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0 | Complex Primary Total Knee Arthroplasty: Long-Term Outcomes | PJI DX Updated Search | BACKGROUND: Total knee arthroplasty in patients with severe preoperative deformity, ligamentous instability, and/or marked bone loss occasionally requires a varus and valgus constrained or rotating-hinge design prosthesis. The purpose of this study was to compare patient populations that underwent primary total knee ar... |
0 | Norepinephrine turnover in brown and white adipose tissue after partial lipectomy | Panniculectomy & Abdominoplasty CPG | Total body fat is restored after the surgical removal (i.e., partial lipectomy) of white adipose tissue (WAT), and this is accomplished via increases in the mass of nonexcised WAT pads. The underlying mechanism for this apparent regulation of total body fat is unknown. One possibility is via the sympathetic nervous sys... |
0 | Camalexin-induced apoptosis in prostate cancer cells involves alterations of expression and activity of lysosomal protease cathepsin D | MSTS 2018 - Femur Mets and MM | Camalexin, the phytoalexin produced in the model plant Arabidopsis thaliana, possesses antiproliferative and cancer chemopreventive effects. We have demonstrated that the cytostatic/cytotoxic effects of camalexin on several prostate cancer (PCa) cells are due to oxidative stress. Lysosomes are vulnerable organelles to ... |
0 | Treatment of extended osteochondral lesions of the talus with a free vascularised bone graft from the medial condyle of the femur | Glenohumeral Joint OA | Large osteochondral lesions (OCLs) of the shoulder of the talus cannot always be treated by traditional osteochondral autograft techniques because of their size, articular geometry and loss of an articular buttress. We hypothesised that they could be treated by transplantation of a vascularised corticoperiosteal graft ... |
0 | Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts.
METHODS: We utilised conditioned media cultures, Western blot analysis and immunocytochemistry to investigate the differential effe... |
0 | Standard Anatomical and Visual Space for the Mouse Retina: Computational Reconstruction and Transformation of Flattened Retinae with the Retistruct Package | Upper Eyelid and Brow Surgery | The concept of topographic mapping is central to the understanding of the visual system at many levels, from the developmental to the computational. It is important to be able to relate different coordinate systems, e.g. maps of the visual field and maps of the retina. Retinal maps are frequently based on flat-mount pr... |
0 | Use magnetic resonance imaging to assess articular cartilage | PJI DX Updated Search | Magnetic resonance imaging (MRI) enables a noninvasive, three-dimensional assessment of the entire joint, simultaneously allowing the direct visualization of articular cartilage. Thus, MRI has become the imaging modality of choice in both clinical and research settings of musculoskeletal diseases, particular for osteoa... |
1 | Factors affecting long-term results after arthroscopic partial meniscectomy | Anterior Cruciate Ligament Injuries CPG | The purpose of this study was to determine functional and radiographic changes on long-term followup of knees with isolated meniscal tears. Sixty-seven patients were evaluated retrospectively with an average of 12.2 years' followup using the scale of Tapper and Hoover. The criteria for the radiographic results were the... |
0 | A randomized, controlled, prospective study evaluating the effect of patellar eversion on functional outcomes in primary total knee arthroplasty | PJI DX Updated Search | Background: Patellar mobilization technique during total knee arthroplasty has been debated, with some suggesting that lateral retraction, rather than eversion, of the patella may be beneficial. We hypothesized that patients with knees surgically exposed using patellar lateral retraction would have comparable outcomes ... |
0 | Risk factors of recurrent hamstring injuries: a systematic review | DoD PRF (Psychosocial RF) | Although recurrent hamstring injury is a frequent problem with a significant impact on athletes, data on factors determining the risk for a recurrent hamstring injury are scarce. To systematically review the literature and provide an overview of risk factors for re-injury of acute hamstring muscle injuries. Prospective... |
1 | Magnetic resonance imaging versus arthroscopy in the diagnosis of knee pathology, concentrating on meniscal lesions and ACL tears: a systematic review | AMP (Acute Meniscal Pathology) | PURPOSE: Magnetic resonance imaging (MRI) is of great aid in the diagnosis of knee lesions. Most diagnostic studies comparing MRI and arthroscopy have shown good diagnostic performance in detecting lesions of the menisci and cruciate ligaments. Nevertheless, arthroscopy has remained the reference standard for the diagn... |
0 | Use of an Ultrasound-Based Navigation System for an Accurate Acetabular Positioning in Total Hip Arthroplasty. A Prospective, Randomized, Controlled Study | Management of Hip Fractures in the Elderly | The purpose of this study was to compare an ultrasound-based navigation system with an imageless navigation system with surface registration in the postoperative acetabular cup position. A prospective randomized controlled study of 2 groups of 40 patients each was performed. In the first group, cup positioning was assi... |
0 | Management of traumatic meniscal tear and degenerative meniscal lesions. Save the meniscus | OAK 3 - Non-arthroplasty tx of OAK | Meniscectomy remains one of the most frequent orthopedic procedures, despite meniscal sparing having been advocated for several decades now. Incidence is excessive in the light of scientifically robust studies demonstrating the interest of meniscal repair or of nonoperative treatment for traumatic tear and of nonoperat... |
0 | Emerging anabolic treatments for osteoporosis | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Therapy for osteoporosis is principally centered on the use of agents that block bone resorption and supplementation with vitamin D and calcium. Although these drugs are effective in reducing the risk of subsequent fractures, and modestly increasing bone density, most patients being treated for osteoporosis still have ... |
1 | The health burden and costs of incident fractures attributable to osteoporosis from 2010 to 2050 in Germany--a demographic simulation model | HipFx Supplemental Cost Analysis | To predict the burden of incident osteoporosis attributable fractures (OAF) in Germany, an economic simulation model was built. The burden of OAF will sharply increase until 2050. Future demand for hospital and long-term care can be expected to substantially rise and should be considered in future healthcare planning. ... |
0 | Shared decision making, preoperative expectations, and postoperative reality: differences in physician and patient predictions and ratings of knee surgery outcomes | AMP (Acute Meniscal Pathology) | PURPOSE: The present study was performed to determine the extent to which physicians and patients rate preoperative and postoperative knee pain and function differently, and to determine whether physicians or patients more accurately predict postoperative knee pain and function.
