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Nitrous oxide decreases motility of human neutrophils in vitro.
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The effect of 80 per cent nitrous oxide on motility of human neutrophils obtained from six volunteers was studied in vitro. In every case, random migration through the pores of 3 micrometer-millipore filter paper, was reduced (mean value 16 per cent). Chemotaxis toward casein also was reduced in every case (mean value 22 per cent). These results contrast with a previous study in which mean rates of migration were found to increase following exposure to 2 per cent halothane.
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] |
10,000,902
|
Position-induced Horner's syndrome.
|
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] |
10,000,903
|
The duration of effect of maternally administered meperidine on neonatal neurobehavior.
|
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10,000,904
|
Acute tolerance to high-dose barbiturate treatment in patients with severe head injuries.
|
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10,000,905
|
Increasing the functional gauge on the side port of large catheter sheath introducers.
|
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] |
10,000,906
|
Endotracheal tube Ignition during laryngeal surgery with resectoscope.
|
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] |
10,000,907
|
Development of bronchial obstruction with secondary lobar emphysema during anesthesia.
|
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] |
10,000,908
|
Method of ephedrine administration and nausea and hypotension during spinal anesthesia for cesarean section.
|
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10,000,909
|
Assessment of risk factors related to the acid aspiration syndrome in pediatric patients-gastric ph and residual volume.
|
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] |
10,000,910
|
Cardiac arrest associated with tension pneumocephalus.
|
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] |
10,000,911
|
Asymptomatic smokers: ASA I or II?
|
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] |
10,000,912
|
Carcinogen bioassay of enflurane in mice.
|
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] |
10,000,913
|
A carcinogen bioassay of enflurane was performed in Swiss/ICR mice. Two groups of weanling mice, each of 125 males and 125 females, were exposed to eigher a maximum tolerated dose of enflurane, 3000 ppm (0.3 per cent v/v) or compressed air for 4 hs per day, 5 days per week. After 52 weeks exposure, 25 males and 25 females from each group were killed. After 78 weeks exposure, a 4-week period without treatment was allowed before the remaining mice were killed. Mice killed at the scheduled periods and those killed or dying at other times throughout the study, underwent extensive gross and histologic, examinations unless autolysis or cannibalism precluded examination. After 78 weeks exposure, male mice in the enflurane-treated group had a 36 per cent incidence of liver tumors compared with 24 per cent in the control group; however, the difference was no statistically significant. The incidence of lung tumors was about 20 per cent in all groups. Other neoplastic lesions occurred in small numbers and were unrelated to treatment. It was concluded that under the conditions of the present experiment, chronic administration of enflurane at its maximum tolerated dose did not lead to an increased incidence of neoplasia in Swiss/ICR mice.
|
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10,000,914
|
Nosocomial septicemia due to multiply antibiotic-resistant Staphylococcus epidermidis.
|
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10,000,915
|
Thirteen episodes of Staphylococcus epidermidis sepsis occurred over a 20-month period in 11 patients receiving general surgical and medical care. These episodes were characterized by fever, toxicity, multiple positive blood cultures, and uniformly colonized intravascular catheters. An additional 16 patients had possible sepsis. Four associated deaths occurred; all three patients autopsied had multiple pulmonary abscesses in which gram-positive cocci were profusely present. In individual patients, prolonged episodes of septicemia were confirmed by multiple blood culture isolates of S. epidermidis, identical in antibiotic resistance pattern, phage type, and biotype. A prominent feature of the S. epidermidis isolates was resistance to many commonly used antimicrobial agents. Case-control studies and review of laboratory records indicated a significant association between multiply resistant S. epidermidis blood isolates and prolonged hospitalization and parenteral hyperalimentation. Most of these patients were hospitalized in the intensive care unit; nose and hand cultures taken from the personnel showed frequent carriage of multiply resistant S. epidermidis Staphylococcus epidermidis associated with intravascular devices may produce life-threatening bloodstream infections.
|
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10,000,916
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The distinction between cost and charges.
