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10,002,700 | Criteria have not been established for differentiating herniated nucleus pulposus and bulging annulus fibrosus by computed tomography (CT). The CT diagnosis of a bulging annulus was evaluated by correlating the CT and anatomic appearance of cadaver lumbar spines, and by comparing CT and surgical findings in patients undergoing lumbar laminectomy. We found that in anatomically or surgically verified bulging annulus, CT showed generalized extension of the disk margin beyond the vertebral body margins. Therefore, bulging annulus can be distinguished by CT from herniated nucleus, which has a focal, usually posterolateral, protrusion of the disk margin. | [
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10,002,701 | Computed tomography as a definitive method for diagnosing gastrointestinal lipomas. | [
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10,002,702 | Evaluation of renal masses considered indeterminate on computed tomography. | [
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10,002,703 | Of 815 renal masses studied by computed tomography (CT), 60 did not fit the criteria for cyst or neoplasm and thus were called indeterminate. When artifacts were present, the likely diagnosis was a simple cyst; when no artifacts were present to explain atypical features in cyst-like masses, further investigation was necessary. Angiography was useful in only 16%, while ultrasound combined with cyst aspiration was diagnostic in 84%. All solid lesions required surgical investigation. Ultrasound with or without aspiration is recommended for all cyst-like renal masses thought to be indeterminate on CT. | [
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10,002,704 | Localization of functional adrenal tumors by computed tomography and venous sampling. | [
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10,002,705 | Fifty-eight patients with functional lesions of the adrenal gland underwent radiographic evaluation. Twenty-eight patients had primary aldosteronism (Conn syndrome), 20 had Cushing syndrome, and 10 had pheochromocytoma. Computed tomography (CT) correctly identified adrenal tumors in 11 (61%) of 18 patients with aldosteronomas, 6 of 6 patients with benign cortisol-producing adrenal tumors, and 5 (83%) of 6 patients with pheochromocytomas. No false-positive diagnoses were encountered among patients with adrenal adenomas. Bilateral adrenal hyperplasia appeared on CT scans as normal or prominent adrenal glands with a normal configuration; however, CT was not able to exclude the presence of small adenomas. Adrenal venous sampling was correct in each case, and reliably distinguished adrenal tumors from hyperplasia. Recurrent pheochromocytomas were the most difficult to localize on CT due to the surgical changes in the region of the adrenals and the frequent extra-adrenal locations. | [
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10,002,706 | Computed tomography as a supplement to urography in the evaluation of suspected neuroblastoma. | [
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10,002,707 | Eleven children in whom a retroperitoneal neuroblastoma was suspected on the basis of plain radiographic or urographic findings underwent computed tomography (CT). CT identified and localized a neurogenic tumor in eight patients. Calcifications were demonstrated by CT in six lesions, but by urography in only four. One neuroblastoma detected by CT was not seen on the urogram; in five patients greater extent of the tumor was defined by CT than by conventional radiologic procedures. In three patients CT excluded a neuroblastoma, but diagnosed other disorders (hepatic tumor, pancreatitis, and retrocaval ureter). Our results confirm that CT is a simple and accurate method for diagnosis, delineation of extent, or exclusion of neuroblastoma. | [
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10,002,708 | Computed tomographic evaluation of carcinoma of the cervix. | [
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10,002,709 | To assess the accuracy of computed tomography (CT) in staging advanced carcinoma of the cervix, 18 staging evaluations were performed in 16 patients with locally advanced (FIGO Stage IB-IVA) cervical carcinoma. CT staging results were compared with the results of clinical staging and postoperative staging. CT was accurate in 12/18 (66%) cases, clinical staging was accurate in 10/18 (55%) cases, and clinical staging with cystoscopy was accurate in 14/18 (78%) cases. CT staging failed to detect microscopic pelvic sidewall involvement and bladder involvement when there was no contrast material in the bladder. In the detection of para-aortic lymph node involvement by tumor, there were 12 true-negative, 4 true-positive, 1 false-positive, and 1 false-negative study (sensitivity = 80%, specificity = 92%). It is concluded that CT is equal in accuracy to other clinical staging techniques and offers the advantage of visualizing the tumor, which allows for more accurate determination of radiation portals. | [
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10,002,710 | Sonographic findings in four cases of hemangiopericytoma. Correlation with computed tomographic, angiographic, and pathologic findings. | [
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] |
10,002,711 | Four patients with hemangiopericytoma were examined with gray-scale sonography. Three of these patients were also evaluated by computed tomography (CT). The sonographic findings included well-defined, predominately cystic masses in two patients, a mixed solid and cystic mass in one, and a solid mass with shadowing in another. One hemangiopericytoma changed in sonographic appearance from cystic to solid following radiation. CT identified well-circumscribed masses in all three cases, but added little beyond what was seen on plain radiographs. Sonography may define the limits of a hemangiopericytoma, give information about the internal structure, and offer a way of following response to therapy. However, the sonographic features are varied and the often cystic nature of these tumors may be misleading. | [
