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Apple-jelly nodules is/are seen in:
[ "Lupus vulgaris", "DLE", "Lichen planus", "Psoriasis" ]
A
Ans: A (Lupus vulgaris) Apple jelly nodules:characterized by yellow-brown nodules with tiny darker granules. On probing, the noduies are soft jelly-like"- Neena Khanna 3rd/217Lupus Vulgaris Neena Khanna 3rd/217MorphologySingle (or few) lesions.Well demarcated, annular or arcuate plaques which slowly extend centrifugall...
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The newly erupted tooth:
[ "Is protected by dental plaque", "Has an early immunity to caries", "Has a high affinity for fluoride", "All of the others" ]
C
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Treatment of choice for T2 carcinoma of nasopharynx is
[ "Surgery", "Radiotherapy", "Chemotherapy", "Surgery and postoperative radiotherapy" ]
B
Radiotherapy is the treatment of choice for nasopharyngeal cancer. Stage I and II are treated by radiotherapy alone while stage III and IV require concomitant radiation and chemotherapy or radiation followed by chemotherapy. External beam radiation of 6000-7000 cGy can be delivered by the linear accelerator to the prim...
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Keratometry is useful in measuring –
[ "Corneal curvature", "Corneal thickness", "Conical diameter", "Depth of anterior chamber" ]
A
Keratometry A keratometer, also known as an ophthalmometer, is a diagnostic instrument for measuring the curvature of the anterior surface of cornea. Keratometer reading provide the following information to assist in the overall assessment of the cornea:- Radii of curvature of the cornea The degree of corneal astigm...
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Caseous necrosis is not found in- rpt Q33
[ "TB", "Histoplasmosis", "CMV", "Syphilis" ]
C
Cytomegalovirus (CMV) ) is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. Humans and monkeys serve as natural hosts. There are currently eight species in this genus including the type species, human cytomegalovirus (HCMV, human herpesvirus 5, HHV-5), whic...
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Open reduction in children is required for
[ "Fracture both bones of forearm", "Femoral condyles", "Lateral humeral condyle", "Distal tibial epiphysis" ]
C
C i.e. Lateral Condyle fr
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Drug contra-indicated in HOCM is: March 2011
[ "Verapamil", "Propranolol", "Digoxin", "Amiadarone" ]
C
Ans. C: Digoxin Digoxin and vasodilators may increase outflow tract obstruction and should be avoided in HOCM
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The buffer with the highest pKa is:
[ "Phosphate", "Bicarbonate", "Intracellular proteins", "Ammonia" ]
D
Buffer PKa Phosphate 6.8 Bicarbonate 6.1 Intracellular proteins 7.2 Ammonia 9.0 The only basic buffer is ammonia.
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Optical urethroplasty is done in:(Internet)
[ "Congenital stricture of urethra", "Hypospadias", "Epispadias", "Testicular tumour's" ]
A
(Congenital stricture of urethra) (1388-89-Baily & Love 24th) (Internet) (1362-Baily & Love 25th)Hypospadias - surgical plastic repair of hypospadias is currently accomplished by a variety of highly successful one stage operations and is routinely performed between 6 and 19 months of age (1008-CSDT 12(tm))Epispadias - ...
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All of the following are released/increased in surgical stress EXCEPT:
[ "ADH", "Insulin", "ACTH", "Cortisol" ]
B
Ans. (b) InsulinRef: Bailey & Love 26th ed. /4* The stress response to surgery is characterized by increased secretion of pituitary hormones and activation of the sympathetic nervous system. Release of corticotrophin from the pituitary stimulates cortisol secretion from the adrenal cortex. Arginine vasopressin is secre...
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All are causes of acute tubulointerstitial nephritis except:
[ "Methicillin", "Sjogren syndrome", "SLE", "Down's syndrome" ]
D
Acute Tubulointerstitial Disorders Therapeutic agents Antibiotics (Beta-lactams, sulfonamides, quinolones, vancomycin, erythromycin, minocycline, rifampin, ethambutol, acyclovir) Nonsteroidal anti-inflammatory drugs, COX-2 inhibitors Diuretics (rarely thiazides, loop diuretics, triamterene) Anticonvulsants (phenytoin...
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Incisional biopsy of a breast mass in a 3 5-year-old woman demonstrates a hypercellular fibroadenoma (Cystosarcoma phyllodes) at the time of frozen section. Appropriate management of this lesion could include
[ "Wide local excision with a rim of normal tissue", "Lumpectomy and axillary lymph- adenectomy", "Modified radical mastectomy", "Excision and postoperative radiotherapy" ]
A
Cystosarcoma phyllodes is a tumor most often seen in younger women. It can grow to enormous size and at times ulcerate through the skin. Still, it is a lesion with low propensity toward metastasis. Local recurrence is common, especially if the initial resection was inadequate. Simple re-excision with adequate margins i...