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10,000,917
|
The literature on economic efficiency in providing hospital services has been growing recently. Often such literature examines the costs of providing services at varying volumes of treatments per location per year. However, instead of measuring cost directly, these studies use patient bills (charges) aa a proxy for cost. Charges may bear little resemblance to economic cost, and use of charges as a proxy for economic cost may lead researchers to draw unwarranted conclusions about economic efficiency. Because of the differences between economic cost, accounting cost, and charges to the patient, actual resource consumption should be used as a measure of cost.
|
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] |
10,000,918
|
Methicillin-resistant Staphylococcus aureus. Epidemiologic observations during a community-acquired outbreak.
|
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] |
10,000,919
|
Infection with strains of methicillin-resistant Staphylococcus aureus occurred in 40 patients at time of admission to a large urban hospital from March to December 1980. Community-acquired methicillin-resistant S. aureus infections occurred in 24 drug abusers and 16 nonabusers. Patients with infections had a longer mean hospitalization and previously had received antimicrobial therapy more frequently than control subjects. Drug abusers with infections had been treated with cephalosporins more often than control subjects (P less than 0.05). Phage typing of 32 isolates showed that 21 were linked by a common phage type (29/52/80/95). Transmission of methicillin-resistant S. aureus from community-acquired cases occurred in the hospital. By January 1981, methicillin-resistant S. aureus accounted for 30.6% of nosocomial S. aureus infections at Henry Ford Hospital. Methicillin-resistant S. aureus infection may arise in the community as well as in the hospital and has the potential to disseminate in both settings.
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] |
10,000,920
|
HLA-B27 in 1982: reappraisal of a clinical test.
|
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] |
10,000,921
|
Intracoronary thrombolysis for acute myocardial infarction.
|
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10,000,922
|
Prevention of fatal bacterial infection in patients with anatomic or functional asplenia.
|
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] |
10,000,923
|
Hepatitis B transmission from dental personnel to patients: unfinished business.
|
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] |
10,000,924
|
Alcohol and mortality.
|
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] |
10,000,925
|
Vinblastine for autoimmune hemolytic anemia.
|
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] |
10,000,926
|
Polycythemia vera and alkylating agents.
|
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10,000,927
|
Splenectomy in Felty's syndrome.
|
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10,000,928
|
Bolous of methylprednisolone for aplastic anemia.
|
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10,000,929
|
Immune globulin for intravenous infusion.
|
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] |
10,000,930
|
Impotence in progressive systemic sclerosis.
|
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] |
10,000,931
|
Chorea and cimetidine.
|
[
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10,000,932
|
Complete heart block and the HLA system.
|
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] |
10,000,933
|
Computed tomography and psychiatric disorders.
|
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] |
10,000,934
|
Clinical outcomes after inferior myocardial infarction.
|
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] |
10,000,935
|
We studied the clinical outcomes of 46 patients followed prospectively for the initial 6 months after inferior infarction. Twenty-one patients (Group A) had no anterior ST depression (V2 to V4) present during the acute phase of the inferior infarction, whereas 25 patients (Group B) had such findings transiently. Although the clinical course during hospitalization was similar in the two groups, that after discharge differed. Only one of 21 patients in Group A had exertional angina and none had rest angina during follow-up; no infarcts or deaths occurred. In contrast, 15 patients in Group B had exertional angina; 12 also had rest pain (p less than 0.001, exact probability test). Two patients had reinfarction, one of whom died, and one sudden death also occurred. Of 15 patients in Group B who had cardiac catheterization, only eight had significant lesions in the anterior vessels, whereas seven did not; six of the seven patients became asymptomatic during follow-up without surgical therapy. Thus, electrocardiograms taken during the early phases of inferior myocardial infarction may be a valuable tool to recognize patients likely to have further ischemic symptoms during the early follow-up period.
|
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] |
10,000,936
|
Osteomalacia after parathyroidectomy in patients with uremia.
