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10,010,803 | Phase II evaluation of vindesine for patients with advanced colorectal carcinoma. | [
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10,010,804 | Phase II trial of thioproline in advanced epidermoid head and neck tumors. | [
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10,010,805 | Vindesine-associated angina and ECG changes. | [
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10,010,806 | Contamination of marihuana cigarettes with pathogenic bacteria--possible source of infection in cancer patients. | [
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10,010,807 | Isolation and characterization of goat submaxillary-mucin. | [
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10,010,808 | Mucin from the submaxillary glands of goats was isolated by precipitation from an aqueous extract with a cationic detergent, followed by dissolution in CaCl2 solution, and fractionation on a DEAE-cellulose column, Five homogeneous, mucin fractions were isolated by NaCl-gradient elution of the column. One of the fractio... | [
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10,010,809 | A sensitive, fluorimetric analysis of amino sugars. | [
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10,010,810 | An antitumor activity of the alkali-soluble polysaccharide (and its derivatives) obtained from the sclerotia of Grifora umbellata (Fr.) Pilát. | [
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10,010,811 | Preparation of some (1 goes to 6)-linked disaccharides, and their derivatives suitable for protein modification. | [
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10,010,812 | Synthetic methods for the preparation of per-O-acetylated, (1 goes to 6)-linked disaccharides containing either a D-galactose or a D-glucose residue at the reducing end are described. In these methods, 1,2,3,4-tetra-O-acetyl-6-O-trityl-beta-D-glucopyranose was first converted into 1,2,3,4-tetra-O-acetyl-beta-D-glucopyr... | [
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10,010,813 | Preparation of new omega-aldehydoalkyl 1-thio-D-glycopyranosides, and their coupling to bovine serum albumin by reductive alkylation. | [
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10,010,814 | Synthesis of two omega-aldehydoalkyl 1-thioglycosides of D-glucopyranose and of D-galactopyranose is described. 3-Oxopropyl and 2-oxoethyl 1-thioglycosides were prepared by treating a tetra-O-acetyl-1-thioaldose with either acrolein or 2-bromo-acetaldehyde, followed by O-deacetylation under mild conditions. These omega... | [
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10,010,815 | Isolation and partial characterization of an extracellular glucansucrase from Leuconostoc mesenteroides NRRL B-1355 that synthesizes an alternating (1 goes to 6), (1 goes to 3)-alpha-D-glucan. | [
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10,010,816 | Leuconostoc mesenteroides NRRL B-1355 grows on sucrose to produce two extracellular alpha-D-glucans. Although both are termed dextrans, they are chemically and physically distinct, and can be separated by fractional ethanol precipitation into fractions designated L and S. Fraction L is similar to B-512F dextran, having... | [
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10,010,817 | Interpretation of aortic root angiography in dogs and in humans. | [
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10,010,818 | It has been suggested that aortic root angiography shows the opening of the aortic valve in humans to be triangular. We investigated whether aortic root angiography does indeed permit determination of area and configuration of the aortic valve. Various angiographic views of the aortic valve were recorded in dogs and hu... | [
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10,010,819 | Body potassium content and capacity of elderly individuals with and without cardiac failure. | [
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10,010,820 | Without some measure of potassium capacity it is impossible to determine whether an individual is potassium depleted or not. Whilst weight is a useful measure of capacity in some circumstances, it is less than adequate in elderly individuals wih chronic cardiac failure. Whole body potassium has been measured in 139 pat... | [
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10,010,821 | Measurement of instantaneous blood-flow velocity in the human aorta using pulsed Doppler ultrasound. | [
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10,010,822 | The reproducibility and ease of use of a pulsed Doppler system has been investigated in 27 normal subjects. Measurements were performed in the ascending aorta and the aortic arch in the sitting and supine position. Good quality recordings were obtained in over 90% of the subjects. Maximum velocities of 120 and 108 cm .... | [
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10,010,823 | Physiological influences on perfusion imaging in transient myocardial ischaemia: importance of early distribution of thallium-201. | [
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10,010,824 | We tested the hypothesis that visualisation of defects on thallium-201 (201Tl) myocardial perfusion images (MPI) depends on the duration of the ischaemic state between 201Tl injection and the time of reperfusion of an occluded coronary artery. Praecordial imaging with a gamma camera was performed in 24 anaesthetised, o... | [
