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10,004,300
Chemical carcinogens from several diverse chemical classes i.e.; aromatic amines, polycyclic hydrocarbons, nitrosamines, hormonal derivatives, metals and direct alkylating agents cause a 6.2-60.5-fold increase in the frequency of murine sarcoma virus (MSV)-induced transformation in a normal rat kidney (NRK) cell system...
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10,004,301
The functional role of structural complexities in the propagation of depolarization in the atrium of the dog. Cardiac conduction disturbances due to discontinuities of effective axial resistivity.
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10,004,302
Effects of the discrete pattern of electrical coupling on propagation through an electrical syncytium.
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10,004,303
We used numerical integration techniques to simulate action potential propagation along one-dimensional strands of cells coupled with electrical junctions. We considered the standard case to be a series of cardiac cells (20 micrometer in diameter, 50 micrometers long) with intercellular coupling such that the effective...
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10,004,304
PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium.
[ -0.019949952140450478, -0.03800644353032112, 0.031827013939619064, -0.10725439339876175, 0.06464725732803345, -0.08102679252624512, -0.024919217452406883, 0.07536789774894714, 0.05319856107234955, 0.04979737102985382, 0.026517489925026894, -0.03304796665906906, 0.03490017354488373, 0.11137...
10,004,305
Altered left ventricular diastolic properties during pacing-induced ischemia in dogs with coronary stenoses. Potentiation by caffeine.
[ -0.010793128050863743, -0.0044508217833936214, -0.03990565240383148, 0.14116306602954865, 0.028539394959807396, 0.028032774105668068, -0.029771756380796432, -0.04663657769560814, 0.05836125835776329, -0.058775708079338074, -0.04815327376127243, -0.008750028908252716, 0.031236281618475914, ...
10,004,306
Electrophysiological and electron microscopic correlations concerning the effects of neuraminidase on canine heart cells.
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10,004,307
Microcirculation of left atrial muscle, cerebral cortex and mesentery of the cat. A comparative analysis.
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10,004,308
By means of transillumination (microtransilluminator and light pipe), comparative analyses were carried out on geometry, topography, and morphometry of microcirculation in the cerebral cortex, left atrial muscle, and mesentery of the cat using computer analysis. In addition, specific types of capillary distribution (co...
[ 0.027561720460653305, -0.006744700483977795, 0.0027165596839040518, 0.03467821702361107, 0.005607494153082371, -0.05378622189164162, 0.050119321793317795, 0.09417609870433807, 0.02884851209819317, 0.012508785352110863, 0.04457760229706764, -0.07923687249422073, 0.010191435925662518, 0.1045...
10,004,309
Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles.
[ 0.03109518624842167, -0.03224143758416176, 0.03267941251397133, 0.04669424518942833, -0.021540092304348946, -0.03463873267173767, -0.010807323269546032, 0.012421107850968838, 0.10925902426242828, 0.05249631777405739, 0.010213569737970829, -0.011346803978085518, 0.047753237187862396, 0.1091...
10,004,310
Using highly purified sarcolemmal vesicles isolated from dog ventricles, we examined the effects of pH on Na+-Ca2+ exchange. The initial rate of Nai+-dependent Ca2+ uptake is a sigmoid function of pH. The Ca2+ uptake is inhibited at pH 6 and stimulated at pH 9 (as compared with uptake at pH 7.4). This dependence on pH ...
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10,004,311
Role of renal nerves, angiotensin II, and prostaglandins in the antinatriuretic response to acute hypercapnic acidosis in the dog.
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10,004,312
Although clinical studies suggest that chronic hypercapnic acidosis may be associated with renal sodium retention, little information is available on the effect of acute hypercapnic acidosis on renal sodium excretion. We, therefore, increased PCO2 from 23 to 74 mm Hg in anesthetized dogs and observed a marked antinatri...
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10,004,313
Non-hydrostatic pulmonary edema after coronary artery ligation in dogs. Protective effect of indomethacin.
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10,004,314
Pulmonary edema which develops during acute myocardial infarction is generally believed to result solely from pulmonary microvascular hypertension. However, patient with myocardial infarction and pulmonary edema occasionally are found to have normal pulmonary wedge pressure. We report data indicating that pulmonary ede...
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10,004,315
Intracardiac extrastimulation studies: How to? Where? By whom?
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10,004,316
Prolongation of atrioventricular conduction time by electrical stimulation of the carotid sinus nerves in man.
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10,004,317
Electrical stimulation of the carotid sinus nerves was applied during diagnostic catheterization of two patients who had coronary artery disease. The immediate reflex prolongation of the atrioventricular (AV) interval was due to prolongation of the AH interval only and was roughly parallel to the reflex RR interval pro...
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10,004,318
Influence of heart rate and inhibition of autonomic tone on the QT interval.
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10,004,319
To evaluate whether heart-rate-induced changes of the QT interval are dependent on autonomic tone, we studied 13 healthy subjects, mean age 67.5 years. The maximal uncorrected QT from leads I, II, V1 and V6 was determined during atrial pacing at 90 beats/min and 130 beats/min before and after i.v. administration of pro...
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10,004,320
The effect of high lung conductivity on electrocardiographic potentials. Results from human subjects undergoing bronchopulmonary lavage.
