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Non ischaemic chest pain is caused by:
[ "Bleomycin", "Vincristin", "Cyclophophamide", "Cisplatin" ]
A
Ans: aRef: Harrison, 15"'ed, p. 434, Table 71.2 VI
train
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Stimulates the production of IGF.
[ "LH", "PRL", "TSH", "GH" ]
D
GH stimulates the release of IGF by the liver and other tissues. The other hormones listed do not stimulate IGF release from any tissue.
train
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Function of the maxillary sinus is:
[ "Protects the skull against mechanical shock.", "Defence against bacterial infection.", "It warms and moistens the inspired air.", "All of the Above." ]
D
Functional Importance and Clinical Considerations Many functions are attributed to maxillary sinus. Being an air space it lessens the weight of skull, gives resonance to the voice and protects the skull against mechanical shock. It warms and moistens the inspired air. The lysozyme it produces is bactericidal and thus c...
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ADHD in childhood can lead to which of the following disorder in future?
[ "Schizophrenia", "Alcoholism", "Dissociative disorder", "Mental retardation" ]
B
ADHD can lead to substance abuse,mood disorders & antisocial personality disorder in the future.
train
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Which of the following would be expected to contain relatively high numbers of functional hematopoietic cells?
[ "Adult liver", "Umbilical cord blood", "Adult circulating blood", "Adult spleen" ]
B
Ans. B. Umbilical cord blooda. Umbilical cord blood, derived from the circulating blood of newborn infants, possesses high levels of hematopoietic progenitors.b. Levels of circulating progenitors rapidly decrease after birth, depleting the progenitor content within the circulating blood of adults.c. The spleen of adult...
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Size of znpo4 used for luting?
[ "25 Microns", "40 Microns", "45 microns", "15 Microns" ]
A
null
train
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TMJ development starts at:
[ "2 weeks", "10 weeks", "29 weeks", "25 weeks" ]
B
Three phases in the development of the TMJ were identified: The first is the blastematic stage (weeks 7-8 of development), which corresponds with the onset of the organization of the condyle and the articular disc and capsule. During week 8, intramembranous ossification of the temporal squamous bone begins.  The secon...
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Which is NOT a feature of polymyositis?
[ "Pharyngeal muscle involvement", "Gottron's rash", "Proximal muscle involvement", "Pain in limbs" ]
B
Answer is B (Gottron's rash) : Gottron's rash is a feature of dermatomyositis and is characterized by erythema of knuckles witlz raised violaceous scaly eruptions. No rash is seen in patients of polymnyositis Polymyositis is essentially a diagnosis of exclusion Polymyositis is a subacute inflammatory myopathy affecting...
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Most important factor in management of precclampsia:
[ "Severtiy of hypertension", "Proteinuria", "Convulsions", "Pedal edema" ]
A
null
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ORS new osmolarity is -
[ "270", "245", "290", "310" ]
B
Ans. is 'b' i.e., 245 o Because of the improved effectiveness of reduced osmolarity ORS solution, WHO and UNICEF are recommending that countries manufacture and use the following formulation in place of the previously recommended ORS solution.Composition of reduced osmolarity ORSReduced osmolarity ORSgrams/litreSodium ...
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A 68 year old man with a history of very severe COPD (FEV1~1.0L, <25% predicted) presents to the ER complaining of worsening dyspnea and an increase in the frequency and purulence of his sputum production over the past 2 days. His oxygen saturation is 78% on room air. Before he is placed on supplemental oxygen, a room ...
[ "Respiratory acidosis uncompensated", "Respiratory acidosis paially compensated", "Metabolic acidosis uncompensated", "Metabolic alkalosis paially compensated" ]
B
pH- 7.25 (acidic) PCO2 - 68 mm Hg (respiratory acidosis) HCO3 - 31 mm Hg (elevated) - but pH acidic - So paially compensated
train
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Principal serum enzyme used in clinical diagnosis of Wilson disease
[ "Aspaate aminotransferase", "Ceruloplasmin", "b-Glucoscerebrosidase", "Lactate dehydrogenase isozyme 5" ]
B
Serum enzymeDiseaseAspaate aminotransferase(AST, or SGOT)Myocardial infarctionAlanine aminotransferase(ALT, or SGPT)Viral hepatitisAmylaseAcute pancreatitisCeruloplasminHepatolenticular degeneration(Wilson disease)Creatine kinaseMuscle disorders and myocardialinfarctiong-Glutamyl transferaseVarious liver diseasesLactat...