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10,010,825 | [New trends in the care of elderly patients. Comments before the United Nations meeting on aging in 1982]. | [
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10,010,826 | [Scintiscan visualization of acute myocardial infarction using 99mTc-labelled gluconate (author's transl)]. | [
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10,010,827 | [Secondary prevention in coronary syndrome patients up to the age of 55 (author's transl)]. | [
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10,010,828 | [Hepaga, a new Czechoslovak-made specific anti-HBs immunoglobulin (author's transl)]. | [
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10,010,829 | [Levamisole and its effect on the release of lysosomal enzymes from human polymorphonuclear leucocytes (author's transl)]. | [
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10,010,830 | [Investigation of bone marrow in preclinical safety tests of new drugs (author's transl)]. | [
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10,010,831 | [The sociopolitical character of medicine]. | [
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10,010,832 | [Pharmacokinetics of azlocillin (author's transl)]. | [
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10,010,833 | [Chromatographic separation and densitofluorometric determination of porphyrins in thin layer--a diagnostic method for porphyria (author's transl)]. | [
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10,010,834 | [HLA antigen typing in cells of human cell lines--some experience (author's transl)]. | [
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10,010,835 | [Pharmacotherapy in sleeping sickness (author's transl)]. | [
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10,010,836 | [Economic questions in clinical biochemistry (author's transl)]. | [
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10,010,837 | [The significance of oxaluria reduction in pyridoxine prevention of Ca-oxalate nephrolithiasis (author's transl)]. | [
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10,010,838 | [Inconsistent findings between electroencephalography and computerized axial tomography (author's transl)]. | [
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10,010,839 | [Clinical picture of tularemia contracted through the alimentary tract in older age individuals (author's transl)]. | [
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10,010,840 | [Performance parameters in different types of haemodialyzers in vitro (author's transl)]. | [
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... |
10,010,841 | [Do haemodialyzer membranes let through HBsAg? (author's transl)]. | [
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10,010,842 | Production of presumptive humoral haematopoietic regulators in canine cyclic haematopoiesis. | [
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10,010,843 | Conditioned media (CM) were prepared according to previously published techniques from the bone marrow of dogs with cyclic haematopoiesis (CH). CM prepared from day 9 marrows inhibited mouse bone marrow CFU-s proliferation rate while CM from day 10 marrows were stimulatory and also contained an erythroid stimulating fa... | [
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10,010,844 | Presence of pluripotent haemopoietic precursors in vitro (CFU-mix) in haemopoietic tissues from mice of W/Wv genotype. | [
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10,010,845 | The presence or absence of haemopoietic precursors, which produce mixed colonies in vitro (CFU-mix) was examined in the bone marrow and spleen of (WB X C57BL/6) F1-W/Wv mice. Despite the failure of macroscopically evident colony-formation in the spleens of irradiated mice, haemopoietic cells of W/Wv mice did produce ma... | [
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10,010,846 | Partial purification of a low molecular weight inhibitor of epidermal DNA synthesis. | [
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10,010,847 | An attempt has been made to purify factors present in aqueous extracts of pig epidermis which inhibit epidermal cell proliferation. A lipophilic factor of low molecular weight (less than 10,000), has been shown to inhibit DNA synthesis as measured by the uptake of tritiated thymidine in mouse ear epidermis. Purificatio... | [
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10,010,848 | Analysis of the effect of hydroxyurea on stem cell (CFU-s) kinetics. | [
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10,010,849 | Hydroxyurea induces profound changes in the pluripotential haemopoietic stem cell (CFU-s) kinetics. The main feature of these changes is a synchronous entry of resting G0 CFU-s into the cell cycle. The analysis of the passage of the CFU-s cohort through the cell cycle has been largely based on the examination of the fr... | [
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10,010,850 | A long-lived thymidine pool in epithelial stem cells. | [
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10,010,851 | The labelling index (LI) of the individual basal cell positions of the anterior column of mouse tongue filiform papillae was assessed with time after an injection of [3H]TdR at 12.00 hours (the minimum point in the circadian LI rhythm). An initial doubling of the LI in the stem cell zone due to cell division was follow... | [
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10,010,852 | Velocity sedimentation profiles of normal and regenerating primitive erythroid burst-forming units: relation to phase of cell cycle and growth in vitro. | [
