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Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): Study protocol for a randomised controlled trial
Hip Fx in the Elderly 2019
Introduction Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary methodology aiming to optimise individual medication therapy throughout the hospital stay. I...
0
Bone disease from monoclonal gammopathy of undetermined significance to multiple myeloma: pathogenesis, interventions, and future opportunities
MSTS 2018 - Femur Mets and MM
Manifestations of bone disease-osteopenia, osteolytic lesions, and fractures-are the hallmark of multiple myeloma (MM) and occur clinically in the vast majority of patients. These abnormalities can have devastating clinical effects by increasing both the morbidity and mortality of patients. Bone disease is usually foun...
0
Hip fracture outcomes: does surgeon or hospital volume really matter?
Management of Hip Fractures in the Elderly
BACKGROUND: Current data on the association between surgeon and hospital volumes and patient outcomes after hip fracture surgery is inconclusive. We hypothesized that surgeons and hospitals with higher caseloads of hip fracture care have better outcomes as measured by decreased postoperative complications and mortality...
0
Infection rate of intramedullary nailing for treatment of lower limb polyostotic fibrous dysplasia
DoD SSI (Surgical Site Infections)
Polyostotic fibrous dysplasia (PFD) generally cause deformities and fractures of femur and tibia and surgery is often required. The current surgical treatment for deformities is based on single or multiple osteotomies followed by stabilization with intramedullary nails, which are commonly used also for fractures. One o...
1
Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial
MSTS 2022 - Metastatic Disease of the Humerus
In the Prevention of Venous Thromboembolism Following Radical Prostatectomy (PREVENTER) randomized trial, pharmacologic prophylaxis did not reduce the rate of symptomatic (relative risk [RR] 0.40 [95% confidence interval {CI} 0.08–2.03], p = 0.267) or overall (RR 0.97 [95% CI 0.25–3.81], p = 0.967) venous thromboemboli...
0
Burden of hip fracture on inpatient care: a before and after population-based study
HipFx Supplemental Cost Analysis
SUMMARY: We estimated the excess hospital expenditure attributable to osteoporotic hip fracture (HF) within a population of 6,019 patients. Post-fracture excess of hospital days was 23.1, including 22.7 days in rehabilitation care. HF might result from a patient's pre-fracture poor health status rather than predispose ...
0
Factors predicting the efficacy of viscosupplementation in knee osteoarthritis
OAK Recommendation 9 Articles
a. Purpose: Previous research has demonstrated inconsistent effects of hyaluronic acid supplementation in patients with knee osteoarthritis (OA), and it is not known which patients will have the best clinical response to this therapy. The purpose of the present study is to evaluate some factors that may predict clinica...
1
Why are total knee replacements revised?: analysis of early revision in a community knee implant registry
Surgical Management of Osteoarthritis of the Knee CPG
Since 1991, 5760 knee arthroplasty procedures done by 53 surgeons have been registered in a community joint implant registry and were reviewed regarding initial revision done within the healthcare system. The 168 revisions done represented 2.9% of the knee arthroplasties between September 1991 and December 2002. Surviv...
0
Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients
AAHKS (2) Corticosteroids
Clinical risk factors (CRFs) are established predictors of fracture events. However, the influence of individual CRFs on trabecular mechanical fragility is still a subject of debate. In this study, we aimed to assess differences, adjusted for CRFs, between bone macrostructural parameters measured in ex-vivo specimens f...
0
Surgical treatment of gynecomastia with severe ptosis: Periareolar incision and dermal double areolar pedicle technique
Panniculectomy & Abdominoplasty CPG
Background: Gynecomastia is a morphostructural impairment of the mammary region in men caused by parenchymal hypertrophy or a cutaneous distortion of breast skin covering or both. The clinical classification introduced by Simon et al. in 1973 ranks gynecomastia in three degrees. Each subtype can be treated with a speci...
0
A brief history of plastic surgery in Iran
Panniculectomy & Abdominoplasty CPG
Although the exact time of performing plastic surgery is not addressed in the medical and historical literature, it can be supposed that these surgical procedures have a long and fascinating history. Recent excavations provided many documents regarding the application of medical instruments, surgical and even reconstru...
0
Modification of subcutaneous adipose tissue by a methylxanthine formulation: A double-blind controlled study
Panniculectomy & Abdominoplasty CPG
BACKGROUND. Excessive subcutaneous adipose tissue is typically treated by physically removing the fat through liposuction, but cost and accessibility have popularized alternative treatments for reducing adipose tissue thickness. OBJECTIVE. The purpose of this study was to test the absolute and relative effectiveness of...
0
Lateral patellar tilt and its longitudinal association with patellofemoral osteoarthritis-related structural damage: Analysis of the osteoarthritis initiative data
AMP (Acute Meniscal Pathology)
Background: Increase in lateral patellar tilt-(LPT) can cause increased pressure on the lateral facet of the knee and can lead to patellar or femoral cartilage damage and further osseous changes. This study aims to test the hypothesis whether there is an association between increased LPT and MRI-based patellofemoral os...
