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0 | Does local recurrence impact survival in low-grade chondrosarcoma of the long bones? | MSTS 2022 - Metastatic Disease of the Humerus | We hypothesized local recurrence of Grade 1 chondrosarcoma in the long bones of the extremity negatively influences survival. To explore that notion, we retrospectively reviewed 164 patients treated surgically for Grade 1 chondrosarcoma of the long bones. Local recurrence occurred in 21 (13%) patients. Four patients ha... |
0 | Musculoskeletal Hydatid Cysts Resembling Tumors: A Report of Five Cases | DoD SSI (Surgical Site Infections) | Although challenges in treatment of musculoskeletal hydatid cysts (HC) lesions have been documented, data regarding the musculoskeletal HC lesions resembling tumor is scarce. This paper presented 5 patients (3 males, 2 females) with a mean age of 41.6 years with tumor-like lesions of HC. Three of them had left ilium an... |
1 | Predictors of short-term mortality in critically ill patients with solid malignancies | MSTS 2022 - Metastatic Disease of the Humerus | UNLABELLED: Admission of cancer patients with serious medical complications to the ICU remains controversial primarily because of the high short-term mortality rates in these patients. However, the cancer patient population is heterogeneous regarding age, underlying conditions, and curability of their disease, suggesti... |
0 | The impact of patient-specific instrumentation on unicompartmental knee arthroplasty: a prospective randomised controlled study | AMP (Acute Meniscal Pathology) | PURPOSE: Patient-specific instrumentation (PSI) has been proposed as a means of improving surgical accuracy and ease of implantation during technically challenging procedures such as unicompartmental knee arthroplasty (UKA). The purpose of this prospective randomised controlled trial was to compare the accuracy of impl... |
0 | Avoidance of vertebral fractures in men with idiopathic osteoporosis by a three year therapy with calcium and low-dose intermittent monofluorophosphate | Management of Hip Fractures in the Elderly | There are currently no trial-based recommendations for the treatment of idiopathic osteoporosis in men. A prospective, controlled, randomized 3-year study was conducted to evaluate the effects of intermittent, low-dose fluoride combined with continuous calcium supplementation on bone mass and future fracture events in ... |
0 | Repair of the posterior root of the medial meniscus | AMP (Acute Meniscal Pathology) | Tears of the posterior root of the medial meniscus are becoming increasingly recognized. Early identification and treatment of these tears help halt the progression of cartilage degeneration and osteoarthritis of the knee. Repair of these tears is essential for recreating the hoop stress of the medial meniscus. In this... |
0 | Infrapatellar fat pad-derived mesenchymal stromal cells from osteoarthritis patients: In vitro genetic stability and replicative senescence | OAK 3 - Non-arthroplasty tx of OAK | Different sources of mesenchymal stromal cells can be considered for regenerative medicine applications. Here we analyzed human adipose-derived stromal cells from infrapatellar fat pad (IFPSC) of osteoarthritis patients, representing a very interesting candidate for cartilage regeneration. No data are available concern... |
0 | Utilization of Orthobiologics by Sports Medicine Physicians: A Survey-based Study | PRP (Platelet-Rich Plasma) | INTRODUCTION: Investigations are rapidly increasing into products referred to as orthobiologics and their utility in the nonsurgical and surgical treatment of diverse orthopaedic pathology.
METHODS: Members (599) of the American Orthopaedic Society for Sports Medicine were sent a survey that assessed their usage, motiv... |
0 | Risk factors and complications of diabetes: Highlights from the Annual Professional Conference of Diabetes UK, held March 5-7, 2008, in Glasgow, U.K | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Diabetes UK held its annual professional conference on March 5-7, 2008, in Glasgow, U.K. The meeting was devoted to developments in different areas of diabetes, including basic and clinical science, treatment options, risk factors, complications and healthcare delivery and improvement. Copyright 2008 Prous Science, S.A... |
0 | Trends in the Use of Regional Anesthesia: Neuraxial and Peripheral Nerve Blocks | AAHKS (8) Anesthetic Infiltration | BACKGROUND: A growing body of evidence indicates that the use of regional anesthesia offers advantages over general anesthesia, not only in terms of reducing complications but also regarding resource utilization and patient satisfaction. Because of the paucity of data on the nationwide adoption of regional anesthesia t... |
1 | Fascia iliaca compartment block as a preoperative analgesic in elderly patients with hip fractures - effects on cognition | Hip Fx in the Elderly 2019 | BACKGROUND: Impaired cognition is a major risk factor for perioperative delirium. It is essential to provide good pain control in patients with hip fractures and especially important in patients with severely impaired cognitive status, as they receive less pain medication, have poorer mobility, poorer quality of life a... |
0 | Endoscopic techniques in aesthetic plastic surgery | Panniculectomy & Abdominoplasty CPG | There has been an explosive interest in endoscopic techniques by plastic surgeons over the past two years. Procedures such as facial rejuvenation, breast augmentation and abdominoplasty are being performed with endoscopic assistance. Endoscopic operations require a complex setup with components such as video camera, li... |
0 | Overuse injuries in classical ballet | DOD - Acute Comp Syndrome CPG | Successful management of classical ballet dancers with overuse injuries requires an understanding of the art form, precise knowledge of anatomy and awareness of certain conditions. Turnout is the single most fundamental physical attribute in classical ballet and 'forcing turnout' frequently contributes to overuse injur... |
