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1 | Patient-specific versus conventional instrumentation for total knee arthroplasty: Peri-operative and cost differences | Surgical Management of Osteoarthritis of the Knee CPG | The role of patient-specific instrumentation in total knee arthroplasty (TKA) is yet to be clearly defined. Current evidence evaluating peri-operative and cost differences against conventional TKA is unclear. We reviewed 356 TKAs between July 2008 and April 2013; 306 TKAs used patient-specific instrumentation while 50 ... |
0 | Pseudoachondroplastic spondyloepiphyseal dysplasia | Surgical Management of Osteoarthritis of the Knee CPG | At least four distinct forms of PsA-SED can be recognized. Inheritance is autosomal dominant in two and autosomal recessive in the other two varieties. Based on two facts, i.e. severity of the disease and the other family members being normal, our patient may fall into the fourth group of PsA-SED classification. These ... |
1 | Models for Predicting Early Death in Patients With Stage IV Esophageal Cancer: A Surveillance, Epidemiology, and End Results-Based Cohort Study | MSTS 2022 - Metastatic Disease of the Humerus | BACKGROUND: Despite enormous progress in the stage IV esophageal cancer (EC) treatment, some patients experience early death after diagnosis. This study aimed to identify the early death risk factors and construct models for predicting early death in stage IV EC patients.
METHODS: Stage IV EC patients diagnosed between... |
0 | Minimally invasive procedures for urethral incontinence: Is there a role for laparoscopy? | Panniculectomy & Abdominoplasty CPG | This article focuses on the minimally invasive surgical approaches for the treatment of stress urinary incontinence (SUI). The role of laparoscopic suspension is reviewed and compared with other minimally invasive techniques, such as the pubovaginal sling procedure and injection of the urethral bulking agents. The role... |
0 | Association of Common Variants in TGFA with Increased Risk of Knee Osteoarthritis Susceptibility | OAK 3 - Non-arthroplasty tx of OAK | OBJECTIVE: Osteoarthritis (OA) is a complex degenerative joint disorder, which has contributions from both environmental and genetic factors. Several recent publications have established the connection between hip OA susceptibility and genetic markers within the TGFA gene, however, the relationship of these markers wit... |
0 | Do for-profit health plans restrict access to high-cost procedures? | DoD PRF (Psychosocial RF) | Question. Do for-profit health plans restrict access to high-cost procedures compared with not-for-profit health plans? Study design. Cohort study. Main results. In unadjusted analyses, for-profit health plan beneficiaries had higher rates of all high-cost procedures than not-for-profit health plan beneficiaries; the d... |
0 | A Bayesian Approach to Age-at-Death Estimation from Osteoarthritis of the Shoulder in Modern North Americans | Glenohumeral Joint OA | Osteoarthritis (OA) is a marker of degeneration within the skeleton, frequently associated with age. This study quantifies the correlation between OA and age-at-death and investigates the utility of shoulder OA as a forensic age indicator using a modern North American sample of 206 individuals. Lipping, surface porosit... |
1 | Systematic Review of Orthopaedic and Sports Medicine Injuries and Treatment Outcomes in Women's National Basketball Association and National Basketball Association Players | AMP (Acute Meniscal Pathology) | Background: Athletes in the Women’s National Basketball Association (WNBA) and National Basketball Association (NBA) are subject to high injury rates given the physical demands of the sport. Comprehensive data regarding injury patterns and rates in these athletes are limited. Purpose: To summarize available data on ort... |
0 | Pioneering technique using Acellular Dermal Matrix in the rescue of a radiation ulcer | Acellular Dermal Matrix | BACKGROUND: Radiotherapy as an adjuvant to mastectomy is integral to the treatment of breast cancer, but can result in skin ulceration. Skin ulceration following radiotherapy is traditionally managed by removing the implant and allowing the skin to heal by secondary intention. CASE REPORT: A 42-year-old woman underwent... |
0 | Morphine consumption post-arthroplasty in patients with severe haemophilia: Is the peripheral nerve block still contraindicated? | Surgical Management of Osteoarthritis of the Knee CPG | Introduction: Peripheral nerve blocks (PNBs) have dramatically improved patients' postoperative rehabilitation in orthopedic surgery (OS), particularly through a decrease in the need for morphine. PNBs are usually considered as a contraindication in patients with hemophilia, who are only treated with opioids. Aim: To e... |
0 | Collaborative Model of Care Between Orthopaedics and Allied Healthcare Professionals Trial (CONnACT) | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND With a rapidly aging population, osteoarthritis is expected to become the 4th leading cause of global disability by 2020. Established guidelines for knee osteoarthritis strongly advocate lifestyle changes, such with exercises and weight loss as first line of treatment, whilst reserving surgery as the last re... |
0 | Arthroscopic Meniscal Root Repair Using a Ceterix NovoStitch Suture Passer | AMP (Acute Meniscal Pathology) | Meniscal root injuries can compromise knee function and lead to early degenerative changes if not appropriately treated. Numerous techniques have been described; however, the technical difficulties in performing these repairs are well known. Furthermore, the relative strengths of various repair techniques have been exa... |
