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The use of autologous platelet-rich plasma (platelet gel) and autologous platelet-poor plasma (fibrin glue) in cosmetic surgery
Reduction Mammoplasty for Female Breast Hypertrophy
The purpose of this study was to evaluate a new technique of harvesting and preparing autologous platelet gel and autologous fibrin glue (body glue) and to evaluate their effectiveness in stopping capillary bleeding in the surgical flaps of patients undergoing cosmetic surgery. A convenience sample of 20 patients rangi...
0
Development and validation of a SEER-based prognostic nomogram for patients with bone metastatic prostate cancer
MSTS 2022 - Metastatic Disease of the Humerus
Controversies exist between the previous two prognostic nomograms for patients with bone metastatic prostate cancer (PCa), and a nomogram applied to western patients has yet to be established. Thus, we aimed to build a reliable and generic nomogram to individualize prognosis. The independent prognostic factors were ide...
0
Sudden appearance and spontaneous regression of diffuse large B cell lymphoma in a man with a broken arm
MSTS 2022 - Metastatic Disease of the Humerus
An elderly, demented man with stable kappa bi-clonal gammopathy of unknown significance suffered a severe displaced right humeral fracture in a fall. One week later a rapidly enlarging head, neck and axillary adenopathy first appeared, including a 2 cm tonsillar node that partially obstructed the oropharynx. A left cer...
0
Does parallel item content on WOMAC's pain and function subscales limit its ability to detect change in functional status?
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Although the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) is considered the leading outcome measure for patients with osteoarthritis of the lower extremity, recent work has challenged its factorial validity and the physical function subscale's ability to detect valid change when pain...
0
The Role of Bisphosphonates in the Management of Patients That Have Cancer
MSTS 2018 - Femur Mets and MM
Bisphosphonates are pharmacologic agents widely used in people for managing pathologic bone resorptive conditions. Based on their physicochemical properties, bisphosphonates concentrate within areas of active bone remodeling and induce osteoclast apoptosis. Appropriate use of bisphosphonates for treating companion anim...
0
An idiopathic gigantomastia
Reduction Mammoplasty for Female Breast Hypertrophy
Gigantomastia is a rare condition characterized by excessive breast growth. It has been reported that the majority of gigantomastia cases occur during either pregnancy or puberty. We were presented with a rare case of gigantomastia associated with neither pregnancy nor puberty, and successfully treated it with reductio...
1
Adverse effect profile comparison of pain regimens with and without intravenous acetaminophen in total hip and knee arthroplasty patients
AAHKS (4) Acetaminophen
BACKGROUND: The use of adjunct, non-opioid agents is integral for pain control following total hip and knee arthroplasty. Literature comparing safety profiles of intravenous acetaminophen versus opioids is lacking. OBJECTIVE: To determine whether there is a difference in frequency and type of adverse effects between in...
0
Autogenous onlay graft with compression plate for treatment of persistent humeral shaft aseptic non-union with failed previous surgery
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: The humeral shaft fractures have a good rate of union, despite this fact, still there is a significant rate of nonunion after nonoperative treatment and more often after operative treatment. AIM: The aim of the study is to evaluate the autogenous onlay graft with compression plate for treatment of persisten...
0
Patient beliefs and perceptions play a crucial role in the decision-making process when managing a meniscal tear. A qualitative systematic review of the literature
AMP (Acute Meniscal Pathology)
INTRODUCTION: There has been an increase in research on the effectiveness of treatment options for the management of meniscal tears. However, there is very little evidence about the patient experiences of meniscal tears. AIM: To summarise the available qualitative evidence on patients' experiences and expectations of m...
0
Osimertinib for Previously Treated Patients With Advanced EGFR T790M Mutation-Positive NSCLC: Tolerability and Diagnostic Methods From an Expanded Access Program
MSTS 2018 - Femur Mets and MM
Introduction: The osimertinib (AZD9291) US Expanded Access Program (EAP) provided compassionate access to osimertinib prior to US Food and Drug Administration (FDA) approval for patients with advanced/metastatic epidermal growth factor receptor (EGFR) T790M-positive non-small cell lung cancer (NSCLC) following progress...
0
Stress fracture of the hip. An unusual complication of total knee arthroplasty
Management of Hip Fractures in the Elderly
Stress fracture of the hip is a rare complication of total knee arthroplasty (TKA). Only eight cases seem to have been reported in the literature. A ninth case is reported in the present study. A 76-year-old obese woman was treated by right TKA for osteoarthrosis with cementing of the tibial component because of insuff...
0
Functional status and well-being in patients with glaucoma as measured by the Medical Outcomes Study Short Form-36 questionnaire
Upper Eyelid and Brow Surgery
PURPOSE: This study aimed to determine whether patients with glaucoma have different functional status and well-being than patients without glaucoma. DESIGN: Prospective case-control study. PARTICIPANTS: The study population was recruited from 2 university-based glaucoma clinical practices and a university-based genera...