0 | Total elbow arthroplasty for distal humerus fractures | The Treatment of Pediatric Supracondylar Humerus Fractures AUC | Total elbow arthroplasty has become increasingly popular for the treatment of distal humerus fractures in elderly patients with poor bone quality, comminution, and/or pre-existent elbow abnormalities. The procedure is performed without violating the extensor mechanism; the fractured fragments are exposed and resected o... |
0 | Peripheral tears of the triangular fibrocartilage complex cause distal radioulnar joint instability after distal radial fractures | Distal Radius Fractures | The aim of this prospective study was to determine whether peripheral tears of the triangular fibrocartilage complex (TFCC) in patients younger than the osteoporotic age (males,<60 years; females, <50 years) were related to chronic distal radioulnar joint (DRUJ) instability. Fifty-one patients (27 women) with displaced... |
0 | Inside-out meniscus repair | AMP (Acute Meniscal Pathology) | Meniscus repair over resection, when feasible, should be strongly considered in an effort to preserve meniscus integrity and function, especially in younger patients. Currently, a number of techniques and implants may be used to achieve a successful result. Although all-inside meniscus repair devices have evolved signi... |
0 | Can introduction of an uncemented, hydroxyapatite coated hemiarthroplasty for displaced femoral neck fractures be recommended? | Management of Hip Fractures in the Elderly | The role of uncemented fully hydroxyapatite coated hemiarthroplasties for the treatment of displaced femoral neck fractures remains unclear. We investigated if complications, reoperations and mortality differed from that of cemented hemiarthroplasties. The study groups consisted of 78 cemented and 97 uncemented, hydrox... |
0 | Diagnosing amyloidosis: Sensitive tools and alert physicians | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Plasma cell clones can give rise to disorders related to tumor burden, such as multiple myeloma and Waldenstrom macroglobulinemia, as well as to other more subtle and deceptive diseases, such as AL amyloidosis. In this disorder the clone is usually small in size and produces a monoclonal light chain that causes multior... |
1 | Effect of single injection of platelet-rich plasma in comparison with corticosteroid on knee osteoarthritis: a double-blind randomized clinical trial | PRP (Platelet-Rich Plasma) | BACKGROUND: Evidence on the effect of platelet-rich plasma (PRP) in treating osteoarthritis (OA) is insufficient. Therefore, the present study compares the effects of a one-time injection of PRP and corticosteroid (CS).
METHODS: In the present randomized double blind clinical trial, the participants who suffered from k... |
0 | Identification of N-Glycoproteins of Knee Cartilage from Adult Osteoarthritis and Kashin-Beck Disease Based on Quantitative Glycoproteomics, Compared with Normal Control Cartilage | AMP (Acute Meniscal Pathology) | Glycoproteins are involved in the development of many diseases, while the type and content of N-glycoproteins in the cartilage of osteoarthritis (OA) and Kashin–Beck disease (KBD) are still unclear. This research aims to identify N-glycoproteins in knee cartilage patients with OA and KBD compared with normal control (N... |
0 | The risks and external effects of diabetic foot ulcer on diabetic patients: A hospital-based survey in Wuhan area, China | DoD SSI (Surgical Site Infections) | Diabetic foot ulcer (DFU) is a common complication observed in diabetic patients and affects diabetic patients in multiple ways. Severe DFU even leads to amputation in many cases. Early detection and intervention of DFU in diabetic patients can significantly relieve the pain caused by the ulcer and also keep patients f... |
0 | Revision Meniscal Allograft Transplantation in the Lateral Compartment: Disparate MRI and Clinical Outcomes During the Early Postoperative Period | AMP (Acute Meniscal Pathology) | BACKGROUND: Little is known about clinical outcomes after revision meniscal allograft transplantation (RMAT), and there are no studies on magnetic resonance imaging (MRI) evaluations during the early remodeling period.
HYPOTHESIS: The objective imaging results, as determined by MRI evaluation, would be inferior to thos... |
0 | Phase-contrast enhanced synchrotron micro-tomography of human meniscus tissue | AMP (Acute Meniscal Pathology) | OBJECTIVE: To investigate the feasibility of synchrotron radiation-based phase contrast enhanced micro-computed tomography (SR-PhC-muCT) for imaging of human meniscus. Quantitative parameters related to fiber orientation and crimping were evaluated as potential markers of tissue degeneration.
DESIGN: Human meniscus spe... |
0 | Median and ulnar nerve transections treated with microsurgical interfascicular cable grafting with autogenous sural nerve | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Interfascicular nerve grafting was used in 37 median and 26 ulnar nerves, all completely transected. In a follow-up period of 2.5 5 years, useful motor recovery (M3 or higher) was ahieved in 84% of median nerve lesions; in ulnar lesions, useful motor recovery (M2+ or higher) was achieved in 73%. Sensory recovery with s... |
1 | Polytrauma and High-energy Injury Mechanisms Are Associated with Worse Patient-reported Outcomes After Distal Radius Fractures | Distal Radius Fractures | BACKGROUND: Patient-reported outcomes (PROs) are increasingly relevant when evaluating the treatment of orthopaedic injuries. Little is known about how PROs may vary in the setting of polytrauma or secondary to high-energy injury mechanisms, even for common injuries such as distal radius fractures.
