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Extended release local anesthetic agents in a postoperative arthritic pain model
AAHKS (8) Anesthetic Infiltration
Local anesthetics play an important role in postoperative pain management in orthopedic joint procedures. The aim of this study was to determine the effect of an intraoperative extra-articular injection of poly(DL-lactic acid co castor oil 3:7), p(DLLA:CO) 3:7 loaded with 15% bupivacaine, for postoperative analgesia fo...
1
Proï¬쳌le of Patients Diagnosed with Developmental Dysplasia of the Hip
Developmental Dysplasia of the Hip 2020 Review
Objective â??To describe the profile of patients with developmental dysplasia of the hip (DDH) diagnosed by physical and ultrasound examination, with the implementation of a protocol for the treatment and follow-up of DDH. Methods â??A cross-sectional study with DDH patients born between January 2014 and December 2016...
1
The effect of clopidogrel and aspirin on blood loss in hip fracture surgery
Management of Hip Fractures in the Elderly
INTRODUCTION: Anti-platelet drugs are commonly used for primary and secondary prevention of thrombo-embolic events and following invasive coronary interventions. Their effect on surgery-related blood loss and perioperative complications is unclear, and the management of trauma patients treated by anti-platelets is cont...
0
Use of systemic glucocorticoids and the risk of major osteoporotic fractures in patients with sarcoidosis
Hip Fx in the Elderly 2019
Summary: This study revealed the risk of major osteoporotic fracture in patients with sarcoidosis exposed to glucocorticoids. Current use of glucocorticoids was associated with a risk of fracture, with no difference between patients with and without sarcoidosis. Sarcoidosis per se was not associated with an increased f...
0
Fasciotomies of the limbs: how to do it?
DOD - Acute Comp Syndrome CPG
The compartment syndrome has been defined as an elevation of the interstitial pressure in a closed osteofascial compartment resulting in microvascular compromise. The only effective treatment is early decompression of the involved compartment. In acute conditions, this decompression can only be established if skin and ...
0
Posterior root tear of the medial meniscus in multiple knee ligament injuries
AMP (Acute Meniscal Pathology)
The purposes of the present study were to examine the frequency and characteristics of root tears of the medial meniscus associated with ligament injuries of the knee and to evaluate the effectiveness of pull-out repair for restoring meniscus function. We retrospectively analyzed the 9 patients (10 knees) with posterio...
0
Staged multidisciplinary step-up management for necrotizing pancreatitis
DOD - Acute Comp Syndrome CPG
BACKGROUND: Some 15 per cent of all patients with acute pancreatitis develop necrotizing pancreatitis, with potentially significant consequences for both patients and healthcare services. METHODS: This review summarizes the latest insights into the surgical and medical management of necrotizing pancreatitis. General ma...
0
Subject-specific finite element modeling of the tibiofemoral joint based on CT, magnetic resonance imaging and dynamic stereo-radiography data in vivo
AMP (Acute Meniscal Pathology)
In this paper, we present a new methodology for subject-specific finite element modeling of the tibiofemoral joint based on in vivo computed tomography (CT), magnetic resonance imaging (MRI), and dynamic stereo-radiography (DSX) data. We implemented and compared two techniques to incorporate in vivo skeletal kinematics...
0
Thrombolysis for deep venous thrombosis
DOD - Acute Comp Syndrome CPG
The key questions addressed in this summary are whether clot removal should be part of the preferred therapy for patients with acute deep venous thrombosis (DVT), and whether there is evidence that a strategy of thrombus removal offers better outcomes for patients than anticoagulation alone. Evidence is defined as an o...
0
Focal osteoporosis defects play a key role in hip fracture
Hip Fx in the Elderly 2019
BACKGROUND: Hip fractures are mainly caused by accidental falls and trips, which magnify forces in well-defined areas of the proximal femur. Unfortunately, the same areas are at risk of rapid bone loss with ageing, since they are relatively stress-shielded during walking and sitting. Focal osteoporosis in those areas m...
0
Cost-effectiveness analysis of screening for osteoporosis in postmenopausal Japanese women
Management of Hip Fractures in the Elderly
Osteoporosis-related hip fracture is an important cause of mortality and morbidity in older people. In an aging society such as Japan's, prevention and treatment of osteoporosis is of paramount importance in reducing the risk of hip fracture. To determine the efficiency of screening by dual-energy X-ray absorptiometry ...
0
Characterization of initial microfracture defects in human condyles
Surgical Management of Osteoarthritis of the Knee CPG
Microfracture (MFX) is a cartilage repair technique that depends on cell migration from marrow-rich trabecular bone cavities into the cartilage lesion. This study tested the hypothesis that MFX awls with distinct geometry generate different hole shapes and variable bone marrow access in condyles with Grade III to IV le...
0
Extracorporeal Shock Wave Therapy reduces upper limb spasticity and improves motricity in patients with chronic hemiplegia: A case series
Pediatric Supracondylar Humerus Fracture 2020 Review
BACKGROUND: Extracorporeal Shock Wave Therapy (ESWT) has been proposed for treatment of abnormal muscle tone only in the last years. The effects on motor impairment are unknown. OBJECTIVE: To assess the long-term effects of ESWT on muscle tone and motricity in upper limb in patients with chronic hemiplegia. METHODS: Tw...
