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10,001,400 | The concentration of metallothionein (MT) in the liver of the perinatal rat is relatively high at term and 7 days after birth and then decreases to barely detectable levels by day 28. The developmental pattern MT-zinc parallels that of MT. When challenged with a single injection of cadmium chloride, the 26-day-old rat ... | [
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10,001,401 | Estrogen in high doses inhibits perphenazine-induced prolactin release. | [
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10,001,402 | We investigated the effects of high doses of estrogen on the basal and stimulated secretion of PRL. Daily administration of 0.1 micrograms estradiol benzoate to female mice for 4 weeks significantly increased the amplitude of PRL release induced by perphenazine. A dose of 1.0 micrograms had no stimulatory effect, while... | [
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10,001,403 | Vasopressin-related peptides increase the hippocampal corticosterone receptor capacity of diabetes insipidus (Brattleboro) rats. | [
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10,001,404 | The binding of [3H]corticosterone to receptors in cytosol of several brain regions and of [3H]dexamethasone to receptors in pituitary cytosol was measured after chronic treatment of homozygous diabetes insipidus rats (Ho-Di) with various neuropeptides. All rats were adrenalectomized 24 h before sacrifice for depletion ... | [
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10,001,405 | Endogenous inhibition of prolactin secretion in pregnant lactating rats. | [
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10,001,406 | The purpose of the present study was to test whether rat placental lactogen, proposed to be inhibitory for endogenous rhythmic PRL secretion during pregnancy, is also inhibitory for a neurally mediated PRL response to exogenous stimulation, i.e. suckling. Pregnant lactating rats were used as the model in this study. Bl... | [
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10,001,407 | Structure-activity relationships of inhibition of hepatic monodeiodination of thyroxine to 3,5,3'-triiodothyronine by thiouracil and related compounds. | [
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10,001,408 | The effects of gonadectomy and testosterone treatment on luteinizing hormone secretion in fetal rhesus monkeys. | [
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10,001,409 | Preferential inhibition of thyroxine and 3,5,3'-triiodothyronine formation by propylthiouracil and methylmercaptoimidazole in thyroid peroxidase-catalyzed iodination of thyroglobulin. | [
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10,001,410 | The present study was undertaken to determine whether the thioureylene antithyroid drugs propylthiouracil [6-propyl-2-thiouracil (PTU)] and methylmercaptoimidazole [1-methyl-2-mercaptoimidazole (MMI)] have a specific inhibitory effect on the thyroid peroxidase (TPO)-catalyzed conversion of diiodotyrosine to T4 (couplin... | [
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10,001,411 | Comprehensive kinetics of triiodothyronine production, distribution, and metabolism in blood and tissue pools of the rat using optimized blood-sampling protocols. | [
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10,001,412 | We have determined estimates for 24 physiological parameters of production, interpool transport, distribution, and metabolism of T3 in the major T3 pools of the unanesthetized male Sprague-Dawley rat, from blood-borne data and a comprehensive model and analysis of this system. Most of these indices have previously been... | [
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10,001,413 | The antiandrogenic effects of delta 1-testolactone (Teslac) in vivo in rats and in vitro in human cultured fibroblasts, rat mammary carcinoma cells, and rat prostate cytosol. | [
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10,001,414 | The antiandrogenic properties of delta 1-testolactone (17 alpha-oxa-D-homo-1,4-androstane-3,17-dione; Teslac) were investigated in vivo and in vitro. Teslac (75 mg/day for 7 days) inhibited the rise in ventral prostate weight induced by testosterone (T) (P less than 0.001), dihydrotestosterone (DHT) (P less than 0.05),... | [
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10,001,415 | Effect of sulfhydryl reagents on the conversion of thyroxine to 3,5,3'-triiodothyronine: direct action on thyroxine molecules. | [
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10,001,416 | Sulfhydryl reagents are good stimulators of the enzymatic conversion of T4 to T3. Previous studies have suggested that the underlying mechanism for this property is that these reagents may serve as a cofactor in the reaction, or they maintain the enzyme in its active reduced form. We examined another possibility, namel... | [
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10,001,417 | Differential stimulation by 17 beta-estradiol and synthetic estrogens of progesterone-receptor and of translocation of estrogen-receptor in rat pituitary and uterus. | [
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10,001,418 | Central and peripheral actions of physiological and synthetic estrogens with elevated biological potencies were investigated. The synthetic estrogens were 1,3-diacetoxy-17 alpha-ethinyl-7 alpha-methyl-1,3,5(10)-estratrien-17 beta-ol (DM-EE2) and 1,3-dibenzoyloxy-17 alpha-ethinyl-7 alpha-methyl-1,3,5(10)-estratrien-17 b... | [
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10,001,419 | Estradiol inhibits prolactin induced alpha-lactalbumin production in normal primate mammary tissue in vitro. | [
