chunk_id int64 1M 11.9M | document stringlengths 3 4.98k | embedding listlengths 384 384 |
|---|---|---|
10,000,300 | Process versus outcome in hypertension: a positive result. | [
-0.04383127763867378,
0.04815500229597092,
-0.04106908291578293,
-0.009108033031225204,
0.035125941038131714,
-0.0005697071319445968,
-0.015617910772562027,
0.045323096215724945,
0.009373624809086323,
-0.028714390471577644,
0.03471636027097702,
-0.007884226739406586,
0.0263974592089653,
0.... |
10,000,301 | We studied the association between the outcome of antihypertensive care and three items of that care among 230 hypertensive steelworkers who were referred to 83 physicians. The first item was the decision to treat some patients but not others: 63% of the patients were prescribed antihypertensive drugs and the mean decr... | [
-0.04024238511919975,
0.028344150632619858,
-0.0011535899247974157,
-0.010953821241855621,
-0.04999838024377823,
-0.009400914423167706,
-0.01275662798434496,
0.0912267193198204,
-0.03392240032553673,
-0.11581159383058548,
0.004283579997718334,
-0.014251134358346462,
0.03873274847865105,
-0... |
10,000,302 | The Canterbury Tales and cardiology. | [
0.04040350019931793,
0.06757901608943939,
-0.04322792962193489,
0.09301364421844482,
-0.0719134658575058,
0.03606567531824112,
-0.061910998076200485,
-0.03502301499247551,
-0.017418818548321724,
-0.045912329107522964,
-0.014773247763514519,
-0.011938545852899551,
-0.07366533577442169,
0.09... |
10,000,303 | The effects of nifedipine on myocardial blood flow and contraction during ischemia in the dog. | [
0.02724018320441246,
-0.05253627896308899,
0.03380540385842323,
0.06220421940088272,
0.00012688995047938079,
-0.023693503811955452,
0.008444664999842644,
0.045118700712919235,
0.0929064154624939,
-0.03460465744137764,
-0.07816437631845474,
-0.0077280886471271515,
0.0006273632170632482,
0.0... |
10,000,304 | Nifedipine has been proposed as an agent to preserve viability and function of ischemic myocardium. We studied 23 open-chest dogs that underwent carotid-to-left anterior coronary artery perfusion with flow probe and perfusion pressure monitoring. Segment length was measured with ultrasonic crystals in the ischemic and ... | [
0.058254681527614594,
-0.03330110013484955,
0.02949429303407669,
0.021454056724905968,
0.020960133522748947,
-0.053530603647232056,
-0.026720622554421425,
0.06509619206190109,
0.08026288449764252,
-0.03359229117631912,
-0.03876056149601936,
-0.012866630218923092,
0.010173174552619457,
0.09... |
10,000,305 | Determinants of myocardial hemorrhage after coronary reperfusion in the anesthetized dog. | [
0.021423617377877235,
-0.008817673660814762,
0.04425058886408806,
0.08861703425645828,
0.011100283823907375,
0.007293038070201874,
-0.05475693196058273,
0.054286275058984756,
0.10262159258127213,
-0.02194133959710598,
0.007756394799798727,
-0.02526457980275154,
0.00606617471203208,
0.15149... |
10,000,306 | Intramyocardial hemorrhage often occurs with reperfusion in experimental acute myocardial infarction and is thought to be associated with extension of necrosis. To determine if hemorrhage was associated with extension of necrosis, 20 anesthetized dogs were reperfused after 6 hours of circumflex coronary artery occlusio... | [
0.009734180755913258,
-0.06480888277292252,
0.02354712225496769,
0.06191304698586464,
0.022828396409749985,
-0.028696971014142036,
-0.07725223898887634,
0.12455909699201584,
0.1226266622543335,
0.027918649837374687,
0.012858720496296883,
-0.028396904468536377,
0.05522723123431206,
0.144866... |
10,000,307 | Thallium-201 kinetics in nonischemic canine myocardium. | [
0.004831176251173019,
-0.09951085597276688,
-0.005339446943253279,
0.06374035030603409,
-0.017931312322616577,
-0.1197805404663086,
-0.023380441591143608,
0.09613325446844101,
0.08298319578170776,
-0.048114337027072906,
0.056270781904459,
-0.0174846313893795,
0.07031378149986267,
0.0519947... |
10,000,308 | Effect of propranolol on myocardial perfusion images and exercise ejection fraction in men with coronary artery disease. | [
0.08269266784191132,
0.050972335040569305,
-0.0041342126205563545,
0.07658082991838455,
0.0352051667869091,
-0.0030159750021994114,
-0.03633435443043709,
0.05724184587597847,
0.06773632019758224,
0.0014443149557337165,
-0.05839264392852783,
0.034225206822156906,
-0.016698306426405907,
0.08... |
10,000,309 | Effect of the geometry of the left ventricle on the calculation of ejection fraction. | [
0.07483489066362381,
0.09120016545057297,
0.03514924272894859,
0.014675240032374859,
0.016134783625602722,
0.008823778480291367,
-0.04799184203147888,
0.025092188268899918,
0.05876733735203743,
-0.01430068351328373,
0.08232593536376953,
-0.04346291348338127,
-0.002638615667819977,
0.070248... |
10,000,310 | We used a cylindrical model for the left ventricle contracting both radially and longitudinally to show how the ejection fraction is related to different variables that describe the ventricular geometry. The relations during ventricular contraction between wall thickening, midwall radius shortening and longitudinal sho... | [
0.13549114763736725,
0.04787440970540047,
0.04237356409430504,
0.022385001182556152,
0.04379718750715256,
-0.004264668561518192,
-0.10735712200403214,
0.003353805746883154,
0.03303750604391098,
-0.10000745952129364,
0.035289160907268524,
-0.029674801975488663,
0.0208192877471447,
0.0693158... |
10,000,311 | Noninvasive determination of left ventricular end-systolic stress: validation of the method and initial application. | [
0.05501799285411835,
0.006070045288652182,
-0.03077015094459057,
0.04521475359797478,
0.11280368268489838,
-0.007918971590697765,
-0.07181024551391602,