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10,004,321
The effect of increased lung conductivity on ECG potentials was studied in human subjects undergoing pulmonary lavage of a whole lung. In this procedure, the air in the lung is replaced by physiologic saline solution, which is a highly conductive fluid. The same situation was simulated theoretically with an eccentric s...
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10,004,322
Survival of patients with a strongly positive exercise electrocardiogram.
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10,004,323
To assess the prognosis of patients with a strongly positive exercise ECG, the 5-year cumulative survival rate was computed for 220 medically treated patients. Of these patients, 107 had coronary angiograms (group A) and 113 did not (group B). All had horizontal or downsloping ST depression greater than or equal to 2 m...
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10,004,324
Clinical classification of cardiac deaths.
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10,004,325
One hundred forty-two deaths among 743 men ages 50 - 65 years who had been examined and followed 5 - 10 years were investigated and classified on the basis of clinical information from medical and non-medical observers, ECGs and autopsies. A classification based on the condition of the circulation immediately before de...
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10,004,326
The effects of cigarette smoke and nicotine on platelet thrombus formation in stenosed dog coronary arteries: inhibition with phentolamine.
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10,004,327
This study was undertaken to examine in vivo the effects of cigarette smoke on cyclic reductions in coronary flow due to platelet thrombus formation in the stenosed coronary arteries of anesthetized dogs. The circumflex coronary artery of 21 mongrel dogs was stenosed 60 - 80%, with blood flow measured with an electroma...
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10,004,328
Changes in plasma lipid and lipoprotein levels in men and women after a program of moderate exercise.
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10,004,329
Levels of high-density lipoprotein (HDL) cholesterol and other lipids and lipoproteins of 24 men and 37 women were measured before and after a 10-week exercise program. The program involved three sessions of aerobic exercise each week, with 15-20 minutes of activity at 70% of maximal heart rate. Men and women had signi...
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10,004,330
Left ventricular function in trained and untrained healthy subjects.
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10,004,331
Left ventricular function was compared in 18 normal sedentary controls (mean age 28 years, range 22 - 34 years) and nine endurance-trained athletes (mean age 19 years, range 15 - 25 years) at rest and during supine bicycle exercise. Gated radionuclide angiocardiograms were performed at rest and at each level of graded ...
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10,004,332
Acute hemodynamic responses to sublingual nifedipine: dependence on left ventricular function.
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10,004,333
Studies of amiodarone during experimental myocardial infarction: beneficial effects on hemodynamics and infarct size.
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10,004,334
The effect of amiodarone was investigated in a canine model of myocardial infarction. The left anterior descending coronary artery was occluded in 24 anesthetized dogs. After 15 minutes of coronary artery occlusion, the ischemic myocardium at risk of necrosis was determined by labeling the heart with technetium-99m-lab...
[ 0.03876456990838051, 0.020528385415673256, 0.028528345748782158, 0.034018535166978836, 0.06598877161741257, -0.05994557589292526, -0.06014006957411766, 0.1385071575641632, 0.041434600949287415, -0.03856344893574715, 0.028330575674772263, -0.011454441584646702, 0.025492584332823753, 0.10382...
10,004,335
The role of right ventricular systolic dysfunction and elevated intrapericardial pressure in the genesis of low output in experimental right ventricular infarction.
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10,004,336
To elucidate the pathophysiology of severe right ventricular infarction (RVI), isolated RVI was produced in 15 dogs with the pericardium intact or open. After RVI in dogs with the pericardium intact, RV systolic pressure decreased by 27%, aortic pressure by 29% and cardiac output by 34%. RV transmural pressure, RV end-...
[ -0.016143949702382088, 0.040283266454935074, 0.004612701013684273, 0.021229030564427376, 0.02198772132396698, -0.009718869812786579, -0.11599689722061157, -0.045611798763275146, 0.05614665523171425, -0.041361719369888306, 0.027220066636800766, -0.010327445343136787, 0.00580468587577343, 0....
10,004,337
Effects of hydralazine on coronary blood flow and myocardial energetics in congestive heart failure.
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10,004,338
The acute effects of oral hydralazine, 1 mg/kg, on coronary vascular resistance, coronary blood flow (estimated using the coronary sinus thermodilution technique), and myocardial oxygen consumption were evaluated in 10 patients with chronic (New York Heart Association class III and IV) nonischemic congestive heart fail...
[ 0.0395648255944252, 0.0030451565980911255, -0.04539410397410393, 0.021899748593568802, -0.00945931114256382, -0.0527498722076416, -0.06345093995332718, 0.10863377898931503, 0.015780573710799217, -0.034816522151231766, -0.12462259829044342, -0.02773923985660076, -0.012423526495695114, 0.062...
10,004,339
Effect of coronary blood flow on thallium-201 uptake and washout.
[ 0.05026612430810928, -0.012928920798003674, -0.025034502148628235, 0.03836323693394661, 0.0018078022403642535, -0.07939599454402924, -0.01774907484650612, 0.08026812225580215, 0.04737670347094536, -0.0868280753493309, -0.04108600318431854, 0.021389750763773918, 0.014522195793688297, 0.0303...
10,004,340
Myocardial uptake and washout of thallium-201 (201TI) were studied in an experimental dog model in which regional blood flow to the posterior wall was varied by transient 2-minute occlusion of the circumflex coronary artery to produce transient ischemia and reactive hyperemia. Thallium-201 myocardial activity in a regi...