|
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] |
10,000,937
|
Five patients on maintenance dialysis had symptoms of osteomalacia, proven by biopsy, after parathyroidectomy. In all five patients clinical and radiographic manifestations of secondary hyperparathyroidism were present before surgery, and in two patients preoperative biopsy of bone confirmed the existence of osteitis fibrosa. Like previously described patients with osteomalacia all five had multiple fractures and normal or high serum calcium concentrations that rose to abnormally high values on treatment with vitamin D or dihydrotachysterol. Quantitative histomorphometry of biopsy after parathyroidectomy showed no residual parathyroid hormone effect and nearly complete cessation of mineralization. Four patients had forearm autografts of parathyroid tissue that appeared to be functioning at very low rates according to paired venous sampling, and all five patients had relatively low circulating concentrations of parathyroid hormone. This and earlier experiences reported by others suggest that secondary hyperparathyroidism may have an important facilitative role in the mineralization of bone in uremic patients.
|
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10,000,938
|
Splenic atrophy in systemic lupus erythematosus.
|
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] |
10,000,939
|
Five of 70 patients with systemic lupus erythematosus seen over a 5-year period had peripheral blood films suggestive of hyposplenism. Technetium-99m-sulfur colloid scans showed no splenic activity in three patients. One of these three patients, who had a spontaneous remission of persistent thrombocytopenia concurrent with the appearance of functional asplenia, had splenic atrophy shown by computed tomography; a second patient, who died of pneumococcal septicemia, was shown to have splenic atrophy with lymphocyte depletion at autopsy. The development of functional asplenia in the third patient has now, to date, had any obvious effect on her disease. In the two patients with normal scans, blood film findings returned to normal with treatment of the underlying disease. Polyvalent pneumococcal vaccine is recommended for patients with lupus erythematosus who have splenic atrophy.
|
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10,000,940
|
Functional hyposplenia after splenic irradiation for Hodgkin's disease.
|
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10,000,941
|
We previously reported a patients who developed fulminant pneumococcal sepsis 12 years after successful treatment for Hodgkin's disease, which included splenic irradiation. We have since evaluated splenic size and function in 25 patients who had received splenic irradiation 5 to 16 years previously either for Hodgkin's disease (n = 19) or non-Hodgkin's lymphoma (n = 6). Mean maximum splenic diameter as measured on a 99mTc-sulfur colloid liver-spleen scan was 6.2 cm in the irradiated group and 9.7 cm in a control group (p less than 0.001). The mean percentage of erythrocytes containing pits when observed with interference phase microscopy was 13.0% in the irradiated group, which was significantly different (p less than 0.001) from the levels found in each of the control groups: normal subjects, 0.9%; unstaged and untreated lymphoma patients, 0.6%; and patients after splenectomy, 33.7%. Patients who have had splenic irradiation should be considered at risk of developing overwhelming pneumococcal sepsis.
|
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] |
10,000,942
|
Comparison of 30- and 50-mCi doses of iodine-131 for thyroid ablation.
|
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10,000,943
|
We compared the utility of lower (30 mCi) and higher (50 to 60 mCi) doses of 131I used to ablate residual thyroid tissue after thyroidectomy for carcinoma. Whole body scans were done using 1 mCi 131I, 3 weeks after withdrawal of triiodothyronine. Patients had received ablation therapy within 3 days after scanning, and one or more subsequent scans were analyzed. Forty-eight patients were treated to ablate residual thyroid tissue that was presumed to be normal. Among 18 patients given the lower dose of 131I as outpatients, 15 had successful ablation and three needed a second administration; all 30 patients treated with the higher dose had successful ablation. Seventeen additional patients, presumed to have residual cancer, received 50 to 150 mCi; and six needed treatment. Although 1 dose of 50 to 60 mCi 131I provides more ablation, use of the usually effective 30-mCi dose for initial ablation is justified by the convenience of outpatient administration, the lower expense, and the lower whole-body radiation dose.