0
Preoperative Pain and Function Profiles Reflect Consistent TKA Patient Selection Among US Surgeons
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: As the number of primary total knee arthroplasties (TKAs) performed in the United States increases, policymakers have questioned whether the indications and timing of TKA have evolved so that surgery is offered earlier. QUESTIONS/PURPOSES: We analyzed data from a US national TKA cohort to evaluate variation...
0
External fixation as a bridge to intramedullary nailing for patients with multiple injuries and with femur fractures: Damage control orthopedics
DoD LSA (Limb Salvage vs Amputation)
Background: The advantages of early fracture fixation in patients with multiple injuries have been challenged recently, particularly in patients with head injury. External fixation (EF) has been used to stabilize pelvic fractures after multiple injury. It potentially offers similar benefits to intramedullary nail (IMN)...
0
Application of Advanced Magnetic Resonance Imaging Techniques in Evaluation of the Lower Extremity
AMP (Acute Meniscal Pathology)
This article reviews current magnetic resonance imaging (MR imaging) techniques for imaging the lower extremity, focusing on imaging of the knee, ankle, and hip joints. Recent advancements in MR imaging include imaging at 7 T, using multiple receiver channels, T2* imaging, and metal suppression techniques, allowing mor...
0
Age does not influence the clinical outcome after high tibial osteotomy
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: Valgus high tibial osteotomy (HTO) is an established procedure for the medial gonarthrosis. In several studies, many negative influencing factors were evaluated. However, until now, the factor "age" was examined only insufficiently. The aim of our study was to evaluate the factor age in predicting the function...
0
Cryotherapy following total knee replacement
OAK 3 - Non-arthroplasty tx of OAK
Total knee replacement (TKR) is a common intervention for patients with end-stage osteoarthritis of the knee. Post-surgical management may include cryotherapy. However, the effectiveness of cryotherapy is unclear. To evaluate the acute (within 48 hours) application of cryotherapy following TKR on pain, blood loss and f...
0
Prevention and management of hip fracture in older patients
Management of Hip Fractures in the Elderly
The average age at hip fracture is 83 for women and 84 for men, with about 80% of cases in women. The 30% mortality and 20% new institutionalisation rates at 12 months reflect the high prevalence of comorbidity and to some extent suboptimal management at the time of the fracture. With timely intervention and better cli...
0
Chronic compartment syndrome. An unusual cause for claudication
DOD - Acute Comp Syndrome CPG
Chronic Compartment Syndrome (CCS) is usually caused by overuse injury in well-conditioned athletes (particularly runners). Less common causes of CCS include blunt trauma, venous insufficiency, and tumor. CCS is clinically manifested as claudication, tightness, and occasional paresthesia. Unlike other forms of overuse ...
0
Patterns of survival in patients with recurrent follicular lymphoma: a 20-year study from a single center
MSTS 2022 - Metastatic Disease of the Humerus
PURPOSE: To examine outcome of treatment for patients with recurrent follicular lymphoma. PATIENTS AND METHODS: Two hundred twelve newly diagnosed follicular lymphoma patients were studied. One hundred seventy-nine were initially treated successfully. Recurrent or progressive lymphoma developed in 116. Treatment was gi...
0
Lateral collateral ligament instability of the elbow
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Lateral elbow support is provided by a combination of bony anatomy and the ligaments and tendons that originate at the lateral epicondyle. Instability is typically posttraumatic in nature. In the acute setting of elbow fracture-dislocation, restoration of lateral soft tissue support can be typically accomplished by a d...
0
Traditional distance â??tip-apexâ?쳌 vs. new calcar referenced â??tip-apexâ?쳌 - which one is the best peritrochanteric osteosynthesis failure predictor?
Hip Fx in the Elderly 2019
Introduction: In the treatment of trochanteric fractures, the distance between the tip of the screw and the apex of the femoral head or tip-to-apex distance (TAD) was popularized by Baumgaertner about 20 years ago as an important predictor of failure. Recently, a new reference point for determining the apex has been ad...
0
The use of two nutritional indicators in identifying long bone fracture patients who do and do not develop infections
DoD SSI (Surgical Site Infections)
One hundred consecutive orthopedic long bone fracture patients requiring surgical fixation were nutritionally assessed using both the nutritional index of Rainey-MacDonald et al. and total lymphocyte count. The ability of these two parameters to identify correctly those patients who do and do not develop postoperative ...
0
Fishtail deformity following fracture of the distal humerus in children: historical review, case presentations, discussion of etiology, and thoughts on treatment
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Fishtail deformity is an uncommon complication of distal humeral fractures in children. This article reports four cases accompanied by premature closure of a portion of the distal humeral physis with resultant deformity, length retardation, decreased elbow motion, and functional impairment. The ages of the patients at ...
0
Long-term results of hybrid alumina-on-alumina total hip arthroplasty: 10-14-Year results
PJI DX Updated Search
Between 2000 and 2004, 89 hybrid alumina-on-alumina hip replacements were performed by a single surgeon. There were 46 men and 43 women with an average age of 51 years. All patients were followed up for a minimum of 10 years. Prior to surgery, the mean Harris hip score (HHS) was 44 points (35-55). Following surgery, th...