TYPE OF STUDY: Longitudinal, prospective... |
1 | Strength training alone, exercise therapy alone, and exercise therapy with passive manual mobilisation each reduce pain and disability in people with knee osteoarthritis : a systematic review | Non-Arthroplasty Treatment of Osteoarthritis of the Knee AUC | QUESTION: What are the effects of strength training alone, exercise therapy alone, and exercise with additional passive manual mobilisation on pain and function in people with knee osteoarthritis compared to control? What are the effects of these interventions relative to each other? DESIGN: A meta-analysis of randomis... |
0 | "Not always a straight path": patients' perspectives following anterior cruciate ligament rupture and reconstruction | DoD PRF (Psychosocial RF) | PURPOSE: To explore patients' perspectives following anterior cruciate ligament rupture and subsequent reconstructive surgery.
METHODS: A qualitative study design was employed, using validated questionnaires, interviews and general inductive methodology. Semi-structured interviews were conducted with five men and four ... |
0 | Opioid Prescribing Habits for Common Arthroscopic Procedures in Opioid Naïve Patients | AMP (Acute Meniscal Pathology) | Background: With the opioid epidemic and the increasing number of opioid-related deaths, there is growing awareness in the medical community regarding the dangers of opioid overprescription. As a result, there is a willingness among physicians to abandon old norms and adopt new data-driven prescribing practices. Purpos... |
1 | Incidence of complex regional pain syndrome type I after fractures of the distal radius | DoD PRF (Psychosocial RF) | Aim of this study was to analyse the incidence CRPS-I after a fracture of the distal radius and to analyse risk factors. Patients who visited the Emergency Unit of the University Hospital, with a fracture of distal radius were asked to participate. As risk factors for CRPS-I, number of repositions (with or without loca... |
0 | The effect of a stem on the tibial component of knee arthroplasty. A roentgen stereophotogrammetric study of uncemented tibial components in the Freeman-Samuelson knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | We studied the effect of a metal tray with an intramedullary stem on the micromotion of the tibial component in total knee arthroplasty. Of 32 uncemented Freeman-Samuelson knee arthroplasties performed in London and Gothenburg, nine had a metal backing and stem added to the tibial component. Micromotion of the tibial c... |
0 | Correlation between complication rate and tissue resection volume in inferior pedicle reduction mammaplasty: a retrospective study | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: The inferior pedicle technique is the most common breast reduction procedure performed in the United States today. Traditionally, it has been recommended that pedicle techniques not be used for large volume breast reduction (>1000 gm/breast), as the complication rate may be unacceptably high.
