type string | sequence string | canonical_smiles string | pKd_value float64 | label int64 | buffer string | origin string | source string |
|---|---|---|---|---|---|---|---|
DNA | GGGACGACGGAGGTGTAGGGTTTAGGTAGTGGGTTGAAGTCGTCCC | C=C1CCC=C(C)CCC2C1CC2(C)C | 7.251812 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | GGGACGACGGCCCCTTTTAAGGAGGTAGAGGTGTTCGCTGTCGTCCC | Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F | 7.69897 | 1 | PBS (pH 7.4)- 8.1 mM Na2HPO4, 1.5 mM KH2PO4, 138 mM NaCl, 2.7 mM KCl, & 1 mM MgCl2 | Alkhamis O. & Xiao Y. (2022). Systematic Study of in Vitro Selection Stringency Reveals How To Enrich High-Affinity Aptamers. Journal of the American Chemical Society, 145(1) https://doi.org/10.1021/jacs.2c09522 | AptaGen |
DNA | GGGACGACTGGGGGTAGGTAAGGTTGGTTCTTGTGAGGTCGTCCC | Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F | 4.59176 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | GGGACGACATCGTAGGGGCACACGCTTAACGGGCTGATGTCGTCCC | Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F | 4.562249 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC | OCC1OC(O)C(O)C(O)C1O | 7.886057 | 1 | Shinkai's receptor 50uM with 2% methanol. | Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058 | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | CNC(C)C1CCC(N)C(OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O)O1 | 7.651695 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | CNC(C)C1CCC(N)C(OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O)O1 | 7.573489 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
DNA | CTCTCGGGACGACAGCCGAGTTGATTCAACAGCCGAGTCGTCCC | OCC1OC(O)C(O)C(O)C1O | 8.30103 | 1 | Shinkai's receptor 50uM with 2% methanol. | Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058 | AptaGen |
DNA | GGAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCG | COP(=O)(OC)OC=C(Cl)Cl | 9.070581 | 1 | 10 mM Tris, 10 mM MgCl2, 50 mM KCl, 25 mM NaCl, pH 7.5 | Chatterjee, B., Kalyani, N., Anand, A., Khan, E., Das, S., Bansal, V., … Sharma, T. K. (2020). GOLD SELEX: a novel SELEX approach for the development of high-affinity aptamers against small molecules without residual activity. Microchimica Acta, 187(11). doi:10.1007/s00604-020-04577-0 | AptaGen |
DNA | GGGACGACGGGGATTCGCGGATTCATGGAAAAGGGCTCGTCTGTCGTCCC | CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5 | 4.686133 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | COP(N)(=S)Oc1ccccc1C(=O)OC(C)C | 6.080922 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | COP(N)(=S)Oc1ccccc1C(=O)OC(C)C | 6.045757 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | CGCATACCAGCTTAGTTCAGAATTCATTGGAGCGTGGCGTGGATGCCCGATGGACCGCCCCAGGGTGCAGATAGTAAGTGCAATCTCGGC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O | 7.130768 | 1 | 50% 100 mM sodium chloride, 20 mM tris-hydrochloride, 2 mM magnesium chloride, 5 mM potassium chloride, and 1 mM calcium chloride (pH 7.6); 50% 1X Cut Smart Buffer (New England Biolabs) 50 mM potassium | (This content is a preprint and has not been peer-reviewed.) | AptaGen |