0
The consequences of complacency: Managing the effects of unrecognized Charcot feet
DoD LSA (Limb Salvage vs Amputation)
Aims Several authors have discussed an early prodromal state of neuroarthropathy (stage 0 Charcot) prior to the development of frank radiographic changes. However, very few reports are available that detail the outcomes of these patients. The purpose of this study was to report on the outcomes of patients with undetect...
1
The effectiveness of supplementing a standard rehabilitation program with superimposed neuromuscular electrical stimulation after anterior cruciate ligament reconstruction: a prospective, randomized, single-blind study
Anterior Cruciate Ligament Injuries CPG
BACKGROUND: Rehabilitation after anterior cruciate ligament reconstruction is a key determinant affecting patient return to usual activity levels. Neuromuscular electrical stimulation is a treatment that can counteract strength loss and serve as an adjunct to conventional therapy. PURPOSE: To compare the effect of addi...
0
Molecular diagnosis of periprosthetic joint infection by quantitative RT-PCR of bacterial 16S ribosomal RNA
PJI DX Updated Search
The diagnosis of periprosthetic joint infection is sometimes straightforward with purulent discharge from the fistula tract communicating to the joint prosthesis. However it is often difficult to differentiate septic from aseptic loosening of prosthesis because of the high culture-negative rates in conventional microbi...
1
Modulation of Synovial Fluid-Derived Mesenchymal Stem Cells by Intra-Articular and Intraosseous Platelet Rich Plasma Administration
PRP (Platelet-Rich Plasma)
The aim of this study was to evaluate the effect of intra-articular (IA) or a combination of intra-articular and intraosseous (IO) infiltration of Platelet Rich Plasma (PRP) on the cellular content of synovial fluid (SF) of osteoarthritic patients. Thirty-one patients received a single infiltration of PRP either in the...
0
Essentials of anterior cruciate ligament rupture management
Surgical Management of Osteoarthritis of the Knee CPG
Anterior cruciate ligament (ACL) rupture is a common knee injury and an understanding of current medical knowledge regarding its management is essential. Accurate and prompt diagnosis requires an awareness of injury mechanisms and risk factors, common symptoms and physical/radiologic findings. Early mobilization and ph...
0
The transplantation of particulated juvenile allograft cartilage and synovium for the repair of meniscal defect in a lapine model
AMP (Acute Meniscal Pathology)
Background: Synovium has been confirmed to be the primary contributor to meniscal repair. Particulated Juvenile Allograft Cartilage (PJAC) has demonstrated promising clinical effect on repairing cartilage. The synergistic effect of synovium and PJAC transplant on meniscal fibrocartilaginous repair is unclear. We hypoth...
0
Association between the +104T/C polymorphism in the 5'UTR of GDF5 and susceptibility to knee osteoarthritis: a meta-analysis
OAK 3 - Non-arthroplasty tx of OAK
Although the +104T/C polymorphism in the 5' untranslated region (UTR) of growth differentiation factor 5 (GDF5) plays a role in the pathogenesis of knee osteoarthritis, the results have been inconsistent. In this study, we performed a meta-analysis to assess the association of +104T/C polymorphism with knee osteoarthri...
0
Social work and the management of severe head injury
DoD PRF (Psychosocial RF)
This article examines the role of the health social worker in the management of the psychosocial sequelae of head injury from the membership perspective. Data relative to the incidence and medical dimensions of head injury and its psychosocial sequelae are briefly reviewed. The social work definition of head injury as ...
0
Retrospective analysis of extra-articular distal humerus shaft fractures treated with the use of pre-contoured lateral column metaphyseal LCP by triceps-sparing posterolateral approach
Distal Radius Fractures
Management of extra-articular distal humerus fractures presents a challenge to the treating surgeon due to the complex anatomy of the distal part of the humerus and complicated fracture morphology. Although surgical treatment has shown to provide a more stable reduction and alignment and predictable return to function,...
0
Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)
TO: WNT2 Pathway Modulator
The purpose of this study is to find the optimal dose of SM04690 that can be safely given by intra�articular injection into the target knee joint of subjects with moderate to severe osteoarthritis.
0
Infrequent attendance in general practice after a major disaster: a problem? A longitudinal study using medical records and self-reported distress and functioning
DoD PRF (Psychosocial RF)
OBJECTIVE: To assess the characteristics and implications for care of infrequent attendance in general practice in the aftermath of disaster. METHODS: A study of the content of electronic medical records (EMRs) in pre- and post-disaster periods linked to an enquiry using self-reported questionnaires administered 3 week...
0
Stem Cells for Treatment of Musculoskeletal Conditions - Orthopaedic/Sports Medicine Applications
OAK 3 - Non-arthroplasty tx of OAK
A myriad of musculoskeletal conditions afflicts a vast number of the world's population from birth to death. Countless pathological diseases and traumatic injuries (acute and chronic) contribute to different human disabilities, causing a tremendous financial toll on the economy of healthcare. The medical field is conti...