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10,002,712 | The spectrum of sonographic findings in portal hypertension: a subject review and new observations. | [
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10,002,713 | Ultrasound demonstration of portosystemic collaterals in cirrhosis and portal hypertension. | [
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10,002,714 | Thickening of the gallbladder wall in acute hepatitis: ultrasound demonstration. | [
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10,002,715 | Thirty-six patients with acute hepatitis and 25 normal volunteers were examined by ultrasound to determine the thickness of the gallbladder wall. Liver enzymes were measured at the time of the examination in all patients. Ten were excluded, since they had other diseases which could lead to wall thickening. The mean thickness in 13 patients with SGOT and SGPT above 500 IU was 3.5 mm, compared to 2.6 mm in 13 patients with levels below 500 IU. This difference is statistically significant (P less than 0.01). Patients with acute hepatitis also had significantly thickened gallbladder walls compared to the volunteers (P less than 10(-8)). | [
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] |
10,002,716 | Observations on the distensibility of the common bile duct. | [
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10,002,717 | This series describes 9 patients in whom a rapid change in bile duct caliber was documented by ultrasonography, intravenous or direct cholangiography, or endoscopic retrograde cholangiopancreatography. Two major observations were made: (a) the capacity of the common duct to distend and collapse over a short period, and (b) discordant measurements of bile duct diameter on successive examinations with different modalities (i.e., ultrasonography followed by cholangiography). It is thought that these discrepant measurements can be explained by the ability of the common duct to distend rapidly in response to pathologic and physiologic fluctuations in biliary pressure. | [
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] |
10,002,718 | Infantile polycystic kidney disease: in utero sonographic diagnosis. | [
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] |
10,002,719 | Sonographic diagnosis of cerebroventricular hemorrhage in utero. | [
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10,002,720 | Sonographic spectrum of retroplacental hemorrhage. | [
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10,002,721 | Retroplacental hemorrhage (RPH), or abruptio placentae, usually occurs in the third trimester of pregnancy and may or may not be clinically significant. Sonographic criteria necessary for diagnosis of RPH include visualization of a linear or biconcave, and usually well-marginated mixed echogenic or anechoic region posterior to the placenta. Large areas of hemorrhage may cause bulging of the chorionic plate while small areas may be difficult to discern with routine scanning. Secondary signs of RPH include associated intraplacental anechoic regions secondary to bleeding or infarction and visualization of intra-amniotic hemorrhage. In this report, nine cases of pathologically confirmed RPH are reviewed. Also reviewed are normal and other pathological conditions of the placenta which may mimic RPH but should not be confused with the sonographic diagnosis. | [
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10,002,723 | 14C-lactose breath tests during pelvic radiotherapy: the effect of the amount of small bowel irradiated. | [
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10,002,724 | Thirty patients who were undergoing pelvic radiotherapy had 14C-lactose breath tests performed in the first and fifth weeks of treatment. In Group I (21 patients), a significant portion of the small intestine was irradiated, and in Group II (9 patients), only a small portion of the small intestine was irradiated. In Group I, the average reductions in the excretion of ingested 14C between the first- and fifth-week tests were 41.5% at 1/2 hour postingestion (p less than 0.05), and 21.8% at 1 hour postingestion (p less than 0.05). In Group II, the percentage reductions were 11.8% and 3.7% at 1/2 and 1 hour, respectively (p greater than 0.05). The data suggest that lactose malabsorption is a factor in the etiology of the nausea, vomiting, and diarrhea experienced by patients who are undergoing pelvic radiotherapy, and that the amount of bowel included in the treatment volume significantly influences the degree of malabsorption. | [
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10,002,725 | Methods for routine calibration of brachytherapy sources. | [
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] |
10,002,726 | Two types of routine geometry calibrators, the nuclear medicine dose calibrator and a Lucite jig holding a 30-ml external beam ion chamber with the source in a rigid geometry, were compared with open-air measurements for 137Cs, 192Ir, and 226Ra brachytherapy sources. The proximity of scattering surfaces in the second apparatus resulted in significant distortion of the buildup effect and deviation from the inverse square law (5% to 15%). For the dose calibrator, the response/Roentgen was found to be dependent not only on source energy, but on source capsule thickness as well. Approximately one half of the observed variation (27%) in calibration factors was accounted for by differences in filtration among sources. A mathematical logarithm that corrects for these geometric and filtration effects is presented. In addition, the activity assay procedure provided by the manufacturer of the dose calibrator is shown to be unsuitable for brachytherapy sources. Steps to overcome these problems are discussed. | [