OBJECTIVE: We ... |
0 | Intermittent negative pressure wound therapy with instillation for the treatment of persistent periprosthetic hip infections: a report of two cases | PJI DX Updated Search | Intermittent negative pressure wound therapy with instillation (NPWTi) is starting to be used successfully to treat early periprosthetic infections of endoprostheses. However, few articles have reported the outcome of treatment with intermittent NPWTi for late persistent periprosthetic infections of the hip. In this st... |
1 | Cosmesis with bilateral mammoreduction for conservative breast cancer treatment | Reduction Mammoplasty for Female Breast Hypertrophy | Over 7 years, 57 women with breast cancer underwent lumpectomy and bilateral mammoreduction. Physical complaints about large or lax breast shape were the predominate rationale. Two patients were immediately lost to follow-up, 55 patients remained and were followed every 3 months for an average of 1.6 years. This is the... |
0 | Revisiting Triple Antibiotic Irrigation of Breast Implant Pockets: A Placebo-controlled Single Practice Cohort Study | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Capsular contracture is the most common complication following primary augmentation mammoplasty. It remains poorly understood but is attributed to subclinical infection, immunologic response to breast implants, and chronic inflammatory changes caused by the presence of the implants. The infectious theory of... |
0 | Factors affecting the achievement of Japanese-style deep knee flexion after total knee arthroplasty using posterior-stabilized prosthesis with high-flex knee design | OAK 3 - Non-arthroplasty tx of OAK | Background: Achievement of very deep knee flexion after total knee arthroplasty (TKA) can play a critical role in the satisfaction of patients who demand a floor-sitting lifestyle and engage in high-flexion daily activities (e.g., seiza-sitting). Seiza-sitting is characterized by the knees flexed >145º and feet turned... |
0 | A self-compensated spin-locking scheme for quantitative R1? dispersion MR imaging in ordered tissues | AMP (Acute Meniscal Pathology) | Purpose: To propose a self-compensated spin-locking (SL) method for quantitative R1? dispersion imaging in ordered tissues. Methods: Two pairs of antiphase rotary-echo SL pulses were proposed in a new scheme with each pairs sandwiching one refocusing RF pulse. This proposed SL method was evaluated by Bloch simulations ... |
0 | The problem of post-traumatic varization of the distal end of the humerus remaining after the recovery of a supracondylar fracture | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | We aimed to determine whether the distal end of the humerus had the capacity of spontaneous realignment of the remaining deformity following an inadequate reposition of the supracondylar fracture. The results in 56 children with a supracondylar humerus fracture were analysed. In 45 patients (80%), manual repositioning ... |
0 | Comparison of a novel muscle training device with conventional rehabilitation training in motor dysfunction of lower limb patients: A pilot study | Hip Fx in the Elderly 2019 | Background: Postoperative functional training for fracture or osteoarthritis is mainly focused on functional self-exercise, which aims to recover the function of the lower limbs. Purpose: To compare the function and life quality recovery in patients with fracture or arthritis treated with novel muscle training device (... |
0 | Bone regeneration therapy of atraumatic necrosis of femoral head | BMAC (Bone Marrow Aspirate Concentrate) | Femoral head necrosis is a mobility disorder and till now no satisfactory solution has been reported. The principal contributing factor in the pathogenesis of the disease is insufficient blood supply to the femoral head resulting in necrosis of the femoral head. Various preventive measures required to treat femoral hea... |
0 | Pneumococcal meningitis and etanercept-chance or association? | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Rheumatoid arthritis is a severe deforming chronic disease which has major implications for mortality and quality of life. Agents with anti-tumour necrosis factor alpha (TNF(alpha)) activity are a new modality of therapy, which can significantly reduce the acute inflammation in this condition. However, TNF(alpha) is a ... |
0 | Consensus document on controversial issues in the diagnosis and treatment of prosthetic joint infections | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | BACKGROUND: Joint replacement surgery has been on the increase in recent decades and prosthesis infection remains the most critical complication. Many aspects of the primary prevention and clinical management of such prosthesis infections still need to be clarified. CONTROVERSIAL ISSUES: The aim of this GISIG (Gruppo I... |
0 | Distal radius fracture malunion: Importance of managing injuries of the distal radio-ulnar joint | Distal Radius Fractures | BACKGROUND: Distal radius malunion is a major complication of distal radius fractures, reported in 0 to 33% of cases. Corrective osteotomy to restore normal anatomy usually provides improved function and significant pain relief. We report the outcomes in a case-series with special attention to the potential influence o... |
0 | Resilience and quality of life: An investigation of Kumpferâ??s resilience model with persons with spinal cord injuries | DoD PRF (Psychosocial RF) | The construct of resilience is key to understanding adaptation to disability from a strengths-based perspective. The objective of this study was to examine the impact of factors identified in Kumpferâ??s resilience model on quality of life (QOL) outcomes for adults with spinal cord injury (SCI), specifically taking int... |
0 | The impact of glucocorticoid therapy on trabecular bone score in older women | Pediatric Supracondylar Humerus Fracture 2020 Review | Summary: We propose that trabecular bone score could be a useful tool for the study of glucocorticoid-associated bone effects. Trabecular bone score alone and lumbar spine bone mineral density (BMD) used in combination with trabecular bone score, but not lumbar spine BMD alone was able to discriminate between glucocort... |
