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Do physicians' implicit views of African Americans affect clinical decision making?
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Total knee replacement (TKR) is a cost-effective treatment option for severe osteoarthritis (OA). While prevalence of OA is higher among blacks than whites, TKR rates are lower among blacks. Physicians' implicit preferences might explain racial differences in TKR recommendation. The objective of this study ...
0
The Short Term Effect of Hot Packs and Whirlpool for Increasing Total Active Motion at the Wrist
Distal Radius Fractures
This study investigates the short term effect of hot packs versus whirlpool and exercise for patients with distal radius fracture (DRF) during a therapy visit. Patients with recently healed DRF are randomized into two groups, with one group receiving hot packs during therapy and the other immersing the arm in a whirlpo...
0
A pilot randomized control trial of aerobic cycling before total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: The main purpose of the study was to determine if a full trial of an aerobic cycling program for pre TKA (total knee arthroplasty) patients was feasible, by assessing recruitment, safety, ability to cycle, program adherence and aerobic benefit. Secondary objectives were to estimate sample size for a future ful...
0
Influence of low back pain on total knee arthroplasty outcome
OAK 3 - Non-arthroplasty tx of OAK
Background: Preoperative pain and functional status are strong determinants of postsurgical success in total knee arthroplasty. Patients suffering chronic pain from other coexistent musculoskeletal problems may respond differently postoperatively, with potentially poorer outcomes after surgery. The aim of the study was...
0
Race and ethnic variation in proximal femur structure and BMD among older men
Management of Hip Fractures in the Elderly
Femoral neck dimensions and vBMD from QCT were compared among 3,305 black, Asian, Hispanic, and white men >or=65 yr of age. All had similar stature-adjusted mean femoral neck volume, but black and Asian men had thicker cortices and higher trabecular vBMD, which may increase bone strength. INTRODUCTION: Hip fracture rat...
0
Orthopaedic manifestations of mucolipidosis III: an illustrative case
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The musculoskeletal manifestations of mucolipidosis III include short stature, claw hands, carpal tunnel syndrome, and limited joint mobility. This article presents a series of complex orthopaedic problems, including avascular necrosis of the talus, encountered in one such patient whose presentation had initially given...
0
[High dosage vitamin E therapy in patients with activated arthrosis]
Management of Hip Fractures in the Elderly
The known antiphlogistic in vitro effect of vitamin E was tested in a double-blind randomized study in patients with osteoarthritis. Fifty-three in-patients with osteoarthritis of the hip (n = 34) or the knee (n = 19) were treated for 3 weeks with 400 mg vitamin E (d-alpha-tocopherolacetate, V, n = 26) or 50 mg Diclofe...
0
Skeletal manifestations of hydatid disease in Serbia: demographic distribution, site involvement, radiological findings, and complications
MSTS 2022 - Metastatic Disease of the Humerus
Although Serbia is recognized as an endemic country for echinococcosis, no information about precise incidence in humans has been available. The aim of this study was to investigate the skeletal manifestations of hydatid disease in Serbia. This retrospective study was conducted by reviewing the medical database of Inst...
0
Fibroma of the flexor tendon presenting as carpal tunnel syndrome and trigger finger
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
This article examines a rare association of carpal tunnel syndrome and trigger finger produced by a single flexor tendon tumor. Examination and treatment is also discussed
0
Limb salvage and prosthetic joint reconstruction for low-grade and selected high-grade sarcomas of bone after wide resection and replacement by autoclaved [corrected] autogeneic grafts
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Wide resection is an acceptable alternative to amputation for the management of primary sarcomas of the long bones or pelvis. The resected bone can be debrided of gross tumor tissue, autoclaved, and then replaced over intramedullary fixation to reconstruct the limb anatomically. The procedure can be combined with prost...
0
Ipriflavone-treatment of senile osteoporosis: results of a multicenter, double-blind clinical trial of 2 years
Distal Radius Fractures
Eighty�four out of 100 enrolled female patients affected by osteoporosis completed a double�blind, randomized trial, using ipriflavone (IP) in a dose of 3 x 200 mg/day (41 patients) or placebo (P)(43 patients). All patients received 1 g/day oral calcium supplementation. Inclusion criteria were: age over 65 years; a...
0
Osteosarcoma of the jaw: Challenges in the diagnosis and treatment
MSTS 2022 - Metastatic Disease of the Humerus
PURPOSE: Osteosarcomas rarely affect jaw bones. Patients are usually older than those who suffer long bone sarcomas, with a rare incidence of metastasis. This is suggestive of a different pattern of behavior compared with long bone sarcomas. This study aimed to present NCI, Cairo University experience in treating patie...
0
Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells--a preliminary study
MSTS 2018 - Femur Mets and MM
Cathepsins B and L, implicated in the progression of malignant tumors, are regulated by a family of endogenous inhibitors referred to as the cystatins. Cystatin M was identified by differential display as down-regulated gene in metastatic breast cancer cells. However, this finding has yet to be confirmed in clinical br...
