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Differences between IMNCI and IMCI include the following-
[ "Identification and classification of common illnesses like malaria, diarrhoea, malnutrition", "Incorporated guidelines on immunization", "Training time devoted to sick young infant is more than for a child", "IM NCI includes 0-7 days age programme" ]
D
Ans. is `d i.e., IMNCI includes 0-7 days age programme
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Blood-testis barrier is formed by -
[ "Sertoli cells", "Leydig cells", "Epididymis", "Vas deferens" ]
A
Ans. is 'a' i.e., Sertoli cells o Blood brain barrier - Tight junction between endothelial cells and some reinforcement by foot process of astrocytes.o Blood CSF barrier -Tight juction between endothelial cells plus tight junction between choroidal epithelial cells.o Blood testis barrier - Tight junction betw-een endot...
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The oxygen--hemoglobin dissociation curve is sigmoid because
[ "Binding of one oxygen molecule increases the affinity of binding other 02 molecule", "Binding of one oxygen molecule decrease the affinity of binding other 02 molecules", "Oxygen affinity of Hemoglobin decreases when the pH of blood falls", "Binding of oxygen to Hemoglobin reduces the affinity of Hb for CO2"...
A
Binding of one oxygen molecule increases the affinity of binding other 02 molecules
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Rotator cuff tear results from tear of one or more of the rotator cuff muscles and their associated tendons. Which is the most commonly injured rotator cuff muscle?
[ "Supraspinatus", "Infraspinatus", "Teres minor", "Subscapularis" ]
A
Supraspinatus is the most frequently injured muscle or tendon. Most of the injury result from overuse. Supraspinatus muscle: Its primary action is humeral abduction. The suprascapular nerve (C5-C6) and the suprascapular aery provide its innervation and blood supply.Infraspinatus muscle: Its primary action is lateral ro...
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A young lady was admitted after taking overdose of diazepam after broken affair. She has history of slitting her wrist previously. Most likely diagnosis is
[ "Narcisstic Personality Disorder", "Dependent P.D.", "Borderline P.D.", "Histirionic P.D." ]
C
C i.e. Border line Personality disorderIn Personality disorders - that onset can be traced back atleast to adolescence or early adulthood; the behaviour detes markedly from the expectations of individual culture, is inflexible & pervasiveQ across a broad range of personal & social situations.
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Position for orotracheal intubation?
[ "Extension of neck and atlantoccipital joint", "Extension of only neck", "Flexion of neck only", "Flexion of neck and extension of atlantoccipital joint" ]
D
Ans. d (Flexion of neck and extension of atlantoccipital joint) (Ref. Head and Neck Surgery - Otolaryngology 3rd/Ch. 58)OROTRACHEAL INTUBATION# Orotracheal intubation is undertaken ideally with the patient in the sniffing position, the patient's neck flexed slightly on the chest, and the head extended slightly on the n...
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Dominant parietal lobe injury leads to all of the following except: March 2005
[ "Agnosia", "Dysphasia", "Dyscalculia", "Urinary incontinence" ]
D
Ans. D: Urinary incontinence Dysfunction of the posterior superior frontal gyri and anterior pas of the cingulate gyrus can lead to incontinence of urine and stool. Patients frequently have no warning of the need to urinate or defecate, and are surprised and embarrassed when they find they have soiled themselves.
train
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After a major oral surgery, acute catabolic phase lasts for?
[ "1-2 days", "2-5 days", "4-7 days", "5-10 days" ]
B
null
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Paogram is used for: March 2011
[ "Determining pattern of fetal hea rate", "Determining position of cervix", "Assessing integrity of utero-placental unit", "Recording progress of labour" ]
D
Ans. D: Recording progress of labour Paograph is a composite graphical record of key data (maternal and fetal) during labour, entered against time on a single sheet of paper Remember: Assessment of labour is best done by paogram Graph showing relationship between cervical dilatation and labour is cervicograph Bishop's ...
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Agar is added to Broth medium:
[ "To make the medium liquid", "To make the medium solid", "To provide extra nutrition to grow", "None" ]
B
Ans. B. To make the medium solida. Broth media can be made solid by adding agar, a gel like polysaccharide extracted from red algae,b. Broth with about 1.5% agar added will be liquid when heated, but solid at room temperature, making it easy to pour into a vessel, such as a Petri dish or test tube when hot.c. The solut...
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Select inappropriate statement regarding Cholera
[ "Incubation period 1-2 days", "Rice - watery diarrhoea", "Azithromycin is treatment of choice in adults", "It is a notifiable disease locally, nationally and internationally" ]
C
Cholera: - Caused by Vibrio cholera - ELTOR - MC subtype in India now. - Route of transmission - FECO-ORAL ROUTE - I.P - 1-2 days - Clinical feature: Rice-watery diarrhea - It is a notifiable disease locally, nationally and internationally. Groups Antibiotic of choice for cholera Adults Doxycycline Children Azithromyci...
