question
stringlengths
1
6.54k
choices
listlengths
4
4
answer
stringclasses
4 values
rationale
stringlengths
0
22.5k
split
stringclasses
1 value
dataset
stringclasses
6 values
subject
stringclasses
1 value
Resolution of physiological umbilical hernia occurs at which week of gestation?
[ "6", "8", "10", "12" ]
C
ANSWER: (C) 10REF: Abdominal Wall Hernias: Principles and Management By Robert Bendavi page: 594During development the intestinal loops lie outside the abdominal cavity in the umbilical cord called the physiological umbilical hernia. The loops go back into the abdominal cavity by 10th week of gestation.
train
med_mcqa
null
Which nerve is involved?
[ "Long thoracic Nerve", "Musculocutaneous nerve", "Lateral anterior thoracic nerve", "Thoracodorsal nerve" ]
A
Ans. (a) Long Thoracic NerveNerve involvedMuscleLong thoracic NerveSerratus anteriorMusculocutaneous NerveCoracobrachialis muscleLateral anterior thoracic NervePectoralis major muscleThoracodorsal NerveLatissmus Dorsi
train
med_mcqa
null
False about acute aluminum phosphide poisoning
[ "Subendocardial infarct", "Produce phosphine gas", "Inhibit mitochondrial cytochrome oxidase", "Esophageal stricture" ]
D
Aluminum (zinc) phosphide or celphos poisoning liberates phosphine gas which inhibits mitochondrial cytochrome oxidase, respiratory chain enzymes and electron transport system. It is a systemic poison and kills most of patients with in 24 hours secondary to cardiovascular collapse due to direct myocardial toxic effect....
train
med_mcqa
null
Brown macular pigmentation in malar area in a pregnant female is due to ?
[ "Acne rosacea", "Cholasma", "Acanthosis nigricans", "Uicaric pigmentosa" ]
B
Ans. is `b' i.e., Cholasma Chloasma (Melasma) Melasma (Chlosma) is the most common cause for facial pigmentation in Indian patients. There is Brown macular pigmentation on the molar area of face, forehead and sometimes chin. It usually affects young and middle aged women. When melasma results from pregnancy it is refer...
train
med_mcqa
null
Estimation of the following hormones is useful while investigating a case of gynaecomastia except
[ "Testosterone", "Prolactin", "Estradiol", "Lutenizing hormone" ]
B
null
train
med_mcqa
null
Sulfonylureas act by:
[ "Decreasing glucagon secretion from pancreas", "Decreasing insulin secretion from pancreas", "Increasing gluconeogenesis", "Increasing insulin secretion from pancreas" ]
D
Ans. (D) Increasing insulin secretion from pancreas(Ref: KDT 8/e p294)Sulfonylureas stimulate the release of insulin by the beta cells of the islets of Langerhans by blocking K+ channels. Glucagon secretion is also reduced by sulfonylureas, but it is a minor action.
train
med_mcqa
null
At what period, Frequency is present in pregnancy:
[ "Before 16 weeks", "After 18 weeks", "After 20 weeks", "After 24 weeks" ]
A
Before 16 weeks
train
med_mcqa
null
Periodontal pockets which offer the least possibility for bone regeneration are classified as ________ pockets.
[ "suprabony", "one-wall infrabony", "two-wall infrabony", "three-wall infrabony" ]
B
null
train
med_mcqa
null
Large unilateral hypopigmented lesion on right trunk and arm in female. Which of the following best explain the etiology for it?
[ "Autoimmune hypothesis", "Neurogenic hypothesis", "Genetic factors", "Self destruct theory of Lerner" ]
B
Image shows large U/L hypopigmented lesion on right trunk and arm in young female: segmental vitiligo. Vitiligo Segmental Non segmental Unilateral along dermatome Localised Generalised Focal: few mucosal: mucosa -Vulgaris - MC, B/L symptoms - Acrofacial (including hand and face) - Universalis >90% Etio: Autoimmune cond...
train
med_mcqa
null
Screening of neonatal thyroid disease is done by -
[ "T4", "T3", "TSH", "TPO antibodies" ]
C
Ans. is 'c' i.e., TSH o Since the neonates are asymptomatic at birth all newborns are screened for neonatal hypothyroidism. TSH is estimated either in cord blood at the time of birth (preferred) or blood obtained from heel prick after 2 days of birth.
train
med_mcqa
null
Which one is not true regarding pseudocyst of pancreas -
[ "Epigastric mass", "Increase level of amylase", "Cystogastrostomy is the ideal T/t", "Percutaneus aspiration is the T/t" ]
D
Ans is 'd' ie Percutaneous aspiration is the t/t Percutaneous aspiration is preferred only in cases of infected cyst and abcesses, other wise internal drainage is the t/t of choice. Epigastric mass is the main symptom of pseudocyst. Increased level of amylase is usually elevated with pancreatic pseudocysts.
train
med_mcqa
null
Liddle syndrome is characterized by
[ "Hypokalemic metabolic alkalosis with hypotension", "Hypokalemic metabolic alkalosis with hypertension", "Hyperkalemic metabolic acidosis with hypotension", "Hyperkalemic metabolic acidosis with hypertension" ]
B
Liddle syndrome is an autosomal dominant disorder  with genetic defect(gain of function mutation) in collecting tubules sodium channel, resulting in increased tubular sodium reabsorption.
