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Effect of two different preparations of platelet-rich plasma on synoviocytes
PRP (Platelet-Rich Plasma)
PURPOSE: To analyse the modifications induced by two different platelet-rich plasma (PRP) preparations on osteoarthritis (OA) synoviocytes, by documenting changes in gene expression of factors involved in joint physiopathology. METHODS: OA synoviocytes were cultured for 7 days in medium with different concentrations of...
1
Assessment and prediction of stress-related growth
DoD PRF (Psychosocial RF)
This article reports the development of the Stress-Related Growth Scale (SRGS) and its use in a study examining determinants of stress-related positive outcomes for college students. Study 1 analyses showed that the SRGS has acceptable internal and test-retest reliability and that scores are not influenced by social de...
0
Antegrade nailing can prevent cubitus varus and valgus after pediatric supracondylar fractures with impacted columns
Pediatric Supracondylar Humerus Fracture 2020 Review
Supracondylar fractures are commonly encountered in the pediatric population. An impacted radial or ulnar column may result in the deviation of the elbow axis in the frontal plane clinically seen as cubitus varus or valgus. Antegrade nailing has become a feasible alternative to treat supracondylar fractures. It is not ...
0
Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement
Surgical Management of Osteoarthritis of the Knee CPG
Purpose: The presence of bone marrow lesions (BMLs) have been linked to pain and progression of disease in knee osteoarthritis (OA). This study aims to determine the relationship between bone marrow lesions (BMLs) and cartilage volume at baseline, cartilage volume loss over 2 years, and risk of knee joint replacement o...
0
Measurement the prevalence of osteoarthritis of knee joint in urban
OAK 3 - Non-arthroplasty tx of OAK
In women there is an increased prevalence of knee and hand joint osteoarthritis while men have a high prevalence of hip osteoarthritis. However hip osteoarthritis is comparatively uncommon in India. Joint weakness and joint loading are the two main contributing factors for development of osteoarthritis.Age is the most ...
0
Physical activity levels and quality of life relate to collagen turnover and inflammation changes after running
OAK 3 - Non-arthroplasty tx of OAK
The purpose of this study was to determine whether an association existed between self-reported symptom and function scores and tissue turnover or inflammatory biomarker changes after a running bout among individuals with and without an acute knee-injury history. A pre-test/post-test prospective cohort study design (Le...
0
Minocycline in rheumatoid arthritis. A 48-week, double-blind, placebo-controlled trial. MIRA Trial Group
Management of Hip Fractures in the Elderly
OBJECTIVE: To assess the safety and efficacy of minocycline in the treatment of rheumatoid arthritis.DESIGN: A double-blind, randomized, multicenter, 48-week trial of oral minocycline (200 mg/d) or placebo.SETTING: 6 clinical centers in the United States.PATIENTS: 219 adults with active rheumatoid arthritis who had pre...
0
Exercise-induced Hypoalgesia in People With Knee Osteoarthritis With Normal and Abnormal Conditioned Pain Modulation
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVES: Normal efficiency of exercise-induced hypoalgesia (EIH) has been demonstrated in people with knee osteoarthritis (OA), while recent evidence suggests that EIH may be associated with features of pain sensitization such as abnormal conditioned pain modulation (CPM). The aim of this study was to investigate wh...
0
Surgical site infections linked to contaminated surgical instruments
DoD SSI (Surgical Site Infections)
Background: This study describes an investigation into a sudden increase in surgical site infection rate following 'clean' surgery. The outbreak involved 15 orthopaedic patients following metal insertion, and five ophthalmology patients who developed endophthalmitis. Aim: An outbreak committee was convened in order to ...
0
Osteoarthritis of the knee joint: An overview
Surgical Management of Osteoarthritis of the Knee CPG
Knee osteoarthritis (OA) is a disorder of cartilage and periarticular bone. It is a most frequent chronic musculoskeletal disorder and the leading cause of disability in the elderly. The risk factors include genetics, female sex, past trauma, advancing age, and obesity. A plain radiograph may help in the diagnosis of k...
0
Clinical outcomes of 168 Chinese patients after local surgery for bone metastases arising from advanced renal cell carcinoma
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: The effectiveness of local surgery for bone metastases (BM) arising from renal cell carcinoma (RCC) remains uncertain. Herein, the authors performed what to the best of their knowledge is the first investigation of the outcomes of Chinese patients with RCC and BM. METHODS: Data were collected for 168 patien...
0
Nodular cutaneous amyloidosis and carpal tunnel syndrome due to the amyloidogenic transthyretin His 114 variant
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
This is the second report of transthyretin (TTR) amyloidosis in a patient who had ATTR Tyr114His diagnosed by mass spectrometry and gene analysis. This case had some clinical features that differed from those of the first reported cases. The patient, 73-year-old man, complained of generalized cutaneous tubercula that h...
1
Vitamin D and intact PTH status in patients with hip fracture
Management of Hip Fractures in the Elderly
INTRODUCTION: The prevalence of hypovitaminosis D in patients with acute hip fracture was examined in a population on Sado Island in Japan. There were 85 cases of hip fracture among this population in 2004, giving an overall incidence of hip fracture of 121.4 per 100,000 population per year. This study included 50 of t...