1 | Risk factors and diagnosis of developmental dysplasia of hip in children | Developmental Dysplasia of the Hip CPG | Developmental dysplasia of hip (DDH) is one entity one occasionally comes across while in a busy orthopaedic or paediatric outpatient department. The knowledge of risk factors and awareness of the condition is must for every orthopaedic surgeon and paediatrician as well lest the diagnosis will be missed. An early diagn... |
0 | Collagene order of articular cartilage by clinical magnetic resonance images and its age dependency | AMP (Acute Meniscal Pathology) | The present paper describes a novel method to obtain information on the degree of order of the collagen network of the knee meniscal cartilage by means of a single clinical MRI. Images were obtained from 34 healthy volunteers aged between 6 and 76 years as well as from one patient with clinically-diagnosed arthrosis at... |
1 | Platelet count, antiplatelet therapy and pulmonary embolism--a prospective study in patients with hip surgery | Management of Hip Fractures in the Elderly | Pulmonary embolism (PE) is a serious complication following hip surgery. Trials of antiplatelet thromboprophylaxis indicated a substantial reduction in PE rate, and we prospectively studied the effect of a combination of low-dose heparin and two different antiplatelets. Furthermore, our experience in previous studies s... |
0 | The trauma of suction-assisted lipectomy cannula on flap circulation in rats | Panniculectomy & Abdominoplasty CPG | The effect of suction-assisted lipectomy on cutaneous blood vessels of inguinal skin flaps was studied and compared in 191 rats. Different types of cannula tips were used; the number of passes was standardized. In one experiment, following suctioning, 3 X 2 cm groin island flaps based on inferior epigastric pedicles we... |
0 | A New Procedure for Wrapped-Negative Pressure Wound Therapy for Congestion After Arterialized Venous Flap Surgery | DoD SSI (Surgical Site Infections) | Negative pressure wound therapy (NPWT) is a method for treating wound. However, there are no case reports using NPWT for treating congestion after arterialized venous flap. Therefore, this study reported favorable outcomes after using a single-use NPWT system for managing congestion. A 39-year-old man had his index fin... |
0 | Biomaterials in search of a meniscus substitute | AMP (Acute Meniscal Pathology) | The menisci fulfill key biomechanical functions in the tibiofemoral (knee) joint. Unfortunately meniscal injuries are quite common and most often treated by (partial) meniscectomy. However, some patients experience enduring symptoms, and, more importantly, it leads to an increased risk for symptomatic osteoarthritis. O... |
1 | The thromboprophylactic effect of a low-molecular-weight heparin (Fragmin) in hip fracture surgery. A placebo-controlled study | Hip Fx in the Elderly 2019 | A prospective, randomized, double-blind trial concerning thromboprophylaxis in 82 patients in whom hip fracture surgery was performed was conducted to compare a new low-molecular-weight heparin (Fragmin) with placebo. Deep venous thrombosis (DVT) was detected by 125-I-fibrinogen uptake test followed by ascending phlebo... |
0 | Comparison of bony increased offset-reverse shoulder arthroplasty and standard reverse shoulder arthroplasty outcomes | DoD SSI (Surgical Site Infections) | The purpose of this study is to evaluate functional outcomes and complications between the standard RSA and BIO-RSA. 65 consecutive procedures were performed in 60 patients (40 BIO-RSA and 25 RSA). There was no statistically significant difference in functional outcome, pain and complications. The BIO-RSA can produce c... |
0 | Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation | MSTS 2018 - Femur Mets and MM | Patients who underwent autologous stem cell transplantation (ASCT) are prone to decreased bone mineral density (BMD). We measured BMD in 180 patients who underwent ASCT for hematologic malignancies. Patients were evaluated with a median of 6.2 years after ASCT. Twenty patients who received only chemotherapy were evalua... |
0 | All-Inside Arthroscopic Meniscal Stacked Suture Repair for Hypermobile Lateral Meniscus With FASTFIX 360 | AMP (Acute Meniscal Pathology) | Even though inside-out repair of meniscal tears is still the gold standard, the need for a posterior incision is a certain disadvantage of this approach. However, all-inside arthroscopic meniscal stacked suture repair can be performed for hypermobile lateral meniscus using all-inside devices and slotted canula. This te... |
0 | Exeter total hip arthroplasty with matte or polished stems | Management of Hip Fractures in the Elderly | OBJECTIVE: To compare implant survival rates after total hip arthroplasty with Exeter matte or polished stems and to determine the relationship of synovitis/joint effusion to signs of implant loosening and stem type |
1 | Heparin prophylaxis of deep vein thrombosis in patients with a fractured neck of the femur | Management of Hip Fractures in the Elderly | A double-blind controlled clinical trial of the efficacy of the prophylactic subcutaneous administration of calcium heparin in preventing deep vein thrombosis has been conducted in 50 patients with a fractured neck of the femur. Heparin was given every eight hours in a dose of 100 international units per kilogram of bo... |