DNA | ATACCAGCTTATTCAATTCAGGGCGGTATGAGGCTCGATCAAGGTCGGAGCGAGAATTTTTTCGCGGAGTCGGCTGGATCAGATAGTAAGTGCAATCT | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O | 8.29243 | 1 | Selection Buffer: 100 mM NaCL, 20 mM Tris-HCl pH 7.6, 2 mM MgCl | Stoltenburg R, Nikolaus N, Strehlitz B.(2012) Capture-SELEX: Selection of DNA Aptamers for Aminoglycoside Antibiotics. | AptaGen |
RNA | GGGAAUGGAUCCACAUCUACGAAUUCACCGCGGGGUUGCGGACCGGGAGCUCCAGCUUCACUGCAGACUUGACGAAGCUU | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O | 6.522879 | 1 | Binding Buffer (500 mM NaCl, 50 mM Tris (pH 7.6)) | Lato et al. "In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution." Chemistry & Biology, 2(1995): 291-303. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O | 7.277366 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O | 7.155523 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
DNA | GGGATCGAAACGTAGCGCCTTCGATCCC | NC(N)=NCCCC(N)C(=O)O | 8.60206 | 1 | Buffer for CD binding assay: 10 mM sodium phosphate buffer (pH 7.5) and 100 mM NaCl. | K Harada and A Frankel. (1995) Identification of two novel arginine binding DNAs. | AptaGen |
DNA | GACCAGGGCAAACGGTAGGGAGTGGTC | NC(N)=NCCCC(N)C(=O)O | 2.60206 | 0 | Buffer for CD binding assay: 10 mM sodium phosphate buffer (pH 7.5) and 100 mM NaCl. | K Harada and A Frankel. (1995) Identification of two novel arginine binding DNAs. | AptaGen |
RNA | GGAGCUCAGCCUUCACUGCAUGAUAAACCGAUGCUGGGCGAUUCUCCUGAAGUAGGGGAAGAGUUGUCAUGUAUGGGGGCACCACGGUCGGAUCCUG | NC(N)=NCCCC(N)C(=O)O | 6.481486 | 1 | Binding buffer: 250 mM NaCl, 50 mM Trisƒ??HCl (pH 7.6), 5 mM MgCl | Geiger, Albert, | AptaGen |
RNA | GACGAGAAGGAGCGCUGGUUCUACUAGCAGGUAGGUCACUCGUC | NC(N)=NCCCC(N)C(=O)O | 7.221849 | 1 | Binding Buffer (250 mM NaCl, 50 mM Tris-HCl (pH=8.3), 5 mM MgCl2) | Famulok, M., " Molecular Recognition of Amino Acids by RNA-Aptamers: An L-Citrulline Binding RNA Motif and its Evolution into an L-Arginine Binder." Journal of the American Chemical Society, 116 (1994): 1698-1706. | AptaGen |
RNA | GACGAGAAGGAGUGCUGGUUAUACUAGCGGUUAGGUCACUCGUC | NC(=O)NCCCC(N)C(=O)O | 4.167491 | 1 | Binding Buffer (250 mM NaCl, 50 mM Tris-HCl (pH=8.3), 5 mM MgCl2) | Famulok, M., " Molecular Recognition of Amino Acids by RNA-Aptamers: An L-Citrulline Binding RNA Motif and its Evolution into an L-Arginine Binder." Journal of the American Chemical Society, 116 (1994): 1698-1706. | AptaGen |
RNA | GGCAUCGGAAAGUGGGUUGAUGUAAGUAACAGGCGAUGCC | NC(Cc1cnc[nH]1)C(=O)O | 4.920819 | 1 | Selection Buffer (50 mM Hepes (pH 7.0), 250 mM NaCl, 5 mM each CaCl2 and MgCl2, and 1 mM glycine) | Majerfeld, et al. "RNA Affnity for Molecular L-Histidine; Genetic Code Origins." Journal of Molecular Evolution, 61 (2005): 226-235. | AptaGen |
RNA | GGUCUUACGUCGUUCGCGACUAUUGGGAGACC | CCC(C)C(N)C(=O)O | 3.69897 | 0 | Selection Buffer (10 mM HEPES (pH 7.0), 300 mM NaCl, and 7.5 mM MgCl2 (buffer B) and 0.1 mM each of ZnCl2, CaCl2, and MnCl2 and 0.01 mM CuCl) Reaction Buffer (50 mM sodium borate (pH 8.0), 42 mM KCl, 7.5 mM MgCl2, and 0.4 mM ZnCl2) | Majerfeld and Yarus. "Isoleucine:RNA sites with associated coding sequence." RNA, 4 (1998): 471-478. | AptaGen |