[ 0.07319922745227814, -0.03666791692376137, 0.022337375208735466, 0.06246602535247803, -0.005469821393489838, -0.046520013362169266, -0.050470151007175446, 0.07167918980121613, 0.08564785867929459, -0.05830371752381325, -0.021886883303523064, 0.03750211000442505, 0.0670340433716774, 0.05341...
10,004,341
Gamma camera quantitation of thallium-210 redistribution at rest in a dog model.
[ -0.041617121547460556, -0.11291211098432541, 0.03196640685200691, 0.013668704777956009, 0.0029617794789373875, -0.0533466637134552, 0.030192546546459198, 0.08062049001455307, 0.06960933655500412, -0.0181269533932209, 0.12556879222393036, -0.00887729600071907, 0.06212481111288071, 0.0853697...
10,004,342
Defects seen at rest on thallium-201 (201TI) scintigraphy can disappear over time. We obtained sequential 5-minute scans over 127 +/- 9.4 minutes in seven open-chest dogs with fixed, stable regional flow reductions (normal zone flow 0.76 +/- 0.09 ml g-1/min, ischemic zone flow 0.49 +/- 0.04 ml g-1 min [mean +/- SEM], p...
[ 0.05682254955172539, -0.050297293812036514, 0.07593996822834015, -0.023122787475585938, -0.008696012198925018, -0.08938375860452652, -0.025507424026727676, 0.08079656213521957, 0.037595219910144806, 0.018050042912364006, 0.02255040779709816, 0.002874914789572358, 0.05654237046837807, 0.082...
10,004,343
The phase image: its relationship to patterns of contraction and conduction.
[ -0.046138543635606766, -0.03788064792752266, 0.06690995395183563, 0.05637660622596741, -0.05727284029126167, 0.043172791600227356, 0.01891278102993965, -0.019034527242183685, 0.09593820571899414, 0.0101728904992342, 0.03162344917654991, -0.03847537934780121, 0.03956915810704231, 0.05404433...
10,004,344
To determine the relationship of phase changes and abnormalities of ventricular contraction and conduction, we performed phase image analysis of blood pool scintigrams in 29 patients. Eleven patients had no evidence of blood pool contraction or ECG conduction abnormalities, four had contraction abnormalities, seven had...
[ 0.023376548662781715, -0.019279442727565765, 0.047428157180547714, -0.0008591396035626531, -0.007275623735040426, -0.014762366190552711, -0.032012660056352615, -0.045123253017663956, 0.08430604636669159, -0.10670427978038788, 0.016924863681197166, -0.02510274201631546, 0.003379595698788762, ...
10,004,345
Comparative value of the cold-pressor test and supine bicycle exercise to detect subjects with coronary artery disease using radionuclide ventriculography.
[ 0.040589675307273865, 0.03286250680685043, -0.08975959569215775, 0.05108051374554634, 0.01192920096218586, 0.009122992865741253, -0.062337715178728104, 0.019669223576784134, 0.06652068346738815, -0.03743673861026764, 0.010195841081440449, -0.016485176980495453, 0.11793515086174011, 0.06348...
10,004,346
Quantitative analysis of segmental wall motion throughout systole and diastole in the normal human left ventricle.
[ 0.08567465841770172, -0.027226904407143593, 0.01418128702789545, -0.054628897458314896, 0.004147348925471306, -0.012791086919605732, -0.08691853284835815, -0.07933692634105682, 0.0492638535797596, -0.08824654668569565, -0.001105634612031281, 0.0028248983435332775, 0.0025755069218575954, 0....
10,004,347
We traced left ventricular contours, frame-by-frame throughout systole and diastole, of normal sinus beats from 30 degrees right anterior oblique ventriculograms from 32 normal patients. We separated both systole and diastole into 19 equal time intervals each and calculated regional lengths (R), normalized by both end-...
[ 0.07612238079309464, 0.01845918968319893, 0.004426049068570137, -0.05385877564549446, -0.012065569870173931, 0.006183471996337175, -0.13915026187896729, -0.001440997701138258, 0.04647475481033325, -0.10337287932634354, 0.032115206122398376, -0.009206892922520638, 0.013753552921116352, 0.03...
10,004,348
Noninvasive visualization of the dilated main coronary arteries in coronary artery fistulas by cross-sectional echocardiography.
[ 0.12649357318878174, -0.047282829880714417, 0.014997153542935848, -0.01718171127140522, -0.012044168077409267, -0.07052360475063324, -0.09153392910957336, -0.0058706384152174, 0.09820336103439331, -0.10538426041603088, -0.012787975370883942, -0.024651722982525826, -0.03730366751551628, 0.0...
10,004,349
Real-time cross-sectional echocardiographic studies of the main coronary arteries were performed in 20 normal subjects, 12 patients with patent ductus arteriosus and 14 patients with coronary artery fistula in whom the diagnosis was established by angiography. In 12 patients, the coronary artery that formed the fistula...
[ 0.04522392898797989, 0.009598244912922382, 0.06672156602144241, 0.010453281924128532, -0.023543458431959152, -0.04912737011909485, -0.09632662683725357, 0.02822425588965416, 0.06517163664102554, -0.07841547578573227, 0.0003408543998375535, -0.006949662696570158, -0.07958397269248962, 0.002...