|
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] |
10,000,944
|
Levothyroxine replacement dose for primary hypothyroidism decreases with age.
|
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] |
10,000,945
|
We studied 23 elderly (other than 65) and 44 younger ambulatory adult patients with primary hypothyroidism to ascertain the dose of levothyroxine needed for complete replacement in relation to age. The elderly patients (average age, 75.7 years) needed an average 118 microgram/d whereas the younger patients (average age, 48.1 years) needed 158 microgram/d. The data indicate that thyroxine requirement may decrease continuously with age. This decrease probably reflects the progressive decrease in thyroxine degradation rate that occurs with age.
|
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] |
10,000,946
|
Multiple cutaneous focal mucinoses with hypothyroidism.
|
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] |
10,000,947
|
A 54-year-old woman with myxedema had hundreds of discrete cutaneous mucinous papules, which responded dramatically to appropriate replacement therapy with L-thyroxine. Each lesion both clinically and histologically resembled a cutaneous focal mucinosis (cutaneous myxoma). Multiple cutaneous focal mucinoses are a previously undescribed manifestation of hypothyroidism that can be differentiated from other syndromes that have cutaneous mucinous deposits.
|
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] |
10,000,948
|
Hepatic veno-occlusive disease caused by 6-thioguanine.
|
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10,000,949
|
Clinically reversible veno-occlusive disease of the liver developed in a 23-year-old man with acute lymphocytic leukemia after 10 months of maintenance therapy with 6-thioguanine. Serial liver biopsies showed the development and resolution of intense sinusoidal engorgement. Although this disease was clinically reversible, some subintimal fibrosis about the terminal hepatic veins persisted. This case presented a unique opportunity to observe the histologic features of clinically reversible hepatic veno-occlusive disease over time, and may be the first case of veno-occlusive related solely to 6-thioguanine.
|
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10,000,950
|
Nifedipine in the treatment of achalasia.
|
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] |
10,000,951
|
Lithium-induced hyperparathyroidism: an alteration of the "set-point".
|
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] |
10,000,952
|
Growth of hormone and prolactin secretion by a tumor of the pharyngeal pituitary.
|
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] |
10,000,953
|
Systemic blastomycosis with associated diabetes insipidus.
|
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] |
10,000,954
|
Pulmonary hematoma secondary to anticoagulant therapy.
|
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] |
10,000,955
|
Diagnostic value of HLA-B27 testing ankylosing spondylitis and Reiter's syndrome.
|
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10,000,956
|
Typing for histocompatibility antigen (HLA)-B27 has been suggested as a clinically valuable diagnostic test for ankylosing spondylitis and Reiter's syndrome, although some decry its use for this purpose. Diagnoses can be made in most patients with these diseases on the basis of the history, physical examination, and roentgenographic findings. The B27 test cannot be used to screen an asymptomatic population to detect these diseases and should not be thought of as a routine diagnostic test. We present probability graphs derived from Bayes' theorem, which show that for certain patients the B27 test, when used properly, is of clinical value as an aid to diagnosis. Proper application of the B27 test in clinical medicine is discussed. The test result does not absolutely confirm or exclude the presence of these diseases; it merely provides a probability statement on their existence in the patient. The test is therefore most useful to physicians who understand the use of probability reasoning in clinical decision making.
|
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] |
10,000,957
|
The borderline personality in the medical setting.
|
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] |
10,000,958
|
Patients with a borderline personality disorder are notorious for causing problems in medical settings because of their angry, provocative, and often self-destructive behaviors. Such patients may frequently evoke negative, often angry responses in physicians. The diagnosis and effective management of such patients are discussed.
|
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] |
10,000,959
|
Aminoglutethimide as treatment of postmenopausal women with advanced breast carcinoma.