0
Functional outcome and quality of life after the surgical treatment for diffuse-type giant-cell tumour around the knee: a retrospective analysis of 30 patients
OAK 3 - Non-arthroplasty tx of OAK
We retrospectively reviewed 30 patients with a diffuse-type giant-cell tumour (Dt-GCT) (previously known as pigmented villonodular synovitis) around the knee in order to assess the influence of the type of surgery on the functional outcome and quality of life (QOL). Between 1980 and 2001, 15 of these tumours had been t...
0
Osteoporosis in the aging male
Management of Hip Fractures in the Elderly
Based on data from the Third National Health and Nutrition Examination Survey, about 1-2 million males in the U.S. have osteoporosis and another 8-13 million have osteopenia, when using male cutoffs for bone mineral density readings. Osteoporosis tends to develop later in life in men, and the incidence of osteoporosis-...
0
Fragility fractures of the ankle in the frail elderly patient: treatment with a long calcaneotalotibial nail
PJI DX Updated Search
Conventional methods of treating ankle fractures in the elderly are associated with high rates of complication. We describe the results of treating these injuries in 48 frail elderly patients with a long calcaneotalotibial nail. The mean age of the group was 82 years (61 to 96) and 41 (85%) were women. All were frail, ...
0
Meniscal repair and replacement
OAK 3 - Non-arthroplasty tx of OAK
Viewed for many years as just vestigial organs, a lack of appreciation of the importance of the menisci led to the widespread practice of total meniscectomy. The realization that removal of these important structures leads to accelerated arthritis took some time. It is now recognized that the menisci play an important ...
0
Patient education before hip or knee arthroplasty lowers length of stay
Surgical Management of Osteoarthritis of the Knee CPG
From April 2006 to May 2007, 261 patients undergoing primary unilateral total hip arthroplasty or total knee arthroplasty were offered voluntary participation in a one-on-one preoperative educational program. Length of stay (LOS) and inpatient data were monitored and recorded, prospectively. Education participants enjo...
1
Lower leg replantation--decision-making, treatment, and long-term results
DoD LSA (Limb Salvage vs Amputation)
OBJECT: The aim of this article is to review the results of replantation at the lower leg after total and subtotal amputation injury. Although subtotal and total lower leg amputations have been successfully replanted in the past, nowadays there is a common opinion that these operations do not justify their efforts, and...
0
Accuracy of synovial fluid analysis compared to histology for the identification of calcium pyrophosphate crystals: an ancillary study of the OMERACT US Working Group - CPPD subgroup
AMP (Acute Meniscal Pathology)
The aim of this study was to evaluate the accuracy of synovial fluid analysis in the identification of calcium pyrophosphate dihydrate crystals compared to microscopic analysis of joint tissues as the reference standard. This is an ancillary study of an international, multicentre cross-sectional study performed by the ...
0
Peroxisome proliferator activated receptor a activation counteracts interleukin 1B induced cytokine production by infrapatellar fat pad
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: The infrapatellar fat pad (IPFP) is located in the knee joint, closely to the cartilage and synovial layer. It contains adipocytes, nerve fibers, macrophages and other immune cells capable of producing cytokines that can influence the osteoarthritis (OA) etiopathogenesis. Peroxisome proliferator activated rece...
0
Fresh Osteochondral Allograft Transplantation for Treatment of Articular Cartilage Defects of the Knee
Osteochondritis Dissecans 2020 Review
Articular cartilage damage of the knee can cause severe morbidity. Owing to its avascular nature, articular cartilage has limited potential for self-healing and increased propensity to progress to osteoarthritis. Treatment of large, full-thickness cartilage defects is still a challenge for orthopaedic surgeons but has ...
0
Isolated dorsal dislocation of the lunate
Distal Radius Fractures
Lunate dislocations are well described in the volar direction as part of the perilunate dislocation, sometimes together with fractures of the other carpal bones or distal radius, as described by the anatomical studies of Mayfield [1]. It is a result of disruption of the complex inter-carpal and radiocarpal ligaments th...
0
Moving social work norms via theater for senior farmers
DoD PRF (Psychosocial RF)
Problem: Senior farmers have a 2.6-fold risk of fatal injury compared to their younger counterparts. Usual educational interventions have resulted in limited success in reducing injury. Method: An innovative strategy, didactic readers theater, was piloted. Farmers' stories provided the foundation for the scripts. The a...
0
Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
OAK 3 - Non-arthroplasty tx of OAK
The investigators propose to prospectively randomize orthopedists, with their patients, to receive (or not) a real�time, web�based system intervention: the OA Care plan. The OA Care plan will include individualized, patient�centric information: (1) trended patient�reported OA pain and function, (2) tailored est...