0
Predictors of not regaining basic mobility after hip fracture surgery
Hip Fx in the Elderly 2019
PURPOSE: Regaining basic mobility after hip fracture surgery is a milestone in the in-hospital rehabilitation. The aims were to investigate predictors for not regaining basic mobility at the fifth post-operative day and at discharge after undergoing hip fracture surgery. METHOD: In a prospective cohort study 274 hip fr...
0
Dispensable role of myeloid differentiation primary response gene 88 (MyD88) and MyD88-dependent toll-like receptors (TLRs) in a murine model of osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Objectives: The aim of our study was to evaluate the role of cell-membrane expressed TLRs and the signaling molecule MyD88 in a murine model of OA induced by knee menisectomy (surgical partial removal of the medial meniscus [MNX]). Methods: OA was induced in 8-10. weeks old C57Bl/6 wild-type (WT) female (n= 7) mice and...
1
Use and satisfaction with prosthetic devices among persons with trauma-related amputations: a long-term outcome study
DoD LSA (Limb Salvage vs Amputation)
OBJECTIVE: To document and examine the use, satisfaction, and problems with prosthetic devices among persons who suffered a trauma-related lower limb amputation. DESIGN: Abstracted medical records and follow-up interview data were collected for a retrospective cohort of persons with a lower limb trauma-related amputati...
0
Identification of Discrete Prognostic Groups in Ewing Sarcoma
MSTS 2022 - Metastatic Disease of the Humerus
Background: Although multiple prognostic variables have been proposed for Ewing sarcoma (EWS), little work has been done to further categorize these variables into prognostic groups for risk classification. Procedure: We derived initial prognostic groups from 2,124 patients with EWS in the SEER database. We constructed...
0
Bicipital tuberosity bone characteristics in surgical reattachment of the distal biceps: anatomical and radiological study
Distal Radius Fractures
PURPOSE: The aim of this study was to measure the cortical thickness and bone density of the different parts of the bicipital tuberosity, to evaluate the importance of these variables on resistance to pulling out of distal biceps tendon reinsertion implants. METHODS: Sixteen cadaveric arms were used for this study. A m...
0
Identification of a subgroup of patients at highest risk for complications after surgical cytoreduction and hyperthermic intraperitoneal chemotherapy
DOD - Acute Comp Syndrome CPG
OBJECTIVE: To assess the influence of parietal and visceral peritonectomy procedures on moderate/severe morbidity in patients undergoing surgical cytoreducion and hyperthermic intraperitoneal chemotherapy (HIPEC) and to identify subgroups of patients at highest operative risk. BACKGROUND: Cytoreducion with HIPEC is an ...
0
Arthroscopic Partial Trapeziectomy With Soft Tissue Interposition for Symptomatic Trapeziometacarpal Arthritis: 6-Month and 5-Year Minimum Follow-Up
Glenohumeral Joint OA
PURPOSE: To determine if arthroscopic partial trapeziectomy (APT) and soft tissue interposition arthroplasty is an effective treatment for symptomatic trapeziometacarpal arthritis. METHODS: We retrospectively evaluated 30 consecutive patients with symptomatic isolated trapeziometacarpal arthritis, Eaton-Littler stages ...
0
Comparative safety of endovascular aortic aneurysm repair over open repair using patient safety indicators during adoption
Hip Fx in the Elderly 2019
IMPORTANCE In 2003, the Agency for Healthcare Research and Quality established Patient Safety Indicators (PSIs) to monitor preventable adverse events during hospitalizations. Copyright 2014 American Medical Association. All rights reserved. OBJECTIVE To evaluate the comparative safety of endovascular aneurysm repair (E...
0
Do all hip fractures result from a fall?
Management of Hip Fractures in the Elderly
Although most fractures of the proximal femur result from a fall and are related to direct loads to the hip, there is evidence that intrinsic factors, such as muscle contraction, can result in a hip fracture and subsequent fall. This paper reviews the current literature on the various mechanisms of femoral neck and int...
1
The Use of TIGR Matrix in Breast Aesthetic and Reconstructive Surgery: Is a Resorbable Synthetic Mesh a Viable Alternative to Acellular Dermal Matrices?
Acellular Dermal Matrix
The authors document their experience in the use of synthetic 100% bioresorbable surgical mesh (TIGR Matrix, Novus Scientific, Uppsala, Sweden) in breast reconstruction as well as in breast aesthetic surgery. They performed a retrospective review on patients who underwent implant-based breast reconstruction as well as ...
0
Long-term results of the ludloff procedure in relation to the intraoperative finding on acetabular labrum
Developmental Dysplasia of the Hip 2020 Review
PURPOSE OF THE STUDY Developmental dysplasia of the hip still remains one of the most discussed topics in paediatric orthopaedics. The comprehensive care of paediatric patients with congenital developmental dysplasia of the hip at our department in the period from 1970 to 1985 included, among other things, the open red...