train
med_mcqa
null
A chronic alcoholic is presenting with clinical features of meningitis. Most likely organism which will grow on CSF culture -
[ "Streptococcus pneumoniae", "N. meningitidis", "Listeria monocytogenes", "E coli" ]
A
Ans. is 'a' i.e., Streptococcus pneumoniae o Streptococcus pneumoniae is the most common cause of meningitis in adults older than 20 years of age.o A number of predisposing conditions increase the risk of pneumococcal meningitis, the most common of which is pneumonia.o Additional risk factors include alcoholism, acute ...
train
med_mcqa
null
Use of dexemditomidine
[ "Prolong action of LA in hypeensive patients", "Sedative agent for intubated patients", "Increases bioavailability of regional anaesthetic drug", "Helps in reducing bispictral index of general anaesthetic drug with low potency" ]
B
DexmedetomidineIt is a centrally acting a-2 adrenergic agonistIt is approved by f.D.A for sho-term (<24 hours) continuous IV sedation of adults who are tracheally intubatedIts use as an anaesthetic agent is not recommended but it is useful in patients with brain injury and ongoing sedation needs.(Refer: Morgan and Mikh...
train
med_mcqa
null
The commonest site of peptic ulcer is
[ "1st pa of duodenum", "2nd pa of duodenum", "Distal 1/3 of stomach", "Pylorus of the stomach" ]
A
Conditions also. with peptic ulcer have already been described. Plummer Vinson Paterson Kelly syndrome consists of :- Iron deficiency anemia Dysphasia atrophic oral mucosa, glossitis brittle spoon-shaped fingernails. Typically pts are Woman over 40 yrs of age. Its a Pre-malignant condition* for both oral cavity & esoph...
train
med_mcqa
null
A 26-year-old male, Vikas presents to OPD complaining of hair loss and itching on scalp. Physical examination reveals moderate patchy hair loss from the cetral poion of scalp and the lesions have ring like configuration with central clearing. Which of the following drugs can be used to treat this patient's condition?
[ "Local glucocoicoids", "Progesterone", "Finasteride", "Terbinafine" ]
D
(Ref: Katzung 10/e p842) The diagnosis is Tinea capitis and terbinafine is used for the treatment. Male pattern baldness stas from anterior poion and scalp and are non-pruritic will family history. Tghe treatment of latter is finasteride.
train
med_mcqa
null
A patient with Cu. T but has conceived but does not want to continue conception ; Treatment of choice :
[ "Continue pregnancy", "Remove Cu - T and reinse", "Aboion but Cu - T in situ", "Menstrual regulation & sterilization" ]
D
Menstrual regulation & sterilization
train
med_mcqa
null
In atresia of cardiac end of stomach, X-ray chest is best done with:
[ "Conray 240", "Urograffin", "Barium sulphate", "Dianosil" ]
D
Ans. Dianosil
train
med_mcqa
null
A 8-year-old male child presented with complaints of pain and swelling in right distal femur for 5 months and also complained of on and off fever and significant weight loss along with loss of appetite. Lab studies revealed presence of anemia, leucocytosis and raised ESR & LDH. There was no history of any kind of traum...
[ "t(15:17)", "t(11:22)", "t(6:6)", "t(8:21)" ]
B
Ewings sarcoma 1st 2 decades of life Mimics osteomyelitis Second most common malignant primary bone tumors of childhood after osteosarcoma Typically arising from medullary cavity with invasion of the haversian system. Present as moth-eaten destructive permeative lucent lesions in the shaft of long bones with large soft...
train
med_mcqa
null
Loss of tooth Length of Premolar in case of orthodontic treatment?
[ "1.0 mm", "1.5 mm", "2.0 mm", "2.5 mm" ]
B
null
train
med_mcqa
null
Thyroid storm is seen in -
[ "Thyroid surgery", "Neonatal thyrotoxicosis", "Peri-operative infection", "All of the above" ]
D
Ans. is 'd' i.e., All of the above o Thyroid storm is a rare, life-threatening condition characterized by severe clinical manifestations of thyrotoxicosis.Risk factorso Although thyroid storm can develop in patients with long-standing untreated hyperthyroidism (Graves' disease,, toxic multinodular goiter solitary? toxi...
train
med_mcqa
null
A 42-year-old female patient has a malignancy involving the vestibule of her vagina. Which are the first lymph nodes to filter the lymph drainage from this area and therefore the most likely to become involved in tumor spread?
[ "Superficial inguinal", "Internal iliac", "Lumbar/lateral aortic", "Presacral lymph" ]
A
The superficial inguinal nodes drain superficial perineal structures, including the superolateral uterine body near attachment of the round ligament, skin of the perineum (including the vulva), and the introitus of the vagina inferior to the hymen. The internal iliac nodes drain the middle and upper vagina, cervix, and...
train
med_mcqa
null
Which of the following does not affect secretion of renin?