0
The effectiveness of pulsed electrical stimulation (E-PES) in the management of osteoarthritis of the knee: a protocol for a randomised controlled trial
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Osteoarthritis (OA) of the knee is one of the main causes of musculoskeletal disability in the western world. Current available management options provide symptomatic relief (exercise and self�management, medication and surgery) but do not, in general, address the disease process itself. Moreover, adverse...
0
Arthroscopic Technique for Isolated Posterolateral Rotational Instability of the Knee
AMP (Acute Meniscal Pathology)
Isolated posterolateral corner injury is an uncommon injury that could be a source of unexplained knee pain and dysfunction. Most of these patients present instability caused by concomitant ligament injuries. Numerous studies have shown open approach posterolateral repair or reconstruction surgeries to restore posterol...
0
Treatment of newly diagnosed multiple myeloma
MSTS 2018 - Femur Mets and MM
Multiple myeloma (MM) is the second most common oncohematologic disease. Most patients are older than 65 years at diagnosis, and different therapeutic options are available depending on the age of the patient. For those younger than 65 years, autologous stem cell transplantation is the standard of care, whereas in olde...
0
Dentistry and endocarditis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Bacterial endocarditis (BE), a rare heart infection caused by a bacteremia, has frequently been blamed on but rarely caused by dental procedures. Viridans group streptococci are found abundantly in the mouth and the gingival sulcus but have been surpassed by staphylococci as the leading cause of BE. Antibiotic prophyla...
0
The fine structure of ducts and subareolar ducts in the resting gland of the female breast
Reduction Mammoplasty for Female Breast Hypertrophy
This is the study of the breast tissue of 2 young women subjected to a reduction mastoplasty. In transverse section ducts had longitudinal folds, some of which were solid ridges of cells. Four distinctive cell types were distinguished; epithelial cells, lymphocyte type cells, basal clear cells and myoepithelial cells. ...
0
Geriatric fractures about the hip: divergent patterns in the proximal femur, acetabulum, and pelvis
Hip Fx in the Elderly 2019
Geriatric acetabular, pelvis, and subtrochanteric femur fractures are poorly understood and rapidly growing clinical problems. The purpose of this study was to describe the epidemiologic trends of these injuries as compared with traditional fragility fractures about the hip. From 1993 to 2010, the Nationwide Inpatient ...
0
Population-based prospective study on the incidence of osteoporosis-associated fractures in a German population of 200,413 inhabitants
Distal Radius Fractures
BACKGROUND: A limited body of data is available with regard to the incidence of osteoporotic fractures in Germany. Most of the data published thus far have been derived from hospital records or health insurance settlements. The aim of the present study was to prospectively register four types of fractures in an urban p...
0
Factors predisposing to periprosthetic fracture after hip arthroplasty: a case (n = 31)-control study
Management of Hip Fractures in the Elderly
We compared retrospectively 31 patients with a periprosthetic fracture to 31 patients in a control group. The Finnish Arthroplasty Register was used to count all periprosthetic fractures treated by revision arthroplasty in Finland and in Tampere University Hospital district during the years 1990-1999. We used the date ...
0
Internal fixation for osteochondritis dissecans of the knee
Diagnosis and Treatment of Osteochondritis Dissecans AUC
Eight knees of seven patients with osteochondritis dissecans of the knee underwent internal fixation of the fragments. The affected location was the medial femoral condyle in four knees, the lateral femoral condyle in one knee and the patellar groove in three knees. At the time of surgery, patient age ranged from 13 to...
1
Periprosthetic fractures associated with primary total shoulder arthroplasty and primary humeral head replacement: A thirty-three-year study
Glenohumeral Joint OA
Background: The objective of this study was to assess the frequency of, and risk factors for, periprosthetic fractures during and after shoulder arthroplasty. Methods: All adults treated with a primary total shoulder arthroplasty or humeral head replacement at the Mayo Clinic Medical Center from 1976 to 2008 were ident...
0
Nonsurgical Management of Osteoarthritis Knee Pain in the Older Adult: An Update
AAHKS (4) Acetaminophen
Symptomatic knee osteoarthritis is a common complaint of many elderly patients in primary care offices. For those unable or unwilling to undergo knee replacement, the primary practitionersâ?? understanding of the strengths and weaknesses of the available treatment modalities for pain relief is critical to successful in...
0
Community-based study to estimate prevalence and burden of illness of rheumatic diseases in Cuba: a COPCORD study
HipFx Supplemental Cost Analysis
OBJECTIVE: To estimate the prevalence, burden of illness, and help-seeking behavior of patients with musculoskeletal complaints and provide point prevalence estimates of osteoarthritis, low back pain, fibromyalgia, rheumatoid arthritis, gout, and bone fractures not related to trauma among the adult population in a urba...
0
The effects on surgery stress of preoperative oral carbohydrate intake of knee and hip replacement surgery
Surgical Management of Osteoarthritis of the Knee CPG
In recent years, are developed a special carbohydrate drink that administer before elective surgery for patients cause and cause accelerate gastric emptying, relieve anxiety due to hunger, prevent hypoglycemia and to improve patient comfort. In this study, was investigated the effects of preoperative oral fluid intake ...