0
Function versus position of the wrist following distal radial fracture
Distal Radius Fractures
INTERVENTION: Patients with distal radial fractures undergoing reduction and k�wire fixation are randomised to dorsi or palmar flexion in plaster of Paris (POP). Upon removal of POP, grip test is measured using a Jamar Dynamometer. At 8 weeks, grip strength is measured again and the test is repeated at 17 weeks. COND...
0
Humeral amputation following total elbow arthroplasty
MSTS 2022 - Metastatic Disease of the Humerus
PURPOSE: Total elbow arthroplasty (TEA) is associated with a relatively high complication rate, and exceptionally catastrophic complications might lead to amputation. The purpose of this study was to determine the incidence and aetiology of amputation performed at our institution in upper extremity limbs with a prior T...
1
Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications
Acellular Dermal Matrix
BACKGROUND: Little information exists on the incidence of complications after acellular human dermis implantation in two-stage tissue expander breast reconstruction. The purpose of this study was to evaluate the incidence of postoperative adverse events and identify significant predictors of complications in acellular ...
1
Comparison of patient outcomes in periarticular and intraarticular local anaesthetic infiltration techniques in total knee arthroplasty
AAHKS (8) Anesthetic Infiltration
BACKGROUND: The use of local infiltration analgesia in the setting of knee arthroplasty is well established. There are no studies to date which have directly compared differences in infiltration techniques. The purpose of this study is to establish if a difference in patient outcomes exists when the infiltrate is injec...
0
Arthroscopic transtibial single-bundle posterior cruciate ligament reconstruction using patellar tendon graft compared with hamstring tendon graft
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: The purpose of this study was to compare the outcomes of arthroscopic transtibial single-bundle posterior cruciate ligament reconstruction using autologous patellar tendon and hamstring tendon grafts. METHODS: From 1998 to 2007, 59 patients with symptomatic isolated posterior cruciate ligament injury were incl...
0
Incidence of Skeletal-related Events Over Time from Solid Tumour Bone Metastases Reported in Randomised Trials Using Bone-modifying Agents
MSTS 2018 - Femur Mets and MM
Aims: Skeletal-related events (SREs) in patients with bone metastases decrease a patient's quality of life and functional status. Although bone-modifying agents have been found to reduce the time to first on-trial SRE and decrease the total incidence of SREs in randomised clinical trials, standard practice in the manag...
0
Review of Artificial Intelligence Techniques in Imaging Data Acquisition, Segmentation and Diagnosis for COVID-19
Coronavirus Disease 2019 (COVID-19)
The pandemic of coronavirus disease 2019 (COVID-19) is spreading all over the world. Medical imaging such as X-ray and computed tomography (CT) plays an essential role in the global fight against COVID-19, whereas the recently emerging artificial intelligence (AI) technologies further strengthen the power of the imagin...
1
Carpal arch alteration and related clinical status after endoscopic carpal tunnel release
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
One hundred eight endoscopic carpal tunnel releases were performed by a modification of the technique described by Chow. Eighty-seven of the 108 cases were evaluated for quantitative postoperative widening of the transverse carpal arch. The average postoperative widening of the transverse carpal arch was 0.17 cm (7%), ...
0
Corrigendum to â??Blockade of vascular endothelial growth factor receptor-1 (Flt-1), reveals a novel analgesic for osteoarthritis-induced joint painâ?쳌 (Gene Reports (2018) 11 (94â??100), (S2452014418300244) (10.1016/j.genrep.2018.03.008))
OAK 3 - Non-arthroplasty tx of OAK
As the principal investigator and senior author for the above-mentioned publication (Das et al., 2018, GENE REPORTS 11, 94â??100), it has been brought to my attention that a portion of 2.4. Surgical procedure for OA induction in the Materials and Methods section in this publication contains inaccurate description. Henc...
0
Agreement on and predictors of long-term psychosocial development 16 years post-childhood traumatic brain injury
DoD PRF (Psychosocial RF)
Childhood traumatic brain injury (CTBI) is one of the most common causes of childhood mortality and morbidity, with psychosocial impairment being among the most debilitating persisting consequences. Child and adolescent survivors of CTBI have fewer friends and lower self-esteem with a higher risk of developing a psychi...
0
Anterior cruciate ligament reconstruction with autogenous patellar tendon graft in patients with articular cartilage damage
Surgical Management of Osteoarthritis of the Knee CPG
To test if anterior cruciate ligament reconstruction with autogenous patellar tendon can alleviate symptoms and functional limitations and increase activity levels in patients with advanced articular cartilage damage, we looked at 53 patients with arthroscopically documented cartilage damage. In this group, a mean of 7...
0
Correlation between synovial vascular endothelial growth factor, clinical, functional and radiological manifestations in knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Aim of the work: To correlate between synovial vascular endothelial growth factor (VEGF), clinical, functional and radiological findings in knee osteoarthritis (KOA) patients. Patients and methods: Twenty patients with primary KOA were clinically examined and the modified Ritchie articular index (RAI) recorded. The kne...