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Branded chain ketoacid decarboxylation is defective in
[ "Maple syrup urine disease", "Hanup disease", "Alkaptonuria", "GM1 gangliosidosis" ]
A
Maple Syrup Urine Disease (MSUD) i. It is also called branched-chain ketonuria. The incidence is 1 per 1 lakh bihs. The name originates from the characteristic smell of urine (similar to burnt sugar or maple sugar) due to excretion of branched-chain keto acids. ii. The basic biochemical defect is deficient decarboxylat...
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Derivative of third pharyngeal pouch is:
[ "Thymus", "Inferior parathyroid gland", "Both of the above", "None of the above" ]
C
In the fifth week, epithelium of the dorsal region of the third pouch differentiates into the inferior parathyroid gland, while the ventral region forms the thymus. Ref: Langman's embryology 11th edition Chapter 16.
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Myosin and actin filaments are kept in place by
[ "Tropomyosin", "Troponin", "Actinin", "Titin" ]
D
Titin keeps actin and myosin in place It povides elasticity It is present in skeletal and cardic muscles Ref:Guyton and Hall textbook of medical physiology 12th edition ,pag number:85,86,87
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A post operative cardiac surgery patient developed sudden hypotension, raised Central venous pressure, pulsus paradoxus at the 4th post operative hour .The most probable diagnosis is
[ "Excessive mediastinal bleeding", "Ventricular dysfunction", "Congestive cardiac failure", "Cardiac tamponade" ]
D
Ref Harrison 19 th ed pg 1573-1574 Features of rising pressure , falling aerial pressure and pulsus paradoxus following surgery on the hea leads us to the diagnosis of cardiac tamponade.
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Forced alkaline diuresis cannot be done in which poisoning
[ "Barbiturates", "Salicylates", "Alcohol", "Methotrexate" ]
C
Forced alkaline diuresis It is a method to achieve a urinary pH 7.5 to 9 and promote the excretion of the drug through urine, Eg: salicylates, barbiturates, chlorpropamide, methotrexate. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 403
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The drug of choice in pheochromocytoma is:
[ "Phenoxybenzamine", "Propranolol", "Prazosin", "Phentolamine" ]
A
Ans: a (Phenoxybenzamine)Ref: Thripathi 5 ed., Pg. 122Phenoxybenzamine is the drug of choice for controlling hypertension in pheochromocytomaManagement of PheochromocytomaComplete tumour removal is the ultimate therapeutic goal.Phenoxybenzamine should be initiated at relatively low doses (e.g., 5-10 mg orally three tim...
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In an infant, bone marrow biopsy is done from
[ "Tibia", "Sternum", "Posterior superior iliac spine", "iliac crest" ]
A
. The tibia is the site for bone marrow biopsy in the newborn infant and in children under 2 years of age. Ref Robbins 9/e pg 261-262
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The posterior urethra is best visualized by –
[ "Static cystogram", "Retrograde urethrogram", "Voiding cystogram", "CT cystogram" ]
C
Micturating / Voiding cystourethrography is the best method to visualize posterior urethra, posterior urethral valve and vesico ureteric reflux.
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Increase in D- dimer levels are noticed in immediate post-op period. Most appropriate cause is
[ "Deep vein thrombosis", "Pulmonary embolism", "Disseminated intra vascular coagulation", "Normal" ]
A
Deep vein thrombosis Deep vein thrombosis (DVT) is a well-known and, when complicated by pulmonary embolus, potentially fatal complication of surgery. All hospitals must have a pro cess for screening all surgical patients to identify those at risk and for implementing prophylactic measures. There is inter- national agr...
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Medical sociology views illness as ?
[ "Purely medical problem", "Medical and environmental problem", "Medical and psychosocial problem", "Psychosocial problem" ]
C
Ans. is 'c' i.e., Medical and psychosocial problem Medical sociology is a specialization within the field of sociology.Its main interest is in the study of health, health behaviour and medical institutions.As a specialized field, it was first proposed by Charles McIntire in 1894.It is defined as "professional endeavour...
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Fluid containing which of the following substance is used in peritoneal dialysis
[ "NaCl", "Urea", "Heparin", "Dextrose" ]
D
In peritoneal dialysis, 1.5-3 L of a dextrose-containing solution is infused into the peritoneal cavity and allowed to dwell for a set period of time, usually 2-4 h. Peritoneal dialysis solutions are available in volumes typically ranging from 1.5 to 3 L. The major difference between the dialysate used for peritoneal ...
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True statement about rheumatization of MVa) Fusion & shortening of chordae tendineae in MSb) Calcification of MVc) Aortic dilationd) Annular involvement
[ "acd", "bcd", "abc", "abd" ]
D
null
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A patient with necrotizing pancreatitis undergoes CT guided aspiration, which results in growth of E-coli on culture. The most appropriate treatment is:
[ "Culture appropriate antibiotic therapy", "ERCP with sphincterotomy", "CT guided placement of drain(s)", "Exploratory laparotomy" ]
D
Exploratory laparotomy The presence of secondary pancreatic infection suspected in patients whose systemic inflammatory response (fever, WBC count or organ dysfunction) fails to resolve, CT-guided aspiration of fluid from pancreatic bed for performance of Gram's stain & culture analysis is of critical impoance. A posit...