[ "Propranolol", "Indomethacin", "Enalkiren", "None of the above" ]
C
It is now possible to inhibit the secretion or the effects of renin in a variety of ways. Inhibitors of prostaglandin synthesis such as indomethacin and -adrenergic blocking drugs such as propranolol reduce renin secretion. The peptide pepstatin and newly developed renin inhibitors such as enalkiren prevent renin from ...
train
med_mcqa
null
Severity of disease is assessed by:
[ "Secondary attack rate", "Case fatality rate", "Prevalence rate", "Incidence rate" ]
B
Ans. is 'b' i.e. Case fatality rate Case fatality rate represents the killing power of the disease. It is closely related to virulence of the disease.
train
med_mcqa
null
Hallmark cells are seen in
[ "Diffuse large B cell lymphoma", "Hodgkin lymphoma", "Anaplastic large cell lymphoma", "Hairy cell leukemia" ]
C
Anaplastic large cell lymphoma is characterized by the presence of large bizarre cells, called Hallmark cells, with the embryo or horseshoe-shaped nuclei.
train
med_mcqa
null
Multiple cutaneous sebaceous adenoma are seen in
[ "Gardener's syndrome", "Turcott's syndrome", "Muir Torre syndrome", "Cowden Syndrome" ]
C
Ref: Hall manual of skin
train
med_mcqa
null
A six year old child presented with a valgus deformity at his right elbow since 3 years that is gradually progressive. He has a history of cast applied for 6 weeks after falling on outstretched hand 3 years back. The probable fracture was
[ "Malunited lateral Condylar fracture of Humerus", "Malunited Supracondylar Fracture of Humerus", "Posterior dislocation of elbow", "Fracture medial condyle of humerus" ]
A
Fractures commonly showing cubitus valgus deformity due to malunionFracture lateral condyle humerusMonteggia Fracture dislocation(Refer: Mohindra's Fundamentals of Ohopedics, 2nd edition, pg no. 16)
train
med_mcqa
null
LH is secreted by
[ "Ovary", "Pituitary", "Corpus luteum", "Hypothalamus" ]
B
Luteinizing hormone (LH, also known as lutropin and sometimes lutrophin is a hormone produced by gonadotropic cells in the anterior pituitary gland. In females, an acute rise of LH ("LH surge") triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell-stimulating...
train
med_mcqa
null
Commonest site of Hypeensive bleed is?
[ "Pons", "Putamen", "Frontal lobe", "Thalamus" ]
B
Putamen REF: Harrison's Internal Medicine 17th edition Chapter 364. Cerebrovascular Diseases Table 364-5 "Hypeensive intraparenchymal hemorrhage (Hypeensive hemorrhage or Hypeensive intracerebral hemorrhage) usually results from spontaneous rupture of a small penetrating aery deep in the brain. The most common sites ar...
train
med_mcqa
null
Rheumatoid factors are immunoglobulins directed against:
[ "The Fc poion of immunoglobulin G (IgG)", "The Fc poion of immunoglobulin A (IgA)", "The Fc poion of immunoglobulin M (IgM)", "The Fc poion of immunoglobulin D (IgD)" ]
A
The Fc poion of immunoglobulin G (IgG)
train
med_mcqa
null
Fine needle aspiration cytology is not suitable for diagnosing
[ "Tubercular lymphadenitis", "Papillary carcinoma thyroid", "Plasmacytoma", "Aneurymal bone cyst" ]
D
Aneurysmal bone cyst, abbreted ABC, is an osteolytic bone neoplasm characterized by several sponge-like blood or serum filled, generally non-endothelialized spaces of various diameters. On a radiograph, well-defined, expansile, lytic lesion is observed. Expansion of coex gives the lesion a balloon-like appearance. Larg...
train
med_mcqa
null
All of the following features are true about cross sectional study except -
[ "All cases are seen at one point in time", "Follow up is not a necessary feature", "More useful for chronic disease", "Cause and effect relationship can be estabilished" ]
D
Ans. is 'd' i.e., Cause and effect relationship can be established o In descriptive epidemiology it is mandatory to have a clear picture of the amount of disease (disease load) in the population. o Morbidity data can be obtained by following two studies - i) Cross - sectional studies ---> Prevalence ii) Longitudinal st...
train
med_mcqa
null
Hematopoietic stem cell differ from progenitor stem cell in that they can –
[ "Form terminally differentiated cells", "Produce growth factors", "Have receptors for anchoring proteins", "Long term reconstitution of bone marrow" ]
D
There are two major types of stem cells 1) Embryonic stem cells (ES) These are pluripotent cells which can differentiate into all the tissues of the human body. 2) Adult stem cells Adult stem cells have a more restricted differentiation capacity and are usually lineage-specific, i.e. multipotent or unipotent. There ...
train
med_mcqa
null
Which one of the following bone tumors typically affects the epiphysis of a long bone -
[ "Osteosarcoma", "Ewing's sarcoma", "Chondroblastoma", "Chondromyxoid fibroma" ]
C
It occurs mostly in the epiphysis of long bones.
train
med_mcqa
null
Mifepristone used for medical abortion is:
[ "Anti estrogen", "Anti progesterone", "Anti folate", "Prostaglandin derivative" ]
B
null
train
med_mcqa
null
Ovulation coincides with :
[ "Estrogen surge", "Progesterone surge", "FSH surge", "LH surge" ]
D
LH surge
train
med_mcqa
null
Phospholipids include all except
[ "Plasmalogens", "Dipalmitoyl lecithin", "Ceramide", "Cardiolipin" ]
C
Classification of lipids Phospholipids, containing phosphoric acid. 1. Nitrogen-containing glycerophosphatides: i. Lecithin (phosphatidylcholine) ii. Cephalin (phosphatidylethanolamine) iii. Phosphatidylserine 2. Non-nitrogen glycerophosphatides i. Phosphatidylinositol ii. Phosphatidylglycerol iii. Diphosphatidyl glyce...
train
med_mcqa
null
Shoest acting non depolarising muscle relaxant
[ "Succinylcholine", "Rapacuronium", "Atracurium", "Pancuronium" ]
B
Refer Miller's anesthesia 5/e p 892 Among the given options Rapacuronium IA the shoest acting drug Rapacuronium has been withdrawn from the market because it produces intense bronchospasm in a significant number of patients Mivacurium is shoest acting NDMR
train
med_mcqa
null
A 45-year old female had sought medical attention for her recent increase in weight and proximal limb weakness. She was diagnosed with rheumatoid ahritis. 1 week ago has been staed on prednisolone tablets. Physical examamination revealed truncal obesity; BP - 145/90 mm Hg and PR- -90/ mill. High levies of coisol were f...