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'Syndrome of apparent mineralocoicoid excess' is due to deficiency of
[ "11a--hydroxysteroid dehydrogenase", "11b--hydroxysteroid dehydrogenase", "12a--hydroxysteroid dehydrogenase", "12b--hydroxysteroid dehydrogenase" ]
B
Syndrome of apparent mineralocoicoid excess is due to genetic deficiency of 11b-dehydrogenase-2, cause hypokalemia. Liddle's syndrome is caused by autosomal dominant gain-in-function mutations of ENaC subunits, cause hypokalemia. Loss of the transpo functions of the thick ascending loop of Henle and distal convoluted t...
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Iodine 123 has a half life of?
[ "6 hours", "8 days", "13 hours", "14 days" ]
C
Impoant Radioisotopes Half Life RADIOISOTOPE HALF LIFE IODINE 131 8 DAYS IODINE 125 60 DAYS IODINE 124 4 DAYS IODINE 123 13 HOURS PHOSPHORUS -32 14 DAYS RADIUM (RA-226) 1622 years Cobalt -60 5.2 years Cesium - 137 30 years TC- 99m 6 hours Iridium (Ir-192) 74.5 Days 18F (18FDG) 110 min Strontium 89 50.5 days
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Cytokines:
[ "Includes interleukins", "Produced only in sepsis", "Are simple proteins", "Have highly specific action" ]
A
null
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Major apolipoprotein of chylomicrons -
[ "B-100", "D", "B-48", "None" ]
C
Ans. is 'c' i.e., B-48 TypeFound inSite of synthesisFunctionApo-A AI-IHDL, Chylomicrons QLiver, intestineMajor structural protein of HDL Q, major activator of LCAT Q -A-IIHDL, ChylomicronsLiver, intestineStructural protein of HDL, inhibits lipoprotein lipase (LPL), stimulate hepatic lipase, inhibits LCATA-IVHDL, Chylom...
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Which of the following is true about CLL treatment-
[ "Should be offered to all patients", "Can be withheld in asymptomatic patients", "Is curative", "Combination chemoradiotherapy should be given in patients above 50 years age" ]
B
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Proliferation of nasal masses in Rhinoscleroma produces characteristic configuration typical of the disease
[ "Hebra nose", "Scrofula", "Nose root deformity", "Mongolian nose" ]
A
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During abutment preparation for overdenture, which of the following is more preferable?
[ "Short copings", "Long copings", "Bare root surface", "None of the above" ]
C
A bare root surface can provide adequate long term service for both immediate and replacement overdentures and is the selection of choice.
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AML with worst prognosis
[ "8/21 translocation", "Inversion 16", "Normal cytogenetics", "Monosomy 7" ]
D
AMLs with t (15;17)have best prognosis. AMLs with t (8;21)or inv (16) have relatively good prognosis with conventional chemotherapy. Poor prognosis for AMLs that follow MDS or genotoxic therapy or that occurs in adults. AMLs following MDS or exposure to DNA damaging agents have deletions or monosomies involving chromos...
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The pain in the lateral thigh and pubic regions continues to be intense and unremitting. The patient is admitted to the hospital for observation and possible surgical intervention. Given this paicular pattern of renal colic and the anatomy of the renal system, it is suspected that a stone has stopped moving and is lodg...
[ "At the junction of the renal pelvis and ureter", "Midureter as it passes beneath the gonadal vessels", "At the pelvic brim", "In the intramural poion of the ureter where it penetrates the bladder" ]
C
The ureters narrow at the renal pelvis, at the pelvic brim, where they cross the iliac vessels and enter the deep pelvis, and at the urinary bladder. Thus, the probability of a nephrolith lodging in the ureter at the pelvic brim is high and is confirmed by the pattern of referred pain.
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Which antimalarial drug is known to cause neuropsychiatric reaction as its adverse effect?
[ "Artesunate", "Artimisnin", "Quinine", "Mefloquine" ]
D
Ans. d. Mefloquine (Ref H-17th/1288).Acute reversible cognitive dysfunction and neuropsychiatric reaction manifested by confusion, psychosis, convulsions, or encephalopathy is a S/E known with Mefloquine. Approximately 1 in every 10,000 recipients develops it.MEFLOQUINE# Mefloquine (250 mg of salt weekly, adult dose) h...
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All are seen in ARDS, except :
[ "Pulmonary edema", "Decreased tidal volume", "Hypercapnia", "Decreased compliance" ]
C
Answer is C (Hypercapnia): ARDS results in Type I Respiratory failure and is characterized by normal or low PaCO2 (Hypocapnia) and not Hypercapnia (see previous explanation on types of respiratory failure). ARDS (Acute Respiratory distress syndrome) ARDS is an acute form of lung injury characterized by: Increased perme...
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A boy presents with erythematous scaly papules with crusting over on antecubital fossa. He was applying petroleum based emollient in the shower. What is the next step in management?