|
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] |
10,000,960
|
Hormone-dependent breast carcinomas respond to deprivation of biologically active estrogens with objectively quantifiable tumor regression. Aminoglutethimide, a known inhibitor of steroid synthesis, is also a potent blocker of the aromatase enzyme and, thus, of estrogen production. We developed an effective regimen to inhibit estrogen production in postmenopausal women using aminoglutethimide and replacement glucocorticoid. One hundred forty-seven women initially received aminoglutethimide and replacement glucocorticoid as treatment of metastatic breast carcinoma. One hundred twenty-nine women are currently evaluable for assessment of clinical and hormonal responses. Thirty-seven percent of unselected women and 49% of estrogen receptor-positive patients experienced objective tumor regression. Responses occurred predominantly in soft tissue (47%) and bone (35%) and lasted 30 +/- 9.1 months for complete and 14 +/- 1.5 months for partial regressions. Plasma and urinary estrogen levels fell equally in responder versus nonresponder groups whereas androgen levels declined less in patients with progressive disease.
|
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10,000,961
|
Meningovascular syphilis after 'appropriate' treatment of primary syphilis.
|
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] |
10,000,962
|
Meningovascular syphilis developed in a patient two years after the treatment of primary syphilis with a single intramuscular injection of 2.4 million units of penicillin G benzathine as recommended by the Centers for Disease Control. Although it could not be established with certainty whether this infection represented a reinfection or a treatment failure, the case emphasizes the necessity for serologic follow-up examination in all patients treated for primary syphilis.
|
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] |
10,000,963
|
Ptosis associated with iatrogenic pneumothorax: a false lateralizing sign.
|
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] |
10,000,964
|
Two cachectic, obtunded patients were seen with unilateral periorbital emphysema resembling ptosis as a primary manifestation of pneumothorax. Speculation is made as to the possible role of malnutrition in this unusual manifestation. Spontaneous pneumothorax should be considered in the obtunded patient with ptosis that is poorly explained by other neurologic findings.
|
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] |
10,000,965
|
Typhoid hepatitis with immunoglobulins and complement deposits in bile canaliculi.
|
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10,000,966
|
Documented typhoid fever in a 26-year-old patient was complicated by acute hepatitis with unusually profound jaundice. Liver biopsy revealed focal cell necrosis, mononuclear cell infiltration. Kupffer cell proliferation, and mild cholestasis. Immunofluorescent studies of the liver biopsy revealed deposits of IgG, IgA, IgM, and C3 in the bile canaliculi, suggesting a role for damage by immune complexes in typhoid hepatitis.
|
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] |
10,000,967
|
Acquired Pelger-Huët nuclear anomaly with tuberculosis.
|
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] |
10,000,968
|
Karel Pelger described an abnormality of granulocyte nuclear segmentation in the context of advanced tuberculosis, but G. Huët questioned this association. It is now recognized that the Pelger-Huët nuclear anomaly (PHNA) can be either hereditary or acquired with systemic diseases, commonly hematologic dysplasias. An association with tuberculosis has never been well verified. The man described in our study had cachexia, high fevers, severe hypoproliferative anemia, and acquired PHNA. At autopsy, an overwhelming tuberculosis was discovered in the absence of any other underlying disease. Acquired PHNA may serve as a diagnostic and prognostic indicator in tuberculosis.
|
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10,000,969
|
Nonketotic hyperglycemia appearing as choreoathetosis or ballism.
|
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-0.007615859154611826
] |
10,000,970
|
A number of focal neurologic abnormalities may accompany severe, nonketotic hyperglycemia, but extrapyramidal movement disorders have not previously been described. We evaluated the conditions of three patients with marked hyperglycemia in whom hemichorea or ballism developed that resolved completely with normalization of the blood glucose level. Potential pathogenetic mechanisms include relative dopaminergic hypersensitivity, impaired synthesis of acetylcholine or gamma-aminobutyric acid, or an undefined effect of hyperosmolarity, perhaps unmasking a previously subclinical lesion of the basal ganglia. Serum glucose level should be determined in anyone with the new onset of choreoathetosis or ballism, as hyperglycemia is a rapidly reversible cause of these conditions.
