Title stringlengths 0 905 | Abstract stringlengths 0 11.3k | Container_Title stringlengths 0 126 | Subject listlengths 1 13 |
|---|---|---|---|
Long noncoding RNAs: novel links to inflammatory bowel disease? | [
"Physiology (medical)",
"Gastroenterology",
"Hepatology",
"Physiology"
] | ||
Forthcoming meetings | [
"Histology",
"Pathology and Forensic Medicine"
] | ||
Labeling of a cysteine in the cardiotonic glycoside binding site by the steroid derivative HDMA | [
"Cell Biology",
"Genetics",
"Molecular Biology",
"Biochemistry",
"Structural Biology",
"Biophysics"
] | ||
Net Power Optimization Based on Extremum Search and Model-free Adaptive Control of PEMFC Power Generation System for High Altitude | [
"Electrical and Electronic Engineering",
"Energy Engineering and Power Technology",
"Transportation",
"Automotive Engineering"
] | ||
Guard Always Your Honor: “Ehrengard,” Karen Blixen’s Last Tale | Scandinavian Studies | [
"Literature and Literary Theory",
"Linguistics and Language",
"Language and Linguistics"
] | |
Clinical correlations of hypocomplementaemia in systemic sclerosis: an analysis of the EULAR Scleroderma Trial and Research group (EUSTAR) database | [
"Immunology",
"Immunology and Allergy",
"Rheumatology"
] | ||
A synthetic hexapeptide (Argireline) with antiwrinkle activity | [
"Colloid and Surface Chemistry",
"Dermatology",
"Drug Discovery",
"Pharmaceutical Science",
"Aging",
"Chemistry (miscellaneous)"
] | ||
Deformations of the Sayano-Shushenskoe dam ? Measurement results and problems | [
"Energy Engineering and Power Technology",
"Geotechnical Engineering and Engineering Geology",
"Ocean Engineering",
"Water Science and Technology"
] | ||
A 42-Kilodalton Annexin-Like Protein Is Associated with Plant Vacuoles | [
"Plant Science",
"Genetics",
"Physiology"
] | ||
Tribological Characteristics of Human Vascular Smooth Muscle Cells: The Implication of Disease State on Friction | Biotribology | [
"Surfaces, Coatings and Films",
"Biomaterials"
] | |
Quantum eigenstates of curved nanowire structures | [
"Electrical and Electronic Engineering",
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | ||
Making sense of the square: Facing the touristification of public space through playful protest in Barcelona | Drawing from assemblage thinking, this article explores the complexity of urban tourism conflicts. The case study of a playful urban intervention in Barcelona exhibits the connections that link place-based activism, local identity construction and sense of place in relation to the tourism development. The productive case study, called Fem Plaça (Let’s make the square), highlights the more proactive rather than merely reactive role of inhabitants. Moreover, it allows for a better understanding of protest as a series of relational, processual practices of empowerment, overcoming the efficiency rhetoric that values a process only for its final success. Finally, this study strives to expand the tourist analysis to the performance and performativity of the local people’s disaffection in urban contexts to ensure a broader comprehensiveness in the tourist academic field. | [
"Tourism, Leisure and Hospitality Management"
] | |
Dielectric properties of polymer-dispersed antiferroelectric liquid crystals influenced by flexoelectric polarization | [
"Materials Chemistry",
"Polymers and Plastics",
"Condensed Matter Physics"
] | ||
Demografía y sociedad en Castilla la Nueva Durante el Antiguo Régimen: La villa de Los Molinos, 1620-1730 | [
"Sociology and Political Science"
] | ||
Towards meaningful participation in humanitarian studies: co-researching with persons with disabilities in Central Sulawesi | PurposeThis paper presents the experience of co-researching with persons with disabilities in Water, Sanitation and Hygiene (WASH) humanitarian programming using participatory methods that enable empowerment.Design/methodology/approachThis paper focuses on methods that ensure the active participation of persons with disabilities as co-researchers. These methods include building the capacity of persons with disabilities on the research topic and instruments, pre-interview role-plays, field pilot testing, post-data collection debriefing and reflective