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10,001,100 | Impaired gastric emptying in gastric ulcer patients has generally been explained by gastric hypomotility. The gastric motor response to an electrical vagal stimulus was measured intraoperatively in patients with gastric ulcers (GU, n = 21), duodenal ulcers (DU, n = 25) and combined ulcers (GDU, n = 6). Amplitude and du... | [
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10,001,101 | The effect of altered luminal nutrition on cellular proliferation and plasma concentrations of enteroglucagon and gastrin after small bowel resection in the rat. | [
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10,001,102 | Luminal nutrition is known to have a trophic effect on small bowel mucosa after intestinal resection. Humoral agents, however, may also contribute to this process. Two of the proposed humoral agents, enteroglucagon and gastrin, were therefore investigated after intestinal resection and transection in the rat, and chang... | [
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10,001,103 | A comparison of circular stapling devices in colorectal anastomoses. | [
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10,001,104 | The short term results of colorectal anastomosis using the Russian SPTU and American EEA circular staplers are compared. Anastomoses with these stapling devices were attempted in 61 patients between October 1978 and December 1980. In 1 patient the stapling method failed at operation, so that 60 patients had a stapled a... | [
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10,001,105 | Trophic effect of short chain fatty acids on mucosal handling of ions by the defunctioned colon. | [
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10,001,106 | Sodium and water absorption were measured in defunctioned loops of colon of dogs either in the presence or in the absence of the bacterial fatty acid, n-butyrate. In freshly defunctioned colonic loops n-butyrate enhanced sodium absorption twofold (P less than 0.05) and promoted sodium absorption for 48 h. In the absenc... | [
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10,001,107 | Hospital admissions for acute cholecystitis: changes in the age and sex distribution in Oxford in the post-war period. | [
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10,001,108 | Admissions for acute cholecystitis to the Radcliffe Infirmary, Oxford, during the period 1974-1978 have been reviewed and compared with figures previously published for the period 1953-1962 (1). There was a small overall increase in the annual rate of female admissions for acute cholecystitis between the two periods an... | [
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10,001,109 | Neurovascular traction injuries of the upper limb root. | [
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10,001,110 | Eight cases of injury to the subclavian and axillary arteries are described. All were accompanied by injury to the brachial plexus. Arterial continuity was restored in all cases. Six young patients sustained high velocity injuries and they showed no neurological improvement. Two elderly patients with low velocity injur... | [
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10,001,111 | The effect of sustained venous hypertension on the skin capillaries of the canine hind limb. | [
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10,001,112 | An increased number of skin capillaries has been found in human skin subjected to sustained venous hypertension. To investigate this observation, venous hypertension was produced in the hind limb of Greyhounds by fashioning an arteriovenous (AV) fistula between the femoral vessels. This caused an increase in the number... | [
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10,001,113 | Carotid artery occlusion following endarterectomy: evaluation by spectral analysis of Doppler ultrasound signals. | [
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10,001,114 | The clinical results of carotid endarterectomy are well documented, but there is little objective information on the incidence of postoperative occlusion. We have studied the postoperative patency of the internal and external carotid arteries using continuous wave Doppler ultrasound with spectral analysis (Spectrascrib... | [
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10,001,115 | Difficulties in the diagnosis and management of pyogenic liver abscess. | [
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10,001,116 | Thirty patients with pyogenic liver abscess were admitted to King's College Hospital between 1967 and 1978. The overall mortality was 43 per cent (13 patients). The diagnosis was often difficult and in 10 patients the correct diagnosis was not made until post-mortem. Of the 20 patients diagnosed and treated, 17 had a u... | [
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10,001,117 | Stenosis of the common bile duct in chronic pancreatitis. | [
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10,001,118 | The incidence of common bile duct stenosis in patients with chronic pancreatitis was studied in a consecutive series of patients admitted for endoscopic retrograde cholangiopancreatography (ERCP). Thirty-six out of 79 patients (46 per cent) with moderate or advanced chronic pancreatitis as defined by radiological crite... | [