[ "Decrease the frequency of petroleum", "Decrease the frequency of shower", "Mupirocin 1% topical application", "Triamcinolone cream topical application" ]
D
D i.e. Triamcinolone cream topical applicationRef: Rook's Textbook of Dermatology, 8th edition, page 24.20Explanation:The given history of erythematous scaly papules with crusting over antecubital fossa in a boy is suggestive of a diagnosis of atopic dermatitis. The fact that he was advised emollient in shower also sug...
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A 37-year-old man with AIDS presents with confusion, lethargy and memory loss. CT of the brain demonstrates multiple supratentorial enhancing masses. Which imaging feature ours a diagnosis of toxoplasmosis rather than primary CNS lymphoma?
[ "Subependymal Distribution", "Lesions Hyperdense On Unenhanced CT", "Lesion Size >3 Cm", "Lesions without increased tracer activity on FDG-18 PET imaging" ]
D
Cerebral toxoplasmosis must be differentiated from other oppounistic infections or tumors in the CNS of AIDS patients. The differential diagnosis includes herpes simplex encephalitis, cryptococcal meningitis, progressive multifocal leukoencephalopathy, and primary CNS lymphoma. Toxoplasmosis - Noncontrast CT scans show...
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Creatinine is synthesized from -
[ "Arginine", "Alanine", "Histidine", "Cysteine" ]
A
Ans. is 'a' i.e., Arginine o Creatinine is synthesized from arginine, glycine and methionine.o Creatine and creatinine are not amino acids, but specialized products of amino acidso Creatine is synthesized from glycine, arginine and methionine.o Synthesis start with formation of guanidoacetatefrom glycine and arginine i...
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Semen examination of a man showed counts of 25 million/cu.mm, volume - 1.5 ml; motility - 15%; Morphology - 15%. What is the diagnosis?
[ "Azoospermia", "Asthenospermia", "Oligospermia", "Teratospermia" ]
B
World Health Organization reference values: Semen volume: 1.5 ml or more pH: 7.2-7.8 Sperm concentration: 15 million spermatozoa per ml or more Total sperm number: 39 million spermatozoa per ejaculate or more ( Range 36-42 million /ml) Total motility : 40% or more motile or 32% or more with progressive motility Round c...
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patient in the emergency department exhibits psychosis. Pharmacological intervention to decrease the psychosis would most likely involve:
[ "Blockade of dopaminergic neurotransmission", "Stimulation of dopaminergic neurotransmission", "Blockade of nitrergic neurotransmission", "Stimulation of nitrergic neurotransmission" ]
A
Ans. A. Blockade of dopaminergic neurotransmissionDopamine plays a major role in two functional systems of the brain, the motor system and the limbic system. Within the limbic system, DA is associated with affect. Too much dopaminergic transmission can result in psychotic disorders, such as schizophrenia. A blockade of...
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Sterile hemorrhagic cystitis is caused by :
[ "Busulfan", "Ketoprofen", "Methicillin", "Cyclophosphamide" ]
D
null
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Progressive multifocal leukoencephaloPathy is caused-
[ "Epstein-barr virus", "Varicella-zoster virus", "Cytomegalo Virus", "JC Papovavirus" ]
D
Harrison's principles of internal medicine. *In PML oligodendrocytes have enlarged densely staining nuclei that contain viral inclusions formed by crystallinearrays of JC virus paicles.
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A man developed a pustule after striking by a thorn in the garden. Laboratory examination of the tissue specimen shows cigar-shaped budding yeasts. Most probable causative agent is:
[ "Sporothrix", "Sporotrichosis", "Phialophora", "Aspergillus" ]
A
Sporothrix schenckii, is a dimorphic fungus. The mold form lives on plants and the yeast form occurs in human tissue. When spores of the mold are introduced into the skin, typically by a thorn, it causes a local pustule or ulcer with nodules along the draining lymphatics. In the clinical laboratory, round or cigar-shap...
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Mechanism of action of furosemide as a diuretic is:-
[ "Inhibition of Na-K-Cl ion sympoer", "Aldosterone antagonism", "Inhibition of Na-Cl sympoer in distal tubules", "Carbonic anhydrase inhibition" ]
A
Name Site of action Example Mechanism Loop diuretics Thick ascending limb of Loop of Henle Furosemide, Torsemide Na-K-2Cl sympoer inhibition Carbonic anhydrase inhibitors PCT Acetazolamide, Dorzolamide, Brinzolamide Carbonic anhydrase inhibition Thiazides DCT Hydrochlohiazide, Chlohalidone Na-Cl sympoer inhibition Osmo...
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Tenderness is uncommon in –
[ "Herpes genitalis", "Chancroid", "Donovanosis", "All of the above" ]
C
Pain & tenderness  →  HSV, Chancroid Painless & without tenderness →  LGV, donovanosis, chancre.