0 | Risedronate Rapidly Reduces the Risk for Nonvertebral Fractures in Women with Postmenopausal Osteoporosis | Management of Hip Fractures in the Elderly | Prevention of nonvertebral fractures, which account for a substantial proportion of osteoporotic fractures, is an important goal of osteoporosis treatment. Risedronate, a pyridinyl bisphosphonate, significantly reduces clinical vertebral fracture incidence within 6 months. To determine the effect of risedronate on oste... |
0 | Antibiotic Spacer Arthroplasty for Revision MTP Arthrodesis: A Novel Means to Build the Implant: A Case Report | PJI DX Updated Search | Metatarsophalangeal (MTP) joint osteoarthritis (OA), also known as hallux rigidus (HR), is the most common degenerative arthropathy of the foot and is often the result of trauma. There are multiple methods of addressing the patient's pain and limited function. Arthrodesis is the gold standard to manage severe MTP arthr... |
1 | Early complications after high tibial osteotomy: a comparison of two techniques | Non-Arthroplasty Treatment of Osteoarthritis of the Knee AUC | This prospective cohort study compared opening wedge high tibial osteotomy with use of the Puddu plate and the Vitoss synthetic cancellous bone versus closing wedge high tibial osteotomy with use of the AO/ASIF L-plate, focusing on complications (nonunions, infections, loss of correction, reoperations) and patient sati... |
0 | Preoperative chlorhexidine preparation and the incidence of surgical site infections after hip arthroplasty | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | The purpose of this study was to evaluate effectiveness of an advance, at-home chlorhexidine-impregnated skin preparation cloth in decreasing the incidence of deep periprosthetic hip arthroplasty infections. Arthroplasty surgeons at the senior author's institution provided their patients with chlorhexidine-impregnated ... |
0 | Outcome of Islanded Gastrocnemius Musculocutaneous Flap in Orthopaedic Practice | DoD SSI (Surgical Site Infections) | <b>Introduction:</b> Large wounds in the leg require combination of local flaps or free flap for wound coverage. Gastrocnemius musculocutaneous flap (GMCF) allows a large wound to be covered by a single local flap. However, the conventional GMCF is often associated with donor site morbidity where the exposed soleus rap... |
0 | Biomechanical Response to Osteoarthritis Pain Treatment May Impair Long-Term Efficacy | OAK 3 - Non-arthroplasty tx of OAK | Pain has an important physiologic role and acts with or stimulates motor system adaptations to protect tissue from threats of damage. Although clinically beneficial, removing the protective pain response may have negative consequence in osteoarthritis, a mechanically mediated disease. We hypothesize motor system adapta... |
0 | Local Treatment with Adjuvant Therapy for Central Atypical Cartilaginous Tumors in the Long Bones: Analysis of Outcome and Complications in One Hundred and Eight Patients with a Minimum Follow-up of Two Years | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND: A central atypical cartilaginous tumor (ACT)--formerly known as chondrosarcoma grade 1 (CS1)--is a tumor of intermediate-type malignancy, often treated with surgery. The extent of surgery remains controversial, as some advocate resection and others favor local treatment by curettage. Because of the low prev... |
0 | Generating hypotheses about care needs of high utilizers: lessons from patient interviews | DoD PRF (Psychosocial RF) | Informed by a largely secondary and quantitative literature, efforts to improve care and outcomes for complex patients with high levels of emergency and hospital-based health care utilization have offered mixed results. This qualitative study identifies psychosocial factors and life experiences described by these patie... |
1 | Hip muscle strength and protection against structural worsening and poor function and disability outcomes in knee osteoarthritis | OAK 3 - Non-arthroplasty tx of OAK | Objective: Examine associations of hip abductor strength with (1) cartilage damage worsening in the tibiofemoral and patellofemoral compartments 2 years later, and (2) poor function and disability outcomes 5 years later. Methods: Participants had knee osteoarthritis (K/L â?¥ 2) in at least one knee. Hip abductor streng... |
0 | Trochanteric bone grafts in foot and ankle surgery | Management of Hip Fractures in the Elderly | Eighty-five patients who underwent trochanteric bone graft harvest in association with foot and ankle surgery were studied retrospectively by patient questionnaire. The average follow-up was 49 months (range, 14-101 months). Ninety-five percent of the patients expressed satisfaction with the procedure, in that they wou... |
0 | Hope versus hype: what can additive manufacturing realistically offer trauma and orthopedic surgery? | PJI DX Updated Search | Additive manufacturing (AM) is a broad term encompassing 3D printing and several other varieties of material processing, which involve computer-directed layer-by-layer synthesis of materials. As the popularity of AM increases, so to do expectations of the medical therapies this process may offer. Clinical requirements ... |
0 | The functional outcome of lower-extremity fractures with vascular injury | DoD SSI (Surgical Site Infections) | Salvage of lower-extremity Gustilo type IIIC fractures is difficult, time-consuming for the patients and physicians, and not universally successful because of poor functional outcomes. Even if successful with limb salvage, the functional result may be unsatisfactory because of mutilating injuries to muscle and nerve, b... |
0 | Mapping tibiofemoral gonarthrosis: an MRI analysis of non-traumatic knee cartilage defects | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Arthroscopy is "the gold standard" for the diagnosis of knee cartilage lesions. However, it is invasive and expensive, and displays all the potential complications of an open surgical procedure. Ultra-high-field MRI now offers good opportunities for the indirect assessment of the integrity and structural cha... |