[ "CT scan of the chest", "MRI of the brain", "CT scan of the abdomen", "Plasma metanephrine level" ]
B
Most of the signs and symptoms of ACTH-secreting tumors come from having too much coisol (an adrenal steroid hormone). But quite a few diseases can cause the body makes too much coisol, which is called Cushing's syndrome. If you have symptoms suggesting this syndrome, you'll need tests to see if it's caused by a pituit...
train
med_mcqa
null
Which of the following is not an anti histaminic drug of the ethanolamine group?
[ "Clemastine", "Diphenhydramine", "Dimenhydrinate", "Chlorpheniramine" ]
D
Ans. is d i.e., Chlorpheniramine Ethanolamine derivative group of antihistaminics are: Carbinoxamine maleate Clemastinefumarate Diphenhydrmine HC1 Dimenhydrinate
train
med_mcqa
null
DNA fingerprinting can be done with all, except: UP 07; Delhi 08; NEET 13
[ "RBC", "WBC", "Saliva", "Spermatozoon" ]
A
Ans. RBC
train
med_mcqa
null
Adverse effects of INH are all EXCEPT
[ "Peripheral neuritis", "Hepatitis", "Hypothermia", "Acne" ]
C
(C) Hypothermia # Adverse effects INH is well tolerated by most patients.> Peripheral neuritis and a variety of neurological manifestations (paresthesias, numbness, mental disturbances, rarely convulsions) are the most important dose dependent toxic effects.> These are due to interference with utilization of pyridoxine...
train
med_mcqa
null
Multiple myeloma has been seen commonly after exposure to
[ "Radioactive isotopes", "Gold", "Asbestos", "Organic dyes" ]
A
null
train
med_mcqa
null
Ureteric colic characterized by all EXCEPT:
[ "Acute onset", "Stillness of the patients", "Responds to antispasmodics", "Radiates to the groin" ]
C
(Respond to antispasmodics) (1317-Baily &Love 24th) (1274-Baily & Love 25th)Ureteric colic -* The patient is usually in such agony that only parenteral opioids will give relief: (1025-CSDT 12th)* There is a pattern of severe exacerbation on a back ground of continuing pain* Radiates to the groin, penis, scrotum or labi...
train
med_mcqa
null
In Osteoporosis which of these is seen?
[ "Normal calcium, normal ALP", "Decreased calcium, increased ALP", "Decreased calcium, decreased ALP", "Normal calcium, decreased ALP" ]
A
Ans. a. Normal calcium, normal ALP (Ref: Harrison 19/2493, 18/3120; Apley 9/131-133)Serum calcium, phosphate and alkaline phosphatase are normal in osteoporosis.OsteoporosisOsteoporosis is the MC metabolic bone disease.Osteoporosis is a state of decreased mass per unit volume (low bone density) of a normally mineralize...
train
med_mcqa
null
In what % of patients with hydatidiform mole height of uterus is more than expected for the period of amenorrrhea?
[ "10%", "30%", "50%", "70%" ]
D
Ans. d (70%). (Ref. Dutta, Obstetrics, 5th ed., 206)HYDATIDIFORM MOLE/VESICULAR MOLE# Abnormal condition of ovum with partly degeneration & partly hyperplastic changes in young chorionic villi.# It is benign neoplasia of chorion with malignant potential.# Highest incidence in Philippines (Southeast Asia).# In India 1 i...
train
med_mcqa
null
Which of the following disorders is NOT aggravated by corticosteroid therapy ?
[ "Congenital adrenal hyperplasia", "Diabetes mellitus", "Hypertension", "Peptic ulcer" ]
A
null
train
med_mcqa
null
Steroids are used in the Rx of the following diseases EXCEPT:
[ "Chronic fungal infection", "Erythema multiforme", "Pemphigus vulgaris", "Contact dermatitis" ]
A
Ans. a (Chronic fungal infection). (Ref. Harrison's principles of internal medicine, 16th ed., 2147)#ACTH deficiency-ADEM-Acute renal failure#ARDS-Alcoholic liver disease-Allergic rhinitis/sinusitis#Aspergillosis-Asthma-Atopic dermatitis#Autoimmune hepatitis-Behcet's syndrome-Bell's palsy#Brain tumors-Bronchocentric gr...
train
med_mcqa
null
A 24-year-old woman has been unsuccessful becoming pregnant. She is admitted with abdominal pain; her blood pressure is 90/60 mm Hg, her pulse rate is 102 beats per minute (bpm), and her hematocrit (HCT) is 28%. Features of ectopic pregnancy include which of the following?