0
Descriptive analysis and short-term follow-up clinical results of osteochondral lesions of the distal tibia based on data of the German Cartilage Register (Knorpelregister(®) DGOU)
Osteochondritis Dissecans 2020 Review
INTRODUCTION: An increasing number of ankle injuries with osteochondral lesions (OCL) also include lesions of the distal tibia. Therefore, the German Cartilage Society database is used to describe and examine the characteristics of these lesions and, early on, the results of different surgical therapies on the clinical...
1
Early surgical site infection in adult appendicular skeleton trauma surgery: a multicenter prospective series
DoD SSI (Surgical Site Infections)
INTRODUCTION: Surgical site infections (SSI) studies rely on an imprecise and debatable definition. The term "wound healing problems" (WHP), not necessarily septic, is also frequently cited. This study had the objectives of determining the frequency of early SSIs in traumatology, these terms eventual correlation, and t...
0
Treatment of unreduced elbow dislocations with hinged external fixation
Glenohumeral Joint OA
Background: The results of operative treatment of an unreduced elbow dislocation have been regarded with pessimism. Suggested procedures have included tendon-lengthening, tendon transfer, or reconstruction of ligament or bone. Methods: Three women and two men (average age, forty-nine years) with an unreduced dislocatio...
0
Recurrent acute otitis media in infants: analysis of risk factors
Reduction Mammoplasty for Female Breast Hypertrophy
OBJECTIVE: Recurrence acute otitis media (RAOM) may cause a considerable morbidity and a great parental concern. The aim of this study was to analyze the risk factors that are likely to be responsible for RAOM in infants, and their impact on treatment failure. METHODS: A retrospective study on 340 infants with RAOM was...
0
Clinical Management in Early OA
AAHKS (2) Corticosteroids
Knee osteoarthritis affects an important percentage of the population throughout their life. Several factors seem to be related to the development of knee osteoarthritis including genetic predisposition, gender, age, meniscal deficiency, lower limb malalignments, joint instability, cartilage defects, and increasing spo...
0
Interleukin-8 (IL-8) in synovial fluid of rheumatoid and nonrheumatoid joint effusions
AMP (Acute Meniscal Pathology)
IL-8 was measured in knee joint synovial fluid of 60 patients with rheumatoid arthritis, 8 with gout, 6 with osteoarthritis and 4 with meniscus lesions. IL-8 could be demonstrated in most SF samples. The highest levels were observed in rheumatoid joint effusions, yet mean levels were not significantly different between...
0
Does the postoperative dressing regime affect wound healing after hip or knee arthroplasty?
PJI DX Updated Search
OBJECTIVE: The aim of this literature review is to enable practitioners to make informed decisions about how to manage patients with hip or knee arthroplasty wounds. METHOD: A systematic critique of the evidence in relation to how the postoperative dressing regime may affect wound healing after hip or knee arthroplasty...
0
Femoral Shaft Fractures
Hip Fx in the Elderly 2019
Fractures of the femoral shaft are one of the most common injuries treated by orthopedic surgeons. These fractures are often associated with polytrauma and can be life-threatening. They commonly result from high energy mechanisms such as motor vehicle collisions (MVC) with sequelae of limb shortening and deformities if...
0
Postoperative delirium in old patients with femoral neck fracture: a randomized intervention study
Management of Hip Fractures in the Elderly
BACKGROUND AND AIMS: Delirium is a common postoperative complication in elderly patients which has a serious impact on outcome in terms of morbidity and costs. We examined whether a postoperative multi-factorial intervention program can reduce delirium and improve outcome in patients with femoral neck fractures.METHODS...
0
Relationship between Tibial Bone Defect and Extent of Medial Release in Total Knee Arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
PURPOSE: To understand the relationship between tibial bone defect and extent of medial release in total knee arthroplasty. MATERIALS AND METHODS: We evaluated 32 knees in 22 patients with variable degrees of tibial bone defect on medial plateau has undergone total knee arthroplasty. In this study, 31 cases had been di...
0
Ophthalmic and visual profile of guide dog owners in Scotland
Upper Eyelid and Brow Surgery
BACKGROUND/AIMS: Out of an estimated 90,000 visually impaired people in Scotland, 509 make use of a guide dog. Initial research in Northern Ireland suggests that the ophthalmic profile of guide dog owners (GDOs) is highly specific. The aim of this study was to compare the ophthalmic and visual characteristics of Scotti...
0
Total femur replacement: A limb-saving strategy for patients with primary malignant femoral tumors
MSTS 2018 - Femur Mets and MM
Objective: The treatment of primary malignant tumors with skip or extensive bone destruction in the femur is a major challenge. We investigated the clinical effects of total femur replacement (TFR) in patients with primary malignant femoral tumors. Methods: Eleven cases of primary malignant femoral tumors treated with ...