0
Preliminary results of Miller-Galante uncemented total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
From July 1984 through February 1986, a total of 46 knees were placed in 42 patients. The average age of all patients was 58 years (range, 32 to 68). Osteoarthritis was the diagnosis in 38 knees, traumatic arthritis in 5, and rheumatoid arthritis in 3. During follow up, averaging 3.6 years (range, 2.0 to 4.5), the tota...
1
A prospective study of antibiotic efficacy in preventing infection in reduction mammaplasty
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: The role of prophylactic antibiotics in reduction mammaplasty remains controversial. However, most surgeons choose to use antibiotics. In addition to cost and potential allergic reactions, unnecessary administration of antibiotics can suppress host natural flora and produce resistant organisms. METHODS: Fif...
0
Can a single dose of 300 mg of pregabalin reach acute antihyperalgesic levels in the central nervous system?
AAHKS (9/10) Regional Nerve Blocks
BACKGROUND AND OBJECTIVES: Central spinal cord sensitization can occur during surgery and may lead to persistent pain after surgery. Pregabalin has been shown to decrease central sensitization in experimental pain paradigms, and so the same antihyperalgesic effect of pregabalin may occur during and immediately after su...
1
Modified hybrid fixator for high-energy Schatzker V and VI tibial plateau fractures
DoD SSI (Surgical Site Infections)
High-energy tibial plateau fractures associated with severe soft tissue injury are difficult to manage. The risk of wound complications following open reduction and internal fixation is notably high owing to extensive soft tissue dissection. Alternatively, application of hybrid external fixator minimizes soft tissue di...
1
LiDCO-based fluid management in patients undergoing hip fracture surgery under spinal anaesthesia: a randomized trial and systematic review
Hip Fx in the Elderly 2019
BACKGROUND: Hip fracture is a condition with high mortality and morbidity in elderly frail patients. Intraoperative fluid optimization may be associated with benefit in this population. We investigated whether intraoperative fluid management using pulse-contour analysis cardiac monitoring, compared with standard care i...
1
Outcomes of tibia shaft fractures caused by low energy gunshot wounds
DoD SSI (Surgical Site Infections)
BACKGROUND: The purpose of this project was to compare the rates of infections, nonunions, malunions, and secondary operations in tibia fractures resultant from low energy GSWs versus those seen in open and closed tibia fractures resultant from blunt trauma. A secondary objective was to assess the utility of using the ...
1
Panniculectomy and the separation-of-parts hernia repair: a solution for the large infraumbilical hernia in the obese patient
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Infraumbilical hernias in the obese are problematic in terms of achieving adequate exposure and eventual wound healing. Simultaneous panniculectomy with separation-of-parts hernia repair is one approach to this reconstructive issue, but the feasibility of such a combination is untested. METHODS: Twenty-four...
0
Magnetic resonance imaging of the knee
AMP (Acute Meniscal Pathology)
Knee pain is frequently seen in patients of all ages, with a wide range of possible aetiologies. Magnetic resonance imaging (MRI) of the knee is a common diagnostic examination performed for detecting and characterising acute and chronic internal derangement injuries of the knee and helps guide patient management. This...
0
The epidemiology of femoral neck fractures in Jerusalem. A prospective study (1967-1971)
Management of Hip Fractures in the Elderly
A prospective study of 570 patients with fracture of the upper end of the femur was carried out between 1967 and 1971 in Jerusalem. Of three distinct ethnic groupings, Western or Ashkenazi females and Eastern or Sephardi males produced the highest incidence of fractured neck of the femur proportional to their makeup in...
0
Obesity has no adverse effect on the outcome of unicompartmental knee replacement at a minimum follow-up of seven years
OAK 3 - Non-arthroplasty tx of OAK
The significance of weight in the indications for unicompartmental knee replacement (UKR) is unclear. Our hypothesis was that weight does not affect the long-term rate of survival of UKRs. We undertook a retrospective study of 212 UKRs at a mean follow-up of 12 years (7 to 22). The patients were distributed according t...
0
Dorsally displaced fractures of the distal radius: a critical appraisal of the DRAFFT (distal radius acute fracture fixation trial) study
Distal Radius Fractures
The results of the DRAFFT (distal radius acute fracture fixation trial) study, which compared volar plating with Kirschner (K-) wire fixation for dorsally displaced fractures of the distal radius, were published in August 2014. The use of K-wires to treat these fractures is now increasing, with a concomitant decline in...
0
[A clinical evaluation of chest wall reconstruction]
Acellular Dermal Matrix
From April 1987 to June 1995, we performed the chest wall reconstruction in 13 cases of 25 ones who had chest wall resection. The clinical records of these 13 patients were reviewed as follows. The histological diagnosis of these cases were direct invasion by primary lung cancer in 13 cases, malignant tumor of the ches...