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If a drug is active against the pre–erythrocytic stage of the malarial parasite it will be useful as a :
[ "Suppressive prophylactic", "Causal prophylactic", "Clinical curative", "Radical curative" ]
B
null
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Supination and pronation occurs at which of the following joint: September 2006
[ "Wrist joint", "Elbow joint", "Radio-ulnar joint", "Carpometacarpal joint" ]
C
Ans. C: Radio-ulnar Joint Supination and pronation occurs at the radio-ulnar joint. The radius revolves on the ulna about an axis which passes through the centre of the head of the radius above and the styloid process of the ulna below, which line if prolonged would pass through the ring finger. In pronation, the hand ...
train
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Which enzyme prevents aging?
[ "DNA ligase", "DNA polymerase a", "Telomerase", "RNA polymerase II" ]
C
Ans. is 'c' i.e., Telomerase* A person can be young only until the person can replenish the losses periodically, for which the cells should be pushed into cell cycle regularly.* Telomeres are ends of chromosomes which help in maintaining the stability of our chromosomes. When we are born we are born with a particular t...
train
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Ringed sideroblasts are seen in:
[ "AML", "MDS", "Anaemia of chronic disease", "ALL" ]
B
- MDS: These are commonly associated with Ringed sideroblasts. Other conditions associated with Ringed sideroblasts are : Congenital sideroblastic anemia Lead poisoning Anti-tubercular drugs like isoniazid Pyridoxine deficiency Anemia due to alcoholism. - Their presence can be confirmed with Perl's stain
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Which inhalational agent is used in patients with raised intra cranial tension?
[ "Enflurane", "Isoflurane", "Desflurane", "Sevoflurane" ]
B
Isoflurane causes least vasodialation and hence helps to moderate the cerebral blood flow. It reduces the ICT and hence is useful in neurosurgery. It is more potent than halothane and has rapid onset of action and induction. Reference 1. Quick Review of Pharmacology, By Dr J G Buch, Page 204
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Commonest indication for..... liver transplantation in infant is -
[ "Alcoholic cirrhosis", "Biliary cirrhosis", "Primary hemochromatosis", "Biliary atresia" ]
D
Ans is d i.e.; Biliary atresia
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All of the following drugs cause discolouration of urine EXCEPT:
[ "Nitrofurantoin", "Digoxin", "Azo dyes", "Rifampicin" ]
B
ESSENTIALS of medical PHARMACOLOGY SEVENTH EDITION -KD TRIPATHI Page:515,516
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Egocentric and magical thinking, excessive emotionality and attention seeking pattern is associated with which type of personality?
[ "Schizoid", "Schizotypal", "Avoidant", "Narcissistic" ]
D
Narcissistic PD. This question best describes Histrionic PD, which is not given in the option. Hence, Narcissistic PD would be the best option as question describes egocentricity.It is a type of Cluster B PD in which person gives excessive self impoance and believes that he is special and talented and has fantasies of ...
train
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Not a branch of posterior cord of Brachial plexus
[ "Axillary nerve", "Thoracodorsal nerve", "Radial nerve", "Ulnar nerve" ]
D
Long thoracic nerve arises from the nerve root of C5-C7 and it supplies serratus anterior muscle. The axillary nerve supplies the deltoid and teres minor muscles. The thoracodorsal nerve supplies the latissimus dorsi muscle. The radial nerve supplies 3 heads of triceps brachii and 12 muscles on the back of the forearm....
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Most common site of Basal cell carcinoma on face is
[ "Forehead", "Ears", "Nose", "Cheeks" ]
C
Face is the most common site for BCC And nose is the most common site on face.
train
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Taeniae coli is found is
[ "Duodenum", "Jejunum", "Ileum", "Ascending colon" ]
D
(Ascending colon) (254-BDC-2 4th)Differences between small intestine and the large intestineFeaturesSmall IntestineLarge Intestine1. Appendices epiploicaeAbsentPresent*2. Taeniae coliAbsentPresent*3. SacculationsAbsentPresent4. DistensibilityLessMore5. FixityGreater part is freely mobileGreater part is fixed6. VilliPre...
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True about MRI/CT appearance of lateral meningocele:
[ "Solid dural masses", "Usually outside the spinal canal", "Widened neural foramen", "Generally there is no spinal cord compression & deformity" ]
C
C i.e. Widened neural foramen - Lateral meningocele is non solid, CSF containing leptomeningeal outpouching through widened neural foramen usually into paraspinal, intrathoracic spaceQ. And it is generally associated with spinal deformities like, posterior (dorsal) scalloping, erosion of pedicles, thinning of neural ar...
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Highest level of integration in health service is?