0
Systematic review and meta-analysis of bearing dislocation in lateral meniscal bearing unicompartmental knee replacement: Domed versus flat tibial surface
AMP (Acute Meniscal Pathology)
BACKGROUND: Bearing dislocation is a problem following mobile bearing Oxford lateral Unicompartmental Knee Replacement (UKR). Therefore, the design of the tibial component was changed from a flat tibial surface to a domed tibial surface with a biconcave bearing to increase bearing entrapment. This systematic review com...
0
The prevention and treatment of osteoporosis: A review CME
HipFx Supplemental Cost Analysis
Osteoporosis is a disorder characterized by reduced bone strength, diminished bone density, and altered macrogeometry and microscopic architecture. Adult bone mass is the integral measurement of the bone mass level achieved at the peak minus the rate and duration of subsequent bone loss. There is clearly a genetic pred...
0
Epidural morphine injection after combined spinal and epidural anaesthesia
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND OBJECTIVE: Although combined spinal and epidural anaesthesia is efficient and easy to perform, the technique can be a double-edged sword having the potential risk that an increased flux of drugs across the meninges through the hole made in it may lead to severe adverse effects. The aim was to compare the...
1
Risk factors for revision after shoulder arthroplasty: 1,825 shoulder arthroplasties from the Norwegian Arthroplasty Register
Glenohumeral Joint OA
BACKGROUND AND PURPOSE: Previous studies on shoulder arthroplasty have usually described small patient populations, and few articles have addressed the survival of shoulder implants. We describe the results of shoulder replacement in the Norwegian population (of 4.7 million) during a 12-year period. Trends in the use o...
0
Palliative Management of Nonoperative Femoral Neck Fractures With Continuous Peripheral Indwelling Catheters: Case-Control Series
Hip Fx in the Elderly 2019
Introduction: This case-control study evaluates the success of indwelling pain catheters in nonoperatively treated femoral neck fractures (FNFs) for end-of-life pain management. Methods: Patients older than 65 years with nonoperatively treated FNFs were retrospectively identified at a level 1 trauma center between Marc...
1
Comparative analysis of the surgical treatment results for multiple myeloma bone disease of the spine and the long bone/soft tissue
MSTS 2018 - Femur Mets and MM
The present retrospective study was designed to compare the pain relief, surgery duration, life quality, survival time and relative prognostic factors in multiple myeloma (MM) bone disease patients with different surgical sites. A total of 65 cases were enrolled and divided into two groups. Group A included patients wi...
0
MRI of fractures of the distal radius: comparison with conventional radiographs
Distal Radius Fractures
OBJECTIVE: To compare the evaluation of fractures of the distal radius with MRI and conventional radiographs. To demonstrate the ability of MRI to detect unsuspected soft tissue derangement accompanying this common injury. DESIGN AND PATIENTS: Twenty-one consecutive inpatients admitted following fracture of the distal ...
0
Androgen deprivation therapy: Evidence-based management of side effects
MSTS 2022 - Metastatic Disease of the Humerus
What's known on the subject? and What does the study add? The benefits of androgen deprivation therapy (ADT) are well recognized and a multitude of studies have documented the benefits of ADT in conjunction with other therapies. Given the widespread use of ADT due to its important clinical implications, it is imperativ...
0
Periprosthetic fractures of the femur after hip and knee replacement
Management of Hip Fractures in the Elderly
Objective: To present the clinical and radiological results of treatment of periprosthetic fractures of the femur after hip and knee replacements. Subjects and Methods: Thirty-four patients (8 males and 26 females) with 34 fractures of the femur complicating hip and knee replacements are the subjects of this report. In...
0
Do large pragmatic randomised trials change clinical practice?: Assesing the impact of the Distal Radius Acute Fracture Fixation Trial (DRAFFT)
Distal Radius Fractures
Aims: Our aim, using English Hospital Episode Statistics data before during and after the Distal Radius Acute Fracture Fixation Trial (DRAFFT), was to assess whether the results of the trial affected clinical practice. Patients and Methods: Data were grouped into six month intervals from July 2005 to December 2014. All...
0
Chromosome 1q21 gains confer inferior outcomes in multiple myeloma treated with bortezomib but copy number variation and percentage of plasma cells involved have no additional prognostic value
MSTS 2018 - Femur Mets and MM
Chromosome 1q21 aberrations have not been yet been made part of routine clinical tests and their effect in multiple myeloma is still under investigation. The prognostic value of copy number variation and percentage of plasma cells involved have remained unclear. In the present study, we analyzed the prognostic value of...
0
Treatment of melanoma metastases in a limb by isolated limb perfusion and isolated limb infusion
DOD - Acute Comp Syndrome CPG
In-transit melanoma metastases are often confined to a limb. In this circumstance, treatment by isolated limb perfusion or isolated limb infusion can be a remarkably effective regional treatment option. Copyright © 2011 Wiley-Liss, Inc.
0
Evaluation of Herbert screw fixation for the treatment of displaced scaphoid nonunions
Distal Radius Fractures
Ten cases of unstable scaphoid nonunions treated with Herbert screw fixation were compared to nine cases treated with Herbert screw fixation supplemented with a single Kirschner wire (K-wire) across the fracture site. Corticocancellous bone graft from the distal radius was used in all cases to reconstruct the scaphoid....