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10,001,119 | Delayed presentation of small intestine damage due to closed abdominal trauma. | [
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10,001,120 | Use of the t test in the British Journal of Surgery. | [
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10,001,121 | Toxic dilatation complicating fulminant amoebic colitis. | [
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10,001,122 | Late results of proximal gastric vagotomy without drainage for duodenal ulcer: 5--9-year follow-up. | [
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10,001,123 | From 1970 to 1974 proximal gastric vagotomy without drainage was performed in 158 patients for duodenal ulcer. One patient died, giving an operative mortality of 0.6 per cent. Nine unrelated deaths occurred during the period of survey and 5 other patients were lost to follow-up. The remaining 143 patients were followed... | [
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10,001,124 | [Eye drug therapy. Principles and practice]. | [
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10,001,125 | Extremity lesions in the Intergroup Rhabdomyosarcoma Study (IRS-I): a preliminary report. | [
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10,001,126 | The sites in which rhabdomyosarcoma occurs most frequently in children and young adults are the head and neck, genitourinary tract, and the extremities. Among these three sites, tumors of the extremities have been associated with the highest relapse rate and lowest survival rate in patients treated by protocols of the ... | [
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10,001,127 | Malignant mesothelioma of the tunica vaginalis testis: report of first case with preoperative diagnosis. | [
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10,001,128 | The cytologic, histologic and ultrastructural features of a malignant carcinomatous mesothelioma of the tunica vaginalis testis in a 30-year old patient are described. This is the first such case with preoperative diagnosis by cytologic examination of hydrocele fluid and the second with documented history of exposure t... | [
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10,001,129 | Neuromuscular hamartoma--a benign "triton tumor" composed of mature neural and striated muscle elements. | [
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10,001,130 | Two infants with benign, hamartomatous tumors composed of well-differentiated and intimately admixed neural and striated muscle components are presented. Their histogenesis is discussed in light of embryologic concepts of the derivation of mesenchymal tissues from neuroectoderm and in reference to previous reports of b... | [
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10,001,131 | Tumors of the cerebral aqueduct. | [
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10,001,132 | Two cases of tumor of the cerebral aqueduct are described. Case 1 is a pilocytic astrocytoma in a 16-year-old girl with a two-year history of intermittent increase of intracranial pressure. The tumor was completely confined within the lumen of the aqueduct. Case 2 is a subependymoma of a 68-year-old man. The tumor exte... | [
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10,001,133 | Prognostic factors in nasopharyngeal malignancy. | [
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10,001,134 | Data collected from review of 99 patients with carcinoma of the nasopharynx was submitted for statistical analysis. The purpose of the analysis was to determine patient, tumor and treatment factors that influence survival. The only patient factor observed to influence survival was patient age (P = 0.05). Greatest survi... | [
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10,001,135 | Myosarcomas of the stomach: natural history, prognostic factors and management. | [
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10,001,136 | A retrospective study was made of 41 patients treated for gastric myosarcoma to identify prognostic factors that influence results. The adjusted five- and ten-year survival rates were 56% and 43% respectively, with no significant difference between leiomyosarcoma and malignant leiomyoblastoma. A histopathologic grade o... | [
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0.03576728329062462,
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0.0... |
10,001,137 | Effect of doxorubicin on liver regeneration and host survival after two-thirds hepatectomy in rats. | [
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0.070... |
10,001,138 | The effects of doxorubicin (Adriamycin) on regenerating liver were studied after two-thirds hepatectomy in rats. In Group I, standard two-thirds hepatectomy was performed. Doxorubicin in a dose of 2 mg/kg (Group II) and 6 mg/kg (Group III) was given intravenously immediately after the same hepatectomy. In Group IV, 6 m... | [
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0.0776434... |
10,001,139 | Relationship between patients' early recognition of melanoma and depth of invasion. | [
0.04263690114021301,
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0.04265... |
10,001,140 | The correlation between time to diagnosis and thickness of lesion in patients with superficial spreading melanoma was explored. Charts of 245 patients diagnosed since 1976 were reviewed for data on lesion duration and time since elevation (as perceived by patients); and the degree of elevation (if any); thickness, and ... | [