1
Biological augmentation and tissue engineering approaches in meniscus surgery
AMP (Acute Meniscal Pathology)
PURPOSE: The purpose of this review was to evaluate the role of biological augmentation and tissue engineering strategies in meniscus surgery. Although clinical (human), preclinical (animal), and in vitro tissue engineering studies are included here, we have placed additional focus on addressing preclinical and clinica...
1
Implementation of an electronic care pathway for hip fracture patients: a pilot before and after study
Hip Fx in the Elderly 2019
BACKGROUND: Care pathways are generally paper-based and can cause communication failures between multidisciplinary teams, potentially compromising the safety of the patient. Computerized care pathways may facilitate better communication between clinical teams. This study aimed to investigate whether an electronic care ...
0
Evaluation of finger blood flow with Tc-99m MDP (methylene diphosphonate)
MSTS 2018 - Femur Mets and MM
BACKGROUND: A variety of methods were used to establish objective diagnostic criteria of Raynaud's phenomenon. We intended to introduce another method, using radionuclide (Tc-99m methylene diphosphonate) scintigraphy, which is more objective, simple and economical than the past methods. METHODS: The finger blood flow w...
0
The vascular supply to the skin: an anatomical and physiological reappraisal--Part II
Reduction Mammoplasty for Female Breast Hypertrophy
The subcutaneous vascular system demonstrated in the first part of this study augments skin flap survival when included within human abdominal flaps. Flaps with larger subcutaneous vessels will survive to a greater length than flaps supplied solely by the subdermal plexus. Knowledge of the subcutaneous vascular system ...
0
Unexpected failure of highly cross-linked polyethylene acetabular liner
Management of Hip Fractures in the Elderly
Highly cross-linked polyethylene (HXPE) in total hip arthroplasty has been shown to decrease wear rate compared with conventional liner. However, it has some disadvantages in that the mechanical properties cause early failure of the implant. This case report presents an unexpected failure of total hip arthroplasty in a...
0
One-step surgery with multipotent stem cells for the treatment of large full-thickness chondral defects of the knee
PJI DX Updated Search
BACKGROUND: Chondral lesions in athletically active patients cause considerable morbidity, and treatment with existing cell-based therapies can be challenging. Bone marrow has been shown as a possible source of multipotent stem cells (MSCs) with chondrogenic potential and is easy to harvest during the same surgical pro...
1
Dorgan's lateral cross-wiring of supracondylar fractures of the humerus in children: A retrospective review
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
INTRODUCTION: The currently accepted treatment for displaced supracondylar humeral fractures in children is closed reduction and fixation with percutaneous Kirschner wires. The purpose of this study was to retrospectively review a novel cross-wiring technique where the cross-wire configuration is achieved solely from t...
0
Nacre extract restores the mineralization capacity of subchondral osteoarthritis osteoblasts
OAK 3 - Non-arthroplasty tx of OAK
Osteoarthritis (OA) is the most common cause of joint chronic pain and involves the entire joints. Subchondral osteoarthritic osteoblasts present a mineralization defect and, to date, only a few molecules (Vitamin D3 and Bone Morphogenetic Protein2) could improve the mineralization potential of this cell type. In this ...
0
Uncemented ceramic-on-ceramic bearing couple for dysplastic osteoarthritis: A 5- to 11-year follow-up study
Management of Hip Fractures in the Elderly
The ceramic-on-ceramic bearing couple (CoC) has a potential to improve the longevity of hip arthroplasty. Dysplastic patients are relatively young and have high activity; therefore, the longevity of the implant is essential for them. Because of the anatomical property, adjusting the alignment of an uncemented implant m...
0
Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production
Hip Fx in the Elderly 2019
Ageing is accompanied by reduced functioning of the immune system, termed immunesenescence which is associated with increased risk of infection and mortality. However the immune system does not operate in isolation and can be modified by many environmental factors, including stress. In this study we determined whether ...
1
Abdominoplasty without Drains or Progressive Tension Suturing
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Over the years, the techniques of performing abdominoplasty have been modified and altered. Some of these modifications include progressive tension suturing and preservation of sub-Scarpa fat. These alterations have been done to decrease the risk of postoperative seroma and hematoma formation. Abdominoplast...
0
Longitudinal Relationship Between Knee Pain Status and Incident Frailty: Data from the Osteoarthritis Initiative
OAK 3 - Non-arthroplasty tx of OAK
Objective: Examine the longitudinal association between knee pain and prefrailty/frailty. Design: Longitudinal study. Setting: Five clinical centers across the United States. Subject: Data from 3,053 nonfrail participants aged 45-79 years at baseline from the Osteoarthritis Initiative. Methods: According to self-report...