1 | Pulseless arm in association with totally displaced supracondylar fracture | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Seven children (3-10 years of age) were treated for a type III supracondylar fracture of the humerus. All fractures were reduced and pinned. Closed reduction was performed in four patients; three required open reduction. Before reduction six of the seven patients did not have a distal palpable pulse in the involved for... |
0 | The initial effects of knee joint mobilization on osteoarthritic hyperalgesia | OAK 3 - Non-arthroplasty tx of OAK | Physiotherapists often employ lower limb joint mobilization to reduce pain and increase function. However, there is little experimental data confirming its efficacy. The purpose of this study was to investigate the initial effects of accessory knee joint mobilization on measures of pain and function in individuals with... |
0 | Repair of distal biceps tendon rupture using a suture anchor: Description of a new endoscopic procedure | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Background: Repair of a distal biceps tendon rupture is a challenging procedure and, to date, there is no consensus as to which technique should be used because of the specific complications reported for each. Purpose: A new endoscopic technique is described that uses a suture anchor to repair distal biceps tendon rupt... |
0 | Autologous platelet gel for tissue regeneration in degenerative disorders of the knee | AMP (Acute Meniscal Pathology) | Background. The refinement of the use of platelet-derived growth factors that has occurred over the last decade has led to a broadening of the fields of use, in particular for new treatments in orthopaedics aimed at improving tissue regeneration. Materials and methods. Twenty-seven patients, aged between 18 and 81 year... |
0 | Calcium phosphate bone cement for treatment of distal radius fractures: a preliminary report | Distal Radius Fractures | Distal radius fractures in osteoporotic patients are often complicated with a residual deformity and a subsequent stiff and painful wrist. The aim of this study was to evaluate the usefulness of calcium phosphate bone cement (CPC95) in the treatment of these fractures. Seven Colles type fractures in seven patients (all... |
1 | Medium-long-term radiographic and clinical outcomes after surgical treatment of intra-articular tibial pilon fractures by three different techniques | DoD SSI (Surgical Site Infections) | Introduction. The goal of this retrospective, observational, case series study was to evaluate the medium-long-term clinical and radiographic results of the three most common surgical osteosynthesis techniques used for the treatment of articular tibial pilon fractures: ORIF, MIPO, and EF. Materials and Methods. A conse... |
0 | A Mycobacterium malmoense infection of the hand presenting as carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | We report an atypical tuberculous infection by Mycobacterium Malmoense of the synovium of the flexor tendons at the wrist presenting as carpal tunnel syndrome. This is the first time this organism has been described in a site other than the lungs or the cervical lymph nodes |
0 | Diffuse and localised visual field defects to automated perimetry in primary open angle glaucoma | Upper Eyelid and Brow Surgery | The occurrence of generalised or diffuse visual field depression in primary open angle glaucoma (POAG), in contrast to the presence of characteristic localised defects, is controversial. The frequency of diffuse visual field loss to automated static perimetry in the early stages of POAG was determined and compared with... |
1 | Preoperative gabapentin in patients undergoing primary total knee arthroplasty | AAHKS (5) Gabapentinoids | Background: Patients undergoing total knee arthroplasty usually receive a multimodal analgesic regimen including peripheral nerve blockade, but may still experience significant pain. This study examined whether preoperative gabapentin decreases acute postoperative pain and opioid consumption in this setting. Methods: R... |
0 | Deep vein thrombosis after elective knee surgery. An incidence study in 312 patients | AMP (Acute Meniscal Pathology) | The incidence of venous thromboembolism after elective knee surgery has previously been studied almost exclusively in patients receiving total knee replacements, in whom the risk of a deep vein thrombosis is approximately 60%. We report the results of ipsilateral ascending venography in 312 patients undergoing a wide v... |
0 | Predicting the risk of deep infections following total knee replacement: A pragmatic, prognostic risk score | Surgical Management of Osteoarthritis of the Knee CPG | Surgeons and patients need a tool to predict deep infections following total knee replacement. We developed a pragmatic, points-based risk score to predict knee deep infections for clinical decision making. Using a large health care organization's joint replacement registry, we identified deep infections associated wit... |
0 | Breast dose reduction for chest CT by modifying the scanning parameters based on the pre-scan size-specific dose estimate (SSDE) | Reduction Mammoplasty for Female Breast Hypertrophy | Objective: To investigate the usefulness of modifying scanning parameters based on the size-specific dose estimate (SSDE) for a breast-dose reduction for chest CT. Materials and methods: We scanned 26 women with a fixed volume CT dose index (CTDIvol) (15Â mGy) and another 26 with a fixed SSDE (15Â mGy) protocol (protoc... |
0 | Imaging modalities for identifying the origin of regional musculoskeletal pain | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Regional musculoskeletal pain is one of the most common complaints in daily rheumatological practice. Conventional radiology remains the cornerstone of diagnostic imaging in these patients despite the advent of new, fascinating imaging techniques. Ultrasonography may have a relevant impact on final diagnosis or therape... |
