Pain management after total hip arthroplasty is well studied. Nevertheless, there is no consensus regarding the "cocktail" to use in periarticular infiltration (PAI). Liposomal bupivacaine (LB) is a slow release local anesthetic that can be infiltrated during surgery. In this study, we compared LB to bupiva... |
0 | A 10-Year Retrospective Study of 490 Hip Fracture Patients: Reoperations, Direct Medical Costs, and Survival | Hip Fx in the Elderly 2019 | BACKGROUND AND AIMS: Reoperations after operative treatment of hip fracture patients may be associated with higher costs and inferior survival. We examined the acute hospital costs, long-term reoperation rates, and survival of patients with a new hip fracture.
MATERIALS AND METHODS: A total of 490 consecutive new hip f... |
0 | Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect | OAK 3 - Non-arthroplasty tx of OAK | PURPOSE: The aim of this experimental study was to evaluate the effect of intra-articular application of zoledronic acid (ZA) on joint cartilage and synovial tissue following induction of knee osteoarthritis (OA) in a rat model. METHODS: An OA model was created by anterior cruciate ligament transection (ACLT) in the ri... |
1 | Graft selection in anterior cruciate ligament reconstruction--prospective analysis of patellar tendon autografts compared with allografts | Anterior Cruciate Ligament Injuries CPG | A prospective study of 73 arthroscopic anterior cruciate ligament reconstructions using either a patellar tendon autograft or an allograft was made to assess any difference in clinical outcome. Allocation was by availability of an allograft. There were 48 autografts and 25 allografts. Evaluation was by clinical examina... |
1 | Anterior cruciate ligament and meniscal injuries in sports: incidence, time of practice until injury, and limitations caused after trauma | AMP (Acute Meniscal Pathology) | OBJECTIVE: To analyze the incidence of ACL and meniscal injuries in a population of recreational and elite athletes from Brazil and the relation of these injuries with their sports activities.
METHODS: This was a prospective observational study of 240 patients with ACL and/or meniscal injuries submitted to surgical tre... |
0 | Balneotherapy in the treatment of knee osteoarthritis: A controlled study | OAK 3 - Non-arthroplasty tx of OAK | Objectives: This study aims to evaluate the efficacy of combined balneotherapy and physical therapy compared to physical therapy alone in the treatment of patients with knee osteoarthritis. Patients and methods: Forty-six patients (10 males, 36 females; mean age 70.82±7.78 years; range 57 to 85 years) with knee osteoa... |
0 | Patient-oriented outcome measure and risk of knee replacement surgery for the Japanese knee osteoarthritis patients with kellegren-laurence graDe 4 | Surgical Management of Osteoarthritis of the Knee CPG | Purpose: Total knee arthroplasty (TKA) is an effective therapy to control pain and improve function in subjects with severe knee osteoarthritis (OA). However, as the decision whether to have a joint replacement or not is more ambiguous, it is a judgment that has to be maDe by the physician and patient working together,... |
0 | Influence of patient age on the susceptibility patterns of Streptococcus pneumoniae isolates in North America (2000-2001): Report from the SENTRY Antimicrobial Surveillance Program | Patrick’s pharmacoepidemiology project | Risks of developing resistance in Streptococcus pneumoniae can be greatly influenced by antimicrobial use that is often dictated by patterns of prescribing at various patient ages. The results from the SENTRY Antimicrobial Surveillance Program (2000-2001; North America) were examined for differing susceptibility profil... |
0 | Prevalence and risk factors of radiographic vertebral fracture in postmenopausal Vietnamese women | Management of Hip Fractures in the Elderly | Background: Vertebral fracture is associated with an increased risk of atraumatic fracture and mortality. The prevalence of vertebral fractures among postmenopausal Caucasian women has been reported to range between 15% and 35%. Because there is no estimate of the magnitude of the problem in Vietnam, we undertook this ... |
1 | Predictors of posttraumatic stress disorder and symptoms in adults: a meta-analysis | DoD PRF (Psychosocial RF) | A review of 2,647 studies of posttraumatic stress disorder (PTSD) yielded 476 potential candidates for a meta-analysis of predictors of PTSD or of its symptoms. From these, 68 studies met criteria for inclusion in a meta-analysis of 7 predictors: (a) prior trauma, (b) prior psychological adjustment, (c) family history ... |
0 | Revising Recommendations and Outcome Measurements after Complex Open Abdominal Wall Reconstruction | Panniculectomy & Abdominoplasty CPG | Grading systems developed by the Ventral Hernia Working Group (VHWG) for complex open abdominal wall reconstruction rely on limited outcomes: surgical site occurrence (SSO) and hernia recurrence. This does not account for the longitudinal restoration of a functional abdominal wall and the ability to correct complicatio... |