learning through writing learning diaries.FindingsThis research shows that persons with disabilities have the drive and capacity to contribute to research. Methods such as continuous engagement, capacity building and feedback mechanisms are essential for their participation and influence in the research production process. These methods can provide empowering experiences for persons with disabilities. However, they are often time-consuming and can be convoluted.Originality/valueResearch conducted with persons with disabilities in disaster and humanitarian studies is still scarce. Consequently, resources on inclusive and participatory methodology involving persons with disabilities are minimal. Therefore, this article contributes to addressing this knowledge gap. | [
"Public Health, Environmental and Occupational Health",
"Management, Monitoring, Policy and Law",
"Health (social science)"
] | |
Implication of the Cystic Fibrosis Transmembrane Conductance Regulator Gene in Infertile Family Members of Indian CF Patients | [
"Genetics",
"Molecular Biology",
"Ecology, Evolution, Behavior and Systematics",
"Biochemistry"
] | ||
Zeichen und Wunder | [
"Automotive Engineering"
] | ||
The color specification of scottish tartans | [
"Human Factors and Ergonomics"
] | ||
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening | [
"Health, Toxicology and Mutagenesis",
"Clinical Biochemistry",
"Biochemistry"
] | ||
Sudden Heart Rate Reduction Upon Optogenetic Release of Acetylcholine From Cardiac Parasympathetic Neurons in Perfused Hearts | [
"Physiology (medical)",
"Physiology"
] | ||
Ligands for Molecular Imaging: The Synthesis of Bis(thiosemicarbazone) Ligands | [
"Catalysis",
"Organic Chemistry"
] | ||
Problems of Diagnosis and Treatment in the Dandy-Walker Syndrome | 10 children with Dandy-Walker syndrome are presented to discuss their clinical assessment and therapy. The presence on physical examination of a large posterior fossa was the most reliable clinical finding and was diagnostic in 9 out of the 10 patients. The different diagnostic confirmatory studies are discussed. The most satisfactory treatment in this series was the combination of a shunt from the lateral ventricle and the posterior fossa to the peritoneum. | [
"Neurology (clinical)",
"Surgery",
"Pediatrics, Perinatology and Child Health"
] | |
Solar irradiance reference spectra for two solar active levels | Advances in Space Research | [
"Space and Planetary Science",
"Aerospace Engineering",
"Atmospheric Science",
"Geophysics",
"Astronomy and Astrophysics"
] | |
The Impact of Social Exclusion on “Reading the Mind in the Eyes” Performance in Relation to Borderline Personality Disorder Features | In this study we used the Reading the Mind in the Eyes Test (RMET) to explore facial emotion recognition in borderline personality disorder (BPD). We also used Cyberball, a computerized task designed to mimic social ostracism, to examine the response of BPD-feature participants to social exclusion. Seventeen individuals with BPD features were compared to 16 healthy controls on RMET performance pre- and post-exclusion via Cyberball. Our results revealed a significant interaction between BPD-feature status and RMET performance in relation to neutral stimuli following a social exclusion experience. BPD participants' ability to correctly identify neutral faces significantly decreased following exclusion. This finding suggests that once an individual with BPD features experiences a social exclusion event, his or her objectivity decreases and affective valence is ascribed to stimuli previously perceived as neutral. Our results may help to explain, in part, the social instability seen in BPD. | [
"Psychiatry and Mental Health",
"Clinical Psychology"
] | |
The French socialists | [
"Political Science and International Relations"
] | ||
Nancy L. Green and Francois Weil, editors.Citizenship and Those Who Leave: The Politics of Emigration and Expatriation.:Citizenship and Those Who Leave: The Politics of Emigration and Expatriation.(Studies of World Migrations.) | [
"Museology",
"Archeology",
"History"
] | ||