|
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] |
10,000,971
|
Simultaneous medullary sponge and adult polycystic kidney disease: the need for accurate diagnosis.
|
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] |
10,000,972
|
Two cases of simultaneous medullary sponge and adult polycystic kidney disease developed in siblings. The diagnoses of polycystic kidneys were made by renal ultrasonography and medullary sponge kidney was diagnosed roentgenographically. The family history was markedly positive for "cystic" disease. Medullary sponge kidney might be a precursor of polycystic kidney disease in some instances, or, more likely, this represents two separate afflictions occurring in the same individuals. When large medullary sponge kidneys are encountered, the possibility of concomitant polycystic kidney disease should be entertained and investigated with a sonogram. While the prognosis of isolated sponge kidney is excellent, polycystic kidney disease eventually leads to hypertension and renal failure.
|
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] |
10,000,973
|
Sulindac-induced aseptic meningitis.
|
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] |
10,000,974
|
A 22-year-old woman with systemic lupus erythematosus experienced generalized pruritus, shortness of breath, pleuritic chest pain, visual blurring, severe photophobia, a stiff neck, an occipital headache, and a temperature of 39.4 degrees C within one hour after taking sulindac (Clinoril). Findings from a CSF examination disclosed a notable elevation of protein and a polymorphonuclear pleocytosis. All symptoms disappeared within 24 hours. Inhibition of prostaglandin synthesis did not seem to be the mechanism of this adverse reaction, since the patient tolerated aspirin.
|
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] |
10,000,975
|
Cimetidine-associated exacerbation of cutaneous lupus erythematosus.
|
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] |
10,000,976
|
A patient with systemic lupus erythematosus (SLE) had new LE skin lesions develop following the initiation of cimetidine, a drug that is known to influence a variety of cellular functions. The temporal relationship between the onset of cutaneous LE with the ingestion of cimetidine is reported to alert others to the possibility that this H2 receptor antagonist may exacerbate cutaneous disease activity in patients with LE.
|
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] |
10,000,977
|
Raised serum alkaline phosphatase activity in one family.
|
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] |
10,000,978
|
Eleven members of the same family were studied after an incidental detection of raised serum alkaline phosphatase activity in one of them without any apparent underlying cause. Three other members were found to have the same abnormality; none of them had an associated disease. In the four cases with elevated serum alkaline phosphatase levels, its activity showed a preponderance of the bone isoenzyme. Studies of the erythrocyte and histocompatibility antigens in nine members of the family, as well as idiograms of karyotypes of four of them, did not show any relation between histocompatibility antigens and the raised levels of serum alkaline phosphatase. Also, no chromosomal abnormality is shown from karyotypes. The data suggest a probable autosomal dominant pattern of inheritance.
|
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10,000,979
|
Coronary artery spasm appearing as syncope.
|
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] |
10,000,980
|
A 56-year-old man had coronary artery spasm. The initial manifestation of the disease was syncope that occurred at night. Coronary artery spasm was documented by Holter recording and cardiac catheterization. The patient was effectively treated with nitrates and calcium-blocking agents.
|
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] |
10,000,981
|
Prediction of satisfactory response to pleural sclerosis using radiopharmaceuticals: study in a patient with cirrhotic hydrothorax and LeVeen shunt.
|
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] |
10,000,982
|
Rapidly recurring right pleural effusion was a disabling clinical problem in a 51-year-old woman with alcoholic cirrhosis that had not been relieved by diuretic therapy or a LeVeen shunt. By injecting technetium Tc 99m albumin aggregated into the peritoneal cavity, shunt patency and rapid flow into the pleural effusion were demonstrated. In contrast, technetium Tc 99m albumin aggregated injected injected into the pleural fluid showed no movement into the abdominal cavity. These test results predicted that pleural sclerosis would help her clinical problem but would not place the abdominal contents in jeopardy. This prediction has proved to be correct.
|
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] |
10,000,983
|
Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease.
|
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] |
10,000,984
|
Coccidia were found in a patient suffering from malabsorption syndrome. In addition, immunologic investigation showed combined humoral and cellular immunodeficiency. Treatment with metronidazole induced the disappearance of coccidia from the stool and clinical remission. Six months later, the patient was seen with acute lymphoproliferative disease and died thereafter. The possible relationship between malabsorption, immunodeficiency, coccidiosis, metronidazole, and malignancy is reviewed.
|
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10,000,985
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Computed tomographic scan.