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10,001,141 | A pilot investigation of the psychologic functioning of patients with anticipatory vomiting. | [
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10,001,142 | A pilot investigation of nine cancer patients receiving chemotherapy on an outpatient basis at the University of Florida's Shands Teaching Hospital is reported. The focus of the study was comparing patients with anticipatory vomiting symptoms with patients who did not exhibit prechemotherapy vomiting on measures of aff... | [
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10,001,143 | Radiation therapy with or without primary limited surgery for operable breast cancer: a 20-year experience at the Marseilles Cancer Institute. | [
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0... |
10,001,144 | Since 1960 more than 3000 consecutive patients with operable infiltrating breast carcinoma were treated by radiation therapy with or without primary limited surgery, which usually consisted of local excision. For tumors smaller than or equal to 5 cm the ten-year crude survival rate is 77% for patients without palpable ... | [
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10,001,145 | Radiation-induced tumor regression as a prognostic factor in patients with invasive cervical cancer. | [
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10,001,146 | Radiation-induced tumor regression was evaluated as a prognostic factor in 200 patients with invasive cervical cancer treated at the University of Kentucky Center during the years 1973-1977. Radiation responses were classified as complete (Type A), intermediate (Type B), or incomplete (Type C) based upon pelvic examina... | [
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10,001,147 | Granulomas in melanoma patients treated with BCG immunotherapy. | [
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0.0027... |
10,001,148 | Autopsy slides from 22 melanoma patients who received bacille Calmette-Guérin BCG immunotherapy and who had a postmortem examination at the UCLA Center for the Health Sciences were examined for the presence of granulomas. Granulomas were found in six patients (29%) who received BCG but not in a group of 25 melanoma pat... | [
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10,001,149 | Sézary syndrome with a 14:14 (q12:q31) translocation. | [
0.01083175279200077,
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0.025883790105581284,
0.03570359945297241,
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0.0486... |
10,001,150 | The Sézary syndrome was diagnosed in a 71-year-old black woman with erythroderma, generalized lymphadenopathy and hepatosplenomegaly. The laboratory data revealed a white blood cell count of 65,000 mm3 with 81% lymphocytes, the majority having an indented or a cerebriform nucleus. The skin biopsy, the lymph node biopsy... | [
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-0.0... |
10,001,151 | LDH isoenzyme patterns in tumors, polyps, and uninvolved mucosa of human cancerous colon. | [
0.026345625519752502,
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0.004586843308061361,
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0.04134232550859451,
-0.05100283399224281,
-0.00787... |
10,001,152 | By using a method of electrophoresis separation, the authors determined the relative values of each one of the lactic dehydrogenase (LDH) isoenzymes in the normal colonic mucosa. In adenocarcinomas, there is a significant rise in the percent of LDH-5. A similar disturbance has been demonstrated in 14 polyps, which conf... | [
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0.06399787217378616,
0.040887780487537384,
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10,001,153 | Malignant intrathoracic oncocytoma. | [
-0.08734599500894547,
0.031972065567970276,
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0.07198788970708847,
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10,001,154 | A case of malignant intrathoracic oncocytoma occurring in a 56-year-old man is reported. Preoperative films of the chest showed a large superior mediastinal tumor. Radical excision through a right-sided thoracotomy was impossible because of the extensive growth. Light and electron microscopic findings revealed a malign... | [
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0.07820003479719162,
0.02... |
10,001,155 | Discriminant analysis of radiation therapy procedures: the Patterns of Care Process Survey for carcinoma of the larynx. | [
0.0926561951637268,
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0.025919189676642418,
-... |
10,001,156 | Discriminant analysis was applied to larynx data from the Patterns of Care Study (PCS) in order to evaluate and classify radiation therapy procedures. Since PCS has recorded information on a large number of separate procedures, a method was needed to treat them coherently. Discriminant analysis provided such a method t... | [
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0.08529920130968094,
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0.0... |
10,001,157 | Clear cell sarcoma and selective IgM deficiency: a case report. | [
-0.04606021195650101,
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0.010371827520430088,