0
Internal fixation and comparisons of different fixation methods for treating distal radial fractures in adults
Management of Hip Fractures in the Elderly
This is the protocol for a review and there is no abstract. The objectives are as follows:To evaluate the effectiveness of internal fixation for fractures of the distal radius in skeletally mature people. Additionally, to evaluate the relative effectiveness of different surgical methods of treating these fractures.More...
0
Total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Eighty-six nonhinged total knee arthroplasties performed between 1971 and 1981 have been reviewed. Fifty-one were of the geometric type and 35 of the anametric type. The use of both units resulted in a statistically and clinically significant improvement in preoperative pain and an increase in functional activities. Th...
0
TKR patients with prior ipsilateral menisectomy are younger and have significant pain and disability
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: Total knee replacement (TKR) use is projected to increase by 673% by the year 2020 as the US population ages. Moreover, TKR demand in adults under 65 years of age is projected to significantly increase in the next decade. The surge in older and younger osteoarthritis (OA) patients will overlap in the next deca...
0
Incidence and Characteristics of Meniscal Injuries in Cadets at a Military School, 2013-2015
AMP (Acute Meniscal Pathology)
CONTEXT: Meniscal injury is common among military service members. OBJECTIVE: To examine the incidence and characteristics of meniscal injuries in cadets at a single military institution between 2013 and 2015. DESIGN: Cohort study. SETTING: Meniscal-injury data were collected at the Center of Rehabilitation Training, t...
0
The Effects of Collateral Meridian Therapy for Knee Osteoarthritis Pain Management
AAHKS (2) Corticosteroids
Knee OA patients aged 60 years or older were recruited from the orthopedic clinic of Taichung Armed Force General Hospital, Taichung, Taiwan. All the patients had been clinically and radiologically diagnosed with knee OA according to the criteria of the American College of Rheumatology and Lawrence radiographic changes...
0
Transient bacteremia associated with diagnostic and therapeutic procedures
Dental Implant Infection
In general, all individuals known to have valvular heart disease should be considered candidates for prophylaxis. With dental and urinary tract procedures, the frequency of bacteremia seems sufficiently high to warrant antimicrobial prophylaxis. The value of prophylaxis is uncertain in procedures less commonly associat...
0
Evaluation of socket healing in patients undergoing bisphosphonate therapy: Experience of a single Institution
MSTS 2018 - Femur Mets and MM
Objective: To assess the clinical features of exodontias performed in cancer patients who have been receiving intravenous bisphosphonates (BPs). Study Design: This is a retrospective cohort study using a sample of 20 patients receiving BPs who had 62 teeth extracted. An univariate analysis was applied to calculate sock...
0
Quality of Relationships With Caregivers, Depression, and Life Satisfaction After Dysvascular Lower Extremity Amputation
DoD LSA (Limb Salvage vs Amputation)
OBJECTIVE: To describe the relationship between caregiver-specific support and conflict, and psychosocial outcomes among individuals experiencing their first dysvascular lower extremity amputation (LEA). DESIGN: Cross-sectional cohort study using self-report surveys. SETTING: Department of Veterans Affairs, academic me...
0
Computer-telephone interactive tasks: Predictors of musculoskeletal disorders according to work analysis and workers' perception
DoD PRF (Psychosocial RF)
Sixty-two workers engaged in computer-telephone interactive tasks in an active telemarketing center and a telephone call center of an international bank subsidiary in São Paulo, Brazil, were assessed by means of a work analysis and a self-administered questionnaire aiming to determine the statistical relationship of e...
0
Patient controlled epidural analgesia for bilateral versus unilateral total knee arthroplasty: A retrospective study of pain control
AAHKS (8) Anesthetic Infiltration
Background: Patient controlled epidural analgesia (PCEA) has been used commonly for postoperative pain management following total knee arthroplasty (TKA). The purpose of this study was to compare a single standardized PCEA protocol in patients who received unilateral TKA with patients who received simultaneous bilatera...
0
Knowledge transfer in surgery: Skills, process and evaluation
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Introduction: Knowledge transfer is an essential element in the management of surgical health care. In a routine clinical practice, surgeons need to make changes to the health care they provide as new clinical evidence emerges. Materials and methods: The information was derived from the authors' experience and research...
0
Trigger fingers: A review
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Trigger finger, or stenosing tendovaginitis, is a common problem that has its origin at the level of the first annular pulley of the digital flexor tendon sheath. A size discrepancy between the sheath and tendon interferes with the normal tendon gliding process, causing pain and/or snapping upon extension. This article...
0
Recommendations on diagnosis and treatment in hepatobiliary surgery under 2019-nCoV epidemic
Coronavirus Disease 2019 (COVID-19)
2019 novel coronavirus pneumonia is a serious life-threatening disease and it has affected many people globally, especially the people who live in China. A high prevalence of hepatobiliary diseases has been observed in 2019-nCoV patients and some may require emergency surgery. In the context of the novel coronavirus pn...