0
Perioperative cytokine patterns in CSF and plasma during and after knee replacement surgery
Surgical Management of Osteoarthritis of the Knee CPG
INTRODUCTION: Postoperative Delirium has been associated with worsened functional and cognitive decline, and other adverse sequelae(1-4), in particular in older patients(5). Recent data in animal studies demonstrate increases in inflammatory markers in serum and cerebrospinal fluid (CSF) even after aseptic surgery, sug...
0
Tibial tubercle osteotomy with screw fixation for total knee arthroplasty
PJI DX Updated Search
This study investigated the efficacy of tibial tubercle osteotomy (TTO) with screw fixation as part of the surgical treatment of primary complicated total knee arthroplasty (TKA) and revision TKA. From January 2000 to April 2011, 15 patients (15 knees) underwent revision TKA and 20 patients (21 knees) underwent primary...
0
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery
DoD SSI (Surgical Site Infections)
OBJECTIVES: The primary aim of this study was to assess whether local administration of tranexamic acid (TXA) reduced the need for a blood transfusion in elderly patients treated with an intramedullary (IM) nail for an intertrochanteric fracture. DESIGN: Randomized prospective trial. SETTING: Academic level 1 trauma ce...
0
Incidence rates and life-time risk of hip fractures in Mexicans over 50 years of age: a population-based study
Management of Hip Fractures in the Elderly
The vast majority of hip fractures in the 21st century will occur in the developing countries. The rates and life-time hip fracture risk are not known for Mexico, and for this reason, we studied the incidence of hip fractures, and the remaining life-time probability of having a hip fracture at the age of 50 years in Me...
0
Screening for neurotoxic disease in humans
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Detection of neurotoxic disease is a formidable task requiring clinical, epidemiologic and detective skills. Rarely does neurotoxic insult occur in isolation, and rarely are precise details of the putative exposure known. False positive and false negative diagnoses of neurotoxicity are common because of the similarity ...
0
Expression and regulation of antimicrobial peptides in articular joints
SR for PM on OA of All Extremities
Articular joint infection is a surprisingly rare event considering the frequency of joint arthrocentesis and other invasive procedures applied to limb joints. This observation led us to the hypothesis that a local "chemical shield" in the form of antimicrobial proteins provides synovial membrane and articular cartilage...
1
Partial meniscectomy in the presence of severe osteoarthritis does not hasten the symptomatic progression of osteoarthritis
AMP (Acute Meniscal Pathology)
PURPOSE: This study had 2 aims: to determine whether arthroscopic partial meniscectomy improved symptoms in patients with a torn meniscus and severe degenerative change and to determine whether meniscectomy hastened the symptomatic progression of osteoarthritis in these patients. TYPE OF STUDY: An outcome study. METHOD...
1
Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
OAK 3 - Non-arthroplasty tx of OAK
Although glucosamine and chondroitin sulfate have showed beneficial effects on joint tissues in osteoarthritis (OA), their therapeutic use in the clinical setting is still debatable. Hence, a systematic review and meta-analysis of randomized placebo-controlled trials was conducted to investigate the efficacy of glucosa...
0
The bactericidal effects of an acidified sodium chlorite-containing oral moisturizing gel: a pilot study
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The aim of this study was to examine the bactericidal effects and bactericidal time of an acidified sodium chlorite compound gel (ASC-Gel) on bacteria isolated from the peri-implant sulci of 10 patients who received implants 3-27 years previously, and the depth of each peri-implant sulcus was 5 mm or less. Porphyromona...
0
Mid-term results for metaphyseal sleeves in revision knee surgery
PJI DX Updated Search
PURPOSE: Metaphyseal titanium sleeves have been used to provide cementless fixation in challenging bone defects in revision knee arthroplasty. The aim of this study was to evaluate the mid-term results of radiological and clinical outcomes, for metaphyseal sleeves in type 1B and 2 defects of tibia and femur under the h...
0
Influence of visual impairment level on the regulatory mechanism used during the approach phase of a long jump
Upper Eyelid and Brow Surgery
The purpose of the study was to investigate the occurrence of stride regulation at the approach phase of the long jump in athletes with normal vision and visually deprived Class F12 and F13 athletes. All the athletes exhibited the presence of a regulatory mechanism. In the normal vision group this occurred on the fifth...
1
Proximal deep vein thrombosis after hip replacement for oncologic indications
Management of Hip Fractures in the Elderly
BACKGROUND: Patients with cancer who undergo surgery about the hip are at increased risk for the development of deep vein thrombosis. We implemented a program of chemical and mechanical prophylaxis to prevent this problem. This study was performed to assess the effectiveness of that program. METHODS: Eighty-seven conse...
0
The brain tumor of George Gershwin and the legs of Cole Porter
DoD LSA (Limb Salvage vs Amputation)
George Gershwin died in 1937 of a glioblastoma of the right temporal lobe. He had been in psychoanalytical care for some time and was hospitalized a few weeks before his death, when he was thought to have a functional illness. The controversies about George Gershwin's death, duration of neurologic symptoms, and problem...