10,004,350
Effect of cough on coronary perfusion pressure: Does coughing help clear the coronary arteries of angiographic contrast medium?
[ 0.05978397652506828, 0.032070498913526535, -0.008152461610734463, 0.024676181375980377, 0.028712449595332146, -0.009378687478601933, 0.025719791650772095, 0.028013555333018303, 0.06342687457799911, -0.03390826657414436, -0.04473717883229256, 0.01719500496983528, 0.05402577295899391, 0.0469...
10,004,351
Pulsus alternans determined by biventricular simultaneous systolic time intervals.
[ -0.03978089615702629, -0.048950664699077606, -0.031136073172092438, -0.014158202335238457, -0.11591620743274689, 0.012753223069012165, -0.08141857385635376, -0.01952892728149891, 0.049041539430618286, -0.05636405199766159, 0.0781770721077919, -0.04591906815767288, -0.023120436817407608, -0...
10,004,352
This investigation was performed to determine the presence of unilateral or bilateral pulsus alternans in the systemic and pulmonary circulations in heart failure and to estimate the prevalence of pulsus alternans in congestive cardiomyopathy. The subjects were 36 adult patients in heart failure due to a variety of car...
[ -0.02270316332578659, -0.042321667075157166, 0.006740448530763388, 0.06002512946724892, -0.00777603080496192, 0.020699892193078995, -0.09146148711442947, -0.02277393266558647, 0.008871729485690594, -0.06708501279354095, 0.03514677286148071, -0.04269924387335777, 0.007293432950973511, 0.037...
10,004,353
Termination of ventricular tachycardia by carotid sinus massage.
[ -0.006922026164829731, 0.066834457218647, -0.027931544929742813, 0.045535679906606674, -0.03986070677638054, -0.00360902794636786, -0.03383534401655197, -0.08713188022375107, 0.03544212132692337, -0.09769453853368759, 0.04771377518773079, -0.004310403950512409, -0.024718472734093666, 0.051...
10,004,354
Intracardiac electrophysiologic studies were performed in two patients who had recurrent sustained ventricular tachycardia. In both, the tachycardia was repeatedly terminated by carotid massage. In one patient, intracardiac electrophysiologic studies revealed ventricular tachycardia with 2:1 retrograde ventriculoatrial...
[ -0.05253259465098381, 0.01732153631746769, 0.02243003249168396, 0.034924060106277466, -0.025888677686452866, -0.03098716028034687, -0.06773707270622253, -0.06676032394170761, 0.03461223840713501, -0.10755862295627594, 0.07161402702331543, 0.017443541437387466, -0.020331891253590584, 0.0109...
10,004,355
Ejection performance in AS.
[ 0.04713771119713783, 0.05441427230834961, 0.028512440621852875, 0.06824380904436111, -0.0583156943321228, -0.023786088451743126, 0.07374124228954315, 0.00029236669070087373, -0.012563880532979965, 0.00044853767030872405, 0.019219674170017242, 0.029126206412911415, -0.015106366015970707, 0....
10,004,356
Irreversible coronary occlusion and ergonovine.
[ 0.0329904779791832, 0.046166833490133286, -0.03631328418850899, 0.11751466989517212, 0.08113642781972885, -0.007524957414716482, 0.01173379085958004, 0.11847762018442154, 0.08396042138338089, -0.05733918026089668, -0.05350979045033455, 0.05032182112336159, 0.009393196552991867, 0.053598701...
10,004,357
First-pass technique and diastolic phenomena.
[ -0.010343247093260288, -0.012398897670209408, -0.05477935075759888, -0.028354475274682045, -0.14410056173801422, -0.012524735182523727, -0.035336028784513474, -0.0067272852174937725, 0.043065935373306274, -0.0786203071475029, 0.0328826904296875, 0.06113509088754654, -0.0039590755477547646, ...
10,004,358
Probability of CAD.
[ 0.03754542022943497, 0.0911138653755188, -0.020898204296827316, -0.010726841166615486, -0.07185167819261551, -0.10254192352294922, 0.02796354331076145, 0.11143318563699722, 0.008497674018144608, 0.01375284232199192, 0.02081434428691864, -0.07988231629133224, 0.02962985821068287, 0.02953926...
10,004,359
Can myocardial ischemia be imaged with technetium-99m-Sn-2+-pyrophosphate?
[ -0.011071343906223774, 0.003648321609944105, -0.004834392108023167, -0.04716978967189789, 0.0959465429186821, -0.05318598076701164, 0.057425856590270996, 0.12122601270675659, -0.04614681750535965, 0.0020089761819690466, -0.0024966427590698004, 0.012655233964323997, 0.024326911196112633, 0....
10,004,360
Manual for evaluation of lung function by spirometry. Prepared by the Cardiopulmonary Council of the American Heart Association.
[ 0.048323892056941986, -0.00916365161538124, -0.04859326407313347, -0.0068703340366482735, -0.010897590778768063, 0.013986202888190746, -0.08134647458791733, 0.043271373957395554, -0.02791440486907959, 0.013584287837147713, 0.020349353551864624, 0.046171292662620544, -0.018384959548711777, ...
10,004,361
Laboratory evaluation of the Boehringer Mannheim "Diagnostic M" automated discrete analyzer.