0
Assessment of renal toxicity and osteonecrosis of the jaws in patients receiving zoledronic acid for bone metastasis
MSTS 2018 - Femur Mets and MM
BACKGROUND: Bisphosphonates (BP) decrease the incidence of skeletal related events among cancer patients with bone metastases from solid tumors and multiple myeloma. Renal safety and osteonecrosis of the jaws (ONJ) are two major concerns of toxicity. Information about safety of using BP beyond 2 years is scarce. MATERI...
0
Clinical anatomy in aesthetic gluteal body contouring surgery
Panniculectomy & Abdominoplasty CPG
This article describes some of the major anatomical issues that confront plastic surgeons when contouring and augmenting the gluteal region. A better understanding of anatomy can improve the cosmetic results of gluteal augmentation and thereby enhance patient satisfaction. More importantly, this knowledge can reduce th...
0
Reverse shoulder arthroplasty in acute fractures of the proximal humerus: A systematic review
PJI DX Updated Search
The indications for surgical intervention in complex fractures of the proximal humerus are disputed. In elderly patients with poor bone stock it may be impossible to obtain satisfactory fixation of the tuberosities to a hemiarthroplasty (HA). In such cases primary insertion of a reverse shoulder arthroplasty (RSA) has ...
0
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis
Management of Hip Fractures in the Elderly
Osteoporosis, a highly heritable disease, is characterized mainly by low bone-mineral density (BMD), poor bone geometry, and/or osteoporotic fractures (OF). Copy-number variation (CNV) has been shown to be associated with complex human diseases. The contribution of CNV to osteoporosis has not been determined yet. We co...
0
Image classification for Die-punch fracture of intermediate column of the distal radius
Distal Radius Fractures
OBJECTIVE: The aim of the study was to analyze the imaging findings of Die-punch fracture of intermediate column of the distal radius, and to explore the clinical application value of image classification. METHODS: The clinical data of 45 patients who were admitted to our hospital from May 2010 to October 2016 were ana...
0
Incidence of Meniscal Entrapment and Associated Knee Injuries in Tibial Spine Avulsions
AMP (Acute Meniscal Pathology)
BACKGROUND: Tibial spine avulsions (TSA) have historically been treated as isolated injuries. Data on associated injuries are limited with existing literature reporting wide ranging incidences. The purpose of this multicenter study was to (1) describe the incidence of meniscal entrapment and associated knee injuries in...
0
The accuracy of self-reported fractures in older people
Management of Hip Fractures in the Elderly
Self-report is often used in large-scale studies. Therefore, it is important to determine the accuracy of self-report. In the Blue Mountains Eye Study, a population-based study of 3,654 older, community-dwelling Australians, subjects were asked about fracture history at the 5-year follow-up interview. All reported non-...
0
Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: The aim of this study was to investigate the effect of endogenous matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) on the invasive characteristics of RA synovial fibroblasts. METHODS: Synovial fibroblasts isolated from patients with RA or OA were treated with MMP small interfering RNA (siRNA), inhibitors ...
0
Obesity, metabolic abnormality, and knee osteoarthritis: a cross-sectional study in Korean women
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: This study aimed to analyze the association between knee osteoarthritis and four body size phenotypes defined by the presence or absence of metabolic abnormality and obesity. MEHODS: This was a cross-sectional study using data from 1,549 female participants of the Fifth Korean National Health and Nutrition ...
0
Supracondylar elbow fractures with impaction of the medial condyle in children
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
We reviewed the cases of 13 children with supracondylar elbow fractures with impaction of the medial wall. The displacement was underestimated in two patients and treated as a minimally displaced fracture by simple immobilization without reduction, resulting in a cubitus varus deformity. In one patient, the correct dia...
0
Large autologous ilium with periosteum for tibiotalar joint reconstruction in Ruedi-Allgower III or AO/OTA type C3 pilon fractures: a pilot study
DoD SSI (Surgical Site Infections)
BACKGROUND: Management of Ruedi-Allgower III or AO/OTA type C3 pilon fracture presents numerous challenges to the orthopaedic surgeon. A joint preservation technique using a large autologous ilium with periosteum in combination with internal implant fixation was reported to improve the outcome of reconstruction. METHOD...
0
Migraine and risk of dementia: A nationwide retrospective cohort study
DoD PRF (Psychosocial RF)
Objective: Migraines are one of the most common neurological disorders. Dementia is a neurodegenerative disease characterized by slow progressive memory loss and cognitive dysfunction. This retrospective cohort study investigates the association between migraines and dementia using a nationwide population-based databas...
0
Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group
Management of Hip Fractures in the Elderly
To determine whether magnetic resonance (MR)-derived measures of trabecular bone architecture in the distal radius are predictive for prevalent hip fractures, 20 subjects with hip fractures and 19 age-matched postmenopausal controls were studied. Bone mineral density (BMD) measures at the hip (dual-energy X-ray absorpt...