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10,001,420 | The effect of estradiol on prolactin induced alpha-lactalbumin production in normal primate mammary tissue was studied by maintaining tissues in organ culture with or without various combinations of oPRL and 17 beta-estradiol. As expected alpha-lactalbumin was increased byoPRL. 17 Beta-estradiol was found to have a sig... | [
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10,001,421 | The possible involvement of intestinal bacteria in steroidal hypertension. | [
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10,001,422 | The bacterial flora of rats ws modified, using antibiotics, in order to interrupt the enterohepatic circulation of steroids excreted in bile. Antibiotic treatment was contined while corticosterone was administered to these animals, and over five days corticosterone raised blood pressures by an average of 9.2 mmHg compa... | [
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10,001,423 | Inhibition of the enzymatic degradation of Met-enkephalin by catecholamines. | [
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10,001,424 | The influence of the catecholamine hormones and some of their metabolites on the enzymatic degradation of met-enkephalin by rat brain homogenates has been evaluated. The enzyme activity was determined by the release of [125I]-tyrosine from radioiodinated met-enkephalin following Porapak Q column chromatography. Each of... | [
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10,001,425 | Parathyroid hormone stimulates mammalian renal 25-hydroxyvitamin D3-1 alpha-hydroxylase in vitro. | [
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10,001,426 | We have shown that parathyroid hormone (PTH) stimulates 25-hydroxyvitamin D2-1 alpha-hydroxylase activity in mitochondrial preparations of guinea pig kidney in vitro.1,25-[3H]dihydroxyvitamin D3 produced from 25-[3H]hydroxyvitamin D3 was identified by both normal phase and reversed-phase high pressure liquid chromatogr... | [
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10,001,427 | Rat placenta is an active site of inner ring deiodination of thyroxine and 3,3',5-triiodothyronine. | [
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10,001,428 | Inner ring deiodination of L-T4 and L-T3 by rat placental homogenates resulted in the generation of rT3 from T4 and 3,3'-diiodothyronine and 3'-monoiodothyronine from T3. Dithiothreitol is required in the incubation medium. There was little or no detectable outer ring deiodination of T4 and T3. These findings suggest t... | [
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10,001,429 | Salivary gland weight and nerve growth factor in the genetically obese (ob/ob) mouse. | [
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10,001,430 | The salivary glands of genetically obese male mice are significantly smaller than those of lean male mice, but the salivary glands of female mice do not differ in weight. The increases in weight of salivary glands in male mice after treatment with T3 at 50, 150, or 500 ng/day or with several doses of isoproterenol were... | [
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10,001,431 | Degradation of rat and human lipoproteins by cultured rat ovary granulosa cells. | [
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10,001,432 | We have investigated the degradation of 125I-labeled rat and human lipoproteins by rat ovary granulosa cells cultured in serum-free medium. The granulosa cells degrade rat [125I]iodo high density lipoprotein (HDL) to acid-soluble products, mainly monoiodotyrosine. The degradation of 125I-labeled rat HDL is a specific, ... | [
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10,001,433 | Relationship of estradiol to luteal function in the cycling baboon. | [
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10,001,434 | Since exogenous 17 beta-estradiol (E2) is luteolytic in some primates, it is reasonable to conclude that endogenous E2 is the naturally occurring luteolytic substance. However, a link between endogenous E2 and spontaneous luteolysis has not been demonstrated. In an attempt to understand the function of E2 in spontaneou... | [
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10,001,435 | Role of the pituitary in restitution of blood volume after hemorrhage. | [
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... |
10,001,436 | Characteristics of inner ring (3 or 5) monodeiodination of 3,5-diiodothyronine in rat liver: evidence suggesting marked similarities of inner and outer ring deiodinases for iodothyronines. | [
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10,001,437 | Xerophthalmia: a review of hospital out-patient records. | [
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0.0431... |
10,001,438 | Management of bronchial asthma in Ethiopian children. | [
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10,001,439 | Glomerulonephritis: A preliminary clinico-pathological report on 29 patients. | [
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10,001,440 | Dental health conditions of students in Ethiopia: findings from the Development Through Cooperation Campaign, 1976-77. | [
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10,001,441 | Preimplantation mouse embryos synthesize membrane sterols. | [
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10,001,442 | Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline. | [
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10,001,443 | The segregation and early migration of cranial neural crest cells in the avian embryo. | [
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0.002... |