Selecting and justifying quantitative analysis techniques in single-case research through a user-friendly open-source tool | Certain quantification techniques may be more appropriate than others for single-case design analysis depending on the research questions, the data or graph characteristics, and other desired features. The purpose of this study was to introduce a newly developed and empirically validated user-friendly tool to assist researchers in choosing and justifying single-case design quantification techniques. A total of sixteen different quantification techniques and nine facets (research questions, data or graph characteristics, or desired features) that may affect the appropriateness of a single-case experimental design quantification technique were identified to be included in the tool. The resulting tool provides a ranking of recommended quantification techniques, from most to least appropriate, depending on the user input. A pretest and posttest design was utilized to test the effectiveness of the tool amongst 25 participants. The findings revealed that those who use single-case designs may need support in choosing and justifying their use of quantification techniques. Those who utilize single-case designs should use the developed tool (and other tools) to assist with their analyses. The open-source tool can be downloaded from osf.io/7usbj/. | [
"Education"
] | |
A method for calculating surface stress and surface elastic constants by molecular dynamics: application to the surface of crystal and amorphous silicon | [
"Materials Chemistry",
"Metals and Alloys",
"Surfaces, Coatings and Films",
"Surfaces and Interfaces",
"Electronic, Optical and Magnetic Materials"
] | ||
Diseases of the nose, throat and ear. Edited by Chevalier Jackson, M.D., Sc.D., LL.D., L.H.D., F.A.C.S., and Chevalier L. Jackson, M.D., M.Sc., F.A.C.S. Second edition. 10 × 6¾ in. Pp. 886 + xviii, with 110 illustrations. 1959. Philadelphia and London: W. B. Saunders Co. 140s | [
"Surgery"
] | ||
Fesser, Gerd, Von der Napoleonzeit zum Bismarckreich. Streiflichter zur deutschen Geschichte im 19. Jahrhundert | [
"Law",
"History"
] | ||
Relationship between Global Carbon Cycle and Climate Change during Cenozoic: Is CO2 the Principal Cause of Long-term Climate Change? | Journal of Geography (Chigaku Zasshi) | [
"Earth-Surface Processes",
"Geology",
"Geophysics",
"Geography, Planning and Development",
"Global and Planetary Change"
] | |
Network analysis in CEA, ecosystem services assessment and green space planning | [
"Management, Monitoring, Policy and Law",
"Geography, Planning and Development"
] | ||
Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors | [
"Radiology, Nuclear Medicine and Imaging",
"Oncology"
] | ||
Behaviour of cattle using an automated feeding system | [
"Animal Science and Zoology"
] | ||
Impaired Male Sexual Development in Perinatal Sprague-Dawley and Long-Evans Hooded Rats Exposed in Utero and Lactationally to p,p′-DDE | Toxicological Sciences | [
"Toxicology"
] | |
CORRIGENDUM | Journal of Fluid Mechanics | [
"Mechanical Engineering",
"Mechanics of Materials",
"Condensed Matter Physics"
] | |
Development of REBCO Superconducting Transformers With a Current Limiting Function | [
"Electrical and Electronic Engineering",
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | ||
After all - Logging for you | [
"Electrical and Electronic Engineering"
] | ||
The role of atomic oxygen in the decomposition of self-assembled monolayers during area-selective atomic layer deposition | [
"Surfaces, Coatings and Films",
"Condensed Matter Physics",
"Surfaces and Interfaces"
] | ||
QUERIES | [
"History",
"Oceanography"
] | ||
STREET SCENE TOWNSCAPE FOR URBAN REDEVELOPMENT IN MARUNOUCHI(Urban Planning) | [
"Building and Construction",
"Architecture"
] | ||
Modern Treatment Outcomes in Sinonasal Malignancies | [
"Neurology (clinical)",
"Otorhinolaryngology",
"Immunology and Allergy",
"Surgery"
] | ||
Variants in microRNA genes in familial papillary thyroid carcinoma | [
"Oncology"
] | ||
A Distance-Based Two-Stage Ecological Driving System Using an Estimation of Distribution Algorithm and Model Predictive Control | [
"Electrical and Electronic Engineering",
"Computer Networks and Communications",
"Aerospace Engineering",
"Automotive Engineering"