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] |
10,002,727 | A dose table describing fractions of peripheral volume for 125I volume implants. | [
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10,002,728 | A dose table that provides the dose as a function of fractions of peripheral volume for 125I implants is presented. The table is based on seed distributions from 50 actual patient implants. Computer dosimetry was used to determine peripheral doses and dose ranges within implant volumes. The effects of seed distribution were also examined. The patient data and a study of computer-generated randomized seed coordinates within a given volume suggest that matched doses do not depend strongly on the exact position of each seed. The table provides the means for planning an implant to obtain a desired peripheral dose that can be directly compared with the postimplant computer dose calculation. | [
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] |
10,002,729 | Transrenal ureteral occlusion with a detachable balloon. | [
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10,002,730 | Transrenal ureteral occlusion using a detachable balloon was successfully employed to stop urinary flow in seven patients. The balloon was filled with low-viscosity silicone rubber and released in the distal ureter. Percutaneous nephrostomy provided external drainage. Indications were painful dysuria and large urinary fistulas in advanced pelvic malignancy. The method is preferable to ureteral embolization with tissue adhesive. | [
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10,002,731 | Transmission of gamma camera signals over long coaxial cables. | [
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10,002,732 | Saline-jet catheter deflection. A useful technique in cerebral catheter angiography. | [
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10,002,733 | Patient positioning for direct coronal computed tomography of the entire body. | [
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] |
10,002,734 | An optical density comparator. | [
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10,002,735 | New dilating needle for percutaneous angiography. | [
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10,002,736 | Delineation of masses identified on axial computed tomography. | [
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10,002,737 | Postoperative abscess drainage in patients with established sinus tracks or drains. | [
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10,002,738 | Treatment of aspergillosis. | [
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] |
10,002,739 | Double-contrast enema examination for detection of rectal carcinoma. | [
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10,002,740 | Hepatic artery embolization in the treatment of hepatic neoplasms. | [
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10,002,741 | The molecular nature of vascularly released cholecystokinin from the isolated perfused porcine duodenum. | [
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] |
10,002,742 | Using sequence-specific radioimmunoassays, the quantities and molecular nature of cholecystokinin (CCK) have been determined in extracts of porcine duodenal mucosa and in the vascular perfusate from the isolated porcine duodenum. The basal concentration of CCK in the perfusate was 84 pM equiv. CCK-8 (mean; range: 32-173 pM, n = 5). After intraluminal stimulation with amino acids, acidified fat emulsions and hydrochloric acid, the concentrations increased 2--5-fold. Both in the basal and stimulated state the concentrations of the related hormone, gastrin, were below 5 pM equiv. gastrin-17. CCK in the perfusate was concentrated by affinity-chromatography using antibodies directed against the bioactive C-terminus. Subsequent gel chromatography revealed a form with a size like or slightly larger than the C-terminal dodecapeptide (CCK-12), a predominant form resembling the C-terminal octapeptide (CCK-8), and a form resembling the C terminal tetrapeptide (CCK-4). The duodenal mucosa contained in addition CCK-33, -39 and CCK-peptides with further N-terminal extensions. The results suggest that small CCK peptides are the principal circulating forms, while CCK-33 and larger forms are biosynthetic precursors. | [
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10,002,743 | Pancreatic polypeptide is not involved in the regulation of the migrating motor complex in man. | [
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10,002,744 | The role of pancreatic polypeptide (PP) and motilin in the regulation of the migrating motor complex (MMC) was studied in normal subjects. Both plasma motilin and PP levels changed cyclically in the fasted state and were highest in the late phase II period preceding the activity front in the duodenum. A continental breakfast invariably disrupted the MMC and induced a fed pattern of motility. After the meal plasma motilin levels decreased whereas PP levels rose significantly. Infusion of pure porcine motilin during the fasted state induced an activity front and a rise in plasma PP levels. Infusion of bovine PP in doses producing plasma PP levels above the postprandial values neither induced an activity front nor prevented its occurrence. During PP infusion, however, plasma motilin levels were low, although the activity front was not inhibited. PP seems to have no clear role in the regulation of the motor component of the MMC of man. The role of motilin in the production of the activity front of the MMC is discussed. | [