RNA | GGGAGCUCAGAAUAAACGCUCAAAUCCGUGGACAGGGCGUAAGCGCCUUCGACAUGAGACACGGAUCCUGCGACGAAUUCAGC | CC(C)C(N)C(=O)O | 1.920819 | 0 | Selection Buffer (25 mM HEPES, 200 mM NaCl, 6 mM MgCl2, 1 mM EDTA (pH 7.3)) | Majerfeld and Yarus. "An RNA Pocket for an Aliphatic Hyrdrophobe." Nature Structural Biology, 1(1994): 287-292. | AptaGen |
DNA | GGGACGACCGTCCGAGTTTTAGGAGTGGTTGCATTGCGCTGGGAAGAGGTCGTCCC | CNC(C)Cc1ccccc1 | 5.309804 | 1 | 1X PBS (pH 7.4, 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4) with 1 mM MgCl2 at room temperature | Determining the Precision of High-Throughput Sequencing and Its Influence on Aptamer Selection | AptaGen |
DNA | TTCAAATCTTGGTACGTTCTGCCTTTTCTTATTTTGCTTTGGGTTACCTAGTCTAGATTTGAA | CNC(C)Cc1ccccc1 | 5.60206 | 1 | 0.5× PBS, 5 mM MgCl2, 0.005% Triton X-100 at room temperature | Examining the Relationship between Aptamer Complexity and Molecular Discrimination of a Low-Epitope Target | AptaGen |
RNA | GGGAGACAAGAAUAAACGCUCAACUGCGAUCAGGGGUAAAUUUCCGCGCAGGCUCCACGCCGCUUCGACAGGAGGCUCACAACAGGC | Nc1ccc(Cc2ccc(N)cc2)cc1 | 6.346787 | 1 | Binding buffer: 250 mM NaCl, 50 mM Trisƒ??HCl, 5 mM MgCl | Brockstedt, U., | AptaGen |
DNA | TTCAAATCTGAGCAGCCTAGTTACTGACGGGTTTATAGTACTCGCATTGAGTCTAGATTTGAA | CNC(C)Cc1ccccc1 | 5.482804 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | TTCAAATCTGAGCAGCCTAGTTACTGACGGGTTTATAGTACTCGTATTGAGTCTAGATTTGAA | CNC(C)Cc1ccccc1 | 5.610834 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | TTCAAATCTGGTGCCCTTTCGCAGTCGGTTGGTAATGAGACCACTTTAGAGTCTAGATTTGAA | CNC(C)Cc1ccccc1 | 5.352617 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | TTCAAATCTGAGCAGCCTAGTTACTGACGGGTTTATAGTACTCGCATCGAGTCTAGATTTGAA | CNC(C)Cc1ccccc1 | 5.679854 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
RNA | GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC | [Mn+2] | 3 | 0 | Standard Reaction Conditions: 50 mM Tris-HCl, pH 7.5, 20 mM MgCl | Seetharaman et al. "Immobolized RNA switches for the analysis of complex chemical and biological mixtures." Nature Biotechnology, 19(2001): 336-341. | AptaGen |
RNA | GGAACCCAACUAGGCGUUUGAGGGGAUUCGGCCACGGUAACAACCCCUC | NC(=O)c1ccc[n+](C2OC(COP(=O)([O-])OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2O)c1 | 8.60206 | 1 | Selection Buffer (20 mM HEPES (pH 7.5), 300 mM KC1, and 5 mM MgC12) at room temperature | Lauhon and Szostak. "RNA Aptamers That Bind Flavin and Nicotinamide Redox Cofactors." Journal of the American Chemical Society, 117(1994): 1246-1257. | AptaGen |
RNA | GGAACCCAACUAGGCGUUUGAGGGGAUUCGGCCACGGUAACAACCCCUC | NC(=O)C1=CN(C2OC(COP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2O)C=CC1 | 7.431798 | 1 | Selection Buffer (20 mM HEPES (pH 7.5), 300 mM KC1, and 5 mM MgC12) at room temperature. | Lauhon and Szostak. "RNA Aptamers That Bind Flavin and Nicotinamide Redox Cofactors." Journal of the American Chemical Society, 117(1994): 1246-1257. | AptaGen |
DNA | CTTACGACACAGGGCGTGGAGTGGCTGGGCTTCAAGGGGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 6.910095 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | ACGACAGGTTCTGAGGAATCAACGTCGGTGTAGTTGTCGT | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 6.262807 | 1 | Selection buffer: 20 mM Tris-HCl (pH 7.4 at 25 °C), 140 mM NaCl, 4 mM KCl, 5 mM MgCl2 | Alkhamis O., Canoura J., Wu Y., Emmons N.A., Wang Y. et al. (2024). High-Affinity Aptamers for In Vitro and In Vivo Cocaine Sensing. Journal of the American Chemical Society, (146)5, 3230-3240. https://doi.org/10.1021/jacs.3c11350 | AptaGen |