] | ||
TNFα promoter polymorphism is a risk factor for susceptibility in hepatocellular carcinoma in Korean population | Clinica Chimica Acta | [
"Biochemistry (medical)",
"Clinical Biochemistry",
"Biochemistry"
] | |
Automated web usage data mining and recommendation system using K-Nearest Neighbor (KNN) classification method | [
"Computer Science Applications",
"Information Systems",
"Software"
] | ||
Reducing Crime Through Police-Community Relations: Evidence of the Effectiveness of Police-Community Relations Training from a Study of 161 Cities | Policy Studies Journal | [
"Management, Monitoring, Policy and Law",
"Public Administration",
"Sociology and Political Science"
] | |
Announcement | Environmental and Experimental Botany | [
"Plant Science",
"Agronomy and Crop Science",
"Ecology, Evolution, Behavior and Systematics"
] | |
Private Investment in Hospitals: A Comparison of Three Healthcare Systems and Possible Implications for Real Estate Strategies | Objectives: This article explores lessons to be learned from three different healthcare systems and the possible implications for the management of healthcare real estate, in particular in connection to the Dutch system. It discusses similarities and differences among the different systems, in search of possible consequences on cost, financing, and design innovation. Background: To keep healthcare affordable in the future, the Dutch government is currently in the process of changing legislation to move from a centrally directed system to a so-called regulated market system. The deregulation of real estate investment that accompanies the new healthcare delivery system offers healthcare organizations new opportunities, but also more responsibility and greater risk in return on investment. Consequently, healthcare organizations must find new methods of financing. Private investment is one of the options. Methods: Three healthcare systems were analyzed on the basis of a literature review and document analysis, then schematized to show similarities and dissimilarities with regard to private investment in hospitals. Observations are based on a selection of recently published articles on private-sector financing and its implications for healthcare real estate decision making in the Netherlands, the United Kingdom, and Germany. Results: The strengths and weaknesses of three healthcare systems with differing proportions of private and public investment in hospitals were explored. Research revealed a gap between intended effects and actual effects with regard to quality and cost. Costly private finance does not necessarily lead to “value for money.” Transferring real estate decisions to private investors decreases the influence of the healthcare organization on future costs and quality. Conclusions: The three healthcare systems show substantial differences between public and private responsibilities. Less governmental involvement affords both opportunities and risks for hospitals. Private investment may lead to innovation, improved efficiency, and cost reduction, provided that the costs and benefits of decisions are not separated between different stakeholders. A missing link between infrastructure provision and healthcare delivery may impede design innovation and optimal adaptation to work processes and could lead to an inefficient allocation of risks and benefits. | HERD: Health Environments Research & Design Journal | [
"Critical Care and Intensive Care Medicine",
"Public Health, Environmental and Occupational Health"
] |
Issue Information | Liver International | [
"Hepatology"
] | |
A measure of graph vulnerability: scattering number | [
"Mathematics (miscellaneous)"
] | ||
CEPI prepares for future pandemics and epidemics | [
"Infectious Diseases"
] | ||
Lactic Acidosis in Childhood | Advances in Pediatrics | [
"Pediatrics, Perinatology and Child Health"
] | |
Migration and the Media: Debating Chinese Migration to Italy, 1992–2012. By Gaoheng Zhang. Toronto: University of Toronto Press, 2019. 296 pp. ISBN: 9781442630437 (cloth). | [
"History",
"Cultural Studies"
] | ||