0.03144493326544762,
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0.016112234443426132,
0.0371585... |
10,001,158 | A case of clear cell sarcoma of tendons and aponeuroses and a co-existent IgM deficiency is reported. The tumor arose in the Achilles tendon with metastases to the skin, bone, and lymph nodes. The tumor, examined by light and electron microscopy, consisted of glycogen-containing clear cells with melanotic and amelanoti... | [
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0.05700299143791199,
0.0174... |
10,001,159 | The in vitro effect of a calf thymus extract (thymostimulin) on the immunologic parameters of patients with untreated Hodgkin's disease. | [
-0.02380935288965702,
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0.07699175924062729,
-0.0152... |
10,001,160 | The in vitro effect of a calf thymus extract, thymostimulin (TP--1), on the E-rosette-forming capacity and on the PHA blastogenic response of peripheral blood lymphocytes was evaluated in 20 patients with untreated Hodgkin's disease. The mean percentage of lymphocytes forming E rosettes increased in patients from 44.2%... | [
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0.07375223189592361,
0.07775440812110901,
-0.013902... |
10,001,161 | Peripheral nerve sheath tumors: an electron microscopic study of 43 cases. | [
-0.03396192193031311,
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0.04104616120457649,
0.015039... |
10,001,162 | To obtain data concerning their histogenesis, 23 benign solitary schwannomas (including five cellular variants), 10 neurofibromas, and 10 malignant peripheral nerve sheath tumors were studied by electron microscopy. The results confirm previous findings that solitary schwannomas (so-called neurilemomas) are composed pr... | [
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0.018431246280670166,
0.05056577920913696,
0.... |
10,001,163 | Myoepithelial cell adenoma of the parotid gland: a light and ultrastructural study. | [
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0.033354826271533966,
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0.020728852599859238,
-0.040... |
10,001,164 | Light, histochemical, and ultrastructural features of a myoepithelial cell adenoma of the parotid gland are described. Ultrastructurally, the neoplasm was almost entirely composed of myoepithelium. The spindle-shaped myoepithelial cells and their processes were filled with longitudinally oriented myofilaments with char... | [
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0.022836485877633095,
-0.03562... |
10,001,165 | Morphology of adenocarcinoma in situ of the uterine cervix: a study of 14 cases. | [
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0.008490018546581268,
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10,001,166 | Fourteen cases of adenocarcinoma in situ (ACIS) of the cervix in patients 30 to 52 years old were studied. In its pure form (four cases, ACIS was discovered cytologically, but when associated with a squamous abnormality (ten cases), it was found histologically. Two different types of ACIS were distinguished both histol... | [
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0.08830278366804123,
-0.0096670... |
10,001,167 | Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: the value of chromosomal studies in predicting response and survival. | [
-0.02988312765955925,
0.01675066165626049,
0.009374545887112617,
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0.06977353245019913,
-0.045790862292051315,
-0.08280... |
10,001,168 | The responses of 23 patients with agnogenic myeloid metaplasia (AMM) to androgen therapy were studied. Various clinical and laboratory parameters were analyzed for their value in determining response to therapy and length of survival. Fifty-seven percent of patients responded, as determined by a sustained increase in h... | [
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10,001,169 | Self-healing reticulohistiocytosis: a clinical, histologic, and ultrastructural study of the fourth case in the literature. | [
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0.05770424008369446,
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0.02939... |
10,001,170 | A case of self-healing reticulohistiocytosis is reported. Our case differed from those previously reported in that tumors developed 17 days after birth (instead of at birth) and all tumors disappeared rapidly within three weeks (instead of two to three and one-half months). Hematologic abnormalities such as absolute ne... | [
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10,001,171 | Bone involvement in Hodgkin's disease. | [
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-0.0205... |
10,001,172 | Eighteen patients with osseous involvement were identified from a series of 124 consecutive patients treated with combined-modality therapy with advanced-stage or relapsing Hodgkin's disease. Multiple lesions were seen as frequently as were solitary lesions. Nodular sclerosing histology was as prevalent as mixed cellul... | [
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-0.02386932633817196,
0.11398370563983917,
0.06570661067962646,
-0.0... |
10,001,173 | Basal cell epithelioma (carcinoma) in children and teenagers. | [
0.007260006386786699,
0.09125614166259766,
-0.05716251581907272,