1
Lack of effect of orally administered human serum immunoglobulin on the normal human oral and intestinal microflora
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The aim of this study was to investigate the influence of large doses of orally administered human IgG on the normal gastrointestinal microflora of healthy volunteers since human immunoglobulin has been tried as oral prophylaxis and therapy in gastrointestinal infections. Ten adult healthy volunteers received 10 g of I...
0
Trochanteric osteotomy versus posterolateral approach: function the first year post surgery. A pilot study
Management of Hip Fractures in the Elderly
Although no prospective studies have compared functional results of trochanteric osteotomy and a non-trochanteric approach, most surgeons feel that trochanteric osteotomy is outdated in simple hip arthroplasty. Reasons not to perform an osteotomy include the fear of longer rehabilitation and worse (final) functional ou...
0
Renal failure in multiple myeloma: reversibility and impact on the prognosis. Nordic Myeloma Study Group
MSTS 2018 - Femur Mets and MM
The purpose of the present study was to analyse the importance and prognostic value of renal failure in multiple myeloma patients. The frequency and reversibility of renal failure in 775 multiple myeloma patients diagnosed between 1984-86 and 1990-92 in the Nordic countries were studied. Renal failure, defined as plasm...
0
Role of Arthroscopy in the Treatment of Osteoarthritis of Knee
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: A variety of procedures have been described for treatment of the osteoarthritic knee. Comprehensive Arthroscopic treatment regime has definite role in treating patients with knee Osteoarthritis. AIM: To evaluate the role of arthroscopy in functional and subjective outcomes of patient with moderate to severe...
1
Roentgen stereophotogrammetric analysis and clinical assessment of unipolar versus bipolar hemiarthroplasty for subcapital femur fracture: a randomized prospective study
Management of Hip Fractures in the Elderly
BACKGROUND: Hemiarthroplasty is a well-established treatment for displaced subcapital fracture, but controversy exists about the optimal implant type. Bipolar hemiarthroplasty has proposed advantages over unipolar hemiarthroplasty in terms of better clinical results and decreased wear of acetabular cartilage. METHODS: ...
1
Titanium Elastic Nailing has Superior Value to Plate Fixation of Midshaft Femur Fractures in Children 5 to 11 Years
Pediatric Diaphyseal Femur Fractures 2020 Review
BACKGROUND: American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guidelines for pediatric femoral shaft fractures indicate titanium elastic nails (TENs) for children 5 to 11 years old. Growing evidence suggests these fractures may also be treated with open or submuscular plating. The purpose of this study ...
1
Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To determine whether there is sufficient evidence to conclude that exercise interventions are more effective than no exercise control and to compare the effectiveness of different exercise interventions in relieving pain and improving function in patients with lower limb osteoarthritis. DATA SOURCES: Nine el...
1
Self-reported health status of students in-processing into military medical advanced individual training
DoD PRF (Psychosocial RF)
It is important to be aware of the health and injury status of students in military training settings in order to adequately plan for their progression through required physical training and provision of health care to meet their needs. This paper describes the self-reported health status of students arriving in two me...
0
Unreconstructable acute distal humeral fractures and their sequelae treated with distal humeral hemiarthroplasty: a two-year to eleven-year follow-up
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
BACKGROUND: The aim of this study was to describe for the first time the medium to long-term outcome after distal humeral hemiarthroplasty (DHH). METHODS: Twenty-six patients (mean age, 62; range, 29-92 years) treated with DHH for intra-articular distal humeral fractures and its sequelae were studied retrospectively. R...
0
Lower extremity overuse injuries in the skeletally immature athlete
Osteochondritis Dissecans 2020 Review
Sport participation is a leading cause of injury in children and adolescents. Although the focus often is on acute injuries, overuse injuries are extremely common and can cause lasting damage when not recognized early and treated appropriately. Overuse injuries result from the combination of repetitive microtrauma and ...
0
Fluconazole prophylaxis in extremely low birth weight neonates reduces invasive candidiasis mortality rates without emergence of fluconazole-resistant candida species
Patrick’s pharmacoepidemiology project
Objective. We evaluated the impact of fluconazole prophylaxis for extremely low birth weight infants on invasive candidiasis incidence, invasive candidiasis-related mortality rates, and fluconazole susceptibility of Candida isolates. Methods. Extremely low birth weight infants <5 days of age, except those with liver dy...
0
Activity-Related Outcomes of Articular Cartilage Surgery: A Systematic Review
SR for PM on OA of All Extremities
Objective: The purpose of this systematic review was to compare activity-based outcomes after microfracture, autologous chondrocyte implantation (ACI), and osteochondral autograft (OAT). Design: Multiple databases were searched with specific inclusion and exclusion criteria for level III and higher studies with activit...
0
Surgery for plasma cell neoplasia patients with spinal instability or neurological impairment caused by spinal lesions as the first clinical manifestation
MSTS 2018 - Femur Mets and MM
Purpose: Multiple myeloma (MM) and solitary plasmacytoma of bone (SPB) are two independent subtypes of plasma cell dyscrasias which often occur in spine. However, little is known about the surgical treatment of patients with spinal instability or neurological impairment caused by spinal lesions as the first clinical ma...