1
The efficacy of subcutaneous local analgesic infusion in the early postoperative period after bilateral total knee arthroplasty
AAHKS (8) Anesthetic Infiltration
OBJECTIVES: This study aims to evaluate the analgesic and functional efficacy of subcutaneous local analgesic infusion (ScLAI) in the early postoperative period (especially on the second postoperative day) in patients undergoing simultaneous bilateral total knee arthroplasty with an intraoperative periarticular injecti...
0
Bacteremia originating in the oral cavity. A review
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
In patients at risk because of heart disease, bacteremias induced by invasive dental treatments have been reported as a cause of bacterial endocarditis (BE) - a serious disorder that continues to involve a high mortality. As a result, different scientific societies have supported recommendations for the administration ...
0
Prevalence and characteristics of restless legs syndrome (RLS) in the elderly and the relation of serum ferritin levels with disease severity: Hospital-based study from Istanbul, Turkey
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The RLS is an underdiagnosed condition, characterized by unpleasant sensations in the legs. Pathophysiological mechanisms may include iron deficiency as reflected by low serum ferritin levels and dopaminergic system dysfunction. The purpose of our study was to investigate the prevalence and characteristics of RLS in th...
0
Positive Correlations Between Free Vitamin D and Bone Variables in a Group of Young Lebanese Women
Pediatric Diaphyseal Femur Fractures 2020 Review
Optimizing bone mass in adulthood is of great importance to prevent the occurrence of osteoporosis in later age. Vitamin D is an essential component of bone health. Low-serum vitamin D is associated with low bone mineral density (BMD), which is an important predictor of fracture risk. However, most cells, apart from re...
1
Early ultrasound diagnosis of developmental dysplasia of the hip
Developmental Dysplasia of the Hip CPG
The results of ultrasound diagnosis of developmental dysplasia of the hip (DDH) in several studies of 1,000 and 1,332 consecutive patients, performed according to Graf's method from 1984 to the present, are presented. Prior to 1984 the authors used radiography exclusively in suspected cases of DDH, however, the change ...
0
The outcome of partial arthroplasty for treatment of type 1 intertrochanteric fractures in Iraqi elderly patients
DoD SSI (Surgical Site Infections)
Background: When a fracture affects the proximal end of the femur at an extracapsular location and between the greater and the lesser trochanter, a dense trabecular type of bone, the fracture is known as intertrochanteric fracture. Indeed, there are two principal risk factors for fractures affecting the proximal end of...
0
Does obesity really make the femur stronger? BMD, geometry, and fracture incidence in the women's health initiative-observational study
Management of Hip Fractures in the Elderly
Heavier individuals have higher hip BMD and more robust femur geometry, but it is unclear whether values vary in proportion with body weight in obesity. We studied the variation of hip BMD and geometry across categories of body mass index (BMI) in a subset of postmenopausal non-Hispanic whites (NHWs) from the Women's H...
0
A multicentric, open-label, randomized, comparative clinical trial of two different doses of expanded hbm-mscs plus biomaterial versus iliac crest autograft, for bone healing in nonunions after long bone fractures: Study protocol
Hip Fx in the Elderly 2019
ORTHOUNION is a multicentre, open, comparative, three-arm, randomized clinical trial (EudraCT number 2015-000431-32) to compare the efficacy, at one and two years, of autologous human bone marrow-derived expanded mesenchymal stromal cell (hBM-MSC) treatments versus iliac crest autograft (ICA) to enhance bone healing in...
1
Tramadol as adjunct to psoas compartment block with levobupivacaine 0.5%: a randomized double-blinded study
AAHKS (9/10) Regional Nerve Blocks
BACKGROUND: Tramadol has been administered peripherally to prolong analgesia after brachial plexus and neuraxial blocks. Our aim was to evaluate the systemic and perineural effects of tramadol as an analgesic adjunct to psoas compartment block (PCB) with levobupivacaine. METHODS: In a randomized, prospective, double-bl...
0
The role of low intensity pulsed ultrasound therapy in the management of acute fractures: a systematic review
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: The aim of this study was to review the evidence regarding the use of low intensity pulsed ultrasound (LIPUS) in the management of acute long bone fractures. METHODS: Systematic review of Medline, Embase, and CINAHL databases. Further published studies were retrieved by hand searching bibliographies of rele...
0
Risk factors for hip fracture in Japanese elderly women with osteoporosis: applicability of biochemical markers in bone turnover
Management of Hip Fractures in the Elderly
AIM: The purpose of this study was to investigate risk factors for hip fracture in 169 Japanese elderly women. METHODS: Patients were divided into three groups: 53 patients had osteoporosis with hip fractures (FX-G), 59 patients had osteoporosis without hip fractures (NFX-G) and 57 patients had low back pain with neith...
1
Hemodynamic and metabolic effects of ketamine anesthesia in the geriatric patient
Management of Hip Fractures in the Elderly
The cardiovascular and metabolic effects of ketamine as the sole anesthetic agent for surgical correction of fractured neck of femur were studied in eight spontaneously breathing geriatric patients (mean age 83 years) before premedication, at the end of operation, and 15 min and 2 h after the end of anesthesia. Arteria...