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0.029497448354959488,
-0.0283... |
10,001,174 | Among over 390,000 routine dermatopathologic specimens there were 85 cases diagnosed as basal cell epithelioma (carcinoma) (BCE) in persons 19 years old or younger. This number was refined to 40 cases de novo BCE in children and teenagers. Basal cell epithelioma unrelated to other conditions is rare in the young and it... | [
0.005720656365156174,
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0.10134701430797577,
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0.030404049903154373,
-0.022519189... |
10,001,175 | Glucose-6-phosphate dehydrogenase: a possible clinical indicator for prostatic carcinoma. | [
-0.080810546875,
0.024322926998138428,
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-0.011172582... |
10,001,176 | Any system of biochemical analysis that can be used to detect chemical differences between normal and malignant cells may add potentially valuable information to complement the histologic data which provide the practical definition of human prostatic carcinoma. A difference (P less than 0.0001) was observed in the leve... | [
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0.0056648459285497665,
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0.012033862061798573,
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... |
10,001,177 | Parathyroid carcinoma: a clinical study of seven cases of functioning and two cases of nonfunctioning parathyroid cancer. | [
-0.018618229776620865,
-0.01009316835552454,
-0.005291158799082041,
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0.08723165094852448,
0... |
10,001,178 | Seven cases of functioning and two cases of nonfunctioning parathyroid carcinoma are presented together with a general discussion of this disease. Functioning parathyroid carcinoma may be associated with prolonged survival. The morbidity and mortality from this disease are generally related to the prolonged hypercalcem... | [
0.023748865351080894,
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0.09613154828548431,
... |
10,001,179 | Benign clinical behavior of immature mediastinal teratoma in infancy and childhood: report of two cases and review of the literature. | [
0.09323395043611526,
0.053569771349430084,
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0.049279313534498215,
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-0.04641313478350639,
0.025876... |
10,001,180 | Germ cell tumors of the mediastinum can be divided into three categories: 1) mature teratomas which have all elements at a mature level; 2) immature teratomas which are similar to the mature teratomas, but also contain immature epithelial or mesenchymal elements or blastema; and 3) embryonal tumors which contains eleme... | [
0.06652764976024628,
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0.038127753883600235,
0.04149352386593819,
0.025628453120589256,
-0.021019645035266876,
0.0253306... |
10,001,181 | Treatment results in males with breast cancer. | [
0.05380341783165932,
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0.06414742767810822,
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0... |
10,001,182 | Between 1948 and 1978, 39 previously untreated males with breast cancer received curative treatment at M. D. Anderson Hospital; an additional 30 males were referred for first treatment failure after outside definitive treatment. Of 21 patients who were treated with mastectomy, six had radical mastectomy alone, and 15 h... | [
0.06407969444990158,
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0.053378019481897354,
0.0206797793507576,
0.07021057605743408,
0.090846... |
10,001,183 | Testicular mass: an initial sign of colon carcinoma. | [
0.047633253037929535,
0.006408456712961197,
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0.02655734494328499,
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0.04262016341090202,
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0.0019144559046253562,
0.0533... |
10,001,184 | Molecular transformation of tumor adenylosuccinate synthetase and characteristics of its converting factor. | [
0.019718313589692116,
0.015612194314599037,
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0.035753414034843445,
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-... |
10,001,185 | The properties of adenylosuccinate synthetase [inosine monophosphate:L-aspartate ligase (guanosine 5'-diphosphate-forming) EC 6.3.4.4]) of rat Yoshida sarcoma ascites tumor cells changed during purification. The isoelectric points (pI) of the crude and purified enzymes were 5.0 and 5.9, respectively. The Km values of t... | [
-0.05226820334792137,
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0.03480719029903412,
0.021417634561657906,
-0.015141572803258896,
0.0003764618013519794,
0.01608865... |
10,001,186 | Cytokinetic and biochemical effects of 5-iminodaunorubicin in human colon carcinoma in culture. | [
0.012205241248011589,
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0.05193035677075386,
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0.0... |
10,001,187 | The semisynthetic anthracycline, 5-iminodaunorubicin (IM), was investigated to see whether modification of the benzoquinone moiety to produce a drug with low free radical potential would alter the cytotoxic and biochemical characteristics of this drug in comparison to Adriamycin (ADR), an agent with high free radical p... | [