[ "Elevated blood pressure on assuming an erect position", "Pulsus paradoxus", "Tenderness below the right subcostal margin (Murphy's sign)", "Pain referred to the supraclavicular region" ]
D
Free bleeding in the peritoneal cavity results in pain referred to the right supraclavicular region due to diaphragmatic irritation. Patients who present with abdominal pain and (usually) a history of missed menstruation should undergo a pregnancy test after hospital admission.
train
med_mcqa
null
Richest source of cholesterol is:
[ "Egg", "Hydrogenated oil", "Butter", "Cheese" ]
A
Egg
train
med_mcqa
null
Which of the following vasculitis is ANCA negative
[ "Microscopic polyangitis", "Churg straus syndrome", "Granulomatosis with polyangitis", "Polyarteritis nodosa" ]
D
ANCAs are not seen in Polyarteritis nodosa.
train
med_mcqa
null
Causes of antepaum hemorrhage are all except
[ "Placenta pre", "Atonic uterus", "Abruptio placenta", "Circumvallate placenta" ]
B
Atonic uterus
train
med_mcqa
null
Anterior segment of the eyeball includes structures lying in front of the:
[ "Iris", "Crystalline lens", "Vitreous body", "Cornea" ]
C
Ans. Cornea
train
med_mcqa
null
Adrenoleukodystrophy is?
[ "AD", "AR", "X linked dominant", "X linked recessive" ]
D
Ans. is 'd' i.e., X Linked recessiveAdrenoleukodystrophv:Adrenoleukodystrophy is an X-linked recessive disease associated with mutations in a member of the ATP-binding cassette transpoer family of proteins (ABCD1), which is involved in the transpo of molecules into the peroxisome.In the typical form of the disease, you...
train
med_mcqa
null
Most common arterial involvement causing ischemia of intestine is:
[ "Superior mesenteric artery thrombosis", "Inferior mesenteric artery thrombosis", "Hepatic artery thrombosis", "Celiac artery thrombosis" ]
A
Ans: A (Superior mesenteric artery thrombosis) Ref: Schwartz Textbook of Surgery, 10th edition, pg: 860; Mastery of Vascular and Endovascular Surgery - Gerald B. Zelenock - 2006, pg: 294 and Essentials of General Surgery, Peter F. Lawrence, 2006, pg: 459Explanation:"The SMA is the most commonly involved vessel in acute...
train
med_mcqa
null
What is the surgery of choice for diffuse type of choledochal cyst
[ "Resection and repair", "Rouxeny hepaticojejunostomy", "Liver transplant", "Observation" ]
B
Diffuse dilatation of the CBD is treated with resection and roux en y hepaticojejunostomy
train
med_mcqa
null
Drug of choice for treating anaphylaxis is :
[ "Adrenaline", "Corticosteroid", "Antihistaminic", "Sodium cromoglycate" ]
A
null
train
med_mcqa
null
Most common manifestation of mumps in adult males -
[ "Aseptic meningitis", "Encephalitis", "Orchitis", "Sinusitis" ]
C
Ans. is 'c' i. e., Orchitis o Orchiyid is the most common manifestation of mumps among postpubertal males
train
med_mcqa
null
Which is not seen in massive resection of small bowel?
[ "Hypogastrinemia", "Vitamin B12 deficiency", "Malabsorption", "Oxalate stone" ]
A
Ans. (a) HypogastrinemiaRef: Sabiston 19th edition, page 1274-1276* Due to loss of small intestine feedback inhibition to gastrin is lost -- hence there will be hypergastrinemia* 70% resection can be tolerated in small intestine* Proximal bowel resection is tolerated much better than distal bowel* Presence of terminal ...
train
med_mcqa
null
Cervical bulge. True is
[ "Enamel rods at cervical region directed occlusally", "Results in constriction at cervical region", "Is characteristic of deciduous teeth", "All of the above" ]
C
null
train
med_mcqa
null
A 2 year old boy presents with fever for 3 days which responded to administration of paracetamol, Three days later he developed acute renal failure, marled acidosis and encephalopathy. His urine showed *nt of oxalate crystals. The blood anion gap and osmolal gap were increased. Which of the following is the most likely...
[ "Paracetamol poisoning", "Diethyl glycol poisoning", "Severe malaria", "Hanta virus infection" ]
B
The clinical effects of DEG can be divided into three intervals. The first phase typically involves gastrointestinal effects such as nausea, vomiting, abdominal pain and diarrhea. Patients may be inebriated and mild hypotension has been repoed. Patients may have an abnormal osmolal gap and develop an anion gap metaboli...
train
med_mcqa
null
A Normal anion gap metabolic acidosis occurs in patients with?
[ "Diabetic ketoacidosis", "Methyl alcohol poisoning", "Diarrhea", "Acute kidney injury" ]
C
Diarrhea and Renal tubular acidosis (A) are two impoant causes of normal anion gap metabolic acidosis.
train
med_mcqa
null
Punishment for adultery is
[ "2years", "5 years", "7 years", "10years" ]
B
Man who commits the offence of adultery shall be punished with imprisonment up to 5 years or with fine or both. Ref: FORENSIC MEDICINE AND TOXICOLOGY DR PC IGNATIUS THIRD EDITION PAGE 308
train
med_mcqa
null
A 23 year old profession footballer suffered a twisting injury to his right ankle. On examination, there is a lot of swelling around the medial malleolus but x-ray doesn't show any fracture. The structure injured could be
[ "Deltoid Ligament", "Anterior talofibular ligament", "Spring ligament", "Tendo Achilles" ]
A
(Refer: Manish Kumar Varshney's Essential Ohopedics Principles & Practice, 1st edition, pg no. 1265 - 1267)
train
med_mcqa
null
True about V.S.D. is, all except :
[ "Small hole closes spontaneously", "Defect is usually in membranous pa", "Endocarditis is commonest complication", "Pulmonary oligemia in chest X-ray" ]
D
Answer is D (Pulmonary oligemia in X ray chest) D. is characterized by pulmonary plethora and not pulmonary oligemia. Pulmonary vasculature is increased - Chest X-ray in VSD does not show pulmonary oligemia. A ventricular septal defect results in shunting of oxygenated blood from left ventricle to the right ventricle. ...