1
Treatment of massive rotator-cuff tears with a polyester ligament (Dacron) augmentation: clinical outcome
Optimizing the Management of Full-Thickness Rotator Cuff Tears
We describe the clinical outcome of a technique of surgical augmentation of chronic massive tears of the rotator cuff using a polyester ligament (Dacron) in 21 symptomatic patients (14 men, seven women) with a mean age of 66.5 years (55.0 to 85.0). All patients had MRI and arthroscopic evidence of chronic massive tears...
1
Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial
AAHKS (8) Anesthetic Infiltration
PURPOSE: Combined femoral and sciatic nerve blocks for post-operative pain management following total knee arthroplasty (TKA) improve patient satisfaction, decrease narcotic consumption and improve pain. However, accompanying motoric weakness can cause falls and related complications. We wonder whether peri-capsular in...
0
Arthroplasty patients with diabetes mellitus have higher bone pentosidine levels and greater immunohistochemical rage and mmp-1 than patients without diabetes
Surgical Management of Osteoarthritis of the Knee CPG
We previously identified a higher rate of total joint replacement surgeries (arthroplasty) in patients diagnosed with diabetes mellitus compared to patients without diabetes mellitus in a Veterans Affairs database.1 The purpose of the present study was to identify an effect, if any, of diabetes on joint tissue metaboli...
1
Reverse total shoulder arthroplasty: a review of results according to etiology
Glenohumeral Joint OA
BACKGROUND: Reverse total shoulder arthroplasty provides a surgical alternative to standard total shoulder arthroplasty for the treatment of selected complex shoulder problems. The purpose of the present study was to evaluate the effects of etiology on the results of reverse total shoulder arthroplasty. METHODS: Betwee...
0
Single-stage Abdominoplasty Using Groin Flaps Without Osteotomies: Management of Exstrophy-epispadias Complex
Panniculectomy & Abdominoplasty CPG
BACKGROUND AND OBJECTIVE: The optimal treatment for children born with exstrophy-epispadia complex is still a matter of debate.(1,2)(,)(3) We demonstrate the Single-Stage Abdominoplasty using Groin Flap technique to close the abdominal wall of children with classic bladder exstrophy (CBE) without osteotomy neither radi...
0
Successful prevention of bacterial endophthalmitis in eyes with the Boston keratoprosthesis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
PURPOSE: To determine the influence of topical vancomycin prophylaxis on the incidence of bacterial endophthalmitis in eyes with a Boston Keratoprosthesis (KPro). METHODS: A retrospective chart review was performed for 255 eyes of 231 patients who received a KPro between March 1990 and December 2006. Preoperative diagn...
0
Relationship between undercarboxylated osteocalcin and osteoprotegerin in knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Objective: The purpose of the present study was to evaluate the possible association between the serum levels of undercarboxylated osteocalcin (ucOC) and osteoprotegerin (OPG) in patients with knee osteoarthritis (OA). Methods: Twenty patients (10 men and 10 women) diagnosed to have knee OA, and twenty healthy subjects...
0
High-risk surgically resected pediatric melanoma and adjuvant interferon therapy
Reconstruction After Skin Cancer
Background. Pediatric patients with high-risk surgically resected melanoma are at risk for relapse, yet little is known about these young patients and how they tolerate high-dose interferon therapy. Procedure. We reviewed medical records of patients (â?¤18 years) with high-risk melanoma referred to the University of Mi...
0
Real-life experience with the specific reversal agent idarucizumab for the management of emergency situations in dabigatran-treated patients: a series of 11 cases
Hip Fx in the Elderly 2019
Non-vitamin K antagonist oral anticoagulants (NOACs) have a favorable benefit-risk profile compared with vitamin K antagonists. However, the lack of specific reversal agents has made the management of some patients receiving long-term treatment with NOACs problematic in emergency situations such as major bleeding event...
1
Medial neck femoral fractures: algorithm of treatment and the use of f.g.L. TM memory shape stem
Hip Fx in the Elderly 2019
BACKGROUND AND AIM OF THE WORK: We treat undisplaced or minimally displaced medial neck femoral fractures with screws in both young and elderly patients with good activity of daily living, without severe comorbidity. Total hip replacement is preferred in middle-advanced age, with good level of functional activity. Bipo...
0
Predictors of lower extremity arterial injury after total knee or total hip arthroplasty
DoD LSA (Limb Salvage vs Amputation)
OBJECTIVE: Lower extremity arterial injury is a rare complication following total knee (TKA) or total hip arthroplasty (THA). To date, no multi-institutional study has identified preoperative factors that may portend increased risk for these injuries. We queried a large clinical database for the incidence and predictor...
1
Health-economic evaluation of meniscus tear treatments: a systematic review
AMP (Acute Meniscal Pathology)
PURPOSE: To evaluate the overall evidence of published health-economic evaluation studies on meniscus tear treatment. METHODS: Our systematic review focuses on health-economic evaluation studies of meniscus tear treatment interventions found in PubMed and Embase databases. A qualitative, descriptive approach was used t...