1 | Fixator-assisted Technique Enables Less Invasive Plate Osteosynthesis in Medial Opening-wedge High Tibial Osteotomy: A Novel Technique | DoD SSI (Surgical Site Infections) | BACKGROUND: Opening-wedge high tibial osteotomy is a well-established procedure in the management of medial osteoarthritis of the knee and correction of proximal tibia vara. Recently, surgical approaches using less invasive plate osteosynthesis have been used with the goal of minimizing complications from more extensiv... |
0 | Racial and ethnic disparities in hip and knee joint replacement: a review of research in the Veterans Affairs Health Care System | Surgical Management of Osteoarthritis of the Knee CPG | Elective total joint arthroplasty is an effective treatment option for end-stage osteoarthritis of the hip and knee. The demand for arthroplasty is anticipated to increase as the proportion of older patients with hip and knee osteoarthritis continues to rise in the United States and worldwide. Studies have documented m... |
0 | Analysis of polymorphisms in the MATN3 and DOT1L Genes and CTX-II urinary levels in patients with knee osteoarthritis in a northeast mexican-mestizo population | OAK 3 - Non-arthroplasty tx of OAK | Aims: To investigate the possible roles of the single nucleotide polymorphisms (SNPs) MATN3 (rs77245812) and DOT1L (rs12982744) with susceptibility to knee osteoarthritis (KOA) among mestizos from the northeast region of Mexico. In addition, we analyzed the relationship of their urinary levels of carboxy terminal telop... |
0 | Bilateral carpal tunnel syndrome and bilateral cubital tunnel syndrome in a patient with cervical disc herniations | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Entrapment neuropathies, cervical spondylosis and disc herniations are all well known, common neuromuscular pathologies. A complicated clinical presentation may emerge incase the forementioned problems overlap. We present a similar patient with bilateral carpal tunnel syndrome, bilateral cubital tunnel syndrome and cer... |
0 | Regional anesthesia for knee surgery | Surgical Management of Osteoarthritis of the Knee CPG | Knee surgery may be performed under general anesthesia, preferably, however, under regional anesthesia because of the profound preemptive analgesic effect that is provided by regional anesthetic techniques. Both centroneuraxis (spinal, epidural) as well as peripheral nerve blocks may be used for knee surgery. Although ... |
1 | Endoscopic carpal tunnel release--current status | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Endoscopic carpal tunnel release is one of the most controversial topics in hand surgery today. Many surgeons have reservations in doing carpal tunnel release endoscopically because its merits and demerits have not been clearly defined. This article describes the various techniques now available to perform endoscopic c... |
1 | Perineuronal morphine: a comparison with epidural morphine | Surgical Management of Osteoarthritis of the Knee CPG | In a double-blind, randomised controlled cross-over study the effects of perineuronal (perifemoral) injections of morphine were compared with epidural injections with the same amount of morphine in patients after knee surgery. Better pain scores were achieved during treatment with epidural morphine. We have not been ab... |
0 | Operative treatment of displaced fractures of the acetabulum. A meta-analysis | DoD SSI (Surgical Site Infections) | Over the past 40 years, the management of displaced fractures of the acetabulum has changed from conservative to operative. We have undertaken a meta-analysis to evaluate the classification, the incidence of complications and the functional outcome of patients who had undergone operative treatment of such injuries. We ... |
0 | Calcium, magnesium, zinc and lead concentrations in the structures forming knee joint in patients with osteoarthritis | AMP (Acute Meniscal Pathology) | The aim of the study was to investigate the relationships between the concentrations of calcium (Ca), magnesium (Mg), zinc (Zn), and lead (Pb) in cartilage, anterior cruciate ligament, and meniscus samples obtained following knee joint surgery in patients with osteoarthritis in northwestern Poland. Furthermore, we exam... |
1 | Radiographic Study of Humeral Stem in Shoulder Arthroplasty After Lesser Tuberosity Osteotomy or Subscapularis Tenotomy | Glenohumeral Joint OA | Lesser tuberosity osteotomy (LTO) and subscapularis tenotomy (ST) are used for takedown of the subscapularis during shoulder arthroplasty. LTO offers the theoretical but unproven benefit of improved healing and function of the subscapularis. However, humeral stem subsidence and loosening may be greater when osteotomy i... |
0 | First Case of Lyme Arthritis Involving a Prosthetic Knee Joint | PJI DX Updated Search | Borrelia burgdorferi sensu stricto is the most common tick-borne illness in the United States. Arthritis is usually a mani-festation of late dis-ease but has not been associated with cases of periprosthetic joint infections. We report on a patient who was first diagnosed with periprosthetic joint infection and subseque... |
0 | Fungal periprosthetic joint infection of the hip: a systematic review | PJI DX Updated Search | Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management of fungal PJI of the... |
0 | Hidradenitis suppurativa | Reconstruction After Skin Cancer | BACKGROUND: Hidradenitis suppurativa (HS) is a recurrent, suppurative disease manifested by abscesses, fistulas, and scarring. METHODS: We reviewed the literature to identify reliable information regarding epidemiology, pathogenesis, clinical manifestations, evaluation and differential diagnosis, treatment, complicatio... |
1 | Safety and efficacy of US-approved viscosupplements for knee osteoarthritis: a systematic review and meta-analysis of randomized, saline-controlled trials | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Intra-articular injection of hyaluronic acid is a common, yet controversial, therapeutic option for patients with knee osteoarthritis (OA). The purpose of this research was to determine the safety and efficacy of US-approved viscosupplements for symptomatic knee OA.