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10,002,745 | [Monoamines and endogenous depression. Biochemical and pharmacological aspects]. | [
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10,002,746 | [Depression. Treatment]. | [
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10,002,747 | Left ventricular afterload and aortic input impedance: implications of pulsatile blood flow. | [
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10,002,749 | Aortic input impedance in cardiovascular disease. | [
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] |
10,002,750 | [Adam's syndrome or amniotic band disease]. | [
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10,002,751 | [Depression: definition, evaluation, classification]. | [
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10,002,752 | [Idiopathic spontaneous pneumothorax in young subjects. Clinical features, course and current treatment]. | [
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10,002,753 | [Ultrasound tomography of the cervical vessels]. | [
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10,002,754 | [Heredity and coronary atherosclerosis]. | [
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10,002,755 | [Drug-induced complications in ophthalmology]. | [
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10,002,756 | [Splenectomy in hematology]. | [
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10,002,757 | [Teratogenesis of behavior]. | [
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10,002,759 | Scattered electrons in microscopy and microanalysis. | [
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10,002,760 | The use of scattered electrons alone for direct imaging of biological specimens makes it possible to obtain structural information at atomic and near-atomic spatial resolutions of 0.3 to 0.5 nanometer. While this is not as good as the resolution possible with x-ray crystallography, such an approach provides structural information rapidly on individual macromolecules that have not been, and possibly cannot be, crystallized. Analysis of the spectrum of energies of scattered electrons and imaging of the latter with characteristic energy bands within the spectrum produces a powerful new technique of atomic microanalysis. This technique, which has a spatial resolution of about 0.5 nanometer and a minimum detection sensitivity of about 50 atoms of phosphorus, is especially useful for light atom analysis and appears to have applications in molecular biology, cell biology, histology, pathology, botany, and many other fields. | [
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10,002,762 | Pulmonary function changes after acute inhalation of chlorine gas. | [
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10,002,763 | Four young healthy adults were studied physiologically after accidental inhalation of chlorine gas. All patients were symptomatic with cough, tightness in the chest, and shortness of breath. All had restrictive ventilatory defect with impaired diffusing capacity. There was evidence of some obstruction in small airways. There was inconsistent evidence of obstruction in large airways. All lung function impairment was temporary and cleared entirely within one month. There was no residual lung damage. | [
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10,002,764 | Ventricular cardiac arrhythmias during anesthesia: feasibility of preoperative recognition. | [
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10,002,765 | We investigated the occurrence of anesthetic ventricular cardiac arrhythmia (CA) in 104 systemically healthy consecutive patients undergoing general anesthesia, to evaluate the possibility of recognizing preoperatively those patients prone to CA. In 19 (18%) patients, control strips taken before anesthesia showed CA. During anesthesia CA developed in 34 (33%), including 16 during induction, ten during endotracheal intubation, and eight during both events. Older patients had a higher incidence of CA than younger ones (P less than 0.01), and patients with preoperative CA showed a greater trend toward anesthetic CA. There were no anesthetic deaths in this group. Early detection and treatment avoided complications and sequelae of CA. A second anesthetist in the operating room, to monitor the cardiac rhythm during induction and intubation, possibly contributed to early detection of CA and is strongly recommended. | [
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10,002,766 | Rocky Mountain spotted fever in the United States: use of age-specific incidence to determine public health policy for a vector-borne disease. | [
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10,002,767 | The increasing national and regional incidence of Rocky Mountain spotted fever (RMSF) during the past two decades led us to look at nationally collected epidemiologic data on reported cases of RMSF for 1975 through 1978, paying special attention to age-specific incidence in the states where the disease is most common. The group aged 5 to 9 years was the cohort at highest risk of contracting RMSF, but it was the 40- to 59-year age group that had the highest case fatality rate (CFR), 11.3%. Control efforts should include an educational program aimed at school-aged children and their parents, as well as instructions for physicians (particularly family practitioners and internists) on the early recognition and proper treatment of this illness. | [
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10,002,768 | Declining mortality from hypertension and stroke. | [
