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10,002,800 | Quality of life assessment of patients in extremity sarcoma clinical trials. | [
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10,002,801 | Twenty-six patients with soft tissue sarcoma who participated in a randomized controlled clinical trial were studied to compare the impact of treatments on quality of life. Patients were treated with amputation plus chemotherapy or with limb-sparing surgery plus radiation therapy plus chemotherapy. After completion of treatments, when the patients' physical status had stabilized, a "Quality of Life Assessment" was administered. It consisted of the Psychosocial Adjustment to Illness Scale, the Sickness Impact Profile, the Barthel Function Scale, the Katz Activities of Daily Living Scale, nd an economic assessment. In addition, clinical assessments of mobility, pain, sexual relationships, and treatment trauma were obtained. Analysis of these assessments indicated that our hypothesis that limb-sparing surgery plus irradiation would provide improved quality of life when compared to amputation was not substantiated. | [
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] |
10,002,802 | Fatal pulmonary hemorrhage complicating Swan-Ganz catheterization. | [
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] |
10,002,803 | A case of fatal pulmonary hemorrhage secondary to catheterization with a balloon-tipped catheter is described, and the literature describing possible mechanisms for this complication is reviewed. A common denominator in patients suffering pulmonary hemorrhage is pulmonary hypertension. Recommendations for management of this complication are discussed. | [
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10,002,805 | The sequelae of deep vein thrombophlebitis, such as postphlebitic syndrome with or without ulcer, can be treated by direct surgery on the valve. The present surgical treatment of stasis ulcer includes removal of the incompetent communicating veins with excision of the ulcer and skin graft. If this operation is performed on patients who actually have deep venous incompetence, then a high incidence of reulceration and skin graft slough may be expected if there is no concommitant correction of deep venous incompetence. Experimental studies to restore venous valve function such as autogenous vein valve transplant, valvoplasty, homologous vein transplant, and synthetic valve procedures have been tried. It has been shown that with autogenous vein graft there are a lower incidence of thrombosis and a more effective restoration of valve competency than with other procedures. We operated on six patients utilizing an autogenous vein valve from the upper extremity to achieve hemodynamically functioning venous system of the lower extremity. Data on pre- and postoperative noninvasive evaluations and ascending and descending venography with the results of surgery will be discussed. | [
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10,002,806 | A reappraisal of the Mikulicz enterostomy in infants and children. | [
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10,002,807 | We performed the Mikulicz procedure in 46 pediatric patients. Thirty-five were high-risk patients, 20 of whom had necrotizing enterocolitis. High risk was defined by the presence of peritonitis, intestinal perforation, poorly demarcated intestinal gangrene, or severe associated systemic illness. The remaining 11 patients had the procedure performed for technical reasons, most commonly a discrepancy in the size of the proximal distal limb ratio greater than 4:1. The procedure consisted of intestinal resection with double-barreled enterostomy, crushing of the spur between stomas, and subsequent lateral closure of the enterostomy. The mortality rate of 30% was due to the underlying disease and in no instance was death caused by a complication of the procedure. Complications (13%) were stricture or prolapse of the stoma and wound infection. Subsequent enterostomy closure in 32 patients had no mortality rate and a 3% complication rate. Because the risk of fatal anastomotic leak and peritonitis is very low, we prefer the Mikulicz procedure to all other intestinal anastomotic techniques for high-risk pediatric patients. | [
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] |
10,002,808 | Congenital asplenia and anomalies of the gastrointestinal tract. | [
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10,002,809 | Congenital asplenia has been traditionally described in association with cardiopulmonary anomalies (Ivemark syndrome). A case of congenital asplenia with duplication of the hindgut and genitourinary tract, myelomeningocele, situs inversus abdominis, and imperforate anus generated interest in review of the gastrointestinal anomalies of 36 patients who died of the disease in Childrens Hospital of Los Angeles. A significant number were found to have situs inversus, malrotation of the bowel, esophageal varices, duplication and hypoplasia of the stomach, Hirschsprung's disease, imperforate anus, and duplication of the hindgut. These patients present with symptoms referable to their gastrointestinal anomalies and may not draw attention to the concomitant cardiopulmonary anomalies or to the absence of the spleen. It becomes important, therefore, to establish the presence of the spleen in infants suffering from various anomalies of the gastrointestinal tract because of the overwhelming septicemia that is known to complicate the clinical management of these patients. | [