QUESTIONS/PURPOSES: ... |
0 | Comparison of mental health between individuals with spinal cord injury and able-bodied controls in Neiva, Colombia | DoD PRF (Psychosocial RF) | Although research has investigated the mental health of individuals with spinal cord injury (SCI), an overwhelming majority of this research has been conducted in the United States, Western Europe, and other developed countries. The purpose of this study was to compare the mental health of individuals with SCI with abl... |
0 | Gait analysis in patients with a preformed articulated knee spacer | PJI DX Updated Search | Two-stage revision is one of the most widely accepted procedures to eradicate infection and restore function in infected knee prosthesis; while the use of an articulated spacers is advocated by many as a means to preserve function between stages, no data are available regarding gait parameters after spacer implant. The... |
0 | Ipsilateral supracondylar humerus fracture and Monteggia lesion: A case report | Distal Radius Fractures | Two to 13% of supracondylar humerus fractures in children are associated with an ipsilateral forearm fracture, most of which are distal radius fractures. We present an unusual case of a 2-year-old girl with an ipsilateral supracondylar humerus fracture and a Monteggia lesion. Our management consisted of percutaneous K-... |
0 | The results of the titanium-coated RM acetabular component at 20 years: A long-term follow-up of an uncemented primary total hip replacement | Management of Hip Fractures in the Elderly | In a prospective study, 93 unselected consecutive uncemented hip arthroplasties were performed in 80 patients using the titanium-coated RM acetabular component and the CLS femoral component. The mean age of the patients at operation was 52 years (28 to 81). None were lost to follow-up. In the 23 patients who had died (... |
0 | Are postoperative complications more common with single-stage bilateral (SBTKR) than with unilateral knee arthroplasty: guidelines for patients scheduled for SBTKR | Surgical Management of Osteoarthritis of the Knee CPG | A significant number of patients with degenerative arthritis of the knee require bilateral knee arthroplasty. Single-stage bilateral total knee arthroplasty (SBTKR) has been associated with increased patient morbidity and mortality. At our institution, the following steps have been taken to minimize the risks to patien... |
1 | Sensory-motor index is useful parameter in electroneurographical diagnosis of carpal tunnel syndrome | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | It was performed electroneurographic (ENG) studies with surface electrodes and examined nervus medianus (NM) in 60 patients (38 females), average age of 50,28 years (X+/-SD=50,28+/-11), with clinical diagnosis of carpal tunnel syndrome (CTS) and at least one border or discrete abnormal value of conventional electrophys... |
0 | Comparison of volumetric bone mineral density in the operated and contralateral knee after anterior cruciate ligament and reconstruction: A 1-year follow-up study using peripheral quantitative computed tomography | OAK 3 - Non-arthroplasty tx of OAK | The purpose of this study was to quantify changes in volumetric bone mineral density (vBMD) in the tibial plateau of the operated and contralateral leg measured using peripheral quantitative computed tomography (pQCT) before and 3, 6, and 12 months after anterior cruciate ligament (ACL) reconstruction. The ACL was reco... |
0 | Hemiosteoporosis after severe stroke, independent of changes in body composition and weight | Management of Hip Fractures in the Elderly | BACKGROUND AND PURPOSE: Fractures are a serious complication after stroke, and the risk of hip fractures among stroke patients is increased 2 to 4 times versus a reference population. Fractures after stroke are probably caused by the development of hemiosteoporosis and the high incidence of accidental falls. The aim of... |
0 | Male-female differences in the association between incident hip fracture and proximal femoral strength: A finite element analysis study | Management of Hip Fractures in the Elderly | Hip fracture risk is usually evaluated using dual energy X-ray absorptiometry (DXA) or quantitative computed tomography (QCT) which provide surrogate measures for proximal femoral strength. However, proximal femoral strength can best be estimated explicitly by combining QCT with finite element (FE) analysis. To evaluat... |
0 | Preliminary findings on biomarker levels from extracerebral sources in patients undergoing trauma surgery: Potential implications for TBI outcome studies | Hip Fx in the Elderly 2019 | Background: Despite several experimental studies on the role of S100B and NSE in fractures, no studies on the influence of surgery on the biomarker serum levels have been performed yet. Methods: The serum levels of S100B and NSE were analysed in patients with fractures that were located in the spine (group 1, n = 35) o... |
0 | Epidemiology of fractures in England and Wales | Management of Hip Fractures in the Elderly | Records from the General Practice Research Database were used to derive age- and gender-specific fracture incidence rates for England and Wales during the period 1988-1998. In total, 103,052 men and 119,317 women in the sample of 5 million adults sustained a fracture over 10.4 million and 11.2 million person-years (py)... |
0 | Results of the Latarjet coracoid bone block procedure performed by mini invasive approach | Glenohumeral Joint OA | Introduction: The coracoid block technique described by Latarjet was modified by Patte and Walch in order to increase the glenoid surface. Saragaglia further modified this technique and described a minimally invasive approach which allows faster post-operative recovery. The aim of this study was to evaluate the medium-... |
0 | The essential features of microorganisms and the rationale for antimicrobial therapy | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Antimicrobial agents have had a major impact on the control of most bacterial diseases; however, viral, fungal, protozoal and helminthic diseases have generally been less amenable to drug therapy. The reason for this lies in the different structural and physiological features that each group of microorganisms have. Thi... |
0 | Women's experiences of postnatal distress: a qualitative study | DoD PRF (Psychosocial RF) | BACKGROUND: Women can experience a range of psychological problems after birth, including anxiety, depression and adjustment disorders. However, research has predominantly focused on depression. Qualitative work on women's experiences of postnatal mental health problems has sampled women within particular diagnostic ca... |
0 | In vivo measurement of localized tibiofemoral cartilage strains in response to dynamic activity | AMP (Acute Meniscal Pathology) | BACKGROUND: Altered local mechanical loading may disrupt normal cartilage homeostasis and play a role in the progression of osteoarthritis. Currently, there are limited data quantifying local cartilage strains in response to dynamic activity in normal or injured knees.