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10,002,769 | Recorded mortality from hypertension and stroke has decreased dramatically in most countries during the last 50 to 75 years. The reported reduction in mortality may be due to changes in diagnostic fashions or coding procedures. However, the magnitude and consistency of the decline suggests the occurrence of a true decrease. The possibility that better treatment of hypertension is responsible for the reduction in mortality is attractive. However, based on temporal relationships, it seems more likely that much of the fall has resulted from an alteration in the determinants of blood pressure. Increasing use of antihypertensive drug therapy may account for an acceleration in the decline of stroke mortality during the last decade. If so, this represents one of the first tangible benefits of the massive public health efforts to detect and treat hypertension in the community. | [
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10,002,770 | The double contrast barium enema: why bother? | [
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10,002,771 | Despite a wealth of publications extolling the virtues of the double contrast barium enema (DCBE), it is clear that change is only gradual and that in many institutions the single contrast, full column barium enema (BE) is still the routine method of colonic investigation. Much of this may be due to a persistent belief, among the unconverted, that what was good enough yesterday is good enough today. There may also be a belief that an old dog cannot learn new tricks. At least, in many cases, he appears unwilling to try. These beliefs are all too often encouraged by a trickle of articles in the world literature that set out to refute the value of DCBE and thereby add fuel to the dying embers of "conservational" radiology. This article is an attempt to explode some of the persistent fantasies regarding DCBE by reviewing the literature, examining misconceptions, and, hopefully, laying them to rest in their graves--the position that overwhelming worldwide evidence as well as our own experience has assigned for them. I believe that there is little evidence to justify continued use of the barium enema as the standard technic for examining the colon. | [
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10,002,772 | Genetic misconceptions. | [
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10,002,773 | Reliability of histopathologic diagnosis of cervical intraepithelial neoplasia. | [
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10,002,774 | A study was designed to measure the inter-pathologist consistency of histopathologic diagnosis of cervical intraepithelial neoplasia (CIN) among four pathologists. Intra-pathologist reliability over time was also determined. Between-pathologist comparisons resulted in agreement only 50% of the time; however, 81% of pairs were within one CIN grade of each other. Seventy-one percent of first and second diagnoses of the same pathologist were identical and 93% of pairs were within one CIN grade. In seven cases, however, pairs of evaluations of the same slide were remarkably disparate, two considered normal and CIN III by the same pathologist at different times. The findings of this study, using the CIN grading system, are consistent with other studies using different classification schemes. Inconsistency of diagnoses and discrepancies between pathologists must be considered when conservative therapy is elected for a patient with cervical intraepithelial neoplasia. | [
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10,002,775 | Obstructive sleep apnea after lateral medullary syndrome. | [
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10,002,776 | Sleep apnea occurring in association with neurologic lesions is usually of the central type. We have described a patient in whom obstructive sleep apnea followed a lateral medullary syndrome. We hypothesize that the upper airway obstruction during sleep was due to weakness of the palatal and pharyngeal muscles resulting from the neurologic lesion. The patient initially had reduced respiratory center motor output (mouth occlusion pressure) which increased significantly after tracheostomy. We conclude that obstructive as well as central apnea may follow neurologic lesions. Each patient should be carefully evaluated to provide proper treatment. | [
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10,002,777 | Subdural empyema: an unusual complication of meningococcal meningitis. | [
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10,002,778 | Subdural empyema rarely is associated with bacterial meningitis in infants, particularly when the etiologic agent is Neisseria meningitidis. We have described a 3-month-old infant in whom relapse of meningitis due to Meningococcus group C was accompanied by a right-sided subdural empyema. Full recovery followed appropriate antimicrobial therapy and closed drainage. | [
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10,002,779 | Control of intrahepatic bleeding by superselective embolization of the middle hepatic artery. | [
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10,002,780 | Precordial honk in association with tricuspid valve prolapse. | [
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10,002,781 | Acute gouty arthritis presenting as polyarticular disease. | [
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] |
10,002,782 | Amphotericin B toxicity. | [
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] |
10,002,783 | "Early" carcinoma of the breast: evaluation of regional therapy and features influencing prognosis. | [