0
Temporal in vitro expansion of the luminal lineage of human mammary epithelial cells achieved with the 3T3 feeder layer technique
Reduction Mammoplasty for Female Breast Hypertrophy
Human mammary epithelial cells from reduction mammoplasties were serially propagated in vitro from single cells and/or cell clusters using the NIH 3T3 cell feeder layer technique. In seven passages 46 cell population doublings, corrected for plating efficiency were achieved. The plating efficiency of epithelial cells i...
0
Postmenopausal women with Colles' fracture have lower values of bone mineral density than controls as measured by quantitative ultrasound and densitometry
Management of Hip Fractures in the Elderly
Measurement of ultrasonographic parameters provides information concerning not only bone density but also bone architecture. We investigated the usefulness of ultrasonographic parameters and bone mineral density (BMD) to evaluate the probability of Colles' fracture. Two-hundred eighty-nine postmenopausal women (62.3 (p...
0
Localized development of knee osteoarthritis can be predicted from MR imaging findings a decade earlier
AMP (Acute Meniscal Pathology)
PURPOSE: To define localized development of knee osteoarthritis (OA) that arises from anterior cruciate ligament (ACL) and meniscal injuries identified at magnetic resonance (MR) imaging performed a decade ago and the subsequent management of those findings in patients with subacute knee symptoms. MATERIALS AND METHODS...
1
Physical therapies for improving balance and reducing falls risk in osteoarthritis of the knee: a systematic review
OAK 3 - Non-arthroplasty tx of OAK
INTRODUCTION: osteoarthritis (OA) of knee has been reported as a risk factor for falls and reduced balance in the elderly. This systematic review evaluated the effectiveness of physical therapies in improving balance and reducing falls risk among patients with knee OA. METHODS: a computerised search was performed to id...
0
Stationary potentials after median nerve stimulation: Changes with arm position
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
We previously reported the presence of stationary negative potentials (N3, N6, N9) over the arm ipsilateral to the side of median nerve stimulation. In this study, we examined the effect of different arm positions upon these stationary peaks in 12 normal subjects. When arm position was changed from elbow extended to el...
0
Hemodialysis-associated carpal tunnel syndrome. A clinical review
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The clinical features of 88 patients who developed carpal tunnel syndrome (CTS) in association with end stage renal failure and chronic hemodialysis were studied (11 original cases and 77 collected from the literature). Hemodialysis-associated CTS was found to have a 2 to 1 male predominance, to occur more often in ang...
0
Leptotrichia species in human infections
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Leptotrichia species typically colonize the oral cavity and genitourinary tract. These anaerobic bacteria belong to the normal flora of humans and are seldom found in clinically significant specimens. However, on rare occasions, Leptotrichia has been isolated from blood cultures of patients with lesions in the oral muc...
1
Limited short-term effect of palliative radiation therapy on quantitative computed tomography-derived bone mineral density in femora with metastases
MSTS 2018 - Femur Mets and MM
Purpose The aim of this study was to determine the effect of single fraction (SF) and multiple fraction (MF) radiation therapy (RT) on bone mineral density (BMD) in patients with cancer and bone metastases in the proximal femur. We studied this effect in the radiation field and within metastatic lesions, and differenti...
0
Clinical and arthrographic findings in meniscal cysts
AMP (Acute Meniscal Pathology)
Fifty meniscal cysts (36 lateral and 14 medial) were found in a review of 2,522 knee arthrograms. Thirty-eight cysts presented as a palpable bulge. In all cases characteristic horizontal tears extended into the periphery, with pooling of contrast material and club-shaped terminations. The differential diagnosis of a bu...
0
Serum cathepsin B and plasma urokinase-type plasminogen activator levels in gastrointestinal tract cancers
MSTS 2018 - Femur Mets and MM
Cathepsin B (CATB) and urokinase-type plasminogen activator (UPA) play an important part in cancer invasion and metastasis. The behavior of CATB and UPA has not been evaluated in the same experimental setting in different gastrointestinal tumors and in precancerous lesions. Serum CATB and plasma UPA levels were determi...
0
Missing data may lead to changes in hip fracture database studies: A study of the American college of surgeons national urgical quality improvement program
DoD SSI (Surgical Site Infections)
Aims The aims of this study were to characterize the frequency of missing data in the National Surgical Quality Improvement Program (NSQIP) database and to determine how missing data can influence the results of studies dealing with elderly patients with a fracture of the hip. Patients and Methods Patients who underwen...
0
The assessment of postural control with stochastic resonance electrical stimulation and a neoprene knee sleeve in the osteoarthritic knee
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To determine whether the combination of stochastic resonance (SR) electrical stimulation and a neoprene knee sleeve could improve center of pressure (COP) measures of postural sway during single-leg stance in those with knee osteoarthritis (OA). DESIGN: Counterbalanced, repeated-measures intervention study o...