0 | Physiological risk factors for falls in people with knee osteoarthritis before and early after knee replacement surgery | Surgical Management of Osteoarthritis of the Knee CPG | PURPOSE: Knee osteoarthritis (OA) is a major cause of disability and a risk factor for falls in older people. The purpose of this study was to assess the falls risk of people with knee OA before surgery and at 4 months following surgery and to compare this to a control group. METHODS: Thirty-five patients with knee OA ... |
0 | Association Between Meniscal and Chondral Lesions and Timing of Anterior Cruciate Ligament Reconstruction | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Rupture of the anterior cruciate ligament (ACL) is a common sports injury and is known to be associated with an increased risk of knee osteoarthritis. Several studies have indicated that the risk of additional injuries to the menisci and articular cartilage increases with delays in the treatment of ACL tear... |
1 | Analysis of initial injury radiographs of occult femoral neck fractures in elderly patients: a pilot study | Management of Hip Fractures in the Elderly | Diagnosis of occult hip fractures by initial radiographs remains challenging in the emergency department. Previously, the gold standard for accurate diagnosis of occult hip fractures was magnetic resonance imaging. This study used initial radiographs obtained in the emergency department to evaluate specific signs and m... |
0 | For Whom Does Time Heal Wounds? Individual Differences in Stability and Change in Posttraumatic Stress After the 2011 Oslo Bombing | DoD PRF (Psychosocial RF) | Prospective studies describing and predicting individual differences in the course of posttraumatic stress symptoms (PTSS) after disasters are scarce. The present study aimed to describe and predict individual differences in both the level and the rate of change in PTSS after the 2011 Oslo bombing, a terrorist attack d... |
1 | Subscapularis tenotomy vs. lesser tuberosity osteotomy during total shoulder arthroplasty: When less is more | Trial Systematic Review Project | Mobilization of the subscapularis is necessary during total shoulder arthroplasty, but high rates of subscapularis dysfunction have been reported postoperatively. Two methods are commonly used: subscapularis tenotomy with tendon-to-tendon repair and lesser tuberosity osteotomy with bone-to-bone repair. There is conflic... |
0 | Effect of carbamazepine and valproate on bone mineral density | Distal Radius Fractures | Objective: To examine the effect of carbamazepine and valproate monotherapy on bane mineral density in children. Methods: Axial (second, third, and fourth lumbar vertebrae) and appendicular (distal third of radius) bane mineral density was measured by dual-energy x-ray absorptiometry in 27 healthy children and 26 child... |
0 | Effect of chlorhexidine varnish application on streptoococcus mutans colonisation in adolescents with fixed orthodontic appliances | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | OBJECTIVE: The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in highlevel MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement. MATERIALS AND METHODS: The subjects of this single-blinde... |
0 | Does Patient Perception Differ Following Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty? A Simultaneous Bilateral Randomized Study | AAHKS (5) Gabapentinoids | Background Femoral nerve block (FNB) has been used as part of the multimodal analgesia after total knee arthroplasty (TKA), but leads to weakness in the quadriceps muscles. Recently, adductor canal block (ACB) was reported to provide effective pain relief while sparing the strength of the quadriceps. This simultaneous ... |
0 | Frequency distribution of F-latencies (DFL) has physiological significance and gives distribution of conduction velocity (DCV) of motor nerve fibres with implications for diagnosis | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | On electrical stimulation of a peripheral motor nerve, a delayed and reduced F-response is obtained, which is known to occur due to random backfiring of a few percent of the motor nerve fibres at the spinal end after antidromic conduction. F-latencies obtained from multiple stimulations vary in latency, size and shape ... |
0 | Single dose oral etoricoxib for acute postoperative pain in adults | SR for PM on OA of All Extremities | BACKGROUND: Etoricoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor prescribed for the relief of chronic pain in osteoarthritis and rheumatoid arthritis, and acute pain. The drug is believed to be associated with fewer upper gastrointestinal adverse effects than conventional non-steroidal anti-inflammatory drugs ... |
0 | The effect of 1-year transdermal estrogen replacement therapy on bone mineral density and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial | AAHKS (2) Corticosteroids | We studied the effect of 1-year transdermal estrogen replacement therapy (ERT) on bone mineral density (BMD) and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus (SLE) patients in a randomized, double-blind, placebo-controlled trial. SLE patients were randomly allocated to ... |
1 | Return to activities after breast reduction | Reduction Mammoplasty for Female Breast Hypertrophy | BACKGROUND: Uncertainty exists in the medical literature about recommendations for return to work or driving after breast reduction surgery.