0
Human Immunodeficiency Virus and Total Joint Arthroplasty: The Risk for Infection Is Reduced
PJI DX Updated Search
BACKGROUND: Highly active antiretroviral therapy (HAART) has changed the face of human immunodeficiency virus (HIV) and allowed patients to live for many decades. HIV and HAART are known risk factors for osteonecrosis of bone, osteopenia, and osteoporosis. Therefore, the demand for total joint arthroplasty (TJA) in HIV...
0
Treatment options other than total knee arthroplasty in young patients with knee osteoarthritis: Part II
OAK 3 - Non-arthroplasty tx of OAK
Symptomatic articular knee pathology is not isolated to the aged but also affects younger patients. Although total knee arthroplasty (TKA) remains the gold standard treatment, surgery for gonarthrosis is frequently eschewed in younger patients because of concerns over activity limitations and implant longevity. Further...
0
Gender differences in functional outcome of elderly hip fracture patients
Hip Fx in the Elderly 2019
AIM: The purpose of the present study was to investigate whether gender might affect functional outcome of hip fractured patients undergoing in-hospital rehabilitation. METHODS: This was a retrospective chart review study comprising of 759 consecutive elderly patients suffering traumatic hip fracture. All patients unde...
0
Early experiences of breast-conservation treatment combined with tamoxifen and CAF chemotherapy for breast cancer of stages I and II
MSTS 2018 - Femur Mets and MM
A total of 39 patients with breast cancer of stages I and II received breast-conservation treatment (BCT) combined with tamoxifen and systemic chemotherapy (CAF) from August 1989 to March 1993. All of these patients visited the outpatient clinic of the Department of Radiology of Kochi Medical School Hospital, with an o...
0
The effects of radioisotope therapy and radiotherapy in subjects with breast cancer with bone metastases
MSTS 2018 - Femur Mets and MM
Background: Metastatic bone disease is found in 80-90% of patients examined after death and is a serious problem in everyday practice. The aim of the study was the evaluation of the survival time of patients with bone metastases in relation to the prognostic group and applied treatment. Material and Methods: The author...
0
Bone marrow microvascular density and angiogenic growth factors in multiple myeloma
MSTS 2018 - Femur Mets and MM
There is evidence that angiogenesis plays an important role in the progression of multiple myeloma (MM). Hepatocyte growth factor (HGF) and tumor necrosis factor-α (TNF-α) are cytokines that potently stimulate angiogenesis. We evaluated the microvascular density (MVD) of bone marrow biopsies (after immunostaining wit...
0
Leukocyte and Platelet Rich Plasma (L-PRP) Versus Leukocyte and Platelet Rich Fibrin (L-PRF) For Articular Cartilage Repair of the Knee: A Comparative Evaluation in an Animal Model
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Articular cartilage injuries of the knee are among the most debilitating injuries leading to osteoarthritis due to limited regenerative capability of cartilaginous tissue. The use of platelet concentrates containing necessary growth factors for cartilage healing has recently emerged as a new treatment metho...
0
Bilateral gluteal compartment syndrome following right total knee revision: a case report
PJI DX Updated Search
BACKGROUND: Gluteal compartment syndrome is a rare occurrence traditionally found in settings of extended immobilization. Thrombolytics and medications with myositis as a potential side effect have also been implicated in a few isolated cases of spontaneous compartment syndrome. Early signs are pain on passive stretchi...
0
CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis
MSTS 2018 - Femur Mets and MM
Pancreatic ductal adenocarcinoma is an unsolved health problem with nearly 75% of patients diagnosed with advanced disease and an overall 5-year survival rate near 5%. Despite the strong link between mortality and malignancy, the mechanisms behind pancreatic cancer dissemination and metastasis are poorly understood. Co...
0
Anesthesia for the patient undergoing total knee replacement: current status and future prospects
AAHKS (9/10) Regional Nerve Blocks
Total knee arthroplasty (TKA) has become one of the most common orthopedic surgical procedures performed nationally. As the population and surgical techniques for TKAs have evolved over time, so have the anesthesia and analgesia used for these procedures. General anesthesia has been the dominant form of anesthesia util...
0
Treatment Outcomes of Lesser Tuberosity Osteotomy Nonunion After Total Shoulder Arthroplasty
Glenohumeral Joint OA
Introduction: Lesser tuberosity osteotomy (LTO) during anatomic total shoulder arthroplasty has a 13% nonunion rate. Treatment for LTO nonunion is controversial and poorly described in the literature. The purpose of this study was to compare the surgical and nonsurgical treatment outcomes of LTO nonunion. Methods: A re...
0
Hereditary hemochromatosis as a risk factor for joint replacement surgery
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: Hemochromatosis is an inherited disease with iron overload and joint involvement resembling osteoarthritis. To determine the rate of joint replacement surgery in patients with hemochromatosis, we performed a cross-sectional cohort study. METHODS: A total of 199 individuals with hereditary hemochromatosis wer...