1 | Glenoid component insertion in total shoulder arthroplasty: comparison of three techniques for drying the glenoid before cementation | Glenohumeral Joint OA | This prospective randomized study compared the immediate postoperative periglenoid radiolucencies among 3 glenoid-drying techniques used in total shoulder arthroplasty. Seventy-one consecutive patients with primary osteoarthritis underwent total shoulder arthroplasty by use of 1 prosthetic system with convex-back, keel... |
1 | Comparison of ropivacaine 2 mg ml(-1) and prilocaine 5 mg ml(-1) for i.v. regional anaesthesia in outpatient surgery | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND: Ropivacaine 2 mg ml(-1) (0.2%) provides longer-lasting analgesia after deflation of the tourniquet cuff, with fewer side-effects, than lidocaine 5 mg ml(-1) (0.5%) after i.v. regional anaesthesia (IVRA). Whether ropivacaine 2 mg ml(-1) also exerts this advantage over prilocaine 5 mg ml(-1), the local anaest... |
0 | Older African American women's lived experiences with depression and coping behaviours | DoD PRF (Psychosocial RF) | Little is known about older African American women's lived experiences with depression. What does depression mean to this group? What are they doing about their depression? Unfortunately, these questions are unanswered. This study examined older African American women's lived experiences with depression and coping beha... |
0 | Contribution of each leg to the control of unperturbed bipedal stance in lower limb amputees: new insights using entropy | DoD LSA (Limb Salvage vs Amputation) | The present study was designed to assess the relative contribution of each leg to unperturbed bipedal posture in lower limb amputees. To achieve this goal, eight unilateral traumatic trans-femoral amputees (TFA) were asked to stand as still as possible on a plantar pressure data acquisition system with their eyes close... |
0 | Outcomes of patients with inflammatory breast cancer by hormone receptor- and HER2-defined molecular subtypes: A population-based study from the SEER program | MSTS 2022 - Metastatic Disease of the Humerus | Background: The aim of this study was to evaluate the outcomes of patients with inflammatory breast cancer (IBC), with emphasis on the role of molecular subtypes and radiotherapy. Methods: A retrospective cohort study to investigate overall survival (OS) and breast cancer-specific mortality (BCSM) in patients with IBC ... |
0 | Treatment of knee osteoarthritis with acupuncture and moxibustion: a randomized controlled trial | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: To compare the difference of the efficacy on knee osteoarthritis (KOA) between the combined therapy of acupuncture and moxibustion and western medication, and explore the better therapeutic method for KOA. METHODS: One hundred and sixty patients were divided into a combined therapy group and a western medica... |
0 | Analysis of breast reduction complications derived from the BRAVO study | Reduction Mammoplasty for Female Breast Hypertrophy | Background: Analysis of complication data derived from the Breast Reduction Assessment: Value and Outcomes (BRAVO) study, a 9-month prospective, multicenter trial, is presented. Methods: Data derived from 179 patients were analyzed, including bivariate associations between complications and single predictor variables (... |
0 | Diabetes-accelerated experimental osteoarthritis is prevented by autophagy activation | OAK 3 - Non-arthroplasty tx of OAK | Objective Type 2 Diabetes (T2D) is a risk factor for osteoarthritis (OA). Autophagy, an essential homeostasis mechanism in articular cartilage, is defective in T2D and OA. However, how T2D may influence OA progression is still unknown. We aimed to determine how diabetes affects cartilage integrity and whether pharmacol... |
1 | Endoscopic management of carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | This article describes a subcutaneous endoscopic operative procedure for carpal tunnel syndrome and analyzes its effectiveness using electrophysiological data. Subcutaneous transverse carpal ligament release under universal subcutaneous endoscope (USE) was performed using local anesthesia without pneumotourniquet in 54... |
1 | Aetiology and interrelationship of some common skeletal deformities. (Talipes equinovarus and calcaneovalgus, metatarsus varus, congenital dislocation of the hip, and infantile idiopathic scoliosis) | Developmental Dysplasia of the Hip CPG | The Edinburgh Register of the Newborn 1964-1968 and the Edinburgh Scoliosis Clinic 1964-1971 have been used to establish the population frequency in the city of the idiopathic forms of talipes equinovarus and calcaneovalgus, metatarsus varus, congenital dislocation of the hip, and infantile scoliosis. A survey of 165 p... |