METHODS: A survey was sent to 138 plastic surgeons in the United Kingdom enquiring about their recommended timing of return to work or driving a car depending of level of activity... |
0 | Practical approach to subject-specific estimation of knee joint contact force | OAK 3 - Non-arthroplasty tx of OAK | Compressive forces experienced at the knee can significantly contribute to cartilage degeneration. Musculoskeletal models enable predictions of the internal forces experienced at the knee, but validation is often not possible, as experimental data detailing loading at the knee joint is limited. Recently available data ... |
0 | Reimbursement for regional anesthesia in a bundled payment environment: A value proposition | Surgical Management of Osteoarthritis of the Knee CPG | Introduction: The bundled payment model, which coalesces reimbursement to multiple providers into a single payment, is a strategy that is being advocated to align incentives and control the rising costs of health care. This approach encourages hospitals and physicians to create a more efficient patient care model desig... |
0 | Regional bone density variations in osteoarthritic glenoids: a comparison of symmetric to asymmetric (type B2) erosion patterns | Glenohumeral Joint OA | BACKGROUND: Accurate characterization of regional variations in bone density in symmetric and asymmetric (B2) glenoid erosion patterns can assist with surgical planning, reaming, and component implantation. The purpose of this study was to characterize regional bone density and porosity in symmetric and asymmetric (B2)... |
0 | Knee arthroscopy under local anesthesia: The crete experience | Surgical Management of Osteoarthritis of the Knee CPG | Aim: The review and presentation of our clinical experience with knee arthroscopy under local anaesthesia and the evaluation of patient satisfaction Materials and Methods: Between February 2006 and March 2010, 242 patients (169 men and 73 women with an average age of 46 years) underwent unilateral primary knee arthrosc... |
0 | The effect of calcitriol on endoplasmic reticulum stress response | MSTS 2018 - Femur Mets and MM | Calcitriol, the active form of vitamin D, is known for its anticancer properties including induction of apoptosis, inhibition of angiogenesis, and metastasis. Calcitriol also increases intracellular calcium triggering apoptosis in a calpain-dependent manner. Since the main storage unit for cellular calcium is endoplasm... |
0 | The rheumatoid wrist | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | Wrist involvement is common in patients with rheumatoid arthritis. Individual patient assessment is important in determining functional deficits and treatment goals. Patients with persistent disease despite aggressive medical management are candidates for surgery. Soft-tissue procedures offer good symptomatic relief an... |
0 | Vascularized proximal fibular epiphyseal transfer for Bayne and Klug type III radial longitudinal deficiency in children | Distal Radius Fractures | BACKGROUND: Treatment of Bayne and Klug type III radial longitudinal deficiency with fibular epiphyseal transplantation in children has had limited success to date. The purpose of this investigation was to review the authors' results of microvascular epiphyseal transplantation for radial longitudinal deficiency.
METHOD... |
0 | Minimally invasive plate osteosynthesis for short oblique diaphyseal tibia fractures: does fracture site affect the outcomes? | DoD SSI (Surgical Site Infections) | OBJECTIVE: To report the results of patients with short oblique diaphyseal tibia fractures treated with minimally invasive plate osteosynthesis (MIPO). The secondary aim was to understand the effect of fracture location (midshaft or distal 1/3) on outcomes.
METHODS: Twenty-eight patients with short oblique (>30degree) ... |
0 | Fracture and bone mineral density in hemodialysis patients | Distal Radius Fractures | AIM: The aim of this cross-sectional study was to determine in hemodialysis patients the pattern of low trauma fracture, the ability of dual X-ray absorptiometry (DXA) to discriminate between patients with and without fracture, and the magnitude, distribution and mechanism of bone loss.
PATIENTS AND METHODS: Eighty-eig... |
0 | Calcium supplementation increases stature and bone mineral mass of 16- to 18-year-old boys | Management of Hip Fractures in the Elderly | The effect of calcium carbonate supplementation on bone growth and mineral accretion was studied in 143 boys aged 16-18 yr, randomized to 1000 mg Ca/d or a matching placebo for 13 months. Anthropometry and dual-energy x-ray absorptiometry of the whole body, lumbar spine, hip, and forearm were performed before, during, ... |
0 | Spinal anesthesia versus general anesthesia for hip fracture repair: a longitudinal observation of 741 elderly patients during 2-year follow-up | Management of Hip Fractures in the Elderly | The Baltimore Hip Studies, a multicenter, noninterventional, observational trial, provided an opportunity to investigate the effects of anesthetic technique on the long-term outcome of elderly patients after hip fracture repair. Detailed interviews assessing functional status and pain were conducted during the hospital... |