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Most common cells of connective tissue are:
[ "Fibrobalst", "Plasma cells", "Basal cells", "Histiocytes" ]
A
null
train
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Field carcinogenesis theory is commonly seen in
[ "Head and neck cancer", "Prostate cancer", "Cervical cancer", "Breast cancer" ]
A
Smoking causes diffuse epithelial injury in the oral cavity, neck, esophagus and lung. Patients cured of squamous cell cancers of the lung and esophagus, oral cavity and neck are at risk (as high as 5% per year) of developing second cancers of the upper aerodigestive tract. Cessation of cigarette smoking does not marke...
train
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Low risk type of HPV
[ "Type-16", "Type-6", "Type-18", "Type-31" ]
B
<p>HPV Human papilloma virus More than 200 types known .100 have been sequenced. These virus invade squamous epithelium and trigger cell proliferation. Viruses mainly being transmitted by fomites ,scratching, and auto inoculation. Low risk type-6 and 11 {Reference: IADVL textbook of dermatology, vishalakshi Vishwanath ...
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Agent which dissolves rubber –
[ "Halothane", "Enflurane", "Desflurane", "Isoflurane" ]
A
Halothane and methoxyflurane are absorbed by rubber.
train
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Make the diagnosis of a 26 day old Infant presenting with recurrent nonbilious vomiting with costipation and loss of wt?
[ "Oesophageal atresia", "Choledochal cyst", "Ileal atresia", "Pyloric stenosis" ]
D
Ans is 'd' ie Pyloric stenosis This is a typical picture of pyloric stenosis a) Infant presenting in 4th week b) Non-bilious vomitting. c) With constipation and wt. loss. Lets see other options. Esophageal atresia a) Infant presents soon after bih with complaints of regurgitation of milk, saliva pours almost continuous...
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A patient presents with pain and paresthesia on the palmar surface of the lateral poion of the hand and the palmar surface of the first three digits. Through which of the following muscles does the nerve that supplies this region pass?
[ "Coracobrachialis", "Flexor carpi ulnaris", "Flexor digitorum superficialis", "Pronator teres" ]
D
The median nerve provides sensory innervation to the skin of the lateral poion of the palmar surface of the hand and to the skin of the palmar surface of the first three and one-half digits. After the median nerve crosses the elbow to enter the forearm, it passes between the two heads of the pronator teres muscle. The ...
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Hydrostatic test is used to determine -
[ "Presence of smegma", "Live birth", "Criminal abortion", "Buccal coitus" ]
B
Ans. is 'b' i.e., Live birth * Has been explained in previous sessions
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According to Organ Transplantation Act 1994, what is the punishment for doctor if found guilty?
[ "1 year", "More than 5 years", "2-5 years", "2 years" ]
B
Punishments under Organ Transplantation Act 1994: – For medical practitioners involved: Removal of name for 2 years from Medical register (and permanent removal for any subsequent offence) – For other persons involved: Five years imprisonment + Fine up to ` 10,000/ • New Modification in 2011: Punishment for persons inv...
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For hysteroscopy, following are/is used:a) Distilled Waterb) Airc) Glycined) CO2
[ "ab", "cd", "bd", "ac" ]
B
null
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Sequence of colour changes observed in Raynaud's disease.
[ "Red, blue, white", "White, blue, red", "Blue, red, white", "White, red, blue" ]
B
Triphasic Color Response Include Three Stages Blanching (stage of local syncope) With exposure to cold, digital aerioles goes into spasm Decreased flow is evidenced by pallor or blanching Digits may appear white Cyanosis (stage of local asphyxia) Capillaries and venules dilate Red Engorgement (stage of recovery) With r...
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Lid retraction is caused by ?
[ "Bimatoprost", "Latanoprost", "Brimonidine", "Apraclonidine" ]
D
Points to remember - Apraclonidine Sympathomimetic drug Indication - Open-angle Glaucoma Mechanism of action - Decrease aqueous secretion Adverse effect - Upper lid retraction, eye allergy.
train
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MDR tuberculosis is defined by -
[ "Resistance to all first and second line anti-tubercular agents", "Resistance to any three first line anti-tubercular agents", "Resistance to all first line and any three classes of second line anti-tubercular agents", "Resistance to isoniazid and rifampicin" ]
D
Ans. is 'd' i.e., Resistance to isoniazid and rifampicin o MDR is defined as resistance INH and rifampicin with or without resistence to other drugs. XDR is defined as resistance to INH and rifampicin as well as to all fluoroquinolones and one of injectable drugs (capreomycin, kanamycin, amikacin).
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Carey coomb murmur is seen in
[ "Severe mitral stenosis", "Acute rheumatic carditis", "Pure aoic regurgitation", "Severe pulmonary HT" ]
B
Answer is B (Acute Rheumatic carditis) Carey coombs murmur is delayed diastolic murmur seen in acute rheumatic carditis and is attributed to excessive left atrial blood flow due to mitral regurgitation. It is not seen in MR, AR or severe pulmonary Hypeension.