PURPOSE/HYPOTHESIS: To directly measure local tibi... |
0 | Practice considerations for proton beam radiotherapy of uveal melanoma during the COVID-19 pandemic: PTCOG Ocular experience | Coronavirus Disease 2019 (COVID-19) | Uveal melanoma (UM) is a rare but life-threatening cancer of the eye. In light of the COVID-19 pandemic, hospitals and proton eye therapy facilities must analyze several factors to ensure appropriate treatment protocols for patients and provider teams. Practice considerations to limit COVID-19 transmission in the proto... |
0 | Reduction of post-traumatic swelling and compartment pressure by impulse compression of the foot | DOD - Acute Comp Syndrome CPG | Following the discovery of a powerful venous pump in the foot that is activated by weight-bearing independently of muscular action, a pneumatic impulse device was developed to actuate this pump artificially. In a multicentre international trial the device was shown to reduce post-traumatic and postoperative swelling; p... |
0 | Osteoarthritis of the knee | OAK 3 - Non-arthroplasty tx of OAK | As of mid-2016, there is still no evidence that hyaluronic acid is more effective than placebo in osteoarthritis of the knee. It does however have adverse effects. |
0 | Malignant Spinal Cord Compression: Adapting Conventional Rehabilitation Approaches | MSTS 2018 - Femur Mets and MM | Spinal tumors are classically grouped into 3 categories: extradural, intradural extramedullary, and intradural intramedullary. Spinal tumors may cause spinal cord compression and vascular compromise resulting in pain or neurologic compromise. They may also alter the architecture of the spinal column, resulting in spina... |
0 | Aseptic meningitis associated with cephalosporins in an infant with trisomy 21 | Patrick’s pharmacoepidemiology project | The authors report a case of aseptic meningitis associated with cephalosporins in an infant. A 1-year-old boy with trisomy 21 received several antimicrobials including cefotaxime and ceftriaxone for bacterial meningitis caused by Haemophilus influenzae b. High fever continued for more than a month, and discontinuation ... |
0 | Emerging anti-cancer molecular mechanisms of aminobisphosphonates | MSTS 2018 - Femur Mets and MM | Bone metastases are common in patients with many types of cancer, especially breast and prostate cancer - in which the incidence is approximately 70% among patients with advanced metastatic disease. Aminobisphosphonates (NBPs) have entered clinical practice in the treatment of bone metastases from several neoplasms, in... |
0 | Fixed bearing lateral unicompartmental knee arthroplasty--short to midterm survivorship and knee scores for 101 prostheses | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Isolated unicompartmental knee arthritis is less common laterally than medially. Lateral unicompartmental knee arthroplasty (UKA) constitutes only 1% of all knee arthroplasty performed. Use of medial UKA is supported by several published series showing good long-term survivorship and patient satisfaction, i... |
0 | Longitudinal Change in Knee Cartilage Thickness and Function in Subjects with and without MRI-Diagnosed Cartilage Damage | AMP (Acute Meniscal Pathology) | Objective: Cartilage damage diagnosed by magnetic resonance imaging (MRI) is highly prevalent in the population. In this article, we explore whether such cartilage damage is associated with greater longitudinal change in 3D cartilage thickness and knee function in subjects without (risk factors of) knee osteoarthritis.... |
1 | Popliteal artery repair in massively transfused military trauma casualties: a pursuit to save life and limb | DoD SSI (Surgical Site Infections) | BACKGROUND: Popliteal artery war wounds can bleed severely and historically have high rates of amputation associated with ligation (72%) and repair (32%). More than before, casualties are now surviving the initial medical evacuation and presenting with severely injured limbs that prompt immediate limb salvage decisions... |
0 | Variations in treatment of postmenopausal osteoporosis | Management of Hip Fractures in the Elderly | The purpose of this study was to determine trends and differences between various medical specialties with regard to the treatment of postmenopausal osteoporosis. The method used was a cross-sectional survey, and the authors' sample was composed of 116 physicians. There was an overall lack of consensus on choice of tre... |
0 | Late follow-up of femoral head avascular necrosis managed by intertrochanteric osteotomy & bone grafting | AAHKS (2) Corticosteroids | A prospective study was carried out on fifty hips in forty-eight patients with Ficat stage III (Steinberg stage IV) avascular necrosis (head deformity evident on plain x-ray) involving the supero-ventral segment. Mean age was 33 +/- 8 years (mean and standard deviation). There were thirty-six male and twelve female pat... |
0 | Modular prosthesis reconstruction after tumour resection, evaluation of failures and survival | MSTS 2022 - Metastatic Disease of the Humerus | OBJECTIVE: To analyze a series of patients with bone tumours reconstructed with modular prostheses and to evaluate: 1) Survival of the implant. 2) Causes of failure. 3) Complication rates. 4) Limb salvage overall survival. 5) Functional results and full weight bearing.