-0.024234769865870476,
-0.0015360625693574548,
-0.08349564671516418,
-0.04256138950586319,
-0.037287820130586624,
-0.037997450679540634,
0... |
10,000,312 | Calcium-entry blockers in coronary artery disease: introduction. | [
-0.017163937911391258,
-0.01265977043658495,
0.00869239866733551,
0.06954082101583481,
-0.019973663613200188,
-0.050283562391996384,
-0.041064877063035965,
0.04426964744925499,
0.06368234008550644,
0.012761554680764675,
-0.000509565114043653,
-0.003216360229998827,
0.009509975090622902,
0.... |
10,000,313 | Effect of diltiazem on myocardial blood flow. | [
0.12142011523246765,
0.025336869060993195,
0.022982053458690643,
0.04953087493777275,
-0.010250401683151722,
-0.02866620384156704,
-0.02844283916056156,
0.09902579337358475,
0.06771142035722733,
-0.03167508915066719,
-0.01606970839202404,
-0.015043801628053188,
-0.00019242992857471108,
0.0... |
10,000,314 | We examined the effects of diltiazem on transmural myocardial blood in the presence of a flow-limiting stenosis and during acute total coronary artery occlusion in awake, chronically instrumented dogs. Regional myocardial perfusion was estimated with left atrial injections of 15-mu-diameter radionuclide labeled microsp... | [
0.09403085708618164,
-0.0035995778162032366,
0.03843192756175995,
0.08120148628950119,
0.021596776321530342,
-0.07524488866329193,
-0.0781092718243599,
0.06639767438173294,
0.08564824610948563,
-0.021367909386754036,
0.001675423700362444,
-0.04163065180182457,
-0.0031207099091261625,
0.074... |
10,000,315 | Beneficial effects of nifedipine on regional myocardial blood flow in patients with coronary artery disease. | [
0.06306072324514389,
-0.03318103402853012,
0.009406347759068012,
0.0224638469517231,
0.031092723831534386,
-0.055868666619062424,
-0.037293318659067154,
0.04200482740998268,
0.08122178167104721,
-0.09060195833444595,
-0.10075905919075012,
0.0169712845236063,
-0.024714702740311623,
0.085293... |
10,000,316 | Nifedipine inhibits the slow-channel calcium current, which plays a major role in vascular smooth-muscle contraction. However, the effect of nifedipine on regional myocardial blood flow (RMBF) in patients with coronary artery disease (CAD) is unknown. In 18 patients with chest pain syndromes, RMBF was determined with x... | [
0.05590701848268509,
-0.07339365035295486,
0.015706809237599373,
0.06291359663009644,
0.009086676873266697,
-0.06879376620054245,
-0.019824141636490822,
0.0642002671957016,
0.0824238732457161,
-0.04835202917456627,
-0.06108001619577408,
-0.019301796332001686,
-0.0019915939774364233,
0.1179... |
10,000,317 | On the significance of host factors that affect drug disposition. | [
0.11013050377368927,
0.0020270533859729767,
-0.03026055544614792,
0.027067644521594048,
0.06459544599056244,
0.0283715408295393,
0.04736647009849548,
0.1186741515994072,
0.017646407708525658,
-0.004896517377346754,
-0.016997601836919785,
0.05659399554133415,
0.03776097297668457,
0.07769668... |
10,000,318 | Reports on drug disposition in man often overemphasize statistical analyses or correlation coefficients at the expense of clear statements on the biological meaning of an experiment. Moreover, the results of many such studies are presented as though they were immutable. In reality, the levels of statistical significanc... | [
0.09350267797708511,
-0.0052997153252363205,
-0.03449918329715729,
0.04263981431722641,
0.06107698380947113,
0.01810503751039505,
0.024799838662147522,
0.13068170845508575,
0.059881195425987244,
0.022313132882118225,
-0.02926570363342762,
0.014038421213626862,
0.01204216293990612,
0.102922... |
10,000,319 | Heparin kinetics determined by three assay methods. | [
0.03868621215224266,
-0.08013863116502762,
-0.09149441123008728,
-0.04110945016145706,
0.06361397355794907,
0.0067009711638092995,
-0.049885094165802,
0.10708877444267273,
-0.02580210752785206,
0.018330877646803856,
-0.027007875964045525,
-0.026383478194475174,
-0.02855324000120163,
0.0488... |
10,000,320 | Heparin kinetics were determined in four normal subjects, each of whom received three different doses (25, 50, and 75 units/kg body weight) by intravenous injection. Multiple blood samples were collected after each dose and each plasma sample was assayed for heparin activity using three different assay methods. Two of ... | [
0.04056010767817497,
-0.07263902574777603,
-0.03958171233534813,
-0.05405447259545326,
0.0020484079141169786,
-0.014359820634126663,
-0.02348531410098076,
0.17785872519016266,
-0.0018881054129451513,
0.004984351806342602,
-0.014855042099952698,
-0.018727758899331093,
-0.011147573590278625,
... |
10,000,321 | Estimation of sympathetic activity in essential hypertension. | [
0.006102593149989843,
-0.04554365947842598,
0.010749077424407005,
0.08237043023109436,
0.07542213052511215,
-0.018259620293974876,
-0.003626827849075198,
-0.005073873791843653,
-0.04535764083266258,
-0.05194986239075661,
-0.013280153274536133,
-0.03744489327073097,
-0.012181298807263374,
0... |
10,000,322 | The estimation of sympathetic nervous activity by measurement of plasma norepinephrine (NE) concentration assumes a constant relation between this and the synaptic cleft concentration. This assumption would be incorrect if the clearance of plasma NE could be varied without affecting its removal from the synaptic cleft,... | [
0.047497354447841644,
-0.03047095239162445,
-0.013218102045357227,
0.014880727045238018,
-0.03217422962188721,
0.005569038446992636,
-0.06374399363994598,
0.029404539614915848,
0.08473462611436844,
-0.06783943623304367,
0.03166385367512703,
-0.032621219754219055,
-0.09184779226779938,
-0.0... |
10,000,323 | Sparteine metabolism in Canadian Caucasians. | [
0.07488848268985748,