[ "PHC", "Sub centre", "CHC", "Distric hospital" ]
A
The Bhore committee in 1946 gave the concept of primary health center as a basic health unit to provide as close to the people as possible an intergrated curative and preventive health care to the rural population with emphasis on preventive and promotive aspects of health care (refer pgno:904 park 23rd edition)
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Commonest site of meningomyelocele is :
[ "Lumbosacral", "Cranial", "Thoracic", "None of the above" ]
A
Myelomeningocele can occur at any spinal level but usually is seen between levels T12 and S2. Because neural tissue fails to form properly, the child is paraplegic and insensate below the level of the dysraphism. The clinical determination of neurologic level is most easily accomplished by describing the last muscles c...
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Most common side effect of calcium channel blockers is
[ "Nausea", "Constipation", "Postural hypotension", "Headache" ]
D
Calcium channel blockers: Most common side effect is headache CCB cause flushing, headache, angioedema, reflex tachycardia. Verapamil, diltiazem- both vasodilation and decrease in hea rate Nifedipine, clevidipine - only vasodilation but increase in hea rate. Avoid in angina.
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Bacteria causing vomiting and diarrhea within 6 hours of food intake is: March 2005
[ "Clostridium perfringens", "Salmonella spp", "Vibrio cholerae", "Staphylococci aureus" ]
D
Ans. D: Staphylococci aureus Incubation period of: a. 1-6 hours: Staphylococci aureus b. 8-16 hours: Clostridium perfringens c. More than 16 hours: Salmonella spp.,Vibrio cholerae Staphylococcal food poisoning: Typical contaminated foods include custard, cream-filled pastry, milk, processed meats, and fish. Symptoms us...
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Castellani's paint contains all of the following except
[ "Basic fuchsin", "Phenol", "Benzene hexachloride", "Boric acid" ]
C
Castellani's paint is used to disinfect skin and to treat 'fungus infections of the skin. Its components are phenol, resorcinol, basic fuchsin, boric acid, and acetone.
train
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The characteristic alarm clock headache is a feature of
[ "Auriculotemporal Neuralgia", "Trigeminal Neuralgia", "SphenopaLatine Neuralgia", "Glossopharyngeal Neuralgia" ]
C
null
train
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Which of the following can be given in hepatic as well as in renal failure
[ "Atracurium", "Vecuronium", "Pancuronium", "Mivacurium" ]
A
Atracurium and Cis-atracurium are the muscle relaxants of choice in both liver and renal failure. Atracurium is inactivated by Hoffman's elimination and alkaline ester hydrolysis. Cis-atracurium is eliminated by Hoffman's elimination. Hence atracurium and cis-Atracurium duration of action is not altered in patients wit...
train
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Condition associated with obesity are all except -
[ "Pheochromocytoma", "Hypothyroidism", "Insulinoma", "Cushing's syndrome" ]
A
null
train
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Intestinal anastamosis strength provided by:
[ "Mucosa", "Submucosa", "Serosa", "Muscularis mucosa" ]
B
Ref: American College of Surgeons text hook of Surgery, 6th edition. Chapter on Intestinal Anastamosis.Explanation:Strongest component of bowel wall is submucosa. due to the presence of collagen.The process of intestinal anastomotic healing mimics that of wound healing elsewhere in the bodyIt can be arbitrarily divided...
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Which among the following is FALSE regarding Thallium poisoning ?
[ "Can be used as Ideal homicidal poison", "Chronic poisoning of Thallium causes alopecia, skin rashes, painful peripheral neuropathy", "Cannot be detected even in ashes of burnt body", "Mees' lines can be seen on nails" ]
C
Thallium poisoning Odourless, tasteless and water soluble Hair loss Mee's line Chronic poisoning of Thallium causes alopecia, skin rashes, painful peripheral neuropathy Can be detected even in ashes of burnt body Death due to respiratory failure. Mee's lines are seen in arsenic poisoning. Not specific only for arsenic....
train
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Microlaryngoscopy was started by
[ "Bruce Benjamin", "Kleinsasser", "Chevlier Jackson", "None of the above" ]
B
Ans. b (Kleinsasser). (Textbook of ENT by Maqbool, 7th ed., 407)# Microlaryngoscopy = Kleinsasser# Tracheostomy tube = Chevlier Jackson# Bronchoscope = Negus, Jackson
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A healthy 30-year-old woman comes to the physician for a routine health maintenance examination. No abnormalities are found on physical examination. A screening Pap smear shows cells consistent with a low-grade squamous intraepithelial lesion (LSIL). Subsequent cervical biopsy specimens confirm the presence of cervical...