0 | Effect of general anesthesia on the abnormal immune response in patients with rheumatoid arthritis | AAHKS (2) Corticosteroids | Objective. To evaluate the influence of mental stress on the neuroendocrine-immune system in patients with rheumatoid arthritis (RA). Methods. Twenty-four patients with RA and 10 patients with osteoarthritis (OA) who underwent total knee or hip arthroplasty under general anesthesia were enrolled in this study. The bloo... |
0 | Running injuries - changing trends and demographics | DoD - ACS - Interrater Reliability | Running injuries are common. Recently the demographic has changed, in that most runners in road races are older and injuries now include those more common in master runners. In particular, Achilles/calf injuries, iliotibial band injury, meniscus injury, and muscle injuries to the hamstrings and quadriceps represent hig... |
0 | Impact of the fibula fractures and syndesmotic injuries on the prognosis of the tibial pilon fractures | OAK 3 - Non-arthroplasty tx of OAK | Aim: To evaluate tibial pilon fractures, as well as the type of fibula fracture, and the presence of injury to the inferior tibiofibular joint. Materials and methods: The study included 42 patients (34 male, 8 female) who underwent surgery for pilon fractures and were followed up. The mean follow-up period of the patie... |
0 | A review of therapeutic ultrasound: effectiveness studies | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | BACKGROUND AND PURPOSE: Therapeutic ultrasound is one of the most widely and frequently used electrophysical agents. Despite over 60 years of clinical use, the effectiveness of ultrasound for treating people with pain, musculoskeletal injuries, and soft tissue lesions remains questionable. This article presents a syste... |
0 | Plate and screw fixation of bicolumnar distal humerus fractures: Factors associated with loosening or breakage of implants or nonunion | Pediatric Supracondylar Humerus Fracture 2020 Review | Purpose To identify factors associated with reoperation for early loosening or breakage of implants or nonunion after operative treatment of AO type C distal humerus fractures. Methods We retrospectively analyzed 129 adult patients who had operative treatment of an isolated AO type C distal humerus fracture at 1 of 5 h... |
0 | Prognostic value of CC-chemokine receptor seven expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor | MSTS 2018 - Femur Mets and MM | BACKGROUND: CC-chemokine receptor seven (CCR7), a G-protein coupled receptor normally facilitating immune cells lymphatic homing, has recently been identified on several cancer cells in promoting invasion and lymphatic specific metastasis by mimicking normal leukocytes. As tyrosine kinase inhibitors for metastatic rena... |
1 | A randomized controlled trial to evaluate intensity of community-based rehabilitation provision following stroke or hip fracture in old age | Management of Hip Fractures in the Elderly | OBJECTIVE: To compare intensive with non-intensive home-based rehabilitation provision following stroke or hip fracture in old age (65 years+). DESIGN: Parallel single-blind randomized control trial. SETTING: Domiciliary provided multidisciplinary rehabilitation. SUBJECTS: One hundred and sixty patients aged 65 or over... |
0 | Risk for osteopenia and osteoporosis in institution-dwelling individuals with intellectual and/or developmental disabilities | DoD PRF (Psychosocial RF) | The purpose of this study was to investigate the prevalence of and contributing factors to osteopenia and osteoporosis among people with intellectual disabilities (ID) or/and developmental disabilities (DD) residing in a disability institution in Taiwan. The present study was conducted at one disability institution in ... |
0 | Maltreatment and Mental Health Outcomes among Ultra-Poor Children in Burkina Faso: A Latent Class Analysis | DoD PRF (Psychosocial RF) | OBJECTIVES: Research about the mental health of children in Francophone West Africa is scarce. This paper examines the relationships between adverse childhood experiences, including exposure to violence and exploitation, and mental health outcomes among children living in ultra-poverty in rural Burkina Faso.
METHODS: T... |
0 | Distal humeral coronal plane fractures: Management, complications and outcome | Glenohumeral Joint OA | Background: Coronal plane fractures of the distal humerus have special characteristics in classification, imaging, surgical approaches, materials used, treatment modalities, and complications. The purpose of this study is to comment on these topics. Materials and methods: A retrospective analysis was done for patients ... |
0 | Value of hip anesthesia to characterize the main origin of pain in hip-spine osteoarthritis | AAHKS (8) Anesthetic Infiltration | Background. To evaluate the value of lidocaine hip injection to determine the main origin of pain in patients with clinical and radiological evidence of hip and spine osteoarthritis. Methods. Retrospective study with a mean follow-up of 28 months. Ambulatory care patients were referred to the department for injection o... |
0 | Influence of donor age on the biomechanical and biochemical properties of human meniscal allografts | AMP (Acute Meniscal Pathology) | BACKGROUND: Although the use of meniscal allografts to replace severely damaged or absent menisci is commonplace, little is known about the effects of donor age on the biochemical and biomechanical properties of human menisci.