10,001,444 | The apical lamina of the sea urchin embryo: major glycoproteins associated with the hyaline layer. | [
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10,001,445 | Neural crest cell behavior in white and dark embryos of Ambystoma mexicanum: epidermal inhibition of pigment cell migration in the white axolotl. | [
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10,001,446 | Isolation of sea urchin embryo histone H2A and immunological identification of other stage-specific H2A proteins. | [
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10,001,447 | The development of the conduction system in the mouse embryo heart. | [
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10,001,448 | The effect of experimentally induced triploidy on the lethal expression of the t(12) mutation in mouse embryos. | [
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10,001,449 | Nuclear morphology of ichthyosis mutant mice as a cell marker in chimeric brain. | [
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10,001,450 | The relationship between cumulus cell-oocyte coupling, oocyte meiotic maturation, and cumulus expansion. | [
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10,001,451 | Persistence of attention to a novel conspecific: some developmental variables in laboratory rats. | [
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10,001,452 | Persistence of social attention by male and female laboratory rats was examined following exposure to novel conspecifics. In experiment I we compared performance of castrate female controls. Testosterone significantly prolonged mean social investigation time. Castrate females treated with a 10-day regimen of testostero... | [
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10,001,453 | Motor asymmetries in preterm infants: effects of prematurity and illness. | [
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10,001,454 | Two types of motor asymmetry, postural asymmetry and lateral head turning, were assessed in 3 groups of preterm infants, one of which had experienced respiratory distress syndrome (RDS) in the postnatal period. Results reveal that maintenance of a right postural asymmetry is present as early as 34 weeks conceptional ag... | [
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10,001,455 | A quantitative analysis of the feeding behavior of suckling rabbits. | [
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10,001,456 | Three experiments are reported on the feeding behavior of suckling rabbits ("kittens"). In the 1st the latency with which the kittens attached to the nipple, and then left the nipple, was determined. Attachment was very rapid and wholly reliable: on the 80 tests the nipple was seized in every case in under 9 sec, and o... | [
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10,001,457 | Ontogeny of hoarding in the golden hamster: the development of motor patterns and their sequential coordination. | [
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10,001,458 | The hoarding behavior of 4 litters of Golden hamster pups (n = 3) was observed every 2nd day between the age of 13 and 47 days (2 litters) or 13 and 55 (2 litters). Each litter lived with the mother until Day 30; then the pups were put in social isolation. Immature forms of pouch filling and emptying, which were not in... | [
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10,001,459 | Maturation and d-amphetamine-induced changes in web building. | [
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10,001,460 | Webs of Araneus diadematus Cl. were obtained under drugged (dextroamphetamine) and control conditions at three age-periods in the development of the spider from juvenility to sexual maturity. Although certain features of construction are affected in all periods and some exhibit differential effects with age, it was not... | [
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10,001,461 | Effect of cross-rearing on species identification in zebra fish and pearl danios. | [
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10,001,462 | Zebra fish and pearl danios were either cross-reared or raised with conspecifics and tested as adults for species preference over 4 days. Subjects were then placed with conspecifics by group for 30 days and retested over 2 days. Initial testing showed less preference (species identification) for conspecifics by cross-r... | [
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10,001,463 | Effects of early social experience on activity and object investigation in the ferret. | [
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10,001,464 | Earlier experiments have shown that many of the effects of early social isolation in the rat may be due to deprivation of social play. The isolated ferret, like the isolated rat, is hyperactive; furthermore, its hyperactivity appears to be related to deprivation of social play. However, the relationship between object ... | [
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10,001,465 | Effect of brain growth stages on T-maze acquisition in mice. | [
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10,001,466 | Recently, it has been shown that brain growth is characterized by periods of especially large increases in growth, with "plateaus" in growth between these "spurt" periods. In humans, these spurts in brain growth are correlated with spurts in mind growth, collectively termed phrenoblysis. Brain growth spurts in rodents ... | [
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10,001,467 | Age and brightness discrimination learning by c57BL/6J mice. | [
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10,001,468 | hyperprolactinemia of portal hypertension in rats. | [