[ "Diethylstilbestrol (DES) exposure", "Multiple sexual partners", "Oral contraceptive use", "Prior treatment for a malignancy" ]
B
Cervical intraepithelial neoplasia (CIN) I represent minimal (mild) dysplasia (low-grade squamous intraepithelial lesion, or LSIL) and is a potentially reversible process. Dysplasia is preneoplastic and may progress to carcinomas if not treated. Risk factors for cervical dysplasia and carcinoma include early age at fir...
train
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All are transmitted by blood except aEUR'
[ "Parvovirus B-19", "Hepatitis G", "Epstein Bar virus", "Cytomegalovirus" ]
C
Epstein Barr Virus ??? Viruses associated with blood transfusion: Hepatitis C virus: Hepatitis G virus: Hepatitis B virus HIV type I HTLV Type Cytomegalovirus Parvovirus 13-19 HGV A recently discovered and identified non A-E hepatitis virus has been designated the name Hepatitis G virus (HGV) which is a member afflaviv...
train
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Poal vein is formed by union of:
[ "SMV & SV", "SMV & IMV", "IMV & SV", "IMV + Hepatic vein" ]
A
SMV & SV
train
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Menke's Kinky hair syndrome is due to defect in
[ "Ca transporter", "Cu transporter", "Zn transporter", "Se transporter" ]
B
Menke's kinky hair syndrome is due to mutation in ATP7A gene, leading defective copper transporter.
train
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Radioiodine is preferred for the treatment of
[ "Young patient", "Pregnancy", "Recent onset of toxic goiter", "Diffuse Toxic goiter in > 45 years old" ]
D
Ans. (d) Diffuse toxic goiter in > 45 years old.Ref: Schwartz 10th edition, Page 1533Contraindications for RAI ablation in Graves' disease* Pregnancy* Lactation* Young (Children and adolescents)* Nodules in thyroid gland* Ophthalmopathy (Progression of Graves ophthalmopathy happens)
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Soft exudates are found in:
[ "DM", "HTN", "Toxemia", "All" ]
D
Ans. All
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Which of the following is the most common form of primary immunodeficiency?
[ "AIDS", "Wiskott-Aldrich syndrome", "Common variable immunodeficiency", "Selective IgA immunodeficicy" ]
D
Selective IgA deficiency (less than 15mcg/ml) is the most common type of primary immunodeficiency. Individuals develop recurrent acute and chronic respiratory infections that may lead to bronchiectasis. These patients are at an increased risk of drug allergies, atopic disorders and autoimmune diseases. Ref: Harrison's ...
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Apex of lung is best assessed by –
[ "AP view", "PA view", "Lordotic view", "Oblique view" ]
C
Apical lordotic view is used for lung apices, and for recognizing the collapse of lingula or middle lobe.
train
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A pregnant 35-year-old patient is at highest risk for the concurrent development of which of the following malignancies?
[ "Cervix", "Ovary", "Breast", "Vagina" ]
A
Ans. is a, i.e. CervixRef: Williams obs 25/e, 1190
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A 49-year-old male, chronic alcoholic presented to ER with complaints of fever, progressive lethargy and confusion for 2-3 days. On examination, Hypotension Tachycardia Distended diffusely tender abdomen Positive fluid wave The doctor advised USG of the abdomen which revealed irregular outline of liver with coarsened e...
[ "Ferment glucose with acid production", "Reduce nitrates to nitrites", "Oxidase negative", "Phenylalanine deaminase positive" ]
D
This is a case of spontaneous bacterial peritonitis in a patient with chronic liver disease. It is spontaneous because there is no apparent source of contamination. Neutrophil count of > 250/ microL is diagnostic. Most commonly caused by enteric gram-negative bacilli. Enterobacteriaceae Gram negative Oxidase negative F...
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Pulmonary hypeension may occur in all of the following conditions, EXCEPT:
[ "Toxic oil syndrome", "Progressive systemic sclerosis", "Sickle cell anaemia", "Argemone mexicana poisoning" ]
D
Argemone mexicana poisoning results from use of edible oils adulterated with argemone mexicana seed oil the clinical condition is known as epidemic dropsy. Sanguinarine and dihydrosanguinarine are two major toxic alkaloids of argemone oil, which cause widespread capillary dilatation, proliferation and increased capilla...
train
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A man takes peanut and develops, tongue swelling, neck swelling, stridor, hoarseness of voice. What is the probable diagnosis.
[ "Angioneurotic edema", "FB bronchus", "Parapharyngeal abscess", "FB in larynx" ]
A
A i.e. Angioneurotic edema
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Adenovirus 40/41
[ "Cervical tissue", "Synovial fluid", "Blood", "Stool" ]
D
The diagnosis of a viral infection is made easier by the creation of a greater number of diagnostic virology laboratories during the past few decades. In order for viral diagnosis to be successful, the most appropriate specimen must be collected for the disease in question.Many viruses can be isolated from feces. Of th...
train
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Awareness of having a disease is
[ "Insight", "Perseveration", "Delusion", "Incoherence" ]
A
Ans. a (Insight). (Ref. Psychiatry by Niraj Ahuja, 5th ed., 14, 41, 57, 72, 85, 95, 171)Term DefinitionPerseverationis persistent repetition of words beyond their relevance.Verbigerationis senseless repetition of same words or phrases.Delusionsare false unshakable belief in something that is not true.Insightis awarenes...