HYPOTHESIS: The mechanical and biochemical properties of human medial and lateral menisci fro... |
0 | Post-operative aspergillosis | Dental Implant Infection | While invasive aspergillosis occurs typically in severely immunocompromised patients, cases of surgical site infection have been reported in immunocompetent individuals. The Medline, LILACS and EMBASE databases were searched for descriptions of cases of post-operative aspergillosis, and references from relevant article... |
1 | APOLLO-2: A Randomized, Placebo and Active-Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein-Biased Ligand at the mu-Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty | Panniculectomy & Abdominoplasty CPG | OBJECTIVES: The clinical utility of conventional IV opioids is limited by the occurrence of opioid-related adverse events. Oliceridine is a novel G protein-biased mu-opioid receptor agonist designed to provide analgesia with an improved safety and tolerability profile. This phase III, double-blind, randomized trial (AP... |
0 | The financial implications of falls in older people for an acute hospital | HipFx Supplemental Cost Analysis | BACKGROUND: Falls are a common occurrence in older people and frequently lead to hospital admission. There is a current lack of cohesive fall prevention strategies in the Republic of Ireland. AIM: To demonstrate the cost of fall-related admissions to an acute hospital. METHODS: A review of Hospital Inpatient Enquiry (H... |
0 | Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review | HipFx Supplemental Cost Analysis | The aim of this review is to establish the relationship between treatment with hypnotics and the risk of postural instability and as a consequence, falls and hip fractures, in the elderly. A review of the literature was performed through a search of the MEDLINE, Ingenta and PASCAL databases from 1975 to 2005. We consid... |
0 | Profile of care given to patients with blunt chest injuries within the first 48 hours | DoD PRF (Psychosocial RF) | This study was conducted in the trauma unit of a large academic hospital in Johannesburg, South Africa. The study aimed at describing the nature of care that patients with blunt chest injuries received during the first 48 hours after injury. A descriptive survey was chosen using retrospective and prospective record rev... |
0 | Harnessing biomechanics to develop cartilage regeneration strategies | OAK 3 - Non-arthroplasty tx of OAK | As this review was prepared specifically for the American Society of Mechanical Engineers H.R. Lissner Medal, it primarily discusses work toward cartilage regeneration performed in Dr. Kyriacos A. Athanasiou's laboratory over the past 25 years. The prevalence and severity of degeneration of articular cartilage, a tissu... |
0 | Understanding the functional neuroanatomy of acquired prosopagnosia | Upper Eyelid and Brow Surgery | One of the most remarkable disorders following brain damage is prosopagnosia, the inability to recognize faces. While a number of cases of prosopagnosia have been described at the behavioral level, the functional neuroanatomy of this face recognition impairment, and thus the brain regions critically involved in normal ... |
0 | Simultaneous bilateral total knee replacement: a prospective study of 150 patients | OAK 3 - Non-arthroplasty tx of OAK | To evaluate the safety of simultaneous bilateral total knee replacement (TKR). 124 women and 26 men (mean age, 66 years) underwent simultaneous bilateral TKR for tricompartmental osteoarthritis using a posteriorstabilised, high-flexion implant. All patients underwent dobutamine stress echocardiography for detection of ... |
0 | Injured stable knee with acute effusion: MRI evaluation | AMP (Acute Meniscal Pathology) | This study was done to evaluate the magnetic resonance imaging (MRI) findings in acute traumatic effusions of the knee without ligament instability or radiographic abnormality other than the effusion. On reviewing the charts of 927 patients who had MRI of the knee, we found 114 patients who met the following criteria f... |
0 | Implications of expanding disease definitions: the case of osteoporosis | HipFx Supplemental Cost Analysis | The National Osteoporosis Foundation and American College of Obstetrics-Gynecology have expanded osteoporosis therapy recommendations by changing the treatment threshold. We determined the impact of this recommendation using nationally representative U.S. data. The new threshold changes the number of women for whom tre... |
1 | The effect of glenoid component version and humeral polyethylene liner rotation on subluxation and impingement in reverse shoulder arthroplasty | Trial Systematic Review Project | Background A previously validated finite element modeling approach was used to determine how changes in glenoid component version and polyethylene liner rotation within the humeral component affect the arm abduction angle at which impingement between the inferior glenoid and the polyethylene liner occurs as well as the... |
0 | Failure of the first step of two-stage revision due to polymicrobial prosthetic joint infection of the hip | PJI DX Updated Search | BACKGROUND: The unsuccessful treatment of prosthetic joint infection (PJI) with two-stage revision leads to infection recurrence. The objectives of the study were to assess the clinical and demographic characteristics of patients with polymicrobial PJI, and to evaluate the role of the microbial profile involved in PJI ... |
0 | Deformity correction by Ilizarov distraction osteogenesis after distal radius physeal arrest | Distal Radius Fractures | Objective: The aim of this study was to evaluate the results of osteotomy and distraction osteogenesis using Ilizarov circular external fixator to treat radial shortening and severe wrist deformity due to neglected post-traumatic distal radius physeal arrest. Methods: The study retrospectively reviewed 4 patients (4 ma... |
0 | Altered Biodistribution of <sup>99m</sup>Tc-DPD on Bone Scan After Intravenous Iron Supplement | MSTS 2018 - Femur Mets and MM | We report a case with altered biodistribution of <sup>99m</sup>Tc-dicarboxypropane diphosphonate (<sup>99m</sup>Tc-DPD) on whole body bone scan after intravenous iron supplement therapy. A 47-year-old male patient who had recently been detected with a hepatic mass suggestive of hepatocellular carcinoma underwent bone s... |
0 | Lesions of the cauda equina: a clinical and pathology review from the Armed Forces Institute of Pathology | MSTS 2022 - Metastatic Disease of the Humerus | We reviewed the clinical records of 149 patients with pathologically proved cauda equina lesions in order to define the relative frequency and clinical presentations of the various diagnoses. The most common pathology was ependymomas (47 patients) followed in frequency by nerve sheath tumors (35 patients), metastases (... |
0 | Magnetic resonance imaging abnormalities in symptomatic and contralateral knees: prevalence and associations with traumatic history in general practice | AMP (Acute Meniscal Pathology) | BACKGROUND: After trauma, internal knee lesions are found in approximately two thirds of patients. However, magnetic resonance imaging abnormalities have also been described in asymptomatic volunteers.
HYPOTHESIS: Not all visualized lesions in symptomatic posttraumatic knees are the result of recent trauma; there are s... |
0 | Effects of bisphosphonates in combination with ionizing radiation and antioxidants on the growth of prostate and melanoma cells lines | MSTS 2018 - Femur Mets and MM | BACKGROUND: Bisphosphonates are used in cancer-related hypercalcaemia, in complications of bone metastasis and in postmenopausal osteoporosis, and have often been associated with adverse complications.