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10,010,853 | The primitive burst-forming unit-erythroid (BFU-e) derived from normal and regenerating murine bone marrow was examined by velocity sedimentation at unit gravity. An increase in the modal sedimentation velocity and the percentage of rapidly sedimenting BFU-e was found in regenerating marrow as compared to normal marrow... | [
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10,010,854 | A comparative study on wound-healing in neonatal and adult mouse epidermis in vivo. | [
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0.076694... |
10,010,855 | A cut made into the back skin of either newborn or adult mice evokes, at both ages, a hyperproliferative response in the epidermis. Differences in the reaction of neonatal as compared with adult epidermis are found in the spatial distribution of proliferative activity as well as in its time course. The response in adul... | [
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0.0661... |
10,010,856 | Radiosensitivity variation during the cell cycle in pronuclear mouse embryos in vitro. | [
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0.0563... |
10,010,857 | The radiosensitivity of pronuclear mouse (B6D2 F2 X ICR) embyros has been measured in vitro as a function of time during the cell cycle. This was done by measuring the dose of X-rays (LD50) required to prevent development of 50% of the pronuclear embryos to the blastocyst stage in 5 days of culture. The LD50 was found ... | [
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10,010,858 | Morphogenesis of the renal juxtaglomerular apparatus and peripolar cells in the sheep. | [
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0.02... |
10,010,859 | The morphogenesis of the juxtaglomerular apparatus and peripolar cells was studied in the metanephros of fetal sheep (from 24 to 147 days of gestation) using light and electron microscopy. The first juxtaglomerular apparatus was detected at 45 days of gestation, following constriction of the edges of Bowman's capsule a... | [
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10,010,860 | Physiological and cytochemical studies on activator calcium in contraction by smooth muscle of a sea cucumber, Isostichopus badionotus. | [
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0.0039805... |
10,010,861 | The physiological properties of mechanical responses and the intracellular localization and translocation of calcium as a pyroantimonate precipitate were studied in the longitudinal retractor muscle (LRM) of a Bermuda sea cucumber. Acetylcholine (ACh)-induced contraction was reduced by lowering the external Ca concentr... | [
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10,010,862 | Endocytosis in absorptive cells of cultured human small-intestinal tissue: effect of cytochalasin B and D. | [
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10,010,863 | The effect of cytochalasin B (CB) and cytochalasin D (CD) on the endocytotic uptake of horseradish peroxidase (HRP) by intestinal absorptive cells was investigated by morphometric methods. The results showed that CD inhibited endocytosis considerably, and without any detrimental side-effects. CB had hardly any effect o... | [
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0.02425... |
10,010,864 | Aspects of the structure and development of monotreme spermatozoa and their relevance to the evolution of mammalian sperm morphology. | [
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0.104... |
10,010,865 | The elongated spermatid nuclei of monotremes exhibit a circumferentially arranged spiral pattern of chromatin condensation, and ultimately form helical filiform sperm heads up to 50 microns long and either circular or slightly oval in transverse section. The acrosome is formed by the collapse of the proacrosomal vacuol... | [
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0.03... |
10,010,866 | Fine structure of seminiferous tubules from prenatally irradiated rats. | [
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0.0995544... |
10,010,867 | The ultrastructure of the seminiferous tubules was studied in rats that had been subjected to whole body irradiation on the 19th day of gestation. The seminiferous tubules from 3 months-old irradiated animals are devoid of germ cells and contain only Sertoli cells. Compared with controls of the same age, the seminifero... | [
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0.0536... |
10,010,868 | Fine structure and cytochemistry of peroxisomes (microbodies) Leptomonas samueli. | [
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0.0... |
10,010,869 | Leptomonas samueli possesses in its cytoplasm a membrane-bounded organelle which can reach a length of 2.8 microns and a diameter of 0.2 microns. Catalase activity, which is inhibited by 3-amino-1, 2, 4-triazole, was detected at the ultrastructural level in the matrix of the organelle by using an alkaline diaminobenzid... | [
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10,010,870 | Pigment biogenesis in freshwater shrimp ventral nerve chord chromatophores. | [
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10,010,871 | The possible biogenesis of two pigment granule types present in the monochromatic, brown chromatosomes enveloping the ventral nerve chord of the freshwater palaemonid shrimps Macrobrachium acanthurus, M. heterochirus and M. olfersii is examined by transmission electron microscopy in thin section and freeze fracture rep... | [