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All except one are true regarding Barret'soesophagus
[ "More incidence of sq. cell ca", "Metaplasia", "Columnar epithelium", "Involves lower oesophagus" ]
A
Ans is 'a' ie More incidence of sq. cell ca There is increased incidence of adenocarcinoma in Barret's esophagus.Barrett's esophagus is a premalignant condition with increased incidence of adenocarcinoma of esophagus. The risk of adenocarcinoma increases with increasing length of columnar-lined epitheliumAlso rememberB...
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The distal end of humerus develops from how many centers?
[ "2", "3", "4", "5" ]
C
Ossification centers are capitulum with the lateral pa of the trochlea, the medial pa of the trochlea, and one for each epicondyle. The center for the medial epicondyle forms a separate epiphysis whereas the centers for the lateral epicondyle, capitulum and trochlea fuse around pubey and form the composite epiphysis.Ab...
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A 15 year old male presents with hematuria. he has previous diagnoses of deafness and corneal dystrophy. Urinalysis shows I + proteins, no ketones, no glucose, 1+blood, and no leukocytes. A renal biopsy reveals tubular epithelial foam cells by light microscopy. By electron microscopy the glomerular basement membrane sh...
[ "Acute tubular necrosis", "Berger disease", "Membranous glomerulonephritis", "A 1po syndrome" ]
D
Ans. is 'd' i.e., Alpo syndromeo Glomerulonephritis, deafness, corneal dystrophy with foam cells and attenuation of GBM suggest the diagnosis of Alpo syndrome.
train
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Renal parenchyma derived embryologically from?
[ "Pronephros", "Metanephros", "Mesompehros", "Cloaca" ]
B
Development of Kidney: Secretory pa of kidney:derived from metanephrons/metanephric blastyma Collecting pa of kidney:derived from ureteric bud
train
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A common cause of Primary hyperparathyroidism is
[ "Multiple parathyroid adenomas", "Solitary parathyroid adenoma", "Adrenal hyperplasia", "Ectopic PTH production" ]
B
null
train
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Bilateral parotid gland enlargement is seen in all of the following except:
[ "Sarcoidosis", "SLE", "Chronic pancreatitis", "Sjogern's syndrome" ]
B
Answer is B (SLE): Parotid enlargement is not a feature of SLE
train
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True regarding hemobilia
[ "Triad of jaundice, pain, Melena", "MC cause : rupture of poal vein into biliary system", "MR angiography is the IOC", "None of the above" ]
A
Clinical features of Hemobilia Characterised by Quinck's triad (Sandblom's triad) : GI hemorrhage +biliary colic +jaundice Presentation: Melena (90 %), hemetemesis (60%), biliary colic (70%), and jaundice (60%). Tendency for delayed presentation (upto weeks) and recurrent brisk but limited bleeding over months and even...
train
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The calorie content (per 100 ml) of term human milk is:
[ "67", "77", "87", "97" ]
A
Ans. A. 67The calorie intake of term human milk is 67calorie/100ml. Other components of term human milk are:Protein: 1.1g/100mlFat: 4.5gm/100ml
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Afferents to basal ganglia rests in
[ "Striatum", "Globus pallidus", "Striatum", "Subthalamus nuclei" ]
A
The main inputs to the basal ganglia terminate in the striatum. They include the excitatory coicostriate pathway from M1 and premotor coex. There is also a projection from intralaminar nuclei of the thalamus to the striatum (thalamostriatal pathway).Ref: Ganong's Review of Medical Physiology, Twenty-Third Edition.
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For chemotherapy induced vomiting, 5HT3 antagonist having maximum potency is:
[ "Ondansetron", "Granisetron", "Dolasetron", "Palonosetron" ]
D
it is the longest acting and highest affinity towards 5HT3 receptor used in chemotherapy induced vomiting ESSENTIAL OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PG NO .669
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Selection criteria for ASHA are all except -
[ "Woman", "Resident of village", "Education upto class five", "Literate" ]
C
Ans. is 'c' i.e., Education upto class five Accredited Social Health Activist (ASHA)o ASHA is the central component of the National Rural Health Mission (NRHM)o One of the key components of the National Rural Health Mission is to provide every village in the country with a trained female community health activist - 'AS...
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30 years of women comes with dysphagia for both solid & liquids. Barium swallow shows Parrot beak appearance. On esophageal manometry, increased LES pressure. Management includes:
[ "Nitrates", "Ca channel blockers", "Botulinum toxin", "All" ]
D
Ans. is all
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CCK-PZ causes all of the following except :
[ "Gall bladder contraction", "Pancreatic enzyme secretion", "Increased gastrin secretion", "Decreased lower esophageal sphinictor" ]
C
C i.e. Increased gastrin secretion
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Corneal sensation is lost in
[ "Herpes simplex", "Conjunctivitis", "Fungal infection", "Trachoma" ]
A
A i.e. Herpes simplex Decreased corneal sensations, dendritic and geographical ulcers are characteristic features of Herpes simplex ocular disease Q Sensory supply of cornea is through trigeminal nerve Q. Neurotrophic keratopathy occurs due to paralysis of sensory supply of cornea. Causes of neurotrophic keratopathy or...