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The glomus tumor invasion of jugular bulb is diagnosed by
[ "Carotid angiography", "Veebral venousvenography", "X-ray", "Jugular venography" ]
D
MRI - gives soft tissue extent of tumor; Magnetic Resonance Angiography (MRA) shows compression of the carotid aery whereas magnetic resonance venography shows invasion of jugular bulb by the tumor.
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All of the following act through GABA except ?
[ "Phenobarbitone", "Carbamazepene", "Zopiclone", "Muscimol" ]
B
Ans. is 'b' i.e., Carbamazepene
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Traumatic dislocation of epiphysial plate of femur occurs -a) Mediallyb) Laterallyc) Posteriorlyd) Rotationallye) Anteriorly
[ "ab", "bc", "acd", "abc" ]
D
Traumatic separation of distal femoral Epiphysis Overall this injury is rare; However, of all the injuries of epiphysis, injuries of the distal femoral epiphysis have the highest incidence of post-traumatic growth arrest. These injuries are described according to the direction of displacement of the epiphysis and the...
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Genetic syndromes associated with increased incidence of neuroendocrine tumors are all except:
[ "Multiple endocrine neoplasia 1", "Von hippel Lindau disease", "Von recklinghausen's disease", "Cri du chat syndrome" ]
D
Multiple endocrine neoplasia 1, Von hippel Lindau disease, Von recklinghausen's disease and Tuberous sclerosis are the genetic syndromes associated with increased incidence of neuroendocrine tumors. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 3060
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A 20 year old man has presented with increased alcohol consumption and sexual indulgence, irritability, lack of sleep, and not feeling fatigued even on prolonged periods of activity. All these changes have been present for 3 weeks. The most likely diagnosis is -
[ "Alcohol dependence", "Schizophrenia", "Mania", "Impulsive control disorder" ]
C
Diagnostic criteria for mania Three or more of the following for at least 1 week:- Inflated self esteem or grandiosity     Decreased need for sleep        Overtalkativeness   Flight of ideas Distractibility Psychomotor agitation or Increased goal-directed activities Excessive involvement in pleasurable activities ...
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Mineral oils are used in mosquito control measure as -
[ "A personal protection method", "Larvicide", "Adulticide", "Space spray" ]
B
Mineral oils are used as chemical control against mosquito larvae. The mineral oil application to water is the oldest method to control mosquito. oils used are diesel oil, fuel oil, kerosene oil, and crude oils. Special mosquito larvicidal oils are also available. Oil kills larvae and pupae within a sho time after appl...
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True about Multiple myeloma are all Except:
[ "Bence Jones protein in urine", "Hypogammaglobulinemia", "Amyloidosis", "Plasmacytosis < 10%" ]
D
Answer is D (Plasmacytosis < 10%) Multiple myeloma is characteristically associated with Plasmacytosis >10%. Multiple myeloma may be associated with both Hypogammaglobulinemia and Hypergammaglobulinemia. Electrophoresis Pattern in Multiple Myeloma Monoclonal Hypergammaglobulinemia (M spike) This is the characteristic e...
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Ehrlich phenomenon is seen in -
[ "Myobacterium T.B.", "Proteus", "Staphylococcus", "Corynebacterium" ]
D
null
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Not major criteria for diagnosis of neurocyst- icercossi ?
[ "Detection of cysticerci antigen by ELISA", "Detection of cysticerci antigen by immunoblot", "Cystic lesion in brain parenchyma by MRI", "Calcified lesion in brain parenchyma by CT" ]
A
Diagnostic criteria for human evsticercosis
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Immunoglobulin that is inactive at high temperature is?
[ "IgG", "IgA", "IgM", "IgE" ]
D
IgE is heat liable ie, inactivated when heated from 5 min up to1 hr at 56 degrees. Reff: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:99
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Delayed puberty in female-
[ "No breast budding in 10 years", "Menarche > 16 year", "menarche > 1 year of brean budding", "FSH < 20 in 16 year" ]
B
Ans. is 'b' i.e., Menarche Delayed PubertyMore common in boy than girlMost common cause in constitutional delayGirls-Delayed puberty is defined asLack of secondary sexual character by age of 17 yearsAbsence of menarche by age of 16 year5 year a fter pubertal onset.Boys-Lack ofpubertal changes by the age of 14 years.