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10,002,810 | Amebic peritonitis secondary to amebic liver abscess. | [
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10,002,811 | A series of 19 patients who had amebic peritonitis secondary to rupture of an amebic liver abscess is presented. This represents 2.4% of the patients treated for ALA during an 18.5-year period. Eighty-four percent were men and ages ranged from 6 to 70 years. Rupture occurred prior to admission in 17 patients. Abdominal pain and fever were the most common symptoms. Abdominal tenderness, liver enlargment, distention, and jaundice were the predominant physical findings. All patients underwent operation. Removal of necrotic and purulent material combined with wide drainage were carried out. In two patients with amebic cecal disease, intestinal bypass was also done. The mortality rate was 42%. It was significantly increased in patients over 50 years of age and in those in whom a correct preoperative diagnosis was not made. | [
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10,002,812 | Necrotizing fasciitis of perineum. | [
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10,002,813 | Twenty-eight patients with necrotizing fasciitis of the perineum were treated at the Mount Sinai Medical Center from 1971 to 1979. Ten of the 28 died of the disease, for a mortality rate of 36%. The mortality rate was even higher when the lesion was located in the perianal area and associated with diabetes mellitus and delayed surgical intervention. Necrotizing fasciitis is a rare disease that involves both superficial and deep fascia. It begins with fascial necrosis at onset and rapidly progresses to surrounding fascial planes, eventually involving overlying skin and underlying muscle. Evidence proves that it is not the result of abscess, but primarily originates from fascia and is devoid of frank pus in the well-formed pyogenic abscess cavity. If one observes dark brown necrotic turbid fluid and fails to see frank pus, the disease should be treated as necrotizing fasciitis by complete surgical removal of all necrotic tissue until the normal plane is reached. | [
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10,002,814 | Carnosine, histidine, and wound healing. | [
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10,002,815 | The relationships among carnosine, histidine, and wound healing were examined in rats fed either 100% or 50% of the reported histidine required for growth. Animals fed the adequate amount of histidine grew more rapidly and more efficiently than did animals on the low-histidine diet. When the rats reached the experimental weight range of 165 to 180 gm, they were anesthetized and wounded with back skin incision; a polyvinylchloride sponge was implanted under the skin before closure of the wound. Seven days after wounding, the histidine-sufficient animals had greater regenerative skin-breaking strength, collagen deposition, and tissue concentrations of free histidine and carnosine. Histidine and carnosine treatment (1 mg/100 gm body weight/day intraperitoneally) for 7 days after wounding increased tissue free-histidine concentrations and brought skin-breaking strength and collagen deposition up to "normal" in the animals on the low-histidine diet but did not further improve healing in the histidine-sufficient animals. Treatment with carnosine was similar, but slightly better than treatment with histidine. The results suggest an interaction between carnosine and stress and implicate carnosine as a histidine reserve in relation to histamine synthesis during trauma. | [
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10,002,816 | Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. | [
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10,002,817 | Persistent and recurrent hyperparathyroidism after previous unsuccessful surgery is a major problem for the patient and the physician. We have prospectively evaluated the ability of cine-esophagography, computed tomography, selective venous sampling for parathyroid hormone, and selective arteriography to preoperatively detect parathyroid tissue in 75 patients undergoing reoperation. The invasive studies were routinely and safely applied to all patients in an effort to determine their value. In 55% of studies performed, preoperative localization by selective venous sampling was consistent with the subsequent operative findings. Selective arteriography correctly localized abnormal parathyroid tissue in 49% of studies performed but was more specific than selective venous sampling. Cine-esophagography was not of help in localization but did demonstrate abnormalities of swallowing attributed to prior surgery. Computed tomography correctly localized 11% of patients studied. | [
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10,002,818 | Influence of failed vascular bypass procedures on conversion of below-knee to above-knee amputation levels. | [