0
Split gluteal muscle flap for autoprosthesis buttock augmentation
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Several flaps have been described to provide autologous augmentation to the gluteal area. Since the authors' original description of a dermal fat flap for buttock augmentation during lower body lift in 2005, the procedure has been refined considerably. Unique to previously described flaps, the technique res...
0
Periodontal diagnosis: evaluation of current concepts and future needs
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Periodontal diseases are multifactorial pathologies that manifest clinically by destruction of the soft and hard tissues. Bacterial insult has been implicated in the initiation of these diseases, however the degree of destruction is dependent on the host response. The host response varies from individual to individual ...
0
Intramuscular corticosteroid injection versus placebo effective in pain reduction in patients with hip osteoarthritis
PJI DX Updated Search
Purpose: Several international guidelines recommend intra-articular (IA) corticosteroid injections for patients with hip OA experiencing moderate to severe pain and no responding to oral analgesics. However, injection into the hip joint is challenging and needs ultrasound or fluoroscopic guidance. This makes it almost ...
0
Spontaneous resolution of soft-tissue interposition after closed reduction of hip endoprosthesis dislocation
Management of Hip Fractures in the Elderly
Over a 5-year period at a single institution, 164 endoprostheses were used for the treatment of displaced femoral neck fractures. Soft-tissue restraint preservation and repair (hip capsule and labrum) is recommended to enhance stability after endoprosthesis placement. When dislocation does occur, however, this soft tis...
1
Clinical effects of thai herbal compress: a systematic review and meta-analysis
OAK 3 - Non-arthroplasty tx of OAK
Objective . To determine the clinical effects of Thai herbal compress.
0
Segmental proximal femoral bone loss and revision total hip replacement in patients with developmental dysplasia of the hip: the role of allograft prosthesis composite
PJI DX Updated Search
The treatment of substantial proximal femoral bone loss in young patients with developmental dysplasia of the hip (DDH) is challenging. We retrospectively analysed the outcome of 28 patients (30 hips) with DDH who underwent revision total hip replacement (THR) in the presence of a deficient proximal femur, which was re...
0
Noninvasive measurement of distal radius instability
Distal Radius Fractures
Except for subjective clinical criteria, there is no formal definition of distal radius fracture instability in the literature. The purposes of this ex vivo biomechanical study were (1) to provide an objective mechanical definition of fracture instability and (2) to demonstrate a noninvasive method that allows for dire...
0
Developing a strategy to treat established infection in total knee replacement: a review of the latest evidence and clinical practice
PJI DX Updated Search
This review summarises the opinions and conclusions reached from a symposium on infected total knee replacement (TKR) held at the British Association of Surgery of the Knee (BASK) annual meeting in 2011. The National Joint Registry for England and Wales reported 5082 revision TKRs in 2010, of which 1157 (23%) were caus...
0
Meniscal and chondral loss in the anterior cruciate ligament injured knee
AMP (Acute Meniscal Pathology)
Rupture of the anterior cruciate ligament (ACL) of the knee is a commonly occurring injury in the athletic population. Associated meniscal and chondral injury is well recognised. This occurs both at the time of index injury and also secondarily over time in the ACL-deficient knee as a result of several related pathways...
0
Effects of risedronate or alfacalcidol on bone mineral density, bone turnover, back pain, and fractures in Japanese men with primary osteoporosis: results of a two-year strict observational study
Distal Radius Fractures
Although osteoporosis in men is already a major public health problem, there is still a dearth of data about the effects of risedronate in male osteoporosis, especially in Japanese with primary osteoporosis. Therefore, the objective of our study was to investigate the effects of risedronate on bone mineral density (BMD...
1
Diagnosis of compressive and entrapment neuropathies of the upper extremity: Value of MR imaging
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Compressive and entrapment neuropathies (CENs) are relatively common clinical syndromes characterized by neurologic manifestations caused by mechanical or dynamic compression of peripheral nerves. Radiologists are often required to evaluate CENs primarily to rule out soft-tissue lesions as a potential cause of the synd...
0
Glycosaminoglycan distribution in cartilage as determined by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC): potential clinical applications
AMP (Acute Meniscal Pathology)
OBJECTIVE: We sought to describe a range of in vivo observations of glycosaminoglycan distribution in knee cartilage using the delayed gadolinium-enhanced MRI of cartilage technique. CONCLUSION: The index of glycosaminoglycan distribution, T1(Gd), can exceed 500 msec (denoting high glycosaminoglycan) or can be less tha...
1
Supracondylar humeral osteotomy in children with severe posttraumatic cubitus varus deformity
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
The authors report the results of corrective osteotomy of the humerus in 11 children with severe posttraumatic cubitus varus deformity. The average carrying angle on the affected side was -24.4(degrees), and there was an average internal rotation deformity of the distal humerus of 22(degrees). Flexion and extension of ...
0
Prevention of heterotopic ossification with irradiation after total hip arthroplasty. Radiation therapy with a single dose of eight hundred centigray administered to a limited field
Management of Hip Fractures in the Elderly
Sixty-two hips in fifty-five patients who were considered to be at risk for postoperative heterotopic ossification were randomly divided into two groups: one received a single 800-centigray dose of limited-field radiation and the other, 1000 centigray of limited-field radiation in divided doses. The risk for heterotopi...