0
Single-Staged Total Body Lift after Massive Weight Loss
Panniculectomy & Abdominoplasty CPG
This is a retrospective clinical report of a single-staged total body lift in 8 massive weight loss patients. While the combination of circumferential abdominoplasty, a modified lower body lift, and medial thighplasty adequately treats the lower torso and thighs, the residual skin laxity in the upper torso and breasts ...
0
Primary motor cortex involvement in initial learning during visuomotor adaptation
Pediatric Supracondylar Humerus Fracture 2020 Review
Human motor behaviour is continually modified on the basis of errors between desired and actual movement outcomes. It is emerging that the role played by the primary motor cortex (M1) in this process is contingent upon a variety of factors, including the nature of the task being performed, and the stage of learning. He...
1
Preemptive analgesia with bupivacaine in reduction mammaplasty: a prospective, randomized, double-blind, placebo-controlled trial
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: Preincisional analgesia is an antinociceptive treatment that prevents altered central excitability from high-intensity noxious stimuli. To determine the analgesic efficacy of preoperative infiltration with bupivacaine for reduction mammaplasty, a randomized, double-blind, placebo-controlled trial was design...
0
Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodelling of human skeletal muscle
Pediatric Supracondylar Humerus Fracture 2020 Review
AIMS: We assessed focal adhesion kinase (FAK) response to concentric (CON) vs eccentric (ECC) resistance training (RT) at two vastus lateralis (VL) sites, and the relationships between FAK, muscle protein synthesis (MPS) and morphological remodelling. METHODS: Six young males trained both legs unilaterally 3 times/wee...
0
Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty
PJI DX Updated Search
Background and purpose - Obesity increases the risk of deep infection after total joint arthroplasty (TJA). Our objective was to determine whether there may be body mass index (BMI) and weight thresholds indicating a higher prosthetic joint infection rate.Patients and methods - We included all 9,061 primary hip and kne...
0
Quality of life after dislocation of hip arthroplasty: a prospective cohort study on 319 patients with femoral neck fractures with a one-year follow-up
Management of Hip Fractures in the Elderly
PURPOSE: A primary arthroplasty constitutes a standard procedure in the treatment of patients with displaced fractures of the femoral neck. Although dislocation of the prosthesis remains a significant clinical problem, there are no previous reports on its influence on health-related quality of life (HRQoL). We analysed...
1
An outcomes analysis of 2142 breast reduction procedures
Reduction Mammoplasty for Female Breast Hypertrophy
BACKGROUND: Breast reduction alleviates macromastia symptoms and facilitates symmetrical breast reconstruction after cancer treatment. We investigated a large series of consecutive breast reductions to study important factors that impact outcomes. METHODS: An institutional review board-approved, retrospective review of...
1
Long-Term Adherence and Effectiveness of a Multicomponent Intervention for Community-Dwelling Overweight Thai Older Adults with Knee Osteoarthritis: 1-Year Follow Up
OAK 3 - Non-arthroplasty tx of OAK
Being overweight is a major risk factor for developing knee osteoarthritis (OA). The purpose of the current study was to: (a) determine participant adherence to a quadriceps exercise and weight management program after completion of the intervention; and (b) examine whether a quadriceps exercise and weight management p...
0
Pattern of rheumatic diseases in two outpatient clinics in Iran: Similarities with some different features
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Background: Rheumatic diseases are among the most prevalent diseases recognized in the world. Musculoskeletal disorders are one of the main causes of disability around the world and expend a large amount of health care and social resources and have a substantial impact on the quality of life of those affected. To ident...
1
Single Shot vs 24hr vs 48hr Continuous Adductor Canal Block After TKA
AAHKS (4) Acetaminophen
If the patient is willing to participate and signs the consent, he/she will be randomized to one of the three treatment groups: 1. Single shot block 2. 24 hour catheter 3. 48 hour catheter The choice of anesthetic technique will be at the discretion of the anesthesiologist. In our institution we usually advocate for sp...
0
Effects of photobiomodulation therapy, pharmacological therapy, and physical exercise as single and/or combined treatment on the inflammatory response induced by experimental osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Osteoarthritis (OA) triggers increased levels of inflammatory markers, including prostaglandin (PG) E<sub>2</sub> and proinflammatory cytokines. The elevation of cytokine levels is closely associated with increased articular tissue degeneration. Thus, the use of combination therapies may presumably be able to enhance t...
0
Predictors of short-term hip fracture rehabilitation outcomes in a tertiary hospital
Hip Fx in the Elderly 2019
Hip fracture patients often spend short periods of time in an acute hospital for rehabilitation. Tertiary hospitals have rehabilitation programs after hip surgery to re-integrate these patients back to community. We conducted a study to identify factors affecting short-term outcomes at the point of hospital discharge. ...
1
Treatment of reducible unstable fractures of the distal radius in adults: a randomised controlled trial of De Palma percutaneous pinning versus bridging external fixation
Distal Radius Fractures
BACKGROUND: At present, there is no conclusive evidence regarding the best treatment method for reducible unstable fractures of the distal radius. This study compared the effectiveness of two methods used in surgical treatment of such fractures: percutaneous pinning and external fixation. METHODS: We randomly allocated...