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Treatment of pustular psoriasis is –
[ "Thalidomide", "Retinoids", "Hydroxyurea", "Metholtrexate" ]
B
First choice for pustular psoriasis     →  Retinoids (Acitretin) Second choice for pustular psoriasis    → Methotrexate
train
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Rotameters
[ "Depend on laminar low for their accuracy", "Will only function when upright", "Are constant pressure drop-constant orifice devices", "Are not accurate below 1L/min" ]
B
Rotameters are constant pressure drop-variable orifice devices. They are accurate at values as low as 200mL/min both laminar and turbulent flow determine their accuracy .
train
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Abnormal excretory function of hepatocytes assessed by -a) Increased PTb) Increased ALTc) Increased Alkaline Phosphatased) Increased gamma GT
[ "cd", "bc", "bd", "ac" ]
A
null
train
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Which of the following is TRUE about manic-depressive psychosis?
[ "Cyclothymic disorder consists of mania and less severe episodes of depression", "Psychosocial stressors have no influence on manic episodes", "Hypehyroidism causes rapid-cycling bipolar disorder in females", "Mood disorders often have seasonal patterns" ]
D
Mood disorders often have seasonal patterns. Acute episodes of depression are common in spring and fall, whereas mania appears to cluster in the summer months. Suicide rates also show a peak in the spring and a (smaller) peak in the late fall. Higher rates of hypothyroidism, greater use of antidepressant medication, an...
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The angle's system of classification of malocclusion was modified by:
[ "Simon", "Dewey's", "Lischer", "Ackerman Profit" ]
B
null
train
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Nipah virus is associated with epidemics of:
[ "Hepatitis", "Encephalitis", "Pneumonia", "All of the above" ]
B
Nipah virus is a zoonotic virus that causes outbreaks of fatal encephalitis. Outbreak occurred in West Bengal in 2001 Ref: National Health Programmes in India, J.Kishore, 10th edition pg: 391
train
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Which aery does not contribute to Little's area
[ "Septal branch of facial aery", "Anterior ethmoidal aery", "Sphenopalantine aery", "Posterior ethmoidal aery" ]
D
LITTLE'S AREA (Anterior inferior pa of nasal septum) - Usual site for epistaxis in children. Four Aeries anastomose here and form Kiesselbach's Plexus. Anterior ethmoidal aery(Ophthalmic aery) Sphenopalatine(Maxillary aery) Septal branch of superior labial(Facial aery) Greater palatine aery(Maxillary aery) Ref: Dhingra...
train
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Nitroblue Tetrazolium reduction is used for finding out the following:
[ "Phagocytes", "Complement", "T-cell", "B-cell" ]
A
The initial laboratory screening for phagocyte disorders, mainly impaired neutrophil function, should include a CBC and cell differential to look for neutropenia. A blood smear can detect Howell-Jolly bodies in erythrocytes, indicative of asplenia, and abnormalities in lysosomal granules in neutrophils. An abnormality ...
train
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Stye is an acute suppurative infection of
[ "Gland of zeis", "Meibomian gland", "Both", "Lacrimal gland" ]
A
Stye or Hordeolum externum is an acute suppurative staphylococcal infection of gland of zeis or gland of moll.
train
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What is the mechanism of action of use of Naltrexone in alchohol addiction in a 45-year-old man?
[ "Inhibits metabolism of alcohol", "Blocks opioid receptors", "Affects GABA neurotransmitter system", "None of the above" ]
B
Naltrexone blocks opioid receptors and reduces craving for alcohol and opioids. It also reduces reward in response to drinking. Hence it is useful to prevent relapse in a de-addiction programme. Inhibits metabolism of alcohol: Disulfiran inhibits metabolish of alcohol and leads to accumulation of acetaldehyde. Affects ...
train
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Deltoid ligament is attached to all except -
[ "Medial malleolus", "Talus", "Calcaneum", "Lateral malleolus" ]
D
Medial collateral ligament/Deltoid ligament is attached from medial malleolus to -        Superficial part    Tibionavicular part- Navicular tuberosity and spring ligament    Tibiocalcaneal part- Sustenticulum tali    Posterior tibiotalar part- medial tubercle and medial surface of talus -        Deep part (Anterior ...
train
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The Hematopoietic syndrome results when acute whole-body radiation exposure is above
[ "50 rad", "100 rad", "200 rad", "400 rad" ]
C
The hematopoietic syndrome results from acute whole-body doses above 200 rads. A prodromal phase consists of nausea and vomiting within the first 12 hrs, with symptoms usually lasting up to 48 hrs. A latent period of 2-3 wks during which patients may feel quite well follows. Although patients are asymptomatic, bone mar...
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Sarcolemma is the cell wall surrounding:
[ "Neurons", "Muscle cells", "Red blood cells", "None of the above" ]
B
Each muscle fiber is a single cell that is multinucleated, long, cylindrical, and surrounded by a cell membrane, the sarcolemma. Ref: Ganong's Review of Medical Physiology 23rd edition, Chapter 45.
train
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Cells seen at the function between two layers ofplacenta are?