0
Correlations between serum adipocytokine concentrations, disease stage, radiological status and total body fat content in the patients with primary knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: The study was designed to investigate whether serum concentrations of leptin, resistin and adiponectin in obese and normal-weight patients with primary knee osteoarthritis (OA) correlate with clinical and radiological stages of the disease and percentage of total body fat. METHODS: Seventy-three patients with ...
1
Efficacy of combined ozone and platelet-rich-plasma treatment versus platelet-rich-plasma treatment alone in early stage knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Osteoarthritis (OA) is a chronic disease most often occurring in knee joints, leading to pain of varying severity and deterioration in daily living activities. OBJECTIVE: To compare efficacy of platelet-rich-plasma (PRP) versus PRP in combination with ozone gas injection in patients with early stage knee OA...
0
Association study of MMP8 gene in osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: Osteoarthritis (OA) is a joint disease common in the elderly. There is a prior functional evidence for different matrix metalloproteinases (MMPs), such as MMP8 and MMP9, having a role in the breakdown of cartilage extracellular matrix in OA. Thus, we analyzed whether the common genetic variants of MMP8 and ...
0
Continuous epidural analgesia after total knee arthroplasty: bupivacaine vs ropivacaine [abstract]
Surgical Management of Osteoarthritis of the Knee CPG
European Society of Anaesthesiologists Annual Congress, Amsterdam, The Netherlands, 29 May-1 June 1999
1
Survivorship Analysis and Clinical Outcomes of Transtibial Pullout Repair for Medial Meniscus Posterior Root Tears: A 5- to 10-Year Follow-up Study
AMP (Acute Meniscal Pathology)
PURPOSE: This study investigated the clinical outcomes and mid- to long-term survival rates in patients undergoing transtibial pullout repair of medial meniscus posterior root tears (MMPRTs) after a minimum follow-up of 5 years. METHODS: Between 2005 and 2011, patients with MMPRTs who had been followed for at least 5 y...
0
Enhanced recovery program for hip and knee replacement reduces death rate: A study of 4,500 consecutive primary hip and knee replacements
AAHKS (5) Gabapentinoids
Background and purpose: Multimodal techniques can aid early rehabilitation and discharge of patients following primary joint replacement. We hypothesized that this not only reduces the economic burden of joint replacement by reducing length of stay, but also helps in reduction of early complications. Patients and metho...
1
Ultrasonic investigation of the hip in newborns in the diagnosis of congenital hip dislocation: classification and results of a screening program
Developmental Dysplasia of the Hip CPG
The method of ultrasonic examination of the hip is described, the latest updated Graf classification is explained, and the results of a prospective screening program are described. One thousand four hundred and sixty newborn infants were examined by ultrasound and clinically by independent observers. The distribution o...
0
Incidence and clinical implications of stent fractures of the Xpert self-expanding nitinol stent in infrainguinal arteries
DoD LSA (Limb Salvage vs Amputation)
Background: Different stents in infrainguinal arteries have recently been associated with stent fractures and unfavorable clinical outcome,although data is limited regarding fractures of the Xpert selfexpanding nitinol stent. Thus, purpose of the present investigation was to evaluate its incidence and clinical implicat...
0
Intraarticular fractures of the distal humerus in the adult
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Intraarticular fractures of the distal humerus are notoriously difficult to treat. Three basic treatment methods are available: closed reduction, traction, and open treatment. In the past, functional results with all these methods generally have been poor because of disabling limitations of elbow motion. Thirteen adult...
0
O-linked N-acetylglucosamine (O-GlcNAc) protein modification is increased in the cartilage of patients with knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: There is increasing evidence that the addition of O-linked N-acetylglucosamine (O-GlcNAc) to proteins plays an important role in cell signaling pathways. In chondrocytes, accumulation of O-GlcNAc-modified proteins induces hypertrophic differentiation. Osteoarthritis (OA) is characterized by cartilage degrada...
0
The antioxidant and non-antioxidant contributions of vitamin E in vitamin E blended ultra-high molecular weight polyethylene for total knee replacement
PJI DX Updated Search
Vitamin E (VE) blended ultra-high molecular weight polyethylene (UHMWPE) has been developed in Japan as a material for use in total knee replacement (TKR). Various results have demonstrated that VE blended UHMWPE reduces the incidence of delamination failure and lowers the amount of wear produced during knee simulator ...
0
Haemophilus aphrophilus endocarditis after tongue piercing
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Piercing invades subcutaneous areas and has a high potential for infectious complications. The number of case reports of endocarditis associated with piercing is increasing. We studied a 25-year-old man with a pierced tongue, who arrived at Memorial Health University Medical Center with fever, chills, rigors, and short...
0
Evidence that ORF3 at the Streptococcus parasanguis fimA locus encodes a thiol-specific antioxidant
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Streptococcus parasanguis is a primary colonizer of dental plaque and a major player in subacute bacterial endocarditis. In the present study, the authors report that an ORF (ORF3) located 77 bp downstream of the fimA operon on the S. parasanguis FW213 chromosome complements an Escherichia coli thiol peroxidase (tpx) m...