0
A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee
OAK 3 - Non-arthroplasty tx of OAK
OBJECTIVE: To compare the safety and effectiveness of a high molecular weight hyaluronan produced by biological fermentation (Bio�HA) with those of avian�derived hyaluronan that uses cross�linking to achieve high molecular weight (CL�HA). DESIGN: This was a prospective, multicenter, randomized, double�blind t...
0
Updates in biological therapies for knee injuries: menisci
AMP (Acute Meniscal Pathology)
The preservation of meniscal tissue is paramount for long-term joint function, especially in younger patients who are athletically active. Many studies have reported encouraging results following the repair of meniscus tears, including both simple longitudinal tears located in the periphery and complex multiplanar tear...
1
Negative pressure wound therapy for surgical wounds healing by primary closure
DoD SSI (Surgical Site Infections)
BACKGROUND: Indications for the use of negative pressure wound therapy (NPWT) are broad and include prophylaxis for surgical site infections (SSIs). Existing evidence for the effectiveness of NPWT on postoperative wounds healing by primary closure remains uncertain. OBJECTIVES: To assess the effects of NPWT for prevent...
0
Elbow hemiarthroplasty using a "triceps-on" approach for the management of acute distal humeral fractures
Pediatric Supracondylar Humerus Fracture 2020 Review
Background: Total elbow arthroplasty is an established option for the primary treatment of acute distal humeral fractures, but there are sparse data regarding elbow hemiarthroplasty (EHA) as an alternative. We present the outcome of EHA performed with a modular anatomic prosthesis and a "triceps-on" surgical technique....
0
Risk factors for foot and ankle disorders among assembly plant workers
DoD PRF (Psychosocial RF)
BACKGROUND: Jobs that necessitate prolonged standing and walking activities are commonly associated with worker's complaints of foot and ankle pain. The objective of this study was to determine the relative contributions of work activity (time spent standing, walking, or sitting), floor surface characteristics, weight,...
0
Development and Validation of a Clinical Risk Score for Intensive Care Resource Utilization After Colon Cancer Surgery: a Practical Guide to the Selection of Patients During COVID-19
Coronavirus Disease 2019 (COVID-19)
BACKGROUND: The purpose of this study was to develop and validate a prediction model and clinical risk score for Intensive Care Resource Utilization after colon cancer surgery. METHODS: Adult (â?¥ 18 years old) patients from the 2012 to 2018 ACS-NSQIP colectomy-targeted database who underwent elective colon cancer surg...
1
Bridging anticoagulation in patients treated with vitamin K antagonists prior to trochanteric and hip fracture surgeries: The current practice
Hip Fx in the Elderly 2019
BACKGROUND: The strategies of perioperative bridging anticoagulation in orthopedic surgical patients during oral anticoagulation (OAC) therapy with vitamin K antagonists (VKA) vary from center to center. OBJECTIVES: The aim of this single-center study was to assess the risk of bleeding and thromboembolic events (TEs) i...
0
Prediction of radionuclide bone imaging findings by Gleason histologic grading of prostate carcinoma
MSTS 2018 - Femur Mets and MM
To evaluate a relationship between Gleason scores and Tc-99m HMDP bone imaging findings, data from 48 men (aged 45 to 77; mean, 67) with prostate carcinoma who had a bone imaging study at the time of presentation were reviewed. Cumulative Gleason scores were divided into two groups: high scores (6-10), 32 men; low scor...
1
Comparing the efficacy of pain managements after total hip arthroplasty: A network meta-analysis
AAHKS (9/10) Regional Nerve Blocks
The aim of our current study is to compare efficiency of various interventions implemented for pain management after total hip arthroplasty (THA). PubMed and EMBASE were searched for randomized clinical trials (RCTs) reporting the pain scales for evaluate the efficacy of pain control after THA including at least one pa...
0
Role of metaphyseal cancellous bone defect size in secondary displacement in Colles' fracture
Distal Radius Fractures
The purpose of this study was to evaluate the role of the metaphyseal cancellous bone defect size in secondary dislocation of Colles' fracture. Thirty-five patients with a dislocated Colles' fracture were examined by computed tomography (CT) for metaphyseal bone defects. The size of the defect was assessed and related ...
0
Cost-Effectiveness of five commonly used prosthesis brands for total knee replacement in the UK: A study using the NJR Dataset
OAK 3 - Non-arthroplasty tx of OAK
Background There is a lack of evidence on the effectiveness or cost-effectiveness of alternative brands of prosthesis for total knee replacement (TKR).We compared patient-reported outcomes, revision rates, and costs, and estimated the relative cost-effectiveness of five frequently used cemented brands of unconstrained ...