METHODS: We searched MedLine and EMBase f... |
0 | The learning curve for adopting hip resurfacing among hip specialists | Management of Hip Fractures in the Elderly | Patient demand and surgeon interest in hip resurfacing has recently increased, but surgeons in the United States are relatively inexperienced with this procedure. We determined the learning curve associated with hip resurfacing and compared the rate of early complications of the first 650 hip resurfacings between five ... |
0 | Free vascularized bone transfers for nonunions, segmental gaps, and following tumor resection | DoD SSI (Surgical Site Infections) | Free vascularized bone transfer is recognized as a valuable technique for skeletal reconstruction and salvage with certain nonunions, skeletal defects, and following tumor resection. This procedure is most often indicated for reconstruction of lengthy skeletal defects or under circumstances where conventional bone graf... |
0 | Are we any closer to beating the biofilm: Novel methods of biofilm control | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Purpose Of Review: A multidisciplinary approach to the treatment and management of biofilms has resulted from the growing appreciation of the role that biofilms play in modern medicine. Conventional antimicrobial agents are generally ineffective against biofilms, and as a result novel laboratory-based and clinical stra... |
0 | Pamidronate induces bone formation in patients with smouldering or indolent myeloma, with no significant anti-tumour effect | MSTS 2018 - Femur Mets and MM | Twelve patients with smouldering or indolent multiple myeloma (MM) received 12 courses of intravenous pamidronate as a single agent to evaluate both the antitumour and bone metabolism effects. One patient achieved minor response, eight had stable disease, and three - all indolent MM - showed disease progression. Serum ... |
1 | The association between bifid median nerve and carpal tunnel syndrome: Is it really a risk factor? | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Objectives: This study aims to determine the bifid median nerve (BMN) frequency in patients with carpal tunnel syndrome (CTS) and to investigate the possible association between CTS and BMN in this patient population. Patients and methods: A total of 194 wrists of 131 patients in whom CTS was diagnosed clinically and e... |
0 | Trends in total elbow arthroplasty in the Medicare population: a nationwide study of records from 2005 to 2012 | Pediatric Supracondylar Humerus Fracture 2020 Review | Background Utilization of total elbow arthroplasty (TEA) has reportedly increased in recent years. Since the introduction of disease-modifying antirheumatic drugs, there has been a reported decline in its use among rheumatoid patients; yet, the shift in indications for TEA remains unclear. This study evaluated trends i... |
0 | Return to activities after breast reduction | Reduction Mammoplasty for Female Breast Hypertrophy | Background: Uncertainty exists in the medical literature about recommendations for return to work or driving after breast reduction surgery. Methods: A survey was sent to 138 plastic surgeons in the United Kingdom enquiring about their recommended timing of return to work or driving a car depending of level of activity... |
0 | Navigated femoral shaft fracture treatment: current status | DoD SSI (Surgical Site Infections) | Femoral malrotation is a common complication after internal fixation of a femoral shaft fracture. The only valid, objective monitoring method is computer tomography-assisted torsion measurement between the proximal and distal femur; unfortunately, this can only be carried out postoperatively. A difference of 15degree c... |
0 | Late results after meniscectomy in children | Diagnosis and Treatment of Osteochondritis Dissecans AUC | Seventy-five children undergoing 77 meniscectomies have been reviewed from 1 to 30 years (mean 15) after operation in order to determine the late results of meniscectomy. Arthroscopy of the patients with a poor result was performed at the follow-up. In 30 per cent osteoarthrosis was diagnosed, all with follow-up times ... |
0 | Sonographic evaluation of the medial aspect of the knee in a population-based cohort study | AMP (Acute Meniscal Pathology) | PURPOSE: The aim of this study was to evaluate the medial aspect of the knee with ultrasound (US).