0
Prosthetic hip joint infection caused by Listeria monocytogenes
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The authors report an unusual case of prosthetic hip joint infection caused by Listeria monocytogenes. The patient, an 87-year-old lady who had undergone a right total hip replacement 10 years previously, presented with pain and restriction of hip motion three weeks after an episode of abdominal pain. Aspiration of the...
0
The segmental tibial fracture
DoD SSI (Surgical Site Infections)
A series of 31 segmental tibial fractures is reported. Eighty-four percent of the patients sustained multiple trauma and 80% of these were open fractures. The series includes treatment with 20 external fixators, seven unreamed intramedullary nails, two casts, and two amputations. Complications included a 48% incidence ...
0
Primary oromandibular reconstruction using free flaps and thorp plates in cancer patients: a 5-year experience
DoD SSI (Surgical Site Infections)
BACKGROUND: Low-profile second-generation THORP titanium plates combined with soft tissues free flaps (forearm or TRAM) can be used for oromandibular reconstruction in patients with SCC in advanced stage (stage III-IV). METHODS: To evaluate long-term stability and possible complications of this reconstructive technique...
0
Fixion nails for humeral fractures
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Humeral fractures in the setting of multi-trauma are usually managed with internal fixation. We prospectively followed nine patients treated with an expandable nail (Fixion, DiscoTech, Medical Technologies, Herzliya, Israel), until union. Internal fixation rapidly stabilises the injured limb, and the lack of distal cro...
0
The clinical and immunological assessment of frozen bone allografts
BMAC (Bone Marrow Aspirate Concentrate)
The clinical results of bone allografts, previously frozen at -70° were reviewed. This revealed satisfactory results in most cases, especially when the grafts were employed in areas of high osteogenic potential, for example with Cloward body infusions (27 fusions/27 cases) or when grafting crush fractures in metaphysic...
1
A Current Review of the Meniscus Imaging: Proposition of a Useful Tool for Its Radiologic Analysis
AMP (Acute Meniscal Pathology)
The main objective of this review was to present a synthesis of the current literature in order to provide a useful tool to clinician in radiologic analysis of the meniscus. All anatomical descriptions were clearly illustrated by MRI, arthroscopy, and/or drawings. The value of standard radiography is extremely limited ...
0
Additional treatment in chronic pain syndrome due to hip and knee arthritis with the selective serotonin reuptake inhibitor fluvoxamine (Fevarin
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: The aim of this study was to investigate the effectiveness and safety of the selective serotonin reuptake inhibitor fluvoxamine (Flevarin) in patients with a chronic pain syndrome due to hip and knee arthritis. METHODS: We prospectively investigated 60 patients in a single�centre double�blind study. The ...
0
Gynaecomastia surgery in the Netherlands: What, why, who, where
Panniculectomy & Abdominoplasty CPG
Gynaecomastia, breast enlargement in men, is common in all age groups. It is operated on by plastic surgeons, general surgeons and paediatric surgeons. It is therefore possible that there is a difference in the populations treated, the indications for surgery and the management used by the different practitioners. We p...
0
Tosic external fixator in the management of proximal tibial fractures in adults
DOD - Acute Comp Syndrome CPG
This retrospective clinical study assessed proximal tibial fractures managed with the Tosic external fixator. Nineteen patients with 21 proximal tibial fractures treated with the Tosic external fixator between July 1997 and October 1998 comprised the study population. Eleven fractures were graded as 41A2, 3 fractures a...
0
Unilateral versus bilateral primary knee osteoarthritis: Relation to the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), C-reactive protein and radiological assessment in Egyptian patients
OAK 3 - Non-arthroplasty tx of OAK
Aim of the work: To study the differences between unilateral and bilateral knee osteoarthritis (KOA) patients in relation to the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), C-reactive protein (CRP) and radiological assessment. Patients and methods: The study included 80 primary KOA patients subg...
0
Current role of emergency ultrasound of the chest
MSTS 2022 - Metastatic Disease of the Humerus
Objective: Chest sonography has gained clinical significance in the diagnosis of various pulmonary, pleural, cardiac, and mediastinal emergency conditions. Therefore, the current role of emergency ultrasound are assessed. Data Source: A systematic literature search of MEDLINE database was performed to identify all stud...
0
Childhood trauma and diurnal cortisol disruption in fibromyalgia syndrome
DoD PRF (Psychosocial RF)
Adults with fibromyalgia syndrome report high rates of childhood trauma. Neuroendocrine abnormalities have also been noted in this population. Exploratory analyses tested relationships between retrospective reports of childhood trauma and diurnal salivary cortisol patterns among 85 women with fibromyalgia. Subjects wit...