train
med_mcqa
null
TATA box is seen in
[ "Promoter region", "Palindromic region", "Enhancer region", "Silencer region" ]
A
TATA box (also called the Goldberg-Hogness box) is a DNA sequence (cis-regulatory element) found in the promoter region of genes in archaea and eukaryotes Ref-D.M.Vasudevan 7/e p558
train
med_mcqa
null
About diphtheria true is -
[ "Capsulated bacteria causes infection", "Ratio of carriers and clinical cases is one", "Gram positive and motile", "Lysogenic phase causes disease" ]
D
null
train
med_mcqa
null
A 47-year-old woman presents with increasing headaches and visual changes. On examination, her pupils are normal and reactive to light, the extraocular movements are normal, and there are visual field defects of the outer half in both eyes (bitemporal hemianopsia). Which of the following is the most likely diagnosis?
[ "pituitary adenoma", "falx meningioma", "craniopharyngioma", "aneurysm of the internal carotid artery" ]
A
Adenomas of the pituitary gland constitute approximately 7% of intracranial tumors, with the chromophobic type being the most common. With macroadenomas, some degree of pituitary insufficiency is common, and half the patients have headaches. With microadenomas, the other pituitary functions may be completely normal.
train
med_mcqa
null
True regarding anaemia of chronic ds. are A/E -
[ "Decreased TIBC", "Increased macrophage iron in marrow", "Decrease serum ferritin level", "Decreased serum iron levels" ]
C
null
train
med_mcqa
null
Excitatory Neurotransmitter in CNS-
[ "Acetyl choline", "Glycine", "GABA", "Glutamate" ]
D
Glutamate is the chief excitatory neurotransmitter in CNS.
train
med_mcqa
null
Chemical process involved in conversion of progesterone to glucocoicoids is
[ "Methylation", "Hydroxylation", "Carboxylation", "None" ]
B
The reactions are effected by hydroxylationThese specific hydroxylases are monooxygenases These enzymes are NADPH dependentRef: DM Vasudevan, 7th edition, page no: 665
train
med_mcqa
null
Most common cause of endophthalmitis in AIDS patients is:
[ "Rhizopus", "Aspergillus", "Cryptococcus", "Candida" ]
D
Candida is most common cause of endophthalmitis in AIDS patients. Ocular Manifestations in HIV Anterior Segment Molluscum Contaiosum Herpes Zoster Ophthalmicus Kaposi Sarcoma Ocular Surface Squamous Neoplasia Trichomegaly Dry Eyes Anterior Uveitis Ocular Manifestations In HIV Posterior Segment CMV Retinitis Acute Retin...
train
med_mcqa
null
A 60-year-old man has his left forearm amputated because he has invasive rhabdomyosarcoma. The pathologist notes calcification in the wall of the radial aery, which otherwise appears unremarkable. Which of the following is the appropriate diagnosis?
[ "Churg-Strauss disease", "Complicated atherosclerotic plaque", "Fibromuscular dysplasia", "Monckeberg medial sclerosis" ]
D
Monckeberg medial sclerosis is characterized by calcification of the media of large and medium-sized aeries of older persons who are not otherwise affected by atherosclerosis . On gross examination, the involved aeries are hard and dilated. These aerial changes are usually asymptomatic. None of the other choices displa...
train
med_mcqa
null
Bi-Hogg-Dube syndrome is associated with increased risk of malignancy in which of the following organs?
[ "Stomach", "Lung", "Kidney", "Ovaries" ]
C
Bi-Hogg-Dube syndrome: Autosomal Dominant Defect in BHD gene which codes for folliculin Triad:- S:Skin manifestations (fibrofolliculomas, trichodiscomas, and acrochordons) R:Renal Cancer P:Pulmonary cysts or blebs
train
med_mcqa
null
Which of the following is not a part of child pugh score
[ "Albumin levels", "Bleeding time", "Ascites", "Bilirubin" ]
B
null
train
med_mcqa
null
Lecithin-Sphingomyelin ratio is used for
[ "Lung maturity", "Age of infant", "Kidney maturity", "Brain maturity" ]
A
Lecithin- Spingomyelin ratio is used for lung maturity. The results of this test are given as a ratio of lecithin to sphingomyelin. The range of results are: A ratio of less than 1.5:1. This means that your baby&;s lungs are immature. If born now, your baby may have breathing problems. A ratio between 1.5:1 and 1.9:1. ...
train
med_mcqa
null
Mouth breathing with enlarged adenoids and tonsils may be best described as:
[ "Anatomic", "Obstructive", "Physiologic", "Habitual" ]
B
null
train
med_mcqa
null
The exact value within +-2 SD in Standard normal curve
[ "98.8", "97.6", "95.4", "94" ]
C
Ans. c (95.4) (Ref. Methods in Bio-statistics, by B. K. Mahajan 6th edition, p. 79; Park PSM 22nd/pg.792)NORMAL DISTRIBUTION# When large number of observations of any variable such as height, blood pressure and pulse rate are taken at random to make it a representative sample, a frequency distribution table is prepared...
train
med_mcqa
null
Primary bone graft in cleft palate patient?