DNA | CTTACGACGGTGGGGGGTTGGTAGGGGAGGAGCGCATCGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 5.958607 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | CTTACGACAGTAACGGTGGGTATATGGGATTTATGTTCGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 6.549751 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | CTTACGACTTGTTCTGAGGGTCAACGGTGGTGTAGTTAGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 7.657577 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | CTTACGACTAGTTCCGGGTAGGGGTAGGCGTGGTTGTGGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 7.154902 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | CTTACGACGACCTAGTGGGGGTAGTTATAGTTGGGTGAGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 5.993106 | 1 | null | null | AptaGen |
DNA | CTTACGACACAGGGCGTGGAGGAGCTGGGCTATTAGGGGTCGTAAG | COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | 5.924453 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O | 7.394695 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O | 7.431798 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC | [Ni+2] | 4 | 0 | Standard Reaction Conditions: 50 mM Tris-HCl, pH 7.5, 20 mM MgCl | Seetharaman et al. "Immobolized RNA switches for the analysis of complex chemical and biological mixtures." Nature Biotechnology, 19(2001): 336-341. | AptaGen |
RNA | GGGAGAGGAUACUACACGUGGAAAAACCAACAAAUUGGGAAAAAUGUUAAGGGUCCACUUCAUGCCAUUGCAUGUAGCAGAAGCUUCCG | [Ni] | 6.09691 | 1 | Ni-NTA resin (200 uL) equilibrated with a buffer (50 mM NaCl, 7 mM MgCl2, 50 mM Tris-HCl (pH 7.5) was heated at 75C for 3 min and then slowly cool to RT. The Sample was loaded on the Ni-NTA matrix for 5 min under gentle agitation. | Hoffman, H., et al. "Ni2+-binding RNA motifs with an asymmetric purine-rich internal loop and a G-A base pair." RNA Journal, 3 (1997): 1289-1300. | AptaGen |
DNA | GGGAGGACGAAGCGGAACCGGGTGTGGGTGCCTTGATCCAGGGAGTCTCAGAAGACACGCCCGACA | CC1Cc2c(Cl)cc(C(=O)NC(Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 | 7.017729 | 1 | Binding Buffer: PBS 1X, 1 mM MgCl | L Barthelmebs et al. Enzyme-linked aptamer assays (ELAAs), based on a competition format for a rapid and sensitive detection of ochratoxin A in wine. | AptaGen |
DNA | GGTCACCAACAACAGGGAGCGCTACGCGAAGGGTCAATGTGACGTCATGCGGATGTGTGG | C=C1C(O)C2OC3(CCC(C=CC(C)C4CC(C)=CC5(OC(CC(C)(O)C(=O)O)CCC5O)O4)O3)CCC2OC1C(O)CC(C)C1OC2(CCCCO2)CCC1C | 7.113509 | 1 | 50 mM Tris, pH 7.5, 150 mM NaCl, 2 mM MgCl2 | Eissa, S., Ng, A., Siaj, M., Tavares, A., and Zourob, M. "Selection and Identification of DNA Aptamers against Okadaic Acid for Biosensing Application." Analytical Chemistry 85.24 (2013): 11794-801. | AptaGen |
DNA | GGGACGACATCGTAGGGGCACACGCTTAACGGGCTGATGTCGTCCC | COc1ccc2c3c1OC1C(=O)CCC4(O)C(C2)N(C)CCC314 | 5.847712 | 1 | null | Obtin Alkhamis, Caleb Byrd, Juan Canoura, Adara Bacon, Ransom Hill, Yi Xiao, Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity, Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf219, https://doi.org/10.1093/nar/gkaf219 | AptaGen |
DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | CNC(=O)CSP(=O)(OC)OC | 5.60206 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | CNC(=O)CSP(=O)(OC)OC | 5.69897 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CO)C(O)C(O)C3N)C2O)C(N)C(O)C1O | 7.669586 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CO)C(O)C(O)C3N)C2O)C(N)C(O)C1O | 7.703335 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
DNA | ACTCACTATGGAAGAGATGGCGACATCTCTTCTCCGAGCCGGTCGAAATAGTGAGT | [Pb] | 8.39794 | 1 | Buffer A (50 mM HEPES, 500 mM NaCl, 20 uM EDTA (pH 7.0) | Lu et al. "New highly sensitive and selective catalytic DNA biosensors for metal ions." Biosensors and Bioelectronics, 18(2003): 529-540. | AptaGen |
DNA | CTCTCGGGACGACGGACGCTAATCTTACAAGGGCGTAGTGTATGTCGTCCC | NC(Cc1ccccc1)C(=O)O | 8.49485 | 1 | 100 μM concentration of monomeric Cp*Rh(III) | Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058 | AptaGen |
RNA | AUUGGAUCGGUAGUAUUUAGGGUGAGACACUUCAUGCCUUUGUUGCAGGCUGGGGUGAAGGCGCUACAUGGCGUCUGAAA | NC(Cc1ccccc1)C(=O)O | 4.468521 | 1 | Selection Buffer (50 mM Hepes (pH 7.0), 0.3 M NaCl, 5 mM CaCl2, and 5 mM MgCl2) | Illangasekare and Marus. "Phenylalanine-Binding RNAs and Genetic Code Evolution." Journal of Molecular Evolution, 54(2002): 298-311. | AptaGen |
DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | CCOP(=S)(OCC)SCSCC | 5.954677 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | CCOP(=S)(OCC)SCSCC | 5.844664 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC | CCCSP(=O)(OCC)Oc1ccc(Br)cc1Cl | 6 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG | CCCSP(=O)(OCC)Oc1ccc(Br)cc1Cl | 5.90309 | 1 | Selection buffer used in binding affinity assays: 300mM NaCl, 50 mM KCl, 10 mM MgCl | Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. | AptaGen |
DNA | GCACACCGATGGCGGTCCTGTTTAGGGGGTGTGC | Nc1nc(N)nc(N)n1 | 9.022276 | 1 | Cyanuric acid, Ammeline, Ammelide. | Gu, Chunmei et al. “Label-free fluorescence detection of melamine with a truncated aptamer.” The Analyst vol. 141,14 (2016): 4511-7. doi:10.1039/c6an00537c | AptaGen |
DNA | CGACTGGTAGGCAGATAGGGGAAGCTGATTCGATGCGTGGGTCG | NCCc1c[nH]c2ccc(O)cc12 | 6.101824 | 1 | 25°C in 1X PBS buffer with 2 mM MgCl2 | Shuyuan Zhang, Gege Song, Zhan Yang, Kai Kang, Xiaoqing Liu, A label-free fluorescence aptamer sensor for point-of-care serotonin detection, Talanta, Volume 277, | AptaGen |
DNA | GACAGGCAGGACACCGTAACGTTAGACGCTGGACCGCGTGTGATCGGGTCAGCTGCAATTCTGCTACCTCCCTCCTCTTC | Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 | 6.775208 | 1 | 20 mM Tris-HCl, 100 mM NaCl, 2 mM MgCl2, 5 mM KCl, 1 mM | Kou, Q., Wu, P., Sun, Q., Li, C., Zhang, L., Shi, H., … Le, T. (2020). Selection and truncation of aptamers for ultrasensitive detection of sulfamethazine using a fluorescent biosensor based on graphene oxide. Analytical and Bioanalytical Chemistry. doi:10.1007/s00216-020-03044-2 | AptaGen |