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Newborn with APGAR score of 2 at 1 min. & 6 at 5 min. has respiratory distress & mediastinal shift diagnosis is -
[ "Congenital adenomatoid lung disease", "Pneumothorax", "Diaphragmatic hernia", "All" ]
D
Ans. is 'a' i.e., Congenital adenomatoid lung disease; 'b' i.e., Pneumothorax & 'c' i.e., Diaphragmatic hernia Causes of respiratory distress with mediastinal shift in neonates ? o Diaphragmatic hernia o Congenital mediastinal mass o Congenital cystic adenomatoid malformation o Congenital lobar emphysema o Pneumothorax
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Which of the following is an impoant tumour marker in the diagnosis of endodermal sinus tumour: March 2011
[ "HCG", "Ca-125", "LDH", "Alpha FetoProtein" ]
D
Ans. D: Alpha Feto Protein Endodermal sinus (yolk sac) tumour is thought to originate from a multiple potential embryonal tissue as a result of selective differentiation of yolk sac structures. This explains why the tumour is rich in alpha-fetoprotein and alphal antitrypsin
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A pure tone audiogram with a dip at 2000 Hz is characteristic of-
[ "Presbyacusis", "Ototoxicity", "Otosclerosis", "Noise induced hearing loss" ]
C
Dip at 2000 Hz in PTA called as carharts notch is characteristic of otosclerosis.
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A 40-year-old woman presents with a painless mass anterior to her left ear. The mass had been slowly enlarging over the past year. The mass is firm and nontender. Computed tomography and magnetic resonance imaging reveal a well-circumscribed, homogeneous mass within the left parotid gland. Biopsy reveals anastomosing s...
[ "It is also called papillary cystadenoma lymphomatosum.", "It is most often localized to the submandibular gland", "It is the most common malignant salivary gland tumor.", "Recurrence often takes place after surgical resection" ]
D
Pleomorphic adenoma/ Mixed tumor. - Approximately 80% to 90% of salivary gland tumors originate in parotid gland & of these, approximately 70% are pleomorphic adenomas. - The term "mixed tumor" properly applies to this benign tumor, which often demonstrates myxoid & cailage-like elements in addition to stellate or fusi...
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Secondary deposits from prostatic carcinoma is commonest in
[ "Bone", "Kidney", "Liver", "Brain" ]
A
null
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Most common cause of pathological jaundice on first day of life is: March 2008
[ "Physiologic", "Biliary atresia", "Rh incompatibility", "Sepsis" ]
C
Ans. C: Rh Incompatibility Hyperbilirubinemia in the first week of life is usually of the indirect variety. Causes of hyperbilirubinemia appearing within 24 hours of age: Hemolytic disease of newborn: Rh, ABO and minor group incompatibility Infections: intrauterine viral, bacterial; malaria G-6PD deficiency
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Which of the following denotes the trend of events that pass with time?
[ "Frequency polygon", "Histogram", "Line chart", "Pie diagram" ]
C
Ans. c (Line chart) (Ref. Text book of biostatistics by B K Mahajan, Vlth /pg. 20; Park PSm 22nd/788)Line diagrams are used to show the trend of events with the passage of time.Type of dataQualitative dataQuantitative dataDefinitionCharacteristics same, only frequency variesCharacteristics as well as frequency both var...
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In random sampling chance of being picked up is-
[ "Same and known", "Not same and not known", "Same and not known", "Not same but known" ]
A
.
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Which vaccine gives herd immunity
[ "OPV", "Typhoid", "Cholera", "None" ]
A
If the herd immunity is sufficiently high the occurrence of an epidemic is regarded highly unlikely. If that level of immunity is maintained and stepped up by an ongoing immunization programmed to the point where the susceptible populations are reduced to a small propoion of the population. This has been achieved in di...
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True combination is all except –
[ "Cold–Trench foot", "Light–Miner's nystagmus", "Pressure–Caisson disease", "Cane fibre–Farmer's lung" ]
D
null
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In cyclo-propagative transmission, the disease agent undergoes
[ "Only development", "Only multiplication", "Change in form and numbers", "No change" ]
C
Biological transmission of vector borne diseases: Cyclo-Propagative : The agent changes in both form and number, eg: Malaria parasite in mosquito Propagative : The agent merely multiplies in vector, but no change in form, eg: Plague bacilli in rat fleas Cyclo-Developmental : The disease agent undergoes only development...
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Features seen in common peroneal nerve injury:
[ "Inversion inability", "Loss of sensation of sole", "Foot drop", "All" ]
C
C i.e. Foot drop- Common peroneal nerve injury (usually d/t fracture of head/neck fibula)Q results in foot & toe drop, loss of dorsiflexion of ankle, extension of finger and eversion of foot and loss of sensation in 1st web space, and anterolateral lower leg & dorsum of foot and toes.- In common peroneal nerve injury s...
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In atrial septal defect the aoa is
[ "Small", "Normal", "Enlarged", "Aneurysmal" ]
A
In ASD chest xray shows small aoic shadow. Ref : Ghai essential of pediatrics,eighth edition, P.no: 413
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Pain sensations from the ethmoidal sinus are carried by-
[ "Frontal Nerve", "Lacrimal Nerve", "Nasocilliary Nerve", "Infra orbital Nerve" ]
C
As discussed in preceeding text, nasociliary nerve–branch of opthalmic division of trigeminal nerve carries pain sensation from ethmoid sinus.