[ "Hofbauer cell", "Hofmann cells", "Amniogenic cells", "Uterine natural killer cells (UNK)" ]
A
Ans. is'a'i.e., Hofbauer cellHofbauer cells (HBCs) are placental macrophages that are present in the core of villus.Major cell type in placenta include syncytiotrophoblasts which line intervillous space and are in direct contact of maternal blood.Underlying stromal cells adjacent to fetal capillaries largely consisting...
train
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Refractive condition of the eye at birth is –
[ "Hypermetropia of 2D", "Myopia of 2 D", "Hypermetropia of 5D", "Myopia of 5D" ]
A
The newborn is usually hypermetropic by +2 to +3D.
train
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Tinea capitis is caused by all the following Except
[ "T. mentagrophytes", "T. verrucosum", "E. floccosum", "M. canis" ]
C
Trichophyton - involves skin, hair & nails Microsporum - spares nail Epidermophyton - spares hair Ref Harrison 20th edition pg 1212
train
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The “cutoff” value of plasma glucose in 50 g glucose challenge test is
[ "120 mg/dL", "140 mg/dL", "160 mg/dL", "180 mg/dL" ]
B
null
train
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Maximum cation concentration in ECF is of-
[ "K+", "Ca+2", "Cl-", "Na+" ]
D
Ans. is 'd' i.e., Na+ ComponentExtracellular fluid (ECF) (meq/1)Intracellular fluid (ICF) (meq/l)Na+K+C1-HCO3-Mg+2Ca+2PO4-21425.5103281[?]22[?]5414150410580 0001 75Protein (organic anion)5 (2g%)40 (16g %)
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The organism causing "Pseudomembranous" colitis:
[ "The organism causing \"Pseudomembranous\" colitis:", "Clostridium perfringens", "Clostridium tetani", "Clostridium botulinum" ]
A
Clostridium difficile
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A sewage worker presents to the Emergency depament with fever and jaundice. Laboratory findings reveal an elevated BUN and serum creatinine suggestive of renal failure. Which of the following antiboitics is recommended?
[ "Cotrimaxozole", "Erythromycin", "Ciprofloxacin", "Penicillin G" ]
D
Ans. is 'd' i.e. Penicillin G o Presence of fever, jaundice and renal failure in a sewage worker (contact with rat urine) suggests a diagnosis of Wen syndrome or Icterohemorrhageic fever caused by leptospirae. o Penicillin G (intravenously) is the recommended agent. "In severe illness, I.V benzyl penicillin is the drug...
train
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Glomus jugulare commonly arises from -
[ "Hypo tympanum", "Mesotympanum", "Epitympanum", "Prussaks space" ]
A
Ans. is 'a' i.e., Hypotympanumo There are two types of glomus tumors:-Glomusjugulare# These glomus tumors arise from the dome of the internal jugular vein in the hypotympanum and jugular foramen. In jugular foramen they can invade IX to XII cranial nerves.Glomus tvmpanicum# They arise from the promontory of the middle ...
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A Patient came with h/o itchy tense blisters whose roof settled as above. Shows big blisters on forearm which have subsided with the roof sticking to the floor without much damage. Diagnosis is
[ "Bullous pemphigoid", "Pemphigus vulgaris", "Dermatitis herpetiformis", "Steven Johnson syndrome" ]
A
.
train
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Aeriovenous fistula can safely be ligated if the following is positive:
[ "Allen's Test", "Henle-Coenen sign", "Tredelenberg test", "Schwaz Test" ]
A
Allen&;s Test: Tests the adequacy of the blood supply to the hand from the radial and ulnar aeries and the arcade between them. Allen&;s test is used to know the integrity of palmar arch (Patency of radial and ulnar aeries). If these are patent, AVF can be safely ligated. Method of Allen&;s Test Elevate the hand and ap...
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Nerve element of brachial arch are developed from
[ "Ectoderm", "Neural crest cells", "Endoderm", "Mesoderm" ]
B
Ref. Gray’s anatomy.  41st edition. Page. 449. Topic, Subtopic – Brachial arch, embryology Branchial or pharyngeal arches are masses of mesoderm covered by ectoderm and lined by endoderm. Within these masses, muscular and skeletal components develop, as well as aortic arches and nerve networks. The arches are separated...
train
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The item shown below is used to feed newborns born at what gestational age?