1
The effect of bone morphogenetic protein 2 composite materials combined with cannulated screws in treatment of acute displaced femoral neck fractures
Hip Fx in the Elderly 2019
The risk of avascular necrosis (AVN) and nonunion after treatment of displaced femoral neck fractures is increased in patients aged <60 years. Therefore we established a new protocol for closed reduction and internal fixation (CRIF) using cannulated screws combined with bone morphogenetic protein 2 (BMP-2) composite ma...
0
Avascular necrosis of femoral and/or humeral heads in multiple myeloma: results of a prospective study of patients treated with dexamethasone-based regimens and high-dose chemotherapy
AAHKS (8) Anesthetic Infiltration
PURPOSE: To assess the prevalence, time of onset, risk factors, and outcome of avascular necrosis (AVN) of bone in patients with multiple myeloma undergoing antineoplastic therapy. PATIENTS AND METHODS: A total of 553 consecutive assessable patients were enrolled onto a treatment protocol consisting of dexamethasone-co...
1
Incident opioid use and risk of hip fracture among persons with Alzheimer disease: a nationwide matched cohort study
Hip Fx in the Elderly 2019
The objective of this study was to investigate whether incident opioid use is associated with an increased risk of hip fractures among community-dwelling persons with Alzheimer disease (AD) and to assess the association in terms of duration of use and opioid strength. Among community-dwelling persons with AD diagnosed ...
0
Analgesic effect of raloxifene on back and knee pain in postmenopausal women with osteoporosis and/or osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
To assess the effect of raloxifene on bone and joint pain, 24 postmenopausal women with back or knee pain or both were randomly divided into two groups, based on the chronological sequence of consultation, to be treated with 60 mg raloxifene and 1 microg alfacalcidol (RA)/day (group RA) or 1 microg alfacalcidol alone (...
0
Abnormalities of parietal and prerolandic somatosensory evoked potentials in Hungtington's disease
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Cervical, parietal and prerolandic somatosensory evoked potentials (SEPs) to median nerve stimulation at the wrist were recorded with an earlobe reference in 24 patients with Hungtington's disease (HD) and in 24 age-matched normal controls. Cortical responses of abnormal wave form and reduced amplitude were constantly ...
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Awareness of putative risk factors for Alzheimer's disease among elderly Koreans
DoD PRF (Psychosocial RF)
Objective: Although there are rapidly growing concerns about the high rates of cognitive dysfunction in Korea, the knowledge of risk factors for Alzheimer's disease (AD) among the general public in Korea remains to be elucidated. Methods: A total of 2767 randomly selected subjects from the Ansan Geriatric Study were qu...
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Development of a Comprehensive, Nonsurgical Joint Health Program for People With Osteoarthritis: A Case Report
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND AND PURPOSE: Existing osteoarthritis (OA) care models often fall short in addressing the many biological, psychological, social, and behavioral characteristics that contribute to disability. As US health care shifts towards value-based payment, there is an increasing need to develop and test scalable, cost-e...
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ASCOT: Autologous Bone Marrow Stem Cell Use for Osteoarthritis of the Thumb-First Carpometacarpal Joint
Glenohumeral Joint OA
BACKGROUND: The first carpometacarpal joint (CMCJ) in the hand is a commonly affected joint by osteoarthritis. It causes significant thumb base pain, limiting functional capacity. Microfracturing and application of autologous stem cells has been performed on large joints such as the knee but has never been evaluated fo...
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Inter-rater agreement and accuracy of clinical tests used in diagnosis of Carpal Tunnel Syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
A sample of 42 subjects (84 hands) with complaints of pain, numbness and/or tingling were used to study the inter-rater agreement and accuracy of seven clinical tests which can be used to assist in the diagnosis of carpal tunnel syndrome (CTS). A 'gold standard diagnosis', defined as a clinical diagnosis of CTS rendere...
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Ultrasound-Guided Arterial Access: Outcomes among Patients with Peripheral Artery Disease and Critical Limb Ischemia Undergoing Peripheral Interventions
DOD - Acute Comp Syndrome CPG
OBJECTIVE: Arterial cannulation is a vital component of endovascular interventions and often unconventional access approaches are required due to disease complexity. Historically, varying maneuvers have been utilized to obtain arterial access. Lack of consensus exists regarding the safest and most effective method. Thi...
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Mycobacterium tuberculosis infection within Warthin's tumor: Report of two cases
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We report two patients with Warthin's tumor who were also infected with Mycobacterium tuberculosis. Case 1 was a 75-year-old woman with Warthin's tumor and multiple small epithelioid granulomas with caseous necrosis involving the submandibular gland. This patient died of tuberculous meningitis 4 months after biopsy. Ca...
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The painful primary hip replacement - review of the literature
PJI DX Updated Search
Total hip replacement is one of the most successful surgical procedures of the 20th century (World Health Organisation). The success rate is dependent on the chosen endpoint. Evaluation of the outcome in joint replacement surgery has shifted from the revision rate toward patient satisfaction and quality of life. Patien...
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Efficacy of a Procedure-Specific Education Module on Informed Consent in Plastic Surgery
Panniculectomy & Abdominoplasty CPG
INTRODUCTION: Truly informed consent is an elusive goal, seldom attained in medical or surgical practice. Patients often do not fully understand procedures and therapies they undergo or the associated sequelae. Historically, informed consent and patient education have been limited to physician discussions, sometimes wi...