[ -0.03582913056015968, 0.0500243715941906, -0.06538619846105576, -0.051389481872320175, -0.07057221978902817, -0.09182493388652802, 0.003497509751468897, 0.05744568258523941, 0.00595433684065938, -0.006993997376412153, 0.009960949420928955, -0.06941000372171402, 0.01725168153643608, 0.04859...
10,004,362
We evaluated a new multiple-channel chemistry analyzer, the Boehringer Mannheim "Diagnostic M." This instrument can perform 25 tests at the rate of 120 1.3-mL serum samples per hour. The instrument may be run in either a profile mode or single-test mode. In the single-test mode only the necessary reagent is pumped. the...
[ 0.00823959894478321, -0.06744147092103958, -0.09185035526752472, -0.047410160303115845, -0.02901541255414486, -0.043928299099206924, -0.03577746823430061, 0.09938429296016693, 0.011291418224573135, -0.02273383177816868, -0.024494120851159096, -0.06722335517406464, -0.01195781584829092, 0.0...
10,004,363
Assays of serum lipase by the "BALB-DTNB method" mechanized for use with discrete and continuous-flow analyzers.
[ -0.0889689028263092, -0.12085723131895065, -0.07836436480283737, -0.05294017493724823, -0.04629521444439888, 0.01431815605610609, -0.038736581802368164, 0.08254866302013397, -0.05521729588508606, -0.05924712494015694, -0.05297207087278366, -0.057840846478939056, -0.05535407364368439, 0.048...
10,004,364
We successfully adapted the dimercaprol (BAL) tributyrate-5,5'-dithiobis(2-nitrobenzoic acid) method (J. Biochem. 81: 361, 1977) for assay of lipase in human serum to a discrete analyzer (the TBA 880) (I) or a continuous-flow analyzer (AutoAnalyzer, Type II) (II). In both, BAL-tributyrate is used as substrate, in combi...
[ -0.018492963165044785, -0.07350070774555206, -0.09463359415531158, -0.07568368315696716, -0.007457948289811611, 0.06742801517248154, -0.044385410845279694, 0.1356954723596573, 0.007386180572211742, -0.0392017625272274, -0.031675465404987335, -0.06112804263830185, -0.053022246807813644, 0.0...
10,004,365
An enzymic, reaction-rate assay for serum creatinine with a centrifugal analyzer.
[ -0.024651220068335533, -0.07184802740812302, -0.04044908285140991, -0.004488460253924131, 0.05992148071527481, -0.008603068068623543, -0.034923192113637924, 0.12164881825447083, -0.012922335416078568, -0.022365128621459007, -0.03388287499547005, -0.12386415898799896, -0.019405679777264595, ...
10,004,366
We describe a procedure for specific, rapid, kinetic determination of creatinine, in which a manual coupled-enzyme micro-scale assay is adapted to a centrifugal analyzer. The creatinine reaction is ultimately linked to NADH utilization, which is measured by the absorbance change at 340 nm. This procedure requires 15 mi...
[ -0.0025690700858831406, -0.07906607538461685, -0.03308158740401268, -0.030975759029388428, 0.055569522082805634, -0.004872689954936504, -0.05914069712162018, 0.11868943274021149, -0.009096176363527775, -0.030375128611922264, -0.03733265399932861, -0.07936456799507141, -0.014024035073816776, ...
10,004,367
Detergent activation of the binding protein in the folate radioassay.
[ 0.036181434988975525, -0.057419758290052414, -0.09599465131759644, 0.006820851471275091, 0.05432843416929245, -0.00920349732041359, 0.04095737636089325, 0.047401368618011475, 0.00748783815652132, -0.017107175663113594, 0.07544144988059998, -0.038254041224718094, 0.01366919744759798, 0.0635...
10,004,368
A minor cow's whey protein associated with beta-lactoglobulin is used as binding protein in the competitive radioassay for serum and erythrocyte folate. Seeking to optimize the assay, we tested the performance of binder solutions of increasing purity. The folate binding protein was isolated from cow's whey by means of ...
[ -0.0117551414296031, -0.16513940691947937, -0.07158329337835312, -0.011965371668338776, 0.03595488518476486, 0.04456981271505356, 0.041637618094682693, 0.11756408959627151, 0.0026685905177146196, -0.054986972361803055, 0.016641154885292053, -0.028258664533495903, 0.015705185011029243, 0.04...
10,004,369
Evaluation of a commercially available radioimmunoassay kit for measurement of doxorubicin in plasma.
[ 0.007542815525084734, 0.02128327079117298, -0.06342969834804535, -0.009292066097259521, -0.03495877608656883, -0.0850805714726448, 0.04571991041302681, 0.1602504849433899, 0.0689825713634491, -0.0841975137591362, -0.01549594011157751, -0.057580407708883286, 0.031490594148635864, 0.11813766...
10,004,370
We evaluated a commercially available (Diagnostic Biochemistry Inc.) doxorubicin 125I radioimmunoassay kit. This kit gave a high apparent doxorubicin concentration (greater than 12 micrograms/L), which was not linearly related to dilution, for two pools of normal human serum and plasma and also for samples collected fr...
[ 0.08051785081624985, 0.018693333491683006, -0.04852735623717308, -0.026846321299672127, -0.0347740612924099, -0.10548845678567886, 0.022054191678762436, 0.2137867957353592, 0.07615334540605545, -0.04999632015824318, -0.005539954639971256, -0.032960444688797, 0.0629139319062233, 0.103682599...