0.03273686766624451,
-0.09564732015132904,
0.02985057793557644,
-0.10134532302618027,
-0.05900640785694122,
-0.006756753195077181,
-0.03284559026360512,
-0.011638202704489231,
-0.014461182057857513,
-0.03318685665726662,
-0.02717222459614277,
-0.05168986693024635,
-0.0... |
10,000,324 | The capacity for sparteine (SP) metabolism was determined in 48 Caucasian subjects by measuring amounts of drug and dehydrogenated metabolites in urine after an oral dose of SP sulfate. Three phenotypes were recognized and were assumed to represent individuals homozygous for poor SP oxidation (group III) and those hete... | [
0.0034173030871897936,
-0.07569176703691483,
-0.017444804310798645,
-0.02404969558119774,
-0.055640850216150284,
-0.04935787618160248,
-0.020391523838043213,
0.05488179624080658,
-0.008075484074652195,
-0.02570072002708912,
-0.033990729600191116,
0.01645715907216072,
-0.05672426149249077,
... |
10,000,325 | Sex differences in absorption kinetics of sodium salicylate. | [
0.028006184846162796,
-0.10409470647573471,
0.017811661586165428,
0.05765582621097565,
0.06601575016975403,
-0.020941143855452538,
0.057602617889642715,
-0.0009739008964970708,
-0.018750950694084167,
-0.04173186048865318,
-0.009144841693341732,
0.0019975160248577595,
0.016658850014209747,
... |
10,000,326 | Sodium salicylate in aqueous solution (9 mg/kg) was given by oral and intravenous routes to normal male and female subjects. Because the bioavailability of salicylate was complete, salicylate was given orally in all subsequent experiments. There were sex differences in time required to attain peak salicylate concentrat... | [
0.01830894500017166,
-0.0485442653298378,
-0.059055134654045105,
0.03373873233795166,
0.009885264560580254,
0.032624248415231705,
0.009273500181734562,
0.09154167771339417,
0.03687233850359917,
-0.0703083798289299,
-0.03892682120203972,
0.0331784151494503,
-0.005510907154530287,
0.11166600... |
10,000,327 | Antipyrine disposition in milk and saliva of lactating women. | [
0.05455509573221207,
-0.11378717422485352,
-0.007735937833786011,
-0.0038014925085008144,
-0.008134125731885433,
0.02396846003830433,
0.0299702025949955,
0.10498430579900742,
-0.08062989264726639,
-0.007685225922614336,
-0.018907878547906876,
-0.056029658764600754,
-0.051590245217084885,
0... |
10,000,328 | Widely used to study hepatic drug metabolism, antipyrine rapidly distributes in total body water. Antipyrine distribution was studied in seven lactating women. Duration of lactation ranged from 2 to 19 mo. In all subjects the drug was rapidly absorbed; in five women peak concentrations were attained in milk and saliva ... | [
0.07111351191997528,
-0.0792829692363739,
0.019118288531899452,
0.004913571756333113,
0.0006474685505963862,
-0.039084915071725845,
-0.03567488491535187,
0.1420534998178482,
-0.05110988765954971,
-0.007108279969543219,
-0.011260556057095528,
-0.022837355732917786,
-0.013486078009009361,
0.... |
10,000,329 | Age and renal clearance of cimetidine. | [
0.03518608212471008,
-0.030416570603847504,
-0.02571813203394413,
-0.03287476301193237,
-0.09508612751960754,
-0.037998709827661514,
-0.05021597072482109,
0.1485683172941208,
-0.009644229896366596,
-0.04952508211135864,
0.01814327947795391,
-0.02929476834833622,
0.020744893699884415,
0.076... |
10,000,330 | In 35 patients (ages 20 to 86 yr) receiving cimetidine therapeutically two serum samples and all urine formed in the interim were collected for analysis of cimetidine by high-pressure liquid chromatography and for creatinine. Cimetidine clearance decreased with age. The extrapolated 6-hr serum concentration of cimetidi... | [
0.016379963606595993,
-0.023478878661990166,
-0.044178809970617294,
0.031154442578554153,
-0.016351625323295593,
0.011720745824277401,
-0.036569397896528244,
0.1621646285057068,
0.029306700453162193,
-0.03321528434753418,
0.007474638521671295,
0.018223054707050323,
0.07060717791318893,
0.1... |
10,000,331 | Altered hydroxydesipramine concentrations in elderly depressed patients. | [
0.035440292209386826,
-0.032057229429483414,
-0.03266090154647827,
0.057721033692359924,
-0.04624628648161888,
0.06654190272092819,
-0.0017013124888762832,
0.10349000245332718,
0.0446799173951149,
-0.10186448693275452,
-0.05172256380319595,
0.02740701101720333,
0.06412217020988464,
0.01120... |
10,000,332 | Recent reports demonstrate that hydroxy metabolites of desipramine (DMI) have pharmacologic activity and do not just produce side effects. In patients treated with DMI, we determined the ratio of 2-hydroxydesipramine (2-OH-DMI) to drug at steady state. The ratios in the elderly patients were higher than in younger pati... | [
-0.002319695893675089,
-0.07901415228843689,
0.030859172344207764,
-0.059711188077926636,
-0.061348218470811844,
-0.061799634248018265,
-0.036305006593465805,
0.1545097827911377,
-0.012823227792978287,
-0.061268046498298645,
-0.04773567616939545,
0.01130565907806158,
0.01629440300166607,
0... |
10,000,333 | Amiloride in primary hyperaldosteronism. | [
-0.04994921758770943,
-0.004144558683037758,
-0.0075586405582726,
-0.00011890364112332463,
0.03414138779044151,
-0.06934154778718948,
0.008665911853313446,
0.06872007995843887,
0.0282109547406435,
-0.049586694687604904,
0.07201271504163742,
-0.012365357019007206,
0.022914014756679535,
0.00... |
10,000,334 | Amiloride is a potassium-sparing diuretic used in spontaneous and diuretic-induced hypokalemia. The effect of amiloride was studied prospectively in 12 patients with primary hyperaldosteronism. Four patients had unilateral adrenal adenomas and eight had bilateral adrenal hyperplasia. All patients were hypertensive and ... | [
-0.05466829985380173,
0.04557553306221962,