1
5 year experience with lower lip cancer
Reconstruction After Skin Cancer
Retrospective study of 189 cases of lower lip cancer treated from 1996-2000 is done. There were 69% males and 31% females. Median age was 66.8 years. 84.4% of patients were with tumors stage I-II. Surgical treatment was performed in 83.6% of patients. In all operated cases was squamous cell carcinoma as verrucous tumor...
0
The association between toe grip strength and osteoarthritis of the knee in Japanese women: A multicenter cross-sectional study
OAK 3 - Non-arthroplasty tx of OAK
We evaluated the relationship between altered foot function and knee osteoarthritis through a specific comparison of toe grip strength in older women with and without knee osteoarthritis.
0
Contemporary bone loss options: Rebuild, reinforce, and augment
PJI DX Updated Search
Bone loss is commonly encountered during revision total knee arthroplasty (TKA). Small defects can be adequately managed with cement filling (with or without screws), modular prosthetic augments, and morselized allograft. For larger defects, cancellous impaction grafting and structural allografts have traditionally bee...
0
Interventions for treating wrist fractures in children
Distal Radius Fractures
Background: Wrist fractures, involving the distal radius, are the most common fractures in children. Most are buckle fractures, which are stable fractures, unlike greenstick and other usually displaced fractures. There is considerable variation in practice, such as the extent of immobilisation for buckle fractures and ...
0
Breast cancer at bone metastatic sites: Recent discoveries and treatment targets
MSTS 2018 - Femur Mets and MM
Breast carcinoma is the most common cancer of women. Bones are often involved with breast carcinoma metastases with the resulting morbidity and reduced quality of life. Breast cancer cells arriving at bone tissues mount supportive microenvironment by recruiting and modulating the activity of several host tissue cell ty...
0
The effect of obesity on mechanical failure after total knee arthroplasty
PJI DX Updated Search
"Increased aseptic tibial failures in patients with a BMI >/=35 and well-aligned total knee arthroplasties" published in The Journal of Arthroplasty on July 2, 2015 draws the conclusion that the risk of revision total knee arthroplasties (TKA) due to aseptic tibial component loosening is two times greater in patients w...
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Manipulation under anesthesia for post traumatic stiff knee-pearls, pitfalls and risk factors for failure
DoD SSI (Surgical Site Infections)
Background Stiffness is common following fractures around knee. Manipulation under anesthesia (MUA) is the initial noninvasive procedure usually performed for such patients. Though MUA has been extensively evaluated for knee arthroplasty, there is paucity of literature regarding its benefits in trauma cases. The purpos...
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Combined Doppler and B-mode sonography in carpal tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
An intraoperatively enlarged engorged median nerve has been described as typical of patients with carpal tunnel syndrome (CTS). Although many studies of CTS have addressed median nerve enlargement, little is known about the usefulness of Doppler methods in detecting median nerve engorgement combined with nerve cross-se...
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Safety and effectiveness profile of raloxifene in long-term, prospective, postmarketing surveillance
Management of Hip Fractures in the Elderly
This large-scale postmarketing surveillance of raloxifene (60 mg/day) was conducted to assess the safety and effectiveness of raloxifene for long-term use in postmenopausal Japanese women with osteoporosis. The baseline examination included 6,967 women (mean age, 70.4 years). Participants completed observation after 6,...
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Complications of Volar Plating of Distal Radius Fractures: A Systematic Review
Distal Radius Fractures
Background In recent years, there has been an increased utilization of volar locking plate fixation of distal radius fractures (DRFs). However, reported long-term complication rates with this technique remain unclear. Purpose The purpose of this systematic review was to investigate the pooled incidence of complications...
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Outcomes of root canal treatment and restoration, implant-supported single crowns, fixed partial dentures, and extraction without replacement: a systematic review
DoD PRF (Psychosocial RF)
STATEMENT OF PROBLEM: Dentists and patients are regularly confronted by a difficult treatment question: should a tooth be saved through root canal treatment and restoration (RCT), be extracted without any tooth replacement, be replaced with a fixed partial denture (FPD) or an implant-supported single crown (ISC)? PURPO...
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Actinobacillus actinomycetemcomitans isolated from a case of cutaneous botryomycosis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Cutaneous botryomycosis is an uncommon chronic suppurative bacterial skin infection that can mimic a fungal infection both clinically and histopathologically. Causative bacteria, most commonly Staphylococcus aureus, aggregate to form characteristic granules. We report the case of a 52-year-old black man who developed c...
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Composite grafting of the maxillary sinus for placement of endosteal implants. A preliminary report of 48 patients
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The maxillary sinuses in 48 patients were grafted with dense, non-resorbable hydroxylapatite (HA) particles combined with autologous, cancellous bone. After 3 months of healing, HA-coated titanium endosteal implants were placed in the maxilla, and following an additional 3-5 month healing period, the dentitions were re...