0 | Pasteurella multocida infected total knee arthroplasty: A case report and review of the literature | Surgical Management of Osteoarthritis of the Knee CPG | Pasteurella multocida is a rare cause of prosthetic joint infection. This infection generally follows significant animal contact, usually licks and scratches. We report a case of P multocida infection that was treated with linezolid with salvage of the implant. Linezolid is generally active against Gram-positive organi... |
0 | Computer navigated total knee arthroplasty: aspects of a single unit's experience of 777 cases | Surgical Management of Osteoarthritis of the Knee CPG | The use of computer navigation and conventional techniques in total knee arthroplasty remains controversial. Advocates of computer navigated techniques cite better alignment of components and reduced morbidity associated with avoidance of intramedullary instrumentation as a rationale for their use. In contrast, propone... |
0 | Local tranexamic acid plus diluted epinephrine vs. Intravenous tranexamic acid for reducing bleeding in revision total hip arthroplasty | AAHKS (8) Anesthetic Infiltration | Background: Total joint replacement surgery is associated with large amounts of blood loss and significant rates of transfusions .Postoperative bleeding is one of the most important problems after major orthopedic surgeries including revision Total Hip Arthroplasty (THA). It has been demonstrate that Tranexamic acid is... |
0 | Expression of tumour necrosis factor alpha and its receptors in carcinoma of the breast | Reduction Mammoplasty for Female Breast Hypertrophy | The expression of tumour necrosis factor alpha (TNF-alpha) and its two distinct receptors, TNF-R p55 and TNF-R p75, was assessed by immunocytochemistry in 28 primary breast cancer and three reduction mammoplasty specimens ('normal' breast tissue). Expression of TNF-alpha or TNF-R p75 was not detectable in normal breast... |
0 | Surgical versus conservative interventions for treating ankle fractures in adults | SR for PM on OA of All Extremities | BACKGROUND: The annual incidence of ankle fractures is 122 per 100,000 people. They usually affect young men and older women. The question of whether surgery or conservative treatment should be used for ankle fractures remains controversial. OBJECTIVES: To assess the effects of surgical versus conservative intervention... |
0 | Routine Follow-Up Radiographs for Ankle Fractures Seldom Add Value to Clinical Decision-Making: A Retrospective, Observational Study | DoD PRF (Psychosocial RF) | Currently, the routine use of radiographs for uncomplicated ankle fractures represents good clinical practice. However, radiographs are associated with waiting time, radiation exposure, and costs. Studies have suggested that radiographs seldom alter the treatment strategy if no clinical indication for the imaging study... |
0 | Patient's experiences of RA vs GA for orthopedic surgery | Surgical Management of Osteoarthritis of the Knee CPG | Introduction: The practice of evidence-based medicine stipulates the need for physicians to take into account patient preferences. Empirical research as to how patients can be meaningful engaged in their care is scarce1. It is reported that patients continue to have misgivings and fears about regional anesthesia2 (RA) ... |
1 | Outcome and risk factors after anterior cruciate ligament reconstruction: a follow-up study of 948 patients | Anterior Cruciate Ligament Injuries CPG | PURPOSE: The aim of the study was to assess the outcome and risk factors after anterior cruciate ligament (ACL) reconstruction in a large group of patients. TYPE OF STUDY: Case series. METHODS: Included in this retrospective study were 948 patients (323 female, 625 male) with a symptomatic unilateral ACL rupture, who u... |
0 | The use of galantamine in the treatment of post-traumatic oculomotor and trochlear nerve palsy | Upper Eyelid and Brow Surgery | To assess the suitability of galantamine for the symptomatic treatment of post-traumatic oculomotor (III) and trochlear (IV) nerve palsy. The routine ophthalmic and strabological examination was performed in five patients (4 females and 1 male) at the age of 31 to 57 years (mean 40.7) with the post-traumatic ophthalmic... |
0 | A review of fractures in the proximal femur treated with the Zickel nail | Management of Hip Fractures in the Elderly | The Zickel intramedullary fixation device was used to treat 26 patients with subtrochanteric or impending subtrochanteric fractures. The use of this device has advantages over traditional traction methods as well as nail plate fixation. Twenty-two patients were ambulatory within one month following surgery. Healing of ... |
0 | Loss to follow-up and social background in an inception cohort of patients with severe traumatic brain injury: Results from the Paris-TBI study | DoD PRF (Psychosocial RF) | Objectives: To assess determinants of loss to follow-up (FU) at 2 time points of an inception traumatic brain injury (TBI) cohort. Design and Participants: The Paris-TBI study consecutively included 504 adults with severe TBI on the accident scene (76% male, mean age 42 years, mean Glasgow Coma Scale 5). No exclusion c... |
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