0.04319239780306816,
0.016970042139291763,
-0.028978653252124786,
-0.0452909991145134,
0.014105767011642456,
0.02386079542338848,
0.03207596018910408,
-0.0364784337580204,
0.06216476112604141,
-0.012919623404741287,
0.0009122974588535726,
-0.02442... |
10,000,335 | Alpha1-acid glycoprotein concentration and protein binding in trauma. | [
0.036825791001319885,
-0.08631110191345215,
-0.019409548491239548,
0.052913568913936615,
0.05879969894886017,
0.05649228021502495,
0.05395729839801788,
0.09428465366363525,
0.03152279183268547,
-0.014544474892318249,
0.0060083214193582535,
0.09119405597448349,
-0.06888183206319809,
0.10490... |
10,000,336 | Alpha 1-Acid glycoprotein (AAG) concentrations were measured every 2 to 3 days in eight trauma patients and seven healthy subjects for approximately 3 wk. Mean AAG concentrations in the trauma patients rose from 100 mg/dl to a peak value of 243 mg/dl at 10 to 14 days. AAG levels averaged more than 200 mg/dl at 15 to 21... | [
0.06659968197345734,
-0.12107597291469574,
-0.02138330601155758,
0.09131653606891632,
0.010551733896136284,
0.06669225543737411,
0.09650799632072449,
0.1524192988872528,
0.05601309984922409,
-0.037432968616485596,
0.0017415250185877085,
0.0639859065413475,
-0.0460229329764843,
0.0737261474... |
10,000,337 | Coffee and caffeine and alcohol effects on psychomotor function. | [
-0.006302343215793371,
-0.011611993424594402,
0.024095548316836357,
0.10484813898801804,
-0.014136453159153461,
0.09680866450071335,
0.03685992956161499,
-0.008332837373018265,
0.05928012356162071,
-0.003956938628107309,
-0.03418859466910362,
-0.02273852936923504,
-0.04047643393278122,
0.0... |
10,000,338 | Interactions of alcohol and caffeine were studied in two double-blind and crossover trials in which several psychophysiologic functions and subjective effects were measured in healthy men. The effects of alcohol (1 gm/kg) with and without caffeine (200 or 500 mg) were measured in 10 subjects. Two doses (0.7 or 1.5 gm/k... | [
0.042983394116163254,
-0.035263270139694214,
0.019052738323807716,
0.13788269460201263,
0.019833508878946304,
0.084259033203125,
0.0035980604588985443,
-0.00440858444198966,
0.04497700557112694,
-0.02522607520222664,
-0.027217114344239235,
-0.04070327430963516,
-0.020554810762405396,
0.025... |
10,000,339 | Plasma protein binding of phencyclidine. | [
0.014834149740636349,
-0.08816844969987869,
-0.12138514220714569,
0.02734476886689663,
0.0021356723736971617,
0.04312189295887947,
0.04070085659623146,
0.08034910261631012,
0.08932133764028549,
0.003140747547149658,
0.0665925070643425,
-0.006122755818068981,
0.012125994078814983,
0.1375196... |
10,000,340 | In healthy male subjects (n = 12) phencyclidine (PCP) free fraction was 22.0 +/- 2.8 % (mean +/- SD). In male patients with mild to moderate alcoholic liver disease (n = 16) free fraction (23.0 +/- 3.4%) was of the same order as in healthy subjects although age and the concentrations of albumin, bilirubin, and high-den... | [
0.05870329588651657,
-0.05522994324564934,
-0.07816068828105927,
0.035223741084337234,
0.02245524898171425,
0.024007195606827736,
0.007144636940211058,
0.12320876121520996,
0.002945267129689455,
-0.055961351841688156,
0.014400826767086983,
0.011231636628508568,
-0.05913855507969856,
-0.001... |
10,000,341 | Metoprolol withdrawal phenomena: mechanism and prevention. | [
0.026369769126176834,
-0.017030727118253708,
0.011021129786968231,
0.0594775415956974,
0.01492772251367569,
0.0053349630907177925,
0.06421408802270889,
0.09267919510602951,
0.10114891827106476,
-0.06592360138893127,
-0.06679738312959671,
0.0662805363535881,
0.01238139346241951,
-0.04454833... |
10,000,342 | Eight patients taking metoprolol (300 mg/day) for essential hypertension were studied after abrupt withdrawal and placebo replacement of the drug. A 52% average rebound increase in cardiac chronotropic sensitivity to isoproterenol and 15% rebound rise in resting heart rate occurred in all patients between 2 to 8 days a... | [
-0.0040967692621052265,
-0.05090605095028877,
-0.012016791850328445,
0.05752438306808472,
0.054786212742328644,
-0.0007048097322694957,
-0.03308498486876488,
0.0894586518406868,
0.07914095371961594,
-0.09103880077600479,
-0.03163658827543259,
-0.001320029841735959,
-0.01827121712267399,
0.... |
10,000,343 | Cimetidine dynamics after single intravenous doses. | [
0.0468817837536335,
-0.09558446705341339,
-0.030169356614351273,
0.034664954990148544,
-0.047283291816711426,
-0.07054924964904785,
-0.04048217833042145,
0.13116011023521423,
0.08318538963794708,
-0.04759136587381363,
0.04917416721582413,
-0.0016796141862869263,
0.05484933778643608,
0.0776... |
10,000,344 | Cimetidine dynamics were studied in nine multiple-trauma patients. Mean elimination half-life was 2.27 hr, mean volume of the central compartment was 0.29 l/kg, mean volume at steady state averaged 0.90 l/kg, and mean total body clearance was 9.02 ml/min/kg. After intravenous cimetidine, drug concentrated in gastric fl... | [
0.08378014713525772,
-0.07083527743816376,
-0.048542167991399765,
-0.007794523146003485,
-0.0005838297074660659,
0.003657989203929901,
-0.021476855501532555,
0.161154642701149,
0.09529201686382294,
-0.07247097045183182,
0.01414522621780634,
-0.003714757738634944,
0.021313467994332314,
0.11... |
10,000,345 | Intravenous pirbuterol. | [
0.0231225173920393,
0.019962310791015625,
-0.03397555276751518,
0.005111394915729761,
-0.041130535304546356,
-0.021483754739165306,
-0.029740292578935623,
0.11082883924245834,
0.04649464413523674,
-0.03610437735915184,
0.016091657802462578,
0.05958600714802742,
0.02426096424460411,
0.02858... |