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10,002,819 | From 1975 to 1980, 79 major limb amputations were performed from a group of 552 lower extremity vascular reconstructions with glutaraldehyde-stabilized umbilical vein grafts. All amputations were performed in instances in which limb salvage had been the indication for the attempted bypass (n = 520)--an incidence of 15.2%. Twelve of 51 below-knee (BK) amputations were converted to above-knee (AK) levels (crude failure rate, 23.5%). The highest crude failure rate occurred after failed bypass to the popliteal artery (33.3%); the lowest occurred after failed tibial bypass (16.7%), and the peroneal arteries were intermediate (22.2%). In addition to these 12, 28 primary AK amputations were performed. Excluding nine cases judged to require AK amputations before the attempted vascular reconstruction, success/failure rates for the entire series and each of the reconstruction types were calculated. Success, defined as a healed BK stump, occurred least after failed popliteal bypass, 44.5%, compared to 71.4% and 53.8% for the tibial and peroneal groups, respectively. Thus, failure of a popliteal bypass was more apt to lead to an AK amputation (56.5%) than failure of a distal bypass. In fact, tibial bypass failure leading to an AK stump occurred at a frequency (28.6%) almost similar to that obtained by other investigators when no previous bypass had been performed. Comparative cumulative graft patency and limb salvage rate data confirm the value of reconstructive vascular surgery, particularly in the peroneal group where negativism with regard to its clinical usefulness persists. With improved case selectivity and surgical expertise, increasing limb salvage rates can be secured while minimizing the definite morbidity of conversion of BK to AK amputation with failed vascular bypass. | [
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10,002,820 | Superficial thrombophlebitis of lower limbs. | [
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10,002,821 | In the absence of malignancy, thrombophlebitis of the lower limb is invariably associated with pre-existent varicose veins. Not until pulmonary embolism was reported to occur in superficial phlebitis did the clinician introduce anticoagulants and/or surgery in the management of this condition. In an effort to reach an effective approach to this problem, 1,000 consecutive cases of varicose veins of the lower limbs were reviewed. Of these patients, 779 were admitted for elective vein ligation and stripping and 221 presented with thrombophlebitis. The latter group was subdivided into four categories according to the mode of management: (1) local heat and anti-inflammatory agents, 60 cases; (2) anticoagulants, 22 cases; (3) phlebotomy, high saphenous ligation and anticoagulation, 4 cases; and (4) ligation and stripping, 135 cases. In category 4 the saphenous is removed in a routine fashion together wih all its tributaries. All perforators are exposed, evacuated of thrombus when present, and ligated subfascially. Thrombi were encountered in one or more perforating veins in 10 patients, but no pulmonary embolism was observed in this group of patients. All instances of documented pulmonary embolism (10 cases) occurred in category 1 with one fatality. The incidence of pulmonary embolism in the elective group of ligation and stripping (without phlebitis) was 0.5%. The data indicate that the surgical approach is safe and preferable to the other modalities for several reasons: (1) It eliminates the varicosities and the phlebitic process simultaneously, (2) a single hospitalization is necessary (cost effectiveness), and (3) no anticoagulants are needed. If, for any reason, surgery cannot be undertaken, then anticoagulants should be employed in an effort to avoid thromboembolism. | [
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10,002,822 | Gastroesophageal reflux in the severely retarded who vomit: criteria for and results of surgical intervention in twenty-two patients. | [
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10,002,823 | Forty-two severely retarded patients, ranging in age from 2 to 26 years, were referred for diagnostic evaluation because of chronic vomiting. The diagnosis of gastroesophageal reflux (GER) was made in 28 of the basis of reflux (grade III) on upper gastrointestinal series and the presence of esophagitis either grossly at endoscopy or on esophageal biopsy. Nissen fundoplication was performed in 22 because of the frequent occurrence of complications such as pneumonia, gastrointestinal blood loss, and malnutrition attributable to GER. The incidence of postoperative complications was 59%. However, during a mean follow-up period of 14.1 months, no further vomiting or gastrointestinal blood loss was encountered, and only one patient had a single episode of pneumonia. Weight gain in those who were malnourished was impressive. In addition, the already difficult care of the patients was greatly facilitated. Severely retarded patients with GER who suffer recurrent complications should be considered for Nissen fundoplication. | [
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10,002,824 | Differential patency and limb salvage for polytetrafluoroethylene and autogenous saphenous vein in severe lower extremity ischemia. | [