The Viability of Branch Libraries | A simple model of a two-stage hierarchical library system is described. The model indicates, in terms of "user costs" and library "viability", how the branch library should be stocked. The most significant factor used in the analysis is shown to be the ratio of the two actual user costs, rather than the actual costs themselves. It is shown that the viability level of stock provision of the branch library is determined by this ratio. | Journal of librarianship | [
"Pharmacology (medical)"
] |
Teacher's PAT? Multiple‐role principal–agent theory, education politics, and bureaucrat power | [
"Education"
] | ||
Structural studies on cyclopentadienyl compounds of trivalent cerium: tetrameric (MeC5H4)3Ce and monomeric (Me3SiC5H4)3Ce and [(Me3Si)2C5H3]3Ce and their coordination chemistry | Organometallics | [
"Inorganic Chemistry",
"Organic Chemistry",
"Physical and Theoretical Chemistry"
] | |
Risk factors associated with early smoking onset in two large birth cohorts | [
"Psychiatry and Mental Health",
"Toxicology",
"Clinical Psychology",
"Medicine (miscellaneous)"
] | ||
Hadronic properties from lattice QCD with dynamical quarks | [
"Nuclear and High Energy Physics"
] | ||
PROBLEMS AND PROSPECTS OF RUSSIA'S MIGRATION POLICY | [
"Management of Technology and Innovation"
] | ||
Certification of bilirubin SRM 916a | [
"Biochemistry",
"Analytical Chemistry"
] | ||
Antiganglioside antibodies in Guillain–Barré syndrome and its related conditions | [
"Pharmacology (medical)",
"Neurology (clinical)"
] | ||
Modeling, analysis, and code/data validation of DIII-D tokamak divertor experiments on ELM and non-ELM plasma tungsten sputtering erosion | Abstract We analyzed recent DIII-D tokamak tungsten divertor probe experiments using advanced, coupled, sputter erosion/redeposition, plasma, and surface response code packages. Modeling is done for ELMing H-mode, and L-mode plasmas, impinging on various size tungsten deposits on Divertor Material Evaluation System (DiMES) carbon probes. The simulations compute 3D, full kinetic, sub-gyromotion, impurity sputtering and transport, including changes in tungsten surface composition and response due to mixed deuterium and carbon ions irradiation. Per our analysis, ELM (edge localized mode) plasma sputtering in DIII-D mostly involves free-streaming high energy (∼500–1000 eV) D+ and C+6 ions, with high near-surface plasma density. L-Mode sputtering is due to impurity sputtering (C, W) only, with lower density. All cases show complete redeposition of tungsten on the divertor, with significant redeposition on the tungsten spots themselves, and low self-sputtering. Comparison of ELM plasma gross tungsten erosion simulation results with in-situ spectroscopic data is good, as are code/data comparisons of net erosion using post-exposure Rutherford backscattering (RBS) data for the L-mode probes. The analysis, extrapolated to a full tungsten divertor, implies low net erosion and negligible plasma contamination from sputtering. These results support the use of high-Z plasma facing surfaces in ITER and beyond. | Nuclear Fusion | [
"Condensed Matter Physics",
"Nuclear and High Energy Physics"
] |
Development of the League of Nations Idea. Documents and Correspondence of Theodore Marburg. Two volumes. Edited by J. H. Latané. (New York: Macmillan Company. 1932. Pp. xv, 480; vii, 483–886. $8.00.) | [
"Museology",
"Archeology",
"History"
] | ||
The increase of impervious cover and decrease of tree cover within urban areas globally (2012–2017) | Urban Forestry & Urban Greening | [
"Soil Science",
"Ecology",
"Forestry"
] | |
A Wedding Dress Worn by the Danish Princess Sophia Magdalena in 1766 | [
"History"
] | ||