0
The use of focused ultrasound for non-invasive body contouring in Asians
Panniculectomy & Abdominoplasty CPG
Introduction: Previous studies demonstrated that multiple treatments using focused ultrasound can be effective as an non-invasive method for reducing unwanted localized fat deposits. The objective of the study is to investigate the safety and efficacy of this focused ultrasound device in body contouring in Asians. Meth...
0
Knee arthroplasty in Kuwait during 25 years: A national presentation and an international review
Surgical Management of Osteoarthritis of the Knee CPG
Since 1984, 577 knee arthroplasty operations were performed in Al Razi Orthopedic hospital in Kuwait. An increase in the number of these operations occurred during the last four years and in 2007 there were almost 100 knee arthroplasty operations performed. Six out of seven operated patients were female. The mean age a...
0
High Tibial Osteotomy and Medial Meniscus Transplant
AMP (Acute Meniscal Pathology)
Concomitant high tibial osteotomy and meniscal allograft transplant is indicated in patients with medial meniscus deficiency and varus deformity. A synergistic relationship likely exists between knee realignment and restoration of meniscal and chondral tissue. Therefore, it is important to address all sources of pathol...
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Bone Metastasis in Renal Cell Carcinoma Patients: Risk and Prognostic Factors and Nomograms
MSTS 2022 - Metastatic Disease of the Humerus
Background: Bone metastasis (BM) is one of the common sites of renal cell carcinoma (RCC), and patients with BM have a poorer prognosis. We aimed to develop two nomograms to quantify the risk of BM and predict the prognosis of RCC patients with BM. Methods: We reviewed patients with diagnosed RCC with BM in the Surveil...
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Subcutaneous Direct-to-Implant Breast Reconstruction: Surgical, Functional, and Aesthetic Results after Long-Term Follow-Up
Acellular Dermal Matrix
Direct-to-implant breast reconstruction can be achieved more easily by means of soft-tissue replacement devices such as dermal matrices and synthetic meshes. The feasibility of a subcutaneous approach has been recently investigated by some studies with different devices functioning as implant support. Aim of this study...
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Risk of institutionalization following fragility fractures in older people
Pediatric Supracondylar Humerus Fracture 2020 Review
Summary: Previously independent living older people suffering fractures of the hip have a high risk of new admission to a nursing home during the subsequent months. This study shows that older people admitted to hospital for fractures of the pelvis and spine have a similar risk of admission to a nursing home. Introduct...
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Post-operative medical and surgical complications after primary total joint arthroplasty in solid organ transplant recipients: a case series
OAK 3 - Non-arthroplasty tx of OAK
Purpose: In a series of solid organ transplant (SOT) recipients who underwent a subsequent primary total joint arthroplasty (TJA) procedure, this study aimed to determine: (1) 90-day morbidity and mortality after primary total knee or hip arthroplasty (TKA and THA), (2) overall post-operative infection rates, and (3) h...
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Effect of Mode of Femoral Nerve Analgesia on Quadriceps Muscle Strength
AAHKS (8) Anesthetic Infiltration
Continuous femoral nerve analgesia technique is relatively safe, can be easily trained, and reduces significantly intravenous opioid consumption. These favorable features make it standard treatment option for postoperative knee pain. However, direct perineural local anesthetic effect is not only confined into pain fibe...
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Canaletto implant in revision surgery for carpal tunnel syndrome: 21 case series
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Revision carpal tunnel surgery varies from 0.3% to 19%. It involves a delayed neurolysis and prevention of perineural fibrosis. Despite numerous available procedures, the results remain mediocre. The aim of this study is to evaluate the results of the Canaletto implant in this indication. Our series includes 20 patient...
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Stationary negative potentials near the source vs. positive far-field potentials at a distance
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
We studied the field distribution of referentially recorded negative potentials after stimulation of the median nerve at the wrist in 15 normal subjects. When recorded from multiple sites along the lateral aspect of the arm with the reference electrode at the knee, 3 negative peaks, N3, N6 and N9, appeared at fixed lat...
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Pneumonectomy in pulmonary metastasis
MSTS 2022 - Metastatic Disease of the Humerus
Background: The risk of complication following pneumonectomy is high; therefore, the decision to perform pneumonectomy should be carefully evaluated. A retrospective multicenter study of patients with metastatic lung tumors who underwent pneumonectomy was conducted. Methods: The database from the Metastatic Lung Tumor ...
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Effect of repeated manipulation on range of motion in patients with stiff total knee arthroplasty
OAK 3 - Non-arthroplasty tx of OAK
Although manipulation under anesthesia (MUA) has been considered effective firstline treatment for stiff total knee arthroplasty (TKA), there is no consensus regarding the usefulness of repeated MUA. The purpose of this study was to investigate the usefulness of repeated MUA performed for patients in whom satisfactory ...