0
Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidism in elderly women
Management of Hip Fractures in the Elderly
Long-term vitamin D and calcium supplementation is effective in reducing nonvertebral fractures in elderly people. Increased bone fragility caused by secondary hyperparathyroidism (sHPT) and impaired balance are known risk factors for hip fractures. The hypothesis is that short-term therapy with calcium and vitamin D m...
0
Prevalence of carpal tunnel syndrome in pregnancy
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Introduction: Carpal Tunnel Syndrome (CTS) is one of the complications that may occur during pregnancy and puerperium, most commonly in the third trimester of pregnancy. This dysfunction is due to the median nerve compression in the carpal tunnel and the symptoms usually presented are tingling, pain and paresthesia in ...
0
Periodontal infections and cardiovascular disease--how strong is the association?
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
In the past decade there has been renewed interest in the old hypothesis that infections increase the risk of developing cardiovascular disease and stroke. There is now a convincing body of evidence that atherosclerosis has a major inflammatory component and is much more than the simple vascular accumulation of lipids....
0
Surgery for weight loss in adults
Surgical Management of Osteoarthritis of the Knee CPG
Background: Bariatric (weight loss) surgery for obesity is considered when other treatments have failed. The effects of the available bariatric procedures compared with medical management and with each other are uncertain. This is an update of a Cochrane review first published in 2003 and most recently updated in 2009....
0
Walking recovery after a hip fracture: a prospective follow-up study among community-dwelling over 60-year old men and women
Hip Fx in the Elderly 2019
PURPOSE: Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. METHODS: A prospective follow-up study, among clinica...
0
Biopsy vs. peripheral computed tomography to assess bone disease in CKD patients on dialysis: differences and similarities
Distal Radius Fractures
Results from bone biopsy and high-resolution peripheral quantitative computed tomography (HR-pQCT) were compared in 31 CKD patients. There was an agreement mainly for cortical compartment that may represent a perspective on the fracture risk assessment. HR-pQCT also provided some clues on the turnover status, which war...
0
Two-stage revision arthroplasty of the hip for infection using an interim articulated Prostalac hip spacer: a 10- to 15-year follow-up study
PJI DX Updated Search
We report the outcome at ten to 15 years of two-stage revision for hip infection in 99 patients using the Prostalac articulated hip spacer system. All the patients were contacted to determine their current functional and infection status using the Oxford-12, Short form-12, and Western Ontario and McMaster University Os...
0
Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance
Management of Hip Fractures in the Elderly
Summary: This analysis of National Health and Nutrition Examination Survey III data found a significant risk of incident hip fracture in adults aged 65 years and older who are candidates for treatment to lower fracture risk, according to the new National Osteoporosis Foundation Clinician's Guide. Introduction: The rela...
0
Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults
SR for PM on OA of All Extremities
Background: This review is an update of a previously published review in The Cochrane Database of Systematic Reviews Issue 3, 2009 on single dose oral dexibuprofen (S(+)-ibuprofen) for acute postoperative pain in adults.Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID) licensed for use in rheumatic disease...
0
Hip fractures in two health care regions in Finland in 1989: an analysis of treatment
HipFx Supplemental Cost Analysis
We studied prospectively the demographic data, fracture types and modes of treatment in 390 patients with acute traumatic hip fractures in two health care regions in Finland, the Middle Finland region and the Kymenlaakso region in 1989. In Middle Finland population (251,203 inhabitants) 199 patients with a hip fracture...
0
Unsatisfactory outcome of arthrodesis performed after septic failure of revision total knee arthroplasty
DoD LSA (Limb Salvage vs Amputation)
BACKGROUND: Periprosthetic infection is one of the most dreaded orthopaedic complications. Current treatment procedures include one-stage or two-stage revision total knee arthroplasty. If the periprosthetic infection is no longer controllable after several revision total knee arthroplasties, many surgeons regard knee a...
0
Free tissue transfer: an advanced strategy for postinfection soft-tissue defects in the upper extremity
DoD LSA (Limb Salvage vs Amputation)
Surgical treatment of severe, necrotizing infections frequently leave compound defects that require complex reconstructive procedures. In the upper extremity, local flap coverage is limited because of the size of the lesions. Regarding the results of early microsurgical coverage of complex postinfectious defects of the...
0
Arthroscopic Capsular Plication in Patients With Labral Tears and Borderline Dysplasia of the Hip: Analysis of Risk Factors for Failure
Developmental Dysplasia of the Hip 2020 Review
BACKGROUND: Hip arthroscopy for the treatment of instability in the setting of borderline dysplasia is controversial. Capsular management in such cases is an important consideration, and plication has been described as a reliable technique, with good midterm outcomes reported when indications are appropriate. HYPOTHESI...
0
Failure characteristics of the isolated distal radius in response to dynamic impact loading
Distal Radius Fractures
We examined the mechanical response of the distal radius pre-fracture and at fracture under dynamic impact loads. The distal third of eight human cadaveric radii were potted and placed in a custom designed pneumatic impact system. The distal intraarticular surface of the radius rested against a model scaphoid and lunat...