E2 Supplementation Selectively Relieves GH’s Autonegative Feedback on GH-Releasing Peptide-2-Stimulated GH Secretion | Female gender confers resistance to GH autonegative feedback in the adult rat, thereby suggesting gonadal or estrogenic modulation of autoregulation of the somatotropic axis. Here we test the clinical hypothesis that short-term E2 replacement in ovariprival women reduces GH’s repression of spontaneous, GHRH-, and GH-releasing peptide (GHRP)-stimulated GH secretion. To this end, we appraised GH autoinhibition in nine healthy postmenopausal volunteers during a prospective, randomly ordered supplementation with placebo vs. E [1 mg micronized 17β-E2 orally twice daily for 6–23 d]. The GH autofeedback paradigm consisted of a 6-min pulsed iv infusion of recombinant human GH (10 μg/kg square-wave injection) or saline (control) followed by iv bolus GHRH (1 μg/kg), GHRP-2 (1μ g/kg), or saline 2 h later. Blood was sampled every 10 min and serum GH concentrations were measured by chemiluminescence. Poststimulus GH release was quantitated by multiparameter deconvolution analysis using published biexponential kinetics and by the incremental peak serum GH concentration response (maximal poststimulus value minus prepeak nadir). Outcomes were analyzed on the logarithmic scale by mixed-effects ANOVA at a multiple-comparison type I error rate of 0.05. E2 supplementation increased the (mean ± sem) serum E2 concentration from 43 ± 1.8 (control) to 121 ± 4 pg/ml (E2) (158 ± 6.6 to 440 ± 15 pmol/liter; P < 0.001), lowered the 0800 h (preinfusion) serum IGF-I concentration from 127 ± 7.7 to 73 ± 3.6μ g/liter (P < 0.01), and amplified spontaneous pulsatile GH production from 7.5 ± 1.1 to 13 ± 2.3μ g/liter per 6 h (P = 0.020). In the absence of exogenously imposed GH autofeedback, E2 replacement enhanced the stimulatory effect of GHRP-2 on incremental peak GH release by 1.58-fold [95% confidence interval, 1.2- to 2.1-fold] (P = 0.0034) but did not alter the action of GHRH (0.83-fold [0.62- to 1.1-fold]). In the E2-deficient state, bolus GH infusion significantly inhibited subsequent spontaneous, GHRH-, and GHRP-induced incremental peak GH responses by, respectively, 33% (1–55%; P = 0.044 vs. saline), 79% (68–86%; P < 0.0001), and 54% (32–69%; P = 0.0002). E2 repletion failed to influence GH autofeedback on either spontaneous or GHRH-stimulated incremental peak GH output. In contrast, E2 replenishment augmented the GHRP-2-stimulated incremental peak GH response in the face of GH autoinhibition by 1.7-fold (1.2- to 2.5-fold; P = 0.009). Mechanistically, the latter effect of E2 mirrored its enhancement of GH-repressed/GHRP-2-stimulated GH secretory pulse mass, which rose by 1.5-fold (0.95- to 2.5-fold over placebo; P = 0.078). In summary, the present clinical investigation documents the ability of short-term oral E2 supplementation in postmenopausal women to selectively rescue GHRP-2 (but not spontaneous or GHRH)-stimulated GH secretion from autonegative feedback. The secretagogue specificity of E’s relief of GH autoinhibition suggests that this sex steroid may enhance activity of the hypothalamopituitary GHRP-receptor/effector pathway. | The Journal of Clinical Endocrinology & Metabolism | [
"Biochemistry (medical)",
"Clinical Biochemistry",
"Endocrinology",
"Biochemistry",
"Endocrinology, Diabetes and Metabolism"
] |
Effects of Ce content on microstructure evolution and magnetic properties for hot deformed Ce–Fe–B magnets | [
"Materials Chemistry",
"Metals and Alloys",
"Mechanical Engineering",
"Mechanics of Materials"
] | ||
Problem and Method: The Possibility of Comparative Study—Using “Lun Liujia Yaozhi” as an Example | On the basis of general characteristics, comparative studies can be restricted by cross-cultural comparison in a narrow sense. In this paper, I take “Chinese philosophy” as an example to investigate the current problems within comparative studies. However, it is possible to embark on comparative study. “Lun Liujia Yaozhi” 论六家要旨 (“Discussion on the Main Points of the Six Schools”) conducts a successful comparison, from which we can extract the comparative method of “Problem and Method,” and it points directly to the basic structure of survival activities, and furnishes the possibility for cross-cultural comparisons. | Frontiers of Philosophy in China | [
"Philosophy"
] |
Relationship of young adult Chinese Americans with their parents: Variation by migratory status and cultural orientation. | American Journal of Orthopsychiatry | [
"Psychiatry and Mental Health",
"Psychology (miscellaneous)",
"Arts and Humanities (miscellaneous)",
"Developmental and Educational Psychology"
] | |
Intestinal helminths and malnutrition are independently associated with protection from cerebral malaria in Thailand | Annals of Tropical Medicine & Parasitology | [