10,004,371
Reference intervals for serum IgG, IgA, IgM, C3, and C4 as determined by rate nephelometry.
[ -0.017674613744020462, 0.019777793437242508, -0.022835584357380867, 0.0049762665294110775, -0.05789465457201004, 0.003945854026824236, 0.0093325050547719, 0.14055322110652924, -0.005076956003904343, 0.011957435868680477, -0.042190395295619965, -0.09762639552354813, -0.027413731440901756, 0...
10,004,372
We report reference intervals for IgG, IgA, IgM, C3, and C4 for a population of 750 well children and 120 healthy adults. Ranges were established by rate nephelometry (previous studies have been based on immunodiffusion). Our results generally agree with previously established immunoglobulin ranges, except for some dis...
[ 0.0021245128009468317, 0.0439782477915287, 0.0496610589325428, 0.03334078565239906, -0.11264745146036148, -0.0034111535642296076, 0.03674981743097305, 0.14614102244377136, -0.03878895938396454, 0.012999055907130241, -0.05198196321725845, -0.029485249891877174, 0.0023165594320744276, 0.0494...
10,004,373
Comparative evaluation of two calcium ion-selective electrode systems, and their utility for monitoring steady-state changes in [Ca2+].
[ -0.02014271914958954, -0.0016600616509094834, 0.08101872354745865, 0.059094030410051346, 0.010550465434789658, -0.023177124559879303, 0.021041501313447952, 0.020131181925535202, 0.11603336036205292, 0.11177220940589905, -0.01447361521422863, -0.08816293627023697, 0.053806599229574203, 0.08...
10,004,374
We compared ionized calcium concentrations ([Ca2+]) as measured with two ionized-calcium analyzers: the NOVA 2 and the Orion SS-20. Samples were obtained from 43 human volunteers, 213 patients, and five dogs (106 samples). In the [Ca2+] range of 0.85 to 1.8 mmol/L, [Ca2+] measurements in whole blood with the NOVA 2 con...
[ 0.020584197714924812, 0.007641604635864496, 0.06674998253583908, 0.04865320399403572, -0.09157166630029678, -0.04991072416305542, -0.022923581302165985, 0.10039675980806351, 0.05334831401705742, 0.05056788772344589, -0.021066708490252495, -0.05383305251598358, -0.024760853499174118, 0.0513...
10,004,375
Gas-chromatographic/mass spectrometric detection of 3-hydroxy-3-methylglutaryl-CoA lyase deficiency in double first cousins.
[ -0.04535992816090584, -0.0555502288043499, -0.07141213119029999, -0.045716192573308945, 0.03409810736775398, 0.04928205534815788, -0.07781203836202621, 0.08834226429462433, -0.06367456167936325, -0.03663039207458496, 0.10234073549509048, -0.09968263655900955, -0.08039727807044983, 0.018050...
10,004,376
Gas chromatography/mass spectrometry was used for the detection of 3-hydroxy-3-methylglutaryl-CoA lyase (EC 4.1.3.4) deficiency in double first cousins. This enzyme is in the last step of leucine catabolism and is also involved in ketogenesis. Quantitation of urinary organic acids as their cyclohexyl esters demonstrate...
[ 0.0074405185878276825, -0.049539871513843536, -0.029609398916363716, -0.008852268569171429, -0.012393482960760593, 0.056265901774168015, -0.0700935572385788, 0.1188025027513504, -0.010898703709244728, -0.04852636158466339, 0.0031850109808146954, -0.056998930871486664, -0.03127696365118027, ...
10,004,377
Measurements of serum colloid osmotic pressure are of limited usefulness.
[ -0.030752522870898247, -0.09769057482481003, 0.02090446464717388, 0.012671520002186298, 0.026093807071447372, -0.07863909751176834, 0.0175012294203043, 0.11358490586280823, -0.020810246467590332, -0.0064853220246732235, -0.06650818884372711, -0.06803446263074875, -0.014541290700435638, 0.0...
10,004,378
We examined the usefulness of serum colloid osmotic pressure measurement in patients with chronic rather than acutely occurring low serum protein concentrations. We used two oncometers, the IL 186 Weil Oncometer and the Wescor Model 4100; results from the two instruments were interchangeable. Values for the colloid osm...
[ -0.014667270705103874, -0.09119106084108353, 0.03685765340924263, 0.04887217655777931, 0.05383416637778282, -0.053363051265478134, 0.014119070954620838, 0.1858997344970703, 0.03128928318619728, -0.06498545408248901, -0.053402096033096313, -0.003821220714598894, 0.017373621463775635, 0.0640...
10,004,379
Two serum pancreatic isoamylase determinations compared.
[ 0.07572416216135025, -0.07489579170942307, -0.0658475011587143, -0.020315809175372124, 0.029415100812911987, 0.017035523429512978, 0.03769057244062424, 0.03307046741247177, 0.019990595057606697, -0.04369330406188965, -0.01870936155319214, -0.01487121544778347, -0.05854935571551323, 0.04340...
10,004,380
Serum pancreatic isoamylase activity was measured by a method involving inhibition of salivary isoamylase and by a well-known agarose electrophoretic method, modified by us. We saw changes in electrophoretic patterns of pancreatic isoamylase fractions after storage of serum samples for three weeks at 4-8 degrees C, but...