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Serine is produced in human from -
[ "Glycine", "Methionine", "Homocysteine", "Homoserine" ]
A
Ans. is 'a' i.e., GlycineSerine is conveed to glycine and after that its metabolism is similar to glycine. Conversion of serine to glycine is reversible reaction; therefore, serine is synthesized also from glycine.
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Treatment of SVC syndrome due to Small Cell Carcinoma Lung is
[ "Radiotherapy", "Surgery", "Chemotherapy", "No treatment" ]
B
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The most common underlying anomaly in a child with recurrent urinary tract infection is:
[ "Posterior urethral valves", "Vesicoureteric reflux", "Neurogenic bladder", "Renal calculi" ]
B
* 30-35% children with UTI have VUR Recurrent UTI are observed in 30-50% children, usually within 3 months of the first episode. Predisposing factors for recurrent UTI include female sex, age below 6 months, obstructive uropathy, severe vesicoureteric reflux (VUR), habitual postponement of voiding (voiding dysfunction)...
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Female patient with bilateral hilar lymphadenopathy and joint pain. ACE levels are elevated. Diagnosis is?
[ "Sarcoidosis", "Silicosis", "Hodgkins lymphoma", "Non Hodgkins lymphoma" ]
A
Ans. (a) SarcoidosisRef.: Harrison 19th ed. / 2206Lofgren syndrome symptoms consist of fever, bilateral hilar lymphadenopathy (BHL), and polyarthralgias
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Multiple sclerosis is characterized by a loss of which lipids
[ "Phospholipids and ceramide", "Sphingolipids and ceramide", "Sphingolipids and gangliosides", "Phospholipids and sphingolipids" ]
D
Phospholipids and sphingolipids Ceramide is an impoant signaling molecule for apoptosis and is a precursor for glycosphingolipids and gangliosides. Sphingolipids and phospholipids are structural lipids in membranes. Multiple sclerosis is a demyelinating disease in which both phospholipid and sphingolipid levels are dec...
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A patient comes to you complaining that whenever he takes aspirin for headache, he develops severe shortness of breath. Which of the following may be partly responsible for this effect ?
[ "Leukotrienes", "Prostaglandin E", "Thromboxane A2", "Prostacyclin" ]
A
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In reflux nephropathy, glomerular lesion is-
[ "Focal GN.", "Membranous G.N.", "Membrano proliferative G.N.", "Minimal change disease" ]
A
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In case of sudden death in a young football player, the first clinical suspicion would rest on which of the following differentials ?
[ "Arhymogenic right ventricular dysplasia", "Takotsubo cardiomyopathy", "Atrial septal defect", "Eisenmenger complex" ]
A
Answer- A. Arhymogenic right ventricular dysplasiaThe most impoant cause of sudden death in professional footballer in setting of beta myosin testing being available is not HOCM but arrythmogenic right ventricular dysplasia.The Desmin gene irresponsible for defect in muscle of right ventricle leading to fibrofatty repl...
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Ion which promotes glucose absorption in the gut region: September 2007
[ "CI ?", "K+", "Na+", "Ca2+" ]
C
Ans. C: Na+Glucose enters cells by facilitated diffusion or, in the intestine and kidneys, by secondary active transpo with Na+. In muscle, fat, and some other tissues, insulin facilitates glucose entry into cells by increasing the number of glucose transpoers in the cell membranes.The glucose transpoers that are respo...
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Of the total oxygen consumed by the body (per min.), greatest fraction is consumed by:
[ "Liver", "Brain", "Muscle", "kidney" ]
A
Under resting conditions, total O2 consumption by the body = 250 ml/min. Greatest fraction of this O2 consumption is by the liver Liver - 30% or 75 ml/min. Muscle consumes 20% or 50 ml/min. Brain consumes 18% or 45 ml/min. In terms of per 100 gm of tissue per min., highest O2 consumption is by the hea - 8 ml/100 gm/min...
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The most potent HMG-coA reductase inhibitors is
[ "Simvastatin", "Atorvastatin", "Rosuvastatin", "Pitavastatin" ]
D
Refer kDT 7/e p 637 The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-CoA) reductase inhibitors, also known as statins, are the most effective class ofdrugs for lowering serum low-density lipoprotein cholesterol (LDL-c) concentrations
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Which one of the following is characteristic of mitral valve prolapse syndrome -
[ "Rough mid diatolic murmur", "Collapsing pulse", "Lound first hea sound", "Mid systolic click" ]
A
Early diastolic murmurs sta at the same time as S2 with the close of the semilunar (aoic & pulmonary) valves and typically end before S1. Common causes include aoic or pulmonary regurgitation and left anterior descending aery stenosis. Mid-diastolic murmurs sta after S2 and end before S1. They are due to turbulent flow...