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0.0959... |
10,001,469 | Plasma prolactin levels are often raised in patients with liver cirrhosis and portal hypertension. To obtain more insight into the underlying mechanisms we examined the synthesis and release of prolactin in male rats with partially ligated portal veins. Portal hypertension led to an increase in pituitary prolactin, pla... | [
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10,001,470 | Effects of lactulose and neomycin on urea metabolism in cirrhotic subjects. | [
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0.1053002178668975... |
10,001,471 | In our previous studies of cirrhotic subjects lactulose caused a 25% decrease in the urea production rate associated with a decrease in urinary urea excretion and an increase in stool nitrogen. The decrease in the rate of urea production was an indirect measure of reduction in gut ammonia production. The present study ... | [
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10,001,472 | S-adenosyl-L-methionine antagonizes ethynylestradiol-induced bile cholesterol supersaturation in humans without modifying the estrogen plasma kinetics. | [
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10,001,473 | Previous investigations have shown that S-adenosyl-L-methionine antagonizes both cholestasis and bile lipid alterations induced by ethynylestradiol in the rat. Since it is still unknown whether S-adenosyl-L-methionine prevents ethynylestradiol-induced cholesterol supersaturation of bile in humans also and how methynati... | [
0.07283229380846024,
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0.028917616233229637,
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0.00020526004664134234,
0.04267970472574234,
0.003... |
10,001,474 | Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma. | [
0.11169380694627762,
0.029120245948433876,
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0.002393695991486311,
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-0.03... |
10,001,475 | A prospective trial was performed in which biopsy and cytology specimens were obtained on 202 consecutive patients including 47 with esophageal or gastric carcinomas. The first biopsy specimen yielded a correct diagnosis in the majority of instances: 70% of gastric carcinomas and 93% of esophageal carcinomas. Three add... | [
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0.024158800020813942,
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0.0... |
10,001,476 | Cell renewal and migration in lymphoid follicles of Peyer's patches and cecum--an autoradiographic study in mice. | [
0.00239569041877985,
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0.009104072116315365,
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0.06973783671855927,
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0.001819... |
10,001,477 | Peyer's patch lymphoid follicles are characterized by a cuboidal epithelium, which has low numbers of mucus-secreting goblet cells, infiltration with clusters of lymphoid cells, and unique antigen-transporting M cells. M cells have short, irregular microvilli similar to undifferentiated crypt epithelial cells, which su... | [
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0.06263381987810135,
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0.018193474039435387,
0.03437575697898865,
0.01045775506... |
10,001,478 | Histamine synthesis by intact mast cells from canine fundic mucosa and liver. | [
0.027818450704216957,
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0.11369270086288452,
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0.04638173431158066,
0.084... |
10,001,479 | The synthesis and degradation of histamine by dog fundic mucosa was studied by using cells dispersed by enzymatic digestion and separated sequentially by velocity sedimentation in an elutriator rotor, and by density gradient. Histidine decarboxylase activity was found in appreciable amounts in fractions highly enriched... | [
0.08564628660678864,
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0.04503272473812103,
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0.010531188920140266,
0.0... |
10,001,480 | Gastric mucosal prostaglandin E levels in patients with gastric ulcer disease and carcinoma. | [
0.014652007259428501,
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0.008534611202776432,
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0.039... |
10,001,481 | Prostaglandin E was measured by radioimmunoassay in endoscopic biopsy specimens obtained from 7 normal healthy volunteers, 28 patients with a benign gastric ulcer, and 10 with a malignant gastric ulcer. Biopsy specimens were taken from the antral and body mucosa and from the ulcer edge in patients. The median value in ... | [
0.022592008113861084,
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0.0029080111999064684,
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0.... |
10,001,482 | Luminal lymphoid cells in the rabbit intestine. | [
0.11150605231523514,
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0.060259297490119934,
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0.05640778690576553,
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0.06723717600107193,
0.021089602261781693,
0.04826... |
10,001,483 | In normal rabbits, lymphocytes have been identified in large numbers on the luminal epithelial aspects of both Peyer's patches and the appendix by scanning and transmission electron microscopy. Luminal cells shared an intimate relationship with intestinal microorganisms. Irrigation of the appendiceal lumen has proved a... | [