"Infectious Diseases",
"Parasitology"
] | |
Fluorescence Control on Panchromatic Spectra via C-Alkylation on Arylated Quinoxalines | [
"Organic Chemistry"
] | ||
Comparison of two methods for performing treatment reviews by pharmacists and general practitioners for home-dwelling elderly people | Journal of Evaluation in Clinical Practice | [
"Public Health, Environmental and Occupational Health",
"Health Policy"
] | |
Automatable Verification of Sequential Consistency | [
"Computational Theory and Mathematics",
"Theoretical Computer Science"
] | ||
The formation of superinfection-double lysogens of phage λ in Escherichia coli K12 | Virology | [
"Virology"
] | |
Disentangling the microbial ecological factors impacting honey bee susceptibility to Paenibacillus larvae infection | [
"Virology",
"Infectious Diseases",
"Microbiology (medical)",
"Microbiology"
] | ||
195 RANDOMISED TRIAL OF LAPAROSCOPIC NISSEN VS. ANTERIOR 180 DEGREE PARTIAL FUNDOPLICATION—LATE CLINICAL OUTCOMES AT 15–20 YEARS | Abstract Laparoscopic Nissen fundoplication for gastro-oesophageal reflux is followed by troublesome side effects in some patients. Partial fundoplications are proposed for reflux control with less side effects. We reported earlier outcomes from a randomised control trial of Nissen vs. anterior 180° partial fundoplication, with a good outcome following anterior 180° partial fundoplication at up to 10 years follow-up. For this study we determined very late clinical outcomes at up to 20 years follow-up. Methods 107 patients were randomised to Nissen vs. anterior 180° partial fundoplication. 15–20 year follow-up data was available for 79 (41 Nissen, 38 anterior). Outcome was assessed using a standardised clinical questionnaire that included 0–10 analogue scores and yes/no questions to evaluate reflux symptoms, side-effects and overall satisfaction with surgery. Results Heartburn (mean score 3.2 vs 1.4, p = 0.001) and proton pump inhibitor use (41.7% vs 17.1%, p = 0.023) were higher, dysphagia for solids (mean score 1.8 vs 3.3, p = 0.015) was less, and ability to belch was better preserved (84.2% vs 65.9%, p = 0.030) after anterior fundoplication. Overall outcome measures were similar for both groups (mean satisfaction score 8.4 vs 8.0, p = 0.444; 86.8% vs 90.2% satisfied with outcome). Six patients underwent revision from anterior to Nissen fundoplication for reflux, and 5 from Nissen to partial fundoplication for dysphagia. Two further patients underwent revision following Nissen fundoplication for reflux and paraoesophageal hernia respectively. Conclusion At up to 20 years follow-up Nissen and anterior 180-degree partial fundoplication achieve similar rates over overall success, but with a demonstrable trade-off between better reflux symptom control vs. more side-effects after Nissen fundoplication. | [
"Gastroenterology"
] | |
Prevalence of and risk factors for subjective symptoms in urban preschool children without a cause identified by the guardian | International Archives of Occupational and Environmental Health | [
"Public Health, Environmental and Occupational Health"
] | |
Investigation of fatigue relaxation of luminescence in porous silicon by time-resolved spectroscopy | [
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | ||
Raúl Villagrasa Elias, La red de hospitales en el Aragon medieval (ss. xii- | [
"Literature and Literary Theory",
"Visual Arts and Performing Arts",
"History"
] | ||
Atomic oxygen resistant protective coatings for the hubble space telescope solar array in low earth orbit | [
"Materials Chemistry",
"Surfaces, Coatings and Films",
"Surfaces and Interfaces",
"Condensed Matter Physics"
] | ||
Catalase activity measurement with the disk flotation method | Analytical Biochemistry | [
"Cell Biology",
"Molecular Biology",
"Biochemistry",
"Biophysics"
] | |
Nonapeptides mediate trade-offs in parental care strategy | [
"Behavioral Neuroscience",
"Endocrine and Autonomic Systems",
"Endocrinology"
] | ||