MATERIALS AND METHODS: A retrospective study from ... |
0 | Effects of ultrasound guidance on the minimum effective anaesthetic volume required to block the femoral nerve | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: We tested the hypothesis that ultrasound guidance may reduce the minimum effective anaesthetic volume (MEAV50) of ropivacaine 0.5% required to block the femoral nerve compared with nerve stimulation guidance. METHODS: After standard premedication and sciatic nerve block were given, 60 patients undergoing kn... |
0 | Platelet-derived growth factor-coated decellularized meniscus scaffold for integrative healing of meniscus tears | OAK 3 - Non-arthroplasty tx of OAK | The aim of this study was to examine the potential of platelet-derived growth factor (PDGF)-coated decellularized meniscus scaffold in mediating integrative healing of meniscus tears by inducing endogenous cell migration. Fresh bovine meniscus was chemically decellularized and covalently conjugated with heparin and PDG... |
0 | A Unique Failure Mechanism of a Constrained Total Hip Arthroplasty. A Brief Review of the Literature | Management of Hip Fractures in the Elderly | Constrained acetabular systems are successful in achieving stability in patients with recurrent dislocations, abductor deficiency, or where a source of instability cannot be determined. We report on one patient with 2 dissociations of a tripolar constrained acetabular liner caused by impingement when the patient exceed... |
0 | Low-frequency sonication may alter surface topography of endoprosthetic components and damage articular cartilage without eradicating biofilms completely | PJI DX Updated Search | Two-stage exchange arthroplasty is the current standard of care for arthroplasty-related infections. Reinfection rates up to 30% are reported, and there is significant morbidity for the patient. In cases of failure, arthrodesis or amputation may result. Ultrasonic treatment has the potential to eradicate biofilms and a... |
0 | Hydrogels for precision meniscus tissue engineering: a comprehensive review | AMP (Acute Meniscal Pathology) | The meniscus plays a pivotal role to preserve the knee joint homeostasis. Lesions to the meniscus are frequent, have a reduced ability to heal, and may induce tibiofemoral osteoarthritis. Current reconstructive therapeutic options mainly focus on the treatment of lesions in the peripheral vascularized region. In contra... |
0 | Allograft reconstruction of segmental defects of the humeral head associated with posterior dislocations of the shoulder | Glenohumeral Joint OA | Six men underwent operative management of defects of the humeral head involving at least 40% of the articular surface, following posterior dislocation of the humeral head. The cause of dislocation was a grand mal seizure in three and a fall in three cases. In five cases the dislocation was reduced under general anaesth... |
0 | Distal humeral fractures: impact of lateral approach and fracture-specific plating on radial nerve palsies | Distal Radius Fractures | We retrospectively reviewed supracondylar distal humeral fractures that had been treated with fracture-specific plating and definitive fixation through a lateral approach with a medial triceps mobilization technique. We determined the incidences of preoperative and postoperative radial nerve palsies (RNP) to evaluate t... |
0 | CXCL12 genetic variants as prognostic markers in nasopharyngeal carcinoma | MSTS 2018 - Femur Mets and MM | The chemokine receptor 4/chemokine ligand 12 (CXCR4/CXCL12) axis plays an important role in tumorigenesis, metastasis, and recurrence of tumors. Its single nucleotide polymorphisms (SNPs) are associated with patient survival in several types of cancer. However, the prognostic value of SNPs in nasopharyngeal carcinoma (... |
0 | Preventing osteoporosis in every day life | Management of Hip Fractures in the Elderly | Osteoporosis is a condition characterized by low bone mineral density, microarchitectural deterioration of bone tissue, and a consequent increase in fracture risk. The public health impact of osteoporosis stems from its association with fractures of the hip, spine and forearm. Between 10 and 20 percent of hip fracture ... |
0 | Monoclonal gammopathy of undetermined significance: why identification of these patients and assessment of their skeletons is important | MSTS 2018 - Femur Mets and MM | Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder characterized by the presence of a serum monoclonal immunoglobulin (M-protein) at <or= 3 g/dL. It is an asymptomatic premalignant disorder that can progress to multiple myeloma and related B-cell disorders. Recent studies have suggested... |
0 | Does a Triple-Wedge, Broach-Only Stem Design Reduce Early Postoperative Fracture in Anterior Total Hip Arthroplasty? | Hip Fx in the Elderly 2019 | INTRODUCTION: The direct anterior (DA) approach for total hip arthroplasty (THA) is gaining popularity; however, this approach still poses a higher risk for femoral complications, including fracture. The design of cementless stems can also impact the risk of fracture. The purpose of this study is to evaluate the early ... |
1 | A preliminary evaluation of the motivational model of pain self-management in persons with spinal cord injury-related pain | DoD PRF (Psychosocial RF) | UNLABELLED: Chronic pain commonly accompanies long-term disabilities such as spinal cord injury (SCI). Research suggests that patient motivation to engage in adaptive pain coping strategies, such as exercise/stretching and task persistence, is an important factor in determining the impact that this pain will have on qu... |