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Which of the following statements is true about Rectal atresia?
[ "Usually a fistula is present with the urethra or bladder", "Anus is usually normal", "Stricture of the rectum", "Common type of anorectal malformation" ]
B
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Which of the following is not seen in Ehlers-Danlos syndrome?
[ "Kyphoscoliosis", "Ahrochalasia", "Dermatosparaxis", "Pectus excavatum" ]
D
Classification of Ehlers-Danlos syndrome (EDS) Classic (types I/II) - Skin and joint hypermobility, atrophic scars, easy bruisingHypermobility (type III) - Joint hypermobility, pain, dislocations Vascular (type IV) - Thin skin, aerial or uterine rupture, bruising, small joint hyperextensibilityKyphoscoliosis (type VI E...
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Pure gold fuses at the temperature (in °C) of:
[ "863", "1063", "1263", "1463" ]
B
null
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Histology of Alpo syndrome -
[ "Foamy cells in interstitium", "Foamy cells in tubular epithelial cells", "Thickening of GBM > 100 nm", "All" ]
A
Ans. is 'a' i.e., Foamy cells in interstitiumHistological characteristics of Alpo - syndrome :o Diffuse basement membrane thinningo Foam cell in interstitium -4 Due to accumulation of neutral fat and mucopolysaccharideo In advanced stage there is focal or global glomerulosclerosis.o Vascular sclerosiso Tubular atrophyo...
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Following is/ are the clinical feature/ s of lepromatous leprosy -
[ "Leonine facies", "Loss of libido and impotence", "Saddle nose", "All the above" ]
D
Ans. is 'd' i.e., All the above Important clinical features oflepromatous leprosyo Diffuse erythema, tingling, nasal stuffiness or ep is tax is are earliest manifestations.o Nodules with predeliction for external ears,o Madarosis (loss of eye lashes and eye brow s),o Saddle nose (Collapse of nasal bridge) and perforati...
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Which of the following laryngeal muscles is supplied by the external laryngeal nerve?
[ "Posterior cricoarytenoid", "Lateral cricoarytenoid", "Cricothyroid", "Thyroarytenoid" ]
C
External laryngeal nerve only supplies cricothyroid muscle. Notes: Recurrent laryngeal nerve supplies posterior cricoarytenoid, lateral cricoarytenoid, transverse and oblique arytenoid, aryepiglottic, thyroarytenoid, thyroepiglottic muscles. It supplies all intrinsic muscles except cricothyroid. During thyroidectomy, t...
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Irreversible cell injury is indicated by -
[ "Accumulation of calcium in mitochondria", "Myelin figures", "ATP depletion", "Shifting of ribosomes" ]
A
Ans. is 'a' i.e., Accumulation of calcium in mitochondrion Large, flocculant, amorphous densities in mitochondrial matrix develop due to increased Ca+2 influx. Note : o Small (not large) phospholipid rich amorphous densities are found in reversible injury.
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All are risk factors for carcinoma endometrium EXCEPT : All are risk factors for carcinoma endometrium EXCEPT :
[ "Multiple sexual paners", "Diabetes", "Hypeension", "Infeility" ]
A
Multiple sexual paners
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Better prognostic factor for operation of biliary duct obstruction in newborn are -a) No passage of bileb) Size of ductule > 200 micronc) Weight of baby > 3 kgd) Preterm babye) Age of 8 weeks
[ "ab", "be", "bc", "ce" ]
B
null
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Gutter fracture of skull results from
[ "Injury with a round object", "Bullet injuries", "Automobile accident", "Falling from height" ]
B
Gutter fractures: They are formed when pa of the thickness of the bone is removed so as to form a gutter e.g. oblique bullet wound. Ref - Krishnan Vij 5th edition pg 156 ,275
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All of the following are true about Lymphoma of the thyroid except:
[ "More common in females", "Slow growing", "Clinically confused with undifferentiated tumours", "May present with respiratory distress and dysphagia" ]
B
Lymphoma of the thyroid is a rapidly growing malignancy similar to anaplastic carcinoma. Sabiston writes - "This diagnosis should be considered in patients who present with a goitre, especially one that has apparently grown significantly in a short period." Lymphoma Lymphoma is a rare malignancy of thyroid (< 1%). Mos...
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Nowadays radium is not used in the Rx of cancer because:
[ "It decays faster and needs frequent replacement", "It decays into daughter Radon which is a constant hazard", "It has a very long half life", "It is a very unstable element" ]
B
Ans. It decays into daughter Radon which is a constant hazard
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Caudal regression syndrome is seen in babies of mother having :
[ "Gestational diabetes", "PIH", "Cardiac disease", "Anaemia" ]
A
Caudal regression syndrome or sacral agenesis is the congenital defect which is 200 times specific to diabetes. It is a fetal complication of maternal diabetes TEXT BOOK OF OBSTETRICS,Sheila Balakrishnan,2nd edition,page no.243
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Vitamin K is involved in the post-translational modification of?