10,000,346 | Pirbuterol was given intravenously to nine normal men to determine the hemodynamic effects of intravenous injection of this rather selective beta 2-adrenoceptor agonist. Pirbuterol induced marked improvement of the echocardiographic (percent change in the dimension of the minor axis of the left ventricle during systole... | [
0.054264653474092484,
-0.030962621793150902,
-0.017653753980994225,
0.02476532571017742,
-0.024621933698654175,
0.045564062893390656,
-0.1037701740860939,
0.051634371280670166,
0.06707420945167542,
-0.047078683972358704,
-0.00982007198035717,
0.0009419595589861274,
-0.0021729744039475918,
... |
10,000,347 | Cefsulodin kinetics in healthy subjects after intramuscular and intravenous injection. | [
0.07482344657182693,
-0.12168250232934952,
-0.03679757937788963,
-0.019789274781942368,
-0.012436009012162685,
-0.023670697584748268,
0.0006645164103247225,
0.10909776389598846,
0.09560273587703705,
-0.03924151882529259,
0.07368098944425583,
-0.05263437703251839,
0.050659723579883575,
0.05... |
10,000,348 | We evaluated cefsulodin kinetics in normal subjects after 250-, 500-, and 1,000-mg, intramuscular injections and 500-, 1,000-, and 2,000-mg 30-min intravenous infusions. Twelve plasma and four urine samples were collected in the first 12 and 24 hr. Plasma samples were analyzed by a new, highly precise high-performance ... | [
0.0038304077461361885,
-0.09329626709222794,
-0.03024277836084366,
-0.04725243151187897,
-0.019512027502059937,
-0.030513374134898186,
-0.04989171773195267,
0.21689581871032715,
0.09514059871435165,
-0.020650051534175873,
0.03024275228381157,
-0.09818565100431442,
-0.009165365248918533,
0.... |
10,000,349 | Anesthesia and the obese patient. | [
0.01277080737054348,
0.06825889647006989,
-0.055211134254932404,
0.08871517330408096,
-0.06667150557041168,
-0.0035880280192941427,
0.053991060703992844,
0.03459964692592621,
0.023465387523174286,
-0.010949328541755676,
-0.043313030153512955,
0.04294326901435852,
-0.020515212789177895,
0.0... |
10,000,350 | Definitions and risks of obesity. | [
-0.0006749370950274169,
0.058940302580595016,
-0.05966571718454361,
0.07561177015304565,
-0.0030609488021582365,
0.08240653574466705,
0.043389637023210526,
0.004781757015734911,
-0.07256627827882767,
0.014443252235651016,
0.04008369892835617,
-0.025448564440011978,
0.024816635996103287,
-0... |
10,000,351 | Nursing care for the severely obese patient. | [
0.015747936442494392,
0.016228334978222847,
-0.03629421442747116,
0.09524007141590118,
-0.06586521118879318,
0.005945354234427214,
0.0010537676280364394,
-0.01665344275534153,
-0.05907655134797096,
-0.07508164644241333,
-0.03672301396727562,
0.01051747240126133,
-0.06727876514196396,
0.029... |
10,000,352 | Care of the morbidly obese person (BMI greater than or equal to 30) during the perioperative period is specific and differs from routine nursing care. Effective communication, preplanning, and psychologic and physiologic assessment, with appropriate intervention (pulmonary and circulatory), result in positive care outc... | [
-0.0290265791118145,
-0.02080852910876274,
-0.04070119187235832,
0.08941413462162018,
-0.009113387204706669,
0.03786954656243324,
0.007922657765448093,
0.05717189610004425,
0.03367551788687706,
-0.03893278166651726,
-0.032824356108903885,
-0.011270225048065186,
0.015191293321549892,
0.0440... |
10,000,353 | Pulmonary and cardiovascular derangements in the obese patient. | [
0.010148252360522747,
0.09542862325906754,
-0.004983604419976473,
0.04876064881682396,
-0.01098339632153511,
-0.019223719835281372,
0.04648943245410919,
-0.0015216429019346833,
-0.037383776158094406,
-0.02175530605018139,
0.028996732085943222,
-0.02745681442320347,
0.009090883657336235,
0.... |
10,000,354 | The liver in obesity. | [
0.04843955859541893,
0.0421912781894207,
-0.07944973558187485,
0.08580360561609268,
-0.024098914116621017,
0.007448667194694281,
0.0018215409945696592,
0.0495574064552784,
-0.07193004339933395,
-0.015777744352817535,
0.008542491123080254,
-0.02276696264743805,
-0.013742770999670029,
-0.015... |
10,000,355 | Biochemical and biotransformation alterations in obesity. | [
0.023565195500850677,
0.032184287905693054,
-0.07507248222827911,
0.08309978246688843,
0.009367087855935097,
0.07701440900564194,
0.002456980524584651,
-0.017651299014687538,
-0.013865004293620586,
-0.016040120273828506,
-0.06772082298994064,
-0.06082471087574959,
-0.0562593974173069,
-0.0... |
10,000,356 | Anesthetic management of the morbidly obese patient. | [
0.026170983910560608,
0.05577101185917854,
-0.04526901617646217,
0.07512975484132767,
-0.1240738108754158,
-0.00009556940494803712,
0.04125404730439186,
0.032719992101192474,
-0.007960251532495022,
0.0011350932763889432,
-0.06978032737970352,
-0.014286351390182972,
-0.00013636035146191716,
... |
10,000,357 | Anesthetic management should concentrate on various aspects of pre-, intra-, and postoperative care. Particular laboratory studies, such as arterial blood gases, electrocardiogram, selected pulmonary function tests (e.g., ERV), and serum hepatic profile, can be quite useful. Preoperatively, technical difficulties (intr... | [
0.01605946570634842,
0.032624367624521255,
-0.06275610625743866,
0.007975639775395393,
-0.07763152569532394,
-0.008831765502691269,
-0.018785541877150536,
0.09229909628629684,
0.029726199805736542,
0.012069943360984325,
-0.02494688704609871,
0.02069154754281044,
-0.009641310200095177,
0.02... |
10,000,358 | Surgical treatment of morbid obesity. | [
0.030357444658875465,
0.06823999434709549,
0.006945242173969746,
0.0691622942686081,
-0.07750329375267029,
-0.021172285079956055,
0.019949128851294518,
0.014266366139054298,
-0.05220521241426468,
-0.0008284174255095422,