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All of the following is/are true regarding candidiasis:
[ "Commonly involve mucosa & skin", "Not involve nails", "Caused by yeast like fungus", "Diabetes is most impoant risk factor" ]
B
Ans: (B) Not involve nails.It is an infection of skin, mucosa & rarely of internal organsIt is caused by yeast like fungus, Candida albicans & occasionally by other candida speciesUbiquitous in nature, these organisms are found on inanimate objects, in foods, and on animals and are normal commensals of humans. They inh...
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Rubella virus was isolated in-
[ "1862", "1912", "1932", "1962" ]
D
Rubella virus was isolated in 1962. In 1967, an attenuated vaccine was developed. Ref:PARK&;S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 23rd edition , Page: 150
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The lower esophageal sphincter (LES) resting pressure is:
[ "5-10 mm Hg", "10-15 mm Hg", "15-25 mm Hg", "None of the above" ]
C
The LES measures 3-4 cm in length and its resting pressure ranges between 15 and 24 mm Hg. At the time of swallowing, the LES relaxes for 5-10 seconds to allow the food bolus to enter the stomach, and then it regains its resting tone
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Vitreous hemorrhage produces ?
[ "Sudden painless loss of vision", "Sudden painful loss of vision", "Gradual painless loss of vision", "Gradual painful loss of vision" ]
A
Ans. is 'a' i.e., Sudden painless loss of vision
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A 60-year-old man with diabetes mellitus presents with painless, swollen right ankle joint. Radiographs of the ankle show destroyed joint with a large number of loose bodies. The most probable diagnosis is -
[ "Charcot's joint", "Clutton's joint", "Osteoarthritis", "Rheumatoid arthritis" ]
A
Painless swollen ankle, destroyed joint and multiple loose bodies in a diabetic patient suggest the diagnosis of Charcot’s joint (neuropathic joint). Joint destruction without pain is characteristic of Charcot’s joint.
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Commonest intra-abdominal tumour below 2 years ?
[ "Neuroblastoma", "Wilm's tomour", "Hepatoblastoma", "Lymphomaeoplasia" ]
A
Ans. is 'a' i.e., Neuroblastoma "Of all childhood neoplasms, Neuroblastoma is exceeded in frequency only be leukemia and brain tumors."-CSDT
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Hyphaema i.e. blood in the anterior chamber is suggestive of
[ "Intraocular trauma", "Posterior uveitis", "Capillary hemangioma of the lid", "High grade myopia" ]
A
Answer- A. Intraocular traumaEtiologyof hnhaemaThe most common causes of hyphema are intraocular surgery, blunt trauma, and lacerating trauma.Hyphemas may also occur spontaneously, without any inciting trauma
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A inhalation anaesthetic agent was used in a surgery which caused high output renal failure. The agent is:
[ "Methoxyflurane", "Diethyl ether", "Enflurane", "Halothane" ]
A
Methoxyflurane was the most potent inhalation agent, but its high solubility and low vapor pressure yielded longer inductions and emergences. Up to 50% of it was metabolized by cytochrome P-450 (CYP) enzymes to free fluoride (F-), oxalic acid, and other nephrotoxic compounds. Prolonged anesthesia with methoxyflurane wa...
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Low bih weight is defined as -
[ "Weight < 2.5 kg", "Weight < 2.0 kg", "Weight < 1.5 kg", "Weight < 10 percentile for their gastational age" ]
A
Ans. is 'a' i.e., Weight < 2.5 kg
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Which of the following serum levels of lithium is therapeutic ?
[ "0.1-0.4 mmol/L", "0.5-0.7 mmol/L", "0.8-1.1 mmol/L", "L2-1.5 mmol/L" ]
C
Ans. is 'c' i.e., 0.8-1.1 mmol/L Prophylactic level of lithium in bipolar disorder is 0.5-0.8 mEq/L and therapeutic level in acute mania is 0.8-1.2 mEq/L.
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Recurrent dislocation are common in :
[ "Shoulder", "Patella", "Hip joint", "Elbow joint" ]
A
Ans. is 'a' shoulder [Ref. Maheshwari, 3/e, p76 (2/e, p75)Commonest joint in the human body to dislocate- shoulder*Commonest joint in body to undergo recurrent dislocation- shoulder*Commonest type of shoulder dislocation- Anterior*
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Efficacy of new drug A is compared with an existing drug B in:
[ "Clinical trial phase I", "Clinical trial phase II", "Clinical trial phase III", "Clinical trial phase IV" ]
C
Phase Unit of study Purpose PRECLINICAL PHASE Lab experiments Animals Pretesting CLINICAL PHASE Typical No. of patients Phase 0 Healthy human volunteers Micro - dosing Phase I Healthy human volunteers Safety and non - toxicity profile 10 to 30 usually healthy volunteers Phase II Patients Effectiveness Fewer than 100 Ph...
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A patient of 8years-old attends your clinic he has class I incisor relation upper and lower incisors shows slight crowding. Right upper and left lower primary first molars recently extracted due to caries line of treatment is
[ "Extraction of Left upper and right lower primary first molars to relieve crowding", "Extract all primary canines to relive crowding", "Fix space maintainers", "Await until premolar erupt" ]
A
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