0.0685282051563263,
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0.058374468237161636,
0.0011923719430342317,
0.032657112926244736,
0.07602640986442566,
0.03790... |
10,001,484 | Inflammatory and structural changes in the opossum esophagus after resection of the cardia. | [
0.0830482766032219,
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0.1086798831820488,
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0.00841047428548336,
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0.06198366731405258,
-0.06592149287462234,
0.0448107... |
10,001,485 | Transmembrane voltage of opossum esophageal smooth muscle and its response to electrical stimulation of intrinsic nerves. | [
0.005275556817650795,
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0.016506412997841835,
0.0604066364467144,
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0.04240153729915619,
0.04075280576944351,
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0.0737182... |
10,001,486 | Effects of experimental chronic hypercalcemia on feline exocrine pancreatic secretion. | [
0.06085612624883652,
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0.028127120807766914,
0.11565853655338287,
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0.03419198840856552,
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0.0005559036508202553,
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0.074973... |
10,001,487 | Regression of biliary cirrhosis following choledochal cyst drainage. | [
0.04781253635883331,
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0.09543750435113907,
0... |
10,001,488 | Invasive enterocolitis caused by Edwardsiella tarda. | [
0.030277132987976074,
0.026321232318878174,
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0.03079879656434059,
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-0.... |
10,001,489 | Lymphoreticular malignancy presenting as fulminant hepatic disease. | [
0.107643723487854,
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0.004832645878195763,
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-0.... |
10,001,490 | Four cases of fulminant hepatic disease caused by lymphoreticular infiltration are described. All 4 patients died within a few weeks and clinical diagnoses included viral hepatitis, alcoholic hepatitis, and drug hepatitis. A diagnosis of malignancy was made prior to autopsy in only 1 of the 4 patients. Autopsies reveal... | [
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0.02638908475637436,
0.... |
10,001,491 | Tissue diagnosis in ulcer gastrointestinal malignancy. | [
0.04353241249918938,
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0.02254737913608551,
-0.04553116485476494,
-0.008190571330487728,
-0.00... |
10,001,492 | Gastric acid secretion, smoke and duodenal ulcer healing. | [
0.032899826765060425,
0.005926103796809912,
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0.10549629479646683,
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0.0072533986531198025,
0.002524213632568717,
-0.0529412217438221,
-0.031... |
10,001,493 | Radioimmunoassay for HBcAg. | [
0.02615830861032009,
0.11372403055429459,
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0.023926710709929466,
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-0.05141472816467285,
-0.05052616447210312,
-0.0208264347165823,
0.01501931... |
10,001,494 | Tuberculosis after cimetidine therapy: an adverse clinical immune effect? | [
0.009481750428676605,
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-0.01607143133878708,
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0.029268009588122368,
0.1170760914683342,
0... |
10,001,495 | Diabetic control and gastrointestinal function. | [
-0.004930058494210243,
0.0022991267032921314,
-0.06684208661317825,
0.057310666888952255,
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-0.005360590294003487,
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0.05815579742193222,
-0.12006771564483643,
-... |
10,001,496 | The intestinal phase of pancreatic polypeptide release. | [
0.05086051672697067,
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0.01056243572384119,
0.02914607711136341,
0.013922632671892643,
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0.02331184595823288,
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0.02699529007077217,
-0.05542125180363655,
0.03676688... |
10,001,497 | Patient acceptance and effectiveness of a balanced lavage solution (Golytely) versus the standard preparation for colonoscopy. | [
0.05115022510290146,
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0.000543964677490294,
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-0.10950293391942978,
0.021658603101968765,
0.08038739114999771,
-0.03664325177669525,
0.04... |
10,001,498 | An oral electrolyte solution containing 125 mM/L sodium, 10 mM/L potassium, 80 mM/L sulfate, 20 mM/L bicarbonate, and 80 mM/L of polyethylene glycol, and associated with little water or electrolyte absorption from the gut was recently described in this journal. To determine the efficacy of this solution (Golytely) for ... | [
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0.017623743042349815,
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0.03236070275306702,
0.08849648386240005,
-0.005627977196127176,
0.08297... |
10,001,499 | Contact electrode method in hydrogen gas clearance technique: a new method for determination of regional gastric mucosal blood flow in animals and humans. | [
0.0195150263607502,
0.03521842509508133,
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-0.1059001237154007,
0.01211483683437109,
-0.03238258883357048,
-0.06911229342222214,
0.0370... |
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