DNA | TAGGGAATTCGTCGACGGATCCGGGGTCTGGTGTTCTGCTTTGTTCTGTCGGGTCGTCTGCAGGTCGACGCATGCGCCG | CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O | 6.700929 | 1 | Binding buffer used to wash samples was as follows: 20 mM Tris–HCl containing 100 mM NaCl, 2 mM | Zhou N, Wang J, Zhang J, Li C, Tian Y, Wang J. Selection and identification of streptomycin-specific single-stranded DNA aptamers and the application in the detection of streptomycin in honey. Talanta. 2013 Apr 15;108:109-16. doi: 10.1016/j.talanta.2013.01.064. Epub 2013 Feb 28. PMID: 23601877. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O | 7.301899 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O | 7.703335 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
DNA | CCGGCCAAGGGTGGGAGGGAGGGGGCCGG | CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 | 6.721246 | 1 | Selection Buffer: 0.1 M KCl, 5 mM MgCl | Wilson C, Szostak J. (1998) Isolation of a fluorophore-specific DNA aptamer with redox activity. | AptaGen |
DNA | CGTACGGAATTCGCTAGCCCCCCGGCAGGCCACGGCTTGGGTTGGTCCCACTGCGCGTGGATCCGAGCTCCACGTG | CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(C)(O)C3CC12 | 7.196543 | 1 | Briefly, the target chemical-coated magnetic | Niazi, J. H., Lee, S. J., & Gu, M. B. (2008). Single-stranded DNA aptamers specific for antibiotics tetracyclines. Bioorganic & medicinal chemistry, 16(15), 7245–7253. https://doi.org/10.1016/j.bmc.2008.06.033 | AptaGen |
RNA | GGCCUAAAACAUACCAGAUUUCGAUCUGGAGAGGUGAAGAAUUCGACCACCUAGGCCGGU | CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(C)(O)C3CC12 | 6 | 1 | Equilibration Buffer: 10 mM Trisƒ??HCl (pH 7.6), 5 mM MgCl | Berens C, Thain, A, Schroeder R. (2001) A tetracycline-binding RNA aptamer. | AptaGen |
DNA | CTTACGACCCAGGGGGGTGGACAGGCGGGGGTTAGGGGGGTCGTAAG | CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CCC(C)=CC21 | 7.39794 | 1 | 20 mM Tris-HCl, | Yu, H., Luo, Y., Alkhamis, O., Canoura, J., Yu, B., & Xiao, Y. (2021). Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids. Analytical chemistry, 93(6), 3172–3180. https://doi.org/10.1021/acs.analchem.0c04592 | AptaGen |
RNA | GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGUCUGGAUACCAUGCAUGAUGCACCUUGGCAGUCUUACGAAACGGUAGCGAGAGCUC | Cn1c(=O)c2[nH]cnc2n(C)c1=O | null | 1 | Standard Reaction Conditions: 50 mM Tris-HCl, pH 7.5, 20 mM MgCl | Seetharaman et al. "Immobilized RNA switches for the analysis of complex chemical and biological mixture." Nature Biotechnology, 19(2001):336-341. | AptaGen |
RNA | GGGCGACCCUGAUGAGCCUUAUACCAGCCGAAAGGCCCUUGGCAGACGUCGAAACGGUGAAAGCCGUAGGUUGCCC | Cn1c(=O)c2[nH]cnc2n(C)c1=O | null | 1 | Reaction buffer [50 mM Tris.HCl (pH 7.5) and 20 mM MgCl2] for 20 hr | Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" | AptaGen |
RNA | GGGCGACCCUGAUGAGAUGAUACCAGCCGAAAGGCCCUUGGCAGCUCUCGAAACGGUGAAAGCCGUAGGUUGCCC | Cn1c(=O)c2[nH]cnc2n(C)c1=O | null | 1 | Reaction buffer [50 mM Tris.HCl (pH 7.5) and 20 mM MgCl2] for 20 hr | Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" | AptaGen |
RNA | AGUGAUACCAGCAUCGUCUUGAUGCCCUUGGCAGCACU | Cn1c(=O)c2[nH]cnc2n(C)c1=O | 7 | 1 | Buffer A (100 mM Hepes (pH 7.3), 5 mM MgCI2, and 0.5 M NaCI) | Jenison | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUAGGCCCGACAUUCCCCUAAAAAAGCUUGUUCUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O | 7.716699 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