0 | Aging and sequelae of poliomyelitis | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Objective: We estimate that there are about 50,000 persons who survived poliomyelitis in their childhood in France (mean age estimated between 50 and 65 years). After a few decades of stability, 30 to 65% of individuals who had been infected and recovered from polio begin to experience new signs and symptoms. Method: R... |
1 | A meta-analysis of etidronate for the treatment of postmenopausal osteoporosis | Management of Hip Fractures in the Elderly | The aim of the study was to review the effect of etidronate on bone density and fractures in postmenopausal women. We searched MEDLINE from 1966 to 1998, examined citations of relevant articles, and the proceedings of international osteoporosis meetings. We contacted osteoporosis investigators to identify additional st... |
0 | Risk factors for hip fractures occurring in the hospital | Management of Hip Fractures in the Elderly | Risk factors for in-hospital hip fractures among patients aged > or = 65 years were evaluated in a population-based case-control study conducted in the Canadian province of Saskatchewan from 1983 through 1985. There were 129 cases with confirmed in-hospital hip fractures and 234 controls, who were those controls from a... |
0 | Type D personality is independently associated with major psychosocial stressors and increased health care utilization in the general population | DoD PRF (Psychosocial RF) | BACKGROUND: Type D is considered as a non pathological personality trait and propensity for mental distress. Its relationship with mental distress has been mainly studied in cardiovascular patients and with respect to depression. The knowledge about the relationship of Type D with mental disorders, psychosocial stresso... |
0 | Quantitative measurement of cartilage volume with automatic cartilage segmentation in knee osteoarthritis | AMP (Acute Meniscal Pathology) | Purpose: To determine the reproducibility of the automatic cartilage segmentation method using a prototype KneeCaP software (version 1.3; Siemens Healthcare, Erlangen, Germany) and to compare the difference in cartilage volume (CV) between the normal knee joint and knee osteoarthritis (KOA) of different degrees by usin... |
0 | "Long-term stability of stimulating spiral nerve cuff electrodes on human peripheral nerves" | DoD LSA (Limb Salvage vs Amputation) | BACKGROUND: Electrical stimulation of the peripheral nerves has been shown to be effective in restoring sensory and motor functions in the lower and upper extremities. This neural stimulation can be applied via non-penetrating spiral nerve cuff electrodes, though minimal information has been published regarding their l... |
0 | Experience and technical refinements in the "donut" mastopexy with augmentation mammaplasty | Reduction Mammoplasty for Female Breast Hypertrophy | Minor ptosis and pseudoptosis of the breast may be corrected by a "donut" mastopexy. This technique offers the opportunity to reach a good aesthetic result with minimal scarring. A prosthesis is inserted at the time of the mastopexy and the skin is reduced in an elliptical way to achieve a good balance between the brea... |
0 | Has orthopaedic intervention for rheumatoid arthritis changed in line with combination and anti-TNF therapies? an evaluation of joint surgery rates and prognostic factors in two UK inception cohorts (1986-2011) | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Background: Orthopaedic surgery in RA is considered a surrogate marker for joint destruction. It has been postulated that the need for orthopaedic surgery would be reduced with greater use of more intense therapies for RA. We were able to examine this proposal in two UK multicentre inception cohorts conducted between 1... |
0 | The effect of bone quality on the outcome of ingrowth total knee arthroplasty | Surgical Management of Osteoarthritis of the Knee CPG | Bone quality generally is felt to be an important consideration when planning total knee arthroplasty (TKA). This prospective study was conducted to see if bone quality, as assessed intraoperatively in 346 knees, affects the outcome of ingrowth TKA. Group A consisted of 272 knees with good or excellent bone quality in ... |
0 | Decisions on drug therapies by numbers needed to treat: a randomized trial | Management of Hip Fractures in the Elderly | BACKGROUND: The number needed to treat (NNT) has been promoted as the preferred effect measure when patients and physicians share decision making. Our aim was to explore the impact of the NNT on laypeople's decisions about preventive drug therapies. METHODS: Two thousand subjects were selected for the survey; 1201 (60%... |
0 | Small-dose intrathecal clonidine and isobaric bupivacaine for orthopedic surgery: a dose-response study | AAHKS (8) Anesthetic Infiltration | We examined the dose-response relationship of intrathecal clonidine at small doses (<or=150 microg) with respect to prolonging bupivacaine spinal anesthesia. We aimed for establishing doses of intrathecal clonidine that would produce clinically relevant prolongation of spinal anesthesia and pain relief without signific... |
1 | Osteoporosis and shoulder osteoarthritis: incidence, risk factors, and surgical implications | Glenohumeral Joint OA | BACKGROUND: Patients with osteoarthritis undergoing shoulder arthroplasty may suffer from osteoporosis. The purpose of this study was to determine whether computed tomography (CT)-derived Hounsfield unit (HU) measurements correlate with bone mineral density (BMD) and whether these data could predict implant size and fi... |
0 | Parental stress and burden following traumatic brain injury amongst children and adolescents | DoD PRF (Psychosocial RF) | PRIMARY OBJECTIVES: To assess parental stress following paediatric traumatic brain injury (TBI), and examine the relationship between self-reported problems, parental stress and general health.