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Articular fractures of the distal radius
Distal Radius Fractures
Fractures of the distal radius are frequently biarticular injuries and comprise four basic components. Displacement of the key medial fragments and their strong ligamentous attachments (termed the medial complex) is the basis for a useful classification into four fracture types. Optimal management requires precise corr...
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Subchondral insufficiency fracture of the femoral head in elderly people
Hip Fx in the Elderly 2019
We evaluated the clinical course of subchondral insufficiency fracture of the femoral head (SIFFH) and its characteristic findings with special regard to joint space narrowing (JSN). Thirty-one cases of SIFFH of mean age 68.9 yr initially underwent limited weight-bearing conservative treatment. During the follow-up per...
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Prevalence and distribution of air in the leg on preoperative multidetector high-resolution computed tomography in closed and low-grade open tibial shaft fractures
DoD SSI (Surgical Site Infections)
PURPOSE: The prevalence and distribution of air present in the leg in closed and low-grade open tibial shaft fractures are unknown on multidetector high-resolution computed tomography (CT). The purpose of this study was to determine the rate of surgical site infection (SSI) in cases where debridement was not performed ...
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Technique for Intramedullary Stabilization of Ulnar Neck Fractures
Distal Radius Fractures
BACKGROUND: Distal ulna fractures at the ulnar neck can be seen in association with distal radius fractures, and multiple techniques have been described to address the ulnar neck component of these injuries. We have found that treatment of ulnar neck fractures can be challenging in terms of anatomy and fracture fixatio...
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Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
Estrogen-dependent osteoarthritis (EDPOA) is a disease of perimenopausal-age women. Their manifestations are polyarticular pain with common co-morbidities (carpal tunnel syndrome, insomnia, fatigue, depression, and fibromyalgia). Based on dual role of glucocorticoids, its trophic action on the chondrocyte and its anti-...
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Clinical usefulness of blood metal measurements to assess the failure of metal-on-metal hip implants
PJI DX Updated Search
In April 2010, a Medicines and Healthcare Products Regulatory Agency safety alert concerning all metal-on-metal (MOM) hip replacements recommended measuring chromium and cobalt concentrations when managing patients with painful prostheses. The need for this review is illustrated by the recent surge in requests for thes...
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Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
OBJECTIVE: C-reactive protein (CRP) has been associated with disease progression in patients with osteoarthritis (OA), but the reasons for this remain unclear. We hypothesized that higher CRP would be related to local inflammatory findings in the joints of patients with OA. METHODS: Plasma and synovial membrane specime...
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Local effects of malignancy on bone
MSTS 2018 - Femur Mets and MM
PURPOSE OF REVIEW: Skeletal-related complications occur commonly in many solid tumors including breast, prostate and lung cancer as well as multiple myeloma. In addition, malignancies and their associated treatment may result in bone loss or osteoporosis. This review will focus solely on recent data associated with met...
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Selection of operative procedures for cubital tunnel syndrome
Diagnosis and Treatment of Carpal Tunnel Syndrome CPG
The purpose of this study was to investigate the primary operative procedures that are performed by hand surgeons for cubital tunnel syndrome and their reported satisfaction with these procedures. The survey consisted of 22 questions regarding primary operative treatment of cubital tunnel syndrome and demographics and ...
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Progression of acromegalic arthropathy despite long-term biochemical control: A prospective, radiological study
OAK 3 - Non-arthroplasty tx of OAK
Objective: Arthropathy is an invalidating complication of acromegaly, of which the prognosis and determinants are currently unknown in treated acromegaly. Therefore, the objective of the present study was to investigate the radiographic progression of arthropathy over a mean follow-up period of 2.6 years and determinan...
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Hispanic Established Populations for the Epidemiologic Studies of the Elderly: Selected longitudinal findings
HipFx Supplemental Cost Analysis
The aim of this report is to present key findings from the Hispanic Established Populations for the Epidemiological Studies of the Elderly. This unique study began in 1993-1994 with 3050 Mexican-Americans aged 65 years or older who lived in California, Arizona, New Mexico, Colorado and Texas (USA). The subsequent four ...
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Dental health knowledge, attitude and practice on the occurrence of dental caries among adolescents in a local government area (LGA) of Oyo state, Nigeria
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
This study was carried out in order to identify the extent of dental caries occurrence and to relate it with the dental health knowledge, attitude and practice among adolescents in Ibadan North (LGA) of Oyo State Nigeria. Descriptive survey research design was adopted for the study. Self structured questionnaire and de...
1
A systematic review of the role bisphosphonates in metastatic disease
MSTS 2018 - Femur Mets and MM
Objectives: To identify evidence for the role of bisphosphonates in malignancy for the treatment of hypercalcaemia, prevention of skeletal morbidity and use in the adjuvant setting. To perform an economic review of current literature and model the cost effectiveness of bisphosphonates in the treatment of hypercalcaemia...