[ "27 weeks", "30 weeks", "33 weeks", "37 weeks" ]
C
c. 33 weeksThe given picture is that of a paladai, that can be used for feeding neonates born between 32-34 weeks gestation; Initial mode of feeding of a preterm neonate depends on gestational age at which baby is born
train
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The earliest manifestations of Chronic lead poisoning include:
[ "Colic and Constipation", "Encephalopathy", "Punctate basophilia", "Lower limb paralysis" ]
C
C i.e. Punctate basophilia
train
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Which among the following is TRUE about MIRENA?
[ "Levonorgestrel IUCD", "Hormonal implant", "Anti progesterone", "Used for MTP" ]
A
The levonorgestrel-releasing IUS, Mirena, releases 20 mcg of levonorgestrel per day and is approved for contraception for up to 5 years. It achieves local progestin concentrations that are ~1000-fold higher than systemic levels. It has many contraceptive actions including thickening of cervical mucous, inhibiting sperm...
train
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Which of the following is not a feature of dermatomyositis?
[ "'V' sign", "Holster sign", "Pokiloderma", "Groove sign" ]
D
Ans. is 'd' i.e., Groove sign * Groove sign (a depression along the course of a vein or between muscle groups) is seen in deep morphea.Cutaneous signs od dermatomyositisi) Gottron's papules: lilac or violaceous papules on knuckles and dorsa of handsii) Gottron's sign: violaceous erythema with edema over shoulders, arms...
train
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All the following antimicrobial agents are used topically except -
[ "Clotrimazole", "Griseofulvin", "Nystatin", "Miconazole" ]
B
Ans. is 'b' i.e., Griseofulvin o Griseofulvin is used systemically for dermatophytosis. It is ineffective topically.
train
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Exchange of trace evidence occurs, when a person comes in contact with other person. This principle is called:
[ "Locard's principle", "Quetelet's rule", "Petty's principle", "None of the above" ]
A
Locard's Principle of Exchange: It states that "When two objects come into contact with each other, there is always transfer of some material between them" This is helpful in crime investigations, especially in sexual offences.
train
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Electronic apex locator is used in Endodontics to determine the
[ "Root canal morphology", "Working length", "Pulp stone Location", "Pulp vitality" ]
B
null
train
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Glasgow coma scale includes all except
[ "Eye opening", "Verbal response", "Motor response", "Swallowing reflex" ]
D
null
train
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In a study to establish smoking as a risk factor for disease, 30 out of 50 smokers developed disease while as 10 out of 50 non smokers developed disease. The Odds ratio is:
[ "3", "5", "6", "10" ]
B
5
train
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True about influenza -
[ "Incubation period 2-3 weeks", "Most infections are subclinical", "Type-A virus causes Reye's syndrome", "Pandemic is caused by Type-B virus" ]
B
Ans. is 'b' i.e.. Most infections are subclinical Influenzao Influenza virus a RMA virus, belongs to orthomyxovirus.o There are three viral subtypes : i) Type A (causes all pandemics and most epidemics); type B: and type C (not circulating currently).o Currently the influenza viruses circulating in the world are : Ht N...
train
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Desmoglein 1 antibody in a patient with flaccid bulla and erosions on the face and trunk and sparing the mucosa is seen in ?
[ "Dermatitis Herpetiformis", "P vulgaris", "P foliaceous", "Bullous pemphigoid" ]
C
Pemphigus vulgaris (most common) Pemphigus foliaceous Clinical feature:- Early disease - Dsg3 (Mucosa) Late disease - Dsg3 > Dsg1(Skin) Dsg-1 Only Skin involvement Investigations - Histological: Row of tombstone appearance + + DIF + + Fish net like Pattern + + IgG Ab Dsg 3 > 1 Dsg 1
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Axonemes are associated with:
[ "Mitochondria", "Ribosome", "Peroxisome", "Cilia" ]
D
Within the cilium there is an axoneme that comprises a unique arrangement of nine outer microtubule doublets and two inner microtubules ("9+2" arrangement). Ref: Ganong's Review of Medical Physiology 23rd edition, Chapter 2.
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The antimicrobial agent which inhibits the ergosterol biosynthesis is
[ "Ketaconazole", "Amphotercin B", "5-flucytosine", "Grisefulvin" ]
A
Refer KDT 6/e 761 Azoles act by inhibiting an enzyme, lanosterol -14-alpha -demethylase. This enzyme is involved in formation of ergosterol Amphotercin B acts6by binding to ergosterol and forming pores in fungal cell membrane
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What is the treatment of threshold ROP ?