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Perioperative infection rate in patients with osteosarcomas treated with resection and prosthetic reconstruction
PJI DX Updated Search
BACKGROUND: The incidence of perioperative infection after segmental tumor endoprosthetic replacement in previous reports varies from a high of 7.4% to a low of 2.6%. Appropriate antibiotic use for this group is unknown and controversial, whereas the relationship of antibiotic use and perioperative infection is unclear...
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Immediate effects of foot orthoses on pain during functional tasks in people with patellofemoral osteoarthritis: A cross-over, proof-of-concept study
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: The purpose of the study was to determine whether prefabricated foot orthoses immediately reduce pain during functional tasks in people with patellofemoral osteoarthritis, compared to flat insoles and shoes alone. METHODS: Eighteen people with predominant lateral patellofemoral osteoarthritis (nine women; m...
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Correlation of neoplasms with incidence and localization of skeletal metastases: An analysis of 1,355 diphosphonate bone scans
MSTS 2018 - Femur Mets and MM
A total of 1,355 patients from clinical trails with the 99mTc-labeled bone agent, Osteoscan (99mTc-Sn -EHDP), has shown a higher incidence of skeletal abnormalities than previously reported. Overall in this study, 60% of bone scans were abnormal in patients with nonosseous neoplasms. Carcinoma of breast, lung, and pros...
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Effects of increased intra-abdominal pressure in severe obesity
DoD - ACS - Interrater Reliability
This article gives an overview, citing animal and clinical studies, of the effects of increased intra-abdominal pressure (IAP) in severe obesity. Animal studies demonstrate that increased IAP increases pleural pressure, cardiac filling pressures, femoral venous pressure, renal venous pressure, systemic blood pressure, ...
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Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression
Panniculectomy & Abdominoplasty CPG
AIMS/HYPOTHESIS: Autotaxin is a lysophospholipase D that is secreted by adipocytes and whose expression is substantially up-regulated in obese, diabetic db/db mice. The aim of the present study was to depict the physiopathological and cellular mechanisms involved in regulation of adipocyte autotaxin expression. METHODS...
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Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma
MSTS 2018 - Femur Mets and MM
Multiple myeloma (MM) is incurable, mainly because of cell adhesion-mediated drug resistance (CAM-DR). In this study, we performed functional screening using short hairpin RNA (shRNA) to define the molecule(s) responsible for CAM-DR of MM. Using four bona fide myeloma cell lines (KHM-1B, KMS12-BM, RPMI8226 and U266) an...
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Panobinostat, a pan-histone deacetylase inhibitor: Rationale for and application to treatment of multiple myeloma
MSTS 2018 - Femur Mets and MM
Histone deacetylase inhibitors (HDACis) have emerged as novel therapeutic agents for cancer. Currently, four HDACis are approved by the Food and Drug Administration (FDA) to treat various hematologic malignancies. Panobinostat (LBH-589, trade name Farydak®, developed and marketed by Novartis) is a potent pan-HDACi wit...
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18F-FDG PET/CT for the prediction and detection of local recurrence after radiofrequency ablation of malignant lung lesions
MSTS AUC - Based on ACR Lit Review
UNLABELLED: The utility of (18)F-FDG PET/CT for response assessment in malignant lung tumors treated with radiofrequency ablation (RFA) and for the detection and prediction of local recurrence was investigated. METHODS: Between December 17, 2003, and April 9, 2008, 68 consecutive patients (mean age, 68 y) with 94 pulmo...
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Perioperative complication rate of one-stage bilateral total hip arthroplasty using the direct anterior approach
Hip Fx in the Elderly 2019
BACKGROUND: To date, details of the surgical and clinical outcomes of one-stage bilateral total hip arthroplasty using the direct anterior approach have not been widely available. The purpose of this study was to report the perioperative blood management and investigate the perioperative complication rate of one-stage ...
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Skp2 protein expression in soft tissue sarcomas
MSTS 2022 - Metastatic Disease of the Humerus
Background: p45 S phase kinase-assotiated protein-2 (p45skp2), a member of the F-box family of proteins, is an important component of the Skp 1-Cullin-F-box protein (SCF) ubiquitin-ligase complex (SCFskp2). The latter has been implicated in the ubiquitination and degradation of p27 kip1 (p27) and G1-S cell cycle progre...
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Cementless femoral revision arthroplasty. 2- to 5-year results with a modular titanium alloy stem
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Seventy-five consecutive cementless femoral revision arthroplasties were performed, using a modular titanium alloy stem (S-ROM, Joint Medical Products, Stamford, CT). Sixty-six hips were available for complete follow-up evaluation at 2 to 5 years (average, 3.4 years). Independent clinical analysis compared pre- with po...
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Limb Salvage After Failed Initial Operative Management of Bimalleolar Ankle Fractures in Diabetic Neuropathy
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Ankle fractures in patients with diabetes mellitus (DM) can be difficult to manage, especially in the presence of peripheral neuropathy. In patients who fail initial operative management, attempts at limb salvage can be challenging, and no clear treatment algorithm exists. This study examined outcomes of di...