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Compass hinge fixator for acute and chronic instability of the elbow
Distal Radius Fractures
OBJECTIVE: To maintain concentric reduction of an unstable elbow and to allow active exercises after the treatment of complex elbow injuries or their sequelae. INDICATIONS: Recurrent dislocation or subluxation of the elbow after repair or reconstruction of bony, capsuloligamentous, and/or musculotendinous stabilizers. ...
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Neuropathic-Like Pain Symptoms in a Community-Dwelling Sample with or at Risk for Knee Osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To characterize neuropathic-like pain among individuals with or at risk for knee osteoarthritis. SUBJECTS: One hundred eighty-four individuals who self-identified as non-Hispanic black or non-Hispanic white and presented with unilateral or bilateral knee pain. DESIGN: Neuropathic-like pain was assessed using...
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Safe Plastic Surgery of the Breast II: Saving Nipple Sensation
Reduction Mammoplasty for Female Breast Hypertrophy
<b>Background:</b> Since its inception, reduction mammoplasty has matured considerably. Primary evolution in clinical research and practice initially focused on developing techniques to preserve tissue viability; breast parenchyma, skin, and nipple tissue that has expanded to include sensation and erectile function pla...
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Different ways to treat subtrochanteric fractures with the Medoff sliding plate
Management of Hip Fractures in the Elderly
Thirty-two consecutive subtrochanteric fractures in 32 patients were stabilized using the Medoff sliding plate and were followed up prospectively for 1 year. Two patients died during the first postoperative year. Twenty-nine of the remaining 30 (97%) fractures united by 1-year followup. Two types of plate dynamization ...
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A Comparison of the Contact Force Distributions on the Acetabular Surface Due to Orthopedic Treatments for Developmental Hip Dysplasia
Developmental Dysplasia of the Hip 2020 Review
We used a three-dimensional rigid body spring model (RBSM) to compare the contact force distributions on the acetabular surface of the infant hip joint that are produced by three orthopedic treatments for developmental dysplasia of the hip (DDH). We analyzed treatments using a Pavlik harness, a generic rigid splint, an...
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Galeazzi fracture-dislocation: a new treatment-oriented classification
Distal Radius Fractures
Forty patients with Galeazzi fracture-dislocations were treated with open reduction and internal fixation of the radial shaft fracture. Intraoperative distal radioulnar joint (DRUJ) instability after anatomic reduction was managed with supplemental wire transfixion of the DRUJ (10 patients) or open reduction and triang...
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Usefulness of meniscal width to transverse diameter ratio on coronal MRI in the diagnosis of incomplete discoid lateral meniscus
AMP (Acute Meniscal Pathology)
AIM: To evaluate the clinical utility of the meniscal width to transverse diameter ratio (L/M ratio) of the lateral meniscus in the diagnosis of incomplete discoid lateral meniscus (IDLM) as compared with the arthroscopic diagnosis, meniscal width to tibial diameter ratio (L/T ratio) and conventional lateral meniscus w...
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Rest-activity patterns and falls and fractures in older men
Hip Fx in the Elderly 2019
Summary: Dysregulated rest-activity rhythm (RAR) patterns have been associated with several health conditions in older adults. This study showed that later acrophase was associated with a modestly greater risk of falls but not fractures in elderly men. Associations between dysregulated RAR patterns and osteoporosis ris...
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Minimally invasive unicondylar arthroplasty in the post-meniscectomy knee: Repicci knee
AMP (Acute Meniscal Pathology)
Loss of the meniscus decreases contact area, resulting in increased stress on the articular cartilage of the knee. Osteoarthritis frequently develops and sclerotic bone is exposed on the articular surfaces of the joint. In the medial compartment, this process is characterized by loss of articular cartilage and anterior...
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Arthroscopic treatment of acute patellar dislocations
AMP (Acute Meniscal Pathology)
Twenty-nine patients treated with arthroscopy alone for acute patellar dislocation were reviewed. All had a significant traumatic episode with hemarthrosis in a previously asymptomatic knee. Clinical follow-up averaged 25 months (range 5-64 months). Fifteen patients had concomitant percutaneous lateral release (LR). Si...
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Knee osteoarthritis and exercise adherence: a review
OAK 3 - Non-arthroplasty tx of OAK
Individuals with knee osteoarthritis, a painful debilitating joint disease affecting many aging adults, are commonly encouraged to pursue a variety of exercise regimens. However, very few studies have specifically focused on barriers and facilitators of exercise adherence as related to knee osteoarthritis. This review ...
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Psychosocial factors associated with physical activity in ambulatory and manual wheelchair users with spinal cord injury: A mixed-methods study
DoD PRF (Psychosocial RF)
Purpose: To identify psychosocial factors which explain lower levels of leisure time physical activity (LTPA) in persons with spinal cord injury (SCI) who are ambulatory relative to those who use manual wheelchairs. Method: For the quantitative study component, 347 adults with SCI (78% male; M age = 47.7) completed bas...