[ "Laser photocoagulation", "Slow reduction in oxygen", "Retinal reattachment", "Antioxidants" ]
A
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The medium of choice culturing yeast form of dimorphic fungi is -
[ "BHI", "SDA", "SDA with antibiotics , incubated at 37 degree celsius", "Any medium incubated at 35-37 degree celsius" ]
C
Dimorphic fungi: They exist as moulds (hyphal form) in the environment at ambient temperature (25degC) and as yeasts in human tissues at body temperature (37degC). Examples include: Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides, Paracoccidioides, Penicillium marneffei and Sporothrix schenckii. Brain he...
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Aschoff bodies in Rheumatic hea disease show all of the following features, except -
[ "Anitschkow cells", "Epitheloid cells", "Giant cells", "Fibrinoid necrosis" ]
B
Ans. is 'b' i.e., Epitheloid cell
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Tumors of the minor salivary glands are most frequently found at the:
[ "Upper lip.", "Lower lip.", "Palate.", "Tongue." ]
C
Palate is the most common site.
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Rituximab is used in all except
[ "NHL", "PNH", "RA", "SLE" ]
B
Ans. is 'b' i.e. PNH Cancer cells express a variety of antigen.These antigens can be targeted by certain antibodies which are specifically directed towards those antigens. The antigen antibody reaction leads to death of the cancer cells.Antibodies {monoclonal antibodies) are now being prepared by immunizing mice agains...
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Enzyme deficiency in albinism is:
[ "Tyrosinase", "Tyrosine hydroxylase", "Phenylalanine hydroxylase", "Homogentisate oxidase" ]
A
Ans. A. TyrosinaseAminoaciduriaEnzyme deficiencyAlbinismTyrosinasePhenyl KetonuriaPhenylalanine hydroxylaseAlkaptonuriaHomogentisate OxidaseHomocystinuriaCystathionine Beta SynthaseMaple syrup Urine DiseaseBranched Chain ketoacid Dehydrogenase
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Vitamin a dose in children of 1-6 years of age is
[ "50000 IU", "1 Lakh IU", "2 Lakh IU", "4 Lakh IU" ]
C
For treatment of vitamin A deficiency, oral vitamin A is given at a dose of 50000IU, 100000IU and 200000IU in children <6 months, 6-12 months and >1 year, respectively. The same dose is repeated next day and 4 weeks later.(Refer: Nelson's Textbook of Pediatrics, SAE, 1st edition, pg no. 320)
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Anti-inflammatory action of steroids due to
[ "Inhibiton of phospholipase A2", "Inhibhition of cyclooxegenase", "Increased activity of lipolipase", "Inhibition of lipo oxegenase" ]
A
PLA2 has been shown to promote inflammation in mammals by catalyzing the first step of the arachidonic acid pathway by breaking down phospholipids, resulting in the formation of fatty acids including arachidonic acid. This arachidonic acid is then metabolized to form several inflammatory and thrombogenic molecules. Exc...
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Type of hemicolectomy done for carcinoma appendix is-
[ "Right hemicolectomy", "Extended Right hemicolectomy", "Left hemicolectomy", "Extended left hemicolectomy" ]
A
Ans. is 'a' i.e., Right hemicolectomy o Carcinoids and adenocarcinomas of appendix may require right hemicolectomy.o Structures removed in right hemicolectomy :a. Caecum with appendixb. Ascending colonc. Hepatic flexured. Proximal transverse colone. Part of terminal ileumf. Fat and lymphnodes
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Hilar Lymph nodes showing egg shell calcification are seen in all accept?
[ "Sarcoidosis", "Aspergillosis", "Histoplasmosis", "Radiation induced mediastinal Lymphoma" ]
B
Egg shell calcification of Hilar Lymph nodes is not seen in Aspergillosis.
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Which of the following transcribe 5s rRNA?
[ "RNA Polymerase I", "RNA Polymerase II", "RNA Polymerase III", "None" ]
C
Eukaryotic RNA polymerase RNA synthesized Type I All RNA except 5s RNA Type II M RNA, mi RNA, inc RNA, Few sn RNA& sno RNA Type III 5s RNA , t RNA, few sn RNA & sno RNA Mitochondrial RNA polymerase Mitochondrial RNA
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Vasanti 45 years, was brought to casualty with abnormal movements which induced persistent detion of neck to right side. One day before she was prescribed Haloperidol 5mg three times daily from the psychiatry OPD. She also had an alternation with her husband recently. Which of the following is the most likely cause for...