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... |
10,010,872 | Pinealocytes contacting the cerebrospinal fluid of the suprapineal recess in the Mongolian gerbil (Meriones unguiculatus). | [
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0.11077... |
10,010,873 | The pineal system of the Mongolian gerbil (Meriones unguiculatus) was investigated by light and electron microscopy, special attention being paid to the sites of contact with the ventricular system. The results reveal that the pineal system of this species has a specific topographical relationship to the suprapineal re... | [
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0.... |
10,010,874 | Formation of membrane-bounded secretory granules in the midgut epithelium of a termite, Cubitermes severus, and a possible intercellular route of discharge. | [
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0.027949... |
10,010,875 | Mature columnar cells of the midgut of Cubitermes contain a prominent secretion product observed at light- and electron-microscopic levels. At the ultrastructural level the product is resolved as an electron dense material contained in vesicles up to 1 micron diameter that accumulate in the apical cytoplasm. The vesicl... | [
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0.0... |
10,010,876 | Morphological studies on neuroglia. IV. Proliferative response of non-neuronal elements in the hippocampus of the rat to kainic acid-induced lesions. | [
0.02141144871711731,
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0.052038270980119705,
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0.04464667662978172,
0.0... |
10,010,877 | Autoradiographic studies showed that in the rat hippocampus "microglia-like reactive cells" (MRS) and astrocytes are capable of proliferation in response to kainic acid (KA)-induced lesions. A marked increase in the number of labeled MRC was observed during the first four days after the induction of the KA-lesion. A pr... | [
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0.02679850533604622,
0.035... |
10,010,878 | Paddle cilia (discocilia) in chemosensitive structures of the gastropod mollusk Pleurobranchaea californica. | [
0.04297807440161705,
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0.03471744433045387,
-0.00561... |
10,010,879 | Scanning electron microscopy of various regions of the body of the marine gastropod Pleurobranchaea californica (McFarland) has revealed a characteristic cell type that bears cilia with dilated discoid-shaped tips. The tips of the cilia consist of an expansion of the ciliary membrane around a looped distal extension of... | [
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0.04134500026702881,
0.009375... |
10,010,880 | The interstitial cells in the colon of the rabbit. Scanning and transmission electron microscopy. | [
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0.094... |
10,010,881 | The interstitial cells associated with the myenteric plexus of the rabbit colon were studied by scanning and transmission electron microscopy. It was demonstrated that the interstitial cells were stellate or fusiform in shape and located over the ganglia, over nerve bundles and between muscle cells. They were character... | [
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0.0589010... |
10,010,882 | Synthesis and migration of proteins and glycoproteins in juxtaglomerular cells of sodium-deficient rats. An ultrastructural radioautographic study. | [
0.02471192181110382,
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0.06828124076128006,
0.0791... |
10,010,883 | Sections of juxtaglomerular cells from sodium-deficient rats were subjected to radioautography after a single intravenous injection of L-tyrosine-3,5 3H or of L-fucose 3H to identify the sites of synthesis and to follow the migration of newly-formed proteins and glycoproteins. As early as 2 min after injection of L-tyr... | [
0.07947549223899841,
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0.0914740115404129,
0.1116554... |
10,010,884 | Unorthodox pattern of microvilli and intercellular junctions in regular retinular cells of the porcellanid crab Petrolisthes. | [
0.027806401252746582,
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0.... |
10,010,885 | 1. Retinular fine structures in compound eyes of the porcellanid crab Petrolisthes differs significantly from two paguroid anomurans Clibanarius and Pagurus which basically conform to the usual conservative decapod crustacean retinular pattern. 2. Bidirectional orientation of microvilli has been discovered in rhabdomer... | [
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0.05039531737565994,
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0.007056570611894131,
0.0294... |
10,010,886 | Exocytotic release of secretory granules from endocrine cells in the midgut of insects. | [
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10,010,887 | Exocytotic release of the secretory granules of the endocrine cells in the midgut of a cockroach, Periplaneta americana, was studied by means of fixation with tannic acid in combination with glutaraldehyde and osmium tetroxide. A sequence of images indicative of exocytosis suggests the following steps in this process: ... | [
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0.0... |
10,010,888 | Distribution of phospholipids labeled with 3H-choline and relationship between membranous organelles in amoebae, as studies by electron-microscopic radioautography. | [