AIM: To determine the protective effect of apigenin against growth inhibition of normal epithelial human prostatic (PN... |
0 | Knee Extensor Power Relates to Mobility Performance in People With Knee Osteoarthritis: Cross-Sectional Analysis | OAK 3 - Non-arthroplasty tx of OAK | BACKGROUND: Quadriceps femoris muscle strengthening is a common rehabilitation exercise for knee osteoarthritis (OA). More information is needed to determine whether targeting muscle power is a useful adjunct to strengthening for people with knee OA.
OBJECTIVE: The purpose of this study was to identify the predictive a... |
0 | New developments in the clinical use of drug-coated balloon catheters in peripheral arterial disease | DoD LSA (Limb Salvage vs Amputation) | Peripheral arterial disease (PAD) involving the lower extremity is a major source of morbidity and mortality. Clinical manifestations of PAD span the spectrum from lifestyle limiting claudication to ulceration and gangrene leading to amputation. Advancements including balloon angioplasty, self-expanding stents, drug-el... |
1 | Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk? | Reconstruction After Skin Cancer | OBJECTIVE: To determine whether the antiplatelet agent aspirin increases hemorrhagic risk in patients undergoing surgical resection of cutaneous head and neck lesions. DESIGN: Retrospective cohort study. SETTING: Regional referral center. Patients All cases of cutaneous head and neck lesions surgically resected during ... |
1 | Intramedullary nailing of open fractures of the femoral shaft | DoD SSI (Surgical Site Infections) | The cases of eighty-six patients in whom eighty-nine open fractures of the femoral shaft had been treated by intramedullary nailing with reaming were retrospectively reviewed. Twenty-seven fractures were classified as grade-I open fractures; sixteen, as grade-II open fractures; and forty-six, as grade-III open fracture... |
1 | Factors associated with infection following open distal radius fractures | DoD SSI (Surgical Site Infections) | Open fractures are often classified according to a system described by Gustilo and Anderson. However, this system was applied to open long bone fractures, which may not predict the incidence of infection in open metaphyseal fractures of the upper extremity. Other studies have found that wound contamination and systemic... |
0 | Inter-observer variation in the diagnosis of coronal articular fracture lines in the lunate facet of the distal radius | Distal Radius Fractures | BACKGROUND: Several studies support the use of CT for diagnosing coronal fractures of the distal radius but the inter-observer reliability of these observations is less well studied. We tested the null hypothesis that radiographs alone and the combination of radiographs and two-dimensional computed tomography scans (2D... |
0 | Relationship between intraoperative regional cerebral oxygen saturation trends and cognitive decline after total knee replacement: A post-hoc analysis | Surgical Management of Osteoarthritis of the Knee CPG | Background: Bilateral regional brain oxygen saturation (rSO(2)) trends, reflecting intraoperative brain oxygen imbalance, could warn of brain dysfunction. Various types of cognitive impairment, such as memory decline, alterations in executive function or subjective complaints, have been described three months after sur... |
0 | Stratifying SLN incidence in intermediate thickness melanoma patients | MSTS 2022 - Metastatic Disease of the Humerus | Background: Guidelines for melanoma recommend sentinel lymph node biopsy (SLNB) in patients with melanomas =1 mm thickness. Recent single institution studies have found tumors <1.5 mm a low-risk group for positive SLNB. Methods: A retrospective review of the Sentinel Lymph Node Working Group multicenter database identi... |
0 | Individualizing the risks and benefits of postmenopausal hormone therapy | Management of Hip Fractures in the Elderly | OBJECTIVE: The objective was to develop an individualized risk-benefit model quantifying the impact of combined use of estrogen and progestogen on chronic diseases. DESIGN: The study population consisted of women, aged 40+, prescribed postmenopausal hormone therapy (HT) in the UK General Practice Research Database (N >... |
0 | Displaced intra-articular fractures of the calcaneus: ORIF through an extended lateral approach | DoD SSI (Surgical Site Infections) | INTRODUCTION: Displaced intra-articular calcaneal fractures (DIACF) represent a challenging and controversial issue in traumatology. Conservative treatment has been recommended to avoid surgical problems and complications. The final result, however, is often a painful malunioun of the calcaneus with peroneal impingemen... |
0 | Effects of bariatric surgery for knee complaints in (morbidly) obese adult patients: a systematic review | Panniculectomy & Abdominoplasty CPG | Obesity is a major risk factor for the development of knee osteoarthritis, and over the past 30 years the prevalence of obesity has more than doubled. In an advanced-stage knee osteoarthritis is treated with total knee arthroplasty, and the demand for primary total knee arthroplasties is expected to grow exponentially.... |
0 | Neuro-Ophthalmology in Emergency Medicine | Upper Eyelid and Brow Surgery | Understanding the anatomy and physiology of the eye, the orbit, and the central connections is key to understanding neuro-ophthalmologic emergencies. Anisocoria is an important sign that requires a systematic approach to avoid misdiagnosis of serious conditions, including carotid dissection (miosis) and aneurysmal thir... |