[ 0.0516628660261631, -0.06906898319721222, -0.028522830456495285, -0.02016592025756836, 0.021936466917395592, -0.006091145798563957, 0.048333022743463516, 0.027965769171714783, 0.03901375085115433, -0.038358770310878754, 0.0016987391281872988, -0.04545564949512482, -0.05787070468068123, 0.0...
10,004,381
Turnover rate of skeletal alkaline phosphatase in humans.
[ -0.020031526684761047, -0.011086873710155487, -0.0019346551271155477, -0.037993717938661575, -0.0362156443297863, -0.01651630364358425, 0.023614129051566124, 0.04459776356816292, -0.004586034920066595, 0.08111365884542465, -0.010695522651076317, 0.032096780836582184, -0.010399149730801582, ...
10,004,382
Two patients with Paget's disease of bone were subjected to plasmapheresis. Alkaline phosphatase activities of serum declined sharply, but returned to preplasmapheresis values within eight to 10 days. The biological half-life of circulating skeletal alkaline phosphatase, as calculated from these experiments, is between...
[ -0.113561250269413, 0.008378894999623299, 0.024557659402489662, -0.0401107519865036, -0.06049361452460289, -0.027772367000579834, -0.06550903618335724, 0.10583855211734772, -0.031860269606113434, 0.07460704445838928, 0.00910861138254404, 0.02646545320749283, 0.034083154052495956, 0.0410916...
10,004,383
Stability of frozen liquid control sera for assay of cholesterol in high-density lipoprotein.
[ -0.03542549908161163, -0.14646945893764496, -0.06254785507917404, 0.013988587073981762, -0.02418532967567444, 0.03401960805058479, -0.029936114326119423, 0.06177280843257904, 0.007986793294548988, -0.07534950226545334, -0.01735304854810238, 0.0702071264386177, -0.009387364611029625, -0.036...
10,004,384
Liquid serum pools with low-, normal-, or above-normal concentration of high-density lipoprotein cholesterol were prepared by selection and dilution of sera having low lipoprotein content or by enrichment with concentrated high-density lipoprotein. Stability of the serum pools depended on storage conditions. On storage...
[ -0.021006407216191292, -0.07134370505809784, -0.07695554196834564, -0.03635290637612343, 0.03128550574183464, -0.040800947695970535, -0.00034348719054833055, 0.09905905276536942, -0.0026779212057590485, -0.07093591243028641, 0.035281985998153687, 0.003129640594124794, -0.008762196637690067, ...
10,004,385
Evaluation of a new serum separator.
[ -0.02034369856119156, -0.06350404024124146, -0.04546701908111572, -0.0455998070538044, 0.03806468844413757, -0.041884128004312515, -0.006689457688480616, 0.08379849046468735, -0.004934138618409634, -0.036503106355667114, 0.009472310543060303, -0.06842029839754105, -0.04544704034924507, 0.0...
10,004,386
We tested the Centri-Sep filter (DADE) for its effectiveness in separating serum from clotted blood samples used for chemical analysis. Although statistical analysis by paired t-test showed differences in results for some analytes with the use of this device as compared with use of no separator or of a serum-decanting ...
[ -0.025299305096268654, -0.028128616511821747, -0.024799451231956482, -0.0984107106924057, 0.0630233883857727, -0.04423946887254715, 0.004492671694606543, 0.08937761932611465, 0.02121007815003395, -0.05946032702922821, -0.015414628200232983, -0.06235174089670181, -0.026380445808172226, 0.05...
10,004,387
Proteins of human urine. II. Identification by two-dimensional electrophoresis of a new candidate marker for prostatic cancer.
[ -0.024842359125614166, -0.01631235145032406, -0.023395217955112457, -0.0749063566327095, 0.0907055214047432, -0.0403272770345211, 0.057569749653339386, 0.10159263759851456, 0.056986257433891296, -0.03501715138554573, 0.02719072252511978, -0.018579402938485146, -0.032174039632081985, 0.1065...
10,004,388
A protein series common to the urine and prostatic tissue of 16 of 17 patients with prostatic adenocarcinoma has been identified by high-resolution two-dimensional gel electrophoresis. These proteins, designated PCA-1, have a relative molecular mass in sodium dodecyl sulfate of about 40000. Analyses of urines from eigh...
[ -0.0495784766972065, -0.007872285321354866, 0.007973217405378819, -0.05334143713116646, -0.0251343734562397, -0.05432834103703499, 0.0691237822175026, 0.076324962079525, 0.04902259632945061, -0.030425842851400375, -0.000975271628703922, -0.006610387470573187, -0.010816802270710468, 0.07499...
10,004,389
Immunoinhibition and automated column chromatography compared for assay of creatine kinase isoenzyme MB in serum.
[ 0.015075039118528366, -0.030183935537934303, -0.09835176914930344, -0.018723690882325172, -0.009514350444078445, -0.0649215430021286, 0.024387085810303688, 0.1206902489066124, -0.052764784544706345, 0.005598164163529873, 0.0070069520734250546, -0.08443683385848999, 0.036486122757196426, 0....