[ "Glutamate", "Aspartate", "Glycine", "GABA" ]
A
Ans. (A) Glutamate(Ref Katzung 11/e p595)Vitamin K causes gamma carboxylation of glumate residues in many clotting factors that result in their activation.
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The following is not a features of Alzheimer's disease
[ "Neuro fibrillory tangles", "Senile (neuritic) plaques", "Amyloid angiopathy", "Lewy bodies" ]
D
Lewy bodies are commonly found in Parkinsonism.
train
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Which of the following most commonly cause intraorbital metastasis in female :
[ "Breast cancer", "Cervical cancer", "Ovarian cancer", "Endometrial cancer" ]
A
Carcinoma breast cause metastasis in both bone and soft tissues. Brain secondaries may leads to intraorbital metastasis. For more information refer page no 558 of SRB'S manual of surgery ,5 th edition.
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A baby assessed 5 minutes after birth is found to be blue with irregular gasping respiration. Heart rate ( HR) is 60 beats/min , and a grimace is seen with some flexion of extremities. The Apgar score for this newborn is​:
[ "0", "2", "3", "4" ]
D
In this baby,​ color, blue : score 0​ heart rate <60 beats/min: score 1​ Grimace: score 1​ Some flexion of extremities: score 1​ Irregular respiration: score 1​ Note: ​ A- Appearance​ P-Pulse​ G-Grimace​ A-Activity​ R-Respiration​ APGAR Scoring System
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Which one of the following sequence is not expressed in a mature messenger RNA of a segment of a eukaryote gene?
[ "Intron", "Exon", "Plasmid", "TATA box" ]
A
In eukaryote organisms, a structural gene usually consists of several coding regions which are known as exons that are separated by non-coding regions which are introns / intervening sequences. They do not express. Ref: Human Molecular Biology: An Introduction to the Molecular Basis of Health and Disease, 2003, Page 41
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Formation of gall stones occurs in all EXCEPT
[ "OCP users", "Ileal resection", "Jejunum resection", "Choletyramine therapy" ]
C
i.e. (Jejunum resection): (1120-Bailey & Love 25th) (552-CSDT 13th) (1993-H17th)Predisposing factors for cholesterol and pigment gall stone formationCholesterol Stones1. Demographic / genetic factors - highest in north americans and lowest in Japan, familial disposition hereditary aspects2. Obesity : Normal bile acid p...
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Non Parametric tests among the following:
[ "Mann Whitney test", "Student t-test", "Pearson correlation", "ANOVA" ]
A
null
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Acanthosis nigrans is most common due to carcinoma of:
[ "Bronchus", "Breast", "Colon", "Testis" ]
A
Bronchus
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Treatment of choice for placental site trophoblastic disease is -
[ "Observation", "Surgery", "Chemotherapy", "Radiotherapy" ]
B
Ans. is 'b' i.e., SurgeryPlacental Site Trophoblastic TumorArises from the placental bed trophoblasts and invades the myometrium.Most of these tumors run a benign course, malignancy is rare.Tumor is resistant to chemotherapy.Hysterectomy is the recommended treatment.
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Ethambutol is associated with
[ "Red-green colour blindness", "Red-blue colour blindness", "Blue-green colour blindness", "Yellow-green colour blindness" ]
A
Ethambutol may cause ‘optic neuritis’ (ocular toxicity): 463 National Health Programmes, Policies and Legislations in IndiaReview of Preventive and Social Medicine It may lead to ‘red-green color blindness’ Patients may thus develop ‘blue vision’ Thus it is contraindicated in children < 6 years age, as they may not be ...
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Trophoblast gives rise to all the following EXCEPT?
[ "Cytotrophoblast", "Syncytiotrophoblast", "Intra-embryonic mesoderm", "Extra-embryonic mesoderm" ]
C
Around day 6 - 8 after feilization : 1. Outer cell mass i) Cytotrophoblast ii) Syncytiotrophoblast 2. Inner cell mass of embryoblast i) Epiblast ii) Hypoblast Intraembryonic mesoderm is formed from epiblast cells.
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A 48-year-old man presents with recurrent headaches and ahritic pain in his knees of 9 months in duration. He notes that his head size has recently increased. Physical examination reveals a blood pressure of 170/100 mm Hg. The patient is observed to have coarse facial features and a goiter. Urinalysis reveals glucosuri...
[ "Excess growth hormone secretion", "Excess parathyroid hormone secretion", "Excess prolactin secretion", "Hypersecretion of bone morphogenetic protein" ]
A
- Given clinical features are suggestive of Acromegaly; which is d/t increased growth hormone, produced by pituitary adenomas. - C/F of Acromegaly: Enlargement of terminal poions of extremities & jaw Headaches and visual disturbances d/t compression on optic chiasma. Menstrual irregularities in women Diabetes mellitus....