[ "Conversion reaction", "Acute psychosis", "Acute drug dystonia", "CVA" ]
C
C i.e. Acute drug dystonia
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The most frequently implicated antibiotic among the causes of drug induced liver injury is:
[ "Tetracycline", "Amoxicillin-clavulanic acid", "Erythromycin", "Nalidixic acid" ]
B
Amoxicillin-clavulanic acid : The most frequently implicated antibiotic among cases of drug-induced liver injury. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560
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Non-reducing disaccharide is
[ "Sucrose", "Fructose", "Trehalose", "Lactose" ]
A
Repeated question
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The pathogenicity of E. histolytica is indicated by -
[ "Zymodeme pattern", "Size", "Nuclear pattern", "ELISA test" ]
A
Option 1, 2, 3 Zymodeme (isoenzyme) analysis: - E. histolytica possesses several isoenzymes like mailc enzyme, hexokinase, isomerase and phosphoglucomutase and these isoenzymes contribute in pathogenesis. When these isoenzymes are subjected to electrophoresis based on electrophoretic pattern (Zymodeme pattern) and mobi...
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Endodontics term was coined by
[ "Dr Grossman", "Dr Johnston", "Dr G.V. Black", "Dr Rochman" ]
B
null
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Punctuate yellow exudates in colon, found on endoscopic examiantion are indicative of
[ "Balantidium coli", "Ulceratice colitis", "Antibiotic colitis", "Gluten induced enteropathy" ]
C
null
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Stabilization of avulsed tooth requires:
[ "2 weeks", "3 weeks", "4 weeks", "More than 6 weeks" ]
A
Splinting Times
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In Addison's disease, the most diagnostic test is -
[ "Serum Na+,K+ renin", "S. Na+,K+, saline suppression", "Serum creatinine/urea ratio", "ACTH stimulation test" ]
D
The best method used for diagnosis of adrenal insufficiency is ACTH stimulation test. Addison's disease is produced due to deficiency of serum cortisol, but the measurement of these hormones is not the best way to diagnose addison's disease. Addison's disease is best diagnosed by ACTH stimulation test. The ACTH stim...
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Most common site for genital tuberculosis is
[ "Ovary", "Uterus", "Cervix", "Fallopian tube" ]
D
Fallopian tube
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Double bubble sign in children is seen in all EXCEPT:
[ "Ladds band", "Annular pancreas", "Pancreatic pseudocyst", "Diaphragmatic hernia" ]
D
* Obstruction of 2nd pa of duodenum cause 'double bubble' sign on plain abdominal radiograph * It may be due to- Annular pancreas, Pancreatic pseudocyst, Ladds band & tumor in head of pancreas.
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Lower leg perforators are named after
[ "Cockett", "Boyd", "Dodd", "May or kuster" ]
A
.
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The purpose of Randomised controlled trial
[ "To minimise the selection bias", "Most trials are inexpensive to run", "Most studies do not start with a null hypothesis", "False negatives and false positives are not possible" ]
A
(A) To minimise the selection bias # Randomized controlled trial (RCT) is a scientific procedure most commonly used in testing medicines or medical procedures.> RCTs are considered the most reliable form of scientific evidence because it eliminates all forms of spurious causality.> RCTs are mainly used in clinical stud...
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True about subendocardial haemorrhage is all except-
[ "May be seen after head injury", "Involves RV wall", "Continous pattern of sheet", "Flame shaped hemorrhages" ]
B
Subendocardial hemorrhages is a striking feature seen in many autopsy cases. It was believed to be an insignificant finding without any particular reference to the cause of death. However latest reports have indicated that presence of subendocardial hemorrhages is an indicator of exsanguination and head injury When sub...
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In donovanosis-
[ "Pseudolymphadenopathy", "Penicillin is used for treatment", "Painful ulcer", "Suppurative lymphadenopathy" ]
A
Ans. is `a' i.e., Pseudolymphadenopathy Donovanosis Caused by Calymmatobacterium granulomatis. C. granulomatis is ? - Gram negative - Encapsulated - Nonmotile - Intracellular It shares many morphologic and serologic characteristic (antigenic) and > 99% homology at the nucleotide level with Klebsiella. Clinical manifest...
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Society is defined as:
[ "A conglomeration people", "A group people bound with social norms", "An association with regulated membership", "An association patterned the norms of interaction" ]
B
Ans. is 'b' i.e A group of people bound with social norms "It is an organisation of member agents. The 'out standing' feature of society is a system - a system of social relationships between individuals. The importance of society lies in the fact that it controls and regulates the behaviour of the individual both by l...
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Viral enterotoxin is detected as a possible mechanism of pathogenesis in :
[ "Adeno virus", "Rota virus", "Calcivirus", "Astrovirus" ]
B
Mechanism of Rotavirus diarrhea : a. Rotavirus destroy mature enterocytes of proximal small intestine. Loss of absorptive villi and proliferation of secretory crypt cells – Secretory diarrhea Brush border enzymes are reduced so unmetabolized disaccharides accumulates resulting. – Osmotic diarrhea b. NSP4 = enteroto...
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