-0.02853359654545784,
0.015900593250989914,
-0.0007650302723050117,
0.... |
10,000,359 | Effects of massive weight loss. | [
0.037282004952430725,
0.09141793847084045,
0.03197858855128288,
0.1089363545179367,
0.004326478578150272,
0.05274925380945206,
0.01350859459489584,
0.07043348252773285,
-0.04350168630480766,
-0.012356091290712357,
-0.03293929621577263,
0.053999632596969604,
-0.008025006391108036,
-0.041927... |
10,000,360 | Sphincter of Oddi motor activity: a comparison between patients with common bile duct stones and controls. | [
0.03233489394187927,
-0.17201930284500122,
0.024589363485574722,
-0.0011215618578717113,
-0.08429916948080063,
-0.03558487072587013,
0.0009088453371077776,
-0.0007768902578391135,
-0.007409884128719568,
-0.025337114930152893,
0.0934806540608406,
0.00013521502842195332,
0.009320909157395363,
... |
10,000,361 | A case of primary sclerosing cholangitis in childhood. | [
0.020332131534814835,
-0.07325764745473862,
0.02921595424413681,
0.05724779888987541,
-0.02702455408871174,
0.013214359059929848,
0.002256599720567465,
0.05493729189038277,
-0.02874099835753441,
0.005127157084643841,
0.010400724597275257,
0.010800984688103199,
0.0346543975174427,
0.0489225... |
10,000,362 | Spontaneous bacterial peritonitis due to Clostridium tertium. | [
0.036380261182785034,
-0.019770652055740356,
-0.0035041349474340677,
0.011968986131250858,
-0.040780000388622284,
-0.0857522040605545,
-0.02742994949221611,
0.08651158213615417,
0.07919593900442123,
-0.0775560513138771,
-0.0005685508949682117,
-0.00693698413670063,
0.027121329680085182,
0.... |
10,000,363 | Mallory-Weiss tear complicating upper endoscopy: case reports and review of the literature. | [
-0.03630105033516884,
-0.011421358212828636,
0.05437759310007095,
0.04094822332262993,
-0.03462463244795799,
-0.011519303545355797,
-0.0394493006169796,
0.09805141389369965,
-0.06298599392175674,
0.0038080851081758738,
-0.011619673110544682,
0.059775348752737045,
-0.031644534319639206,
0.0... |
10,000,364 | Lymphomas involving the gastrointestinal tract. | [
0.06518843024969101,
0.007866722531616688,
-0.014069106429815292,
0.011622949503362179,
-0.03521030396223068,
-0.01149808056652546,
0.022044386714696884,
0.017594655975699425,
0.061722878366708755,
-0.06971922516822815,
-0.022856377065181732,
0.08892624080181122,
0.012603353708982468,
-0.0... |
10,000,365 | Hepatic transport kinetics: can traditional models open the black box? | [
0.04144234210252762,
-0.12183158844709396,
-0.02566022425889969,
0.012360191904008389,
-0.02056860737502575,
-0.032966192811727524,
-0.021982284262776375,
0.06939882040023804,
-0.03062564507126808,
-0.014411619864404202,
0.012455934658646584,
0.008819598704576492,
-0.039570946246385574,
0.... |
10,000,366 | Is epigastric tenderness a sign of peptic ulcer disease? | [
0.015000262297689915,
-0.040976352989673615,
-0.07903330028057098,
0.1096210703253746,
-0.0366254560649395,
0.00003648249548859894,
0.028891926631331444,
0.11143779009580612,
0.0477740652859211,
-0.0799463614821434,
0.03153057396411896,
-0.015422102063894272,
0.0036424885038286448,
-0.0044... |
10,000,367 | Smoking and ulcer healing. | [
0.007943892851471901,
0.05915331095457077,
0.0342344269156456,
0.0935746431350708,
-0.004297833889722824,
0.027540549635887146,
0.01770692691206932,
0.03946520388126373,
0.01322538685053587,
-0.08136461675167084,
-0.005955420900136232,
0.045147016644477844,
-0.01655549928545952,
-0.0219809... |
10,000,368 | Alcohol hepatitis therapy. | [
0.0431094691157341,
-0.004220024682581425,
-0.048220958560705185,
-0.016882680356502533,
-0.0004762304888572544,
0.04832121357321739,
-0.022948015481233597,
0.08335472643375397,
-0.023732617497444153,
-0.017635108903050423,
0.023515820503234863,
0.006129260640591383,
-0.056632883846759796,
... |
10,000,369 | Hyperamylasemia in acute alcoholism. | [
0.044067297130823135,
-0.03825104609131813,
-0.03514253348112106,
0.08339650183916092,
-0.0160137340426445,
-0.035162586718797684,
-0.0013284320011734962,
-0.004421060439199209,
-0.01563286781311035,
-0.013404433615505695,
-0.05119618400931358,
0.019433796405792236,
-0.06587835401296616,
0... |
10,000,370 | Acid output and ulcer healing. | [
0.009399209171533585,
-0.008700136095285416,
0.006116113159805536,
0.1120624989271164,
0.0092208506539464,
0.050844572484493256,
0.010860869660973549,
0.07294942438602448,
-0.015597661025822163,
-0.1155896708369255,
0.01701362617313862,
0.010155575349926949,
0.01258829329162836,
-0.0052715... |
10,000,371 | Pepsinogens I and II: purification from gastric mucosa and radioimmunoassay in serum. | [
0.09805349260568619,
-0.020051557570695877,
-0.06911012530326843,
0.03238299489021301,
0.04776256904006004,
-0.006098204292356968,
0.17297188937664032,
0.05514507740736008,
0.015451280400156975,
-0.0304303839802742,
0.003502294421195984,
-0.0014441241510212421,
0.01798420026898384,
0.05563... |
10,000,372 | Pepsinogen I and pepsinogen II were purified from gastric mucosa and used to develop a radioimmunoassay for pepsinogen II and an improved radioimmunoassay for pepsinogen I. Each immunochemically homogeneous preparation contained only its characteristic components by radioelectophoretic analysis, and migrated as a singl... | [
0.10680646449327469,
-0.06518880277872086,
-0.07707428187131882,
0.03180056810379028,
-0.005852825008332729,
-0.024808768182992935,
0.11254996061325073,
0.11101507395505905,
-0.0025236126966774464,
-0.013690628111362457,
-0.007426283322274685,
-0.01940106973052025,
0.04609345272183418,
0.0... |
10,000,373 | Estrogen predisposes to cholecystectomy but not to stones. | [
0.0496751107275486,
-0.051700953394174576,
0.015889158472418785,
0.04235878586769104,
-0.08083826303482056,