1
What factors are associated with outcomes scores after surgical treatment of ankle fractures with a posterior malleolar fragment?
DoD SSI (Surgical Site Infections)
BackgroundPsychosocial factors, such as depression and catastrophic thinking, might account for more disability after various orthopaedic trauma pathologies than range of motion and other impairments. However, little is known about the influence of psychosocial aspects of illness on long-term symptoms and limitations o...
0
Histone modifications in the interluekin-6 gene promoter region of rheumatoid arthritis synovial fibroblasts
Surgical Management of Osteoarthritis of the Knee CPG
Background/Purpose: Rheumatoid arthritis (RA) is a disease of unknown origin, which develops continuous inflammation and progressive joint destruction resulting from an autoimmune response mainly occurred in the joints. Although genetic factors in RA have been reported, another factors might be important for RA because...
0
Acute knee effusions: a systematic approach to diagnosis
AMP (Acute Meniscal Pathology)
Knee effusions may be the result of trauma, overuse or systemic disease. An understanding of knee pathoanatomy is an invaluable part of making the correct diagnosis and formulating a treatment plan. Taking a thorough medical history is the key component of the evaluation. The most common traumatic causes of knee effusi...
0
Future of 34 meniscectomies after bucket-handle meniscus tear: a retrospective study with a follow-up over 22 years
AMP (Acute Meniscal Pathology)
After a bucket-handle meniscus tear, a partial meniscectomy by arthroscopy is recommended, when a meniscal suture is impossible. Short-term results of meniscectomy after bucket-handle meniscus tear, without cartilage or ligament additional injury, are mostly excellent: pain and blocking disappear, return to sports acti...
0
Elastase from polymorphonuclear leukocyte in articular cartilage and synovial fluids of patients with rheumatoid arthritis
Surgical Management of Osteoarthritis of the Knee CPG
Objective was to study the significance and the mechanism of action of elastase from polymorphonuclear leukocyte (PMN elastase) in patients with rheumatoid arthritis (RA). The experiments conducted consisted of two phases. Firstly, articular cartilage and synovia from 8 patients with RA undergoing total knee replacemen...
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Double-blind randomized controlled trial of flurbiprofen-SR (ANSAID-SR) and diclofenac sodium-SR (Voltaren-SR) in the treatment of osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
A six week, double�blind, randomized, parallel group, multicentre study was conducted in 85 patients with osteoarthritis of the knee and hip to compare the efficacy, tolerability, and safety of Flurbiprofen�SR 200 mg with Diclofenac Sodium�SR 100 mg. Between group comparisons, based on change scores from baseline...
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Can preoperative scoring systems be applied to Asian hip fracture populations? Validation of the Nottingham Hip Fracture Score (NHFS) and identification of preoperative risk factors in hip fractures
Hip Fx in the Elderly 2019
INTRODUCTION: Hip fractures in the elderly are a major cause of morbidity and mortality. Determining which patients will benefit from hip fracture surgery is crucial to reducing mortality and morbidity. Our objectives are: 1) to define the rate of index admission, 1-month and 1-year mortality in all hip fracture patien...
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Structural changes in muscle and glenohumeral joint deformity in neonatal brachial plexus palsy
Glenohumeral Joint OA
BACKGROUND: Internal rotation contracture of the shoulder is common in children with neonatal brachial plexus palsy. A long-standing contracture may cause osseous deformities in the developing shoulder. The purpose of the study was to evaluate the relationship between osseous deformities of the glenohumeral joint and s...
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Current issues and regulations in tendon regeneration and musculoskeletal repair with mesenchymal stem cells
AMP (Acute Meniscal Pathology)
Mesenchymal stem cells are multipotent stromal cells residing within the connective tissue of most organs. Their surface phenotype has been well described. Most commonly, mesenchymal stem cells demonstrate the ability to differentiate into mesenchymal tissues (bone, catailge, fat, etc.), however, under the proper condi...
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The use of epidural morphine in patients undergoing total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Sixty-six patients undergoing total knee arthroplasty were offered epidural morphine as a method of postoperative analgesia. Of the 66 patients, 50 completed the minimum protocol of 3 days in a special epidural monitoring unit and were thus available for study. In this study group, 86% stated that they obtained 75-100%...
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Epidemiology and management of osteoporosis in the People's Republic of China: current perspectives
Hip Fx in the Elderly 2019
With the progressive aging of the population, osteoporosis has gradually grown into a global health problem for men and women aged 50 years and older because of its consequences in terms of disabilities and fragility fractures. This is especially true in the People's Republic of China, which has the largest population ...
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Bone marrow edema in the knee in osteoarthrosis and association with total knee arthroplasty within a three-year follow-up
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: The purpose of this study was to determine if a correlation exists between magnetic resonance imaging (MRI) findings of bone marrow edema (BME) in osteoarthrosis (OA) of the knee joint and need for total knee arthroplasty (TKA) within a follow-up period of 3 years. MATERIALS AND METHODS: The entire database ...