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] |
10,000,986
|
The manufacture of digitalis.
|
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10,000,987
|
Erroneous C-peptide values given?
|
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] |
10,000,988
|
Treating paroxysmal supraventricular tachycardia.
|
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] |
10,000,989
|
Paraquat and lipid peroxidation.
|
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10,000,990
|
Prevention of influenza-related morbidity and mortality.
|
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] |
10,000,991
|
Primary care rheumatology.
|
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] |
10,000,992
|
What role rheumatology?
|
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] |
10,000,993
|
Diagnostic problem in acute myocardial infarction: CK-MB in the absence of abnormally elevated total creatine kinase levels.
|
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] |
10,000,994
|
Seven hundred twenty-four consecutive patients admitted to a coronary care unit for chest pain underwent comparative evaluation of ECG and lactic dehydrogenase (LDH) and creatine kinase (CK) enzyme and isoenzyme patterns. Of the 724 patients, 419 (58%) had the myocardial component (MB) of CK detected; however, 69 (16%) of the latter had no abnormal elevation of total CK levels. This group with CK-MB but persistently normal total CK levels demonstrated fewer diagnostic QRS changes on ECG (17% vs 54%) and a lower incidence of LDH 1:2 inversion (28% vs 79%) than did the group with CK-MB and abnormally elevated total CK levels. However, no specific level of either total CK or CK-MB could segregate the patients with QRS or LDH level changes, which suggests that persistently normal levels of CK do not exclude the diagnosis of myocardial infarction. Evidence that myocardial necrosis can occur in the absence of an abnormal elevation of total CK levels is confirmed histologically in one patient.
|
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] |
10,000,995
|
Criteria for early discharge after acute myocardial infarction: validation in a community hospital.
|
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] |
10,000,996
|
All patients admitted to a community hospital coronary care unit during an 18-month-period were studied to validate previously reported criteria for early hospital discharge after myocardial infarction. Factors present during the first four hospital days, which predict subsequent complications requiring urgent medical attention, were classified as either urgent or prognostic. Patients whose initial four days were marked by either no complications (81 patients) or prognostic complications (51 patients) are described. Only one patient in the group of 81 patients had a subsequent urgent complication. Four of 55 patients had late urgent complications. Persistent sinus tachycardia occurred during the first four days in all four of these 55 patients. Early hospital discharge would be feasible in the group with neither urgent nor prognostic complications. Further study of persistent sinus tachycardia is required to improve its predictive ability.
|
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] |
10,000,997
|
Relationship between sex hormones, myocardial infarction, and occlusive coronary disease.
|
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] |
10,000,998
|
An alteration in sex hormones has been considered a risk factor for myocardial infarction. In this study, estradiol (E2) and testosterone (T) levels were evaluated in healthy firefighters, patients with myocardial infarction acutely and during their convalescence, patients with no evidence of occlusive coronary artery disease on arteriography, and patients with chronic angina pectoris in whom there was at least one vessel that indicated 50% occlusive coronary artery disease. Although T levels were similar in all groups, E2 levels were substantially higher in patients with myocardial infarction and in patients with chronic angina pectoris. These results support the hypothesis that elevated estrogen levels may be a risk factor for myocardial infarction and coronary artery disease, possibly by promoting clotting or coronary spasm.
|
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] |
10,000,999
|
Hepatitis B virus in patients undergoing hemodialysis: transmission risks and psychosocial reactions.
|
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