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Which among the following is associated with thrombocytopenia?
[ "Gray platelet syndrome", "Glanzmann thrombasthenia", "Bernard soulier syndrome", "Storage pool disease" ]
C
Bernard soulier syndrome is a congenital bleeding disorder characterised by thrombocytopenia with giant platelets and prolonged bleeding time. The cause for platelet dysfunction in Bernard soulier syndrome is the severe deficiency or absence of the VWF receptor (GPIb complex) on the platelet membrane. Ref: O P Ghai, 5t...
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Continuous Renal Replacement Therapy is initiated in which of the following phases of Acute Renal Failure:
[ "Initiation", "Maintenance", "Diuretic Phase", "Recovery Phase" ]
B
Answer is B (Maintenance) Continuous Renal Replacement Therapy should be initiated during the Maintenance phase (Oliguric Phase) of Acute Renal Failure. Maintenance phase refers to the phase of Renal Failure in which the renal injury becomes established. It is also known as the Oliguric Phase. During this phase the GFR...
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100 people of viral fever are treated with a medicine 94 percent were cured in 5-7 days. True statement about efficieny of medicine-
[ "Medicine is effective", "Cannot be commented", "Medicine is ineffective", "None of the above" ]
B
.
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NOT True about otosclerosis
[ "Females more common than males", "Leads to Unilateral deafness", "Tympanic membrane is Normal", "Occurs at Oval window" ]
B
It is Bilateral condition.
train
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Modiolus at the corner of mouth is formed by all of the following muscles except
[ "Triangularis", "Buccinator", "Masseter", "Orbicularis oris" ]
C
null
train
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Before conducting the inquest, police should inform: MAHE 10
[ "Director general police", "Sessions Judge", "Executive Magistrate", "Senior police officer" ]
C
Ans. Executive Magistrate
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Beta-Oxidation is peroxisome is differentiated from that occurring in mitochondria by:
[ "Acetyl CoA", "H202 formed", "Different enzymes are found in different sites", "NADH is required" ]
B
B i.e. H202 formed
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Which of the following is not affected by saliva?
[ "Impression plaster", "Impression paste", "Silicon impression material", "None of the above" ]
D
null
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All of the following are present in lateral sulcus except:
[ "Middle cerebral artery", "Superficial middle cerebral vein", "Deep middle cerebral vein", "Great cerebral vein" ]
D
Ans. D. Great cerebral veinGreat cerebral vein of Galen is formed by the union of two internal cerebral veins, which run around the brain stem.
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Most common site of metastases in neuroblastoma
[ "Lung", "Liver", "Skull", "Vertebrae" ]
C
metastases in neuroblastoma :  Most commonly involved organs are lymph nodes, long bones, skull, bone marrow, liver.
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Which of the following is an inducer of microsomal enzymes:
[ "Phenobarbitone", "Paracetamol", "Digoxin", "Penicillin" ]
A
null
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A young person is having comedones and papulopustular acne over face and trunk and back. How will you manage the patient ?
[ "Topical retinoic acid", "Oral doxycycline + topical retinoic acid", "Topical clindamycin", "Oral retinoic acid" ]
B
systemic antibiotics are mainstay in the Rx of acne vulgaris. Tetracycline group is commonly prescribed of which more lipophilic antibiotics like doxycycline and minocycline are more effective. Topical Retinoids are comedolytic and anti inflammatory. They act by restoring the altered follicular keratinisation. Grade 1 ...
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Valve of Hasner is present at
[ "Stensons duct", "Common bile duct", "Naso lacrimal duct", "Maxillary Sinus" ]
C
null
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Diagnostic test for corneal ulcer: March 2005
[ "Methylene blue", "Sodium fluorescein dye", "Alcian blue", "Rose Bengal" ]
B
Ans. B: Sodium fluorescein dyeDirect observation under magnified view of slit lamp may reveal the ulcer on the cornea.Fluorescein stain is taken up by exposed corneal stroma and appears green and it helps in defining the margins of the corneal ulcer, and can reveal additional details of the surrounding epithelium.Herpe...
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The Z DNA helix
[ "Has fewer base pairs per turn than B DNA", "Is ored by an alternating GC sequences", "Tends to be found at 3 end to genes", "Is inhibited by methylation of the bases" ]
B
Z-DNA is one of the many possible double helical structures of DNA. It is a left-handed double helical structure in which the double helix winds to the left in a zig-zag pattern (instead of to the right, like the more common B-DNA form). Z-DNA is thought to be one of three biologically active double helical structures ...