10,004,390
We examined sera from six different groups of patients for CK-MB activity by means of two commercially available tests, an immunoinhibition method (E. Merck) and the CK-MB test as used with the aca (Du Pont). In the first group of patients (suspicion of myocardial infarction) the correlation between the two methods was...
[ 0.008424283936619759, -0.0283817145973444, -0.007013148162513971, 0.022260569036006927, -0.038991063833236694, -0.027663221582770348, 0.06635607779026031, 0.10762287676334381, 0.06814460456371307, 0.012293814681470394, -0.019824687391519547, -0.04317053407430649, 0.04179241880774498, -0.00...
10,004,391
Potentiometric analysis for sodium and potassium in biological fluids.
[ 0.009605496190488338, -0.03735104575753212, 0.04493020847439766, -0.03322809562087059, -0.054833054542541504, 0.06650615483522415, -0.0017025129636749625, 0.03739812597632408, 0.05016399174928665, -0.021525578573346138, -0.03468523919582367, -0.04706607013940811, 0.009147991426289082, 0.06...
10,004,392
Results obtained with a potentiometric analyzer, NOVA 1, specific for sodium and potassium, were compared with those by flame photometry. Both instruments showed linearity within a physiological range of sodium and potassium concentrations and had similar precisions. Volume displacements from addition of albumin or Int...
[ 0.0036216718144714832, -0.052883464843034744, 0.08713001757860184, 0.019179105758666992, -0.08860314637422562, 0.0002261768386233598, 0.022685065865516663, 0.04379923269152641, 0.06618157029151917, -0.040151000022888184, -0.07583405077457428, -0.019164934754371643, -0.005714374594390392, 0...
10,004,393
Fluorometry of selenium in serum or urine.
[ 0.09643012285232544, -0.03725510090589523, -0.03762173280119896, 0.04193127900362015, -0.007804868742823601, -0.10006100684404373, 0.06619011610746384, 0.12290585041046143, -0.008731645531952381, -0.10554813593626022, -0.005091196857392788, -0.05936211720108986, 0.06398167461156845, 0.0198...
10,004,394
This fluorometric procedure for determining selenium in human serum or urine is sensitive (requiring only 0.4 mL of sample), accurate, simple, and can be performed on several samples concurrently. Using this technique, we found a mean selenium concentration in the serum of normal Canadian men of 142.9 (SD 16.1) microgr...
[ 0.1488884836435318, -0.02758375182747841, -0.019431937485933304, 0.004480274859815836, -0.018060244619846344, -0.09149131178855896, 0.06223466992378235, 0.11256681382656097, -0.018268218263983727, -0.10585624724626541, -0.03291892632842064, -0.05473363399505615, 0.026097239926457405, 0.016...
10,004,395
Radioimmunoassay and chemical ionization/mass spectrometry compared for plasma cortisol determination.
[ 0.09383362531661987, 0.04021508991718292, -0.021473979577422142, 0.07878442108631134, -0.022673463448882103, 0.07268562912940979, 0.07673122733831406, 0.04817754402756691, -0.0035175473894923925, 0.03980965539813042, -0.019549479708075523, -0.03869779407978058, -0.04411425068974495, 0.0548...
10,004,396
We describe a method for determination of cortisol in plasma and urine, based on chemical ionization/mass spectrometry with deuterium-labeled cortisol as the internal standard. The within-run precision (CV) was 2.5-5.7%, the between-run precision 4.6%. Results by this method were compared with those by a radioimmunolog...
[ 0.05662253126502037, 0.01751238852739334, -0.028187982738018036, 0.04902100935578346, 0.010512382723391056, 0.012141644954681396, 0.00029229364008642733, 0.09610266983509064, -0.04930702969431877, -0.009314515627920628, -0.04005812108516693, -0.044513553380966187, -0.06887317448854446, 0.0...
10,004,397
Comparison of enzyme-linked immunosorbent assay and radioimmunoassay for prostate-specific acid phosphatase in prostatic disease.
[ 0.005741731263697147, 0.01928265392780304, -0.11081637442111969, -0.033038247376680374, 0.03122212551534176, 0.004707919433712959, 0.03594150394201279, 0.1310437172651291, 0.006915609817951918, 0.05133107304573059, -0.03593138977885246, 0.03999762982130051, -0.002251008991152048, 0.1065857...
10,004,398
We compared results by an enzyme-linked immunosorbent assay (ELISA) with those by a standard radioimmunoassay (RIA) for detection and quantitation of prostate-specific acid phosphatase (EC 3.1.3.2) in serum. Control subjects, patients with benign prostatic hyperplasia, and patients in all four clinical stages of prosta...
[ -0.0034142895601689816, 0.023626230657100677, -0.085972860455513, -0.05234575644135475, 0.04302961379289627, -0.01581505872309208, 0.022275349125266075, 0.1190531849861145, 0.047653231769800186, 0.03102995827794075, -0.01216586958616972, 0.021462997421622276, -0.0032055338378995657, 0.0820...
10,004,399
Colorimetry of serum acetaminophen (paracetamol) in uremia.
[ 0.050788480788469315, -0.027596650645136833, -0.033995240926742554, -0.0147623959928751, -0.01387952920049429, 0.03215021640062332, 0.10069429874420166, 0.14519411325454712, 0.02980642579495907, -0.02478037029504776, -0.07380375266075134, -0.05155528336763382, 0.024930814281105995, 0.04887...