0
Pseudoptosis Correction With the 270 degrees Pedicle Reduction Mammoplasty: An Anatomic and Clinical Study
Reduction Mammoplasty for Female Breast Hypertrophy
Background: Reduction mammoplasty techniques have evolved considerably. Today, aesthetically pleasing results and preservation of nipple sensation and vascularity are emphasized. Achieving the aforementioned goals for the patient with pseudoptosis remains challenging. Objective: We present 270 degrees pedicle reduction...
0
Use of orexigenic medications in geriatric patients
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Background: The loss of appetite, anorexia, is commonly observed in older persons and associated with adverse outcomes. It is becoming increasingly apparent that anorexia is the chief factor in producing weight loss in older adults. Although common and expected in acute illness, anorexia is also frequently associated w...
0
Effects of nerve growth factor (NGF) in rats with basal forebrain lesions
DoD PRF (Psychosocial RF)
Effects of nerve growth factor (NGF) on the basal forebrain (BF) lesion-induced amnesia in rats were investigated. When NGF infusion was begun immediately after the formation of BF lesions, NGF ameliorated amnesia in a water maze task and showed a tendency to increase choline acetyltransferase (CAT) activity in the fro...
0
Complications of Total Hip Arthroplasty: Standardized List, Definitions, and Stratification Developed by The Hip Society
PJI DX Updated Search
BACKGROUND: Reporting of complications after total hip arthroplasty (THA) is not standardized, and it is done inconsistently across various studies on the topic. Advantages of standardizing complications include improved patient safety and outcomes and better reporting in comparative studies. QUESTIONS/PURPOSES: The pu...
0
Induced human gestational hypoprolactinemia: Lack of action on fetal adrenal androgen synthesis
Reduction Mammoplasty for Female Breast Hypertrophy
To investigate the possible role of PRL in the control of fetal adrenal function, blood samples were collected from maternal peripheral and cord blood from six women at delivery, who had received treatment with bromocriptine (3.75-35 mg daily) for the entire gestation. A group of eight untreated parturients served as c...
0
Nightshift work and fracture risk: the Nurses' Health Study
Management of Hip Fractures in the Elderly
SUMMAYR: Nightshift work suppresses melatonin production and has been associated with an increased risk of major diseases including hormonally related tumors. Experimental evidence suggests that light at night acts through endocrine disruption likely mediated by melatonin. To date, no observational study has addressed ...
0
Single photon emission computed tomography in planning unicompartmental knee arthroplasty. A prospective study examining the association between scan findings and intraoperative assessment of osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
The aim of this study was to determine the relationship between preoperative single photon emission computed tomography (SPECT) scan findings and intraoperative assessments of knee osteoarthritis (OA) in patients undergoing tibiofemoral unicompartmental knee arthroplasty (UKA). Fifty knees in 46 patients undergoing UKA...
0
Triclosan can select for an AdeIJK-overexpressing mutant of Acinetobacter baumannii ATCC 17978 that displays reduced susceptibility to multiple antibiotics
Patrick’s pharmacoepidemiology project
In order to determine if triclosan can select for mutants of Acinetobacter baumannii ATCC 17978 that display reduced susceptibilities to antibiotics, we isolated a triclosan-resistant mutant, A. baumannii AB042, by serial passaging of A. baumannii ATCC 17978 in growth medium supplemented with triclosan. The antimicrobi...
1
Sex differences in carpal tunnel syndrome: comparison of surgical and non-surgical populations
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Carpal tunnel syndrome (CTS) patients are known to show gender-related differences in severity. The main aim of this cross-sectional study was to determine whether these differences between women and men may be related to age, education or body mass index (BMI) in two populations, one with idiopathic CTS not treated su...
0
Rehabilitation of the elbow in the throwing athlete
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Rehabilitation following an injury to the elbow joint complex is common in physical therapy practice. The unique anatomical considerations of the elbow joint provide a significant challenge to the therapist in rehabilitating elbow injuries. The purpose of this paper is to describe the rehabilitation process for various...
0
Sesamin inhibits IL-1beta-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway
OAK 3 - Non-arthroplasty tx of OAK
Sesamin, a bioactive component extracted from sesame, has been reported to exert anti-inflammatory and anti-oxidant effects. In this study, we evaluated the anti-inflammatory effects of sesamin on IL-1beta-stimulated human osteoarthritis chondrocytes and investigated the possible mechanism.
0
The American Society for Aesthetic Plastic Surgery (ASAPS) survey: current trends in liposuction
Panniculectomy & Abdominoplasty CPG
BACKGROUND: The emergence of new technologies necessitates a study of current trends in liposuction and other methods for fat removal. OBJECTIVE: The American Society for Aesthetic Plastic Surgery (ASAPS) conducted a survey of its members to gain valuable information from Board-certified plastic surgeons about their ex...
0
Post-operative imaging of soft tissue sarcomas
MSTS AUC - Based on ACR Lit Review
Soft tissue sarcomas are uncommon malignancies that have a high risk of local recurrence despite adequate initial surgery. The aim of follow-up imaging with any malignancy is to detect recurrence promptly so that treatment can be instigated at the earliest possible opportunity. In this review article, we discuss the im...