-0.04702406004071236,
-0.017430871725082397,
-0.02938094176352024,
0.0021653990261256695,
0.03495842218399048,
0.05129211023449898,
0.04687606170773506,
-0.031645964831113815,
0.0183... |
10,000,374 | The effect of estrogen treatment on risk for cholecystectomy, cholelithiasis, peptic ulcer, and other disorders was investigated using autopsy data from a study of patients randomized to hormonal therapy for prostatic cancer. Treatment with diethylstilbestrol, a nonsteroidal estrogen, was associated with an increased n... | [
0.04641664773225784,
-0.10001227259635925,
-0.016934040933847427,
0.014577465131878853,
-0.009825167246162891,
-0.05023116618394852,
-0.002734363777562976,
0.06483054161071777,
-0.0032504750415682793,
-0.017791466787457466,
0.03569798171520233,
0.027149422094225883,
-0.02626265585422516,
-... |
10,000,375 | Gastric emptying as a determinant of the oral glucose tolerance test. | [
0.08649174124002457,
0.03252289071679115,
-0.12161649763584137,
0.038630660623311996,
-0.025275828316807747,
-0.023022009059786797,
0.07165766507387161,
0.05617533624172211,
-0.003905326360836625,
-0.06724725663661957,
-0.030631503090262413,
-0.013915215618908405,
-0.07577291876077652,
0.0... |
10,000,376 | Intraindividual variation in the results of repeated oral glucose tolerance tests in normal subjects is well recognized but incompletely explained. The present studies show that such variation can be produced by ingestion of the glucose solution during different phases of the normal fasting activity cycle of the upper ... | [
0.06358522921800613,
-0.05269632115960121,
-0.0753118097782135,
0.0139317587018013,
-0.03480919077992439,
-0.010819638147950172,
0.02397683635354042,
0.07993154227733612,
-0.011600665748119354,
-0.0513661652803421,
-0.0292563084512949,
0.027003062888979912,
-0.003804978681728244,
0.0293953... |
10,000,377 | Identification of NH2-terminal fragments of big gastrin in plasma. | [
-0.024083951488137245,
0.014259172603487968,
-0.013789424672722816,
-0.01659904420375824,
0.06993629783391953,
0.011630885303020477,
0.013065789826214314,
0.04523802548646927,
0.040936000645160675,
-0.047073736786842346,
-0.00327148474752903,
-0.0472402460873127,
-0.12248222529888153,
0.07... |
10,000,378 | Molecular forms of gastrin in human plasma were studied by radioimmunoassay using antisera specific for the NH2-terminus of big gastrin (gastrin 34). A plasma enzyme system that destroys immunoreactivity of NH2-terminal fragments of gastrin 34, but not of gastrin 34 itself, has been demonstrated and shown to be inhibit... | [
0.0029421772342175245,
-0.05336084961891174,
-0.08972077071666718,
-0.019215019419789314,
0.0420648492872715,
0.039344314485788345,
0.07996489852666855,
0.10218050330877304,
0.028987055644392967,
-0.008123161271214485,
0.0047895717434585094,
-0.025470197200775146,
-0.10257575660943985,
0.0... |
10,000,379 | Converting a stomach to a uterus: the microscopic structure of the stomach of the gastric brooding frog Rheobatrachus silus. | [
0.032284926623106,
0.0022307978942990303,
-0.07695065438747406,
0.023373136296868324,
-0.045663923025131226,
0.014579016715288162,
0.02293304353952408,
0.020852411165833473,
-0.011995712295174599,
-0.010112048126757145,
-0.03467107191681862,
-0.08465050160884857,
-0.01900273561477661,
0.01... |
10,000,380 | Rheobatrachus silus is a rare aquatic frog of eastern Australia. The female ingests the eggs after fertilization and broods them in the stomach until fully formed. "Gastric brooding" takes place in the fundus and proximal part of the body of the stomach, which dilates to accommodate the growing young. The surface epith... | [
0.026139741763472557,
-0.029009241610765457,
-0.0708995908498764,
0.013269015587866306,
0.06702981889247894,
0.09092632681131363,
0.06171388551592827,
0.06153556704521179,
0.02172733284533024,
0.02981947548687458,
-0.01872428134083748,
-0.053442731499671936,
0.008100208826363087,
0.0287685... |
10,000,381 | Free-market system is still the best answer. | [
-0.007090479601174593,
-0.03516455367207527,
-0.03581313043832779,
-0.03047783300280571,
0.08551566302776337,
0.07336348295211792,
-0.037217024713754654,
0.053364500403404236,
0.022172866389155388,
0.004271988291293383,
0.06313791871070862,
0.05304816737771034,
-0.00819147564470768,
0.0075... |
10,000,382 | Serum primary bile acids in Gilbert's syndrome. | [
-0.014549651183187962,
-0.02703733928501606,
-0.07903914153575897,
0.035749636590480804,
-0.10405373573303223,
0.07285311073064804,
0.04907376319169998,
0.0925910472869873,
-0.002664858940988779,
-0.03824325278401375,
0.04105403646826744,
-0.011108704842627048,
-0.036185190081596375,
0.004... |
10,000,383 | We studied some aspects of bile acid metabolism in 25 patients affected by Gilbert's syndrome, 5 patients with hemolytic anemia, and 25 control subjects in order to assess whether bile acids as well as bilirubin are affected in unconjugated hyperbilirubinemic conditions. We measured serum cholic and chenodeoxycholic ac... | [
0.029294665902853012,
-0.08001339435577393,
-0.08141118288040161,
0.07356011122465134,
-0.08656726777553558,
0.03375380113720894,
-0.009670862928032875,
0.06747584044933319,
0.011663028039038181,
-0.06885559856891632,
0.0021346556022763252,
0.03308466821908951,
0.015214771963655949,
0.0062... |
10,000,384 | Survey provides data on in-house planners and formalized planning. | [
0.03132866695523262,
0.01953916810452938,
0.013665199279785156,
0.0651460662484169,
0.024366455152630806,
-0.011076383292675018,
-0.03485674783587456,
0.0015282643726095557,
-0.1325225830078125,
0.06582771986722946,
-0.07124564796686172,
-0.03370077535510063,
-0.016203029081225395,
0.03444... |