0.017747119069099426,
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0.0... |
10,010,889 | Amoebae were injected with a solution of 3H-choline, and samples were prepared for electron-microscopic radioautography at intervals between 15 min and 24 h thereafter. At the earliest interval, the rough endoplasmic reticulum was the most heavily labeled organelle. At subsequent intervals, the proportion of silver gra... | [
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0.040... |
10,010,890 | Ultrastructural observations on the pineal gland of the Chinese hamster, Cricetulus griseus. I. The superficial pineal. | [
0.06881152093410492,
0.004964443389326334,
0.05337568372488022,
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0.060046... |
10,010,891 | The ultrastructure of the pineal parenchymal cells, pinealocytes and glia-like cells, of the Chinese hamster (Cricetulus griseus) is described. Pinealocyte nuclei contain spindle-shaped inclusions consisting of bundles of closely packed parallel filaments of about 8 nm in thickness. Mitochondria contain lamellar and tu... | [
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0.020512012764811516,
0.007003218401223421,
-0.018231987953186035,
... |
10,010,892 | Ascidian larval tunic: Extraembryonic structures influence morphogenesis. | [
-0.03497392311692238,
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-0.036940161138772964,
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... |
10,010,893 | The larval tunic of Corella inflata is composed of two cuticular layers, extracellular filaments and ground substance. It lies outside the epidermis and most of it is known to be produced by the epidermis. The dorsal, ventral and caudal fins are specialized parts of the tunic that are essential for larval locomotion. T... | [
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0.05065662041306496,
0.08601338416337967,
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-0.08706789463758469,
0.04486... |
10,010,894 | A morphometric analysis of regional differences in myotomal muscle ultrastructure in the juvenile eel (Anguilla anguilla L.). | [
0.06899838149547577,
0.024959303438663483,
0.038198746740818024,
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0.02107015997171402,
0.086... |
10,010,895 | Subpopulations of fast and slow fibres within the trunk musculature of elvers were examined using morphometric analysis of electron micrographs. Fibre regions were characterised by their histochemical staining characteristics, and individual fibres located using a coordinate mapping system utilising morphological featu... | [
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0.10156777501106262,
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0.04771334305405617,
0.03114481... |
10,010,896 | The demonstration of calcium in the axonal granules of the peripheral nervous system of male Schistosoma mansoni by X-ray microanalysis. | [
0.056115806102752686,
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0.032584723085165024,
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0.06225179135799408,
0.078... |
10,010,897 | A conspicuous feature of freeze-dried cryosections of male Schistosoma mansoni is the presence of groups of electron-dense granules. X-ray analysis in the TEM of these granules shows them, in comparison with the adjacent cytoplasm, to contain significantly greater amounts of sodium and calcium. In glutaraldehyde-fixed ... | [
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0.040176160633563995,
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0.04137003421783447,
0... |
10,010,898 | Evidence for the presence of osseous tissue in dogfish vertebrae. | [
-0.02997119352221489,
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0.022650782018899918,
0.03934571146965027,
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0.0257093645632267,
0.06... |
10,010,899 | The calcified cartilage of the dogfish vertebra has been studied by means of an undecalcified hard tissue method, including microradiography and tetracycline labelling, and electron microscopy. The transversely sectioned vertebra shows a centrum and neural and hemal arches. The mineralized area consists of a narrow but... | [
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0.028507903218269348,
0.021741053089499474,
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0.03467101976275444,
0.... |
10,010,900 | A scanning electron microscopic study of the boundary zone of the human spleen. | [
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0.01313474215567112,
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0.022964607924222946,
0.068... |
10,010,901 | The structural characteristics and cellular elements of the boundary zone between the white and red pulp of the human spleen were studied by SEM and TEM. The boundary zone consisted of both the perifollicular region and the region surrounding the periarterial lymphoid sheath. The perifollicular region was further subdi... | [
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0.001241847756318748,
0.021538402885198593,
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0.040573544800281525,
... |
10,010,902 | Development of the tympanal organ in larvae of the migratory locust (Locusta migratoria). | [
0.04095339775085449,
0.03946303576231003,
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0.08768288791179657,
0.10575928539037704,
-0.08185490220785141,
-0.04811374470591545,
0.0019... |
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