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10,002,825 | Polytetrafluoroethylene (PTFE) was compared to autogenous saphenous vein (ASV) in 133 femoropopliteal and femorotibial or peroneal bypass procedures performed in limb salvage during a 4-year period. PTFE was used as an alternative prosthesis in the absence of a suitable ASV. Sixty-nine femoropopliteal bypasses (FPBPs) were studied--36 with ASV and 33 with PTFE. Sixty-four femorotibial or peroneal bypasses were categorized as femoral distal bypasses (FDBPs)--34 with ASV and 30 with PTFE. With a 3-year clinical follow-up, cumulative function rate (CFR)--patency including thrombectomy--for FPBP with ASV was 65% as compared to 53% for PTFE (P greater than 0.05), whereas the limb salvage rate (LSR) was 75% with ASV and 56% for PTFE (P greater than 0.05). However for FDBP, the GFR was 55% for ASV and 7% for PTFE, whereas the LSR was 55% with ASV and 26% for PTFE. The cumulative patency rate (CPR)--initial thrombosis of a prosthesis as an endpoint--was not significantly (P greater than 0.05) different from CFR, suggesting that thrombectomy with or without distal anastamotic revision does not contribute to patency of the PTFE prosthesis in these limb salvage cases. PTFE was a suitable alternative to ASV for FPBP; however, PTFE is recommended for FDBP in selected cases only. | [
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] |
10,002,826 | Infant mortality in Texas. | [
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] |
10,002,827 | The evolution of myocardial preservation. | [
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10,002,828 | Reversible ischemic optic neuropathy in severe anemia. | [
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] |
10,002,829 | Texas physicians' attitudes toward death and dying. | [
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10,002,830 | Hospital staff privileges & the new Texas Medical Practice Act. | [
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10,002,831 | [Breeding and health impairment in dogs (author's transl)]. | [
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10,002,832 | [Laryngeal paralysis in Bouviers Belge des Flandres and breeding advice to prevent this condition (author's transl)]. | [
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10,002,833 | [Hereditary features of haemophilia and their consequences in dog-breeding (author's transl)]. | [
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10,002,834 | [Hip dysplasia in dogs (author's transl)]. | [
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10,002,835 | [Hereditary features of progressive retinal atrophy (PRA) and its consequences in dog-breeding (author's transl)]. | [
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10,002,836 | Progressive retinal atrophy (PRA) is a collective term comprising a group of hereditary degenerative lesions of the retina. A central and a generalized form can be differentiated. The central form (day blindness, hemeralopia) is characterized by accumulations of pigment in the layer of pigmented epithelium of the retina, atrophy of the cones and subsequent atrophy of the rods, eventually terminating in blindness. The generalized form (night blindness, nycteralopia) is marked by dysplasia of the rods and or cones, followed later by atrophy of the rods and cones, or it may be marked solely by atrophy of the rods and cones. Blindness occurs between the first and seventh years of life, varying with the breed and form. Hereditary transmission of the generalized form is recessive. Detection of patients is essential in controlling the disease. The number of carriers can be estimated on the basis of this detection, part of the carriers can be identified and the likelihood of an animal being a carrier can be calculated. The condition may be controlled by test matings to determine the genetic patterns of breeding dogs where progressive retinal atrophy is concerned. | [
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10,002,837 | [Mortality in sows caused by Treponema hyodysenteriae]. | [
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10,002,838 | Savoring success. An interview with Hunter B. Andrews, Democratic majority whip of the Virginia Senate. Interview by Chris Guy. | [
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10,002,839 | Foreperiod and visual stimulus intensity: a reappraisal. | [
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10,002,840 | Clinical applications of evoked potentials in neurology. | [
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10,002,841 | Problems in defining the normal limits of the visual evoked potential. | [
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] |
10,002,842 | Visual evoked potentials in aging of the brain. | [
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10,002,843 | Pattern- and flash-evoked potential changes in toxic (nutritional) optic neuropathy. | [
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10,002,844 | Evoked brain potential differentiation between geriatric subjects and chronic alcoholics with brain dysfunction. | [
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10,002,845 | Transient and steady state visual evoked potentials by checkerboard reversal pattern in renal diseases. | [
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10,002,846 | Visually evoked potentials in Friedreich's ataxia. | [
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] |