[ "6 month - 1 year", "< 2 year", "2-4 year", "4-5 year" ]
B
null
train
med_mcqa
null
Satellite nodule on a corneal ulcer is seen in
[ "Fungal infection", "Bacterial infection", "Viral infection", "Mycoplasma infection" ]
A
A i.e. Fungal infection Feature Found in Satellite lesion Fungal keratitis (corneal ulcer) C e.g. Aspergillus, Candida Sympathetic opthalmitis Q Dalen fuch's nodule, B/L granulomatous uveitis Dendritic & Geographic ulcer Herpes simplex Q Snow ball opacity in vitreous Pars planitis (intermediate uveitis), sarcoid Q, amy...
train
med_mcqa
null
Kawasaki's disease has the following features except?
[ "Cervical lymphadenopathy", "Strawberry tongue", "Thrombocytopenia", "Perianal peeling of skin/ desquamation" ]
C
Kawasaki's disease Clinical scenario : - ECG Findings of MI in 4 year old child 4 yrs C/F- Fever + 4 out of 5 of the following: 1. Cervical lymphadenopathy 2. Strawberry tongue 3. Rash 4. Perianal & periungual peeling of skin/desquamation 5. Bulbar congestion
train
med_mcqa
null
The drug of choice in mycoplasma pneumonia in children is –
[ "Tetracycline", "Streptomycin", "Cotrimoxazole", "Erythromycin" ]
D
Treatment of pneumonia in children For mildly ill patient (not require hospitalization) Empirical treatment → Amoxicillin is the DOC. Atypical (mycoplasma) pneumonia → macrolides (Azithromycin, Erythromycin). For Hospitalized patients IV cefuroxime or cefotaxime or ceftriaxone. If clinical features suggest staph...
train
med_mcqa
null
True statement (s) about salivary gland tumours -a) Pleomorphic adenoma can arise in submandibular glandb) Wahim's tumour arises from submandibular glandc) Pleomorphic adenoma is most common tumour of sub mandibular glandd) Acinic cell Ca is most malignante) Frey's syndrome is due to injury of auriculotemporal nerve
[ "cde", "acd", "ace", "ade" ]
C
Pleomorphic tumor is the most common benign tumor of the salivary glands and can arise in any of the salivary gland. It is the most common tumor of the parotid, submandibular & sublingual glands (Most common tumor of minor salivary glands are Adenoid cystic Ca & mucoepidermoid ca.) Wahin's tumor arises only from the pa...
train
med_mcqa
null
In posterior compament syndrome which passive movement causes pain ?
[ "Dorsiflexion of foot", "Foot inversion", "Toe dorsiflexion", "Toe planter flexion" ]
A
POSTERIOR COMPAMENT SYNDROME : Rise in pressure within the compaments of limbs due to any reason may jeopardise blood supply to the muscles and nerves within the compament, resulting in what is known as compament syndrome. It can assessed by STRETCH TEST. Which is the earliest sign of impending compament syndrome. Isch...
train
med_mcqa
null
A one-week-old baby develops nuchal rigidity and fever. A lumbar puncture is performed and the cerebrospinal fluid demonstrates large numbers of neutrophils. Which of the following is the most likely causative agent?
[ "Coxsackievirus", "Escherichia coli", "Herpes virus", "Mycobacterium tuberculosis" ]
B
The nuchal rigidity (stiff neck) suggest meningitis. Numerous neutrophils in the cerebrospinal fluid suggests a bacterial pathogen. The best answer of those listed is Escherichia coli, which is normally a gut organism, but can infect neonates who acquire the organism during passage through the bih canal. Coxsackievirus...
train
med_mcqa
null
22 year old female comes to your OP complaining of frequent periods which comes every 18 days. What is this condition called?
[ "Polymenorrhea", "Menorrhagic", "Metrorrhagia", "Hyper menorrhea" ]
A
Polymenorrhea or frequent periods, describes regular periods that occur less than 21 days apa. Ovulatory polymenorrhea is a result of shoened proliferative phase seen in adolescence and attributed to hypersensitive ovaries. In older women the shoened cycles may be due to progressive ovarian failure leading to luteal de...
train
med_mcqa
null
Ferrous sulfate is hydrated salt containing______ % Iron.
[ "20", "25", "30", "35" ]
A
Ans. a (20%) (Ref. KDT, Pharmacology, 6th ed., 584)Oral Iron preparationsIron contentFerous sulfate Hydrated salt20%Dried salt32-35%Ferous gluconate12%Ferous fumarate, succinate33%Colloidal ferric hydroxide50%Iron-calcium complex5%Vital points about IRON THERAPY# Some iron preprations come with other compounds designed...
train
med_mcqa
null
Chronic hemodialysis in ESRD patient is done
[ "Once per week", "Twice per week", "Thrice per week", "Daily" ]
C
Ans. (c) Thrice per weekRef : Harrison 19th ed. /1823For the majority of patients with ESRD, between 9 and 12 h of dialysis are required each week, usually divided into three equal sessions.Current Targets of Hemodialysis* Urea reduction ratio (the fractional reduction in blood urea nitrogen per hemodialysis session) o...