RNA | GGGAGAAGGCGGCGCGUAGGCGAGCUUUACCAGUUUUAUUUGUUUUAUUGUUAUAUGCUUAUUCGUGGACGAUGCGCAC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O | 7.605548 | 1 | Binding Buffer: PBS with 10% (v/v) methanol | N. Derbyshire et al. Toggled RNA aptamers against aminoglycosides allowing facile detection of antibiotics using gold nanoparticle assays. | AptaGen |
DNA | CTCTCGGGACGACCGCGGTAGTCTTAACCTAAAGCGGTGTCAGGTCGTCCC | NC(Cc1c[nH]c2ccccc12)C(=O)O | 5.920819 | 1 | 100 μM concentration of monomeric Cp*Rh(III) | Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058 | AptaGen |
DNA | CTCTCGGGACGACGGCCCGATCTCAGAGTAGTCGTCCC | NC(Cc1ccc(O)cc1)C(=O)O | 8.537602 | 1 | 100 μM concentration of monomeric Cp*Rh(III) | Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058 | AptaGen |
DNA | ACGACAGGGCAAGAGGTTTTACTTACCTAAGGAATGTCGT | O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1 | 5.39794 | 1 | Binding Buffer (20mM Tris, 150mM NaCl, 10 mM MgCl2, 10 mM KCl, pH 8.3 | Liu, Y., & Liu, J. (2023). Salt-Toggled Capture Selection of Uric Acid Binding Aptamers. Chembiochem : a European journal of chemical biology, 24(2), e202200564. https://doi.org/10.1002/cbic.202200564 | AptaGen |
DNA | CTTACGACTGTGGTCGGGTGGTGGGCCTCTAGAGGGGTGTCGTAAG | CC1(C)C(C(=O)c2cn(CCCCCF)c3ccccc23)C1(C)C | 6.508638 | 1 | 20 mM Tris-HCl, | Yu, H., Luo, Y., Alkhamis, O., Canoura, J., Yu, B., & Xiao, Y. (2021). Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids. Analytical chemistry, 93(6), 3172–3180. https://doi.org/10.1021/acs.analchem.0c04592 | AptaGen |
RNA | GGCACGUGUAUUACCCUAGUGGUCGACGUGCC | O=c1[nH]c(=O)c2[nH]cnc2[nH]1 | 8.481486 | 1 | Binding Buffer (20 mM Trisƒ??HCl (pH 7.5), 0.3 M NaCl and 5 mM MgCl2) | Kiga, D., et al. "An RNA aptamer to the xanthine/guanine base with a distinctive mode of purine recognition." Nucleic Acids Research, 26 (1998): 1755-1760. | AptaGen |
RNA | GGGAGAGGAUACUACUGUCAUACGUUAGGCUGUAGGCGAGGUGAAAUGAGCGGUAAUAGCCUCAGCGUAGCAUAUGCAUGAAUUCGAAGCUUCGC | [Zn] | 2.920819 | 0 | Buffer A (0.4 M NaCl, 20 mM HEPES-Na (pH 7.0), and 1 mM MgCl2) | Ciesiolka et al., "Selection of an RNA domain that binds Zn2+." Journal of RNA, 1(1995): 538-550. | AptaGen |
RNA | GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGAAAGCCAAAGCCGUAGCGCAGAUGAUCUCGCCAUCAGUACCGAAACGGUAGCGAGAGCUC | [Zn+2] | 4 | 0 | Standard Reaction Conditions: 50 mM Tris-HCl, pH 7.5, 20 mM MgCl | Seetharaman et al. "Immobolized RNA switches for the analysis of complex chemical and biological mixtures." Nature Biotechnology, 19(2001): 336-341. | AptaGen |
RNA | GACGAGAAGGAGCGCUGGUUCUACUAGCAGGUAGGUCACUCGUC | NC(N)=NCCCC(N)C(=O)O | 4.251812 | 1 | 250 mM NaCl; 50 mM Tris-HCl, pH = 7.6; 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/10786843/ | UTexas |
RNA | GGAGCUCAGCCUUCACUGCAUGAUAAACCGAUGCUGGGCGAUUCUCCUGAAGUAGGGGAAGAGUUGUCAUGUAUGGGGGCACCACGGUCGGAUCCUG | NC(N)=NCCCC(N)C(=O)O | 5.480303 | 1 | 250 mM NaCl, 50 mM Tris–HCl pH 7.6, 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/8604334/ | UTexas |
RNA | GGGCGACCCCAGUGCAUUGCGAAGAAACUGUGCGACUUCGGUCGCAGCAAACGUCGGCGCCGUAGGUUGCCC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | null | 1 | 50 mM Tris-HCl, pH 7.5, at 23 °C, and 20 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9257650/ | UTexas |