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Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial
OAK 3 - Non-arthroplasty tx of OAK
Background: Osteoarthritis (OA) is a major clinical and public health problem, with no current medications approved as having disease modifying effects. HMG-CoA reductase inhibitors, or "statins", a drug class widely used to prevent cardiovascular events, could potentially affect OA progression via a number of mechanis...
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A novel biomarker in patients with knee osteoarthritis: adropin
OAK 3 - Non-arthroplasty tx of OAK
Adropin is newly discovered peptide hormone. Osteoarthritis (OA) is a kind of joint disease characterized by progressive joint cartilage loss and joint pain. The present study was carried out to investigate adropin and tumor necrosis factor alpha (TNF-alpha) levels and the relationship between adropin in patients with ...
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Control of postoperative pain following total knee arthroplasty: Is it necessary to associate sciatic nerve block to femoral nerve block?
AAHKS (9/10) Regional Nerve Blocks
BACKGROUND AND OBJECTIVES: Total knee arthroplasty (TKA) causes severe tissue trauma, leading to severe postoperative pain. Good postoperative analgesia is fundamental and one should consider that early mobilization of the joint is an important aspect to obtain good results. There is a controversy in the literature on ...
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Risk of falls in patients with knee osteoarthritis undergoing total knee arthroplasty: A systematic review and best evidence synthesis
OAK 3 - Non-arthroplasty tx of OAK
Objectives: Falls occur frequently in patients with impaired ambulation and may dramatically affect the elderly population. Aim was to document the incidence of falls in knee osteoarthritis (OA) patients undergoing total knee arthroplasty (TKA), and to identify factors and treatments that may influence the risk of fall...
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Posterior tibial slope accuracy with patient-specific cutting guides during total knee arthroplasty: A preliminary study of 50 cases
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Patient-specific cutting guides were recently introduced to facilitate total knee arthroplasty (TKA). Their accuracy in achieving optimal implant alignment remains controversial. The objective of this study was to evaluate postoperative radiographic outcomes of 50 TKA procedures with special attention to po...
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Serum C-reactive protein and procalcitonin kinetics in patients undergoing elective total hip arthroplasty
PJI DX Updated Search
BACKGROUND: The sensitivity and the specificity of different methods to detect periprosthetic infection have been questioned. The current study aimed to investigate the kinetics of C-reactive protein (CRP) and procalcitonin (PCT) in patients undergoing uncomplicated elective total hip arthroplasty (THA), to provide a b...
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Bartonella (Rochalimaea) quintana infection in a seronegative hemodialyzed patient
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Bartonella quintana is a reemerging pathogen responsible for trench fever, endocarditis, bacteremia, and bacillary angiomatosis. We previously reported the first case of a patient with B. quintana-induced chronic adenomegaly, and here we present a report on a second patient. A hemodialyzed patient with Sjogren's syndro...
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Analysis of inpatient costs in patients with knee osteoarthritis treated by implantation of total condylar knee endoprosthesis
OAK 3 - Non-arthroplasty tx of OAK
Background/Aim. Total knee replacement is an elective and high cost surgical procedure which is performed more frequently as a result of increasing prevalence of knee osteoarthritis. The aim of this study was to provide insight into the value and structure of inpatient costs associated with total knee replacement in Se...
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Mesenchymal cells inhibit expansion but not cytotoxicity exerted by gamma-delta T cells
MSTS 2018 - Femur Mets and MM
BACKGROUND: Multipotent mesenchymal stromal cells (MSCs) exert a relevant immunosuppressive activity by inhibiting T- and B-lymphocytes, natural killer (NK) cells and dendritic cell expansion. Nevertheless, a possible activity on gamma/delta T cells has still not been evaluated. Gamma-delta T lymphocytes play an import...
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Long-term results of high tibial osteotomy for medial osteoarthritis of the knee
Surgical Management of Osteoarthritis of the Knee CPG
We reviewed retrospectively the results in patients who had undergone one hundred and four high tibial lateral osteotomies. The operations were all performed between 1985 and 1993. Each one of fifty men and forty nine women demonstrated a varus deformity of the knee with a coexistent medial osteoarthritis. Results were...
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Bisphosphonates in oncology: physiopathologic bases and clinical activity
MSTS 2018 - Femur Mets and MM
Osteoclastic activation is the ultimate way of bone resorption in neoplasia, induced by the combined effects of tumor-secreted humoral factors (especially parathyroid hormone-related peptides) and osteoclastic-osteoblastic interaction. Bisphosphonates inhibit the osteoclast activity and reduce bone resorption and are a...
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Ultrasound versus synovial fluid analysis for the diagnosis of calcium pyrophosphate dihydrate deposition disease: Is IT CPPD? Ask US!
Surgical Management of Osteoarthritis of the Knee CPG
Background The diagnosis of calcium pyrophosphate crystal (CPP) deposition disease (CPPD) is mainly based on the synovial fluid analysis and Xrays. US has demonstrated high sensitivity and specificity values for diagnosing