train
med_mcqa
null
All of the following are seen in polycythemia rubra vera except :
[ "Increased Vit B12 binding capacity (>9000 micromols/dL)", "Decreased LAP Score", "Leucocytosis", "Increased platelets" ]
B
Answer is B (Decreased LAP Score): Leucocyte alkaline phosphatase is increased in polycythemia vera Characteristic features associated of polycythemia vera Elevated Red Cell Mass/ haematocrit (polycythemia)Q Normal aerial oxygen saturation (a low oxygen saturation would be a physiological stimulus) Plasma erythropoetin...
train
med_mcqa
null
All are seen in Transient Tachypnea of the new born Except
[ "Associated with Grunting& cyanosis", "Associated with Rhonchi crackles", "Presence of Interlobar effusion", "Early onset in neonatal period" ]
B
Transient Tachypnea of the New bornPathophysiologyClinical featuresSlow resorption of lung fluid.Pulmonary compliance |Tidal volume |Dead space |Disease of exclusion.Rapid & early onsetRecovery within 3 days.No/minimal cyanosis.Grunting +-X-ray featuresComplicationsProminent pulmonary vessel markings.Fluid in interloba...
train
med_mcqa
null
All of the following are true of Neurocysticercosis EXCEPT
[ "Albendazole is the drug of choice", "More common in vegetarians", "Produces intracerebral calcification", "Man is the definitive host" ]
B
(B) More common in vegetarians # NEUROCYSTICERCOSIS (NCC) is caused by the CNS infection with the pork tapeworm Taenia solium, which is endenic in most low-income countries where pigs are raised.> Perpetuation of this parasitic disease is related to poor sanitation and hygiene.> Clinical presentation: There is a variab...
train
med_mcqa
null
Blood transfusion is indicated in following condition with sickle cell anemia
[ "Frequent sickling episodes", "Twin pregnancy", "Poor obstetrical outcome", "All of the above" ]
D
Indications of Blood transfusion in Sickle Cell Anemia Frequent sickling episodes Twin pregnancy Poor obstetrical outcome Severe anemia Blood transfusion replaces the abnormal cells with normal red cells The objective of transfusion is to keep the hematocrit value above 25% and concentration of Hb-S under 50% Prophylac...
train
med_mcqa
null
A young lady presented with bilateral nodular lesions on shins. She was also found to have bilateral hilar lymphadenopathy on chest X-ray. Mantoux test reveals indurations of 5 mms. A skin biopsy would reveal -
[ "Non caseating Granuloma", "Vasculitis", "Caseating Granuloma", "Malignant cells" ]
A
Skin lesions in this patient is Erythema nodosum. Erythema nodosum, bilateral hilar lymphadenopathy negative Mantoux test is strongly suggestive of sarcoidosis. Skin biopsy (or biopsy from hilar nodes, conjunctiva, lip, or spleen, intraabdominal nodes) would reveal non-caseating granulomas. Signs and symptoms of sarc...
train
med_mcqa
null
Which of the following micronutients have a role in regulation of binding of proteins to DNA?
[ "Zinc", "Copper", "Selenium", "Nickel" ]
A
Protein-DNA interactions are regulated by several motifs which includes Helix turn-Helix motif, Zinc finger motif and Leucine Zipper motif.
train
med_mcqa
null
Broad Granular casts are seen in
[ "Chronic renal failure", "Glomerular injury", "Thrombotic Microangiopathy", "Pyelonephritis" ]
A
Broad granular casts - Chronic renal failure. RBC casts - Glomerular injury.
train
med_mcqa
null
The poor indicator of response during treatment of malnutrition includes
[ "Failure to gain appetite by day 10", "Presence of edema on day 10", "Failure to gain at least 5 g/kg/day by day 4", "Failure to gain at least 2 g/kg/day by day 10" ]
B
Primary failure to respond may be characterized by:1. Failure to regain appetite by day 42. Failure to sta losing edema by day 43. Failure of the disappearance of edema by day 104. Failure to gain weight at least by 5g/kg/day by day 10 of therapyRef: Nelson Paediatrics; 20th edition
train
med_mcqa
null
Not a feature of Hartnup's disease:
[ "Pellagroid skin lesion", "Cerebellar ataxia", "Mental retardation", "Psychological disturbances" ]
C
c. Mental retardation(Ref: Nelson's 20/e p 636-642, Ghai 8/e p 653-655)Clinical features of Hartnup disease:Most children with Hartnup defect remain asymptomaticMajor clinical manifestation in symptomatic patient is cutaneous photosensitivity: pellagra-like rash on sun exposureSome patients may have intermittent ataxia...
train
med_mcqa
null
If neonatal death 450, stillb ibh 212, total live bih 12450, what is the NMR?
[ "17", "36", "64", "92" ]
B
Neonatal moality rate= number of deaths of children under 28 days of age in a year/total live bihs*1000 =450/12450*1000 =36
train
med_mcqa
null
All the following can be used to predict severe acute pancreatitis except NOT RELATED MEDICINE
[ "Glasgow score > 3", "CT severity score > 7", "APACHE-II score >8", "Serum lipase >5 times the normal" ]
D
.
train
med_mcqa
null
Dietery factors associated with colon carcinoma -a) High fiberb) Low fiberc) Smoked fishd) High fat intakee) Japanese are common to develop Ca colon
[ "abc", "ade", "ace", "bde" ]
D
A high incidence of colorectal cancer is seen in economically prosperous, upper socioeconomic class. This observation led to attention on environmental factors, particularly diet in the etiology of colon cancer. Dietary factors associated with colon cancers are: Animal fat diet high in animal fats such as found in r...
train
med_mcqa
null