RNA | UUUGUAGGCGACCUACCACUCUCGUGGCCCAGUGCAUUGCUGCGACCGAAGUCGCCAGUUUCUUCCCAAAUGUCGUCGCCAUCUCUUCC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | null | 1 | 50 mM Tris-HCl, pH 7.5, at 23 °C, and 20 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9257650/ | UTexas |
RNA | GGCACGUGUAUUACCCUAGUGGUCGACGUGCC | O=c1[nH]c(=O)c2[nH]cnc2[nH]1 | 5.481486 | 1 | 20 mM Tris–HCl, pH 7.5, 0.3 M NaCl and 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9512549/ | UTexas |
RNA | GGCACGUGUAUUACCCUAGUGGUCGACGUGCC | Nc1nc2nc[nH]c2c(=O)[nH]1 | 5.886057 | 1 | 20 mM Tris–HCl, pH 7.5, 0.3 M NaCl and 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9512549/ | UTexas |
RNA | GGACGGCACCACGGUCGGAUCCGUGAGUUGUGACAAUUUAGCGGGUGGUAUUAGAGCCUACUGCCACAGCAAUAGGAUCGAUACAGAUCU | O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21 | null | 1 | 100 mM KCl, 5 mM MgCl2, 10 mM Na-HEPES, pH 7.4 | https://pubmed.ncbi.nlm.nih.gov/9889155/ | UTexas |
DNA | TAGCGGGTGTGGTGGGTGGGGGAGGCATGGTTTTTGGTAA | OCC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O | 6 | 1 | 20 mM Tris, pH 7.5/100 mM NaCl/5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9576904/ | UTexas |
DNA | GTCAAGGTGGGTGGGTGGGGTTGGTTGTTGTTTTGA | OCC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O | 6 | 1 | 20 mM Tris, pH 7.5/100 mM NaCl/5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/9576904/ | UTexas |
RNA | GGCUUAGUAUAGCGAGGUUUAGCUACACUCGUGCUGAGCC | NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O | 8.288193 | 1 | Not reported | https://pubmed.ncbi.nlm.nih.gov/9425088/ | UTexas |
RNA | GGAUCGCAUUUGGACUUCUGCCCAGGGUGGCACCACGGUCGGAUCC | CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O | null | 1 | 5 mM MgCl2, 50 mM Tris-HCl, pH 7.6, 250 mM NaCl | https://pubmed.ncbi.nlm.nih.gov/9436913/ | UTexas |
RNA | AUCACCUCAAGGAAAACGCUUCAGAAAGGGACUUAGGUGAU | CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O | null | 1 | 5 mM MgCl2, 50 mM Tris-HCl, pH 7.6, 250 mM NaCl | https://pubmed.ncbi.nlm.nih.gov/9436913/ | UTexas |
RNA | GGAAGGCACGACGAAGCAAGCAGGCAACGAACACAGAAGACCGGGGGAACUACCGCGCGUGCCAGACCCAACCAGCCAGAGACC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | 3.651695 | 0 | 300 mM NaCl, 20 mM Tris-Cl, pH 7.4, 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/11101810/ | UTexas |
RNA | GGAAGGCACGACGAAGCAAGCAGGCAACGAACACAGAAGACCGGGGGAACUACCGCGCGCGCCAGACCCAACCAGCCAGAGACC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | 3.782516 | 0 | 300 mM NaCl, 20 mM Tris-Cl, pH 7.4, 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/11101810/ | UTexas |
RNA | GGGCGCGACGAAGCAAGCAGGCAACGAACACAGAAGACCGGGGGAACUACCGCGCGCGCCC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | 6.756962 | 1 | 300 mM NaCl, 20 mM Tris-Cl, pH 7.4, 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/11101810/ | UTexas |
RNA | GGAAGGCACGACCGCGCAAGAUACCGCCCGACAGCGGAAGGAGGGGCAUGCGGUCCAGGGCUGAGACCCAACCAGCCAGAGACC | Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O | null | 1 | 300 mM NaCl, 20 mM Tris-Cl, pH 7.4, 5 mM MgCl2 | https://pubmed.ncbi.nlm.nih.gov/11101810/ | UTexas |
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