0
Interleukin-1beta-mediated suppression of microRNA-27a-3p activity in human cartilage via MAPK and NF-kappaB pathways: A potential mechanism of osteoarthritis pathogenesis
OAK 3 - Non-arthroplasty tx of OAK
The aim of the present study was to investigate the role of microRNA (miR)-27a-3p in osteoarthritis (OA). Reverse transcription-quantitative polymerase chain reaction and western blotting were performed to determine the expression of miR-27a-3p and aggrecanase-2 (ADAMTS5) in cartilage tissues from patients with OA and ...
0
Safety of bilateral total knee arthroplasty in morbidly obese patients
PJI DX Updated Search
There has been an increase in the prevalence of morbid obesity and the demand for total knee arthroplasty (TKA). Physicians must help patients with bilateral knee arthritis to make informed decisions regarding whether to undergo staged, sequential, or simultaneous TKA. The purpose of this study was to evaluate the peri...
1
Relationship between stressfulness of claiming for injury compensation and long-term recovery: a prospective cohort study
DoD PRF (Psychosocial RF)
IMPORTANCE: Each year, millions of persons worldwide seek compensation for transport accident and workplace injuries. Previous research suggests that these claimants have worse long-term health outcomes than persons whose injuries fall outside compensation schemes. However, existing studies have substantial methodologi...
0
Quality of life implications of bisphosphonate-associated osteonecrosis of the jaw
MSTS 2018 - Femur Mets and MM
Purpose. Potentially debilitating, osteonecrosis of the jaw (ONJ) is an emerging complication of bisphosphonates. However, its effect on quality of life (QoL) is unknown. We determined the ONJ-related QoL decline in a cancer patient cohort. Patients and Methods. Thirty-four cancer patients with bisphosphonate-associate...
0
Body mass index change after knee replacement in the multicenter osteoarthritis study cohort
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Individuals with painful knee OA who undergo knee replacement (KR) are reported to have reduced pain and increased physical activity that might allow for subsequent weight reduction. However, a recent report of subjects who underwent a KR demonstrated a significant increase in body mass index (BMI) of approxim...
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Functioning free-muscle transplantation for the upper extremity
DoD - ACS - Interrater Reliability
Functioning free-muscle transplantation (FFMT) is an advanced microneurovascular technique indicated in patients who have an injury with major functional muscle or muscle group loss or denervation and no locally available or ideal musculotendinous donor units. Over the 9-year period, from 1986 to 1994, 47 FFMTs were ap...
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Global Prevalence and Preferences of Progressive Tension Suture Usage in Abdominoplasties
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Abdominoplasty is one of the most popular esthetic procedures. Seroma is the most frequent postoperative complication. Two decades of literature have described benefits of quilting sutures/progressive tension sutures (PTS) in reducing seroma rates and other complications in abdominoplasties. Despite this, P...
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Perioperative creatine phosphokinase trends in elderly patients with hip fracture
Management of Hip Fractures in the Elderly
A prospective study of the serum levels of unfractionated creatine phosphokinase (CPK) in 69 consecutive elderly patients undergoing surgery for hip fracture is reported. Serum unfractionated CPK levels were measured on admission, on the evening following surgery and daily for the first five days post-operatively. All ...
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Risk factors for superficial wound complications in hip and knee arthroplasty
AAHKS (2) Corticosteroids
Superficial wound complications have been consistently implicated in the development of prosthetic joint infection. This cohort study aimed to determine perioperative risk factors associated with superficial wound complications. The study was performed over an 18-month period (January 2011 to June 2012) and included 96...
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Does the Angle of the Nail Matter for Pertrochanteric Fracture Reduction? Matching Nail Angle and Native Neck-Shaft Angle
Hip Fx in the Elderly 2019
OBJECTIVES: To determine whether fixation of pertrochanteric hip fractures with cephalomedullary nails (CMNs) with a neck-shaft angle (NSA) less than the native NSA affects reduction and lag screw cutout. DESIGN: Retrospective comparative study. SETTING: Level I trauma center. PATIENTS/PARTICIPANTS: Patients treated wi...
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Mini-Open Posterior Compartment Release for Chronic Exertional Compartment Syndrome of the Leg
DOD - Acute Comp Syndrome CPG
Chronic exertional compartment syndrome (CECS) is a well-recognized cause of leg pain in endurance athletes. Surgical fasciotomy for posterior leg CECS historically has inferior clinical results compared with anterior and lateral compartment release. Poor surgical technique with inadequate release may contribute to les...
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Adverse effects of bisphosphonates
MSTS 2018 - Femur Mets and MM
Use of bisphosphonates has been growing steadily in the last decade. This follows the introduction of simpler dosing regimes, the availability of lower-priced generics, and concerns about the safety of hormone-replacement therapy. Bisphosphonates have a relatively good safety record and are tolerated by the majority of...
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Dry arthroscopy and its applications
Distal Radius Fractures
Wrist arthroscopy can be performed without infusing fluid, as simple traction suffices to maintain the working space. The lack of tissue infiltration by fluid keeps soft tissues in pristine condition if open surgery is needed after the arthroscopic exploration. The dry technique makes fluid distension irrelevant, thus ...