METHODS: This study included 71 men and 154 women (450 knees) with a mean age of 65 years. US was used to evaluate the medial joint space of both knees with and without weight-bearing. In each subject, the medial radial d... |
0 | Bone loss after heart transplant: effect of alendronate, etidronate, calcitonin, and calcium plus vitamin D3 | Management of Hip Fractures in the Elderly | OBJECTIVE: To compare the effects of calcitonin, etidronate, and alendronate in preventing bone loss during the first 2 years after heart transplant. METHODS: A total of 222 heart transplant recipients (mean [SD] age, 52.4 [10] years, 85% male) were evaluated. Patients with normal bone mineral density (reference group,... |
0 | A subacute combined degeneration-like syndrome in the setting of zinc toxicity with normal serum copper | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | OBJECTIVE: To report a subacute combined degeneration-like syndrome with zinc toxicity and normal serum copper. BACKGROUND: Copper deficiency is a well-described cause of myelopathy with prominent sensory ataxia. Zinc overload results in excessive elimination of copper in enterocytes |
0 | Biofilm formation mechanisms and targets for developing antibiofilm agents | Dental Implant Infection | Biofilms are communities of microorganisms that are attached to a surface and play a significant role in the persistence of bacterial infections. Bacteria within a biofilm are several orders of magnitude more resistant to antibiotics, compared with planktonic bacteria. Thus far, no drugs are in clinical use that specif... |
0 | Surgical delay in acute admissions on warfarin: are we doing enough? | Management of Hip Fractures in the Elderly | Warfarin anti-coagulation can cause significant delay in acute surgical admissions. We reviewed fracture neck of femur patients operated over a period of 4 years in our unit. There was an average delay to surgery of 4.36 days in patients on warfarin as against an average delay of 1.78 days in patients not on warfarin (... |
0 | Bisphosphonate-induced periprosthetic fracture: a cause of painful total hip arthroplasty | PJI DX Updated Search | Background. Cases have been reported in the literature of periprosthetic fractures associated with the use of bisphosphonates occurring in the long term following a Total Hip Replacement (THR). We report an interesting case of periprosthetic fracture secondary to bisphosphonate use only a few months after a THR. Case R... |
1 | Neonatal hip screening | Developmental Dysplasia of the Hip CPG | CONTEXT: A "missed" case of congenital hip dislocation (CDH) can be a disaster for the patient and the outcome may be poor. Considerable resources are expended on screening programmes to identify appropriate cases early but a recent change in terminology to developmental dysplasia of the hip (DDH) and a realisation tha... |
0 | Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis | MSTS 2018 - Femur Mets and MM | Aberrant TGFbeta signaling is common in human cancers and contributes to tumor metastasis. Here, we demonstrate that Gr-1+CD11b+ myeloid cells are recruited into mammary carcinomas with type II TGF beta receptor gene (Tgfbr2) deletion and directly promote tumor metastasis. Gr-1+CD11b+ cells infiltrate into the invasive... |
0 | Neck of Femur Fracture in a Patient with a Chronic Osteomyelitis of the Ipsilateral Foot | DoD LSA (Limb Salvage vs Amputation) | This case report describes a successful two-stage treatment in a 75-year-old male with a displaced neck of femur fracture, also suffering from an active chronic osteomyelitis of the ipsilateral calcaneus. In our case, a below-knee amputation was performed first, followed by total hip arthroplasty two weeks later. At 15... |
1 | Reverse shoulder arthroplasty for massive irreparable rotator cuff tears and cuff tear arthropathy: a systematic review | Trial Systematic Review Project | PURPOSE: To report the outcomes and complications of reverse shoulder arthroplasty (RSA) in massive irreparable rotator cuff tears (MIRCT) and cuff tear arthropathy (CTA).
METHODS: A systematic review of the literature contained in Medline, Cochrane, EMBASE, Google Scholar and Ovid databases was conducted on May 1, 201... |
0 | Musculoskeletal rehabilitation: current understandings and future directions | HipFx Supplemental Cost Analysis | This work examines the current state of knowledge regarding the efficacy of rehabilitation for patients with major lower-extremity joint replacements, hip fractures, and amputations. Of particular focus is the use of inpatient rehabilitation strategies for functional restoration. These areas of rehabilitation involve c... |
0 | Platelet aggregation inhibitors, platelet function testing, and blood loss in hip fracture surgery | AAHKS (8) Anesthetic Infiltration | Background: The purpose of our prospective study was to analyze how many patients with hip fractures are on treatment with platelet aggregation inhibitors (aspirin and clopidogrel), how many of these patients have impaired platelet function as measured by the PFA-100, and whether there is an association between periope... |
0 | Covering of calf and foot defects by microsurgical techniques (free flaps) | DoD LSA (Limb Salvage vs Amputation) | Introduction: The progress seen in the treatment of traumas allows the rescue of the severely lesioned inferior limbs, which used to have primary amputation indication or were considered as lethal. The essential condition for this attitude is the adequate covering with soft tissues in the immediate period after the tra... |
1 | Evolving clinical and scientific concepts of upper extremity electrical trauma | DOD - Acute Comp Syndrome CPG | In conclusion, the pathogenesis of electrical injury is more complex than previously thought. Cellular damage occurs both by heating and electroporation. The relative contributions of heat and electroporation depend on the duration of electric current passage, the orientation of the cells, their location, and other fac... |
1 | Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery | Reduction Mammoplasty for Female Breast Hypertrophy | We assessed the efficacy of perioperative antibiotic prophylaxis for surgery in a randomized, double-blind trial of 1218 patients undergoing herniorrhaphy or surgery involving the breast, including excision of a breast mass, mastectomy, reduction mammoplasty, and axillary-node dissection. The prophylactic regimen was a... |
0 | Does short-wave diathermy increase the effectiveness of isokinetic exercise on pain, function, knee muscle strength, quality of life, and depression in the patients with knee osteoarthritis? A randomized controlled clinical study | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Knee osteoarthritis (OA) is a painful condition causing disability and muscle weakness. Shortwave diathermy (SWD) is one of several physical therapy modalities and used predominantly as a pain reduction modality in the clinical practice. However, the efficacy of SWD in knee OA is still inconclusive. AIM: Th... |
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