10,000,385 | Product-oriented management helps hospital fight administrative problems. | [
0.0077954805456101894,
0.0040374817326664925,
0.04522592946887016,
-0.03798186779022217,
-0.03903656825423241,
0.03026694804430008,
0.06647270172834396,
0.052398983389139175,
-0.031170591711997986,
0.013805896043777466,
-0.011373069137334824,
0.07754839956760406,
0.04339244216680527,
0.040... |
10,000,386 | Adoptive parent program aids parents to be. | [
-0.07519599050283432,
0.05310184136033058,
0.04671376571059227,
0.002302519278600812,
-0.001663118600845337,
0.022999104112386703,
-0.04526674374938011,
0.012031891383230686,
-0.024615993723273277,
-0.01711159758269787,
0.07778502255678177,
0.005418690852820873,
-0.00795716978609562,
-0.04... |
10,000,387 | Nurse-extern program eases "reality shock" for new staff nurses. | [
-0.06071440875530243,
-0.08681774139404297,
-0.0024428539909422398,
0.028083786368370056,
0.06960681825876236,
-0.021986324340105057,
-0.031915102154016495,
0.013165278360247612,
0.03174784034490585,
-0.06795810163021088,
-0.004716816358268261,
0.027091408148407936,
-0.030915293842554092,
... |
10,000,388 | Shared pharmacy arrangement benefits hospital and nearby convalescent center. | [
-0.051807258278131485,
0.04666052386164665,
-0.02628985047340393,
-0.030829815194010735,
-0.07794160395860672,
0.06037595868110657,
-0.013214681297540665,
0.024171410128474236,
0.04774346575140953,
-0.0655144453048706,
-0.021850602701306343,
0.07093892991542816,
0.048071227967739105,
0.026... |
10,000,389 | Hospital trusteeship: liability and protection. | [
0.013460630550980568,
0.08475324511528015,
-0.014126375317573547,
-0.03858255222439766,
-0.018963845446705818,
0.011652600020170212,
-0.018937930464744568,
-0.0010235811350867152,
0.06862275302410126,
0.009795404970645905,
0.020047344267368317,
-0.016621695831418037,
0.04589569941163063,
-... |
10,000,390 | No more business as usual. | [
0.0275706984102726,
0.0036858164239674807,
0.055047377943992615,
-0.03291235864162445,
-0.040831878781318665,
-0.04996021091938019,
-0.0990225076675415,
-0.03696659952402115,
0.011009317822754383,
-0.04318663105368614,
0.04108276218175888,
0.12047787010669708,
-0.056409500539302826,
0.0136... |
10,000,391 | It's going to hurt for more than just a little while. | [
0.025087833404541016,
-0.048412226140499115,
0.05574764311313629,
0.022481458261609077,
-0.016629640012979507,
0.01311534270644188,
-0.07277097553014755,
0.027506692335009575,
-0.02669411152601242,
-0.020341472700238228,
-0.05157960578799248,
0.06637286394834518,
-0.02064872346818447,
0.10... |
10,000,392 | Medical care prices rising faster than overall CPI. | [
-0.013314959593117237,
-0.026946190744638443,
0.0032431704457849264,
0.006469326559454203,
0.049814723432064056,
-0.03057491034269333,
-0.10337468236684799,
0.042236194014549255,
0.06860309839248657,
-0.0028720926493406296,
0.03170565143227577,
0.05393090471625328,
-0.05048638954758644,
-0... |
10,000,393 | September expense rate is lowest in nine months. | [
0.0911090224981308,
0.0181377325206995,
-0.0024353424087166786,
0.011371497064828873,
0.03256918862462044,
0.0399678498506546,
-0.11804880946874619,
0.06343117356300354,
-0.0476088672876358,
0.0047354320995509624,
0.018721945583820343,
-0.059445321559906006,
-0.023057052865624428,
0.032082... |
10,000,394 | New 'employment line' is less costly, but effective tool for advertising hospital's job opportunities. | [
-0.048044003546237946,
0.056776851415634155,
0.0026382675860077143,
0.025477126240730286,
0.03673224151134491,
0.013030890375375748,
-0.06871472299098969,
0.06578082591295242,
0.017023544758558273,
-0.07600279897451401,
-0.04855921119451523,
0.07033419609069824,
-0.003703533438965678,
0.01... |
10,000,395 | Sharing work experiences helps ED nurses, paramedics improve communications. | [
-0.08065906912088394,
-0.000494179199449718,
0.0036844671703875065,
-0.008267734199762344,
-0.012677947990596294,
0.014692774973809719,
-0.008678308688104153,
-0.017144223675131798,
0.05126610025763512,
-0.10190946608781815,
-0.0819166973233223,
0.12312780320644379,
-0.03559291735291481,
0... |
10,000,396 | Gamble on food service technology pays off at United Hospitals. | [
-0.005235054064542055,
0.01761966198682785,
0.033166781067848206,
-0.036523208022117615,
-0.0804448127746582,
0.015371453016996384,
0.07140541821718216,
-0.08163690567016602,
0.017605243250727654,
-0.07304277271032333,
0.0010175207862630486,
0.07451259344816208,
-0.03170819953083992,
-0.03... |
10,000,397 | High school for health professions uses hospital for classrooms. | [
0.006314080208539963,
0.10974196344614029,
-0.02279673144221306,
-0.050598639994859695,
-0.043344296514987946,
-0.001846597297117114,
-0.020070476457476616,
0.04684257507324219,
0.05205632373690605,
0.04326968640089035,
0.02080698311328888,
0.13397787511348724,
-0.03683526813983917,
0.0350... |
10,000,398 | Engineering department uses 'quick slip' to handle minor repairs in hospital. | [
-0.07292420417070389,
0.00935649499297142,
0.11041570454835892,
0.004577009007334709,
0.008285359479486942,
-0.024344613775610924,
0.00026926115970127285,
0.05437220260500908,
0.023073092103004456,
-0.014183273538947105,
0.09490711241960526,
0.06490499526262283,
-0.020419662818312645,
0.01... |
10,000,399 | Vinyl graphics bring appeal, color to patient care areas. | [
0.03040466085076332,
0.08665897697210312,
0.039132971316576004,
-0.08715883642435074,
-0.04224727675318718,
0.0391252301633358,
0.037530556321144104,
0.021621599793434143,
0.005061599891632795,
-0.046410247683525085,
-0.051345955580472946,
0.060743607580661774,
-0.01747506484389305,
0.0337... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.