Stability analysis of mode-coupling-assisted microcombs in normal dispersion | We theoretically study the stability of mode-coupling-assisted frequency comb generation in normal-dispersion microresonators. With the aid of mode coupling, quantitative analysis of the modulational instability is explored in the parameter space of pump power and detuning. By exploring the coupled mode number, dispersion, and coupling strength in the normalized Lugiato-Lefever model, the modulational stability gain exists and yields extended spatial structures within the regime of eigenvalue bifurcations. Moreover, the dynamics and efficiency of microcombs are discussed, providing the accessibility of high-efficient, stable, and controllable combs. This work offers universal guidelines for operating mode-coupling-assisted combs in a normal-dispersion system. | Optics Express | [
"Atomic and Molecular Physics, and Optics"
] |
Automated eyes watch plants grow: Crop scientists hope to replace traditional painstaking monitoring methods - [News] | IEEE Spectrum | [
"Electrical and Electronic Engineering"
] | |
A Controlled Trial of an Educational Pamphlet to Prevent Disability After Occupational Low Back Injury | [
"Neurology (clinical)",
"Orthopedics and Sports Medicine"
] | ||
Diagnosis of Trypanosomiasis in Experimental Mice and Field-Infected Camels by Detection of Antibody to Trypanosome Tyrosine Aminotransferase | [
"Ecology, Evolution, Behavior and Systematics",
"Parasitology"
] | ||
Activation-independent exposure of the GPIIb-IIIa fibrinogen receptor | Thrombosis Research | [
"Hematology"
] | |
Short communication: Cow- and herd-level prevalence of hypoglycemia in hyperketonemic postpartum dairy cows | [
"Genetics",
"Animal Science and Zoology",
"Food Science"
] | ||
West Nile Virus and Usutu Virus Co-Circulation in Europe: Epidemiology and Implications | West Nile virus (WNV) and Usutu virus (USUV) are neurotropic mosquito-borne flaviviruses that may infect humans. Although WNV is much more widespread and plays a much larger role in human health, the two viruses are characterized by similar envelope antigens, clinical manifestations, and present overlapping in terms of geographic range of transmission, host, and vector species. This review highlights some of the most relevant aspects of WNV and USUV human infections in Europe, and the possible implications of their co-circulation. | [
"Virology",
"Microbiology (medical)",
"Microbiology"
] | |
1H NMR relaxation studies of molten salts containing ethylaluminum dichloride | Inorganica Chimica Acta | [
"Materials Chemistry",
"Inorganic Chemistry",
"Physical and Theoretical Chemistry"
] | |
Infrared and Raman spectra, conformations and ab initio calculations of chloromethyl methyldifluorosilane | Journal of Molecular Structure | [
"Inorganic Chemistry",
"Organic Chemistry",
"Spectroscopy",
"Analytical Chemistry"
] | |
EDITORIAL NOTES | [
"Sociology and Political Science",
"Geography, Planning and Development"
] | ||
The Asymmetric Effects of Macroeconomic Performance on Happiness: Evidence for the EU | [
"Economics, Econometrics and Finance (miscellaneous)",
"Business, Management and Accounting (miscellaneous)"
] | ||
A novel bionic-based substructure division method for topology optimization | [
"Safety, Risk, Reliability and Quality",
"Building and Construction",
"Architecture",
"Civil and Structural Engineering"
] | ||
Sequential and coordinative processing dynamics in figural transformations across the life span | [
"Cognitive Neuroscience",
"Linguistics and Language",
"Developmental and Educational Psychology",
"Language and Linguistics",
"Experimental and Cognitive Psychology"
] | ||
Infiltration and combustion synthesis of an intermetallic compound Ni3Al | [
"Mechanical Engineering",
"Mechanics of Materials",
"Condensed Matter Physics"
] | ||
Impacto da fisioterapia no tratamento da vertigem | . | Revista Neurociências | [
"Neurology (clinical)",
"Neurology"
] |
Monomeric Metal Aqua Complexes in the Interlayer Space of Montmorillonites as Strong Lewis Acid Catalysts for Heterogeneous Carbon-Carbon Bond-Forming Reactions | [
"Catalysis",
"Organic Chemistry"
] | ||
Follow-up by one- and two-dimensional NMR of plasma from pigs with ischemia-induced acute liver failure treated with a bioartificial liver | [
"Spectroscopy",
"Radiology, Nuclear Medicine and Imaging",
"Molecular Medicine"
] |
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