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Which is not a function of PHC-
[ "Medical care", "Referral services", "Advanced Laboratory services", "MCH" ]
C
Functions of PHC includes ; - medical care - MCH - Safe water and sanitation - health education - referral services - training of health guide, health workers - basic laboratory services Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no;905 <\p>
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All are true regarding retinoblastoma except:
[ "They play major role in cell cycle regulation", "Require deletion of both the Rb genes", "Familial variant is autosomal dominant in inheritance", "Chromosome 13p 14" ]
D
Rb gene aka "Governor of the cell cycle" is a key negative regulator of the G1/S cell cycle transition. Rb gene is located on 13q14 chromosome. To explain the two patterns of occurrence of retinoblastoma, Knudson proposed his now canonic "two hit" hypothesis of oncogenesis. Two mutations (hits), involving both alleles ...
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A person get infected in a hospital and clinical manifestation appear after he is discharged this is called -
[ "Nosocomial infection", "Oppounistic infection", "Epizootic infection", "Physician induced" ]
A
Ans. is 'a' i.e., Nosocomial infection . The term hospital infection, hospital -acquired infection or nosocomial infection are applied to infections developing in hospitalized patients, not present or in incubation at the time of their admission. . Such infections may become evident during their stay in hospital or, so...
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Burtonian line is seen in poisoning:
[ "Lead", "Arsenic", "Copper", "Silver" ]
A
Chr. Lead poisoning = Plumbism = Saturnism = Saturnine poisoning- ALA in urine, Coproporphyrin in urine, facial pallor, Basophilic stippling/Punctate basophilia (dark blue, pin-head spots in cytoplasm of RBCs), Burtonian line (blue line gums' margin, PbS, 50-70% cases, near carious/dirty teeth, Lead palsy, Pb encephalo...
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Careless handling of a suspected case of cervical spine injury may result in:
[ "Injury to the spinal cord leading to quadriparesis or quadriplegia", "Intracranial haemorrhage with cerebral imtation or unconsciousness", "Cervical haematoma with compression of brachial vessels", "Complete paralysis of the affected upper extremity" ]
A
A i.e. Injury to the spinal cord leading to quadriparesis or quadriplegia
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Which one of the following is an adverse effect associated with combined oral contraceptives:
[ "Cerebral stroke", "Aggravation of asthma", "Peripheral neuropathy", "Nephrotic syndrome" ]
A
null
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Reaction of the tooth to trauma include
[ "Pulpal hyperemia", "Internal hemorrhage", "Internal resorption", "All of the above" ]
D
null
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A middle aged old female presents to surgical OPD with thyroid swelling. She has been treated for Hodgkin's lymphoma. Which of the following thyroid malignancy is most likely to be suspected in this patient?
[ "Papillary thyroid cancer", "Medullary thyroid cancer", "Anaplastic thyroid cancer", "Thyroid lymphoma" ]
A
Given history of treatment of Hodgkin's lymphoma most likely raises a suspicion of Papillary carcinoma of thyroid because of the radiotherapy used in the treatment of Hodgkin's lymphoma. Papillary carcinoma of thyroid: MC among thyroid malignancy Commonly seen in iodine sufficient areas Low dose radiation exposure duri...
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What is true about HER2/neu overexpression in Ca breast:
[ "Good prognosis", "Responds well to taxanes", "Responds well to monoclonal antibodies", "Seen only in breast cancer" ]
C
null
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Parametric test are all except:
[ "Chi-square test", "Z test", "Paired test", "Pearson correlation" ]
A
null
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The hepatic poal vein is formed by the union of which of the following major vessels?
[ "Superior Mesenteric and Inferior Mesenteric Veins", "Superior Mesenteric and Splenic Veins", "Superior Mesenteric And left renal vein", "Inferior Mesenteric and Splenic Vein" ]
B
The hepatic poal vein is formed by the union of, (a) Splenic vein, which drains the spleen, pancreas, greater curvature of stomach, and (b) Superior mesenteric, which drains the small intestine andascending colon. The gastric vein, which drains the lesser curvature of the stomach, empties directly into the hepatic poal...
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Ecthyma gangrenosum seen in?
[ "Pseudomonas septicemia", "Lepromatous leprosy", "Ulcerative colitis", "All of the above" ]
A
Ecthyma Deeper variant of impetigo Indurated lesion with necrotic crust=on removal=forms ulcer Three types Ecthyma gangrenosum - Pseudomonas aeruginosa Ecthyma pyogenicum - Strep, Staph aureus Ecthyma contagiosum / Contagious pustular disease / Orf disease - Parapox virus/ORF virus. It is zoonotic viral condition which...
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Superior wall of middle ear is formed by
[ "Tympanic membrane", "Jugular bulb", "Tegmen tympani", "None" ]
C
Ref BDC volume3,sixth edition The relations are: FLOOR-Internal jugular vein ROOF-Tegmen tympani ANTERIOR WALL-Internal carotid aery, canal for tensor tympani, tubal opening POSTERIOR WALL-Facial canal, aditus to antrum MEDIAL WALL-Oval window, round window, pyramid, tympanic plexus, promontory LATERAL WALL-Malleus, in...
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