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Subchondral insufficiency fracture of the femoral head in a patient with alkaptonuria
PJI DX Updated Search
We report a patient with alkaptonuria accompanied by bilateral rapidly destructive arthrosis of the hip. The destruction of the left hip joint with its severe functional impairment necessitated total hip arthroplasty (THA). The outcome was satisfactory. Both magnetic resonance imaging (MRI) and pathologic findings were...
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The occipitofrontalis muscle is composed of two physiologically and anatomically different muscles separately affecting the positions of the eyebrow and hairline
Upper Eyelid and Brow Surgery
After the surgical correction of aponeurotic blepharoptosis or blepharoplasty, the positions of the eyebrow and hairline change as if the frontal belly is independent from the occipital belly of the occipitofrontalis muscle. Therefore, the occipitofrontalis muscle was studied physiologically with electromyographic eval...
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The outcome of operatively treated anterior cruciate ligament disruptions in the skeletally immature child
Anterior Cruciate Ligament Injuries CPG
The purpose of this study was to evaluate the outcome of transphyseal ligament reconstruction in skeletally immature children with midsubstance anterior cruciate ligament (ACL) disruption. Five consecutive patients (mean age, 12.9 years; range, 8 to 14 years) with radiographically documented "wide" open growth plates a...
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Clinical observation of 35 cases of pediatric Gartland ¢ó fractures of distal humerus treated with oral Cassia Twig decoction and manipulative reduction plus Kirschner wire fixation
Pediatric Supracondylar Humerus Fracture 2020 Review
Objective To observe the effect of oral Cassia Twig decoction and manipulative reduction with Kirschner wire fixation in the treatment of children with distal humeral Gartland III fracture. Methods 70 cases of children with distal humeral Gartland ¢ó fractures were randomly divided into treatment group and control gr...
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Analysis for apoptosis and necrosis on adipocytes, stromal vascular fraction, and adipose-derived stem cells in human lipoaspirates after liposuction
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Adipose-derived stem cells have become the most studied adult stem cells. The authors examined the apoptosis and necrosis rates for adipocyte, stromal vascular fraction, and adipose-derived stem cells in fresh human lipoaspirates. METHODS: Human lipoaspirate (n = 8) was harvested using a standard liposuctio...
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Total shoulder arthroplasty
Glenohumeral Joint OA
Shoulder arthroplasty has been the subject of marked advances over the last few years. Modern implants provide a wide range of options, including resurfacing of the humeral head, anatomic hemiarthroplasty, total shoulder arthroplasty, reverse shoulder arthroplasty and trauma-specific implants for fractures and nonunion...
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Early initiation of home-based sensori-motor training improves muscle strength, activation and size in patients after knee replacement: A secondary analysis of a controlled clinical trial
OAK 3 - Non-arthroplasty tx of OAK
Background: There is accumulating evidence for the advantages of rehabilitation involving sensori-motor training (SMT) following total knee replacement (TKR). However, the best way in which to deliver SMT remains elusive because of potential interference effects amongst concurrent exercise stimuli for optimal neuromusc...
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Deprivation influences the functional outcome from total hip arthroplasty
PJI DX Updated Search
Socioeconomic inequality through deprivation and access to healthcare is an aetiological factor in many disease processes. It is associated with the development of osteoarthritis, the need for joint arthroplasty and poorer access to secondary healthcare. Few studies have investigated the influence of deprivation on the...
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Safety and efficacy of methylprednisolone infiltration in anserine syndrome treatment
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: The anserine syndrome is a common cause of knee pain. Infiltration with glucocorticoids has been evaluated in studies with low level of evidence and there are no published clinical trials to determine its usefulness. The objective of this study was to determine the efficacy and safety of the infiltration of ...
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Focal knee resurfacing and effects of surgical precision on opposing cartilage. A pilot study on 12 sheep
OAK 3 - Non-arthroplasty tx of OAK
Background: Full thickness cartilage lesions (ICRS grade 3-4) and focal lesions of degenerative origin may progress to osteoarthritis (OA). Such focal lesions can be treated by metallic implants. We hypothesized that such treatment results in opposing surface cartilage damage that correlates with implant position (heig...
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Articular cartilage surface roughness as an imaging-based morphological indicator of osteoarthritis: A preliminary investigation of osteoarthritis initiative subjects
AMP (Acute Meniscal Pathology)
Current imaging-based morphometric indicators of osteoarthritis (OA) using whole-compartment mean cartilage thickness (MCT) and volume changes can be insensitive to mild degenerative changes of articular cartilage (AC) due to areas of adjacent thickening and thinning. The purpose of this preliminary study was to evalua...
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Multiple Low-Dose Dexamethasone Further Improves Clinical Outcomes Following Total Hip Arthroplasty
AAHKS (8) Anesthetic Infiltration
Background: The recommended dose regimen of dexamethasone in total hip arthroplasty (THA) has not been determined. This study was performed to assess the effects of multiple low-dose dexamethasone on clinical outcomes after THA. Methods: Two hundred ten patients undergoing THA received 3 doses of normal saline (Group A...