10,002,847 | Visual evoked potentials to pattern-reversal stimulation have been recorded in 45 patients with Friedreich's ataxia. In six patients, no response could be obtained because of optic atrophy; altogether, pathological results were found in 25 patients (55%). Normal latencies were recorded in 20 patients (45%). No statistically significant connection could be drawn between the result of the VEP testing and visual acuity, age, or onset and duration of sickness, but there was a strikingly familiar accumulation of results. There is a good conformity between our results and the incidence of optic atrophy in later stages of the disease as shown by pathological-anatomical and epidemiological studies. We have demonstrated that optic nerve lesions in Friedreich's ataxia are not as rare as is frequently assumed and that the VEP is a valuable tool for detecting them. On the other hand, unfortunately, the VEP is of no help in the differential diagnosis of Friedreich's ataxia versus multiple sclerosis. | [
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10,002,848 | Visual evoked potentials and alcohol-induced brain damage. | [
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10,002,849 | Brainstem auditory evoked potentials in clinical neurology. | [
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] |
10,002,850 | Correlation of brainstem evoked response with direct acoustic nerve potential. | [
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10,002,851 | Detection of acoustic neuromas with brainstem auditory evoked potentials: comparison between cochlear and retrocochlear abnormalities. | [
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10,002,852 | Contribution of brainstem auditory evoked potentials to diagnosis of tumors and vascular diseases. | [
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10,002,853 | Brainstem auditory evoked potentials and vertebral-basilar reversible ischemic attacks. | [
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10,002,854 | Clinical applications of brainstem auditory evoked potentials in comatose patients. | [
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10,002,855 | Value of the simultaneous recording of brain stem auditory evoked potentials, blink reflex, and short-latency somatosensory evoked potentials for the assessment of brainstem function in clinical neurology. | [
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10,002,856 | The visual evoked potential in hereditary optic atrophy. | [
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10,002,857 | Brainstem auditory evoked potentials in the neurologic clinic: improved stimulation and analysis methods. | [
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10,002,858 | Brainstem auditory evoked potentials in disorders of the primary sensory ganglion. | [
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10,002,859 | Quantitative survey of uremic brain dysfunction by auditory evoked potentials. | [
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] |
10,002,860 | The brainstem auditory evoked potential is a useful diagnostic tool in evaluating risk factors for hearing loss in neonatology. | [
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10,002,861 | Fourteen of 100 babies in an intensive care nursery showed abnormal BAEPs. An analysis of the clinical records identified nine risk factors. Neonatal asphyxia appeared to be associated with hearing loss only when repeated episodes of acidosis accompanied it. We conclude that the BAEPs can identify hard-of-hearing babies and estimate the type and amount of peripheral hearing loss. Prolonged perfusion of the cochlea with blood low in pH level may be the most common cause of hearing disorder in our group of nine risk factors. | [
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10,002,862 | Brainstem evoked responses in prematures. | [
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] |
10,002,863 | Right hemianacousia without language deficit. | [
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10,002,864 | Anosognosia with hemiplegia: auditory evoked potential studies. | [
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] |
10,002,865 | Long-latency event-related potentials in normal aging and dementia. | [
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10,002,866 | Evoked potentials in the assessment of brain function in senile dementia. | [
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10,002,867 | Recent progress in the understanding of subcortical somatosensory evoked potentials. | [
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10,002,868 | Short-latency somatosensory evoked potentials in man, monkey, cat, and rat: comparative latency analysis. | [
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10,002,869 | The visually evoked subcortical potential to flash stimulation in normal subjects and patients with lesions of the visual pathway. | [
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10,002,870 | Early somatosensory evoked potentials in thalamo-cortical lesions of the lemniscal pathways in humans. | [
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10,002,871 | Diagnostic significance of cortical somatosensory evoked potentials following trigeminal nerve stimulation. | [
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10,002,872 | Diagnostic value of segmental somatosensory evoked potentials in cases with chronic progressive para- or tetraspastic syndromes. | [
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] |
10,002,873 | Somatosensory evoked potentials before and after percutaneous thermocoagulation of the Gasserian ganglion for trigeminal neuralgia. | [
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10,002,874 | Intraoperative somatosensory evoked response monitoring during spinal cord surgery. | [