0 | Morbidity and mortality for elderly patients with fractured neck of femur treated by hemiarthroplasty | Hip Fx in the Elderly 2019 | Patients above the age of 60 with displaced femoral neck fractures are treated by hemiarthroplasty in Singapore because of our low life expectancy. This study evaluates the morbidity and mortality of 110 such patients operated on in our department between January 1990 and December 1992. It has clinical significance bec... |
1 | Recurrent neural networks for diagnosis of carpal tunnel syndrome using electrophysiologic findings | Diagnosis and Treatment of Carpal Tunnel Syndrome CPG | This paper presents the use of recurrent neural networks (RNNs) for diagnosis of carpal tunnel syndrome (CTS) (normal, right CTS, left CTS, bilateral CTS). The RNN is trained with the Levenberg-Marquardt algorithm. The RNN is trained on the features of CTS (right median motor latency, left median motor latency, right m... |
0 | Factors associated with the quality of patients' surgical decisions for treatment of hip and knee osteoarthritis | Surgical Management of Osteoarthritis of the Knee CPG | BACKGROUND: Shared decision making requires informing patients and ensuring that treatment decisions reflect their goals. It is not clear to what extent this happens for patients considering total joint replacement (TJR) for hip or knee osteoarthritis. STUDY DESIGN: We conducted a cross-sectional mail survey of osteoar... |
0 | The morphology of proximal pole scaphoid fractures: implications for optimal screw placement | Distal Radius Fractures | The purpose of this study was to measure the radiographic parameters of proximal pole scaphoid fractures, and calculate the ideal starting points and trajectories for antegrade screw insertion. Computed tomography scans of 19 consecutive patients with proximal pole fractures were studied using open source digital imagi... |
1 | Self-reported health of Persian Gulf War veterans: a comparison of help-seeking and randomly ascertained cases | DoD PRF (Psychosocial RF) | The objective of this study was to compare self-selected Persian Gulf War veterans attending a health assessment program with veterans ascertained in an epidemiological study to determine why Gulf War veterans do, or do not, present for clinical assessment. A postal survey was sent to randomly selected United Kingdom A... |
0 | Musculoskeletal mnemonics: differentiating features | MSTS 2022 - Metastatic Disease of the Humerus | Mnemonics are often used in musculoskeletal radiology to help radiologists remember long differential diagnoses. However, unless the specific appearance of each entity on a differential is also recalled, mnemonics become useless. This article presents 8 mnemonics with their corresponding differential diagnoses and dist... |
0 | Lateral Meniscal Allograft Transplant: Dovetail Bone Bridge Preparation | AMP (Acute Meniscal Pathology) | Meniscal tears are among the most common knee injuries encountered by an orthopaedic surgeon. Once treated with total meniscectomy, meniscal preservation is now the standard of care. Not all meniscal tears are repairable, and meniscal allograft transplantation has become an integral part of the preservation algorithm. ... |
0 | Comparison of epidural analgesia with peripheral nerve blockade for bilateral knee arthroplasty - A retrospective analysis | Surgical Management of Osteoarthritis of the Knee CPG | Introduction: Even though combined femoral-sciatic blocks as part of multimodal therapy are routinely used for post-operative pain control after unilateral TKR, epidural analgesia is commonly used in patients undergoing bilateral TKR. Previous studies have shown that peripheral nerve blocks with multimodal analgesic re... |
0 | The Proximal Femur Nail Antirotation: An identifiable improvement in the treatment of unstable pertrochanteric fractures? | Management of Hip Fractures in the Elderly | BACKGROUND: The optimal surgical treatment of patients with an unstable extracapsular proximal femoral fracture is yet to be found. From the biomechanical point of view, the use of an intramedullary device in combination with a dynamic femoral head/neck stabilization implant seems an optimal technique. One of these int... |
0 | Free vascularised fibular grafting in the treatment of large skeletal defects due to osteomyelitis | Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures | Treatment of skeletal defects secondary to osteomyelitis is a challenging problem. The purpose of this study was to present our experience of the use of free vascularised fibular grafts to treat such defects. Ten patients with a mean age of 31 years (range 16-50 years) and a skeletal defect with a mean length of 9.5 cm... |
0 | The Swanson ulnar head prosthesis for post-traumatic disorders of the distal radio-ulnar joint | Distal Radius Fractures | 20 Swanson ulnar head prostheses inserted for post-traumatic disorders of the distal radio-ulnar joint were reviewed at a mean of 44.2 months post-operatively (range 12-104 months). The indication for surgery was painful loss of forearm rotation with or without ulno-carpal impingement and ulno-carpal instability. Sympt... |
0 | Meniscal transplantation in symptomatic patients under fifty years of age survivorship analysis | PJI DX Updated Search | Background: The purpose of this study was to prospectively evaluate the long-term results and survivorship of meniscal transplantation in a consecutive series of patients. Methods: Forty cryopreservedmenisciwere implanted into thirty-eight patients. Survival end points were transplant removal, revision, or tibiofemoral... |
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