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0.036147259175777435,
0.00237177568487823,
0.037565313279628754,
0.07124248892068863,
0.089... |
10,001,188 | Turnover and transport of plasma very-low-density lipoprotein triglycerides in mice bearing Ehrlich ascites carcinoma. | [
-0.03792275860905647,
-0.0716901645064354,
-0.05277293175458908,
0.000006159440999908838,
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-0.0615556538105011,
0.028998179361224174,
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-0.04759058356285095,
-0... |
10,001,189 | Effects of estrogens and antiestrogens on estrogen receptor dynamics and the induction of progesterone receptor in MCF-7 human breast cancer cells. | [
0.00001254229573532939,
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-0.05237579718232155,
0.009841038845479488,
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0.06358903646469116,
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-0.009194145910441875,
-0.015092854388058186,
... |
10,001,190 | Effects of rat urine fractionated by molecular weight on urinary bladder carcinogenesis. | [
-0.005737142637372017,
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-0.004537553526461124,
0.0521821565926075,
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0.05759096518158913,
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-0.0022903666831552982,
-0.024162840098142624,
-0.003410887438803911,
-0.0702969953417778,
0.1... |
10,001,191 | Monoclonal antibody-defined human lung cell surface protein antigens. | [
0.0011663426412269473,
-0.021012021228671074,
-0.00032488821307197213,
-0.11462737619876862,
0.034631360322237015,
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0.07711320370435715,
0.08878522366285324,
0.041038256138563156,
0.026412561535835266,
-0.0307278111577034,
-0.03354538604617119,
-0.027866140007972717,
... |
10,001,192 | Monoclonal antibodies were used to define four distinct antigens present on the surface of human lung tumors. Immunoprecipitation of the four antigens by monoclonal antibodies and sodium dodecyl sulfate:polyacrylamide gel electrophoresis reveals that they have distinct complex structures. Different patterns of expressi... | [
0.027019962668418884,
0.02815788798034191,
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0.0034078171011060476,
-0.0019898267928510904,
-0.04055042937397957,
0.0773690715432167,
0.08... |
10,001,193 | Correlation of circulating levels of a serum protein with triiodothyronine levels and hepatoma growth. | [
0.011380325071513653,
-0.03258111700415611,
-0.08862195909023285,
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0.021316269412636757,
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0.05... |
10,001,194 | In this communication, we provide evidence that proliferation of transplantable Morris hepatoma 7777 might to some extent be regulated by triiodothyronine and/or a specific serum protein, the levels of which are correlated with levels of triiodothyronine. The protein has an estimated molecular weight of 80,000 and migr... | [
-0.029785433784127235,
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0.04034446179866791,
0.01799914427101612,
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-0.009746460244059563,
0.... |
10,001,195 | Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide. | [
0.03810030221939087,
-0.11933449655771255,
-0.026442157104611397,
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0.09241984784603119,
0.... |
10,001,196 | Various vesicle structures and lipid compositions have been studied to identify the optimal type of liposome for delivery of the macrophage-activating agent muramyl dipeptide (MDP) to macrophages. Evaluation of the ability of liposomes to be phagocytosed by macrophages established that optimal initial rates of engulfme... | [
0.0509163998067379,
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0.0031577912159264088,
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0.038742098957300186,
-0.05515914410352707,
-0.010646479204297066,
0.01197134517133236,
0.065... |
10,001,197 | Significance of cellular pharmacokinetics for the cytotoxic effects of daunorubicin. | [
-0.04977186769247055,
-0.03345933184027672,
-0.09039430320262909,
0.0008753187721595168,
-0.026848772540688515,
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-0.09037815034389496,
0.0029582432471215725,
0.0075537338852882385,
0.0... |
10,001,198 | The effect of free and DNA-linked daunorubicin on the colony-forming ability of granulocyte-macrophage committed stem cells and spleen colony-forming cells (i.e., multipotent stem cells) from normal mice has been studied in vitro and in vivo. After incubation of bone marrow cells in short-term suspension cultures, both... | [
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0.04947371408343315,
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0.050737056881189346,
0.005997403059154749,
0.016... |
10,001,199 | Inhibition of pancreatic carcinogenesis by retinoids in azaserine-treated rats. | [
0.014187296852469444,
0.019837014377117157,
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0.02595977857708931,
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0.04907814413309097,
-0.018862755969166756,
0.020865721628069878,
0.03674723207950592,
0.047596849... |
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