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10,002,875 | Evoked potentials as objective parameters for the analgesic response of weak analgesics. | [
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10,002,876 | Relationship between somatosensory evoked potential components and cutaneous pain threshold: effects of transcutaneous electrical nerve stimulation. | [
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10,002,877 | Human pain and evoked potentials: possible assessment of headache with endogenous brain potentials triggered by the R wave of EKG in pain patients. | [
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] |
10,002,878 | Visual and somesthetic potentials in neurolipidosis. | [
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10,002,879 | Intracerebral and scalp fields evoked by hemiretinal checkerboard reversal, and modeling of their dipole generators. | [
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10,002,880 | Pattern evoked potential diagnosis of multiple sclerosis: a comparison of various contrast stimuli. | [
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10,002,881 | 1. The transient and steady-state reversals seem to give equivalent information. 2. Random presentation of pattern reversals evokes the same response as conventional repetitive stimulation. Since random stimulation abolishes rhythmic activity, it is the most efficient stimulus form to generate a reversal response. 3. The pattern onset-offset stimulus is preferred for clinical application, since this stimulus is more efficient in evoking a contrast-evoked potential. 4. The absence of an evoked potential should never be used as a positive diagnostic criterion in MS. | [
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10,002,882 | Visual evoked potentials by central foveal and checkerboard reversal stimulation in multiple sclerosis. | [
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10,002,883 | In 200 patients with suspected MS, the diagnostic value of VEP elicited by checkerboard reversal and central foveal stimulation was compared. No significant difference was evident, but both methods overlap. The more stable checkerboard reversal stimulation should be preferred as a diagnostic method. Only in suspected MS with normal checkerboard responses, additional foveal responses may give supplementary information. Normal VEPs cannot exclude a prior retrobulbar neuritis. | [
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10,002,884 | A modification of the visual evoked response method involving small luminance decrements for the diagnosis of demyelinating diseases. | [
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10,002,885 | Delayed visual evoked potentials in multiple sclerosis: interpretation of VEP latencies for follow-up studies. | [
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10,002,886 | A comparison of clinical neuroophthalmological findings and pattern shift visual evoked potentials in multiple sclerosis. | [
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10,002,887 | Improved diagnostic yield in evaluation of multiple sclerosis using critical frequency of photic driving with pattern reversal-evoked potentials. | [
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10,002,888 | The pattern visual evoked potential in the clinical assessment of undiagnosed spinal cord disease. | [
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10,002,889 | Results of a prospective study on the value of combined visual, somatosensory, brainstem auditory evoked potentials and blink reflex measurements for disclosing subclinical lesions in suspected multiple sclerosis. | [
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10,002,890 | Brainstem auditory evoked potentials in reclassification of 143 MS patients. | [
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10,002,891 | Pattern-reversal visual evoked potentials in reclassification of 472 MS patients. | [
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10,002,892 | The pattern-reversal visual evoked potential in the clinical study of lesions of the optic chiasm and visual pathway. | [
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10,002,893 | Somatosensory evoked potentials following tibial nerve stimulation in multiple sclerosis and space-occupying spinal cord diseases. | [
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10,002,894 | Brainstem auditory evoked potentials in multiple sclerosis: influence of body temperature increase. | [
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10,002,895 | The value of a multimodal evoked potential approach in the diagnosis of multiple sclerosis. | [
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10,002,896 | Brainstem auditory evoked potentials: a comparative study of monaural versus binaural stimulation in the detection of multiple sclerosis. | [
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10,002,897 | The optically evoked blink reflex in the diagnosis of multiple sclerosis. | [
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10,002,898 | Changes in visual and short-latency somatosensory evoked potentials in patients with multiple sclerosis. | [
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10,002,899 | Exacerbation detection in multiple sclerosis by clinical and evoked potential techniques: a preliminary report. | [
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