RESEARCH DESIGN: Parents of 97 children admitted with a TBI (49 mild, 19 moderate, 29 severe) to North Staffordshire National ... |
0 | Gait and clinical improvements with a novel knee brace for knee OA | OAK 3 - Non-arthroplasty tx of OAK | INTRODUCTION: Knee osteoarthritis causes debilitating pain, and results in characteristic gait changes. Some authors believe that a system of neuromuscular retraining may improve these parameters. We therefore evaluated a novel brace that combines pneumatic joint unloading and active swing-assist to assess: (1) differe... |
0 | Pediatric trauma beyond the brain | DOD - Acute Comp Syndrome CPG | In pediatric trauma care, many long-held tenets of management have been revised. This article reviews the latest advances in pediatric trauma care, particularly in the areas of resuscitation and management of thoracic and abdominal injuries. The final topic is a discussion of what the intensivist and surgeon must know ... |
0 | A review of transfusion risks and optimal management of perioperative bleeding with cardiac surgery | Coronavirus Disease 2019 (COVID-19) | Although the incidence and pathophysiology of many transfusion-related complications are well documented, unresolved questions persist. Transfusion medicine initiatives are being implemented to reduce complications (e.g., chemical inactivation of pathogens, WBC depletion); however, the literature is describing an incre... |
0 | Skeletal disorders in children with renal failure | Diagnosis and Treatment of Osteochondritis Dissecans AUC | There are relatively few reports concerning management of the musculoskeletal problems of children with renal failure. From a population group of 124 children with renal failure treated at The Children's Hospital, Camperdown, 16 were referred for management of skeletal problems. These problems included genu valgum, sli... |
0 | Body mass index as a predictor of fracture risk: a meta-analysis | Management of Hip Fractures in the Elderly | Low body mass index (BMI) is a well-documented risk factor for future fracture. The aim of this study was to quantify this effect and to explore the association of BMI with fracture risk in relation to age, gender and bone mineral density (BMD) from an international perspective using worldwide data. We studied individu... |
0 | Bilateral carpal tunnel syndrome in an adolescent | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | A 13-year-old boy with nocturnal paresthesias of the hands was shown to have bilateral carpal tunnel syndrome by electrodiagnosis. Surgical findings included thickening of the transverse carpal ligament and local anomalies of tendon and muscle. Surgical correction produced prompt relief |
0 | Influence of age and body weight on spine and femur bone mineral density in U.S. white men | Management of Hip Fractures in the Elderly | Bone mineral density (BMD) was measured in normal white males using 153 Gd dual-photon absorptiometry. Measurements were made on the lumbar spine (n = 315) and on the proximal femur (n = 282) utilizing three regions of interest. There was a small but significant age-related decrease in spinal BMD (r = -0.11; -0.001 g/c... |
0 | Biomechanical Osteoarthritis Outcomes in Meniscectomy Patients | OAK 3 - Non-arthroplasty tx of OAK | The key aim of this study is to examine biomechanical measures associated with osteoarthritis (OA) progression in patients who have lateral and medial menisci injuries during various tasks. The likelihood is that individuals who have a meniscal injury often develop knee osteoarthritis. Therefore understanding biomechan... |
0 | The operative management of osteoporotic fractures of the knee: to fix or replace? | Surgical Management of Osteoarthritis of the Knee CPG | This review considers the surgical treatment of displaced fractures involving the knee in elderly, osteoporotic patients. The goals of treatment include pain control, early mobilisation, avoidance of complications and minimising the need for further surgery. Open reduction and internal fixation (ORIF) frequently result... |
0 | The National Register of Joint Replacements of the Czech Republic | PJI DX Updated Search | The National Register of Joint Replacements of the Czech Republic was established as part of the National Health Information System in 2002. The register's administrator is the Institute of Health Information and Statistics of the Czech Republic, the Czech Society for Orthopaedics and Traumatology acts as its guarantor... |
0 | The most important frequently asked questions of patients with hip or knee osteoarthritis: a best-worst scaling exercise | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: The aim of this study was to collect and prioritize which questions (FAQs) patients with hip or knee osteoarthritis and healthcare professionals consider to be the most important to be answered, in order to identify informational needs that go beyond guideline recommendations.