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10,002,784 | Between 1944 and 1969, 192 women with carcinoma of the breast were treated at The University of Texas System Cancer Center M. D. Anderson Hospital and Tumor Institute by standard radical mastectomy for small outer quadrant lesions and pathologically negative axillary lymph nodes. Twenty percent of these patients with "localized disease" eventually had disseminated breast cancer. Various patient, hormonal, genetic, and pathologic factors were found to have little influence on the prognosis. Patterns of metastatic disease revealed that these patients did not have a unique form of breast cancer, but apparently an earlier stage in the spectrum of advancing disease. The results of this study appear to represent the best that can be obtained with regional therapy for carcinoma of the breast and emphasize the need for reliable adjuvant therapy. | [
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10,002,785 | Long-range projection of average benefits under OASDI. | [
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] |
10,002,786 | Consumer price indexes for the elderly: British experience. | [
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10,002,787 | Investment policies and procedures of the social security trust funds. | [
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10,002,788 | In this article, the Deputy Commissioner of Social Security for Programs describes the policies and procedures that have been followed in investing the assets of the Social Security trust funds, explores possible alternative investment areas, and counters criticisms of investment results and maturity durations. The author's analysis shows that a departure from the current practice of investing most of the assets in long-term special issues of Federal debt would have adverse consequences for the private industrial economy, the Treasury Department, or the economy in general. He notes that, although the interest income of the trust funds in 1980 amounted to only 2.46 percent of the Social Security program's total income, the amount involved--$3.85 billion--was 1.5 times as large as total administrative expenses. | [
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10,002,789 | Economic forecasting: effect of errors on OASDI fund ratios. | [
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10,002,790 | A broad range of economic assumptions are used to project the future income and outgo of the Social Security system. The assumptions adopted by the Board of Trustees of the Old-Age and Survivors Insurance and Disability Insurance (OASDI) Trust Fund were rather consistently on the optimistic side of the actual experience that emerged. This article examines the experience of several key economic indicators during the 1970's. Acknowledging that forecasting such quantities is an inexact science at best, the authors present a formula for making estimates of OASDI fund ratios, given the necessary assumptions. The formula is used to project fund ratios from 1981 to 1986. It shows where the fund would stand if forecasting errors were to continue at the magnitudes experienced in 1970-76. | [
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] |
10,002,791 | A surgical technique for buttockectomy. | [
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10,002,792 | The buttockectomy is an en bloc resection of the gluteus maximus muscle and is usually performed for low-grade malignancy tumors of the buttocks that are encompassed by the muscle excised. After the incision of the skin widely around the tumor, skin flaps are created to expose the entire gluteus maximus muscle; the inferior rolled edge of the muscle is identified and traced laterally to its insertion on the iliotibial tract. For a left buttockectomy the operator proceeds clockwise, first releasing the insertions of the muscle from the iliotibial tract and greater trochanter and the origins from the crest of ilium and sacrum. For a right buttockectomy one proceeds in a counterclockwise fashion, again starting at the inferior aspect of the gluteus maximus muscle. Care must be taken to avoid damage to the sciatic nerve and to secure the inferior and superior gluteal vessels before they are transected. Suction drainage is secured to remove serum and ensure adherence of skin flaps to the resection site. If the skin closure is tight, retention sutures may be needed. | [
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10,002,793 | Nonsurgical factors important to the success of surgery for morbid obesity. | [
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10,002,794 | Procedure for infected femoral shunts. | [
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10,002,795 | Kidney size and outcome of reconstruction. | [
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10,002,796 | Colloid therapy for patients in traumatic shock. | [
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10,002,797 | Synchronous and metachronous carcinoma of the breast. | [
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10,002,798 | To determine the incidence of synchronous bilateral breast cancer, 100 women receiving their initial treatment for primary breast cancer prospectively underwent biopsy of the opposite breast. No patient had a clinically detectable abnormality in the contralateral breast, but 2% had unsuspected invasive ductal carcinomas. An additional 5% had premalignant lesions. To determine the incidence of the development of metachronous breast cancer, 153 women who underwent surgical treatment of primary breast cancer between 1955 and 1979 were followed from 2 months to 26 years, with an average of 3.6 years. During that time, 3.9% developed metachronous carcinomas of the contralateral breast. | [
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10,002,799 | Use of liver cytosol fractions in treatment of acute liver failure. | [
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