METHODS: The following steps we... |
0 | Noncemented Total Hip Arthroplasty in Sickle-Cell Disease: Long-Term Results | DoD SSI (Surgical Site Infections) | Background: Avascular necrosis of the femoral head is a well-known sequela of sickle-cell disease (SCD) requiring a surgical intervention that comes with technical challenges. Methods: Uncemented hip arthroplasty for avascular necrosis of the femoral head due to SCD was carried out for 101 patients (133 hips) between 2... |
0 | Outcome of allogeneic hematopoietic cell transplantation from HLA-identical siblings for severe aplastic anemia in patients over 40 years of age | Reconstruction After Skin Cancer | Patients with severe aplastic anemia (SAA) over 40 years of age are often not offered treatment with hematopoietic cell transplantation (HCT) because of concerns about treatment-related morbidity or mortality. To evaluate this risk, we analyzed outcomes after allogeneic HCT from HLA-identical sibling donors for all old... |
0 | Low incidence of calcium pyrophosphate dihydrate crystal deposition in rheumatoid arthritis, with modification of radiographic features in coexistent disease | AMP (Acute Meniscal Pathology) | A negative correlation between rheumatoid arthritis (RA) and calcium pyrophosphate dihydrate (CPPD) crystal deposition was demonstrated in separate controlled radiographic and synovial fluid surveys of RA patients aged 55-75 years. Knee chondrocalcinosis was detected in 14% of 135 normal controls and 28% of 87 post-men... |
0 | Effect of hypoxia/reoxygenation on the cytokine-induced production of nitric oxide and superoxide anion in cultured osteoarthritic synoviocytes | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Hypoxia/reoxygenation (H/R) is an important feature in the osteoarthritis (OA) physiopathology. Nitric oxide (NO) is a significant proinflammatory mediator in the inflamed synovium. The purpose of this study was to investigate the effects of H/R on inducible NO synthase (iNOS) activity and expression in OA s... |
0 | Future directions in regional treatment strategies for melanoma and sarcoma | Reconstruction After Skin Cancer | Hyperthermic isolated limb perfusion (HILP) with melphalan and more recently isolated limb infusion (ILI) with melphalan +/- dactinomycin are common treatment modalities for both in-transit melanoma of the extremity and advanced extremity sarcoma. In order to further optimize treatment, future research should focus on ... |
0 | Should Kirschner wires for fixation of lateral humeral condyle fractures in children be buried or left exposed? A systematic review | DoD SSI (Surgical Site Infections) | BACKGROUND: Displaced lateral humeral condyle fractures in children are usually treated with open reduction and internal fixation. When treated operatively with Kirschner wires, the bent cut near side wire ends are either buried in the subcutaneous tissue or are left exposed. It is believed that burying the wires allow... |
0 | Evaluating Anterior Knee Pain | Osteochondritis Dissecans 2020 Review | Musculoskeletal complaints account for about 20% to 30% of all primary care office visits; of these visits, discomfort in the knee, shoulder, and back are the most prevalent musculoskeletal symptoms. Having pain or dysfunction in the front part of the knee is a common presentation and reason for a patient to see a heal... |
1 | Noncontiguous and open fractures of the lower extremity: Epidemiology, complications, and unplanned procedures | DoD SSI (Surgical Site Infections) | INTRODUCTION: Isolated fractures of the lower extremity are relatively common injuries while multifocal injuries resulting from high-energy trauma are less frequently encountered. Our objectives are to characterise patients who sustained multiple noncontiguous fractures and open fractures of the lower extremity, report... |
0 | Prospective study on harvesting autologous bone grafts from the anterior iliac crest using a new specialized reamer | DoD SSI (Surgical Site Infections) | The iliac crest remains the most frequent donor site for bone harvesting. Despite the surgical access to the iliac crest being relatively simple and the operation being carried out regularly, there are frequent complications. Therefore, a new, manual iliac crest reamer (R group) was compared to the classical harvesting... |
0 | Changing incidence of orthopedic surgery in rheumatic disease: Contributing factors topical collection on surgery and perioperative care | AMP (Acute Meniscal Pathology) | Rheumatic diseases are multisystem conditions that predominantly affect the musculoskeletal system, leading to soft tissue and articular damage. Historically, medical therapy was able to slow, but not prevent, erosion and joint destruction, resulting in the frequent need for orthopedic procedures to maintain function a... |
0 | Induction of prolactin expression and release in human preadipocytes by cAMP activating ligands | Reduction Mammoplasty for Female Breast Hypertrophy | In addition to the pituitary, prolactin (PRL) in humans is produced at non-pituitary sites where it acts as a cytokine. We previously reported that PRL is expressed and released from breast adipose explants, raising the question as to the dynamics of its production and its regulation. Preadipocytes were isolated from b... |
0 | Distribution of Porphyromonas gingivalis fimA genotypes in cardiovascular specimens from Japanese patients | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | INTRODUCTION: Porphyromonas gingivalis, a major periodontal pathogen, is gaining increasing attention for its possible association with cardiovascular diseases. Its fimbriae are classified into six genotypes (types I-V and Ib) based on the diversity of the fimA genes encoding the fimbrial subunits. In this study, fimA ... |
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